JP2017132695A - Foamy aerosol - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a foamy aerosol capable of sufficiently supplying hydrogen to the skin and having compatible feeling and penetration feeling to the skin.SOLUTION: There is provided a foamy aerosol 1 obtained by filling a liquid composition 3, a liquefied gas 4 for ejecting the liquid composition and hydrogen 5 in a pressure-resistant container 2. The liquid composition 3 comprises at least a surfactant. The ejection pressure at 20°C of the foamy aerosol preferably is less than 1 MPa. The mass ratio of a mixture of the liquefied gas 4 and the hydrogen 5 to the composition 3 preferably is 40:60 to 90:10.SELECTED DRAWING: None

Description

  The present invention relates to a foamy aerosol containing hydrogen.

  Although active oxygen having strong oxidizing power generated in the body is essential for life support, it is known that excessive active oxygen promotes aging of skin cells. Specifically, it has been pointed out that active oxygen causes wrinkles and blemishes and causes skin loss. On the other hand, hydrogen is considered to be effective in removing surplus active oxygen in cells because active oxygen is reduced to produce water. However, since hydrogen is an extremely small molecule and is easily taken into the body, it is difficult to maintain a hydrogen-containing state because it is easily diffused into the atmosphere.

  In recent years, hydrogen water in which drinking water or the like is filled with hydrogen gas has been commercially available for the purpose of reducing active oxygen. However, hydrogen has a very low solubility in water. Furthermore, since hydrogen molecules are very small, even if hydrogen water is sealed in a plastic container such as a plastic bottle, hydrogen passes through the container. Therefore, there is a problem that it is difficult to supply hydrogen water sufficiently containing hydrogen.

  Therefore, a method of maintaining the dissolved hydrogen amount of hydrogen water by attaching a pressure member to the container has been developed (see Patent Document 1). Moreover, the manufacturing method of the functional gel which made the gel contain hydrogen etc. is developed (refer patent document 2). Further, aerosols have been developed that spray a liquid composition using hydrogen as a propellant in the form of a mist.

JP 2011-136727 A JP 2011-245471 A JP2015-86220A

  However, even if the amount of dissolved hydrogen in the hydrogen water is increased by pressurizing the container as described above, if the contents are taken out of the container or the part of the container is opened at the time of use, the hydrogen is immediately removed from the hydrogen water into the atmosphere. Will spread. Further, even in a functional gel in which hydrogen or the like is contained in the gel, when the gel is dissolved, the hydrogen concentration may be remarkably lowered, and management of storage conditions such as temperature is required. On the other hand, the above-mentioned hydrogen-containing aerosol is excellent in that the contents are held in a pressure resistant container and a necessary amount can be taken out during use. However, since the contents are injected in the form of a mist, hydrogen may be retained between the mist-like water molecules, but most of the hydrogen is diffused into the atmosphere during spraying and is then applied to the skin. It is considered difficult to supply a sufficient amount of hydrogen. In addition, a mist-like aerosol has a low feeling of familiarity with the skin, and a penetrating feeling is difficult to obtain. That is, there is room for improvement in the feeling of use.

  The present invention has been made in view of such problems, and is intended to provide a foamy aerosol that can sufficiently supply hydrogen to the skin and has excellent fit and penetration into the skin. is there.

  As a result of intensive studies to solve the above-mentioned problems, the present inventors have found that a foamy aerosol containing hydrogen can sufficiently supply hydrogen to the skin, and the familiarity and penetration into the skin. The present inventors have found that the feeling is excellent and have reached the present invention. That is, the gist of the present invention is the following [1] to [9].

[1] a liquid composition containing at least a surfactant;
A liquefied gas for injecting the composition;
A foamy aerosol filled with hydrogen and a pressure-resistant container.

[2] The foamy aerosol according to [1], wherein an injection pressure at a temperature of 20 ° C. is less than 1 MPa.

[3] The foam aerosol according to [1] or [2], wherein a mass ratio of the mixture of the liquefied gas and the hydrogen and the composition is 1:99 to 90:10.

[4] The foam aerosol according to any one of [1] to [3], wherein an internal pressure ratio of an injection pressure of the liquefied gas and the hydrogen is 1: 9 to 99.9: 0.1.

[5] The liquefied gas is at least one selected from the group consisting of liquefied petroleum gas, dimethyl ether, trans-1,3,3,3-tetrafluoropropane-1-ene, and carbon dioxide gas. [1] -Foam aerosol in any one of [4].

[6] The foam aerosol according to any one of [1] to [5], wherein the content of the surfactant in the composition is 0.01 to 50% by mass.

[7] The foam aerosol according to any one of [1] to [6], wherein the composition is a cosmetic.

[8] The foam aerosol according to any one of [1] to [7], wherein the viscosity of the composition is 1 to 100,000 Pa · s.

[9] The foamed aerosol according to any one of [1] to [8], wherein the foamed composition containing hydrogen formed by spraying from the pressure-resistant container is applied to the skin.

[10] The foam according to any one of [1] to [9], wherein the foam-like composition is used by jetting from the pressure-resistant container in a state where the injection port of the pressure-resistant container is disposed vertically downward. Aerosol.

