JP2016510990A - 酵母細胞中において活性な細菌性キシロースイソメラーゼ - Google Patents

酵母細胞中において活性な細菌性キシロースイソメラーゼ Download PDF

Info

Publication number
JP2016510990A
JP2016510990A JP2016500948A JP2016500948A JP2016510990A JP 2016510990 A JP2016510990 A JP 2016510990A JP 2016500948 A JP2016500948 A JP 2016500948A JP 2016500948 A JP2016500948 A JP 2016500948A JP 2016510990 A JP2016510990 A JP 2016510990A
Authority
JP
Japan
Prior art keywords
seq
xylose
xylose isomerase
sequence
yeast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016500948A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016510990A5 (https=
Inventor
ジョンチアン・チェン
クリステン・ジェイ・ケリー
リック・ダブリュー・イエ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of JP2016510990A publication Critical patent/JP2016510990A/ja
Publication of JP2016510990A5 publication Critical patent/JP2016510990A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01005—Xylose isomerase (5.3.1.5)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP2016500948A 2013-03-11 2014-03-10 酵母細胞中において活性な細菌性キシロースイソメラーゼ Pending JP2016510990A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/792,321 2013-03-11
US13/792,321 US9187743B2 (en) 2013-03-11 2013-03-11 Bacterial xylose isomerases active in yeast cells
PCT/US2014/022358 WO2014164410A1 (en) 2013-03-11 2014-03-10 Bacterial xylose isomerases active in yeast cells

Publications (2)

Publication Number Publication Date
JP2016510990A true JP2016510990A (ja) 2016-04-14
JP2016510990A5 JP2016510990A5 (https=) 2017-04-13

Family

ID=50483494

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016500948A Pending JP2016510990A (ja) 2013-03-11 2014-03-10 酵母細胞中において活性な細菌性キシロースイソメラーゼ

Country Status (11)

Country Link
US (2) US9187743B2 (https=)
EP (1) EP2970937B1 (https=)
JP (1) JP2016510990A (https=)
CN (1) CN105026560B (https=)
AU (2) AU2014249388A1 (https=)
BR (1) BR112015022021A2 (https=)
CA (1) CA2900465A1 (https=)
HU (1) HUE039208T2 (https=)
MY (1) MY172019A (https=)
WO (1) WO2014164410A1 (https=)
ZA (1) ZA201505714B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
CA2985231A1 (en) 2015-06-04 2016-12-08 Bioamber Inc. Biobased production of functionalized alpha-substituted acrylates and c4-dicarboxylates
BR112018002284A2 (pt) 2015-08-05 2018-12-11 Cargill Inc método de fermentação para produzir um bioproduto, levedura crabtree negativa geneticamente engenheirada e método para reduzir a produção de glicerol por uma levedura engenheirada
CA3004177A1 (en) 2015-11-24 2017-06-01 Cargill, Incorporated Genetically modified yeasts and fermentation processes using genetically modified yeasts
WO2018106656A1 (en) 2016-12-06 2018-06-14 Danisco Us Inc Truncated lpmo enzymes and use thereof
WO2019074828A1 (en) 2017-10-09 2019-04-18 Danisco Us Inc CELLOBIOSE DEHYDROGENASE VARIANTS AND METHODS OF USE
US11591376B2 (en) * 2017-10-11 2023-02-28 Wisconsin Alumni Research Foundation (Warf) Over-expression of AZF1 improves the rate of anaerobic xylose fermentation in engineered yeast strains

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013003219A1 (en) * 2011-06-30 2013-01-03 Codexis, Inc. Pentose fermentation by a recombinant microorganism

