JP2016534028A - Foamable alcohol composition containing branched foaming surfactant - Google Patents

Abstract

A foamable alcohol composition comprising at least 40% by weight alcohol, based on the total weight of the alcohol composition; a foaming surfactant such as a branched polyether dimethicone surfactant; and optionally There is provided a foamable alcohol composition comprising at least one additional component selected from a foaming power enhancer, a skin feel enhancer, and a moisturizer. Foaming surfactants contain a limited amount of VOCs or no VOCs. [Selection] Figure 3

Description

  This application claims priority from US Provisional Application No. 61 / 894,633, filed Oct. 23, 2014, which is hereby incorporated by reference.

  The present invention relates to a foamable alcohol composition, and more particularly, to a foamable alcohol composition containing a foamable surfactant containing only a limited amount of a volatile organic compound.

  Foamed detergents are popular in part because they are easy to spread on the surface. Consumers seem to like the luxury of foam soap products. For one thing, it is necessary to exert the same detergency as a liquid or gel product with less foam because of the large surface area of the foam. A suitably formulated foam product does not produce the drip and splash experienced with conventional gelled or liquid products due to the high surface tension of the foam. This prevents damage to the floor and walls of the facility where the product dispenser is used. Foam products are easier to produce than gelled products that are often formulated with powdered thickeners that are difficult to handle.

  Alcohol products are popular as skin disinfectants. However, since alcohol is known to have strong antifoaming properties, foamable products based on alcohol compositions have problems. Non-aerosol type alcohol foam can also be used, but the foam quality of these products is variable.

  Some of the current non-aerosol type alcohol foam products, particularly those with an alcohol content of 70% by weight or more, contain large bubbles and foams that collapse into a substantially liquid within about 5-45 seconds. Generate.

  Commercially available non-aerosol type alcohol foams are formulated using foaming surfactants containing volatile organic compounds (labeled “VOCs”). VOCs are organic compounds that have high vapor pressures at normal room temperature conditions. Due to their high vapor pressure, they have a low boiling point, which causes many of the molecules to evaporate or sublimate from the liquid or solid form of the compound and become trapped in the surrounding air. Although VOCs are typically not acutely toxic, some have been the subject of research related to potential long-term health effects.

  Examples of VOCs that have been studied include hexamethylcyclotrisiloxane (D3), octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and dodecamethylcyclohexasiloxane (D6). Contains cyclomethicone. In some studies, cyclomethicone has the effect of organ weight variation, has a negative impact on reproductive health and reproductive function, and may be related to the development of benign uterine tumors in rats. It is shown.

  Thus, there is a need for good quality non-aerosol type alcohol foam products and for foaming surfactants that contain only a limited amount of volatile organic compounds or none at all.

The present invention relates to a foamable alcohol composition comprising at least about 40% by weight of a C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition; and a polyether dimethicone foaming interface A foaming agent comprising a polyether dimethicone foaming surfactant comprising 0 to about 1% by weight volatile organic compound based on the total weight of the foaming surfactant. An alcohol composition is provided.

The present invention is further a method of forming a stabilized alcohol foam, comprising at least about 40% by weight of C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition and 0- Polyether dimethicone foaming surfactant comprising about 1% by weight volatile organic compound is combined to form a foamable alcohol composition; in the mixing chamber, said alcohol composition and air or inert gas To form a mixture; and passing the mixture through a non-aerosol bubble pump to form a foam.

  In any of the above specific examples, the alcohol is selected from the group consisting of methanol, ethanol, propanol, butanol, pentanol, hexanol, isomers thereof, and mixtures thereof.

  In any of the embodiments described above, the foamable surfactant is a branched polyether dimethicone surfactant.

［ここで、基Ｒ^２及びＲ^３は、独立して、メチル基又は式

で表されるポリエーテル部分であり、ａは約３−約２１の整数であり、ｂは約１−約７の整数であり、ｃは約０−約４０の整数であり、ｄは約０−約４０の整数であり、及びｅは約０−約４０の整数であり、ただし、ａ≧３×ｂ及びｃ＋ｄ＋ｅ≧５である（ただし、全てのＲがCH₃であることはない）］で表される。１以上の具体例では、少なくとも１つのＲ^３は上記の式で表されるポリエーテル部分である。 In any of the above specific examples, the foamable surfactant is of the formula

[Wherein the groups R ² and R ³ are independently methyl or

A is an integer from about 3 to about 21, b is an integer from about 1 to about 7, c is an integer from about 0 to about 40, and d is about 0. An integer of about 40 and e is an integer of about 0 to about 40, provided that a ≧ 3 × b and c + d + e ≧ 5 (but not all R are CH ₃ )] It is represented by In one or more embodiments, at least one R ³ is a polyether moiety represented by the above formula.

  In any of the above embodiments, the foamable surfactant is a group consisting of branched PEG-8 dimethicone, branched PEG-10 dimethicone, branched PEG-12 dimethicone, and mixtures thereof. Chosen from.

  In any of the above embodiments, the foaming surfactant is a branched PEG-10 dimethicone.

  In any of the above embodiments, the foamable surfactant comprises no more than about 1% by weight cyclomethicone, based on the total weight of the foamable surfactant.

  In any of the above embodiments, the foamable surfactant comprises no more than about 0.1% by weight D3 based on the total weight of the foamable surfactant.

  In any of the above embodiments, the foamable surfactant comprises no more than about 0.1% by weight D4 based on the total weight of the foamable surfactant.

  In any of the above embodiments, the foamable surfactant comprises no more than about 0.2% by weight D5 based on the total weight of the foamable surfactant.

  In any of the above embodiments, the foamable surfactant comprises about 0.1% or less D6 by weight based on the total weight of the foamable surfactant.

