JP2017192662A - Percutaneous administration device storage body - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a percutaneous administration device storage body capable of enhancing a protection function of a percutaneous administration device by a storage part.SOLUTION: A percutaneous administration device storage body 10 comprises: a percutaneous administration device 20; and a storage part 30 for storing the percutaneous administration device 20. The storage part 30 comprises: a first body part 40 which faces a first surface 22S of a base substrate 22 of a microneedle 21; and a second body part 50 which faces a non-adhesive surface 24T of an adhesive sheet 24, and comprises a space where the percutaneous administration device 20 is positioned, between the first body part 40 and the second body part 50. A body pair formed of the first body part 40 and the second body part 50 has a fixing structure for fixing a relative position of the first body part 40 to the second body part 50, in a releasable manner, on outside of the percutaneous administration device 20 in view from a direction facing the first surface 22S.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a percutaneous administration device housing containing a transdermal administration device used for drug administration.

  The transdermal administration device includes an administration unit for administering a drug from the skin to the administration target. A microneedle, which is an example of an administration unit, includes a plurality of protrusions having a needle shape and a plate-like base, and the plurality of protrusions are arranged on the surface of the base. And the transdermal administration device is equipped with the adhesive sheet for fixing a microneedle to skin with these microneedles, and the protection sheet which protects the adhesive surface which an adhesive sheet has (for example, refer patent document 1). .

  The user of the transdermal administration device first peels off the protective sheet from the adhesive sheet when administering the drug. Subsequently, the user presses the surface of the base of the microneedle against the skin of the drug administration site, and fixes the microneedle to the skin with an adhesive sheet. As a result, the projecting portion perforates the skin, and the drug is fed into the body of the administration target through the hole formed by the projecting portion. Since the size of the protrusion is very small, the method of administering a drug using microneedles can suppress the occurrence of pain when the skin is perforated.

JP 2014-147837 A

  By the way, the transdermal administration device is accommodated in an accommodating portion that is a container for protecting the transdermal administration device, and is transported or stored as a transdermal administration device container including the transdermal administration device and the accommodating portion. .

In such a housing part, a function capable of suitably protecting the transdermal administration device until the transdermal administration device is taken out of the accommodation unit, for example, even when the transdermal administration device container is being transported. Is required. Specifically, for example, it is desirable that the housing portion is less likely to be opened due to vibration or the like generated during transportation.
An object of this invention is to provide the transdermal administration device container which can improve the protection function of the transdermal administration device by an accommodating part.

  A transdermal administration device container that solves the above-described problems is a transdermal administration device container that includes a transdermal administration device and a housing unit that accommodates the transdermal administration device. An administration part comprising a base having a first surface and a second surface opposite to the first surface, a protrusion protruding from the first surface, and an adhesive having the second surface attached thereto A pressure-sensitive adhesive sheet having a surface and a non-adhesive surface opposite to the pressure-sensitive adhesive surface, wherein a part of the pressure-sensitive adhesive surface protrudes outside the substrate when viewed from a direction facing the first surface. The adhesive sheet, and a protective sheet attached to a region of the adhesive surface that protrudes from the base body, and the housing portion includes a first main body portion that faces the first surface of the base body, A second main body portion facing the non-adhesive surface of the adhesive sheet; A body having a space where the transdermal administration device is located between the first body part and the second body part, and comprising the first body part and the second body part The pair has a fixing structure for releasably fixing a relative position of the first main body portion with respect to the second main body portion outside the transdermal administration device when viewed from the direction facing the first surface. Prepare.

  According to the above configuration, since the relative position of the first main body portion with respect to the second main body portion is accurately fixed, the first main body is also vibrated during the transport of the transdermal administration device container due to vibrations and the like generated during the transport. It is possible to prevent the housing portion from being unsealed due to the position of the portion being shifted with respect to the second body portion. Therefore, the protection function of the transdermal administration device by the accommodating part is enhanced.

In the above-described configuration, the fixing structure is a fitting structure in which the first main body portion and the second main body portion are fitted to each other, and the housing portion is formed by releasing the fitting in the fitting structure. The space between the main body and the second main body may be configured to be openable to the outside.
According to the said structure, compared with the structure where the 1st main-body part and the 2nd main-body part are mutually fixed by adhesion | attachment etc., opening of an accommodating part is easy.
The said structure WHEREIN: The said fitting structure may be located in the cyclic | annular form surrounding the said transdermal administration device seeing from the direction facing the said 1st surface.
According to the said structure, the relative position with respect to the 2nd main-body part of a 1st main-body part is fixed more firmly.

The said structure WHEREIN: The said main body pair may be equipped with the said some fitting structure on the outer side rather than the said transdermal administration device seeing from the direction facing the said 1st surface.
According to the said structure, the relative position with respect to the 2nd main-body part of a 1st main-body part is fixed more firmly.
In the configuration described above, the main body pair includes a portion in which an end portion of the first main body portion does not overlap the second main body portion when viewed from the direction facing the first surface, and the second main body You may satisfy | fill at least one of providing the part which the edge part of a part does not overlap with the said 1st main-body part.

  According to the above configuration, the user of the transdermal administration device picks up and lifts the portion that does not overlap with the other main body portion of either the first main body portion or the second main body portion, thereby pulling the first main body portion and the second main body portion. The main body can be easily separated. Therefore, it is easy to open the housing portion.

  In the above configuration, the first main body portion includes a first plate-like portion having a plate shape extending in a direction along the first surface, and the second main body portion extends in a direction along the first surface. A second plate-like portion having a plate shape, and the first plate-like portion is located outside the transdermal administration device in the first plate-like portion when viewed from the direction facing the first surface. And a plurality of first projecting portions arranged on the outside of the transdermal administration device, wherein the second plate-shaped portion is viewed from a direction facing the first surface. The second plate-shaped portion has a shape projecting outwardly with respect to the transdermal administration device, and includes a plurality of second projecting portions arranged on the outer side of the transdermal administration device, When viewed from the direction facing the first surface, the first projecting portion is disposed between two first projecting portions adjacent to each other. Overhang may be located.

  According to the above configuration, the user of the transdermal administration device easily separates the first main body portion and the second main body portion by pulling the first overhang portion and the second overhang portion in opposite directions. can do. Therefore, it is easy to open the housing portion.

In the above configuration, the fixing structure includes a fulcrum part, and the body pair is a rotation in a direction along the first surface with the fulcrum part as a center of rotation, and the first body part has the rotation. It may be configured to be able to rotate relative to the second body portion, and may be configured to be able to open the space between the first body portion and the second body portion to the outside by the rotation.
According to the said structure, compared with the structure where the 1st main-body part and the 2nd main-body part are mutually fixed by adhesion | attachment etc., opening of an accommodating part is easy.

  In the above configuration, the fixing structure includes a positioning structure, and the positioning structure is a structure in which one of the first main body portion and the second main body portion is hooked on the other. The structure which suppresses relative rotation with respect to the said 2nd main-body part may be sufficient.

  According to the above configuration, in the configuration in which the housing portion is opened by the rotation of the main body portion, the relative position of the first main body portion to the second main body portion can be accurately fixed in a state before the housing portion is opened. it can.

  In the above configuration, one of the first main body and the second main body is a target main body, and the target main body includes a support plate that supports the transdermal administration device, the support plate, When viewed from the opposite direction, at least one of an outer peripheral portion surrounding the support plate portion and disposed at a position elevated from the support plate portion and an outer edge of the support plate portion inclined with respect to the support plate portion. And an inclined portion that connects at least a part of the inner peripheral edge of the outer peripheral portion.

  According to the said structure, the part which supports the transdermal administration device in the object main-body part and the part which protrudes in the circumference | surroundings are connected gently. Therefore, the user can slide the transdermal administration device along the inclined portion or slide the finger under the transdermal administration device along the inclined portion to pick the transdermal administration device. The skin administration device can be removed from the subject body. Therefore, it is easy to take out the transdermal administration device from the container.

  In the above configuration, the target main body includes a plurality of bulges raised from the inclined portion, and the two bulges included in the plurality of bulges as viewed from a direction facing the support plate are You may arrange | position in the position which pinches | interposes a transdermal administration device.

  According to the above configuration, in the state where the transdermal administration device is accommodated in the accommodating portion, the transdermal administration device is sandwiched between the two raised portions, so that the transdermal administration device is opened when the accommodating portion is opened. Is prevented from moving in the direction along the first surface of the substrate. Therefore, when the container is opened, the transdermal administration device can be prevented from sliding off the target main body.

  The said structure WHEREIN: The said protective sheet has the opposing surface turned to the said adhesion surface, and the non-opposing surface which is a surface on the opposite side to the said opposing surface, The said 1st main-body part is the said protective sheet. A first opposing portion that opposes the non-opposing surface; and the second main body portion includes a second opposing portion that opposes the non-adhesive surface of the adhesive sheet, the first opposing portion and the second opposing portion. Is the length between the first facing portion and the second facing portion along the direction facing the first surface across the space where the transdermal administration device is located. It may be less than the total length of the thickness of the sheet and the thickness of the pressure-sensitive adhesive sheet.

  According to the above configuration, the adhesive sheet and the protective sheet are sandwiched between the first facing portion and the second facing portion, and these sheets are pressed by the first facing portion and the second facing portion. The position of the transdermal administration device inside the unit is stabilized.

  ADVANTAGE OF THE INVENTION According to this invention, the protective function of the transdermal administration device by a accommodating part can be improved in a transdermal administration device container.

The disassembled perspective view which shows the perspective structure of a transdermal administration device container about 1st Embodiment of a transdermal administration device container. Sectional drawing which shows the cross-section of the transdermal administration device in 1st Embodiment. The perspective view which shows the perspective structure of the accommodating part in 1st Embodiment. The top view which shows the planar structure of the accommodating part in 1st Embodiment. The front view which shows the front structure of the accommodating part in 1st Embodiment. FIG. 6 is a cross-sectional view of the housing portion in the first embodiment, showing a cross-sectional structure taken along line 6-6 in FIG. 4; The end elevation which shows typically the cross-sectional structure of the transdermal administration device container of 1st Embodiment. The disassembled perspective view which shows the perspective structure of a transdermal administration device container about 2nd Embodiment of a transdermal administration device container. The perspective view which shows the perspective structure of the accommodating part in 2nd Embodiment. The top view which shows the planar structure of the accommodating part in 2nd Embodiment. The front view which shows the front structure of the accommodating part in 2nd Embodiment. FIG. 12 is a cross-sectional view of the storage section in the second embodiment, showing a cross-sectional structure taken along line 12-12 in FIG. 10; FIG. 13 is a cross-sectional view illustrating a cross-sectional structure of the accommodating portion according to the second embodiment and taken along line 13-13 in FIG. 10. The end elevation which shows typically the cross-sectional structure of the transdermal administration device container of 2nd Embodiment. The disassembled perspective view which shows the perspective structure of a transdermal administration device container about 3rd Embodiment of a transdermal administration device container. The top view which shows the planar structure of the accommodating part in 3rd Embodiment. The front view which shows the front structure of the accommodating part in 3rd Embodiment. FIG. 18 is a cross-sectional view of the storage section in the third embodiment, showing a cross-sectional structure taken along line 18-18 in FIG. 16; FIG. 19 is a cross-sectional view illustrating a cross-sectional structure taken along line 19-19 in FIG. Sectional drawing which shows an example of the cross-section of the fitting convex part in the accommodating part of 3rd Embodiment. Sectional drawing which shows an example of the cross-section of the fitting convex part in the accommodating part of 3rd Embodiment. The end elevation which shows typically the cross-sectional structure of the transdermal administration device container of 3rd Embodiment. The figure which shows the state which the 1st main-body part rotated about the transdermal administration device container of 3rd Embodiment. The disassembled perspective view which shows the perspective structure of a transdermal administration device container about 4th Embodiment of a transdermal administration device container. The top view which shows the planar structure of the accommodating part in 4th Embodiment. The front view which shows the front structure of the accommodating part in 4th Embodiment. FIG. 26 is a cross-sectional view of the accommodating part in the fourth embodiment, showing a cross-sectional structure taken along line 27-27 in FIG. 25; The end elevation which shows typically the cross-sectional structure of the transdermal administration device container of 4th Embodiment.

(First embodiment)
With reference to FIGS. 1-7, 1st Embodiment of a transdermal administration device container is described.
[Configuration of transdermal device container]
With reference to FIG. 1, the whole structure of a transdermal administration device container is demonstrated.
As shown in FIG. 1, the transdermal administration device housing 10 includes a transdermal administration device 20 and a housing 30 that houses the transdermal administration device 20.

  The transdermal administration device 20 includes a microneedle 21 which is an example of an administration unit, an adhesive sheet 24 for fixing the microneedle 21 to a drug administration target, and a protective sheet 28 for protecting the adhesive surface of the adhesive sheet 24. I have.

  The accommodating part 30 is composed of a first main body part 40 and a second main body part 50, and the first main body part so as to sandwich the transdermal administration device 20 between the first main body part 40 and the second main body part 50. The transdermal administration device 20 is accommodated in the space between 40 and the second main body 50.

  In the description of the first embodiment, a direction along the direction in which the first main body portion 40 and the second main body portion 50 are overlapped, and a portion of the second main body portion 50 that is directed to the outside of the accommodating portion 30; The facing direction is the reference direction. That is, the reference direction is a direction along the direction in which the first main body portion 40 and the second main body portion 50 are overlapped, and is opposed to the portion of the first main body portion 40 that is directed to the inside of the housing portion 30. Direction.

