JP2017056017A - Connector for bag for sealing therein blood product heat/cold insulation agent, blood product heat/cold insulation tool, and blood product heat/cold insulation method using the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a connector for a bag for sealing therein a blood product heat/cold insulation agent to comparatively simply form a housing space capable of holding a blood product at a proper temperature, with a degree of high freedom.SOLUTION: A connector 10 for a bag for sealing therein a blood product heat/cold insulation agent comprises a connection part 14 which is detachably attached to each bag for sealing therein a blood product heat/cold insulation agent and interconnects the peripheries of the plural bags attachably and detachably.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a connector for a blood product heat-retaining / cooling agent-enclosed bag, a blood product heat-retaining / cooling device, and a heat-retaining / cooling method using the same, and more specifically, a plurality of blood product heat-reserving / cooling agents using the connection device. The present invention relates to a technique for connecting sealed bags.

  Blood products such as blood for transfusion and plasma fractionated products have different storage temperatures depending on the types. In blood for transfusion, whole blood preparations and erythrocyte component preparations are stored at 2-6 ° C., platelet component preparations are stored at 20-24 ° C., and plasma preparations are stored at −20 degrees or less. In the plasma fraction preparation, the albumin preparation is kept at room temperature, and the immunoglobulin preparation is kept at 10 ° C. or lower. Blood for transfusion is usually enclosed in a bag-like airtight container and is required to be stored as a blood bag (or separation bag) at an appropriate temperature.

  When storing a blood product in a place where a refrigerator or a freezer is not prepared or transporting the blood product, it is required to keep the temperature and temperature at an appropriate temperature using a heat and cold insulation agent. When storing or transporting whole blood preparations and erythrocyte component preparations, they have been kept at a low temperature using a cryogen or the like.

  As the cryogen, for example, a mixture of water, ammonium chloride and sodium carbonate has been used. However, the temperature may be too low during low-temperature storage with a cryogen. Further, the temperature may increase depending on the outside air temperature, and it may be difficult to maintain an appropriate temperature.

  Therefore, a heat and cold insulation agent for maintaining the most suitable temperature according to the type of blood product has been developed regardless of the storage conditions and the transport state. For example, Patent Document 1 discloses a cold insulating agent containing polyethylene glycol as a component by the present applicant.

JP-A-10-192366 International Publication No. 2014/125878

  Conventionally, when storing and transporting a blood bag at an appropriate temperature, as described in, for example, Patent Document 1 described above, the blood bag is sandwiched with a cushion-type heat insulating material in a main body container having heat insulation properties. There were many. In this aspect, there are obtained an advantage that the temperature of the blood bag and the heat insulating material can be controlled easily, and an advantage that it can be stored compactly without being bulky. However, most of the surface of the blood bag is covered with a heat insulating material.

  It is desirable that the blood product can exchange gas with the outside air through the surface of the blood bag. The blood bag container is usually made of a material having a certain degree of gas permeability, such as polyvinyl chloride (PVC) or polyolefin (PO). In particular, a PO-type container excellent in gas permeability is used for storage of concentrated platelet (PC) preparations. This is because oxygen deficiency is eliminated by gas exchange with the outside, and a decrease in pH due to lactic acid production is suppressed to prevent a decrease in platelet function.

  Patent Document 2 discloses a constant temperature storage and transport container for maintaining medicines, specimens, and the like that require temperature management within a predetermined temperature range. The container described in Patent Document 2 is formed in a box shape by combining plate materials (heat insulating materials), and has a configuration in which a recess for accommodating a regenerator material is provided inside a side wall formed by the plate material. If such a box-shaped container is used, the surface of the blood bag to be accommodated is not entirely covered, so that an improvement in gas exchange can be expected.

  However, in the container described in Patent Document 2, it is necessary to assemble a plurality of plate materials according to a predetermined procedure, and to attach the regenerator material to the recesses provided in each plate material so as not to fall off. For this reason, there is a problem that it takes time to prepare the container. Further, since the container described in Patent Document 2 has a bulky shape and a constant volume, for example, when a small amount of blood bag is transported, there is a problem that convenience is lowered due to being too large. It was.