  In any of the above embodiments, the foamable surfactant comprises no more than about 0.8% by weight of VOCs based on the total weight of the foamable surfactant.

  In any of the above embodiments, the foamable surfactant comprises no more than about 0.6% by weight of VOCs based on the total weight of the foamable surfactant.

  In any of the above embodiments, the composition further comprises at least one foam stabilizer.

  In any of the embodiments described above, the foamable surfactant is present in an amount of about 0.002 to about 4% by weight based on the total weight of the alcohol composition.

  In any of the above embodiments, the alcohol is present in an amount of at least about 50% by weight based on the total weight of the alcohol composition.

  In any of the above embodiments, the alcohol is present in an amount of at least about 60% by weight based on the total weight of the alcohol composition.

  In any of the above embodiments, the foam stability at room temperature of the foam is at least about 30 seconds.

In any of the above embodiments, the foam stability at room temperature of the foam is at least about 40% by weight of C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition; and foaming Foam foam formed from a foaming alcohol composition comprising a polyether dimethicone foaming surfactant comprising greater than about 1% by weight volatile organic compound based on the total weight of the surfactant. Greater than stability.

In any of the above embodiments, the initial foam height of the foam at room temperature is at least about 40% by weight C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition; and foaming Foam Initial Formed from a Foamable Alcohol Composition Comprising a Polyether Dimethicone Foaming Surfactant Comprising More than about 1% by Weight of Volatile Organic Compound Based on Total Mass of Surfactant Surfactant Greater than bubble height.

In any of the above embodiments, the foam quality at room temperature is at least about 40% by weight of C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition; Foam foam formed from a foaming alcohol composition comprising a polyether dimethicone foaming surfactant comprising greater than about 1% by weight volatile organic compound based on the total weight of surfactant. Bigger than.

FIG. 6 is a photograph showing a surface sample of a stabilized, foamed composition having a rating of 1 on scale 1-5. FIG. 6 is a photograph showing a surface sample of a stabilized, foamed composition having a rating of 3.5 on scale 1-5. It is a scatter diagram which compares foam quality and the quantity of VOCs in a foamable surfactant.

The foamable alcohol composition according to the present invention comprises at least one alcohol and at least one foamable surfactant. In one or more embodiments, the alcohol is a C _1-6 alcohol, ie, an alcohol containing 1-6 carbon atoms. Such alcohols are called lower alcohols. Typically, these alcohols have antibacterial properties. Examples of lower alcohols include (but are not limited to) methanol, ethanol, propanol, butanol, pentanol, hexanol, isomers and mixtures thereof. In one or more embodiments, the alcohol comprises ethanol, propanol, or butanol, or an isomer or mixture thereof. In one or more embodiments, the alcohol comprises isopropanol. In one or more embodiments, the alcohol comprises ethanol. In one or more embodiments, the bactericidal composition comprises a mixture of ethanol and isopropanol. In one or more embodiments, the bactericidal composition comprises a mixture of isopropanol and n-propanol.

  Generally, the bactericidal composition comprises at least about 10% alcohol by weight based on the total weight of the bactericidal composition. In one embodiment, the bactericidal composition comprises at least about 15% alcohol by weight, based on the total weight of the bactericidal composition, and in another embodiment, the bactericidal composition has at least about 20% alcohol by weight. In other embodiments, the bactericidal composition comprises at least about 25% alcohol by weight, and in yet other embodiments, the bactericidal composition comprises at least about 30% alcohol by weight. In yet other embodiments, the bactericidal composition comprises at least about 40% by weight alcohol. In one embodiment, the bactericidal composition comprises at least about 50% alcohol by weight, based on the total weight of the bactericidal composition, and in another embodiment, the bactericidal composition comprises at least about 60% alcohol by weight. In other embodiments, the germicidal composition comprises at least about 65% alcohol by weight, and in yet other embodiments, the germicidal composition comprises at least about 70% alcohol by weight. In yet other embodiments, the bactericidal composition comprises at least about 78% alcohol by weight. In certain instances, some of the required alcohol will be used, especially depending on the other ingredients and / or their amounts used in the composition. In certain embodiments, the bactericidal composition comprises from about 10 to about 98 weight percent alcohol based on the total weight of the bactericidal composition, and in other embodiments, the bactericidal composition comprises from about 15 to about In still other embodiments, the germicidal composition comprises from about 20 to about 90 weight percent alcohol, and in yet other embodiments, the germicidal composition comprises about 30% alcohol. -About 85% by weight of alcohol. In certain embodiments, the bactericidal composition comprises about 50 to about 98 weight percent alcohol based on the total weight of the bactericidal composition, and in other embodiments, the bactericidal composition comprises about 60 to about In still other embodiments, the germicidal composition comprises from about 65 to about 90 weight percent alcohol, and in yet other embodiments, the germicidal composition comprises about 70% by weight alcohol. -About 85% by weight of alcohol.

  Examples of foaming surfactants useful in foaming alcohol compositions include polyether / polydimethylsiloxane copolymers. Polydimethylsiloxane polymers and copolymers are sometimes referred to as dimethicone, or sometimes referred to as silicone. Thus, polyether / polydimethylsiloxane copolymers are sometimes referred to as polyether dimethicone surfactants. Foaming surfactants are further described in US Patent Application Publication No. 2011/0104079, which is hereby incorporated by reference.

  Polyether dimethicone surfactants are generally characterized by containing a polymer backbone having one or more Si—O—Si bonds in the polymer backbone and a polyether group attached to the backbone. Polyether dimethicones (sometimes referred to as dimethicone copolyols) include polyethylene glycol (PEG) dimethicone copolymers and polypropylene glycol (PPG) dimethicone copolymers, as well as polymers containing both PEG and PPG units. included.