[Configuration of transdermal administration device]
The detailed configuration of the transdermal administration device 20 will be described with reference to FIG.
As shown in FIG. 2, the microneedle 21 includes a base 22 having a plate shape and a protrusion 23 protruding from the base 22. The base 22 has a first surface 22S that is a surface on which the protrusion 23 is positioned, and a second surface 22T that is a surface opposite to the first surface 22S. The first surface 22S is a base of the protrusion 23. Supports the edge. That is, the protrusion 23 protrudes from the first surface 22S.

  The shape of the base body 22 as viewed from the direction facing the first surface 22S is not particularly limited, and the base body 22 may be circular, elliptical, rectangular, or these shapes. May have different shapes. In the example shown as 1st Embodiment, the shape of the base | substrate 22 seen from the direction facing the 1st surface 22S is an elliptical shape.

  The shape of the protrusion 23 may be a conical shape or a pyramid shape. Further, the protruding portion 23 may have a shape in which the tip is not sharp, for example, a cylindrical shape or a prismatic shape. Further, the protruding portion 23 may have a shape in which two or more solids are combined, such as a shape in which cones are stacked on a cylinder. In short, the protrusion 23 may have any shape that can pierce the skin. Further, a constriction or a step may be formed on the side wall of the protrusion 23, or a groove or a hole may be formed.

  The number of protrusions 23 included in the microneedle 21 is not particularly limited as long as it is 1 or more. When the microneedle 21 includes a plurality of protrusions 23, the plurality of protrusions 23 may be regularly arranged on the first surface 22S of the base 22 or may be irregularly arranged. For example, the plurality of protrusions 23 are arranged in a lattice shape or a concentric shape.

  The length H of the protrusion 23 is the length from the first surface 22S to the tip of the protrusion 23 in the thickness direction of the base 22, that is, in the direction orthogonal to the first surface 22S of the base 22. The length H of the protrusion 23 is preferably 10 μm or more and 1000 μm or less, and the length H of the protrusion 23 is a depth necessary for a hole formed in the target of drilling by the protrusion 23 within this range. It is decided accordingly. When the target of perforation is human skin and the bottom of the hole is set in the stratum corneum, the length H is preferably 10 μm or more and 300 μm or less, and more preferably 30 μm or more and 200 μm or less. When the bottom of the hole is set to a depth that penetrates the stratum corneum and does not reach the nerve layer, the length H is preferably 200 μm or more and 700 μm or less, more preferably 200 μm or more and 500 μm or less, More preferably, it is 200 μm or more and 300 μm or less. When the depth of the hole reaches the dermis, the length H is preferably 200 μm or more and 500 μm or less. When the depth of the hole reaches the epidermis, the length H is preferably 200 μm or more and 300 μm or less.

The width D of the protrusion 23 is the maximum value of the length of the protrusion 23 in the direction along the first surface 22S of the base 22, that is, the direction parallel to the first surface 22S. For example, when the protrusion 23 has a regular quadrangular pyramid shape or a regular quadrangular prism shape, the length of the diagonal line in the square defined by the bottom of the protrusion 23 on the first surface 22S of the base 22 is the width D of the protrusion 23. It is. For example, when the protrusion 23 has a conical shape or a columnar shape, the diameter of a circle defined by the bottom of the protrusion 23 is the width D of the protrusion 23. The width D of the protrusion 23 is preferably 1 μm or more and 300 μm or less.
The aspect ratio A (A = H / D), which is the ratio of the length H to the width D of the protrusion 23, is preferably 1 or more and 10 or less.

  When the tip of the projection 23 is formed in a sharp shape and the projection 23 forms a hole having a depth penetrating the stratum corneum, the tip angle θ of the projection 23 is preferably 5 ° or more and 30 ° or less. More preferably, the angle is 10 ° or more and 20 ° or less. The tip angle θ is the maximum value of the angle formed by the tip of the protrusion 23 in the cross section along the thickness direction of the base body 22. For example, when the projecting portion 23 has a regular quadrangular pyramid shape, the tip angle θ of the projecting portion 23 is an apex angle of a triangle having a square diagonal line defining the bottom of the projecting portion 23 as a base and a vertex of the regular pyramid as a vertex. is there.

  The width D, the aspect ratio A, and the tip angle θ of the protrusion 23 are determined according to the volume required for the hole formed by the protrusion 23. If the length H, the width D, the aspect ratio A, and the tip angle θ are within the above ranges, the shape of the protrusion 23 is a shape suitable for forming a hole in the skin.

  The pressure-sensitive adhesive sheet 24 includes a base material sheet 26 and a pressure-sensitive adhesive layer 25 that covers one of the two surfaces of the base material sheet 26. The surface of the adhesive layer 25 opposite to the surface in contact with the base material sheet 26 is the adhesive surface 24S of the adhesive sheet 24, and the surface of the base material sheet 26 opposite to the surface in contact with the adhesive layer 25 is the adhesive sheet. 24 non-adhesive surfaces 24T. That is, in the adhesive sheet 24, the non-adhesive surface 24T is a surface opposite to the adhesive surface 24S. The second surface 22T of the base 22 is attached to the central portion of the adhesive surface 24S, whereby the base 22 of the microneedle 21 is attached to the adhesive sheet 24.

  When viewed from the direction facing the first surface 22S, the outer shape of the adhesive sheet 24 is larger than the outer shape of the base body 22, and the adhesive sheet is placed outside the base body 22 over the entire outer periphery of the base body 22 so as to surround the base body 22. A part of the adhesive surface 24S of 24 protrudes. The shape of the pressure-sensitive adhesive sheet 24 viewed from the direction facing the first surface 22S is not particularly limited, and the pressure-sensitive adhesive sheet 24 may be circular or elliptical, rectangular, or these You may have a shape different from a shape. In the example shown as 1st Embodiment, the shape of the adhesive sheet 24 seen from the direction facing the 1st surface 22S is an elliptical shape.

  The protective sheet 28 is affixed to an area that protrudes outside the base 22 in the adhesive surface 24 </ b> S of the adhesive sheet 24. When viewed from the direction facing the first surface 22 </ b> S, the outer shape of the protective sheet 28 is larger than the outer shape of the adhesive sheet 24, and the protective sheet 28 extends to the outside of the adhesive sheet 24. That is, the protective sheet 28 includes a portion that does not overlap the adhesive sheet 24.

  Of the two surfaces of the protective sheet 28, the surface facing the adhesive sheet 24 is the facing surface 28T, and the surface opposite to the facing surface 28T is the non-facing surface 28S. A part of the facing surface 28T of the protective sheet 28 is peeled off from the adhesive sheet 24 by a force that is generated when the user of the transdermal administration device 20 picks and pulls the protective sheet 28 with a finger. Can be attached to the adhesive surface 24S of the adhesive sheet 24.

  The shape of the protective sheet 28 viewed from the direction facing the first surface 22S is not particularly limited, and the protective sheet 28 may be circular or elliptical, may be rectangular, or these You may have a shape different from a shape. In the example shown as the first embodiment, the shape of the protective sheet 28 viewed from the direction facing the first surface 22S is a substantially rectangular shape, and the four corners of the protective sheet 28 are rounded so as to have a curvature. The outer edge of the protective sheet 28 is formed of a curve at the corner.

  The protective sheet 28 has an opening 29 at the center thereof that is approximately the same size as or slightly larger than the base 22 of the microneedle 21, and the microneedle 21 is located in the opening 29. The protective sheet 28 may have a notch or the like that can be used as a starting point of peeling when the user peels the protective sheet 28 from the adhesive sheet 24.

  The transdermal administration device 20 directs the first surface 22S of the base 22 and the non-opposing surface 28S of the protective sheet 28 of the microneedle 21 toward the first main body 40 of the housing unit 30, and the non-adhesive surface 24T of the adhesive sheet 24 and The protective sheet 28 is accommodated in the accommodating portion 30 with the facing surface 28 </ b> T facing the second main body portion 50 of the accommodating portion 30.

[Composition of housing part]
With reference to FIGS. 3-6, the detailed structure of the accommodating part 30 is demonstrated.
As shown in FIG. 3, when viewed from the reference direction, the first main body portion 40 has a substantially rectangular shape, and a first annular plate portion 41 positioned on the outermost portion of the first main body portion 40 and the first annular plate. A first annular convex portion 42 projecting from the portion 41, a first support plate portion 43 located inside the first annular convex portion 42, and an accommodating concave portion 44 that is recessed at the center of the first support plate portion 43. I have. Each of these parts is composed of a plate-like member having a substantially uniform thickness. When the first main body part 40 is viewed from the direction opposite to the reference direction, the convex part becomes a concave part, and the concave part has a convex part. It has become.

  When viewed from the reference direction, the first annular plate portion 41 has a substantially rectangular annular shape, and has a shape in which two relatively short belt-like portions and two relatively long belt-like portions are connected in an annular shape. . The connecting portions of these band-shaped portions are corner portions of the first annular plate portion 41, and three of the four corner portions have a shape having a curvature, and the outer peripheral edge and the inner peripheral edge thereof. Is composed of curves. The remaining one corner has a shape lacking so that the end is cut obliquely with respect to the band-shaped portion, compared to the other three corners. The corner having a shape different from that of the other corner is the starting point 45, and the width of the first annular plate 41 in the direction orthogonal to the circumferential direction is narrower than the other corners. .

  The first annular convex portion 42 is located inside the first annular plate portion 41 when viewed from the reference direction, has a substantially rectangular annular shape along the first annular plate portion 41, and stands from the first annular plate portion 41. The first side plate portion 46 is provided and extends, and the first upper plate portion 47 extends in parallel with the first annular plate portion 41 from the first side plate portion 46 toward the inside of the first annular plate portion 41. . When viewed from the reference direction, the four corners of the first annular convex portion 42 are rounded so as to have a curvature, and the outer peripheral edge and the inner peripheral edge are formed of curves. The first side plate portion 46 may extend in a direction orthogonal to the first annular plate portion 41, and in a direction inclined from this direction, for example, the first side plate portion 46 and the first annular plate portion 41. It extends so that the tip end portion connected to the first upper plate portion 47 in the first side plate portion 46 is positioned more inside the first annular plate portion 41 when viewed from the reference direction than the base portion to be connected. It may be.

  The first support plate portion 43 has a substantially rectangular shape when viewed from the reference direction, and extends in parallel with the first annular plate portion 41. When viewed from the reference direction, the four corner portions of the first support plate portion 43 are rounded so as to have a curvature, and the outer edges thereof are constituted by curves. The outer shape of the first support plate portion 43 matches the outer shape of the protective sheet 28 in the transdermal administration device 20 or is slightly larger than the outer shape of the protective sheet 28.

  The housing recess 44 has an elliptical shape when viewed from the reference direction. The outer shape of the housing recess 44 is larger than the outer shape of the region where the protrusions 23 are arranged in the first surface 22S of the base 22 of the microneedle 21, and substantially matches the outer shape of the adhesive sheet 24, for example.

  When viewed from a direction orthogonal to the reference direction, that is, from a direction parallel to the first annular plate portion 41 and the first support plate portion 43, the height of the bottom portion of the housing recess 44 coincides with the height of the first annular plate portion 41. The height of the first support plate portion 43 is the height between the first annular plate portion 41 and the first upper plate portion 47 of the first annular convex portion 42. In other words, when viewed from the reference direction, the first upper plate portion 47 surrounds the first support plate portion 43 and is disposed at a position elevated from the first support plate portion 43.

  Between the first upper plate portion 47 and the first support plate portion 43 of the first annular convex portion 42, the first connection plate portion 48 constituting the first main body portion 40 is located. When viewed from the reference direction, the short side portion of the outer edge of the first support plate portion 43 is located on the inner side of the short side portion of the inner peripheral edge of the first upper plate portion 47, and the first connection plate portion 48 includes the first connection plate portion 48. It extends with an inclination with respect to the upper plate portion 47 and the first support plate portion 43, and connects the short side portion of the inner peripheral edge of the first upper plate portion 47 and the short side portion of the outer edge of the first support plate portion 43. Yes. When viewed from the reference direction, the position of the long side portion of the outer edge of the first support plate portion 43 substantially coincides with the position of the long side portion of the inner peripheral edge of the first upper plate portion 47, and the first connection plate portion 48 is Extending substantially perpendicular to the first upper plate portion 47 and the first support plate portion 43, the long side portion of the inner peripheral edge of the first upper plate portion 47 and the long side portion of the outer edge of the first support plate portion 43 Are connected.

  The first main body portion 40 includes a first raised portion 49 that rises from the first connection plate portion 48 at a portion in contact with the boundary between the first support plate portion 43 and the first connection plate portion 48. When viewed from the reference direction, the first raised portion 49 is located at each of a position in contact with one of the two short side portions constituting the outer edge of the first support plate portion 43 and a position in contact with the other of the short side portions. That is, the first main body 40 has two first raised portions 49. The first raised portion 49 has a semi-columnar shape extending along the boundary between the first support plate portion 43 and the first connection plate portion 48.

  When viewed from the reference direction, the second main body portion 50 has a substantially rectangular shape, and a second annular plate portion 51 located at the outermost part of the second main body portion 50 and a second protrusion protruding from the second annular plate portion 51. An annular convex portion 52; a second support plate portion 53 positioned inside the second annular convex portion 52; a second connection plate portion 58 that connects the second annular convex portion 52 and the second support plate portion 53; Two second raised portions 59. Each of these parts is composed of a plate-like member having a substantially uniform thickness. When the second main body part 50 is viewed from the direction opposite to the reference direction, the convex part becomes a concave part, and the concave part is a convex part. It has become.

