JP2017500547A - 心臓障害のためのバイオマーカー - Google Patents

心臓障害のためのバイオマーカー Download PDF

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Publication number
JP2017500547A
JP2017500547A JP2016530994A JP2016530994A JP2017500547A JP 2017500547 A JP2017500547 A JP 2017500547A JP 2016530994 A JP2016530994 A JP 2016530994A JP 2016530994 A JP2016530994 A JP 2016530994A JP 2017500547 A JP2017500547 A JP 2017500547A
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Prior art keywords
tntuorf
peptide
subject
troponin
cardiac
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JP2016530994A
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Japanese (ja)
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JP2017500547A5 (enExample
Inventor
ジャクリーン アマンダ リー，
ジャクリーン アマンダ リー，
クリストファー ジョゼフ ペンバートン，
クリストファー ジョゼフ ペンバートン，
Original Assignee
オタゴ イノベーション リミテッド
オタゴ イノベーション リミテッド
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Publication of JP2017500547A publication Critical patent/JP2017500547A/ja
Publication of JP2017500547A5 publication Critical patent/JP2017500547A5/ja
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716—Muscle proteins, e.g. myosin, actin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2016530994A 2013-11-15 2014-11-14 心臓障害のためのバイオマーカー Pending JP2017500547A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361904957P 2013-11-15 2013-11-15
US61/904,957 2013-11-15
PCT/NZ2014/000234 WO2015072865A1 (en) 2013-11-15 2014-11-14 Biomarker for cardiac disorders

Publications (2)

Publication Number Publication Date
JP2017500547A true JP2017500547A (ja) 2017-01-05
JP2017500547A5 JP2017500547A5 (enExample) 2017-12-28

Family

ID=53057709

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016530994A Pending JP2017500547A (ja) 2013-11-15 2014-11-14 心臓障害のためのバイオマーカー

Country Status (7)

Country Link
US (2) US9784749B2 (enExample)
EP (1) EP3069146A4 (enExample)
JP (1) JP2017500547A (enExample)
CN (1) CN105980857B (enExample)
AU (1) AU2014351090A1 (enExample)
CA (1) CA2930790A1 (enExample)
WO (1) WO2015072865A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022013481A2 (pt) * 2020-01-08 2022-09-13 Regeneron Pharma Uso de aminoácidos para aumentar o sinal em análises espectro de massa
WO2025040754A1 (en) * 2023-08-22 2025-02-27 Roche Diagnostics Gmbh Monitoring of cardiovascular markers in interstitial fluid and its application in assessment of heart failure

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006526140A (ja) * 2002-12-24 2006-11-16 バイオサイト インコーポレイテッド 鑑別診断のためのマーカーおよびその使用方法
US20070172888A1 (en) * 2006-01-25 2007-07-26 Klaus Hallermayer Measuring troponin antibodies to assess cardiovascular risk
WO2008030122A1 (en) * 2006-09-07 2008-03-13 University Of Otago Biomarkers
JP2009524807A (ja) * 2006-01-25 2009-07-02 エフ．ホフマン−ラ ロシュ アーゲー 抗トロポニン抗体および心臓血管リスク
EP2261669A1 (en) * 2001-05-04 2010-12-15 Alere San Diego, Inc. Diagnostic markers of acute coronary syndromes and methods of use thereof
WO2013017690A2 (en) * 2011-08-03 2013-02-07 Roche Diagnostics Gmbh Troponin based rule in and rule out algorithm of myocardial infarction

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3922873A1 (de) 1989-04-25 1990-10-31 Boehringer Mannheim Gmbh Spezifische antikoerper gegen troponin t, ihre herstellung und verwendung in einem reagenz zur bestimmung von hermuskelnekrosen
US6991907B1 (en) 1995-04-18 2006-01-31 Biosite, Inc. Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
CN101371144A (zh) * 2006-01-25 2009-02-18 霍夫曼-拉罗奇有限公司 抗肌钙蛋白抗体和心血管风险
EP1887361A1 (en) * 2006-08-07 2008-02-13 Bio-Rad Pasteur Method for the prediction of vascular events

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2261669A1 (en) * 2001-05-04 2010-12-15 Alere San Diego, Inc. Diagnostic markers of acute coronary syndromes and methods of use thereof
JP2006526140A (ja) * 2002-12-24 2006-11-16 バイオサイト インコーポレイテッド 鑑別診断のためのマーカーおよびその使用方法
US20070172888A1 (en) * 2006-01-25 2007-07-26 Klaus Hallermayer Measuring troponin antibodies to assess cardiovascular risk
JP2009524807A (ja) * 2006-01-25 2009-07-02 エフ．ホフマン−ラ ロシュ アーゲー 抗トロポニン抗体および心臓血管リスク
WO2008030122A1 (en) * 2006-09-07 2008-03-13 University Of Otago Biomarkers
JP2010506145A (ja) * 2006-09-07 2010-02-25 ユニバーシティー オブ オタゴ バイオマーカー
WO2013017690A2 (en) * 2011-08-03 2013-02-07 Roche Diagnostics Gmbh Troponin based rule in and rule out algorithm of myocardial infarction

Also Published As

Publication number Publication date
EP3069146A1 (en) 2016-09-21
CN105980857B (zh) 2018-07-13
EP3069146A4 (en) 2017-04-05
CA2930790A1 (en) 2015-05-21
CN105980857A (zh) 2016-09-28
US20160299154A1 (en) 2016-10-13
AU2014351090A1 (en) 2016-06-16
WO2015072865A1 (en) 2015-05-21
US9784749B2 (en) 2017-10-10
US20180156822A1 (en) 2018-06-07

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