  Examples of polyether dimethicone surfactants include dimethicone undecylenate PEG-7, PEG-10 dimethicone, PEG-8 dimethicone, PEG-12 dimethicone, perfluorononylethylcarboxydecyl PEG10, PEG-20 / PPG-23 dimethicone PEG-11 methyl ether dimethicone, bis-PEG / PPG-20 / 20 dimethicone, silicone quat, PEG-9 dimethicone, PPG-12 dimethicone, fluoroPEG-8 dimethicone, PEG 23 / PPG 6 dimethicone, PEG 20 / PPG 23 dimethicone, PEG 17 dimethicone, PEG 5 / PPG 3 methicone, bis PEG 20 dimethicone, PEG / PPG 20/15 dimethicone copolyol and sulfosuccinate blend, PEG-8 dimethicone / dimer acid blend, PEG-8 dimethicone / Fatty acid blend, PEG-8 dimethicone / Cold pressed vegetable oil / Polyquaternium blend, Random block It includes Rimmer, and mixtures thereof.

  The foamable surfactant can have a predominantly branched or linear structure. Branched structures include a backbone chain and a polymer having one or more pendant groups attached to the backbone chain. Branched structures are sometimes referred to as pendant structures. In one or more embodiments, the branched foamable surfactant comprises a silicone backbone chain having one or more polyether groups that hang down. The branched foamable surfactant may or may not have a polyether group at both ends or one end.

  It will be appreciated that small amounts of linear molecules can be present in predominantly branched surfactants. In one embodiment, up to about 20% by weight of the surfactant molecules can have a linear structure, based on the total weight of the foamable surfactant, and in other embodiments, about 10% of the surfactant molecules. Up to about 5% by weight of the surfactant molecules can have a linear structure, and in other embodiments, the surfactant molecules can have a linear structure. No more than about 1% by weight can have a linear structure, and in other embodiments, no more than about 0.5% by weight of the surfactant molecules can have a linear structure.

［ここで、基Ｒ^２及びＲ^３は、独立して、メチル基又は式

で表されるポリエーテル部分であり、ａは約３−約２１の整数であり、ｂは約１−約７の整数であり、ｃは約０−約４０の整数であり、ｄは約０−約４０の整数であり、及びｅは約０−約４０の整数であり、ただし、ａ≧３×ｂ及びｃ＋ｄ＋ｅ≧５である（ただし、全てのＲがCH₃であることはない）］で表される。１以上の具体例では、少なくとも１つのＲ^３は上記の式で表されるポリエーテル部分である。 In one or more embodiments, the foamable surfactant is of the formula

[Wherein the groups R ² and R ³ are independently methyl or

A is an integer from about 3 to about 21, b is an integer from about 1 to about 7, c is an integer from about 0 to about 40, and d is about 0. An integer of about 40 and e is an integer of about 0 to about 40, provided that a ≧ 3 × b and c + d + e ≧ 5 (but not all R are CH ₃ )] It is represented by In one or more embodiments, at least one R ³ is a polyether moiety represented by the above formula.

  In one or more embodiments, the foamable surfactant is a branched polyether dimethyl corn surfactant that contains little or no VOCs.

The polyether dimethicone surfactant is a commercial product. Commercially available polyether dimethicone surfactants include those in the following table.

  In one or more embodiments, the polyether dimethicone surfactant is selected from the group consisting of PEG-10 dimethicone and PEG-12 dimethicone. In one or more embodiments, the polyether dimethicone surfactant is linear. In one or more embodiments, the polyether dimethicone surfactant is characterized by a branched structure. In one or more embodiments, the polyether dimethicone surfactant is PEG-10 methicone having a predominantly branched structure.

  Branched PEG-10 dimethicone is, for example, trade name Silsurf E1310 from Siltch Industries, trade name ES-5612 from DOW Corning, trade name Gransurf 67 from Grant Industries, and trade name Emulsil from Chemsil Silicones, Inc. Commercially available as S-397.

  The foamable surfactant imparts foaming characteristics to the alcohol composition. Importantly, these polyether dimethicone surfactants vary in their ability to produce good quality alcohol foam from lot to lot when used as supplied by the supplier. There is. In general, it was thought that branched polyether dimethicone surfactants could not be used to produce good quality alcohol foam.

  However, it has been found that impurities in the foaming surfactant do not affect foam quality and / or foam stability. In one or more embodiments, impurities such as volatile organic compounds provide poor foam quality and / or foam stability. Advantageously, the foam quality and foam stability of the foam is improved when the amount of impurities in the foamable surfactant is limited, especially when the VOC content is limited. In one or more embodiments, foam quality and foam stability are consistent from batch to batch. Thus, the amount of volatile organic compounds (VOCs) in the foamable surfactant is advantageously limited.

  For the purposes of this specification, VOCs include compounds that have a relatively high vapor pressure at normal room temperature conditions. In one or more specific examples, VOCs include various organic compounds whose boiling point is 250 ° C. or less as measured at standard atmospheric pressure. In one or more specific examples, VOCs include various organic compounds whose boiling points are in the range of 50-260 ° C. (corresponding to having a saturated vapor pressure of about 100 kPa at 25 ° C.).

  In one or more embodiments, at least VOCs include a by-product of a synthetic reaction for the foaming surfactant. In one or more embodiments, some or all of the VOCs is a decomposition product of the foamable surfactant.

  In one or more embodiments, VOCs include cyclomethicone. Examples of VOCs include hexamethylcyclotrisiloxane (D3), octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and dodecamethylcyclohexasiloxane (D6).

  In one or more embodiments, the amount of VOCs is measured by methods known in the art such as gravimetric analysis. VOCs are also identified and quantified by methods known in the art, such as gas chromatography (GC).

