JP2017184787A5 - - Google Patents

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JP2017184787A5
JP2017184787A5 JP2016073730A JP2016073730A JP2017184787A5 JP 2017184787 A5 JP2017184787 A5 JP 2017184787A5 JP 2016073730 A JP2016073730 A JP 2016073730A JP 2016073730 A JP2016073730 A JP 2016073730A JP 2017184787 A5 JP2017184787 A5 JP 2017184787A5
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photographing
illumination light
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少なくとも1つのレンズを含む対物レンズ系と、光源から発せられた照明光を前記対物レンズ系を介して被検眼に照射する照射光学系と、前記被検眼による前記照明光の反射光を前記対物レンズ系を介して受光する受光素子を備える受光光学系と、を含む撮影光学系と、を備え、前記受光素子からの信号に基づいて撮影画像を生成する眼科撮影装置であって、
被検眼の正面画像を前記撮影画像として得る正面画像撮影手段と、
前記正面画像撮影手段で取得される前記被検眼の正面画像に対する背景画像であって,少なくとも前記対物レンズ系による反射像を含む背景画像を取得する背景画像取得手段と、
前記被検眼の正面画像と前記背景画像とに基づく背景差分を行い、差分画像として、前記被検眼の正面画像において前記反射像の影響が抑制された画像を生成する画像処理手段と、を備える眼科撮影装置。
An objective lens system including at least one lens, an irradiation optical system for irradiating illumination light emitted from a light source to an eye to be examined through the objective lens system, reflection light of the illumination light by the eye to be examined An ophthalmologic imaging apparatus comprising: an imaging optical system including a light receiving element including a light receiving element that receives light via a system; and generating a photographed image based on a signal from the light receiving element,
Front image photographing means for obtaining a front image of an eye to be examined as the photographed image;
Background image acquiring means for acquiring a background image with respect to the front image of the eye to be examined acquired by the front image photographing means, the background image including a reflection image by at least the objective lens system;
An ophthalmologist comprising: image processing means for performing background subtraction based on the front image of the eye and the background image, and generating an image in which the influence of the reflection image is suppressed in the front image of the eye as a difference image; Shooting device.
前記背景画像取得手段は、前記対物レンズ系において前記反射像を生じさせるレンズ,の被検眼側を遮光した遮光状態での撮影による前記撮影画像を、前記背景画像として取得する請求項1記載の眼科撮影装置。   The ophthalmology according to claim 1, wherein the background image acquisition means acquires the photographed image obtained by photographing in a light shielding state in which the subject eye side of the lens for producing the reflected image in the objective lens system is shielded from light as the background image. Shooting device. 前記背景画像取得手段は、前記照明光の出力,受光信号のゲイン,および,前記撮影光学系の視度,の少なくともいずれかに関する撮影条件を切換えながら前記撮影条件が互いに異なる複数の前記背景画像を、前記遮光状態での撮影を繰り返すことで予め取得し、
前記画像処理手段は、予め取得された複数の背景画像の中から前記撮影条件が前記被検眼の正面画像と対応するものを選択して,前記背景差分を行う請求項記載の眼科撮影装置。
The background image acquiring unit changes a plurality of background images having different imaging conditions while switching an imaging condition related to at least one of the output of the illumination light, the gain of the light reception signal, and the diopter of the imaging optical system. Acquired in advance by repeating the photographing in the light shielding state,
The ophthalmologic photographing apparatus according to claim 2 , wherein the image processing means selects one of the plurality of background images acquired in advance, in which the photographing condition corresponds to the front image of the eye to be examined, and performs the background subtraction.
前記背景画像取得手段は、前記照明光の出力,および,受光信号のゲイン,の少なくともいずれかに関する撮影条件が,第1の撮影条件であるときの前記背景画像を、少なくとも1つ予め取得し、
前記画像処理手段は、前記正面画像撮影手段によって前記被検眼の正面画像が撮影されたときの撮影条件である第2の撮影条件が、前記背景画像における前記第1の撮影条件と異なる場合、前記被検眼の正面画像および前記背景画像の少なくとも一方におけるコントラストまたは明るさを整合させ、整合後の画像に基づいて前記背景差分を行う請求項記載の眼科撮影装置。
The background image acquisition means acquires in advance at least one background image when a photographing condition regarding at least one of the output of the illumination light and the gain of the light reception signal is a first photographing condition,
When the second imaging condition which is the imaging condition when the front image of the eye to be examined is imaged by the front image imaging means, the image processing means is different from the first imaging condition in the background image The ophthalmologic photographing apparatus according to claim 2, wherein the contrast or the brightness in at least one of the front image and the background image of the eye to be examined is matched, and the background difference is performed based on the matched image.