  The present invention has been made in order to solve the above-described problems, and is used for a blood product heat-retaining and cooling agent-enclosed bag for forming a storage space capable of holding a blood product at an appropriate temperature relatively easily with a high degree of freedom. The purpose is to provide a connector.

  The connector for a blood product heat-retaining / cooling agent-enclosed bag according to an embodiment of the present invention is detachably attached to the blood product heat-retaining / cooling agent-enclosed bag and removably connects the peripheral portions of a plurality of blood product heat-retaining / cooling agent-enclosed bags The connecting part is provided.

  In one embodiment, the peripheral part of the blood product heat-retaining / cooling agent-enclosed bag includes two peripheral parts facing each other across the central part of the blood product heat-retaining / cooling agent-enclosed bag, When mounted, the connecting portion at least partially covers each of the two peripheral portions.

  In one embodiment, the blood product heat-retaining / cooling agent-enclosed bag has a flat rectangular shape having four sides, and when the blood product heat-retaining / cooling agent-enclosed bag is attached, the connecting portion corresponds to the four sides. Each of the four peripheral portions is at least partially covered.

  In one embodiment, the connecting portion is formed in a frame shape including four linear portions extending along the four sides.

  In one embodiment, the connector has a bag-like form that can accommodate the blood product heat-retaining / cooling agent-enclosed bag.

  In one embodiment, the connecting portion is opaque, and is provided so as not to cover a central portion of the blood product heat-retaining / cooling agent-enclosed bag when attached to the blood product heat-retaining / cooling agent-enclosed bag. The central part of the cold-insulating bag is visible.

  In one embodiment, the connecting portion includes a hook-and-loop fastener.

  A blood product heat and cold insulation device according to an embodiment of the present invention includes any one of the above blood product heat and cold agent-enclosed bag connector and the blood product heat and cold agent encapsulated bag connector. An enclosing bag.

  According to an embodiment of the present invention, there are provided a blood product heat insulation cooler step of preparing a plurality of the above blood product heat insulation cooler, a step of three-dimensionally assembling a plurality of blood product heat insulation cooler via the connecting portion, And a step of accommodating a container in which the blood product is sealed in a space surrounded by a plurality of three-dimensionally assembled blood product heat insulation and cooling tools.

  According to the embodiment of the present invention, since the peripheral portions of a plurality of blood product heat-retaining / cooling agent-enclosed bags (heat insulation materials) are detachably connected using the attached connector, the accommodation space surrounded by the heat insulation materials Can be formed relatively easily with a high degree of freedom. By storing the blood product (blood bag) in the storage space, it can be stored and transported while maintaining an appropriate temperature with good gas exchangeability.

(A) is a perspective view which shows the coupling tool by embodiment of this invention, (b) is a perspective view which shows a thermal insulation cold storage agent enclosure bag (thermal insulation material). (A) is a perspective view which shows the state which mounted | wore the heat insulating material shown in FIG.1 (b) with the coupling tool shown to Fig.1 (a), (b) is along the AA 'line of (a). FIG. It is a perspective view which shows an example of the state which connected the some of the connection tool which accommodated the heat insulating material shown in FIG. 2 by the connection part. It is a perspective view which shows 1 aspect which accommodates the some of the connection heat retention material shown in FIG. 3 in a heat insulation container. (A) is the top view and sectional drawing which show the coupler of another embodiment of this invention, (b) and (c) are top views which show another embodiment.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings, but the present invention is not limited to the following embodiments.

  Fig.1 (a) is a typical perspective view of the coupling tool 10 by embodiment of this invention, FIG.1 (b) is the thermal insulation cooler enclosure bag 20 (henceforth a heat insulating material hereafter) with which the coupling tool 10 is mounted | worn. It is a typical perspective view of (or a cold storage material) or a heat storage material (or a cold storage material). 2A is a perspective view showing a state in which the connector 10 is attached to the heat insulating material 20, and FIG. 2B is a cross-sectional view taken along the line AA ′ in FIG. FIG.

  As shown in FIG. 1 (a), the connector 10 of the present embodiment has a rectangular bag shape with a lid that can be opened and closed, and more specifically, on the periphery of the rectangular transparent bag 12. It has a structure in which a hook-and-loop fastener as the connecting portion 14 is attached in a frame shape.