  The second annular plate 51 is on the first annular plate 41, the second annular projection 52 is on the first annular projection 42, the second connection plate 58 is on the first connection plate 48, and the second raised portion 59. Are formed in positions and shapes that can be superimposed on the first raised portions 49, respectively.

  Specifically, when viewed from the reference direction, the second annular plate portion 51 has a substantially rectangular annular shape, and all four corners of the second annular plate portion 51 have a shape having a curvature. That is, unlike the first annular plate portion 41, the second annular plate portion 51 does not have the starting point portion 45.

  The second annular convex portion 52 has a substantially rectangular annular shape along the second annular plate portion 51 located inside the second annular plate portion 51 when viewed from the reference direction, and stands up from the second annular plate portion 51. The second side plate portion 56 is provided and extends, and the second upper plate portion 57 extends in parallel with the second annular plate portion 51 from the second side plate portion 56 toward the inside of the second annular plate portion 51. . When viewed from the reference direction, the four corner portions of the second annular convex portion 52 have a shape having a curvature. The second side plate portion 56 may extend in a direction orthogonal to the second annular plate portion 51 in accordance with the direction in which the first side plate portion 46 extends, or may extend in a direction inclined from this direction.

  The second support plate portion 53 has a substantially rectangular shape as viewed from the reference direction and extends in parallel with the second annular plate portion 51, and the four corner portions of the second support plate portion 53 have a curvature. It has a shape. The outer shape of the second support plate portion 53 substantially matches the outer shape of the first support plate portion 43. Unlike the first main body 40, the second main body 50 does not have the housing recess 44, and the central portion of the second support plate 53 is not recessed.

  When viewed from the reference direction, the short side portion of the outer edge of the second support plate portion 53 is located on the inner side of the short side portion of the inner peripheral edge of the second upper plate portion 57, and the second connection plate portion 58 includes the second connection plate portion 58. It extends with an inclination with respect to the upper plate portion 57 and the second support plate portion 53, and connects the short side portion of the inner peripheral edge of the second upper plate portion 57 and the short side portion of the outer edge of the second support plate portion 53. Yes. When viewed from the reference direction, the position of the long side portion of the outer edge of the second support plate portion 53 substantially coincides with the position of the long side portion of the inner peripheral edge of the second upper plate portion 57, and the second connection plate portion 58 is Extending substantially perpendicular to the second upper plate portion 57 and the second support plate portion 53, the long side portion of the inner peripheral edge of the second upper plate portion 57 and the long side portion of the outer edge of the second support plate portion 53 Are connected.

  The second raised portion 59 is disposed at a position across the boundary between the second support plate portion 53 and the second connection plate portion 58, and rises from the second support plate portion 53 and the second connection plate portion 58. When viewed from the reference direction, a position straddling the boundary between one of the two short side portions constituting the outer edge of the second support plate portion 53 and the second connection plate portion 58, and the other of the short side portions and the second connection plate The second raised portion 59 is located at each position across the boundary with the portion 58. The second raised portion 59 has a shape formed of a part of a column extending along the boundary between the second support plate portion 53 and the second connection plate portion 58.

  As shown in FIGS. 4 to 6, when the transdermal administration device 20 is accommodated, the second main body 50 is the first main body 40, the second main body 50 is the upper layer when viewed from the reference direction, and the first main body 40 is It is piled up so that it may become a lower layer. Specifically, the first annular convex portion is formed on the second annular convex portion 52 such that the second side plate portion 56 of the second annular convex portion 52 is positioned outside the first side plate portion 46 of the first annular convex portion 42. 42 is fitted. As a result, the first main body portion 40 and the second main body portion 50 are releasably fitted by the force of a human hand, and the relative position of the first main body portion 40 to the second main body portion 50 is fixed. .

  As shown in FIG. 6, in a state where the first main body portion 40 and the second main body portion 50 are fitted, the first annular plate portion 41 is in contact with the second annular plate portion 51, and the first side plate portion 46 is the second one. The first upper plate portion 47 is in contact with the second upper plate portion 57, the first connection plate portion 48 is in contact with the second connection plate portion 58, and the first raised portion 49 is in contact with the second raised portion 59. Touch. The transdermal administration device 20 is accommodated in the space between the first support plate portion 43 and the accommodating recess 44 and the second support plate portion 53. In the cross section along the reference direction, the position of each part in the reference direction is such that the position of the bottom of the housing recess 44 coincides with the position of the first annular plate portion 41, and the first support plate portion 43 is connected to the first annular plate portion 41. The second support plate portion 53 is positioned between the first support plate portion 43 and the first upper plate portion 47, and is positioned between the first annular plate portion 42 and the first upper plate portion 47.

  When viewed from the reference direction, the outer edge of the first main body portion 40 and the outer edge of the second main body portion 50 coincide with each other at a portion other than the starting point portion 45 of the first main body portion 40. That is, in the portion other than the starting point portion 45, the second annular plate portion 51 overlaps the first annular plate portion 41, whereas in the corner portion where the starting point portion 45 is located, the second annular plate portion 51 includes A portion not overlapping with the first annular plate portion 41 is included.

[Detailed structure of transdermal administration device container]
A detailed configuration of the transdermal administration device housing 10 will be described with reference to FIG. FIG. 7 is an enlarged end view schematically showing a part of the transdermal administration device container 10 in a state where the transdermal administration device 20 is accommodated in the accommodation unit 30.

  As shown in FIG. 7, the first main body portion 40 faces the first surface 22S of the base 22 and the non-facing surface 28S of the protective sheet 28 in the microneedle 21. That is, the first main body 40 faces the tip of the protrusion 23. The second main body 50 faces the non-adhesive surface 24T of the adhesive sheet 24 and the opposing surface 28T of the protective sheet 28. That is, the second main body portion 50 faces the second surface 22T of the base 22 of the microneedle 21 with the adhesive sheet 24 interposed therebetween.

  In the transdermal administration device 20, the non-facing surface 28 </ b> S of the protective sheet 28 is supported by the first support plate portion 43 of the first main body 40, and the tip of the projection 23 of the microneedle 21 faces the bottom surface of the housing recess 44. As described above, it is disposed on the first main body 40. When viewed from the reference direction, the transdermal administration device 20 is sandwiched between two first raised portions 49. The transdermal administration device 20 and the first main body 40 are covered with the second main body 50.

  The length of the gap between the first support plate portion 43 and the second support plate portion 53 along the thickness direction of the base body 22, that is, the reference direction, is the accommodation length L1. Further, the total length of the thickness of the pressure-sensitive adhesive sheet 24 and the thickness of the protective sheet 28, that is, the length of the pressure-sensitive adhesive sheet 24 and the protective sheet 28 in the thickness direction of the substrate 22 is the sheet thickness L2. The accommodation length L1 is preferably equal to or less than the sheet thickness L2. If the accommodation length L1 is equal to or less than the sheet thickness L2, the adhesive sheet 24 and the protective sheet 28 are sandwiched between the first support plate portion 43 and the second support plate portion 53, and these sheets are supported by the first support plate portion 43 and the second support plate portion 53. Since it is pressed by the plate part 43 and the second support plate part 53, the position of the transdermal administration device 20 inside the housing part 30 is stabilized.

  In such a configuration, the non-adhesive surface 24T of the adhesive sheet 24 is in contact with the second support plate portion 53, the non-facing surface 28S of the protective sheet 28 is in contact with the first support plate portion 43, and the microneedle 21 includes the protective sheet 28. A portion protruding from the opening 29 is located in the accommodation recess 44. That is, the protrusion 23 is mainly located in the housing recess 44.

  The accommodation length L1 may be larger than the sheet thickness L2, that is, the non-adhesive surface of the adhesive sheet 24 in a state where the first main body 40 is disposed below the transdermal administration device 20. There may be a gap between the 24T and the second support plate portion 53.

[Action of transdermal device container]
Together with the operation of the transdermal administration device container 10 of the first embodiment, a procedure for taking out the transdermal administration device 20 from the accommodation unit 30 and administering a drug using the microneedle 21 will be described.

  As described above, when the first annular protrusion 42 is fitted to the second annular protrusion 52, the second body portion 40 of the first main body 40 is in the state in which the transdermal administration device 20 is accommodated in the accommodation part 30. The relative position with respect to the main body 50 is fixed. In other words, the body pair composed of the first body portion 40 and the second body portion 50 is percutaneous as viewed from the reference direction and the direction facing the first surface 22S of the base 22 of the microneedle 21. A fixing structure for fixing a relative position of the first main body 40 to the second main body 50 is provided outside the administration device 20. Accordingly, the positions of the first main body portion 40 and the second main body portion 50 are accurately fixed to each other. Therefore, even when the transdermal administration device housing 10 is transported, the first main body portion is caused by vibrations or the like generated during transport. It is suppressed that the position of 40 with respect to the second main body portion 50 is shifted and the housing portion 30 is unsealed. Therefore, according to the above configuration, the protective function of the transdermal administration device 20 by the housing unit 30 is enhanced.

  In addition, since such a fixing structure is located in an annular shape surrounding the transdermal administration device 20 when viewed from the reference direction, the positions of the first main body 40 and the second main body 50 are more firmly fixed.

  When the transdermal administration device 20 is taken out from the storage unit 30, the user of the transdermal administration device 20 percutaneously places the first main body 40 under the transdermal administration device 20 as viewed from the user. The administration device container 10 is arranged, the second main body 50 is pulled up, and the second main body 50 is removed from the first main body 40. That is, the second annular convex portion 52 is removed from the first annular convex portion 42, the fitting between the first main body portion 40 and the second main body portion 50 is released, and the first main body portion 40 and the second main body portion 50 are released. The space between is open to the outside. At this time, since the second annular plate portion 51 includes a portion that does not overlap the first annular plate portion 41 in the corner portion where the starting point portion 45 of the first main body portion 40 is located, the user can The first main body 40 and the second main body 50 can be easily separated by picking a portion of the annular plate 51 that does not overlap the first annular plate 41 and pulling up the second main body 50. .

  By removing the second main body portion 50 from the first main body portion 40, the housing portion 30 is opened, and the user can contact the non-adhesive surface 24T of the adhesive sheet 24 and the opposing surface of the protective sheet 28 in the transdermal administration device 20. 28T becomes visible. The user picks up the end portion of the protective sheet 28 and picks up the transdermal administration device 20 from the first main body portion 40 to take out the transdermal administration device 20 from the housing portion 30.

  At this time, in the first main body portion 40, the first connection plate portion 48 extends while being inclined with respect to the first upper plate portion 47 and the first support plate portion 43, and the first upper plate portion 47 and the first support portion. Since the plate portion 43 is connected, the portion supporting the transdermal administration device 20 in the first main body portion 40 and the portion protruding around the portion are gently connected. Therefore, the user percutaneously administers the transdermal administration device 20 along the inclined portion of the first connecting plate 48 or slides the finger under the transdermal administration device 20 along the inclined portion. The transdermal administration device 20 can be taken out by picking the device 20 or the like. Therefore, the transdermal administration device 20 can be easily taken out from the storage unit 30.

  On the other hand, in the state where the transdermal administration device 20 is accommodated in the accommodating portion 30, the transdermal administration device is sandwiched between the two first raised portions 49 that rise from the inclined portion of the first connection plate portion 48. When the second main body 50 is removed from the first main body 40, the position of the transdermal administration device 20 is prevented from moving in the direction along the first surface 22S of the base body 22. Therefore, the transdermal administration device 20 can be prevented from sliding off from the first main body portion 40 when the container 30 is opened, while the structure allows easy removal of the transdermal administration device 20.

  The first main body portion 40 is provided with a first raised portion 49, and the second main body portion 50 is provided with a second raised portion 59 that overlaps the first raised portion 49. When the two main body portions 50 are assembled, the first main body portion 40 and the second main body portion 50 can be easily aligned using these raised portions 49 and 59.

  After removing the transdermal administration device 20, the user peels the protective sheet 28 from the adhesive sheet 24, presses the first surface 22 </ b> S of the base 22 of the microneedle 21 against the skin at the site where the drug is administered, and the base 22 The adhesive surface 24S of the adhesive sheet 24 that protrudes outside is attached to the skin. Thereby, the protrusion 23 perforates the skin and the drug is administered.

  Note that when the container 30 is opened, the second main body 50 is disposed so that the second main body 50 is positioned below the transdermal administration device 20 when viewed from the user, and the first main body 40 is pulled up, whereby the second main body The first main body 40 may be removed from 50.

[Material for device for transdermal administration]
The material of the transdermal administration device housing 10 will be described.
The microneedle 21 is preferably formed from a biocompatible material. Examples of the material constituting the microneedles 21 include metals such as silicon, stainless steel, titanium, and manganese, and thermoplastic resins such as medical silicone, polylactic acid, polyglycolic acid, polycarbonate, and cyclic olefin copolymers. Is mentioned. Moreover, the microneedle 21 may be comprised from the material which melt | dissolves with the water | moisture content which skin has, ie, a water-soluble material. As the water-soluble material, water-soluble polymers and polysaccharides can be used. Examples of water-soluble polymers include carboxymethylcellulose (CMC), methylcellulose (MC), hydroxypropylcellulose (HPC), hydroxypropylmethylcellulose (HPMC), polyvinyl alcohol (PVA), polyacrylic acid polymer, polyacrylamide (PAM), Examples include polyethylene oxide (PEO), pullulan, alginate, pectin, chitosan, chitosan succinamide, and oligochitosan. Among the above materials, chitosan, chitosan succinamide, carboxymethylcellulose (CMC), hydroxypropylcellulose (HPC), and hydroxypropylmethylcellulose (HPMC) are preferably used because they are biologically safe. it can. Examples of polysaccharides include trehalose and maltose. The protrusion 23 formed of the water-soluble material is dissolved in the skin after being stabbed into the skin.
In addition, the base | substrate 22 and the projection part 23 may be formed from the mutually same material, and may be formed from a mutually different material.