前記正面画像撮影手段は、第1波長の照明光である第1照明光,および,前記第1波長とは異なる第2波長を持つ第2照明光,のそれぞれを前記照射光学系から前記被検眼に照射させて、前記第1照明光の反射光に基づく被検眼の第1正面画像と、前記第2照明光の反射光に基づく被検眼の第2正面画像と、を撮影し、
前記背景画像取得手段は、前記第1照明光に基づく背景画像である第1背景画像と、前記第2照明光に基づく背景画像である第2背景画像と、を取得し、
前記画像処理手段は、前記第1正面画像と前記第1背景画像とに基づく第1差分画像,および,前記第2正面画像と前記第2背景画像とに基づく第2差分画像,とを合成して合成差分画像を得る請求項1からのいずれかに記載の眼科撮影装置。
The front image photographing means is configured to receive each of the first illumination light, which is illumination light of a first wavelength, and the second illumination light, which has a second wavelength different from the first wavelength, from the illumination optical system The first front image of the eye to be examined based on the reflected light of the first illumination light, and the second front image of the eye to be examined based on the reflected light of the second illumination light;
The background image acquisition means acquires a first background image which is a background image based on the first illumination light, and a second background image which is a background image based on the second illumination light,
The image processing means combines a first difference image based on the first front image and the first background image, and a second difference image based on the second front image and the second background image. The ophthalmologic photographing apparatus according to any one of claims 1 to 4 , wherein the synthetic differential image is obtained.
前記正面画像撮影手段は、第1波長の照明光である第1照明光,および,前記第1波長とは異なる第2波長を持つ第2照明光,のそれぞれを前記照射光学系から前記被検眼に照射させて、前記第1照明光の反射光に基づく第1正面画像と、前記第2照明光の反射光に基づく第2正面画像と、を撮影し、
前記背景画像取得手段は、前記第1照明光に基づく背景画像である第1背景画像と、前記第2照明光に基づく背景画像である第2背景画像と、を取得し、
前記画像処理手段は、前記第1正面画像と前記第2正面画像との第1合成画像と、前記第1背景画像と前記第2背景画像との合成画像と、に基づく背景差分によって合成差分画像を得る請求項1からのいずれかに記載の眼科撮影装置。
The front image photographing means is configured to receive each of the first illumination light, which is illumination light of a first wavelength, and the second illumination light, which has a second wavelength different from the first wavelength, from the illumination optical system The first front image based on the reflected light of the first illumination light and the second front image based on the reflected light of the second illumination light,
The background image acquisition means acquires a first background image which is a background image based on the first illumination light, and a second background image which is a background image based on the second illumination light,
The image processing means generates a composite difference image by a background difference based on a first composite image of the first front image and the second front image, and a composite image of the first background image and the second background image. The ophthalmologic imaging apparatus according to any one of claims 1 to 5 , wherein
前記撮影光学系は、眼底画像を撮影画像として得るための光学系であって、
眼底反射光による眼底画像を撮影するための第1撮影モードと、眼底から発せられた蛍光による眼底画像を撮影するための第2撮影モードと、に少なくとも前記光源を制御して切替える切換制御手段を有し、
前記画像処理手段は、前記第1撮影モードにおいて撮影された前記眼底画像に対しては前記背景差分を行い、前記第2撮影モードにおいて撮影された前記眼底画像に対しては前記背景差分を行わない請求項1からの何れかに記載の眼科撮影装置。
The photographing optical system is an optical system for obtaining a fundus oculi image as a photographed image, and
Switching control means for controlling and switching at least the light source between a first imaging mode for imaging a fundus image by fundus reflected light and a second imaging mode for capturing a fundus image by fluorescence emitted from the fundus Have
The image processing means performs the background subtraction on the fundus image captured in the first imaging mode and does not perform the background subtraction on the fundus image captured in the second imaging mode The ophthalmologic imaging device according to any one of claims 1 to 6 .
