JP2016540798A5 - - Google Patents
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- Publication number
- JP2016540798A5 JP2016540798A5 JP2016540038A JP2016540038A JP2016540798A5 JP 2016540798 A5 JP2016540798 A5 JP 2016540798A5 JP 2016540038 A JP2016540038 A JP 2016540038A JP 2016540038 A JP2016540038 A JP 2016540038A JP 2016540798 A5 JP2016540798 A5 JP 2016540798A5
- Authority
- JP
- Japan
- Prior art keywords
- opioid
- active ingredient
- pharmacologically active
- nsaid
- cox
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002831 pharmacologic agent Substances 0.000 description 10
- 230000000202 analgesic effect Effects 0.000 description 6
- 229940111134 coxibs Drugs 0.000 description 6
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 description 6
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 6
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13197503.9 | 2013-12-16 | ||
| EP13197503 | 2013-12-16 | ||
| PCT/EP2014/077748 WO2015091352A1 (en) | 2013-12-16 | 2014-12-15 | Tamper resistant dosage form with bimodal release profile manufactured by co-extrusion |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019107622A Division JP2019172688A (ja) | 2013-12-16 | 2019-06-10 | 共押出により製造される、二峰性放出プロファイルを有する改変防止(tamper resistant)剤形 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016540798A JP2016540798A (ja) | 2016-12-28 |
| JP2016540798A5 true JP2016540798A5 (enExample) | 2018-12-06 |
Family
ID=49882823
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540038A Pending JP2016540798A (ja) | 2013-12-16 | 2014-12-15 | 共押出により製造される、二峰性放出プロファイルを有する改変防止(tamper resistant)剤形 |
| JP2019107622A Withdrawn JP2019172688A (ja) | 2013-12-16 | 2019-06-10 | 共押出により製造される、二峰性放出プロファイルを有する改変防止(tamper resistant)剤形 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019107622A Withdrawn JP2019172688A (ja) | 2013-12-16 | 2019-06-10 | 共押出により製造される、二峰性放出プロファイルを有する改変防止(tamper resistant)剤形 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20150164807A1 (enExample) |
| EP (1) | EP3082781A1 (enExample) |
| JP (2) | JP2016540798A (enExample) |
| AU (1) | AU2014365038B2 (enExample) |
| CA (1) | CA2933983A1 (enExample) |
| MX (1) | MX2016007848A (enExample) |
| WO (1) | WO2015091352A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201502077D0 (en) * | 2015-02-09 | 2015-03-25 | Cubic Pharmaceuticals Ltd And Delta Pharmaceuticals Ltd | Improved hme technology |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3612211A1 (de) | 1986-04-11 | 1987-10-15 | Basf Ag | Kontinuierliches verfahren zum tablettieren |
| DE19710008A1 (de) * | 1997-03-12 | 1998-09-17 | Basf Ag | Feste, mindestens zweiphasige Zubereitungsformen eines Opioid-Analgeticums mit verzögerter Freisetzung |
| AU3024399A (en) | 1998-04-03 | 1999-10-25 | Bm Research A/S | Controlled release composition |
| US7141250B2 (en) | 2001-08-06 | 2006-11-28 | Euro-Celtique S.A. | Pharmaceutical formulation containing bittering agent |
| WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
| DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| ES2307003T3 (es) | 2003-03-26 | 2008-11-16 | Egalet A/S | Composiciones matriciales para el suministro controlado de sustancias medicamentosas. |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| WO2005016313A1 (de) | 2003-08-06 | 2005-02-24 | Grünenthal GmbH | Gegen missbrauch gesicherte darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE10360792A1 (de) | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| WO2005102286A1 (de) | 2004-04-22 | 2005-11-03 | Grünenthal GmbH | Verfahren zur herstellung einer gegen missbrauch gesicherten, festen darreinchungsform |