  The transparent bag 12 may be formed from various resin materials such as polyethylene, nylon (polyamide), polypropylene, and polyethylene terephthalate (PET). Moreover, as a surface fastener which comprises the connection part 14, the well-known various thing which can be attached or detached in surface can be used. For example, when a general hook-and-loop fastener that is fixed by coupling a hook and a loop is used, a hook surface may be attached to one surface of the transparent bag 12 and a loop surface may be attached to the other surface of the transparent bag 12. . Further, when a hook-and-loop fastener of the type in which the hook surface and the loop surface are not distinguished and the hook and loop are provided on the same surface is used, it may be attached to one or both surfaces of the transparent bag 12. The hook-and-loop fastener may be fixed to the transparent bag 12 by sewing, for example, or may be fixed by adhesion using a double-sided tape or the like.

  The connecting portion 14 formed of such a hook-and-loop fastener includes four linear portions extending along the four sides of the bag 12 and is formed in a frame shape. The connecting portion 14 is preferably provided so as to include at least two linear portions 141 and 142 facing each other with a gap therebetween.

  Moreover, the heat insulating material 20 has a planar rectangular shape as shown in FIG. 1B, and is accommodated in the connector 10 with the lid 10a opened. For this reason, the transparent bag 12 of the connector 10 described above is designed to have a size that is slightly larger than the planar rectangular heat insulating material 20. As described above, in this embodiment, the heat insulating material 20 is accommodated in the connector 10, but in this specification, this is expressed as detachably mounting the connector 10 on the heat insulating material 20. is there.

  Although it does not specifically limit as the heat insulating material 20, For example, the brand name "PC Conster" currently sold by the present applicant can be used. Although the temperature range to be maintained varies depending on the use, the heat insulating material 20 is preferably maintained at a temperature of, for example, 20 to 24 ° C. for a long time when used for storage and transportation of platelet preparations.

  As shown in FIG. 2A, after the heat insulating material 20 is accommodated, the cover 10 a of the connector 10 is closed to prevent the heat insulating material 20 from being detached from the connector 10. In the present embodiment, a hook-and-loop fastener 14a (FIG. 1A) is also provided on the inner surface of the lid 10a, and is fixed to the hook-and-loop fastener provided on the bag side when the lid 10a is closed. Moreover, in the connector 10, the hook_and_loop | surface fastener 14b (FIG.2 (a)) is attached also to the back side of the lid | cover 10a, and the hook-and-loop fastener 14b comprises a part of connection part 14 in the state which closed the lid | cover 10a. .

  By attaching the connector 10 to the heat insulating material 20 (here, the heat insulating material 20 is accommodated in the connector 10 and the lid 10a is closed), the blood product heat insulating cooler 1 shown in FIG. 2A is obtained. In the blood product heat insulating cooler 1 configured as described above, the peripheral portion of the heat insulating material 20 is covered by the connecting portion 14 of the connecting tool 10 as shown in FIG.

  In addition, the connection part 14 may be provided in the various aspects, as long as the peripheral parts of the heat insulating material 20 can be connected so that attachment or detachment is possible. The connecting portion 14 is preferably a portion that at least partially covers two peripheral portions facing each other across the central portion of the heat insulating material 20 when attached to the heat insulating material 20 (for example, in FIG. 2B). The linear portions 141 and 142) shown in FIG. More specifically, the connecting portion 14 is preferably provided so as to at least partially cover each of the four peripheral portions corresponding to the four sides of the heat insulating material 20. FIG. 2B shows a form in which the connecting portion 14 is provided on both side surfaces of the transparent bag 12 so as to sandwich the peripheral edge portion of the heat insulating material 20 from both sides. It may be provided only on one surface of the transparent bag 12 so as to overlap with the peripheral edge portion.

  In the connector 10 described above, the connecting portion 14 is opaque. However, the connection part 14 is provided so that the heat insulation bag 20 may not cover a center part, when the heat insulation bag 20 is mounted | worn. For this reason, the center part of the heat insulation bag 20 can be visually recognized from the outside, and the state of the heat insulation material 20 can be confirmed from the outside.

