JP2017530151A5 - - Google Patents
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- Publication number
- JP2017530151A5 JP2017530151A5 JP2017517678A JP2017517678A JP2017530151A5 JP 2017530151 A5 JP2017530151 A5 JP 2017530151A5 JP 2017517678 A JP2017517678 A JP 2017517678A JP 2017517678 A JP2017517678 A JP 2017517678A JP 2017530151 A5 JP2017530151 A5 JP 2017530151A5
- Authority
- JP
- Japan
- Prior art keywords
- burn
- composition
- skin graft
- cells
- recipient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 95
- 239000000203 mixture Substances 0.000 claims description 46
- 230000001172 regenerating effect Effects 0.000 claims description 44
- 208000027418 Wounds and injury Diseases 0.000 claims description 23
- 239000000654 additive Substances 0.000 claims description 9
- 230000000996 additive effect Effects 0.000 claims description 9
- 239000012634 fragment Substances 0.000 claims description 5
- 206010053615 Thermal burn Diseases 0.000 claims description 4
- 230000035876 healing Effects 0.000 claims description 4
- 208000025865 Ulcer Diseases 0.000 claims description 3
- 230000002708 enhancing effect Effects 0.000 claims description 3
- 231100000397 ulcer Toxicity 0.000 claims description 3
- 208000009043 Chemical Burns Diseases 0.000 claims 1
- 208000018380 Chemical injury Diseases 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 49
- 210000001519 tissue Anatomy 0.000 description 24
- 206010052428 Wound Diseases 0.000 description 17
- 210000002536 stromal cell Anatomy 0.000 description 15
- 210000000577 adipose tissue Anatomy 0.000 description 13
- 231100000241 scar Toxicity 0.000 description 12
- 230000001969 hypertrophic effect Effects 0.000 description 10
- 206010062575 Muscle contracture Diseases 0.000 description 6
- 208000006111 contracture Diseases 0.000 description 6
- 208000032544 Cicatrix Diseases 0.000 description 5
- 210000001185 bone marrow Anatomy 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 239000010410 layer Substances 0.000 description 5
- 210000002826 placenta Anatomy 0.000 description 5
- 230000037387 scars Effects 0.000 description 5
- 210000003491 skin Anatomy 0.000 description 5
- 210000003954 umbilical cord Anatomy 0.000 description 5
- 206010023201 Joint contracture Diseases 0.000 description 4
- 210000004381 amniotic fluid Anatomy 0.000 description 4
- 210000003683 corneal stroma Anatomy 0.000 description 4
- 210000003074 dental pulp Anatomy 0.000 description 4
- 230000002357 endometrial effect Effects 0.000 description 4
- 235000015110 jellies Nutrition 0.000 description 4
- 239000008274 jelly Substances 0.000 description 4
- 210000003205 muscle Anatomy 0.000 description 4
- 210000004623 platelet-rich plasma Anatomy 0.000 description 4
- 230000037390 scarring Effects 0.000 description 4
- 239000011229 interlayer Substances 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 210000000130 stem cell Anatomy 0.000 description 3
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 description 1
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 description 1
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 description 1
- 101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 description 1
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 description 1
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 description 1
- 102100033523 Thy-1 membrane glycoprotein Human genes 0.000 description 1
- 230000001464 adherent effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021064679A JP2021105041A (ja) | 2014-10-03 | 2021-04-06 | 熱傷の進行の緩和ならびに皮膚移植片の取り込みおよび治癒の改善における再生細胞の使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462059773P | 2014-10-03 | 2014-10-03 | |
| US62/059,773 | 2014-10-03 | ||
| PCT/US2015/053856 WO2016054592A1 (en) | 2014-10-03 | 2015-10-02 | Use of regenerative cells in mitigating burn progression and improving skin graft incorporation and healing |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021064679A Division JP2021105041A (ja) | 2014-10-03 | 2021-04-06 | 熱傷の進行の緩和ならびに皮膚移植片の取り込みおよび治癒の改善における再生細胞の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530151A JP2017530151A (ja) | 2017-10-12 |
