JP2017083340A5 - - Google Patents
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- JP2017083340A5 JP2017083340A5 JP2015212936A JP2015212936A JP2017083340A5 JP 2017083340 A5 JP2017083340 A5 JP 2017083340A5 JP 2015212936 A JP2015212936 A JP 2015212936A JP 2015212936 A JP2015212936 A JP 2015212936A JP 2017083340 A5 JP2017083340 A5 JP 2017083340A5
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- 238000005259 measurement Methods 0.000 claims 25
- 206010048259 Zinc deficiency Diseases 0.000 claims 24
- 238000007689 inspection Methods 0.000 claims 23
- 230000001264 neutralization Effects 0.000 claims 15
- HVYWMOMLDIMFJA-DPAQBDIFSA-N (3β)-Cholest-5-en-3-ol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 14
- HCHKCACWOHOZIP-UHFFFAOYSA-N zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 11
- 239000011701 zinc Substances 0.000 claims 11
- 229910052725 zinc Inorganic materials 0.000 claims 11
- 102000001554 Hemoglobins Human genes 0.000 claims 9
- 108010054147 Hemoglobins Proteins 0.000 claims 9
- 102100001249 ALB Human genes 0.000 claims 8
- 101710027066 ALB Proteins 0.000 claims 8
- 229940050528 albumin Drugs 0.000 claims 8
- 230000002950 deficient Effects 0.000 claims 8
- 229940107161 Cholesterol Drugs 0.000 claims 7
- VEXZGXHMUGYJMC-UHFFFAOYSA-M chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 7
- 235000012000 cholesterol Nutrition 0.000 claims 7
- 238000005534 hematocrit Methods 0.000 claims 7
- FKNQFGJONOIPTF-UHFFFAOYSA-N sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 claims 5
- 229910001415 sodium ion Inorganic materials 0.000 claims 5
- 210000002966 Serum Anatomy 0.000 claims 2
- 230000000875 corresponding Effects 0.000 claims 2
- 230000001276 controlling effect Effects 0.000 claims 1
Claims (18)
亜鉛濃度実測検査とは異なる検査項目の判定値を記憶する判定値記憶手段と、
前記検査項目の実測値を記憶する実測値記憶手段と、
亜鉛の欠乏状態であるか否かを推定する推定手段を備え,
前記検査項目には、検体検査に基づく検査項目である検体検査項目が含まれ、
前記推定手段は、前記実測値記憶手段に記憶された実測値のうち、1つ以上の検査項目において、前記判定値記憶手段に記憶された判定値よりも低いならば、亜鉛の欠乏状態であると推定する、亜鉛欠乏推定装置。 A zinc deficiency estimation device for estimating the state of zinc deficiency in serum,
Determination value storage means for storing determination values of inspection items different from the zinc concentration actual inspection,
An actual value storage means for storing an actual value of the inspection item;
An estimation means for estimating whether or not the zinc is deficient;
The test items include sample test items that are test items based on the sample test,
The estimation means is in a deficient state of zinc if it is lower than the determination value stored in the determination value storage means in one or more inspection items among the actual measurement values stored in the actual measurement value storage means. Estimating device for zinc deficiency.
前記特定項目における第2判定値である特定項目第2判定値を記憶する特定項目第2判定値記憶手段を備え、
前記実測値記憶手段は、前記特定項目の実測値である特定項目実測値を記憶する特定項目実測値記憶手段を備え、
前記特定項目第2判定値は、前記特定項目第1判定値よりも高いものであり、
前記推定手段は、
前記特定項目実測値が前記特定項目第1判定値未満の場合、
前記特定項目実測値が前記特定項目第1判定値以上かつ前記特定項目第2判定値未満の場合であって、前記特定項目以外の1つ以上の前記検査項目の実測値が判定値未満のとき、
又は、
前記特定項目実測値が前記特定項目第2判定値以上の場合であって、前記特定項目以外の2つ以上の前記検査項目の実測値が判定値未満のときに、亜鉛の欠乏状態であると推定する、請求項1から4のいずれかに記載の亜鉛欠乏推定装置。 A specific item first determination value storage means for storing a specific item first determination value that is a first determination value in the specific item of the inspection items;
A specific item second determination value storage means for storing a specific item second determination value that is a second determination value in the specific item;
The actual value storage means includes specific item actual value storage means for storing a specific item actual value that is an actual value of the specific item,
The specific item second determination value is higher than the specific item first determination value,
The estimation means includes
If the specific item actual measurement value is less than the specific item first determination value,
When the specific item actual measurement value is not less than the specific item first determination value and less than the specific item second determination value, and the actual measurement value of one or more of the inspection items other than the specific item is less than the determination value ,
Or
When the actual measurement value of the specific item is greater than or equal to the second determination value of the specific item, and when the actual measurement value of the two or more inspection items other than the specific item is less than the determination value, it is in a zinc deficient state The zinc deficiency estimation device according to any one of claims 1 to 4, wherein the estimation is performed.