  FIG. 3 shows a state in which four blood product heat-retaining / retaining tools 1 (connector 10 and heat-retaining material 20) are prepared and connected so as to form an enclosure via the connecting part 14. The connection part 14 is used in order to connect the peripheral parts of the heat insulating material 20 so that attachment or detachment is possible, and makes it possible to arrange a plurality of blood product heat insulation cooler 1 in three dimensions. The three-dimensionally arranged blood product heat insulation cooler 1 constitutes a heat insulation cooler unit 1A that forms an accommodation space.

  A blood bag 3 is accommodated in the space surrounded by the blood product heat insulating and cooler 1. In this way, the blood bag 3 can be stored in a state surrounded by the plurality of blood product heat insulating coolers 1. Since the blood bag 3 is surrounded by the blood product heat insulation cooler 1 with a gap therebetween, sufficient gas exchange is ensured.

  FIG. 4 shows a state in which a plurality of heat insulating and cooler units 1A are accommodated in a heat insulating container 5 formed of a heat insulating material such as polystyrene foam or phenol resin foam. The blood bag 3 shown in FIG. 3 is accommodated in the accommodation space of each heat insulation and cooler unit 1A. In this way, it is possible to maintain the plurality of blood bags 3 at an appropriate temperature for a long time with good gas exchangeability.

  In addition, 1 A of heat insulation cooler units shown in FIG. 3 are only an illustration, and it is possible to comprise arbitrary solids by connecting the several blood product heat insulation cooler 1. For example, a plurality of blood product heat insulation coolers 1 arranged vertically are provided so as to be arranged in a line with a gap, and another blood product heat insulation cooler 1 is connected to both sides of the row at a 90 ° angle by a ladder. It is good also as an aspect (form in which a slot is located in a line). In this configuration, three or more blood product heat insulation coolers constituting a row may be arranged between a pair of blood product heat insulation coolers arranged on both sides. In this embodiment, a plurality of blood bags can be accommodated so as to lean against each slot.

  The plurality of blood product heat insulation coolers are connected not only by the linear connecting portions 14 extending along the side of the heat insulating material, but also by connecting the central portion of one heat insulating material and the side of the other heat insulating material. It may be combined in a T shape as shown. When a plurality of stages are used, a lid and a bottom plate may be provided on the upper and lower sides of the enclosure by the blood product heat insulation cooler by another blood product heat insulation cooler. Further, when a plurality of storage spaces are provided as shown in FIG. 4, only one common blood product heat insulating cooler may be provided between adjacent storage spaces.

  The blood product heat insulating cooler 1 according to the present embodiment described above can be prepared by a relatively simple procedure, and a plurality of parts can be easily assembled into an arbitrary three-dimensional body using the connecting portion 14. Therefore, the storage space for the blood bag can be formed relatively easily with a high degree of freedom.

  Moreover, the blood product heat insulation cooler 1 can be stored separately, without connecting, when not in use. Therefore, it is convenient for storage and carrying. Moreover, since the connector 10 can be removed from the heat insulating material 20, there is no inconvenience when it is desired to use the heat insulating material 20 alone. The connector 10 may be attached to the heat insulating material 20 only when necessary, and many can be stored together at other times.

  FIG. 5A is a view showing a connector 10A according to another embodiment, in which the upper side in the drawing is a plan view, and the lower side in the drawing is a cross-sectional view along the line B-B ′. This embodiment differs from the connector 10 shown in FIG. 1A in that the connector 10 </ b> A is configured only by a frame member having the connecting portion 14 without using a transparent bag. The frame-shaped connector 10A may be formed thicker than the width of the connecting portion 14 of the embodiment shown in FIG. 1 so that the heat insulating material is not easily dropped. Further, in the connector 10A, the opening for accommodating the heat insulating material 20 and the lid 10a for closing the opening are provided only on the upper side. However, the present invention is not limited to this, and three sides can be separated. The aspect in which the flap) was provided may be sufficient. In this case, after mounting the heat insulating material on the frame member on one side in a state where the coupling tool is opened, the other frame member is folded in two so as to overlap, and the three-side flaps are closed to attach the heat insulating material. be able to.