| JP2017530151A5 true JP2017530151A5 (enExample) | 2018-11-15 |
| JP7303612B2 JP7303612B2 (ja) | 2023-07-05 |
Family
ID=55631662
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517678A Active JP7303612B2 (ja) | 2014-10-03 | 2015-10-02 | 熱傷の進行の緩和ならびに皮膚移植片の取り込みおよび治癒の改善における再生細胞の使用 |
| JP2021064679A Pending JP2021105041A (ja) | 2014-10-03 | 2021-04-06 | 熱傷の進行の緩和ならびに皮膚移植片の取り込みおよび治癒の改善における再生細胞の使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021064679A Pending JP2021105041A (ja) | 2014-10-03 | 2021-04-06 | 熱傷の進行の緩和ならびに皮膚移植片の取り込みおよび治癒の改善における再生細胞の使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170296697A1 (enExample) |
| EP (1) | EP3200843A4 (enExample) |
| JP (2) | JP7303612B2 (enExample) |
| CA (1) | CA2963468A1 (enExample) |
| WO (1) | WO2016054592A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9580678B2 (en) | 2013-06-21 | 2017-02-28 | The Regents Of The University Of California | Microfluidic tumor tissue dissociation device |
| JP7303612B2 (ja) * | 2014-10-03 | 2023-07-05 | サイトリ・セラピューティクス株式会社 | 熱傷の進行の緩和ならびに皮膚移植片の取り込みおよび治癒の改善における再生細胞の使用 |
| US10078897B2 (en) * | 2015-04-24 | 2018-09-18 | Medstar Health | Systems and methods for identifying burn wound conversion |
| EP3370698B1 (en) | 2015-11-03 | 2022-01-26 | Zoetis Services LLC | Sol-gel polymer composites and uses thereof |
| US10722540B1 (en) | 2016-02-01 | 2020-07-28 | The Regents Of The University Of California | Microfluidic device and method for shear stress-induced transformation of cells |
| BR112018075194B1 (pt) | 2016-06-08 | 2023-01-10 | The Regents Of The University Of California | Método e dispositivo para processar amostras |
| CN111989110A (zh) * | 2018-04-04 | 2020-11-24 | 赛丹思科大学 | 携带cd31的干细胞和祖细胞 |
| CN109157676A (zh) * | 2018-08-31 | 2019-01-08 | 谭亚 | 一种重塑复合生物羊膜的制备方法 |
| EP3909593A1 (en) | 2020-05-15 | 2021-11-17 | Rigshospitalet | Stem cells for treating skin lesions |
| CN115501125A (zh) * | 2022-10-20 | 2022-12-23 | 澳门科技大学 | 用于修复皮肤损伤的h2s供体凝胶及h2s供体凝胶制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU709010B2 (en) * | 1995-08-25 | 1999-08-19 | Lifecell Corporation | Reconstituted skin |
| AU2808397A (en) * | 1996-04-26 | 1997-11-19 | Case Western Reserve University | Skin regeneration using mesenchymal stem cells |
| NZ506510A (en) * | 1998-02-24 | 2003-03-28 | Advanced Tissue Sciences Inc | A permanent skin replacement comprising allogenic epithelial cells cultured in vitro and autologous epithelial cells |
| CA2536096A1 (en) * | 2004-01-30 | 2005-08-18 | Angiotech International Ag | Compositions and methods for treating contracture |
| WO2006074075A2 (en) * | 2004-12-30 | 2006-07-13 | Primegen Biotech, Llc | Adipose-derived stem cells for tissue regeneration and wound healing |
| US20070274967A1 (en) * | 2006-05-24 | 2007-11-29 | Calvin Cao | Compositions and methods of treating burn victims using stem cells |
| WO2009020650A2 (en) * | 2007-08-08 | 2009-02-12 | Pervasis Therapeutics, Inc. | Materials and methods for treating and managing wounds and the effects of trauma |
| US20090148416A1 (en) * | 2007-12-06 | 2009-06-11 | Ekaterina Vorotelyak | Angiogenically induced transplants and methods for their use and manufacture |
| WO2010042991A1 (en) * | 2008-10-15 | 2010-04-22 | Novogen Research Pty Ltd | Methods of treatment utilising glucan formulations |
| FI20095355A0 (fi) * | 2009-04-01 | 2009-04-01 | Helsingin Yliopisto | Regeneroituva aktiivinen matriisi ja sen käytöt |
| US9636362B2 (en) * | 2010-03-04 | 2017-05-02 | The Board Of Trustees Of The Leland Stanford Junior University | Pullulan regenerative matrix |
| JP7303612B2 (ja) * | 2014-10-03 | 2023-07-05 | サイトリ・セラピューティクス株式会社 | 熱傷の進行の緩和ならびに皮膚移植片の取り込みおよび治癒の改善における再生細胞の使用 |
-
2015
- 2015-10-02 JP JP2017517678A patent/JP7303612B2/ja active Active
- 2015-10-02 US US15/515,870 patent/US20170296697A1/en not_active Abandoned
- 2015-10-02 CA CA2963468A patent/CA2963468A1/en not_active Abandoned
- 2015-10-02 EP EP15847625.9A patent/EP3200843A4/en not_active Withdrawn
- 2015-10-02 WO PCT/US2015/053856 patent/WO2016054592A1/en not_active Ceased
-
2021
- 2021-04-06 JP JP2021064679A patent/JP2021105041A/ja active Pending
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