JP2017523260A - シクロデキストリン系のポリアニオン性デンドリマーおよび非イオン性デンドリマー - Google Patents

シクロデキストリン系のポリアニオン性デンドリマーおよび非イオン性デンドリマー Download PDF

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JP2017523260A
JP2017523260A JP2016569937A JP2016569937A JP2017523260A JP 2017523260 A JP2017523260 A JP 2017523260A JP 2016569937 A JP2016569937 A JP 2016569937A JP 2016569937 A JP2016569937 A JP 2016569937A JP 2017523260 A JP2017523260 A JP 2017523260A
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compound
group
cyclodextrin
substituted
alkyl
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Japanese (ja)
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JP2017523260A5 (enExample
Inventor
チャンチュン リン
チャンチュン リン
ピン ジャン
ピン ジャン
Original Assignee
ユーティーアイ リミテッド パートナーシップ
ユーティーアイ リミテッド パートナーシップ
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Publication of JP2017523260A publication Critical patent/JP2017523260A/ja
Publication of JP2017523260A5 publication Critical patent/JP2017523260A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16—Cyclodextrin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
JP2016569937A 2014-05-29 2015-03-31 シクロデキストリン系のポリアニオン性デンドリマーおよび非イオン性デンドリマー Pending JP2017523260A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462004364P 2014-05-29 2014-05-29
US62/004,364 2014-05-29
US201462060787P 2014-10-07 2014-10-07
US62/060,787 2014-10-07
PCT/CA2015/050254 WO2015179963A1 (en) 2014-05-29 2015-03-31 Cyclodextrin-based polyanionic and non-ionic dendrimers

Publications (2)

Publication Number Publication Date
JP2017523260A true JP2017523260A (ja) 2017-08-17
JP2017523260A5 JP2017523260A5 (enExample) 2018-05-17

Family

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JP2016569937A Pending JP2017523260A (ja) 2014-05-29 2015-03-31 シクロデキストリン系のポリアニオン性デンドリマーおよび非イオン性デンドリマー

Country Status (5)

Country Link
US (1) US10662260B2 (enExample)
EP (1) EP3149052A4 (enExample)
JP (1) JP2017523260A (enExample)
CA (1) CA2950610A1 (enExample)
WO (1) WO2015179963A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9950080B2 (en) * 2013-10-01 2018-04-24 Uti Limited Partnership Amphiphilic cyclodextrin-based glycodendrimers
JP2018510912A (ja) * 2015-04-08 2018-04-19 リン，チャン−チュン ポリアニオン性および非イオン性のシクロデキストリン系デンドリマーの医薬組成物およびその使用
US10894839B2 (en) 2016-06-23 2021-01-19 Synthon B.V. Process for making Sugammadex
US20190275073A1 (en) * 2016-07-22 2019-09-12 Ecole polytechnique fédérale de Lausanne (EPFL) Virucidal compounds and uses thereof
CN108164569A (zh) * 2018-02-08 2018-06-15 西北工业大学 一种以β-CD为核的树枝状大分子及其合成方法
IL280936B2 (en) 2018-09-04 2024-12-01 Ecole Polytechnique Fed Lausanne Epfl Virucidal nanoparticles and use thereof against influenza virus

Citations (2)

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JP2002532440A (ja) * 1998-12-18 2002-10-02 デュポン ファーマシューティカルズ カンパニー ビトロネクチン受容体拮抗剤薬剤
US7332149B1 (en) * 1998-12-18 2008-02-19 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals

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US6506717B1 (en) 1999-01-20 2003-01-14 The Procter & Gamble Company Dishwashing compositions comprising modified alkybenzene sulfonates
TWI242015B (en) 1999-11-29 2005-10-21 Akzo Nobel Nv 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block
DE50113779D1 (de) * 2000-11-08 2008-05-08 Greenfield Ag Verfahren zum Befüllen eines Fahrzeugtanks mit Gas
FR2852959B1 (fr) * 2003-03-28 2008-02-15 Centre Nat Rech Scient Nouveaux derives de cyclodextrines, leur procede de preparation et leur utilisation notamment pour solubilisation de substances pharmacologiquement actives
FR2903987B1 (fr) 2006-07-21 2012-12-21 Centre Nat Rech Scient Nouveaux derives de cyclodextrines amphiphiles, leur utilisation dans les domaines pharmaceutiques,cosmetiques, alimentaires et leur application a la production de nouveaux nanosystemes
US7635773B2 (en) * 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
WO2010017328A2 (en) * 2008-08-06 2010-02-11 Rgo Biosciences Llc Cyclodextrin conjugates
CN101591402B (zh) * 2009-05-05 2011-11-30 杭州奥默医药技术有限公司 6-脱氧砜类环糊精衍生物及其制备方法
US8492538B1 (en) * 2009-06-04 2013-07-23 Jose R. Matos Cyclodextrin derivative salts
DE102010012281A1 (de) * 2010-03-22 2011-09-22 Fresenius Medical Care Deutschland Gmbh Pharmazeutische Zusammensetzungen enthaltend substituiertes 6-Deoxy-6-sulfanylcyclodextrin
DK3702374T3 (da) 2012-02-15 2022-06-27 Cydex Pharmaceuticals Inc Fremsgangsmåde til fremstilling for cyclodextrin-derivater

Patent Citations (2)

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JP2002532440A (ja) * 1998-12-18 2002-10-02 デュポン ファーマシューティカルズ カンパニー ビトロネクチン受容体拮抗剤薬剤
US7332149B1 (en) * 1998-12-18 2008-02-19 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BIOCONJUGATE CHEMISTRY, vol. Vol.14(5), JPN6019010041, 2003, pages 899 - 908, ISSN: 0004217518 *
JOURNAL OF COLLOID AND INTERFACE SCIENCE, vol. Vol.279(2), JPN6019010036, 2004, pages 425 - 432, ISSN: 0004217514 *
JOURNAL OF POLYMER SCIENCE, PART A: POLYMER CHEMISTRY, vol. Vol.45(22), JPN6019010035, 2007, pages 5149 - 5155, ISSN: 0004217513 *
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. Vol.128(28), JPN6019010038, 2006, pages 8994 - 8995, ISSN: 0004217515 *
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. Vol.129(20), JPN6019010040, 2007, pages 6396 - 6397, ISSN: 0004217517 *
MACROMOLECULES, vol. Vol.40(9), JPN6019010039, 2007, pages 3256 - 3262, ISSN: 0004217516 *

Also Published As

Publication number Publication date
US10662260B2 (en) 2020-05-26
US20170107304A1 (en) 2017-04-20
WO2015179963A1 (en) 2015-12-03
EP3149052A1 (en) 2017-04-05
CA2950610A1 (en) 2015-12-03
EP3149052A4 (en) 2018-01-03

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