前記撮影光学系は、前記撮影画像を第1の画角で撮影するための第1撮影モードと、前記撮影画像を前記第1の画角よりも狭い画角で撮影するための第2撮影モードとに、切り替え可能であり、
前記画像処理手段は、前記第1撮影モードにおいて撮影された前記被検眼の正面画像に対しては前記背景差分を行い、前記第2撮影モードにおいて撮影された前記被検眼の正面画像に対しては前記背景差分を行わない請求項1からの何れかに記載の眼科撮影装置。
The photographing optical system includes a first photographing mode for photographing the photographed image at a first angle of view, and a second photographing mode for photographing the photographed image at an angle of view narrower than the first angle of view And can be switched,
The image processing means performs the background subtraction on the front image of the subject's eye taken in the first imaging mode, and the front image of the subject's eye taken in the second imaging mode. The ophthalmologic imaging apparatus according to any one of claims 1 to 7 , wherein the background subtraction is not performed.
前記正面画像撮影手段と前記背景画像取得手段とは、第1の階調数で表現される前記被検眼の正面画像と前記背景画像とをそれぞれ取得し、
前記画像処理手段は、前記第1の階調数で表現される前記被検眼の正面画像と前記背景画像との背景差分を行い、前記第1の階調数よりも少ない第2の階調数で表現される差分画像を生成する請求項1からのいずれかに記載の眼科撮影装置。
The front image photographing means and the background image acquisition means respectively acquire a front image of the eye to be examined and the background image represented by a first gradation number,
The image processing means performs a background difference between the front image of the eye to be examined and the background image represented by the first number of gradations, and a second number of gradations smaller than the first number of gradations The ophthalmologic imaging apparatus according to any one of claims 1 to 8 , which generates a differential image represented by
少なくとも1つのレンズを含む対物レンズ系を介して被検眼に照明光を投光し、前記被検眼からの反射光に基づいて被検眼の正面画像を得る眼科撮影装置による撮影画像を処理するための画像処理プログムであって、コンピュータのプロセッサで実行されることにより、
前記眼科撮影装置による前記被検眼の正面画像を取得する第1取得ステップと、
少なくとも前記対物レンズ系による照明光の反射像を含む前記被検眼の正面画像における背景画像を取得する第2取得ステップと、
前記被検眼の正面画像と前記背景画像とに基づく背景差分を行い、差分画像として、前記被検眼の正面画像における前記反射像の影響が抑制された画像を生成する画像処理ステップと、
を前記コンピュータに実行させることを特徴とする画像処理プログラム。
For processing an image taken by an ophthalmologic photographing apparatus which projects illumination light to an eye to be examined through an objective lens system including at least one lens and obtains a front image of the eye to be examined based on reflected light from the eye to be examined An image processing program, which is executed by a processor of a computer,
A first acquisition step of acquiring a front image of the eye to be examined by the ophthalmologic imaging apparatus;
A second acquisition step of acquiring a background image in a front image of the subject's eye including at least a reflection image of illumination light by the objective lens system;
An image processing step of performing background subtraction based on the front image of the eye and the background image to generate an image in which the influence of the reflection image on the front image of the eye is suppressed as a difference image;
An image processing program causing the computer to execute the program.
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WO2019189222A1 (en) * 2018-03-30 2019-10-03 株式会社ニコン Ophthalmic optical system, object lens for ophthalmology, and ophthalmic device
JP7051041B2 (en) * 2018-05-08 2022-04-11 株式会社ニデック Wide-angle attachment and fundus photography device
US11219362B2 (en) 2018-07-02 2022-01-11 Nidek Co., Ltd. Fundus imaging apparatus
JP7200516B2 (en) * 2018-07-02 2023-01-10 株式会社ニデック Fundus camera
JP7376847B2 (en) * 2019-12-26 2023-11-09 株式会社ニデック Fundus image processing device and fundus image processing program

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US9456746B2 (en) * 2013-03-15 2016-10-04 Carl Zeiss Meditec, Inc. Systems and methods for broad line fundus imaging

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