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716580B2 (en) 1990-06-11 2004-04-06 Somalogic, Inc. Method for the automated generation of nucleic acid ligands
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
JP4327909B2 (ja) 1996-11-13 2009-09-09 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 組み換え生物による１，３―プロパンジオールの生産方法
WO1999028480A1 (en) 1997-12-02 1999-06-10 E.I. Du Pont De Nemours And Company Method for the production of glycerol by recombinant organisms
BRPI0013315B8 (pt) 1999-08-18 2018-02-27 Du Pont fragmento de ácido nucleico isolado, polipeptídeo, gene quimérico, microorganismo, microorganismo recombinante , e. coli recombinante, linhagem klp23 de e. coli recombinante, linhagem rj8 de e. coli recombinante, vetor pdt29, vetor pkp32 e processos de bioprodução de 1,3-propanodiol
DE60325457D1 (de) 2002-01-23 2009-02-05 Royal Nedalco B V Fermentation von pentosezuckern
ES2543385T3 (es) 2003-05-02 2015-08-18 Cargill, Incorporated Especies de levadura genéticamente modificadas y procesos de fermentación que emplean levaduras genéticamente modificadas
SE0302421D0 (sv) 2003-09-11 2003-09-11 Forskarpatent I Syd Ab Construction of new xylose utilizing Saccharomyces cerevisiae strain
SE0400815D0 (sv) 2004-03-26 2004-03-26 Forskarpatent I Syd Ab Traits in recombinant xylose-growing saccharomyces cerevisiae strains using genome-wide transcription analysis
SE0401303D0 (sv) 2004-05-19 2004-05-19 Forskarpatent I Syd Ab Ethanol productivities of microbial strains in fermentation of dilute-acid hydrolyzates depend on their furan reduction capacities
CA2602084C (en) 2005-03-11 2016-08-09 Forskarpatent I Syd Ab Arabinose- and xylose-fermenting saccharomyces cerevisiae strains
WO2006115455A1 (en) 2005-04-27 2006-11-02 Forskarpatent I Syd Ab Fermentation of glucose and xylose in cellulosic biomass using genetically modified saccharomyces cerevisiae and a simultaneous saccharification and co-fermentation process
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
MX359740B (es) 2005-10-26 2018-10-09 Du Pont Produccion fermentativa de alcoholes de cuatro atomos de carbono.
US8206970B2 (en) 2006-05-02 2012-06-26 Butamax(Tm) Advanced Biofuels Llc Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase
US8828704B2 (en) 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
CN101260394A (zh) * 2008-05-05 2008-09-10 广西科学院 褐色喜热裂孢菌木糖异构酶在酿酒酵母中的活性表达与应用
US8440449B2 (en) 2008-09-30 2013-05-14 The United States Of America, As Represented By The Secretary Of Agriculture Transformed Saccharomyces cerevisiae engineered for xylose utilization
CA2746818A1 (en) 2008-12-24 2010-07-01 C5 Yeast Company B.V. Xylose isomerase genes and their use in fermentation of pentose sugars
US20120184007A1 (en) 2009-07-09 2012-07-19 Stephen Picataggio Engineered microorganisms with enhanced fermentation activity
CN102791858B (zh) 2009-12-22 2014-11-26 株式会社丰田中央研究所 木糖异构酶及其利用
WO2011079388A1 (en) 2009-12-30 2011-07-07 Iogen Energy Corporation Modified yeast strains exhibiting enhanced fermentation of lignocellulosic hydrolysates
WO2011149353A1 (en) 2010-05-27 2011-12-01 C5 Yeast Company B.V. Yeast strains engineered to produce ethanol from acetic acid and glycerol
WO2011153516A2 (en) 2010-06-03 2011-12-08 Mascoma Corporation Yeast expressing saccharolytic enzymes for consolidated bioprocessing using starch and cellulose
US8623623B2 (en) 2010-06-29 2014-01-07 E I Du Pont De Nemours And Company Xylose utilization in recombinant Zymomonas
WO2012009272A2 (en) 2010-07-14 2012-01-19 Codexis, Inc. Pentose fermentation by a recombinant microorganism
EP2626423A1 (en) 2012-02-07 2013-08-14 Clariant Produkte (Deutschland) GmbH Pentose-fermenting microorganism
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
CN121462157A (zh) 2024-08-02 2026-02-03 华为技术有限公司 资源配置方法和资源配置装置

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013003219A1 (en) * 2011-06-30 2013-01-03 Codexis, Inc. Pentose fermentation by a recombinant microorganism

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ACCESSION EFU76426: "xylose isomerase [Lachnoanaerobaculum saburreum DSM 3986]", GENBANK[ONLINE], vol. [retrieved on 2017-12-27], JPN6017050916, 27 December 2010 (2010-12-27), ISSN: 0003872683 *
ACCESSION EGG90672: "xylose isomerase [Lachnospiraceae oral taxon 107 str. F0167]", GENBANK[ONLINE], vol. [retrieved on 2017-12-27], JPN6017050911, 25 April 2011 (2011-04-25), ISSN: 0003872681 *
ACCESSION EHO53553: "xylose isomerase [Lachnospiraceae bacterium oral taxon 082 str. F0431]", GENBANK[ONLINE], vol. ，[retrieved on 2017-12-27], JPN6017050913, 10 January 2012 (2012-01-10), ISSN: 0003872682 *
ACCESSION EJP20197: "xylose isomerase [Lachnoanaerobaculum sp.ICM7]", GENBANK[ONLINE], vol. [retrieved on 2017-12-27], JPN6017050910, 13 August 2012 (2012-08-13), ISSN: 0003872680 *

Also Published As

Publication number Publication date
BR112015022021A2 (pt) 2017-08-29
ZA201505714B (en) 2018-05-30
AU2014249388A1 (en) 2015-08-13
CN105026560A (zh) 2015-11-04
US9187743B2 (en) 2015-11-17
MY172019A (en) 2019-11-12
US20160130590A1 (en) 2016-05-12
HUE039208T2 (hu) 2018-12-28
EP2970937B1 (en) 2018-04-25
WO2014164410A1 (en) 2014-10-09
EP2970937A1 (en) 2016-01-20
US20140256048A1 (en) 2014-09-11
CA2900465A1 (en) 2014-10-09
US9371535B2 (en) 2016-06-21
AU2020201031A1 (en) 2020-03-05
CN105026560B (zh) 2020-09-18

Similar Documents

Publication Publication Date Title
JP6422478B2 (ja) 酵母細胞中において活性な雌ウシの第一胃のキシロースイソメラーゼ
Sibirny Biotechnology of yeasts and filamentous fungi
US9371535B2 (en) Bacterial xylose isomerases active in yeast cells
JP2014522634A (ja) イソブタノール発酵の原料としてのリグノセルロース加水分解物
WO2018172328A1 (en) Improved glycerol free ethanol production
EP3298133A1 (en) Acetate consuming yeast cell
US20140178954A1 (en) Expression of xylose isomerase activity in yeast
Dmytruk et al. Development of the thermotolerant methylotrophic yeast Hansenula polymorpha as efficient ethanol producer
US20250333768A1 (en) Recombinant yeast cell
US20120270290A1 (en) Pentose transporter
US20190112590A1 (en) Arabinose isomerases for yeast
EP4370690A1 (en) Recombinant yeast cell
EP4370688A1 (en) Recombinant yeast cell
US20240401088A1 (en) Recombinant yeast cell
EP4370689A1 (en) Recombinant yeast cell
WO2023079050A1 (en) Recombinant yeast cell

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170306

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170306

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180109

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20180409

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20180911