  The foamy aerosol has a liquid composition, a liquefied gas for injecting the composition, hydrogen, and a pressure vessel filled with these. In the foamed aerosol having such a configuration, not only the liquefied gas but also hydrogen can serve as a so-called propellant for ejecting the composition. And a foam-like composition can be injected from the inside of a pressure-resistant container with liquefied gas and hydrogen, and hydrogen is hold | maintained in the bubble of a foam-like composition. Therefore, it becomes possible to supply hydrogen sufficiently to the skin by applying to the skin the foam composition ejected from the foam aerosol.

  Furthermore, since at least a surfactant is contained in the composition in the pressure vessel, the composition can be easily foamed when the composition is sprayed from the foam aerosol, and the foam The state is easy to be maintained. Therefore, since the foam-like composition containing hydrogen can be hold | maintained on skin, it becomes possible to supply hydrogen sufficiently to skin. Moreover, a foam-like composition is excellent in a usability | use_condition. That is, the user's feeling of familiarity with the skin is good, and a high penetration feeling is obtained by foam stimulation or the like.

1 is a cross-sectional view of a foam aerosol in Example 1. FIG. Sectional drawing of the foamy aerosol which arrange | positioned the injection nozzle in the perpendicular direction downward in Example 1. FIG. Sectional drawing of the foamy aerosol in Example 3. FIG.

<Surfactant>
The liquid composition contains at least a surfactant. The surfactant can suppress foam breakage in the foam-like composition and can stabilize the bubbles. In order to sufficiently obtain such an effect, the content of the surfactant in the composition is preferably 0.01 to 50% by mass, and more preferably 0.1 to 20% by mass. As the surfactant, for example, nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, petroleum derivative surfactants, and combinations thereof can be used.

  As the nonionic surfactant, for example, at least one selected from the group consisting of poly (oxyethylene) alkyl ether, polyoxyethylene fatty acid ester, poloxamer, meloxapol, sorbitan fatty acid ester, and polysiloxane derivative can be used.

  The number of ethylene oxides in the poly (oxyethylene) alkyl ether is preferably 4-8, and the number of alkyl groups is preferably 6-20. Specific examples of poly (oxyethylene) alkyl ethers include, for example, Laureth-4, Laureth-9, Undesses-9, Cetes-1, Ceteares-2, Steareth-1, Steareth-2, Steareth-21, PEG-2 stear Rate, PEG-6 stearate, PEG-8 dilaurate, their salts, and mixtures thereof. Among these, Laureth-4 is preferable. “PEG” means “polyethylene glycol”.

  Specific examples of polyoxyethylene fatty acid esters include, for example, PEG-2 dilaurate, PEG-150 laurate, PEG-150 distearate, PEG-78 glyceryl cocoate, PEG-30 glyceryl cocoate, PEG-2 stearate, PEG-4 stearate, PEG -6 stearate, PEG-10 stearate, PEG-12 stearate, PEG-20 glyceryl stearate, PEG-80 glyceryl tallowate, PPG-10 glyceryl stearate, PEG-80 glyceryl cocoate, PEG-200 glyceryl tallowate, PEG-8 dilaurate, PEG-10 distearate, PEG-60 hydrogenated castor oil, PEG-50 hydrogenated castor oil, PEG-40 hydrogenated castor oil, PEG-30 hydrogenated castor oil, PEG 20 hydrogenated castor oil, PEG-10 hydrogenated castor oil, salts thereof, and mixtures thereof. Among these, PEG-2 dilaurate is preferable. “PPG” means “polypropylene glycol”.

  Specific examples of poloxamers include, for example, poloxamer 188, poloxamer 124, poloxamer 237, poloxamer 338, poloxamer 407, pluronic, splenic, simperonic, monolan, lutrol, salts thereof, and mixtures thereof. Of these, poloxamer 188 is preferred.

  Specific examples of meloxapol include, for example, meloxapol 258, meloxapol 105, meloxapol 108, meloxapol 171, meloxapol 172, meloxapol 174, meloxapol 178, meloxapol 251, meloxapol 252, meloxapol 254, meloxapol 311 and meloxapol 311 , Their salts, and mixtures thereof. Among these, meloxapol 258 is preferable.

  Specific examples of sorbitan fatty acid esters include polysorbate 60, sorbitan monostearate, sorbitan laurate, sorbitan oleate, sorbitan palmitate, sorbitan stearate, sorbitan trioleate, sorbitan sesquioleate, sorbitan monoisostearate, sesquioxane Sorbitan isostearate, sorbitan trilaurate, sorbitan tristearate, sorbitan di-isostearate, sorbitan dioleate, sorbitan sesquistearate, sorbitan tri-isostearate, polysorbate 20, polysorbate 21, polysorbate 40, polysorbate 61, polysorbate 65, Polysorbate 80, polysorbate 81, polysorbate 85, polysorbate 120, it Salts, and mixtures thereof. Among these, polysorbate 60 and sorbitan monostearate are preferable.