  FIG. 5B shows a connector 10B according to still another embodiment. The connector 10B has an octagonal frame shape. In this configuration, the connecting portion 14 is provided so as to partially cover the four sides of the heat insulating material 20. Even if it is such an aspect, the peripheral part of the heat insulating material 20 can be connected and a solid can be formed in the state which mounted | wore with the connector 10B. Further, since the connector 10B is configured so as to pass inside the four corners of the heat insulating material 20, there is an advantage that the heat insulating material 20 is difficult to be detached from the connector 10B.

  FIG. 5C shows a connector 10C according to still another embodiment. 10 C of coupling tools are comprised so that the front and back of the heat insulating material 20 may be covered in the cross shape which passes along the center part of the heat insulating material 20 when mounted | worn. Also in the connector 10C, the linear connecting portion 14 is provided so as to partially cover the four sides of the heat insulating material 20, and the peripheral portions of the heat insulating material 20 can be connected to each other. Further, the connector 10C can be attached to the heat insulating material 20 relatively easily, and effectively prevents the heat insulating material 20 from being detached.

  While the embodiments of the present invention have been described above, various modifications can be made. For example, although the aspect which uses a hook_and_loop | surface fastener as the connection part 14 was demonstrated above, it is not restricted to this. The connection part 14 may be comprised from the zipper, the snap button, etc. Moreover, the connection part 14 is not restricted to what is provided in a linear form, For example, when attached to the heat insulating material 20, it may be provided in the island-like aspect along with the peripheral part of the heat insulating material 20. As shown in FIG.

  The connector according to the embodiment of the present invention is preferably used by being attached to a blood product heat-retaining / cooling agent-enclosed bag for storing and transporting the blood product at an appropriate temperature.

DESCRIPTION OF SYMBOLS 1 Blood product heat insulation cooler 1A Thermal insulation cooler unit 3 Blood bag 5 Heat insulation container 10 Connection tool 10a Lid 12 Transparent bag 14 Connection part 20 Heat insulation material

Claims (9)

  A connector for a blood product heat-retaining / cooling agent-enclosed bag, comprising a connecting part that is detachably attached to the blood product heat-retaining / cooling agent-enclosed bag and removably connects the peripheral portions of the plurality of blood product heat-retaining / cooling agent-enclosed bags.   When the peripheral part of the blood product heat-retaining / cooling agent-enclosed bag includes two peripheral parts facing each other across the central part of the blood product heat-retaining / cooling agent-enclosed bag, The connector for a blood product heat-retaining / cooling agent-enclosed bag according to claim 1, wherein the connecting portion at least partially covers each of the two peripheral portions.   The blood product heat-retaining / cooling agent-enclosed bag has a planar rectangular shape having four sides, and when the blood product heat-retaining / cooling agent-enclosed bag is attached to the blood product heat-retaining / cooling agent-enclosed bag, the connecting portion has four peripheral portions corresponding to the four sides. The connector for a blood product heat-retaining / cooling agent-enclosed bag according to claim 2, wherein each of the at least partly covers each of the two.   The said connection part is a connector for blood product heat insulating and cold agent enclosure bags of Claim 3 currently formed in the frame shape containing four linear parts extended along the said 4 sides.   The connector for a blood product heat-retaining / cooling agent-enclosed bag according to any one of claims 1 to 4, having a bag-like form capable of accommodating the blood product heat-retaining / cooling agent-enclosed bag.   The connecting portion is opaque, and is provided so as not to cover a central portion of the blood product heat-retaining and cooling agent-enclosed bag when attached to the blood product heat-retaining and cooling agent-enclosed bag. The heat insulating cooler according to any one of claims 1 to 5, wherein the central portion is visible.   The connector for a blood product heat-retaining / cooling agent-containing bag according to any one of claims 1 to 6, wherein the connecting portion includes a hook-and-loop fastener.   A blood product comprising: the blood product heat-retaining / cooling agent-enclosed bag connector according to any one of claims 1 to 7; and a blood product heat-retaining / cooling agent-enclosed bag to which the blood product heat-retaining / cooling agent-enclosed bag connector is attached. Thermal insulation cooler. A step of preparing a plurality of blood product heat insulation and cooling devices according to claim 8;
A step of three-dimensionally assembling a plurality of blood product heat-retaining / cooling devices via the connecting portion;
Storing a blood product sealed container in a space surrounded by the three-dimensionally assembled blood product heat insulating cooler.

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