  The drug to be administered by the microneedle 21 is attached to the surface of the protrusion 23, and may be sent into the skin together with the formation of the hole by the protrusion 23, or the protrusion 23 has a solubility as described above. In the case where the protrusion 23 is formed, it may be included in the protrusion 23 and fed into the skin together with the dissolution of the protrusion 23. Alternatively, when a groove or hole is formed in the protrusion 23, the groove or hole may be filled with a drug, and the drug may be fed into the skin along with the formation of a hole in the skin by the protrusion 23. Good. Alternatively, before or after the protrusion 23 is stabbed into the skin, a liquid medicine may be applied to the skin, and the medicine may be sent into the skin from a hole formed by the protrusion 23. Furthermore, the drug may be administered in a form in which these methods are combined. In addition, when the projection part 23 is formed from the material which has solubility, the water-soluble material which comprises the projection part 23 may function as a chemical | medical agent.

  The type of drug is not particularly limited as long as it is a substance that functions by being administered intradermally. Examples of the drug include pharmacologically active substances and cosmetic compositions, and are selected according to the purpose.

  Examples of the pharmacologically active substance include vaccines such as influenza, analgesics for cancer patients, insulin, biologics, gene therapy drugs, injections, oral preparations, and preparations for skin application. In transdermal administration using the microneedle 21, a drug is administered into a hole formed in the skin. Therefore, transdermal administration using the microneedle 21 can be used for administration of pharmacologically active substances that require subcutaneous injection, in addition to the pharmacologically active substances used for conventional transdermal administration. In particular, transdermal administration using the microneedle 21 is suitable for administration of injections such as vaccines to children because it does not give pain to the patient during administration. In addition, transdermal administration using the microneedle 21 is suitable for administration of oral preparations for children who are difficult to take oral preparations because the patient does not need to take the medicine at the time of administration.

  A cosmetic composition is a composition used as a cosmetic or a cosmetic. Examples of the cosmetic composition include a moisturizer, a colorant, a fragrance, or a physiologically active substance that exhibits a beauty effect such as an improvement effect on wrinkles, acne, pregnancy lines, and an improvement effect on hair loss. When a fragrant material is used as the cosmetic composition, it is possible to impart an odor to the microneedles 21, so that the microneedles 21 suitable for cosmetics are obtained.

  Although the material of the adhesive sheet 24 is not particularly limited, examples of the base sheet 26 include polyolefin resins such as polyethylene and polypropylene, polyester resins such as nylon and polyethylene terephthalate, polyvinyl chloride, polyvinylidene chloride, or A resin sheet made of polyvinyl alcohol or the like is used. The adhesive layer 25 is formed of, for example, a silicone-based adhesive, a rubber-based adhesive, an epoxy-based adhesive, or an acrylic-based adhesive.

  The material of the protective sheet 28 is such that when the protective sheet 28 is peeled from the adhesive sheet 24, the adhesive sheet 24 has an adhesive force that can maintain the state where the adhesive sheet 24 is stuck to the administration target of the drug over a desired period. It is preferable that the non-biocompatible material remains on the adhesive surface 24S while being held. Specifically, as a material for the protective sheet 28, a sheet or paper made of a resin such as polyethylene terephthalate in which at least one surface is coated with a silicone release agent or a fluorine release agent can be used. The surface coated with the release agent is the facing surface 28T attached to the adhesive surface 24S of the adhesive sheet 24.

  The material of each of the first main body portion 40 and the second main body portion 50 constituting the housing portion 30 is not particularly limited. For example, a polyolefin resin such as polyethylene and polypropylene, a polyester resin such as nylon and polyethylene terephthalate, or An acrylic resin such as polystyrene is used. Each of the first main body portion 40 and the second main body portion 50 may be colorless and transparent, may be colored and transparent, or may be translucent or opaque.

  In the first embodiment, the first upper plate portion 47 is an example of the outer peripheral portion, the first support plate portion 43 is an example of the support plate portion, and the inclined portion in the first connection plate portion 48 is the inclined portion. The 1st main-body part 40 provided with these is an object main-body part. Moreover, the 1st support plate part 43 is an example of a 1st opposing part, and the 2nd support plate part 53 is an example of a 2nd opposing part.

As described above, according to the transdermal administration device housing 10 of the first embodiment, the following effects can be obtained.
(1) The main body pair composed of the first main body portion 40 and the second main body portion 50 is located on the outer side of the transdermal administration device 20 with respect to the second main body portion 50 of the first main body portion 40 when viewed from the reference direction. A fixing structure for releasably fixing the relative position is provided. Accordingly, the positions of the first main body portion 40 and the second main body portion 50 are accurately fixed to each other. Therefore, even when the transdermal administration device housing 10 is transported, the first main body portion is caused by vibrations or the like generated during transport. It is suppressed that the position of 40 with respect to the second main body portion 50 is shifted and the housing portion 30 is unsealed. Therefore, the protection function of the transdermal administration device 20 by the accommodating part 30 is enhanced.

  (2) The fixing structure is a fitting structure, and the accommodating portion 30 can open the space between the first main body portion 40 and the second main body portion 50 to the outside by releasing the fitting in the fitting structure. It is configured. According to such a configuration, it is easier to open the housing portion 30 as compared to a structure in which the first main body portion 40 and the second main body portion 50 are fixed to each other by bonding or the like.

  (3) Since the fitting structure is located in an annular shape surrounding the transdermal administration device 20 when viewed from the reference direction, the relative position of the first main body 40 with respect to the second main body 50 is more fixed. Become strong.

  (4) When viewed from the reference direction, the second annular plate portion 51 includes a portion that does not overlap the first annular plate portion 41 at the end portion of the corner portion where the starting point portion 45 of the first main body portion 40 is located. Therefore, the user can easily lift the first main body portion 40 and the second main body portion by picking up a portion of the second annular plate portion 51 that does not overlap the first annular plate portion 41 and pulling up the second main body portion 50. 50 can be separated. Therefore, opening of the accommodating part 30 is easy.

  (5) The first connection plate portion 48 extends with an inclination with respect to the first support plate portion 43, and a part of the outer edge of the first support plate portion 43 and a portion of the inner peripheral edge of the first upper plate portion 47. Are connected. That is, the part which supports the transdermal administration device 20 in the 1st main-body part 40 and the part which protrudes in the circumference | surroundings are connected gently. Therefore, the user percutaneously administers the transdermal administration device 20 along the inclined portion of the first connecting plate 48 or slides the finger under the transdermal administration device 20 along the inclined portion. The transdermal administration device 20 can be taken out by picking the device 20 or the like. Therefore, the transdermal administration device 20 can be easily taken out from the storage unit 30.

  (6) In the state where the transdermal administration device 20 is accommodated in the accommodation portion 30, the transdermal administration device 20 is sandwiched between the two first raised portions 49 when viewed from the reference direction. When the second main body portion 50 is removed from the portion 40, the position of the transdermal administration device 20 is suppressed from moving in the direction along the first surface 22S of the base body 22. Therefore, the transdermal administration device 20 can be prevented from sliding off from the first main body portion 40 when the container 30 is opened, while the structure allows easy removal of the transdermal administration device 20.

  (7) In the reference direction, the length between the first support plate portion 43 that faces the non-facing surface 28S of the protective sheet 28 and the second support plate portion 53 that faces the non-stick surface 24T of the adhesive sheet 24. A certain accommodation length L1 is equal to or less than the sheet thickness L2, which is the total length of the thickness of the adhesive sheet 24 and the thickness of the protective sheet 28. According to such a configuration, the adhesive sheet 24 and the protective sheet 28 are sandwiched between the first support plate portion 43 and the second support plate portion 53, and these sheets serve as the first support plate portion 43 and the second support plate. Since it is pressed by the plate portion 53, the position of the transdermal administration device 20 inside the accommodating portion 30 is stabilized.

[Modification of First Embodiment]
The first embodiment may be implemented with the following modifications.
-The external shape of the 1st main-body part 40 and the 2nd main-body part 50 seen from the reference | standard direction may differ from the said embodiment. For example, the outer shape of the first main body portion 40 and the second main body portion 50 may be a rectangular shape with corners formed at right angles, or may be a circular shape or an elliptical shape. That is, the outer shape of the first annular plate portion 41 and the first annular convex portion 42, the second annular plate portion 51 and the second annular convex portion 52 may be a rectangular annular shape with corners formed at right angles, An annular or elliptical ring may be used. Further, the outer shape of the first support plate portion 43 and the second support plate portion 53 may be a rectangular shape with corners formed at right angles, or may be a circular shape or an elliptical shape. Further, the outer shape of the housing recess 44 is not limited to an elliptical shape. The shape of each part may be determined according to the shape of each part of the transdermal administration device 20 accommodated in the accommodating part 30.

  When viewed from the reference direction, the outer edges of the support plate portions 43 and 53 are located on the inner side of the inner peripheral edge of the upper plate portions 47 and 57 over the entire circumference, and the connection plate portions 48 and 58 are entirely formed. The upper plate portions 47 and 57 and the support plate portions 43 and 53 may be inclined to extend so as to connect the entire outer edges of the support plate portions 43 and 53 and the inner peripheral edges of the upper plate portions 47 and 57. Further, when viewed from the reference direction, the outer edges of the support plate portions 43 and 53 coincide with the inner peripheral edges of the upper plate portions 47 and 57 over the entire circumference, and the connection plate portions 48 and 58 are entirely formed of the upper plate. It extends perpendicularly to the portions 47 and 57 and the support plate portions 43 and 53, and may connect the entire outer edge of the support plate portions 43 and 53 and the inner peripheral edge of the upper plate portions 47 and 57.

  In the above embodiment, the first main body 40 has the starting point 45 and the end of the second main body 50 has a portion that does not overlap the first main body 40, but the second main body 50 starts. A portion 45 may be provided, and the end of the first main body 40 may be provided with a portion that does not overlap the second main body 50. Further, the end portion of the second main body portion 50 may include a portion that does not overlap the first main body portion 40, and the end portion of the first main body portion 40 may include a portion that does not overlap the second main body portion 50. Even with such a configuration, the effect according to the above (4) can be obtained. In addition, about the 2nd main-body part 50 which is a main-body part pulled up at the time of opening of the accommodating part 30, the direction of the structure provided with the part which the edge part does not overlap with the 1st main-body part 40 is a 2nd main-body part. Easy to pull 50.

  The position of each part of the housing part 30 as viewed from the direction orthogonal to the reference direction may be different from the above embodiment. For example, the position of the bottom part of the housing recess 44 does not coincide with the position of the first annular plate part 41. May be.

  -The shape of the 1st protruding part 49 is not restricted to the shape of the said embodiment, What is necessary is just to swell from the 1st connection board part 48, and the shape of the 2nd protruding part 59 is according to the shape of the 1st protruding part 49. Any shape can be used. Further, the number of sets of the first raised portions 49 and the second raised portions 59 may be three or more.

(Second Embodiment)
A second embodiment of the transdermal administration device container will be described with reference to FIGS. The transdermal administration device housing of the second embodiment is different from the first embodiment in the structure for fitting the first main body and the second main body. Below, it demonstrates centering on difference with 1st Embodiment, about the structure similar to 1st Embodiment, the same code | symbol is attached | subjected and the description is abbreviate | omitted.

[Composition of housing part]
With reference to FIG. 8 and FIG. 9, the detailed structure of the accommodating part 30 with which the transdermal administration device accommodating body 15 of 2nd Embodiment is provided is demonstrated.
As shown in FIG. 8, the accommodating portion 30 is composed of a first main body portion 60 and a second main body portion 70. The first main body portion 60 faces the first surface 22S of the base 22 and the non-facing surface 28S of the protective sheet 28 in the microneedle 21, and the second main body portion 70 is the non-adhesive surface 24T of the pressure-sensitive adhesive sheet 24 and the protective sheet 28. Opposite to the opposing surface 28T.

  In the description of the second embodiment, the reference direction is a direction along the direction in which the first main body 60 and the second main body 70 are overlapped, as in the first embodiment. Among them, it is a direction facing a portion directed to the outside of the accommodating portion 30 and a direction facing a portion directed to the inside of the accommodating portion 30 in the first main body portion 60.

  As shown in FIG. 9, when viewed from the reference direction, the first main body portion 60 has a substantially rectangular shape, and a first annular plate portion 61 positioned on the outermost portion of the first main body portion 60 and the first annular plate. A first belt-like recess 62 that is recessed from the portion 61, a first support plate portion 43 that is positioned inside the first annular plate portion 61, an accommodation recess 44, a first connection plate portion 48, and a first raised portion 49. It has. Each of these parts is composed of a plate-like member having a substantially uniform thickness. When the first main body part 60 is viewed from the direction opposite to the reference direction, the convex part becomes a concave part, and the concave part has a convex part. It has become.

  When viewed from the reference direction, the first annular plate portion 61 has a substantially rectangular annular shape, and the four corners of the first annular plate portion 61 have curvatures whose inner and outer peripheral edges are configured by curves. It has the shape to have. In addition, the 1st annular board part 61 may have the starting part similar to the starting part 45 of 1st Embodiment.