  Specific examples of polysiloxane derivatives include, for example, dimethicone, poly (dimethylsiloxane) (ie, PDMS), cyclomethicone, hexomethylmethicone, polymethyl-hydrosiloxane (ie, PMHS), cyclotetra (methylhydrosiloxane) (ie, D4H), diethyl polysiloxane, high molecular weight dimethicone, mixed C1-C30 alkyl polysiloxane, phenyl dimethicone, dimethiconol, salts thereof, and mixtures thereof. Of these, dimethicone is preferred.

  As the anionic surfactant, for example, at least one selected from the group consisting of fatty acids, sulfated fatty acids, phosphorylated fatty acids, sulfosuccinates, and salts thereof can be used.

  Specific examples of fatty acids include, for example, lauric acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, linoleic acid, linolenic acid, eleostearic acid, arachidonic acid, isostearic acid, hydroxystearic acid, ricinolenic acid, Behenic acid, erucic acid, lanolinic acid, their salts, and mixtures thereof are included. The fatty acid preferably has 12 to 24 carbon atoms, and may be a saturated fatty acid or an unsaturated fatty acid. Of these, stearic acid is preferred.

  The sulfated fatty acid preferably has 12 to 24 carbon atoms and contains a salt. In the case of a salt, a lithium salt, a sodium salt, or a potassium salt is preferable. Specific examples of sulfated fatty acids include sodium lauryl sulfate, sodium laureth-3 sulfate, ammonium lauryl sulfate, ammonium laureth-3 sulfate, potassium lauryl sulfate, potassium laureth-3 sulfate, lauryl sulfate TEA, laureth-3 sulfate TEA, and the like. Salts, and mixtures thereof are included. Among these, sodium lauryl sulfate is preferable. “TEA” means “triethanolamine”.

  The phosphorylated fatty acid preferably has 12 to 24 carbon atoms and includes a salt. In the case of a salt, beryllium salt, magnesium salt, and calcium salt are preferable.

  The sulfosuccinate preferably has 4 to 20 carbon atoms and contains a salt. In the case of a salt, a lithium salt, a sodium salt, or a potassium salt is preferable. Specific examples of the sulfosuccinate include, for example, dioctyl sodium sulfosuccinate, diethylhexyl sodium sulfosuccinate, sodium bis (2-ethylhexyl) sulfosuccinate, disodium N-octadecyl sulfosuccinate, disodium Lauryl sulfosuccinate, diammonium lauryl sulfosuccinate, tetrasodium N- (1,2-dicarboxyethyl) -N-octadecyl sulfosuccinate, sodium dioctyl sulfosuccinate, disodium oleamide MEA sulfos Succinates, their salts, and mixtures thereof. Among these, dioctyl sodium sulfosuccinate, diethylhexyl sodium sulfosuccinate, and salts thereof are preferable. “MEA” means “monoethanolamine”.

  As the cationic surfactant, for example, a tertiary alkanolamine, that is, N, N, N-trihydroxyalkylamine, or a salt thereof can be used. Each of the three alkyl groups contained in the amine preferably has 1 to 9 carbon atoms. Specific examples of such cationic surfactants include, for example, triethanolamine, triilopropanolamine, diethanoltriisopropanolamine, trimethanolamine, tributanolamine, propanol-diethanolamine, salts thereof, and mixtures thereof. included. Among these, triethanolamine is preferable.

  As the amphoteric surfactant, for example, betaine type or sulfobetaine type can be used. The amphoteric surfactant may be an acid or a salt thereof. In the case of a salt, a lithium salt, a sodium salt, or a potassium salt is preferable. Specific examples of amphoteric surfactants include cocoamphopropionic acid, cocoamphocarboxypropionic acid, cocoamphocarboxypropionic acid, conamphoglycinate, cocoamphocarboxyglycinate, cocoamphoacetate, cocoamphodiacetate, cocoamphodipropionate , Alkyl glycinate, propionate, imidazoline, amphoalkyl sulfonate, N-alkylaminopropionic acid, N-alkyl iminodipropionic acid, imidazoline carboxylate, N-alkyl betaine, amidopropyl betaine, sarcosinate, amine oxide, sulfobetaine, sultain , Raulanhocarboxyglycinate, Raulanhopropionate, Stearanhoglycinate, Taroamphopropionate, Taroua Hoglycinate, Oreoamphoglycinate, Caproamphoglycinate, Caprylamphopropionate, Caprylamphocarboxyglycinate, Cocoylimidazoline, Laurylimidazoline, Stearylimidazoline, Behenylimidazoline, Behenylhydroxyethylimidazoline, Caprylamphopropylsulfonate Sulfonate, stearan propyl sulfonate, oleoamphopropyl sulfonate, their salts, and mixtures thereof are included. Among these, cocoamphopropionic acid or its sodium salt triethanolamine is preferable, and cocoamphopropionic acid sodium salt is more preferable.

  Specific examples of petroleum derivative surfactants include, for example, mineral oil, microcrystalline wax, distillate, and mixtures thereof.

