JP2017537973A5 - - Google Patents

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Publication number
JP2017537973A5
JP2017537973A5 JP2017540317A JP2017540317A JP2017537973A5 JP 2017537973 A5 JP2017537973 A5 JP 2017537973A5 JP 2017540317 A JP2017540317 A JP 2017540317A JP 2017540317 A JP2017540317 A JP 2017540317A JP 2017537973 A5 JP2017537973 A5 JP 2017537973A5
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JP
Japan
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patient
level
composition
item
day
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JP2017540317A
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English (en)
Japanese (ja)
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JP2017537973A (ja
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Priority claimed from PCT/EP2015/074070 external-priority patent/WO2016059243A2/en
Publication of JP2017537973A publication Critical patent/JP2017537973A/ja
Publication of JP2017537973A5 publication Critical patent/JP2017537973A5/ja
Pending legal-status Critical Current

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JP2017540317A 2014-10-17 2015-10-16 バイオマーカーレベルを使用してsmad7アンチセンスオリゴヌクレオチドを投与するおよびモニタリングするための方法 Pending JP2017537973A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462065586P 2014-10-17 2014-10-17
US201462065596P 2014-10-17 2014-10-17
US62/065,586 2014-10-17
US62/065,596 2014-10-17
US201462085949P 2014-12-01 2014-12-01
US62/085,949 2014-12-01
PCT/EP2015/074070 WO2016059243A2 (en) 2014-10-17 2015-10-16 Methods for dosing and monitoring smad7 antisense oligonucleotide treatment using biomarker levels

Publications (2)

Publication Number Publication Date
JP2017537973A JP2017537973A (ja) 2017-12-21
JP2017537973A5 true JP2017537973A5 (enExample) 2018-11-29

Family

ID=54356321

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017540317A Pending JP2017537973A (ja) 2014-10-17 2015-10-16 バイオマーカーレベルを使用してsmad7アンチセンスオリゴヌクレオチドを投与するおよびモニタリングするための方法

Country Status (5)

Country Link
US (2) US20170233736A1 (enExample)
EP (2) EP3213070A2 (enExample)
JP (1) JP2017537973A (enExample)
CA (1) CA2964673A1 (enExample)
WO (1) WO2016059243A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20030149A1 (it) 2003-04-02 2004-10-03 Giuliani Spa Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
ES2627745T3 (es) 2008-11-13 2017-07-31 Nogra Pharma Limited Composiciones antisentido, y procedimientos de fabricación y uso de las mismas
US9791442B2 (en) 2011-09-15 2017-10-17 Nogra Pharma Limited Methods of monitoring responsiveness to anti-SMAD7 therapy
CN104487574B (zh) 2012-04-18 2017-07-07 诺格尔制药有限公司 治疗糖尿病和/或促进胰岛移植后存活的方法
US10006029B2 (en) 2013-03-15 2018-06-26 Nogra Pharma Limited Methods of treating colorectal cancer
RU2016147569A (ru) * 2014-05-09 2018-06-13 Ногра Фарма Лимитед Способы лечения воспалительного заболевания кишечника
US10337004B2 (en) 2014-10-17 2019-07-02 Nogra Pharma Limited Methods and compositions for treating a subject with a SMAD7 antisense oligonucleotide
MA41271A (fr) * 2014-12-26 2017-10-31 Celgene Alpine Invest Company Ii Llc Méthodes d'utilisation d'oligonucléotides antisens ciblant smad7
US11162097B2 (en) 2016-02-23 2021-11-02 Nogra Pharma Limited Methods of treating intestinal fibrosis using SMAD7 inhibition
AU2017312553B2 (en) 2016-08-15 2019-10-03 Intercontinental Great Brands Llc Multi-layer film and reclosable film package
EP3496947A1 (en) 2016-08-15 2019-06-19 Intercontinental Great Brands LLC Multi-layer film and reclosable film package

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159697A (en) 2000-01-19 2000-12-12 Isis Pharmaceuticals, Inc. Antisense modulation of Smad7 expression
ITRM20030149A1 (it) 2003-04-02 2004-10-03 Giuliani Spa Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
EP2352762A1 (en) * 2008-11-03 2011-08-10 Schering Corporation Inflammatory bowel disease biomarkers and related methods of treatment
ES2627745T3 (es) 2008-11-13 2017-07-31 Nogra Pharma Limited Composiciones antisentido, y procedimientos de fabricación y uso de las mismas
US9791442B2 (en) * 2011-09-15 2017-10-17 Nogra Pharma Limited Methods of monitoring responsiveness to anti-SMAD7 therapy
WO2013169353A1 (en) * 2012-05-11 2013-11-14 University Of Iowa Research Foundation Multimodal imaging methods using mesoporous silica nanoparticles
US10337004B2 (en) * 2014-10-17 2019-07-02 Nogra Pharma Limited Methods and compositions for treating a subject with a SMAD7 antisense oligonucleotide

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