  The first strip-shaped recess 62 is a recess that is recessed in a relatively long strip-shaped portion of the strip-shaped portion constituting the first annular plate portion 61. The first band-shaped recess 62 is located in each of the two long band-shaped portions in the first annular plate section 61, that is, the first main body 60 has two first band-shaped recesses 62. When viewed from the reference direction, the first band-shaped recess 62 has an oval shape extending along the first annular plate portion 61. When viewed from the reference direction, one of the two first band-shaped recesses 62 is a part close to one of the two relatively short band-shaped parts constituting the first annular plate part 61 in the long band-shaped part. The other one of the two first belt-like recesses 62 is located in a portion close to the other of the two short belt-like portions in the long belt-like portion.

  When viewed from a direction orthogonal to the reference direction, that is, a direction parallel to the first annular plate portion 61 and the first support plate portion 43, the first band-shaped recess 62 is formed from the first annular plate portion 61 to the first annular plate portion. It protrudes in the same direction as the direction in which the first support plate 43 is located with respect to 61.

  Each of the 1st support plate part 43 and the accommodation recessed part 44 has the structure similar to 1st Embodiment. The 1st connection board part 48 has the structure similar to 1st Embodiment except the members connected are different. That is, when viewed from the reference direction, the first annular plate portion 61 surrounds the support plate portion 43 and is disposed at a position rising from the support plate portion 43, and the first connection plate portion 48 is the first annular plate portion. 61 and the first support plate portion 43 are inclined and extend to connect the short side portion of the inner peripheral edge of the first annular plate portion 61 and the short side portion of the outer edge of the first support plate portion 43. Further, the first connection plate portion 48 extends substantially perpendicular to the first annular plate portion 61 and the first support plate portion 43, and the long side portion of the inner peripheral edge of the first annular plate portion 61 and the first support plate The long side part of the outer edge of the part 43 is connected. Moreover, the 1st protruding part 49 has the structure similar to 1st Embodiment.

  When viewed from the reference direction, the second main body portion 70 has a substantially rectangular shape, and a second annular plate portion 71 located at the outermost part of the second main body portion 70 and a second recess recessed from the second annular plate portion 71. A band-shaped recess 72, a second support plate portion 53 positioned inside the second annular plate portion 71, a second connection plate portion 58, and a second raised portion 59 are provided. Each of these parts is composed of a plate-like member having a substantially uniform thickness. When the second main body part 70 is viewed from a direction opposite to the reference direction, the convex part becomes a concave part, and the concave part is a convex part. It has become.

The second annular plate portion 71 is the first annular plate portion 61, the second strip-shaped recess 72 is the first strip-shaped recess 62, the second connection plate portion 58 is the first connection plate portion 48, and the second raised portion 59 is the first. Each bulge 49 is formed in a position and shape that can be overlapped.
Specifically, when viewed from the reference direction, the second annular plate portion 71 has a substantially rectangular annular shape, and the four corner portions of the second annular plate portion 71 have a shape having a curvature.

  The second strip-shaped recess 72 is a recess that is recessed in a relatively long strip-shaped portion among the strip-shaped portions constituting the second annular plate portion 71, and each of the two long strip-shaped portions in the second annular plate portion 71. In addition, the second band-shaped recess 72 is located. When viewed from the reference direction, the second band-shaped recess 72 has an oval shape extending along the second annular plate portion 71. When viewed from the reference direction, one of the two second belt-like recesses 72 is a portion close to one of the two relatively short belt-like portions constituting the second annular plate portion 71 in the long belt-like portion. The other of the two second strip-shaped recesses 72 is located in a portion close to the other of the two short strip-shaped portions in the long strip-shaped portion.

  When viewed from the direction orthogonal to the reference direction, that is, the direction parallel to the second annular plate portion 71 and the second support plate portion 53, the second band-shaped recess 72 is formed from the second annular plate portion 71 to the second annular plate portion. 71 protrudes in the same direction as the direction in which the second support plate portion 53 is located. That is, the second belt-like recess 72 protrudes from the second annular plate portion 71 toward the first main body portion 60.

  The second support plate portion 53 has the same configuration as that of the first embodiment, and the second connection plate portion 58 has the same configuration as that of the first embodiment except that connected members are different. Have. That is, the second connection plate portion 58 extends while being inclined with respect to the second annular plate portion 71 and the second support plate portion 53, and the short side portion of the inner peripheral edge of the second annular plate portion 71 and the second support plate. The short side part of the outer edge of the part 53 is connected. Further, the second connection plate portion 58 extends substantially perpendicular to the second annular plate portion 71 and the second support plate portion 53, and the long side portion of the inner peripheral edge of the second annular plate portion 71 and the second support plate. The long side part of the outer edge of the part 53 is connected. Moreover, the 2nd protruding part 59 has the structure similar to 1st Embodiment.

  As shown in FIGS. 10 to 13, when the transdermal administration device 20 is accommodated, the second main body portion 70 is placed on the first main body portion 60, the second main body portion 70 is the upper layer, and the first main body portion 60 is seen from the reference direction. It is piled up so that it may become a lower layer. Specifically, the second belt-like recess 72 is fitted into the first belt-like recess 62 so that the second belt-like recess 72 is located inside the first belt-like recess 62, whereby the first main body portion 60 and the second main body portion 70 are fitted. The relative position of the first main body 60 with respect to the second main body 70 is releasably fixed.

  As shown in FIGS. 12 and 13, in a state where the first main body portion 60 and the second main body portion 70 are fitted, the first annular plate portion 61 is in contact with the second annular plate portion 71 and the first belt-like recess 62. Is in contact with the second band-shaped recess 72, the first connection plate portion 48 is in contact with the second connection plate portion 58, and the first raised portion 49 is in contact with the second raised portion 59. The transdermal administration device 20 is accommodated in the space between the first support plate portion 43 and the accommodating recess 44 and the second support plate portion 53.

In the cross section along the reference direction, the position of each part in the reference direction is such that the position of the bottom of the housing recess 44 coincides with the position of the bottom of the first belt-shaped recess 62, and the first support plate 43 is formed of the first belt-shaped recess 62. The second support plate 53 is located between the bottom and the first annular plate 61, and the second support plate 53 is located between the first support plate 43 and the first annular plate 61.
[Detailed structure of transdermal administration device container]
FIG. 14 is an end view schematically showing an enlarged part of the transdermal administration device housing 15 in a state where the transdermal administration device 20 is accommodated in the accommodation portion 30.

  In the state accommodated in the accommodating part 30, the positional relationship between the transdermal administration device 20, the first main body part 60, and the second main body part 70 is the same as in the first embodiment. That is, in the transdermal administration device 20, the non-facing surface 28 </ b> S of the protective sheet 28 is supported by the first support plate portion 43 of the first main body portion 60, and the tip of the projection 23 of the microneedle 21 is in contact with the bottom surface of the housing recess 44. It arrange | positions on the 1st main-body part 60 so that it may oppose. When viewed from the reference direction, the transdermal administration device 20 is sandwiched between two first raised portions 49. The transdermal administration device 20 and the first main body 60 are covered with the second main body 70. Also in the second embodiment, the accommodation length L1 is preferably not more than the sheet thickness L2.

[Action of transdermal device container]
Together with the operation of the transdermal administration device container 15 of the second embodiment, a procedure for taking out the transdermal administration device 20 from the accommodation unit 30 and administering the drug using the microneedle 21 will be described.

  As described above, the second main body portion of the first main body portion 60 in the state in which the transdermal administration device 20 is accommodated in the accommodating portion 30 by fitting the second band-shaped concave portion 72 to the first belt-shaped concave portion 62. The relative position with respect to 70 is fixed. That is, also in the second embodiment, the main body pair composed of the first main body portion 60 and the second main body portion 70 is from each of the reference direction and the direction facing the first surface 22S of the base 22 of the microneedle 21. As seen, a fixing structure for fixing the relative position of the first main body portion 60 to the second main body portion 70 is provided outside the transdermal administration device 20. Therefore, since the position with respect to each other of the first main body portion 60 and the second main body portion 70 is accurately fixed, the protective function of the transdermal administration device 20 by the housing portion 30 is enhanced.

  In addition, since a plurality of, specifically two, such fixing structures are arranged outside the transdermal administration device 20 when viewed from the reference direction, the fixing structure is provided only at one place. The position of the first main body 60 relative to the second main body 70 is more firmly fixed. When the first embodiment is compared with the second embodiment, the first main body 40 and the second main body 50 are fixed when the fixing structure has an annular shape as in the first embodiment. Become strong. On the other hand, as in the second embodiment, it is easier to open the accommodating portion 30 when a plurality of separated fixing structures are provided.

  When the transdermal administration device 20 is taken out from the container 30, the user of the transdermal administration device 20 uses the first main body 60 of the transdermal administration device 20 as viewed from the user, as in the first embodiment. The transdermal administration device container 15 is disposed so as to be positioned below, the second main body portion 70 is pulled up, and the second main body portion 70 is removed from the first main body portion 60. That is, the second band-shaped recess 72 is removed from the first band-shaped recess 62, and the fitting between the first main body 60 and the second main body 70 is released.

  By removing the second main body portion 70 from the first main body portion 60, the accommodating portion 30 is opened, and the space between the first main body portion 60 and the second main body portion 70 is opened to the outside. As a result, the user can see the non-adhesive surface 24T of the adhesive sheet 24 and the opposing surface 28T of the protective sheet 28 in the transdermal administration device 20. The user picks up the end portion of the protective sheet 28 and picks up the transdermal administration device 20 from the first main body 60, thereby taking out the transdermal administration device 20 from the storage unit 30. Thereafter, the user peels off the protective sheet 28 from the adhesive sheet 24, presses the first surface 22 </ b> S of the base 22 of the microneedle 21 against the skin of the site where the drug is administered, and the adhesive sheet 24 protrudes outside the base 22. The adhesive surface 24S is affixed to the skin. Thereby, the protrusion 23 perforates the skin and the drug is administered.

  In addition, when opening the accommodating portion 30, the second main body portion 70 is disposed so that the second main body portion 70 is positioned below the transdermal administration device 20 when viewed from the user, and the first main body portion 60 is pulled up, whereby the second main body portion. The first main body 60 may be removed from 70.

  In the second embodiment, the first annular plate portion 61 is an example of an outer peripheral portion, the first support plate portion 43 is an example of a support plate portion, and the inclined portion in the first connection plate portion 48 is an example of an inclined portion. The first main body 60 including these is the target main body. Moreover, the 1st support plate part 43 is an example of a 1st opposing part, and the 2nd support plate part 53 is an example of a 2nd opposing part.

  As described above, according to the transdermal administration device housing 15 of the second embodiment, in addition to (1), (2), (5) to (7) of the first embodiment, the following effects are obtained. can get.

  (8) Since the main body pair composed of the first main body portion 60 and the second main body portion 70 has a plurality of fitting structures outside the transdermal administration device 20 when viewed from the reference direction. Compared with the configuration in which the fixing structure is provided only at one place, the fixing of the positions of the first main body portion 60 and the second main body portion 70 with respect to each other becomes stronger.

[Modification of Second Embodiment]
The second embodiment may be implemented with the following modifications.
As in the modification of the first embodiment, the outer shapes of the first main body portion 60 and the second main body portion 70 viewed from the reference direction may be different from those of the above-described embodiment. The formed rectangular shape may be a circular shape or an elliptical shape. That is, the outer shape of the first annular plate portion 61 and the second annular plate portion 71 may be a rectangular ring having corners formed at right angles, or may be an annular or elliptical ring.

  The position of each part of the housing part 30 as viewed from the direction orthogonal to the reference direction may be different from that of the above embodiment. For example, the position of the bottom part of the housing recess 44 coincides with the position of the bottom part of the first belt-like recess 62. It does not have to be. However, the position of the bottom of the housing recess 44 coincides with the position of the bottom of the first belt recess 62, or the bottom of the first belt recess 62 is closer to the second body 70 than the bottom of the housing recess 44. When the transdermal administration device container 15 is placed in an exterior bag, the first band-shaped recess 62 is less likely to be caught on the end of the bag, and the transdermal administration device container 15 can be easily put in and out. .

  The recesses for fitting the first main body part 60 and the second main body part 70, that is, the shapes and numbers of the first belt-like recesses 62 and the second belt-like recesses 72 may be different from those in the above embodiment. For example, the outer shape of these recesses viewed from the reference direction may be a circular shape or a polygonal shape, and the number of sets of these recesses may be three or more.

(Third embodiment)
With reference to FIGS. 15-23, 3rd Embodiment of a transdermal administration device container is described. The transdermal administration device housing of the third embodiment is mainly different from the first embodiment in the structure for fitting the first body portion and the second body portion and the structure for opening the housing portion. Below, it demonstrates centering on difference with 1st Embodiment, about the structure similar to 1st Embodiment, the same code | symbol is attached | subjected and the description is abbreviate | omitted.

[Composition of housing part]
With reference to FIG. 15, the detailed structure of the accommodating part 30 with which the transdermal administration device accommodating body 16 of 3rd Embodiment is provided is demonstrated.
As shown in FIG. 15, the accommodating portion 30 is composed of a first main body portion 80 and a second main body portion 90. The first main body 80 faces the first surface 22S of the base 22 and the non-facing surface 28S of the protective sheet 28 in the microneedle 21, and the second main body 90 is a non-adhesive surface 24T of the pressure-sensitive adhesive sheet 24 and the protective sheet 28. Opposite to the opposing surface 28T.

  In the description of the third embodiment, the reference direction is a direction along the direction in which the first main body portion 80 and the second main body portion 90 are overlapped, and in the first main body portion 80, outside the accommodating portion 30. It is a direction opposite to the part to be directed and a direction to face a part directed to the inside of the accommodating part 30 in the second main body 90.