| WO2006002883A1 (de) | 2004-07-01 | 2006-01-12 | Grünenthal GmbH | Verfahren zur herstellung einer gegen missbrauch gesicherten, festen darreichungsform unter verwendung eines planetwalzenextruders |
| EP1765303B2 (de) | 2004-07-01 | 2022-11-23 | Grünenthal GmbH | Gegen missbrauch gesicherte, oral tablette |
| PL1786403T3 (pl) | 2004-07-01 | 2013-10-31 | Gruenenthal Gmbh | Doustna postać dawki zabezpieczona przed nadużywaniem zawierająca (1R, 2R)-3-(3-dimetyloamino-1-etylo0-2-metylo-propylo)fenol |
| JP4563787B2 (ja) * | 2004-12-10 | 2010-10-13 | 日立プラズマディスプレイ株式会社 | プラズマディスプレイ装置及びその制御方法 |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| JP5161075B2 (ja) | 2005-06-03 | 2013-03-13 | エガレット エイ/エス | 分散媒体の第1フラクションとマトリックスの第2フラクションを有し、第2フラクションが胃腸の液体に少なくとも部分的に最初に曝される固形の医薬組成物 |
| US20100172989A1 (en) | 2006-01-21 | 2010-07-08 | Abbott Laboratories | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| US20090022798A1 (en) * | 2007-07-20 | 2009-01-22 | Abbott Gmbh & Co. Kg | Formulations of nonopioid and confined opioid analgesics |
| MX2008009267A (es) * | 2006-01-21 | 2008-10-09 | Abbott Gmbh & Co Kg | Forma farmaceutica y metodo para la administracion de farmacos de abuso. |
| US20090317355A1 (en) * | 2006-01-21 | 2009-12-24 | Abbott Gmbh & Co. Kg, | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| CA2930487A1 (en) | 2007-01-16 | 2008-07-24 | Egalet Ltd. | Use of i) a polyglycol and ii) an active drug substance for the preparation of a pharmaceutical composition for i)mitigating the risk of alcohol induced dose dumping and/or ii) reducing the risk of drug abuse |
| DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
| WO2008132707A1 (en) * | 2007-04-26 | 2008-11-06 | Sigmoid Pharma Limited | Manufacture of multiple minicapsules |
| EP2155167A2 (en) | 2007-06-04 | 2010-02-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
| EP2249811A1 (en) | 2008-01-25 | 2010-11-17 | Grünenthal GmbH | Pharmaceutical dosage form |
| CN107028908A (zh) * | 2008-10-27 | 2017-08-11 | 阿尔扎公司 | 对乙酰氨基酚/曲马多口服延释剂型 |
| US20100203129A1 (en) | 2009-01-26 | 2010-08-12 | Egalet A/S | Controlled release formulations with continuous efficacy |
| WO2010088911A1 (en) | 2009-02-06 | 2010-08-12 | Egalet A/S | Pharmaceutical compositions resistant to abuse |
| CA2766179A1 (en) | 2009-06-24 | 2010-12-29 | Egalet Ltd. | Controlled release formulations |
| PE20121067A1 (es) * | 2009-07-22 | 2012-09-05 | Gruenenthal Chemie | Forma de dosificacion de liberacion controlada extruida por fusion en caliente |
| PT2838512T (pt) * | 2012-04-18 | 2018-11-09 | Gruenenthal Gmbh | Forma farmacêutica resistente à adulteração e resistente à libertação inesperada de alta quantidade (dose-dumping) |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
-
2014
- 2014-12-15 MX MX2016007848A patent/MX2016007848A/es unknown
- 2014-12-15 AU AU2014365038A patent/AU2014365038B2/en not_active Expired - Fee Related
- 2014-12-15 EP EP14811930.8A patent/EP3082781A1/en not_active Withdrawn
- 2014-12-15 CA CA2933983A patent/CA2933983A1/en not_active Abandoned
- 2014-12-15 WO PCT/EP2014/077748 patent/WO2015091352A1/en not_active Ceased
- 2014-12-15 US US14/569,817 patent/US20150164807A1/en not_active Abandoned
- 2014-12-15 JP JP2016540038A patent/JP2016540798A/ja active Pending
-
2016
- 2016-08-05 US US15/229,531 patent/US20160338976A1/en not_active Abandoned
-
2018
- 2018-01-30 US US15/883,271 patent/US20180221307A1/en not_active Abandoned
-
2019
- 2019-06-10 JP JP2019107622A patent/JP2019172688A/ja not_active Withdrawn
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