  In one or more embodiments, the foamable surfactant comprises 0 to about 1 weight percent total VOCs based on the total weight of the foamable surfactant. In one embodiment, the foamable surfactant comprises 0.8% by weight or less total VOCs based on the total weight of the foamable surfactant, and in another embodiment, the foamable surfactant is 0 Less than 0.6% by weight, in other embodiments, 0.4% by weight or less total VOCs. In one embodiment, the foamable surfactant comprises 0 to about 0.3 weight percent total VOCs based on the total weight of the foamable surfactant. In other embodiments, the foamable surfactant does not include VOCs.

  In one or more embodiments, the foamable surfactant comprises 0 to about 1 weight percent cyclomethicone, based on the total weight of the foamable surfactant. In one embodiment, the foamable surfactant comprises 0.8% by weight or less of cyclomethicone based on the total weight of the foamable surfactant, and in another embodiment, the foamable surfactant is 0.6 mass% or less, and other specific examples contain 0.4 mass% or less. In one embodiment, the foamable surfactant comprises 0 to about 0.3% by weight of cyclomethicone, based on the total weight of the foamable surfactant. In other embodiments, the foamable surfactant does not include cyclomethicone.

  In one or more embodiments, the foamable surfactant comprises 0 to about 0.1 weight percent D3, based on the total weight of the foamable surfactant. In one embodiment, the foamable surfactant comprises 0.08 wt% or less D3 based on the total weight of the foamable surfactant, and in another embodiment, the foamable surfactant is 0.06 wt% or less. In another specific example, 0.01 mass% or less, and in another specific example, 0.008 mass% or less. In other embodiments, the foamable surfactant does not include D3.

  In one or more embodiments, the foamable surfactant comprises 0 to about 0.1 weight percent D4, based on the total weight of the foamable surfactant. In one embodiment, the foamable surfactant comprises 0.05% or less D4 by weight based on the total weight of the foamable surfactant, and in another embodiment, the foamable surfactant is 0.01% or less. In another specific example, 0.008% by mass or less is included. In other embodiments, the foamable surfactant does not include D4.

  In one or more embodiments, the foamable surfactant comprises 0 to about 0.2 weight percent D5, based on the total weight of the foamable surfactant. In one embodiment, the foamable surfactant comprises 0.15 wt% or less D5 based on the total weight of the foamable surfactant, and in another embodiment, the foamable surfactant is 0.12 wt% or less. In another specific example, the content is 0.11% by mass or less. In other embodiments, the foamable surfactant does not include D5.

  In one or more embodiments, the foamable surfactant comprises 0 to about 0.1 weight percent D6, based on the total weight of the foamable surfactant. In one embodiment, the foamable surfactant comprises 0.05% or less D6 by weight based on the total weight of the foamable surfactant, and in another embodiment, the foamable surfactant is 0.01% or less. In another specific example, 0.008% by mass or less is included. In other embodiments, the foamable surfactant does not include D6.

  The amount of foaming surfactant is not particularly limited as long as an amount effective to cause foaming is present. In certain embodiments, the amount effective to cause foaming can vary depending on the amount of alcohol and other components present. In one or more embodiments, the alcohol composition includes at least about 0.1% by weight of the foaming surfactant based on the total weight of the alcohol composition, and in other embodiments, the alcohol composition has at least about 0%. .2% by weight of a foaming surfactant, and in yet other embodiments, the alcohol composition comprises at least about 0.5% by weight of the foaming surfactant, and in other embodiments, alcohol. The composition comprises at least about 1% by weight of a foamable surfactant.

  In one or more embodiments, the foamable surfactant is present in an amount of about 0.1 to about 4% by weight based on the total weight of the alcohol composition. In one or more embodiments, the foamable surfactant is present in an amount of about 0.2 to about 3 weight percent based on the total weight of the alcohol composition. In one or more embodiments, the foamable surfactant is present in an amount of about 0.25 to about 2.5 weight percent based on the total weight of the alcohol composition. In other embodiments, the foamable surfactant is present in an amount of about 0.5 to about 2 weight percent based on the total weight of the alcohol composition. Larger amounts are also expected to be effective in producing foam. All such masses associated with foaming surfactants are based on effective levels and thus do not include carriers or by-products as included in commercial products unless otherwise specified.

  In one or more embodiments, the foamable surfactant is added directly to the alcohol composition. In other embodiments, the foamable surfactant is added to the alcohol composition as a solution or emulsion. In other words, the foamable surfactant can be premixed with the carrier to form a foamable surfactant solution or emulsion, provided that the carrier adversely affects the foaming properties of the alcohol composition. Do not increase the VOC level beyond an acceptable level. When pre-mixing the foamable surfactant to form a foamable surfactant solution or emulsion, the amount of solution or emulsion added to the alcohol composition should be selected to be within the above range. Will be understood.

  The alcohol composition of the present invention can further comprise a wide range of optional ingredients, provided that the optional ingredients do not adversely affect the foaming properties of the alcohol composition or the foam stability of the foam. CTFA International Cosmetic Ingredient Dictionary and Handbook, 11th edition, 2005 and 2004 CTFA International Buyer's Guide, both of which are incorporated herein by reference, are suitable for use in the compositions of the present invention in the skin care industry. Various commonly used cosmetic and pharmaceutical ingredients are described. The alcohol composition provides a continuous or long-lasting alcohol bactericidal action to modify the feel of the final formulation when rubbed and / or dried, with the aim of enhancing or modifying foam quality and foam properties. Thus, co-surfactants can be included to stabilize other ingredients such as fragrances or sunscreens, and to reduce irritation.