前記特定項目は、前記中性脂肪濃度である、請求項5に記載の亜鉛欠乏推定装置。 The specimen test items are hemoglobin concentration, albumin concentration, and neutral fat concentration,
6. The zinc deficiency estimation device according to claim 5, wherein the specific item is the neutral fat concentration.
前記特定項目は、前記中性脂肪濃度である、請求項5に記載の亜鉛欠乏推定装置。 The specimen test items are hemoglobin concentration, total cholesterol concentration, neutral fat concentration, and chloride ion concentration,
6. The zinc deficiency estimation device according to claim 5, wherein the specific item is the neutral fat concentration.
前記特定項目は、前記中性脂肪濃度である、請求項5に記載の亜鉛欠乏推定装置。 The specimen test items are hemoglobin concentration, hematocrit, total cholesterol concentration, neutral fat concentration, and chloride ion concentration,
6. The zinc deficiency estimation device according to claim 5, wherein the specific item is the neutral fat concentration.
前記特定項目は、前記中性脂肪濃度であり、 The specific item is the neutral fat concentration,
前記推定手段は、 The estimation means includes
前記特定項目実測値が前記特定項目第1判定値未満の場合、 If the specific item actual measurement value is less than the specific item first determination value,
前記特定項目実測値が前記特定項目第1判定値以上かつ前記特定項目第2判定値未満の場合であって、前記特定項目以外の1つ以上の前記検査項目の実測値が判定値未満のとき、 When the specific item actual measurement value is not less than the specific item first determination value and less than the specific item second determination value, and the actual measurement value of one or more of the inspection items other than the specific item is less than the determination value ,
又は、 Or
前記特定項目実測値が前記特定項目第2判定値以上の場合であって、 When the specific item actual measurement value is equal to or greater than the specific item second determination value,
前記特定項目以外の2つ以上の前記検査項目の実測値が判定値未満のとき、 When the measured value of the two or more inspection items other than the specific item is less than the judgment value,
ヘモグロビン濃度の実測値が判定値未満のとき、 When the actual value of hemoglobin concentration is less than the judgment value,
若しくは、 Or
アルブミン濃度の実測値が判定値未満のときに、亜鉛の欠乏状態であると推定する、請求項5記載の亜鉛欠乏推定装置。 6. The zinc deficiency estimation device according to claim 5, wherein when the measured value of albumin concentration is less than the determination value, it is estimated that the state is zinc deficient.
前記特定項目は、前記中性脂肪濃度であり、 The specific item is the neutral fat concentration,
前記推定手段は、 The estimation means includes
前記特定項目実測値が前記特定項目第1判定値未満の場合、 If the specific item actual measurement value is less than the specific item first determination value,
前記特定項目実測値が前記特定項目第1判定値以上かつ前記特定項目第2判定値未満の場合であって、前記特定項目以外の1つ以上の前記検査項目の実測値が判定値未満のとき、 When the specific item actual measurement value is not less than the specific item first determination value and less than the specific item second determination value, and the actual measurement value of one or more of the inspection items other than the specific item is less than the determination value ,
又は、 Or
前記特定項目実測値が前記特定項目第2判定値以上の場合であって、 When the specific item actual measurement value is equal to or greater than the specific item second determination value,
前記特定項目以外の2つ以上の前記検査項目の実測値が判定値未満のとき、 When the measured value of the two or more inspection items other than the specific item is less than the judgment value,
若しくは、 Or
ヘマトクリットの実測値が判定値未満のときに、亜鉛の欠乏状態であると推定する、請求項5記載の亜鉛欠乏推定装置。 6. The zinc deficiency estimation device according to claim 5, wherein when a measured value of hematocrit is less than a determination value, it is estimated that the state is zinc deficient.
前記特定項目は、前記中性脂肪濃度であり、 The specific item is the neutral fat concentration,
前記推定手段は、 The estimation means includes
前記特定項目実測値が前記特定項目第1判定値未満の場合、 If the specific item actual measurement value is less than the specific item first determination value,
前記特定項目実測値が前記特定項目第1判定値以上かつ前記特定項目第2判定値未満の場合であって、前記特定項目以外の1つ以上の前記検査項目の実測値が判定値未満のとき、 When the specific item actual measurement value is not less than the specific item first determination value and less than the specific item second determination value, and the actual measurement value of one or more of the inspection items other than the specific item is less than the determination value ,
又は、 Or
前記特定項目実測値が前記特定項目第2判定値以上の場合であって、 When the specific item actual measurement value is equal to or greater than the specific item second determination value,
前記特定項目以外の2つ以上の前記検査項目の実測値が判定値未満のとき、 When the measured value of the two or more inspection items other than the specific item is less than the judgment value,
若しくは、 Or
アルブミン濃度の実測値が判定値未満のときに、亜鉛の欠乏状態であると推定する、請求項5記載の亜鉛欠乏推定装置。 6. The zinc deficiency estimation device according to claim 5, wherein when the measured value of albumin concentration is less than the determination value, it is estimated that the state is zinc deficient.
前記特定項目は、前記中性脂肪濃度である、請求項5記載の亜鉛欠乏推定装置。 6. The zinc deficiency estimation device according to claim 5, wherein the specific item is the neutral fat concentration.