  When viewed from the reference direction, the first main body portion 80 has a substantially rectangular shape, a main plate portion 81 that spreads in a plate shape, an accommodating convex portion 82 that protrudes from the main plate portion 81, a first fitting convex portion 83, and The first positioning convex portion 84 is provided with three convex portions. Each of these parts is composed of a plate-like member having a substantially uniform thickness. When the first main body part 80 is viewed from the direction opposite to the reference direction, the convex part becomes a concave part, and the concave part is a convex part. It has become.

  When viewed from the reference direction, the main plate portion 81 has a substantially rectangular shape, and the four corner portions of the main plate portion 81 have a shape having a curvature. When viewed from the reference direction, the accommodating convex portion 82 is located at the center of the main plate portion 81 and has an elliptical shape. The outer shape of the housing convex portion 82 is larger than the outer shape of the region where the protrusion 23 is arranged in the first surface 22S of the base 22 of the microneedle 21, and substantially matches the outer shape of the adhesive sheet 24, for example.

  As viewed from the reference direction, each of the first fitting convex portion 83 and the first positioning convex portion 84 has a circular shape. When viewed from the reference direction, the first fitting convex portion 83 is located in the vicinity of one corner portion of the main plate portion 81, and the first positioning convex portion 84 is located in the vicinity of the other corner portion of the main plate portion 81. These corner portions are located on the same diagonal line in the main plate portion 81. The first positioning convex portion 84 protrudes from the main plate portion 81 in a hemispherical shape.

  When viewed from the reference direction, the second main body portion 90 has a substantially rectangular shape, an annular plate portion 91 located at the outermost part of the second main body portion 90, an accommodation recess 95 and a connection recess recessed from the annular plate portion 91. 96 and a second fitting convex portion 93 and a second positioning convex portion 94 protruding from the annular plate portion 91. Each of these parts is composed of a plate-like member having a substantially uniform thickness. When the second main body part 90 is viewed from the direction opposite to the reference direction, the convex part becomes a concave part, and the concave part becomes a convex part. It has become.

  When viewed from the reference direction, the annular plate portion 91 has a substantially rectangular annular shape, and the four corners of the annular plate portion 91 have a shape with a curvature in which the inner peripheral edge and the outer peripheral edge are configured by curves. doing. When viewed from the reference direction, the housing recess 95 is located inside the annular plate portion 91 and has a substantially rectangular shape. When viewed from the reference direction, the four corners of the accommodation recess 95 have a curved shape, and the outer shape of the accommodation recess 95 matches the outer shape of the protection sheet 28 in the transdermal administration device 20 or the protection sheet 28. Slightly larger than the outer shape.

  When viewed from the reference direction, the connection recess 96 has a semicircular shape protruding from the short side portion of the housing recess 95 toward the annular plate 91. That is, when viewed from the reference direction, the inner peripheral edge of the annular plate portion 91 is curved toward the outer peripheral edge along the outer shape of the connection concave portion 96 at the portion where the connection concave portion 96 is located. The width in the orthogonal direction is narrowed.

  The bottom of the housing recess 95 is parallel to the annular plate portion 91 and extends in a direction perpendicular to the reference direction. When viewed from the reference direction, the annular plate portion 91 surrounds the bottom of the housing recess 95 and is disposed at a position rising from the bottom of the housing recess 95. The bottom portion of the connection recess 96 is inclined with respect to the annular plate portion 91 and the bottom portion of the accommodation recess 95, and connects the inner peripheral edge of the annular plate portion 91 and the short side portion of the bottom portion of the accommodation recess 95.

  As viewed from the reference direction, each of the second fitting convex portion 93 and the second positioning convex portion 94 has a circular shape. When viewed from the reference direction, the second fitting convex portion 93 is located near one corner of the annular plate portion 91, and the second positioning convex portion 94 is located near the other corner portion of the annular plate portion 91. These corner portions are located on the same diagonal line in the annular plate portion 91. The second positioning convex portion 94 protrudes from the annular plate portion 91 in a hemispherical shape.

  As shown in FIGS. 16 to 19, when the transdermal administration device 20 is accommodated, the first main body 80 is the second main body 90, the first main body 80 is the upper layer when viewed from the reference direction, and the second main body 90. Are stacked so as to be the lower layer. Specifically, the first fitting convex portion 83 and the second fitting convex portion 93 are fitted so that the first fitting convex portion 83 is positioned outside the second fitting convex portion 93, and the first fitting convex portion 93 is fitted. The first positioning convex portion 84 is overlapped with the second positioning convex portion 94 such that the positioning convex portion 84 is positioned outside the second positioning convex portion 94. When the first fitting convex portion 83 and the second fitting convex portion 93 are fitted, and the first positioning convex portion 84 is locked to the second positioning convex portion 94, the second of the first main body portion 80. The relative position with respect to the main body 90 is fixed.

  As shown in FIGS. 18 and 19, the annular plate portion 91 contacts the main plate portion 81 in a state where the first main body portion 80 and the second main body portion 90 are fitted. The transdermal administration device 20 is housed in a space surrounded by the housing recess 95, the main plate portion 81, and the housing projection 82. In the cross section along the reference direction, the positions of the respective parts in the reference direction are arranged in the order of the bottom of the housing recess 95, the annular plate 91, the main plate 81, and the top of the housing protrusion 82. The depth of the housing recess 95 and the height of the housing projection 82 in the reference direction may be the same or different.

  Here, the fitting structure between the first fitting convex portion 83 and the second fitting convex portion 93 will be described in detail. The first fitting convex portion 83 and the second fitting convex portion 93 are in a state where the first fitting convex portion 83 and the second fitting convex portion 93 are fitted, and the first fitting convex portion 83 is the first fitting convex portion 83. It is comprised so that it can rotate by making a reference direction into an axial direction around the 2 fitting convex part 93. As shown in FIG.

  For example, as shown in FIG. 20, the first fitting convex portion 83 includes a cylindrical portion 83a that extends vertically from the main plate portion 81, a diameter-expanded portion 83b that extends from the cylindrical portion 83a so as to expand in the radial direction thereof, The end plate portion 83 c is connected to the enlarged diameter portion 83 b and constitutes the top portion of the first fitting convex portion 83. The enlarged diameter portion 83b has a shape that curves outward in the radial direction in the cross section along the reference direction, and swells most radially in the center of the enlarged diameter portion 83b in the reference direction.

  The 2nd fitting convex part 93 is comprised from the cylindrical part 93a, the enlarged diameter part 93b, and the end plate part 93c. The tubular portion 93a extends vertically from the annular plate portion 91 and has a shape that can be fitted inside the tubular portion 83a of the first fitting convex portion 83, and the enlarged diameter portion 93b is formed by the tubular portion 93a. The end plate portion 93c is connected to the enlarged diameter portion 93b and has a second fit. The end fitting portion 83c has a shape that can be fitted to the inside of the enlarged diameter portion 83b of the first fitting convex portion 83. The top part of the joint convex part 93 is comprised.

  In a state where the first fitting convex portion 83 and the second fitting convex portion 93 are fitted, the cylindrical portion 83a slides along the outer peripheral surface of the cylindrical portion 93a, and on the outer peripheral surface of the enlarged diameter portion 93b. The diameter-expanded portion 83b slides along the center, with the center portion of the first fitting convex portion 83 and the second fitting convex portion 93 viewed from the reference direction outside the second fitting convex portion 93. The first fitting projection 83 rotates.

  Further, for example, as shown in FIG. 21, the first fitting convex portion 83 includes a cylindrical portion 83 d extending from the main plate portion 81, and an end plate connected to the cylindrical portion 83 d and constituting the top portion of the first fitting convex portion 83. A portion 83e may be included. The cylindrical portion 83d has a reduced diameter portion 83f that is recessed in the radial direction at the center portion in the reference direction.

  The second fitting convex portion 93 includes a tubular portion 93d and an end plate portion 93e, and the tubular portion 93d can be fitted inside the tubular portion 83d of the first fitting convex portion 83. Has a shape. That is, the cylindrical portion 93 d has a reduced diameter portion 93 f that can be fitted inside the reduced diameter portion 83 f of the first fitting convex portion 83.

  In a state where the first fitting convex portion 83 and the second fitting convex portion 93 are fitted, the cylindrical fitting portion 83d slides along the outer peripheral surface of the cylindrical portion 93d, whereby the second fitting convex portion. The first fitting convex portion 83 rotates around the center portion of the first fitting convex portion 83 and the second fitting convex portion 93 viewed from the reference direction on the outer side of 93.

  20 and 21, the first fitting convex portion 83 and the second fitting convex portion 93 include the first fitting convex portion 83 and the second fitting convex portion 93. What is necessary is just to be comprised so that the 1st fitting convex part 83 can rotate relatively with respect to the 2nd fitting convex part 93 by making the reference | standard direction into the axial direction of rotation in the state fitted.

[Detailed structure of transdermal administration device container]
A detailed configuration of the transdermal administration device housing 16 will be described with reference to FIG. FIG. 22 is an end view schematically showing an enlarged part of the transdermal administration device housing 16 in a state where the transdermal administration device 20 is accommodated in the accommodation unit 30.

  As shown in FIG. 22, in the transdermal administration device 20, the non-adhesive surface 24 </ b> T of the adhesive sheet 24 is supported on the bottom of the housing recess 95 of the second main body 90, and the tip of the protrusion 23 of the microneedle 21 is the first. It arrange | positions so that the ceiling surface inside the accommodating convex part 82 of the main-body part 80 may be opposed.

  The depth of the accommodation recess 95 along the thickness direction of the base body 22, that is, the reference direction is the accommodation length L3. In other words, the accommodation length L <b> 3 is a length along the reference direction in the space in the accommodation recess 95. The total length L4 of the transdermal administration device 20 is the length of the transdermal administration device 20 along the thickness direction of the substrate 22, and is in the reference direction from the non-adhesive surface 24T of the adhesive sheet 24 to the tip of the protrusion 23. Along the length.

  The accommodation length L3 is preferably larger than the sheet thickness L2. Further, the accommodation length L3 may be larger or smaller than the full length L4 of the transdermal administration device 20, or may be approximately the same as the full length L4. However, the accommodation length L3 is preferably not excessively smaller than the total length L4 in order to suppress the deformation of the projection portion 23 due to the contact between the accommodation portion 30 and the projection portion 23 when the accommodation portion 30 is opened. More preferably, it is larger than the total length L4.

  In addition, the length along the reference direction in the space in the accommodating convex portion 82 is such that the transdermal administration device 20 moves in the reference direction in the accommodating portion 30 until the non-facing surface 28S of the protective sheet 28 contacts the main plate portion 81. In this case, it is preferable that the tip of the protrusion 23 has a length that does not contact the inner ceiling surface of the housing projection 82.

[Action of transdermal device container]
Together with the operation of the transdermal administration device container 16 of the third embodiment, a procedure for taking out the transdermal administration device 20 from the accommodation unit 30 and administering the drug using the microneedle 21 will be described.

  As described above, the first fitting convex portion 83 and the second fitting convex portion 93 are fitted, and the first positioning convex portion 84 is locked to the second positioning convex portion 94, whereby transdermal administration. In a state where the device 20 is accommodated in the accommodating portion 30, the relative position of the first main body portion 80 with respect to the second main body portion 90 is fixed. Specifically, the first fitting protrusion 83 and the second fitting protrusion 93 are prevented from being separated from the first body portion 80 and the second body portion 90 in the reference direction. Due to the fitting and the first positioning convex portion 84 being hooked on the second positioning convex portion 94, in the direction orthogonal to the reference direction, that is, the direction along the first surface 22S of the base 22 of the microneedle 21. The first main body 80 is restrained from moving with respect to the second main body 90.

  As described above, also in the third embodiment, the pair of main bodies constituted by the first main body portion 80 and the second main body portion 90 is viewed from the reference direction, that is, the direction facing the first surface 22S of the base body 22. A fixing structure for fixing the relative position of the first main body 80 to the second main body 90 is provided outside the transdermal administration device 20. Accordingly, since the positions of the first main body 80 and the second main body 90 relative to each other are accurately fixed, the protection function of the transdermal administration device 20 by the housing 30 is enhanced.

  When the transdermal administration device 20 is taken out from the container 30, the user of the transdermal administration device 20 percutaneously places the second main body 90 under the transdermal administration device 20 as viewed from the user. An administration device housing 16 is arranged. And a user lifts the vicinity of the 1st positioning convex part 84 in the 1st main-body part 80 to such an extent that the 1st positioning convex part 84 does not catch on the 2nd positioning convex part 94, and a 1st fitting convex part. The first main body portion 80 is rotated using the fitting portion between the second fitting convex portion 93 and the fitting portion 83 as a fulcrum.

  That is, by rotating the first fitting convex portion 83 around the second fitting convex portion 93, the first main body portion 80 is moved in the direction along the first surface 22S as shown in FIG. It rotates relative to the part 90. As a result, the position of the first main body portion 80 with respect to the second main body portion 90 is shifted, the space between the first main body portion 80 and the second main body portion 90 is opened to the outside, and the accommodating portion 30 is opened. Thereby, the user can see the first surface 22S of the base 22 of the microneedle 21 and the non-facing surface 28S of the protective sheet 28 in the transdermal administration device 20. The user picks up the end portion of the protective sheet 28 and picks up the transdermal administration device 20 from the accommodation recess 95 of the second main body 90, thereby taking out the transdermal administration device 20 from the accommodation unit 30.