  In certain embodiments, the antimicrobial composition comprises one or more humectants. Examples of humectants include propylene glycol, dipropylene glycol, hexylene glycol, 1,4-dihydroxyhexane, 1,2,6-hexanetriol, 1,2-octanediol, sorbitol, butylene glycol, and methylpropanediol. Such propanediol, dipropylene glycol, triethylene glycol, glycerin (glycerol), polyethylene glycol, ethoxydiglycol, polyethylene sorbitol, and combinations thereof. Other humectants include glycolic acid, glycolate, lactate, lactic acid, sodium pyrrolidonecarboxylate, hyaluronic acid, chitin and the like. In one or more embodiments, the humectant is present in an amount of 0 to about 20% by weight based on the total weight of the antimicrobial composition. In one or more embodiments, the humectant is in an amount of about 0.1 to about 10 wt%, in other embodiments in an amount of about 0.25 to about 8 wt%, based on the total weight of the antimicrobial composition. In other embodiments, it is present in an amount of about 0.4 to about 5 weight percent, and in other embodiments in an amount of about 0.5 to about 2.5 weight percent.

  In these or other embodiments, the antimicrobial composition comprises one or more conditioning or moisturizing esters. Examples of esters include cetyl myristate, cetyl myristoleate, and other cetyl esters, diisopropyl sebacate, and isopropyl myristate. In one embodiment, the ester is present in an amount of 10% or less by weight based on the total weight of the antimicrobial composition. In other embodiments, the ester is present in an amount from about 0.5 to about 5 weight percent, and in other embodiments from about 1 to about 2 weight percent, based on the total weight of the antimicrobial composition.

  In one or more embodiments, the antimicrobial composition includes one or more emulsifiers. Examples of emulsifiers include stellaryl alcohol, sorbitan oleate trideceth-2, poloxamer, and PEG-PPG-20 / 6 dimethicone. In one embodiment, the emulsifier is present in an amount up to about 10% by weight based on the total weight of the antimicrobial composition. In other embodiments, the emulsifier is present in an amount of about 0.1 to about 5 weight percent, and in other embodiments from about 0.5 to about 2 weight percent, based on the total weight of the antimicrobial composition.

  In one or more embodiments, the alcohol composition further comprises one or more of PEG-32, PCA cocoyl alginate (CAE), and tocopheryl acetate.

  In one or more embodiments, PEG-32 is present in an amount of about 0 to about 5 weight percent based on the total weight of the alcohol composition. In one or more embodiments, the amount of PEG-32 is about 0.2 to about 2% by weight based on the total weight of the alcohol composition. In other embodiments, PEG-32 is present in an amount of about 0.3 to about 1.5 weight percent based on the total weight of the alcohol composition.

  In one or more embodiments, tocopheryl acetate is present in an amount of 0 to about 5 weight percent, and in other embodiments from about 0.005 to about 2.5, based on the total weight of the alcohol composition. In one or more embodiments, the tocopheryl acetate is present in an amount from about 0.005 to about 0.5 weight percent, and in other embodiments from about 0.1 to about 0.25 weight percent, based on the total weight of the alcohol composition.

  In one or more embodiments, CAE is present in an amount of about 0 to about 0.5 wt.%, And in other embodiments about 0.05 to about 0.40, based on the total weight of the alcohol composition. In one embodiment, the CAE is present in an amount from 0.05 to about 0.22% by weight, and in another embodiment from about 0.15 to about 0.20% by weight, based on the total weight of the alcohol composition.

In one embodiment, alcohol is the only active antimicrobial component introduced into the composition. Thus, in one or more specific examples, the amount of auxiliary antibacterial component is about 1% by weight or less based on the total mass of the alcohol composition, and the term “auxiliary antibacterial agent” refers to various types other than C _1-6 alcohol. Called antibacterial active agent. In one or more embodiments, the amount of the auxiliary antimicrobial component is about 0.5% or less by weight based on the total weight of the alcohol composition, in other embodiments about 0.2% or less, in other embodiments About 0.1% by mass or less, and in another specific example, about 0.05% by mass or less.

  In other embodiments, the composition includes an auxiliary antimicrobial agent in addition to the alcohol. Examples of auxiliary antibacterial agents are triclosan (also known as 5-chloro-2 (2,4-dichlorophenoxy) phenol and marketed by Ciba-Geigy Corporation under the trade name IRGASAN®); Chloroxylenol (also known as 4-chloro-3,5-xylenol, commercially available from Nipa Laboratories Inc. under the trade name NIPACIDE (registered commercial) MX or PX); hexetidine (5-amino-1,3 -Bis (2-ethylhexyl) -5-methyl-hexahydropyrimidine); chlorohexidine gluconate (CHG) and N, N ″ -bis (4-chlorophenyl) -3,12 Chlorohexidine salts, including salts of -diimino-2,4,11,14-tetraazatetradecandiimidiamide; 2-bromo-2-nitropropane-1,3-diol; Benzalkonium chloride; cetylpyridinium chloride; alkylbenzyldimethylammonium chloride; iodine; phenol derivatives, povidone-iodine containing polyvinylpyrrolidinone-iodine; paraben; dimethylol-5,5-dimethylhydantoin (also known as DMDM hydantoin or gridant) And hydantoin and its derivatives including derivatives of 2,4-imidazolinedione and 2,4-imidazolinedione; phenoxyethanol; 1- (3-chloroallyl) -3,5,6-triaza-1-azoniaadamantane chloride Cis isomers (also known as quaternium-15 and commercially available from Dow Chemical Company under the trade name DOWCIL 2000); diazolidinyl urea; benzethonium chloride; methylbenzethonium chloride; and mixtures thereof (But are not limited to). When used, the supplemental antimicrobial agent is present in an amount of about 0.05-1% by weight, based on the total weight of the alcohol composition. In one or more embodiments, the amount of supplemental antibacterial agent is about 0.1 to about 0.8 weight percent based on the total weight of the alcohol composition, and in other embodiments about 0.2 to about 0.6 weight percent. It is a standard. In one or more embodiments, the composition of the present invention comprises CHG.