  Among the above-mentioned surfactants, particularly preferred surfactants are laureth-4, PEG-2 dilaurate, stearic acid, sodium lauryl sulfate, dioctyl sodium sulfosuccinate, cocoamphopropionate, poloxamer 188, meloxapol 258, triethanolamine, dimethicone. , Polysorbate 60, sorbitan monostearate, polyoxyethylene hydrogenated castor oil, salts thereof, and mixtures thereof. By selectively using such a surfactant, foam breakage in the foam-like composition is further suppressed, and bubbles can be further stabilized.

<Solvent>
The solvent of the liquid composition is not particularly limited, but includes, for example, water; alcohols; polyols such as glycerin and 1,3-butanediol; oil classifications such as ester oil and liquid paraffin; Selected from the group consisting of The solvent preferably contains at least water.

<Acid>
In order to adjust the pH of the liquid composition, an acid can be added to the composition. The type of acid is not particularly limited, but the acid is acetic acid, acetylsalicylic acid, adipic acid, ascorbic acid, aspartic acid, benzoic acid, boric acid, carbonic acid, citric acid, formic acid, ethanesulfonic acid, fumaric acid, Glycerophosphoric acid, gluconic acid, glutaric acid, glycine, glyceric acid, glycolic acid, glutamic acid, hippuric acid, hydrochloric acid, lactic acid, maleic acid, malic acid, malonic acid, mandelic acid, methanesulfonic acid, mucinic acid, nitrous acid, oxalic acid , Pelargonic acid, phosphoric acid, propionic acid, saccharin, salicylic acid, sorbic acid, succinic acid, sulfuric acid, tartaric acid, thioglycolic acid, thiosulfuric acid, undecylenic acid, ethanolamine, natural and synthetic derived amino acids, their derivatives, and their It is preferably selected from the group consisting of mixtures. The pH of the liquid composition is preferably 2-10. In this case, it is possible to obtain an effect of further suppressing foam breakage of the foam-like composition and more easily maintaining the foam state of the composition. In order to further enhance this effect, the pH of the liquid composition is more preferably 3 to 9, and still more preferably 4 to 8.

<Cosmetic ingredients>
Moreover, it is preferable that a composition is cosmetics, and specifically, it is preferable to contain a cosmetic ingredient. In this case, the foam aerosol can obtain various effects derived from the cosmetic ingredients. Examples of such cosmetic ingredients include antioxidants. When it contains an antioxidant, the antioxidant effect of the foamy aerosol skin can be further enhanced. Antioxidants include, for example, vitamins A, vitamins B, vitamins C, vitamins D, vitamins E, amino acids, sulfur-containing organic compounds, carotenoids, furans, crude drugs, dibutylhydroxytoluene (ie, BHT) Butylhydroxyanisole (ie, BHA), astaxanthin, 1,4-diadicyclooctane, gallic acid esters, tannins, flavonoids and the like. Vitamin A, vitamin B, vitamin C, and vitamin D include not only vitamins but also derivatives and salts thereof. In addition, vitamin E includes not only vitamin E but also derivatives thereof. Further, the sulfur-containing organic compound includes not only a sulfur-containing organic compound but also a derivative or salt thereof. In addition, crude drugs include not only herbal medicines but also extracts thereof.

  Specific examples of vitamin A include, for example, retinol such as retinol, retinol palmitate, and retinol acetate; retinal and derivatives thereof; and dehydroretinal.

  Specific examples of vitamin B include, for example, thiamine and derivatives thereof; riboflavins such as riboflavin and riboflavin acetate; pyridoxines such as pyridoxine hydrochloride and pyridoxine dioctanoate; flavin adenine nucleotides, cyanocobalamin, folic acids, nicotinamide Nicotinic acids such as benzyl nicotinate; cholines; inositols; pantothenic acids such as calcium pantothenate, D-pantothenyl alcohol, pantothenyl ethyl ether, acetyl pantothenyl ethyl ether, and the like.

  Specific examples of vitamin C include, for example, L-ascorbic acid; L-ascorbyl palmitate, L-ascorbyl dipalmitate, L-ascorbyl isopalmitate, L-ascorbyl diisopalmitate, and L-ascorbyl tetraisopalmitate Ascorbyl, L-ascorbyl stearate, L-ascorbyl distearate, L-ascorbyl isostearate, L-ascorbyl diisostearate, L-ascorbyl myristate, L-ascorbyl dimyristic acid, L-ascorbyl isomyristate, diisomyristic acid Ascorbic acid alkyl esters such as L-ascorbyl, oleic acid L-ascorbyl, dioleic acid L-ascorbyl, 2-ethylhexanoic acid L-ascorbyl, di-2-ethylhexanoic acid L-ascorbyl; Ascorbic acid phosphates such as sodium corbate phosphate, potassium L-ascorbate phosphate, magnesium L-ascorbate phosphate, calcium L-ascorbate phosphate, aluminum L-ascorbate phosphate Ascorbic acid sulfate such as sodium L-ascorbate sulfate, potassium L-ascorbate sulfate, magnesium L-ascorbate sulfate, calcium L-ascorbate sulfate, aluminum L-ascorbate sulfate; L-ascorbine Ascorbates such as sodium acid, potassium L-ascorbate, magnesium L-ascorbate, calcium L-ascorbate, aluminum L-ascorbate; Colvin acid glucoside, ascorbic acid polypeptide, methylsilanol ascorbate, include ascorbyl tocopheryl potassium phosphate. Among these vitamin Cs, at least one of ascorbic acid phosphate salt and ascorbic acid glucoside is particularly preferable.