  At this time, in the second main body 90, the bottom of the connection recess 96 extends obliquely with respect to the annular plate 91 and the bottom of the receiving recess 95, and connects the annular plate 91 and the bottom of the receiving recess 95. It is out. Therefore, since the user can grip the transdermal administration device 20 by sliding his / her finger under the transdermal administration device 20 along the bottom of the connection recess 96, the transdermal administration device 20 can be easily removed from the accommodating portion 30. Can be taken out.

  As described above, when opening the housing part 30, the user rotates the first main body 80 while floating the first main body 80 with respect to the second main body 90. Therefore, even if the accommodation length L3 of the accommodation recess 95 is smaller than the total length L4 of the transdermal administration device 20, it is possible to suppress the contact between the accommodation portion 30 and the projection 23 when the accommodation portion 30 is opened. In order to suppress it, it is preferable that the accommodation length L3 is not excessively smaller than the full length L4, and more preferably larger than the full length L4 as described above.

  After removing the transdermal administration device 20, the user peels the protective sheet 28 from the adhesive sheet 24, presses the first surface 22 </ b> S of the base 22 of the microneedle 21 against the skin at the site where the drug is administered, and the base 22 The adhesive surface 24S of the adhesive sheet 24 that protrudes outside is attached to the skin. Thereby, the protrusion 23 perforates the skin and the drug is administered.

In the third embodiment, the annular plate portion 91 is an example of an outer peripheral portion, the bottom portion of the housing recess portion 95 is an example of a support plate portion, and the bottom portion of the connection recess portion 96 is an example of an inclined portion. The two main body portions 90 are target main body portions. Moreover, the 1st fitting convex part 83 and the 2nd fitting convex part 93 are examples of a fulcrum part, and the 1st positioning convex part 84 and the 2nd positioning convex part 94 are examples of a positioning structure, These fulcrum parts And the positioning structure constitute a fixed structure.
As described above, according to the transdermal administration device housing 16 of the third embodiment, the following effects can be obtained in addition to (1) and (5) of the first embodiment.

  (9) The first main body portion 80 and the second main body portion 90 are first in the direction along the first surface 22S with the first fitting convex portion 83 and the second fitting convex portion 93 as the center of rotation. The main body 80 is configured to be rotatable relative to the second main body 90. And the 1st main-body part 80 and the 2nd main-body part 90 are comprised by this rotation so that the space between the 1st main-body part 80 and the 2nd main-body part 90 can be open | released outside. According to such a configuration, it is easy to open the housing portion 30 as compared with a structure in which the first main body portion 80 and the second main body portion 90 are fixed to each other by adhesion or the like.

  (10) When the first positioning convex portion 84 is caught by the second positioning convex portion 94, the first main body portion 80 can be prevented from rotating in the direction along the first surface 22S with respect to the second main body portion 90. . Therefore, in the configuration in which the housing part 30 is opened by the rotation of the main body part, the relative position of the first main body part 80 with respect to the second main body part 90 is accurately fixed before the housing part 30 is opened.

[Modification of Third Embodiment]
The third embodiment may be implemented with the following modifications.
As in the first embodiment, the outer shapes of the first main body 80 and the second main body 90 as viewed from the reference direction may be different from those in the above embodiment. For example, the outer shape of the main plate portion 81 may be a rectangular shape with corners formed at right angles, a circular shape or an oval shape, and the outer shape of the annular plate portion 91 may be a corner portion. May be a rectangular ring formed at right angles, or an annular or elliptical ring. Further, the outer shape of the accommodating convex portion 82 is not limited to an elliptical shape.

  The shape of the connection recess 96 viewed from the reference direction is not limited to a semicircular shape. Further, the connection recess 96 may not be provided, and the upper end of the accommodation recess 95 may be connected to the inner peripheral edge of the annular plate portion 91 on the entire circumference of the accommodation recess 95.

  -The shape of the 1st positioning convex part 84 and the 2nd positioning convex part 94 is not restricted to the shape of the said embodiment, By the 1st positioning convex part 84 being hooked on the 2nd positioning convex part 94, the 1st main-body part 80 However, any shape that suppresses rotation in the direction along the first surface 22S relative to the second main body 90 may be used.

  In the above embodiment, the fitting structure of the first fitting convex portion 83 and the second fitting convex portion 93 constitutes a fulcrum portion that is the center of rotation of the first main body portion 80 relative to the second main body portion 90. However, for example, in the accommodating portion 30, the first main body portion 80 rotates with respect to the second main body portion 90 around the shaft-like member that penetrates the first main body portion 80 and the second main body portion 90 at the fulcrum portion. You may have the structure fixed as possible. In short, the fulcrum portion constitutes a part of the fixing structure of the first main body portion 80 and the second main body portion 90, and the first main body portion 80 extends in the direction along the first surface 22S around the fulcrum portion. It is only necessary that the relative rotation with respect to the second main body 90 is possible.

  -The accommodating part 30 rotates the 1st main-body part 80 relatively with respect to the 2nd main-body part 90 in the direction along the 1st surface 22S, and the 1st main-body part 80, the 2nd main-body part 90, It is sufficient that the space between the first body portion 80 and the second body portion 90 may be rotated when the container 30 is opened. Both the first main body 80 and the second main body 90 may rotate.

(Fourth embodiment)
A fourth embodiment of the transdermal administration device housing will be described with reference to FIGS. The transdermal administration device housing of the fourth embodiment is mainly different from the first embodiment in the structure for fitting the first body portion and the second body portion and the structure for opening the housing portion. Below, it demonstrates centering on difference with 1st Embodiment, about the structure similar to 1st Embodiment, the same code | symbol is attached | subjected and the description is abbreviate | omitted.

[Composition of housing part]
With reference to FIG. 24, the detailed structure of the accommodating part 30 with which the transdermal administration device accommodating body 17 of 4th Embodiment is provided is demonstrated.
As shown in FIG. 24, the accommodating portion 30 is composed of a first main body portion 100 and a second main body portion 110. The first main body portion 100 faces the first surface 22S of the base 22 and the non-facing surface 28S of the protective sheet 28 in the microneedle 21, and the second main body portion 110 is the non-adhesive surface 24T of the adhesive sheet 24 and the protective sheet 28. Opposite to the opposing surface 28T.

  In the description of the fourth embodiment, the reference direction is a direction along the direction in which the first main body portion 100 and the second main body portion 110 are overlapped, as in the third embodiment. Among them, it is a direction facing a portion directed to the outside of the housing portion 30 and a direction facing a portion facing the inside of the housing portion 30 in the second main body portion 110.

  The first main body 100 is composed of a plate-like main plate 101 that extends in a direction along the first surface 22S of the base 22 of the microneedle 21 as viewed from the reference direction, an accommodating convex 102 that protrudes from the main plate 101, Two first fitting convex portions 103 protruding from the main plate portion 101 are provided. Each of these parts is composed of a plate-like member having a substantially uniform thickness. When the first main body part 100 is viewed from the direction opposite to the reference direction, the convex part becomes a concave part, and the concave part has a convex part. It has become.

  The main plate 101 is surrounded by two sides that extend in a straight line and face each other as viewed from the reference direction, and two sides that extend in a bent line shape and connect the ends of the two straight sides. It has a shape. Specifically, in the direction orthogonal to the reference direction, that is, the direction along the main plate portion 101, the direction in which the linear side extends is the first direction, and the direction orthogonal to the first direction is the second direction. The outer edge of the main plate 101 extends linearly along the first direction at each of both ends of the main plate 101 in the second direction. On the other hand, the main plate portion 101 includes a plurality of first protruding portions 104 protruding toward the outside of the main plate portion 101 along the first direction at each of both end portions in the first direction. The plurality of first projecting portions 104 are arranged along the second direction at each of both end portions in the first direction of the main plate portion 101. As a result, the first projecting portions 104 adjacent to each other are arranged between the first projecting portions 104. A first recess 105 that is recessed along the direction is formed. In other words, the outer edge of the main plate portion 101 has a shape that undulates in a bent line shape at each of both end portions in the first direction of the main plate portion 101.

  In other words, when viewed from the reference direction, the first overhanging portion 104 has a shape protruding in the main plate portion 101 toward the outer side with respect to the transdermal administration device 20, and the plurality of first overhanging portions 104 are They are arranged outside the transdermal administration device 20.

  When viewed from the reference direction, the housing convex portion 102 is located at the center of the main plate portion 101 and has an elliptical shape. The outer shape of the housing convex portion 102 is larger than the outer shape of the region where the protruding portion 23 is arranged in the first surface 22S of the base 22 of the microneedle 21, and substantially matches the outer shape of the adhesive sheet 24, for example.

  When viewed from the reference direction, the first fitting convex portion 103 has an oval shape extending along the first direction, and each of the first fitting fittings is provided near each of both end portions of the main plate portion 101 in the second direction. The joint convex part 103 is arrange | positioned. The accommodation convex part 102 is arrange | positioned between the two 1st fitting convex parts 103 seeing from the reference direction.

  The second main body 110 includes a plate-shaped annular plate 111 that spreads in the direction along the first surface 22S of the base body 22 as viewed from the reference direction, an accommodation recess 112 that is recessed from the annular plate 111, and an annular plate. Two second fitting convex portions 113 projecting from 111 are provided. Each of these parts is composed of a plate-like member having a substantially uniform thickness. When the second main body part 110 is viewed from a direction opposite to the reference direction, the convex part becomes a concave part, and the concave part has a convex part. It has become.

  When viewed from the reference direction, the outer peripheral edge of the annular plate portion 111 having a ring shape is formed by connecting two edges that extend in a straight line and face each other, and end portions of the two straight lines that extend in a bent line shape. It has a shape composed of two sides. Specifically, the outer peripheral edge of the annular plate portion 111 extends linearly along the first direction at each of both end portions of the annular plate portion 111 in the second direction. On the other hand, the annular plate portion 111 includes a plurality of second projecting portions 114 that protrude toward the outside of the annular plate portion 111 along the first direction at each of both end portions in the first direction. The plurality of second projecting portions 114 are arranged along the second direction at each of both ends in the first direction of the annular plate portion 111. As a result, the second projecting portions 114 adjacent to each other are arranged between the second projecting portions 114 adjacent to each other. A second recess 115 that is recessed in one direction is formed. In other words, at each of both ends in the first direction of the annular plate portion 111, the outer peripheral edge of the annular plate portion 111 has a shape that undulates in a bent line shape.

  In other words, when viewed from the reference direction, the second projecting portion 114 has a shape projecting in the direction toward the outer side with respect to the transdermal administration device 20 in the annular plate portion 111, and the plurality of second projecting portions 114. Are arranged outside the transdermal administration device 20.

  When viewed from the reference direction, the housing recess 112 is positioned inside the annular plate portion 111 and has a substantially rectangular shape. When viewed from the reference direction, the four corners of the receiving recess 112 have a curved shape, and the outer shape of the receiving recess 112 matches the outer shape of the protective sheet 28 in the transdermal administration device 20 or the protective sheet 28. Slightly larger than the outer shape. The bottom of the housing recess 112 is parallel to the annular plate portion 111 and extends in a direction perpendicular to the reference direction.

  When viewed from the reference direction, the second fitting convex portion 113 has an oval shape extending along the first direction, and has a shape that can be fitted to the first fitting convex portion 103. Different second fitting convex portions 113 are arranged in the vicinity of both end portions in the second direction of the annular plate portion 111, and between the two second fitting convex portions 113 when viewed from the reference direction. A housing recess 112 is disposed.

  As shown in FIGS. 25 to 27, when the transdermal administration device 20 is accommodated, the first main body 100 is the second main body 110, the first main body 100 is the upper layer when viewed from the reference direction, and the second main body 110. Are stacked so as to be the lower layer. Specifically, the second fitting convex portion 113 is fitted to the first fitting convex portion 103 so that the first fitting convex portion 103 is positioned outside the second fitting convex portion 113. Thereby, the 1st main-body part 100 and the 2nd main-body part 110 fit so that release | release is possible, and the relative position with respect to the 2nd main-body part 110 of the 1st main-body part 100 is fixed.

  As shown in FIG. 25, in a state where the first main body portion 100 and the second main body portion 110 are fitted, the second overhang is formed between each of the two first overhang portions 104 adjacent to each other when viewed from the reference direction. The portion 114 is located, and the first overhanging portion 104 is located between each of the two second overhanging portions 114 adjacent to each other. In other words, when viewed from the reference direction, the first overhanging portion 104 and the second overhanging portion 114 do not completely overlap, and the first overhanging portion 104 and the second overhanging portion 114 are alternately arranged along the second direction. Lined up.

  As shown in FIGS. 26 and 27, in a state where the first main body portion 100 and the second main body portion 110 are fitted, the annular plate portion 111 is in contact with the main plate portion 101, and the second fitting convex portion 113 is the first fitting portion 113. It contacts the fitting convex part 103. The transdermal administration device 20 is housed in a space surrounded by the housing recess 112, the main plate portion 101, and the housing projection 102. In the cross section along the reference direction, the positions of the respective parts in the reference direction are arranged in the order of the bottom of the housing recess 112, the annular plate portion 111, the main plate portion 101, and the top of the housing projection 102. The position of the top portion of the first fitting convex portion 103 may be the same as or different from the position of the top portion of the accommodating convex portion 102. The depth of the housing recess 112 and the height of the housing projection 102 in the reference direction may be the same or different.

[Detailed structure of transdermal administration device container]
With reference to FIG. 28, the detailed structure of the transdermal administration device housing 17 will be described. FIG. 28 is an enlarged end view schematically showing a part of the transdermal administration device housing 17 in a state where the transdermal administration device 20 is accommodated in the accommodation unit 30.