  The alcohol composition of the present invention can optionally comprise a broader range of topical active agents, which do not adversely affect the foaming properties of the alcohol composition or the foam stability of the foam. .

  In one or more embodiments, the balance of the alcohol composition is water or other suitable solvent.

  The alcohol composition is prepared by simply mixing the ingredients together. The order of addition is not particularly limited and is easily recognized by those skilled in the art. In one or more embodiments, the resulting mixture is a clear and homogeneous solution.

  In one or more embodiments, the viscosity of the composition is about 100 mPas or less as measured by a Brookfield RV viscometer using an RV and / or LV spindle at 22 ° C. ± 3 ° C. , About 50 mPas or less, and in other embodiments, about 25 mPas.

  Propellants may be used to produce a stable foam, but advantageously no propellant is required. In certain embodiments, the amount of propellant is about 1000 ppm or less based on the total mass of the alcohol composition. In one embodiment, the alcohol composition is substantially free of propellants such as hydrocarbon promoters. Substantially free means that the amount of propellant in the alcohol composition is about 100 ppm or less based on the total mass of the alcohol composition.

  The foamable composition of the present invention is used in various types of dispensers typically used for foam products. Advantageously, the foamable composition is optionally foamed by aerosolizing the composition, but an aerosolized product is not required for foaming. Various dispensers that can mix the foamable alcohol composition with air or an inert gas can be used. Inert gases include gases that do not substantially react with the foamable composition or do not adversely affect it. Examples of inert gases include nitrogen, argon, xenon, krypton, neon, and radon. In one embodiment, the alcohol composition is used in a dispenser that uses a non-aerosol foam pump (combining ambient air or inert gas and alcohol composition in a mixing chamber and passing the mixture through a mesh screen). Other non-aerosol foam pumps are also known and can be used.

  Advantageously, the foam of the present invention is a case where a branched polyether dimethicone surfactant is used as the foaming surfactant, and the amount of VOCs in the foaming surfactant is limited. As far as good, it has foam quality and foam stability. The foamable composition of the present invention provides good foam quality and foam stability even at alcohol levels above 60% by weight. Embodiments of the present invention provide good foam quality and foam stability even at alcohol levels above 70% by weight.

Accordingly, the present invention provides a method for forming non-aerosol alcohol foams with improved foam quality and / or foam stability. The method comprises the step of combining a C _1-6 alcohol, a polyether dimethicone foaming surfactant, and water to form a foamable composition, wherein the foamable composition comprises foaming include C _1-6 alcohols of at least 60 weight%, based on the total weight of the sex of the composition, the amount of VOCs in the foaming surfactant is less than 1 weight%, based on the total weight of foaming surfactant It is characterized by being.

The present invention further provides a method of forming a non-aerosol alcohol foam having improved foam quality and / or foam stability. The method comprises combining a C _1-6 alcohol and a polyether dimethicone foaming surfactant, at least one foaming power enhancer, at least one skin feel enhancing agent, at least one humectant, and water, Forming a foamable composition, the foamable composition comprising at least 60% by weight of C _1-6 alcohol based on the total weight of the foamable composition, wherein the foamable interface The amount of VOCs in the activator is 1% by mass or less based on the total mass of the foamable surfactant. Foam quality and / or foam stability is improved compared to foamable compositions that contain the same ingredients, but the foamable surfactants contain greater than about 1% by weight of VOCs.

The present invention further provides a method of forming a non-aerosol alcohol foam having improved foam quality and / or foam stability. The method comprises combining a C _1-6 alcohol, a foaming surfactant, at least one foaming power enhancer, at least one skin feel enhancing agent, at least one humectant, and water to form a foamable composition. Forming foam, wherein the foamable composition comprises at least 60% by weight of C _1-6 alcohol, based on the total weight of the foamable composition, and the foam quality and / or foam stability. Is characterized by an improvement over foaming compositions that do not contain a foaming power enhancer, a skin feel enhancer, and a humectant. In one or more embodiments, the combination of foaming power enhancer, skin feel enhancer, and humectant surprisingly provides a synergistic improvement in foam quality and / or foam stability.

  In one or more embodiments, foam foam stability is measured as the time it takes for the foamed composition to break into a liquid state. This is called the drainage test method. Foams with good foam stability are advantageous because once the foam breaks into a liquid state, it is more likely to drip from the surface, foam pump and / or associated dispenser member.

  In one or more embodiments, foam foam stability is assessed by the following method. The foamable mixture is passed through a non-aerosol foam pump. Attach a Tygon® (etc.) tube to the end of the pump so that there is no air gap. Prepare the pump by slowly operating several times, during which time the pumped product is discarded. In one or more embodiments, the pump is prepared by operating five times. After preparing the pump, pump one or more test aliquots into a graduated container. In one or more embodiments, the centrifuge tube is an approximately 100 ml oil centrifuge tube. In one or more embodiments, about four test aliquots are pumped into a graduated container. In order to achieve consistent results, it is beneficial to pump aliquots into graduated containers in a uniform manner.

  As the foam breaks and becomes liquid, the liquid level in the graduated container increases, which is clearly visible. In one or more embodiments, the time required for the liquid level to rise to a predetermined point is measured. For example, in one or more embodiments, a 100 ml conical oil centrifuge tube is used, about 6 ml of foamable composition is pumped into the tube, and the time required for the liquid level to rise to 3.5 ml is recorded. . Repeat the test and average the results.