  Specific examples of vitamin D include, for example, cholecalciferol and ergocalciferol.

  Specific examples of vitamin E include, for example, tocopherols such as dl-α-tocopherol, dl-β-tocopherol, dl-γ-tocopherol, dl-δ-tocopherol; acetate-dl-α-tocopherol, nicotinic acid-dl -Tocopherol esters such as α-tocopherol, linoleic acid-dl-α-tocopherol, succinic acid dl-α-tocopherol; tocopherols such as tocopheres-5, tocopheres-10, and tocopheres-12; and ubiquinones . Among these vitamin Es, it should be at least one selected from the group consisting of dl-α-tocopherol, dl-β-tocopherol, dl-γ-tocopherol, dl-δ-tocopherol, and tocopherol esters. preferable.

  Specific examples of amino acids include, for example, histidine, tryptophan, alanine, and alkyl esters of alanine.

  Specific examples of the sulfur-containing organic compound include, for example, N-acetylcysteine, methionine, cysteine, homocysteine, glutathione, hypotaurine, cysteinsulfinic acid, cysteic acid, thiocysteine, taurine, thione taurine, diencholic acid, cystathionine, Sulfur-containing amino acids such as S-allyl cysteine, lenthionine, and ethionine, and sulfur-containing amino acid-containing compounds and intermediate metabolites thereof; dithiothreitol, thioglycerin, α-riboic acid are included.

  Specific examples of carotenoids include, for example, α-carotene, β-carotene, γ-carotene, lycopene, cryptoxanthine, zeaxanthin, isozeaxanthin, rhodoxanthin, capsanthin, and crocetin.

  Specific examples of furans include 2,5-dimethylfuran, 2-methylfuran, 2,5-diphenylfuran, and 1,3-diphenylisobenzofuran.

  Specific examples of herbal medicines include, for example, rosemary, sage, oregano, marjoram, thyme, wild thyme, clove, nutmeg, ginger, mugwort, pepper, pepper, brown mustard, dill, parsley, mint, laurel, perilla, basil, Turmeric, savory, maine, fenugreek, fennel, cumin, coriander, cinnamon, celery seed, cassia, caraway, cardamom, bay leaves, anise seed, allspice, carrot, melissa, yashajutsu, asenyaku, kawaragougi, fennel, vanilla, paprika , Yokuinin, Mokka, Suho, Curen, John Love, Ginkgo biloba, Green tea, Oolong tea, Black tea, Puard tea, Kombu, Wakame, Aonori, Nori, Ogon, Thyme, Psycho etc. It is. Among these herbal medicines, rosemary, sage, green tea, oolong tea, ougon, thyme, and psycho are particularly preferable. As these crude drugs, the crude drug itself can be used, or an extract can also be used.

  Among the above-mentioned antioxidants, at least one selected from the group consisting of vitamin Cs, vitamin Es, and herbal medicines is preferable. In this case, the antioxidant effect becomes more remarkable.

  The blending amount of the antioxidant is appropriately determined based on safety and antioxidant effect. For example, the content of the antioxidant in the liquid composition described above can be in the range of 0.0001 to 10.0% by mass.

  Moreover, the said composition can further contain a moisturizer, a ultraviolet absorber, a whitening agent, another medicinal component, etc. as a cosmetic ingredient.

  Specific examples of the humectant include, for example, polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, propylene glycol, dipropylene glycol, diglycerin, pyrrolidone carboxylic acid, sodium pyrrolidone carboxylate, Lactic acid, sodium lactate, maltose, D-mannitol, sodium chondroitin sulfate, sodium hyaluronate, sodium adenosine phosphate, glucosamine, cyclodextrin are included. As the humectant, at least one of these substances can be used.

  Specific examples of the ultraviolet absorber include, for example, benzoic acid ultraviolet absorbers such as paraaminobenzoic acid (hereinafter abbreviated as “PABA”), PABA ethyl, and PABA glyceryl; anthranilic acid ultraviolet absorbers such as methyl anthranilate; Salicylic UV absorbers such as octyl salicylate, phenyl salicylate, homomenthyl salicylate; isopropyl paramethoxycinnamate, octyl paramethoxycinnamate, 2-methoxyhexyl paramethoxycinnamate, mono-2-diparamethoxycinnamate Cinnamic acid UV absorbers such as glyceryl ethylhexanoate, [4-bis (trimethylsiloxy) methylsilyl-3-methylbutyl] -3,4,5-trimethoxycinnamate; 2,4-dihydroxybenzophenone, 2 -Hydroxy-4-methoxybenzopheno Benzophenone ultraviolet absorbers such as 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, sodium 2-hydroxy-4-methoxybenzophenone-5-sulfonate; urocanic acid, ethyl urocanate, 2-phenyl-5- Methylbenzoxazole, 2- (2′-hydroxy-5′-methylphenyl) benzotriazole, 4-tert-butyl-4′-methoxydibenzoylmethane are included. As the ultraviolet absorber, at least one of these substances can be used.