前記項目比較手段による比較結果に基づいて、前記検査項目のそれぞれにおいて、項目点数を決定する決定手段と、 Determination means for determining an item score in each of the inspection items based on a comparison result by the item comparison means;
前記検査項目のそれぞれの項目点数を加算して合計点数を算出する算出手段と、 A calculation means for calculating the total score by adding the item scores of each of the inspection items;
前記合計点数に対応し、亜鉛の欠乏状態であるか否かを推定する分岐点となる最終判定点数を記憶する最終判定点数記憶手段と、 Corresponding to the total score, a final determination score storage means for storing a final determination score that becomes a branch point for estimating whether or not the zinc deficiency state;
前記合計点数と前記最終判定点数とを比較する点数比較手段とを備え、 A score comparison means for comparing the total score and the final determination score;
前記推定手段は、前記点数比較手段の比較結果に基づいて、亜鉛の欠乏状態であると推定する、請求項1から12のいずれかに記載の亜鉛欠乏推定装置。 13. The zinc deficiency estimation device according to claim 1, wherein the estimation means estimates that the state is a zinc deficiency based on a comparison result of the score comparison means.
亜鉛濃度実測検査とは異なる検査項目の判定値を表示させる判定値表示手段と、 Judgment value display means for displaying the judgment value of the inspection item different from the zinc concentration actual inspection,
前記検査項目のそれぞれについて、実測値が前記判定値以上であるか否かの入力を受け付ける入力受付手段と、 For each of the inspection items, an input receiving means for receiving an input as to whether or not an actual measurement value is greater than or equal to the determination value;
亜鉛の欠乏状態であるか否かを推定する分岐点となる最終判定点数を記憶する最終判定点数記憶手段と、 A final judgment score storage means for storing a final judgment score as a branch point for estimating whether or not the zinc is deficient;
亜鉛の欠乏状態を推定する推定手段を備え、 An estimation means for estimating a zinc deficiency state;
前記検査項目には、検体検査に基づく検査項目である検体検査項目が含まれ、 The test items include sample test items that are test items based on the sample test,
前記推定手段は、前記入力受付手段に入力された入力内容と前記最終判定点数に基づいて亜鉛の欠乏状態であるか否かを推定する、亜鉛欠乏推定装置。 The said estimation means is a zinc deficiency estimation apparatus which estimates whether it is a zinc deficiency state based on the input content input into the said input reception means, and the said last determination score.
前記印刷装置に、請求項1から15のいずれかに記載の推定手段による推定結果を印刷させる推定結果印刷制御手段として機能させるためのプログラム。 16. A program for causing the printing apparatus to function as an estimation result printing control unit that causes an estimation result according to any one of claims 1 to 15 to be printed.
亜鉛濃度実測検査とは異なる検査項目の判定値を記憶する判定値記憶手段と、 Determination value storage means for storing determination values of inspection items different from the zinc concentration actual inspection,
前記検査項目のそれぞれに対応する実測値を記憶する実測値記憶手段と、 Actual value storage means for storing actual values corresponding to each of the inspection items;
亜鉛の欠乏状態であるか否かを推定する推定手段として機能させるためのプログラムであって、 A program for functioning as an estimation means for estimating whether or not a zinc deficiency state,
前記検査項目には、検体検査に基づく検査項目である検体検査項目が含まれ、 The test items include sample test items that are test items based on the sample test,
前記推定手段は、前記実測値記憶手段に記憶された実測値のうち、1つ以上の前記検査項目において、前記判定値記憶手段に記憶された判定値よりも低いならば、亜鉛の欠乏状態であると推定する、プログラム。 In the one or more inspection items among the actual measurement values stored in the actual measurement value storage unit, the estimation unit is in a zinc deficient state if it is lower than the determination value stored in the determination value storage unit. A program that presumes to be.
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JP2017083340A JP2017083340A (en) | 2017-05-18 |
JP2017083340A5 true JP2017083340A5 (en) | 2017-08-03 |
JP6421398B2 JP6421398B2 (en) | 2018-11-14 |
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EP3751473A4 (en) * | 2018-02-09 | 2021-12-08 | Axion Research Inc. | System that estimates state of complex system to be inspected |
JP2020193852A (en) * | 2019-05-28 | 2020-12-03 | 株式会社ファンケル | Non-invasive method for estimating serum zinc value |
JP7379767B2 (en) | 2019-09-17 | 2023-11-15 | 株式会社ファンケル | Non-invasive method for estimating serum zinc levels |
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IL61080A0 (en) * | 1980-09-19 | 1980-11-30 | Garfinkel D | Pharmaceutical composition containing zinc ions |
EP1970452A4 (en) * | 2005-12-27 | 2009-06-17 | Univ Nihon | Method of examining zinc-deficient taste disturbance |
WO2011066527A1 (en) * | 2009-11-30 | 2011-06-03 | The Ohio State University | Zinc status biomarker materials and related methods |
US20130295692A1 (en) * | 2010-12-23 | 2013-11-07 | Metanomics Health Gmbh | Means and methods for predicting diabetes |
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