  In one or more embodiments, the foam stability of the foam produced when the foamable composition is passed through a non-aerosol foam pump at room temperature is at least about 20 seconds, and in other embodiments at least about 30. Seconds, in other embodiments at least about 1 minute, in other embodiments at least about 80 seconds, in other embodiments at least about 90 seconds, and in other embodiments at least about 3 minutes. In other words, in one or more embodiments, the alcohol composition maintains its foam shape for at least about 3 minutes and does not break into liquid form. In other embodiments, the foam stability is at least about 5 minutes, and in other embodiments, the foam stability is at least about 15 minutes. In one or more embodiments, the foam stability is at least about the time required for the composition to evaporate.

  In one or more embodiments, foam stability is measured by visual inspection. The average bubble size and the relative ratio of large to small bubbles, foam height and density, and foam dissipation can be observed by visual inspection. In one or more embodiments, foam height is also an indicator of foam quality. In one or more embodiments, a visual rating scale can be established to assess foam quality.

  Referring to the drawings, FIG. 1 is a photograph showing a control sample of a surface with a stabilized, foamed composition that has been rated 1 on a scale of 1-5, immediately after the foam is prepared. It is observed that the foam has a small foam height or no foam height and the foam contains some small bubbles but contains a large amount of large, free bubbles that quickly disappear.

  FIG. 2 is a photograph showing a surface control sample with a stabilized, foamed composition having a rating of 4 on a 1-5 scale, immediately after the foam is prepared. It is observed that the foam has a measurable height, contains small, dense bubbles and disappears relatively slowly. A foam with grade 4 will maintain its shape for at least about 20 seconds and will not lose shape completely for over 60 seconds.

  In one or more embodiments, a panel of experts is used to grade the foam quality. In one or more embodiments, 3-5 committees are used. The committee qualifies through a grading that includes the observation and analysis of baseline foam. In one or more embodiments, the committee is trained by using a standard foam that is predetermined to have a clear foam rating, such as foam rating 1, 3, and 5.

  Advantageously, embodiments of the foamable alcohol composition of the present invention produce foam having a foam rating of at least 3, in other embodiments at least 3.5, and in other embodiments at least 4.

  In one or more embodiments, the foam formed from the composition of the present invention has a higher foam quality rating than the foam formed from the comparative composition (wherein the composition of the present invention and the comparative composition). The amount of VOCs in the foamable surfactant of the composition of the present invention is 1% by weight or less based on the total weight of the foamable surfactant, The amount of VOCs in the foaming surfactant is greater than 1% by weight based on the total weight of the foaming surfactant).

  In one or more embodiments, the foam formed from the composition of the present invention has a higher foam quality rating than the foam formed from the comparative composition (wherein the composition of the present invention and the comparative composition). The difference is that the amount of VOCs in the foamable surfactant of the composition of the present invention is 0.8% by mass or less based on the total mass of the foamable surfactant, The amount of VOCs in the resulting foamable surfactant is greater than 0.8% by weight based on the total weight of the foamable surfactant).

  In one or more embodiments, the foam formed from the composition of the present invention has a higher foam quality rating than the foam formed from the comparative composition (wherein the composition of the present invention and the comparative composition). The difference is that the amount of VOCs in the foamable surfactant of the composition of the present invention is 0.6% by mass or less based on the total mass of the foamable surfactant, and the comparative composition The amount of VOCs in the resulting foaming surfactant is greater than 0.6% by weight based on the total weight of the foaming surfactant).

  In one or more embodiments, the foam bubble height is measured. As mentioned above, the initial foam height is used as an indicator of foam quality. In one or more embodiments, the change in foam height over time is also measured.

  It will be understood that various methods are used to measure the foam height of the foam. In one or more embodiments, the following method is used. A foam pump nozzle is used to generate foam from each composition. In one or more embodiments, the pump is a product of code F2, type F2-11 255/150, commercially available from Albea (formerly Airspray International Inc.). A vial is used to collect the foam from the pump dispenser while measuring the foam height. The exact size and composition of the vial is not limited as long as it is consistent from one test sample to another. In one or more embodiments, the vial is made of glass, is 40 or 80 mm high and has an inner diameter of 25 mm and an outer diameter of 27 mm.

  Rinse the pump with water or ethanol for each sample until the water or ethanol is clear by pumping water or ethanol through the pump. The pump dip tube is then removed from the water and the remaining water is dried by a pump and then placed in the composition to be tested.

  To prepare the pump, the pump is activated three times, and then the pump is activated three or more times to clear the solution through the nozzle, thereby ensuring that the system is ready. Three test aliquots of foam can be collected in collection vials by slowly pumping at a rate of about 1 second for each pump. Place the vial containing the foam on a flat surface, start a timer and measure the foam's approximate height (ignoring the height of the remaining non-foaming composition) with a mm scale A small ruler can be used.

  The time taken to measure the foam height must be consistent and in one or more embodiments is about 5 seconds. This is referred to as the initial bubble height. Various compositions that produce foam that is not stable for at least the time required to measure the foam height are considered unstable and are given a foam height rating of 0 mm. Furthermore, a rating of 0 mm is given when the top of the solution has no foam at any location, such as the center. In one or more embodiments, the foam height is recorded after a predetermined time, such as after 1, 3 and 5 minutes, in order to evaluate the foam stability of the foam.

  In one or more embodiments, the foamable composition of the present invention forms a foam having a measurable initial foam height. In one or more embodiments, the foamable composition of the present invention forms a foam having a measurable foam height after about 1 minute. In one or more embodiments, the foamable composition of the present invention forms a foam having a measurable foam height after about 3 minutes. In one or more embodiments, the foamable composition of the present invention forms a foam having a measurable foam height after about 5 minutes.