  Specific examples of the whitening agent include, for example, grabrizine, glabrene, liquiritin, isoliquiritin and licorice extract containing these, vitamin C and derivatives thereof, salts thereof, hydroquinone and derivatives thereof, salts thereof, cysteine and derivatives thereof and salts thereof , Resorcinols such as lucinol, glutathione, placenta extract, Clara extract, hawthorn extract, Yokuinin extract, Yukinoshita extract, cowberry extract, walnut extract, grape extract, chamomile extract, licorice extract, green tea extract Products and chimpi extract are included. As the whitening agent, at least one of these substances can be used.

Other medicinal ingredients include, for example, hormones such as estradiol and ethinylestradiol; amino acids such as arginine, aspartic acid, cystine, methionine, serine, leucine, and tryptophan; allantoin, azulene, glycyrrhetinic acid or derivatives thereof, glycyrrhizic acid ( Anti-inflammatory agents such as L-menthol, camphor, etc .; sulfur, lysozyme chloride, γ-oryzanol, hinokitiol, bisabolol, eucalptone, thymol, saikosaponin, carrot saponin, loofah saponin, muclodisaponin, etc. Saponins, yeast polysaccharides, carboxymethylated β-glucans and the like can be mentioned. As the medicinal component, at least one of these substances can be used.

Furthermore, various extracts having various medicinal ingredients can be blended into the composition. Specific examples of the extract include, for example, Dokudami extract, Oat extract, Merilot extract, Odorikosou extract, Peonies extract, Soybean extract, Loofah extract, Kina extract, Yukinoshita extract, Kakuhone extract, Fennel extract, Primrose extract, Rose extract, Giant extract, Lemon extract, shikon extract, aloe extract, ginger root extract, eucalyptus extract, horsetail extract, sage extract, thyme extract, tea extract, seaweed extract, cucumber extract, clove extract, raspberry extract, melissa extract, carrot extract, maroni extract, peach extract, There are peach leaf extract, mulberry extract, cornflower extract, clam extract, placenta extract, thymus extract, silk extract and so on.

  The composition further includes, for example, an oil component, a thickener, a water-soluble polymer, a film agent, a silicone resin having a three-dimensional network structure, a water-insoluble polymer such as silicone such as silicone rubber, and a polymer emulsion. , Powders, pigments, dyes, lakes, lower alcohols, sugars, organic acids, organic amines, sequestering agents, pH adjusters, antioxidants, antibacterial agents, preservatives, astringents, refreshing agents, fragrances, pigments, water And the like can be appropriately blended within a range that does not impair the effects of the present invention. As these additives, substances generally used in cosmetics can be appropriately used.

  The viscosity of the liquid composition is preferably 1 to 100,000 Pa · s. In this case, the composition sprayed from the pressure vessel becomes easier to foam. In addition, it is possible to increase the number of bubbles in the foam-like composition and to more easily hold the bubbles. The viscosity of the liquid composition is more preferably 10 to 10,000 Pa · s, and further preferably 100 to 5000 Pa · s. The viscosity of the liquid composition is controlled within the predetermined range by adjusting the amount of the polymer component contained in the composition or adjusting the amount of the above-described thickener added as necessary. can do. In addition, the viscosity of a composition is a viscosity in room temperature (specifically temperature 25 degreeC).

<Liquefied gas>
The foamy aerosol contains a liquefied gas filled in a pressure vessel. The liquefied gas exists as a liquid phase and a gas phase in the pressure vessel, and can play a role as a propellant. In the pressure vessel, the liquefied gas may be separated from the liquid composition or may be compatible. When the liquefied gas and the liquid composition are separated, at least two liquid phases exist in the pressure vessel.

  The liquefied gas is liquefied petroleum gas (hereinafter abbreviated as “LPG”), dimethyl ether (hereinafter abbreviated as “DME”), trans-1,3,3,3-tetrafluoropropane-1-ene (hereinafter referred to as “HFO”). -1234ze ") and at least one selected from the group consisting of carbon dioxide. In this case, a foam composition containing sufficient bubbles can be ejected from the foam aerosol.

  When at least one of LPG and DME is used as the liquefied gas, bubble breakage of the foam-like composition containing hydrogen in the bubbles is further suppressed, and the bubble state is more easily maintained. Further, when HFO-1234ze having a low environmental load and extremely low flammability and toxicity is used as a liquefied gas, it is possible to realize a foamed aerosol having a higher level of safety and environmental performance. In addition, when carbon dioxide is used as the liquefied gas, not only the function as a propellant but also the foamed composition after injection contains carbon dioxide, so that the blood circulation promoting effect of the skin is obtained by this carbon dioxide. . Among these liquefied gases, it is more preferable to use at least one of LPG and DME.