  As shown in FIG. 28, in the transdermal administration device 20, the non-adhesive surface 24 </ b> T of the adhesive sheet 24 is supported on the bottom of the housing recess 112 of the second main body 110, and the tip of the protrusion 23 of the microneedle 21 is the first. It arrange | positions so that the ceiling surface inside the accommodating convex part 102 of the main-body part 100 may be opposed. The accommodation length L5, which is the depth of the accommodation recess 112 along the thickness direction of the substrate 22, that is, the reference direction, is preferably equal to or less than the sheet thickness L2. In other words, the accommodation length L5 is the length along the reference direction of the gap between the bottom of the accommodation recess 112 and the main plate portion 101. With such a configuration, the adhesive sheet 24 and the protective sheet 28 are sandwiched between the bottom of the housing recess 112 and the main plate 101, and these sheets are pressed by the bottom of the housing recess 112 and the main plate 101. The position of the transdermal administration device 20 in the interior of the housing part 30 is stabilized.

[Action of transdermal device container]
Together with the operation of the transdermal administration device housing 17 of the fourth embodiment, a procedure for taking out the transdermal administration device 20 from the housing 30 and administering the drug using the microneedle 21 will be described.

  As described above, by fitting the second fitting convex portion 113 to the first fitting convex portion 103, the transdermal administration device 20 is accommodated in the accommodating portion 30, so that the first body portion 100 is The relative position with respect to the second main body 110 is fixed. That is, also in the fourth embodiment, the body pair composed of the first body portion 100 and the second body portion 110 is located outside the transdermal administration device 20 as viewed from the reference direction. A fixing structure for fixing the position with respect to the second main body 110 is provided. Therefore, the protection function of the transdermal administration device 20 by the accommodating part 30 is enhanced.

  When the transdermal administration device 20 is taken out from the storage unit 30, the user of the transdermal administration device 20 percutaneously places the second main body 110 under the transdermal administration device 20 as viewed from the user. An administration device housing 17 is arranged. Then, the user of the transdermal administration device 20 pulls up the first main body 100 and removes the first main body 100 from the second main body 110. That is, the 1st fitting convex part 103 is removed from the 2nd fitting convex part 113, and the fitting with the 1st main-body part 100 and the 2nd main-body part 110 is cancelled | released.

  At this time, when viewed from the reference direction, the first projecting portions 104 and the second projecting portions 114 are alternately arranged without overlapping. Therefore, the user picks one of the first overhanging portions 104 and one of the second overhanging portions 114 with separate hands, directing the first overhanging portion 104 upward and the second overhanging portion 114 downward. The first main body 100 and the second main body 110 can be easily separated by pulling toward each other.

  By removing the first main body portion 100 from the second main body portion 110, the space between the first main body portion 100 and the second main body portion 110 is opened to the outside, and the accommodating portion 30 is opened. Thereby, the user can see the first surface 22S of the base 22 of the microneedle 21 and the non-facing surface 28S of the protective sheet 28 in the transdermal administration device 20. The user picks up the end portion of the protective sheet 28 and picks up the transdermal administration device 20 from the second main body 110 to take out the transdermal administration device 20 from the storage unit 30. Thereafter, the user peels off the protective sheet 28 from the adhesive sheet 24, presses the first surface 22 </ b> S of the base 22 of the microneedle 21 against the skin of the site where the drug is administered, and the adhesive sheet 24 protrudes outside the base 22. The adhesive surface 24S is affixed to the skin. Thereby, the protrusion 23 perforates the skin and the drug is administered.

  When opening the storage unit 30, the first main body unit 100 is disposed so that the first main body unit 100 is positioned below the transdermal administration device 20 when viewed from the user, and the second main body unit 110 is pulled up, whereby the first main body unit The second main body 110 may be removed from the 100.

  In the fourth embodiment, the main plate portion 101 is an example of a first plate-like portion, the annular plate portion 111 is an example of a second plate-like portion, and the main plate portion 101 is an example of a first opposing portion. The bottom of the housing recess 112 is an example of a second facing portion.

  As described above, according to the transdermal administration device housing 17 of the fourth embodiment, in addition to (1), (2), (7) of the first embodiment and (8) of the second embodiment. The following effects can be obtained.

  (11) Since the second overhanging portion 114 is located between the two first overhanging portions 104 adjacent to each other when viewed from the reference direction, the user makes the first overhanging portion 104 and the second overhanging portion 114 conflict with each other. The first main body 100 and the second main body 110 can be easily separated by pulling in the direction in which the first main body 100 is pulled. Therefore, opening of the accommodating part 30 is easy.

[Modification of Fourth Embodiment]
The fourth embodiment may be implemented with the following modifications.
The end portion where the first overhanging portion 104 is located may be different from that in the above embodiment, and the first overhanging portion 104 may be located at one end portion of the first main body portion 100 in the first direction. The 1st overhang | projection part 104 may be located in the edge part of 2 directions. Similarly, the end portion where the second projecting portion 114 is positioned may be different from that of the above embodiment, and the second projecting portion 114 may be positioned at one end portion in the first direction of the second main body portion 110. The second projecting portion 114 may be located at the end in the second direction. In short, it is only necessary that the second overhanging portion 114 is located between the first overhanging portions 104 adjacent to each other when viewed from the reference direction.

  -Like the 1st connection board part 48 of 1st Embodiment, and the connection recessed part 96 of 3rd Embodiment, the 2nd main-body part 110 connects the bottom part of the accommodation recessed part 112, and the cyclic | annular board part 111 inclining to these. A portion may be provided.

(Modification)
The above embodiments and modifications may be modified as follows.
-In 1st main-body part or 2nd main-body part, the plate-shaped part which comprises the side surface of a recessed part or a convex part may be extended in the reference direction, and may be extended in the direction inclined with respect to the reference direction. . However, when the first main body portion or the second main body portion is formed by resin molding, the direction in which the plate-like portion constituting the side surface of the concave portion or the convex portion extends in the direction inclined with respect to the reference direction is the first. Manufacture of the main body and the second main body is easy.

In the first body part and the second body part, the corner part which is a connection part between the part extending in the direction orthogonal to the reference direction and the part extending along the reference direction or in the direction inclined to the reference direction, It may have a curvature, or may form a right angle, an obtuse angle, or an acute angle. However, when the first body part or the second body part is formed by resin molding, it is easier to manufacture the first body part or the second body part if the corner part has a curvature.
-The 1st main-body part and the 2nd main-body part may be connected in one edge part seen from the reference direction.

  The outer edge of the adhesive sheet 24 and the outer edge of the protective sheet 28 may coincide with each other when viewed from the direction facing the first surface 22S of the base 22 of the microneedle 21. That is, the protective sheet may not include a portion that does not overlap with the adhesive sheet 24.

  -The shape of the projection part which an administration part has is not restricted to needle shape, ie, the shape extended along the direction which intersects perpendicularly with the 1st surface 22S of base 22. The shape of the protruding portion is a blade shape, that is, the protruding portion extends along one extending direction that is the direction along the first surface 22S of the base body 22, and the tip of the protruding portion is the first surface 22S of the base body 22. The shape may be a linear shape extending in a direction different from the direction orthogonal to the direction, for example, the extending direction. For example, the protruding portion has a triangular prism shape extending along the extending direction, and one of three rectangular side surfaces of the triangular column is in contact with the base 22, and the side that divides the other two side surfaces protrudes. You may have the shape which functions as a front-end | tip of a part.

  DESCRIPTION OF SYMBOLS 10, 15, 16, 17 ... Transdermal administration device container, 20 ... Transdermal administration device, 21 ... Microneedle, 22 ... Base | substrate, 22S ... 1st surface, 22T ... 2nd surface, 23 ... Projection part, 24 ... Adhesive sheet, 24S ... Adhesive surface, 24T ... Non-adhesive surface, 28 ... Protective sheet, 28S ... Non-opposing surface, 28T ... Opposing surface, 30 ... Housing part, 40, 60, 80, 100 ... First main body part, 50, 70, 90, 110 ... second body portion, 41 ... first annular plate portion, 42 ... first annular convex portion, 43 ... first support plate portion, 44 ... receiving recess, 45 ... starting point portion, 46 ... first side plate 47, first upper plate portion, 48, first connection plate portion, 49, first raised portion, 51, second annular plate portion, 52, second annular convex portion, 53, second support plate portion, 56. ... 2nd side board part, 57 ... 2nd upper board part, 58 ... 2nd connection board part, 59 ... 2nd protruding part, 61 ... 1st annular board part 62 ... 1st belt-shaped recessed part, 71 ... 2nd annular plate part, 72 ... 2nd belt-shaped recessed part, 81 ... main plate part, 82 ... accommodation convex part, 83 ... 1st fitting convex part, 84 ... 1st positioning convex part, 91 ... annular plate part, 93 ... second fitting convex part, 94 ... second positioning convex part, 95 ... accommodating concave part, 96 ... connection concave part, 101 ... main plate part, 102 ... accommodating convex part, 103 ... first fitting Convex part 104 ... first overhang part 105 ... first indent part 111 ... annular plate part 112 ... accommodating concave part 113 ... second fitting convex part 114 ... second overhang part 115 ... second indent part .

Claims (11)

A transdermal administration device housing comprising a transdermal administration device and a housing for housing the transdermal administration device,
The transdermal administration device comprises:
A dosing unit comprising a base having a first surface and a second surface opposite to the first surface; and a protrusion protruding from the first surface;
An adhesive sheet having an adhesive surface to which the second surface is attached and a non-adhesive surface opposite to the adhesive surface, wherein the adhesive surface is viewed from a direction facing the first surface. A part of the pressure-sensitive adhesive sheet protruding outside the substrate;
A protective sheet attached to a region protruding from the base body in the adhesive surface,
The accommodating portion is
A first main body portion facing the first surface of the base; and a second main body portion facing the non-adhesive surface of the adhesive sheet; and the first main body portion and the second main body portion. Having a space in which the transdermal administration device is located,
The main body pair composed of the first main body portion and the second main body portion is located on the outer side of the transdermal administration device when viewed from the direction facing the first surface. (2) A transdermal administration device container comprising a fixing structure for releasably fixing a relative position to a main body part. The fixing structure is a fitting structure in which the first body portion and the second body portion are fitted,
The percutaneous structure according to claim 1, wherein the housing part is configured to be able to open a space between the first main body part and the second main body part to the outside by releasing the fitting in the fitting structure. Dosing device container. The transdermal administration device housing according to claim 2, wherein the fitting structure is positioned in an annular shape surrounding the transdermal administration device when viewed from a direction facing the first surface. The transdermal administration device housing according to claim 2, wherein the main body pair includes a plurality of the fitting structures outside the transdermal administration device when viewed from a direction facing the first surface. When viewed from the direction facing the first surface, the main body pair includes a portion in which an end portion of the first main body portion does not overlap the second main body portion, and an end portion of the second main body portion. The transdermal administration device container according to any one of claims 2 to 4, satisfying at least one of: a portion that does not overlap with the first main body portion. The first body portion includes a first plate-like portion having a plate shape extending in a direction along the first surface,
The second body portion includes a second plate-like portion having a plate shape extending in a direction along the first surface,
The first plate-like portion has a shape protruding in a direction outward from the transdermal administration device in the first plate-like portion when viewed from the direction facing the first surface, and A plurality of first overhang portions arranged outside the transdermal administration device,
The second plate-like portion has a shape protruding in a direction outward from the transdermal administration device in the second plate-like portion when viewed from the direction facing the first surface, and A plurality of second overhangs arranged outside the transdermal administration device,
The transdermal administration device according to any one of claims 2 to 4, wherein the second overhanging portion is located between the two first overhanging portions adjacent to each other when viewed from the direction facing the first surface. Container. The fixing structure includes a fulcrum portion,
The main body pair is configured to rotate in a direction along the first surface with the fulcrum portion as a center of rotation, and capable of rotating the first main body portion relative to the second main body portion. The transdermal administration device housing according to claim 1, wherein a space between the first main body portion and the second main body portion can be opened to the outside by the rotation. The fixing structure includes a positioning structure;
The positioning structure is a structure in which one of the first main body portion and the second main body portion is hooked on the other, and the structure prevents the relative rotation of the first main body portion with respect to the second main body portion by the hook. A transdermal device housing according to claim 7. Either one of the first body part and the second body part is a target body part,
The target body portion is
A support plate for supporting the transdermal administration device;
As seen from the direction facing the support plate portion, an outer peripheral portion surrounding the support plate portion and disposed at a position elevated from the support plate portion,
An inclined part that is inclined with respect to the support plate part and connects at least a part of the outer edge of the support plate part and at least a part of the inner peripheral edge of the outer peripheral part. The transdermal administration device container described in 1. The target body portion includes a plurality of raised portions raised from the inclined portion,
10. The transdermal administration device housing according to claim 9, wherein two ridges included in the plurality of bulges are arranged at positions sandwiching the transdermal administration device as viewed from a direction facing the support plate. body. The protective sheet has a facing surface directed to the adhesive surface and a non-facing surface that is a surface opposite to the facing surface;
The first body portion includes a first facing portion that faces the non-facing surface of the protective sheet,
The second body portion includes a second facing portion that faces the non-adhesive surface of the pressure-sensitive adhesive sheet,
The first facing portion and the second facing portion face each other across the space where the transdermal administration device is located, and the first facing portion and the second facing portion along a direction facing the first surface. The transdermal administration device container according to claim 1, wherein a length between the parts is equal to or less than a total length of the thickness of the protective sheet and the thickness of the adhesive sheet.