JP2016536368A5 - - Google Patents
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- Publication number
- JP2016536368A5 JP2016536368A5 JP2016552435A JP2016552435A JP2016536368A5 JP 2016536368 A5 JP2016536368 A5 JP 2016536368A5 JP 2016552435 A JP2016552435 A JP 2016552435A JP 2016552435 A JP2016552435 A JP 2016552435A JP 2016536368 A5 JP2016536368 A5 JP 2016536368A5
- Authority
- JP
- Japan
- Prior art keywords
- factor
- composition
- deficiency
- hemophilia
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361898884P | 2013-11-01 | 2013-11-01 | |
| US61/898,884 | 2013-11-01 | ||
| US201361918341P | 2013-12-19 | 2013-12-19 | |
| US61/918,341 | 2013-12-19 | ||
| PCT/US2014/063676 WO2015066606A2 (en) | 2013-11-01 | 2014-11-03 | Compositions and methods for increasing the half-life of factor xa |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016536368A JP2016536368A (ja) | 2016-11-24 |
| JP2016536368A5 true JP2016536368A5 (https=) | 2017-12-14 |
| JP6629744B2 JP6629744B2 (ja) | 2020-01-15 |
Family
ID=53005403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016552435A Expired - Fee Related JP6629744B2 (ja) | 2013-11-01 | 2014-11-03 | 第Ｘａ因子の半減期を延ばす組成物および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20160235824A1 (https=) |
| EP (1) | EP3063170A4 (https=) |
| JP (1) | JP6629744B2 (https=) |
| CA (1) | CA2928762A1 (https=) |
| WO (1) | WO2015066606A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2950813B1 (en) * | 2013-01-31 | 2019-09-04 | Pfizer Inc | Compositions and methods for counteracting factor xa inhibition |
| MY173548A (en) | 2013-09-24 | 2020-02-04 | Pfizer | Fxa variant compositions |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6262047B1 (en) | 1996-10-11 | 2001-07-17 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6369080B2 (en) | 1996-10-11 | 2002-04-09 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6133256A (en) | 1997-04-14 | 2000-10-17 | Cor Therapeutics Inc | Selective factor Xa inhibitors |
| GB9908838D0 (en) * | 1998-09-11 | 1999-06-16 | Univ London | Fibroblast inhibitor |
| US6905683B2 (en) * | 2000-05-03 | 2005-06-14 | Novo Nordisk Healthcare A/G | Human coagulation factor VII variants |
| MX336958B (es) * | 2005-11-15 | 2016-02-05 | Philadelphia Children Hospital | Metodos y composiciones para modular la hemostasia. |
| EP1867660A1 (en) * | 2006-06-14 | 2007-12-19 | CSL Behring GmbH | Proteolytically cleavable fusion protein comprising a blood coagulation factor |
| KR102069498B1 (ko) * | 2007-09-28 | 2020-01-23 | 포톨라 파마슈티컬스, 인코포레이티드 | 인자 Ｘａ 저해제에 대한 안티도트 및 그것을 사용하는 방법 |
| WO2009061697A1 (en) * | 2007-11-09 | 2009-05-14 | The Board Of Trustees Of The University Of Illinois | Anticoagulant antagonist and hemophilia procoagulant |
| EP2364165B1 (en) * | 2008-11-14 | 2018-01-03 | Portola Pharmaceuticals, Inc. | Antidotes for factor xa inhibitors and methods of using the same in combination with blood coagulating agents |
| PT2453910T (pt) * | 2009-07-15 | 2016-12-07 | Portola Pharm Inc | Formulação de dose unitária de antídoto contra inibidores de fator xa para uso na prevenção de sangramento |
| GB2485590A (en) * | 2010-11-22 | 2012-05-23 | Univ Ruprecht Karis Heidelberg | Method for detecting at least one direct factor Xa inhibitors |
| US20160015793A1 (en) * | 2012-02-16 | 2016-01-21 | Portola Pharmacueticals, Inc. | Modulation of factor xa inhibitor mediated blood loss by partial and transient administration of antidote |
| FR3000895B1 (fr) * | 2013-01-11 | 2017-02-24 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies Sa | Utilisation d'antidotes d'inhibiteurs de la coagulation indiques dans la prevention ou le traitement de pathologies thromboemboliques |
| EP2950813B1 (en) * | 2013-01-31 | 2019-09-04 | Pfizer Inc | Compositions and methods for counteracting factor xa inhibition |
-
2014
- 2014-11-03 JP JP2016552435A patent/JP6629744B2/ja not_active Expired - Fee Related
- 2014-11-03 CA CA2928762A patent/CA2928762A1/en not_active Abandoned
- 2014-11-03 WO PCT/US2014/063676 patent/WO2015066606A2/en not_active Ceased
- 2014-11-03 US US15/031,077 patent/US20160235824A1/en not_active Abandoned
- 2014-11-03 EP EP14857821.4A patent/EP3063170A4/en not_active Withdrawn
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