<Hydrogen>
The liquid aerosol contains hydrogen filled in a pressure vessel. Most of the hydrogen in the pressure vessel exists as a gas phase, but a part exists as a liquid phase. Hydrogen present as a liquid phase is present dissolved in at least one of a liquid composition and a liquefied gas. Hydrogen not only serves as a propellant for injecting a liquid-phase composition, but also exists in bubbles of the foam-like composition injected from the pressure-resistant container, and has a desired medicinal effect such as, for example, an effect of reducing active oxygen. Can play.

  The mass ratio of the mixture of the liquefied gas and hydrogen and the composition is preferably 1:99 to 90:10. In this case, when using the composition, it can be sprayed without leaving the composition. The mass ratio of the mixture to the composition is more preferably 2:98 to 80:20, and further preferably 5:95 to 70:30.

  The internal pressure ratio of the injection pressure of the liquefied gas and hydrogen is preferably 1: 9 to 99.9: 0.1. In this case, the composition can more easily maintain the foam state while increasing the amount of hydrogen contained in the foam-like composition ejected from the pressure-resistant container. In order to enhance the same effect, the mass ratio of the liquefied gas to hydrogen is more preferably 2: 8 to 99.5: 0.5, and further preferably 3: 7 to 99: 1. 5: 5 to 95: 5 is particularly preferable.

  The injection pressure of the foam aerosol at a temperature of 20 ° C. is preferably less than 1 MPa. In this case, the foamy composition is prevented from jumping out vigorously, and it becomes easy to form a continuous foamy composition. From the viewpoint of further improving the effect, the injection pressure is more preferably 0.97 MPa or less. The injection pressure is preferably 0.3 MPa or more. In this case, since the compatibility between hydrogen and the composition can be increased, the amount of hydrogen contained in the foam-like composition can be further increased. In order to further enhance this effect, the injection pressure is more preferably 0.5 MPa or more. The injection pressure can be measured by measuring the container internal pressure with a pressure gauge.

<Pressure vessel>
As the pressure vessel, a metal or glass vessel capable of preventing hydrogen leakage can be used. The pressure vessel preferably has a structure capable of preventing hydrogen leakage. The pressure vessel may have a single chamber structure or a double structure having an outer container and an inner container. In the case of a double-structured pressure vessel, the composition, hydrogen, and liquefied gas can be filled into the inner vessel. By adopting a double-structured container, hydrogen leakage from the pressure-resistant container can be further prevented.

  The pressure vessel can be provided with an injection port at an upper portion located on the opposite side of the vessel bottom. It is preferable to store the foamed aerosol in a state in which the injection port of the pressure vessel is directed downward in the vertical direction, that is, in a state where the bottom of the pressure vessel is directed upward in the vertical direction. In this case, hydrogen leakage from the pressure vessel can be further prevented.

  The foam-like aerosol can be used by jetting the foam-like composition from the pressure-resistant container in a state where the injection port of the pressure-resistant container is arranged downward in the vertical direction. The foam aerosol can be used by applying to the skin the foam-like composition containing hydrogen formed by spraying from a pressure-resistant container. Thereby, percutaneous absorption of hydrogen becomes possible and removal of active oxygen of skin cells becomes possible.

  EXAMPLES Hereinafter, although this invention is demonstrated more concretely based on an Example, this invention is not limited at all by the following example.

Example 1
The foamy aerosol of this example is demonstrated with reference to FIG.1 and FIG.2. As illustrated in FIG. 1, the foam aerosol 1 includes a pressure-resistant container 2, a liquid composition 3 filled in the pressure-resistant container 2, a liquefied gas 4, and hydrogen 5. The liquefied gas 4 exists as a liquid phase and a gas phase. Most of the hydrogen 5 exists as a gas phase, and a small amount is dissolved in the liquid phase. In FIG. 1, the composition 3 and the liquefied gas 4 are shown as one liquid phase. However, in the configuration of this example, the water phase composed of the composition 3 and the oil phase composed of the liquefied gas 4 are different from each other. It exists separately. In the gas phase, gaseous liquefied gas 4 and hydrogen 5 are mixed.

  In this example, as shown in Table 1 described later, a plurality of liquid compositions 3 having different compositions were prepared (see Formulation Examples 1 to 3). In addition, content of the water in a table | surface is the quantity (namely, remainder) for 100 mass parts of total amounts of a liquid composition.

  The pressure vessel 2 is a metal single-chamber container. A valve mechanism serving as an injection port 25 (also referred to as a discharge port) is provided at the upper portion of the pressure vessel 2. As such a valve mechanism, a mechanism known for foam aerosol can be employed. Preferably, a valve mechanism with sufficient gas leakage countermeasures is provided.

  Next, the manufacturing method of the foam aerosol 1 of this example is demonstrated. First, water and a surfactant were mixed to prepare a liquid composition 3 as shown in Table 1. This liquid composition 3 was filled in the pressure vessel 2 and further liquefied gas 4 and hydrogen gas 5 were filled. As the liquefied gas 4, liquefied petroleum gas (that is, LPG) was used. Table 1 shows the amount of the liquefied gas with respect to 100 parts by mass of the composition, the injection pressure of the foam aerosol at a temperature of 20 ° C., the partial pressure of the liquefied gas, and the partial pressure of hydrogen.