  In one or more embodiments, the foam formed from the composition of the present invention has a larger initial foam height than the foam formed from the comparative composition (wherein the composition of the present invention and the comparative composition). The amount of VOCs in the foamable surfactant of the composition of the present invention is 1% by weight or less based on the total weight of the foamable surfactant, The amount of VOCs in the foaming surfactant is greater than 1% by weight based on the total weight of the foaming surfactant).

In order to illustrate the practice of the present invention, the following examples have been prepared and tested. However, the examples should not be considered as limiting the scope of the invention. The claims will serve to identify the invention.
[Example]

Examples were prepared as summarized in Table 2 below.

  The foaming surfactant for each sample is a branched PEG-10 dimethicone surfactant. The concentration of total VOCs in the foaming surfactant was measured and summarized in Table 3 below. The term “qs” means an amount sufficient to bring the total to 100% by weight.

The foamable mixture was passed through an Airspray® foam pump. As described above, the foam was visually inspected by a panel of experts and evaluated for quality against a 1-5 rating scale.

  The data from Table 3 is shown graphically in FIG. 3, where it can be seen that the foam quality decreases as the amount of VOCs in the foamable surfactant increases.

  Various changes and modifications within the scope and spirit of the invention will be apparent to those skilled in the art. The present invention is not limited to the illustrative examples shown here.

Claims (22)

A foaming alcohol composition,
At least about 40% by weight of a C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition; and a polyether dimethicone foaming surfactant, said foaming surfactant A foamable alcohol composition comprising a polyether dimethicone foaming surfactant comprising 0 to about 1% by weight of a volatile organic compound based on the total weight of.   The composition according to claim 1, wherein the alcohol is selected from the group consisting of methanol, ethanol, propanol, butanol, pentanol, hexanol, isomers thereof, and mixtures thereof.   The composition of claim 1 wherein the foamable surfactant is a branched polyether dimethicone surfactant. Foaming surfactant has the formula

Wherein each R ² and R ³ group is independently a methyl group or a formula

A is an integer from about 3 to about 21, b is an integer from about 1 to about 7, c is an integer from about 0 to about 40, and d is about 0. An integer of about 40 and e is an integer of about 0 to about 40, provided that a ≧ 3 × b and c + d + e ≧ 5 (but not all R are CH ₃ )] The composition of Claim 1 which is represented by these.   The foaming surfactant is selected from the group consisting of branched PEG-8 dimethicone, branched PEG-10 dimethicone, branched PEG-12 dimethicone, and mixtures thereof. The composition according to 1.   The composition of claim 1 wherein the foaming surfactant is a branched PEG-10 dimethicone.   The composition of claim 1, wherein the foamable surfactant comprises about 1% by weight or less of cyclomethicone based on the total weight of the foamable surfactant.   The composition of claim 1, wherein the foamable surfactant comprises about 0.1% or less by weight of D3 based on the total weight of the foamable surfactant.   The composition of claim 1, wherein the foamable surfactant comprises about 0.1% or less D4 by weight based on the total weight of the foamable surfactant.   The composition of claim 1, wherein the foamable surfactant comprises about 0.2% or less D5 by weight based on the total weight of the foamable surfactant.   The composition of claim 1, wherein the foamable surfactant comprises about 0.1% or less D6 by weight based on the total weight of the foamable surfactant.   The composition of claim 1, wherein the foamable surfactant comprises no more than about 0.8% by weight of VOCs based on the total weight of the foamable surfactant.   The composition of claim 1, wherein the foamable surfactant comprises no more than about 0.6% by weight of VOCs based on the total weight of the foamable surfactant.   The composition of claim 1, wherein the composition further comprises at least one foam stabilizer.   The composition of claim 1, wherein the foamable surfactant is present in an amount of from about 0.002 to about 4 weight percent based on the total weight of the alcohol composition.   The composition of claim 1, wherein the alcohol is present in an amount of at least about 50% by weight, based on the total weight of the alcohol composition.   The composition of claim 1, wherein the alcohol is present in an amount of at least about 60% by weight, based on the total weight of the alcohol composition. A method of forming a stabilized alcohol foam, the method comprising:
Polyether dimethicone foaming comprising at least about 40% by weight C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition; and 0 to about 1% by weight volatile organic compounds Combining foaming surfactants to form a foamable alcohol composition;
Stabilizing in a mixing chamber comprising mixing the alcohol composition and air or an inert gas to form a mixture; and passing the mixture through a non-aerosol foam pump to form a foam. Of forming a concentrated alcohol foam.   The method of claim 18, wherein the foam has a foam stability at room temperature of at least about 30 seconds. The foam stability of foam at room temperature is a foaming alcohol composition,
At least about 40% by weight of a C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition; and a polyether dimethicone foaming surfactant comprising the foaming surfactant Foam Stability of Foams Formed from Foamable Alcohol Compositions Containing Polyether Dimethicone Foaming Surfactant Comprising More than about 1% by Weight of Volatile Organic Compound Based on Total Weight of Agent 19. The method of claim 18, wherein the method is greater than. The initial foam height of the foam at room temperature is a foaming alcohol composition,
At least about 40% by weight of a C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition; and a polyether dimethicone foaming surfactant comprising the foaming surfactant Foam initial foam height formed from a foamable alcohol composition comprising a polyether dimethicone foaming surfactant comprising greater than about 1% by weight volatile organic compound based on the total weight of the agent 19. The method of claim 18, wherein the method is greater than. The foam quality at room temperature is a foaming alcohol composition,
At least about 40% by weight of a C _1-6 alcohol or a mixture of C _1-6 alcohols based on the total weight of the alcohol composition; and a polyether dimethicone foaming surfactant comprising the foaming surfactant From the foam quality of a foam formed from a foaming alcohol composition comprising a polyether dimethicone foaming surfactant comprising greater than about 1% by weight volatile organic compound based on the total weight of the agent. The method of claim 18, wherein

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