  The foamy aerosol 1 of this example has a liquid composition 3, a liquefied gas 4 for injecting the composition 3, hydrogen 5, and a pressure vessel 2 filled with these. In the foamed aerosol 1 having such a configuration, not only the liquefied gas 4 but also hydrogen 5 serves as a so-called propellant for ejecting the composition 3. As illustrated in FIG. 2, when the injection port 25 of the pressure-resistant vessel 2 is arranged vertically downward, the composition in the lower layer is formed by the gas phase in the upper layer (specifically, the vaporized liquefied gas 4 and hydrogen 5). The thing 3 is jetted from the jet nozzle 25 in a bubble shape. And hydrogen is hold | maintained in the bubble of the injected foam-like composition. Therefore, it becomes possible to supply hydrogen sufficiently to the skin by applying to the skin the foam composition ejected from the foam aerosol.

  The composition 3 contains at least a surfactant. Therefore, when the composition 3 is jetted from the foam aerosol 1, the composition 3 can be easily foamed and the foam state is easily maintained. Therefore, since the foam-like composition containing hydrogen can be hold | maintained on skin, it becomes possible to supply hydrogen sufficiently to skin. Moreover, a foam-like composition is excellent in a usability | use_condition. That is, since the foam-like composition is held on the skin, the user has a good feeling of familiarity with the skin, and a high permeation feeling can be obtained by foam stimulation or the like.

(Example 2)
This example is an example of a foam aerosol in which other cosmetic ingredients are blended in the composition. Specifically, the foamed aerosol was prepared in the same manner as in Example 1 except that vitamin Cs (specifically, sodium L-ascorbate phosphate) was further added to the liquid composition. Produced. Thereby, foamy aerosol can exhibit the antioxidant action derived from vitamin Cs. Other effects are the same as those of the first embodiment. In addition, as cosmetic ingredients, it is possible to contain ingredients other than the above-mentioned vitamin Cs. In the second and subsequent embodiments, the same reference numerals as those used in the first embodiment denote the same components as those in the first embodiment unless otherwise specified.

(Example 3)
This example is an example of a foam aerosol provided with a pressure-resistant container having a double structure. Specifically, as illustrated in FIG. 3, in the foamed aerosol 1 of the present example, the pressure-resistant container 2 includes an outer container 21 and an inner container 22 disposed inside thereof. The liquid composition 3, the liquefied gas 4, and the hydrogen 5 are filled in the inner container 22. The valve mechanism serving as the injection port 25 communicates with the inner container 22. Other configurations are the same as those of the first embodiment. In this example, since the pressure vessel 2 having a double structure is provided, leakage of hydrogen from the pressure vessel 2 can be further prevented. Other effects are the same as those of the first embodiment.

  As described above, according to the embodiment of the present invention, it is possible to supply hydrogen sufficiently to the skin, and it is possible to provide a foamy aerosol excellent in the feeling of familiarity and penetration into the skin. The present invention is not limited to the above-described embodiments, and can be combined with each other. Specifically, a composition further containing a cosmetic ingredient as in Example 3 may be filled into a double pressure-resistant container as in Example 3. Further, various modifications can be made without departing from the desired effect of the present invention.

DESCRIPTION OF SYMBOLS 1 Foam aerosol 2 Pressure-resistant container 3 Liquid composition 4 Liquefied gas 5 Hydrogen

Claims (10)

A liquid composition containing at least a surfactant;
A liquefied gas for injecting the composition;
A foamy aerosol filled with hydrogen and a pressure-resistant container.   The foamy aerosol according to claim 1, wherein the injection pressure at a temperature of 20 ° C is less than 1 MPa.   The foam aerosol according to claim 1 or 2, wherein a mass ratio of the mixture of the liquefied gas and the hydrogen and the composition is 40:60 to 90:10.   The foam aerosol according to any one of claims 1 to 3, wherein an internal pressure ratio of injection pressures of the liquefied gas and the hydrogen is 1: 9 to 99.9: 0.1.   The liquefied gas is at least one selected from the group consisting of liquefied petroleum gas, dimethyl ether, trans-1,3,3,3-tetrafluoropropane-1-ene, and carbon dioxide gas. The foamy aerosol according to any one of the above.   The foam aerosol of Claims 1-5 whose content of the said surfactant in the said composition is 0.01-50 mass%.   The foam aerosol according to any one of claims 1 to 6, wherein the composition is a cosmetic.   The foamy aerosol according to any one of claims 1 to 7, wherein the viscosity of the composition is 1 to 100,000 Pa · s.   The foamed aerosol according to any one of claims 1 to 8, wherein the foamed composition containing hydrogen formed by spraying from the pressure-resistant container is applied to the skin.   The foamed aerosol according to any one of claims 1 to 9, wherein the foamed composition is used by spraying the foamed composition from the pressure resistant container in a state where the injection port of the pressure resistant container is disposed vertically downward.

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