JP2016501062A - 可変用量設定機構を備える薬剤送達装置 - Google Patents
可変用量設定機構を備える薬剤送達装置 Download PDFInfo
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
- A61M2005/3126—Specific display means related to dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/43—General characteristics of the apparatus making noise when used correctly
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6018—General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6036—General characteristics of the apparatus with identification means characterised by physical shape, e.g. array of activating switches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6045—General characteristics of the apparatus with identification means having complementary physical shapes for indexing or registration purposes
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims (11)
- (a)第1のリザーバユニット(35)と、(b)第2のリザーバユニット(30)と、(c)主要ユニット(10)とを備える薬剤送達システム(1)であって、
(a)第1のリザーバユニット(35)は、
第1の濃度を有する所与の薬剤の第1の製剤と
第1の製剤に対応する第1の機械的識別子と
を含み、
(b)第2のリザーバユニット(30)は、
第2の濃度を有する所与の薬剤の第2の製剤と
第2の製剤に対応する第2の機械的識別子(32)と
を含み、
(c)主要ユニット(10)は、
第1のリザーバユニット及び第2のリザーバユニットの何れかが主要ユニットに対してマウントされることを可能にする、マウント手段(20)と
設定用量サイズに応じて、マウントされたリザーバユニットから薬剤を吐出するための薬剤吐出手段であって、
所与の状態に対して所定のきざみ幅で設定される、所与の薬剤に対する所望の用量サイズを、ユーザが設定することを可能にする回転式用量設定部材を含む、用量設定手段(11,12,14,15,19)を備える、薬剤吐出手段と
を含み、
薬剤吐出手段は、きざみ幅が第1の薬剤体積に対応する用量設定部材の第1の角変位量に対応する、第1の状態を有し、
薬剤吐出手段は、きざみ幅が第2の薬剤体積に対応する用量設定部材の第2の角変位量に対応する、第2の状態を有し、
第1のリザーバユニットがマウントされる場合、薬剤吐出手段は第1の識別子を用いて第1の状態に設定され、第2のリザーバユニットがマウントされる場合、薬剤吐出手段は第2の識別子を用いて第2の状態に設定される、
薬剤送達システム(1)。 - 第1の状態及び第2の状態のきざみ幅は、第1の薬剤濃度及び第2の薬剤濃度に対応し、これにより、所与の数のきざみ幅に対して同量の薬剤が吐出される、請求項1に記載の薬剤送達システム。
- 用量設定手段は、第1の所定のきざみ幅及び第2の所定のきざみ幅で設定可能な、ラチェット機構(13、14、15)を備える、請求項1又は2に記載の薬剤送達システム。
- ラチェット機構は、吐出機構の第1の状態及び第2の状態に対応する、第1の状態及び第2の状態を有する、請求項3に記載の薬剤送達システム。
- ラチェット機構は、
第1のきざみ幅サイズを有する第1のラチェットリング(13)、
第2のきざみ幅サイズを有する第2のラチェットリング(14)、
第1のラチェットリングに面し且つ第1のきざみ幅サイズを有する第1のラチェット部分と、第2のラチェットリングに面し且つ第2のきざみ幅サイズを有する第2のラチェット部分とを有する、連結リング(15)
吐出機構の第1の状態及び第2の状態に対応する、第1の状態及び第2の状態を有する、連結手段(19)
を備え、
連結リング及び第2のラチェットリングは、第1の状態で互いに対して回転をロックされ、これにより、第1のきざみ幅サイズを有するラチェットがもたらされ、
連結リング及び第1のラチェットリングは、第2の状態で互いに対して回転をロックされ、これにより、第2のきざみ幅サイズを有するラチェットがもたらされる、
請求項4に記載の薬剤送達システム。 - 第1の製剤及び第2の製剤の各々に対して、同じ所定のきざみ幅で、薬剤用量を表示するように適合される、ディスプレイ手段を更に備える、請求項1から5のいずれか一項に記載の薬剤送達システム。
- 用量設定部材は、第1の回転可能な目盛及び第2の回転可能な目盛の形態のディスプレイ手段に、動作可能に連結され、第1の目盛は吐出手段が第1の状態にある場合に可視であり、第2の目盛は吐出手段が第2の状態にある場合に可視である、請求項1から6のいずれか一項に記載の薬剤送達システム。
- ディスプレイ手段は、用量設定部材に動作可能に連結された、回転可能なドラム部材を備え、第1の目盛及び第2の目盛はドラム部材上に配置される、請求項7に記載の薬剤送達システム。
- ディスプレイ手段は、
プロセッサ手段、
電子制御式ディスプレイ手段、及び用量設定部材に動作可能に連結される、エンコーダ手段、を備え、
第1のリザーバユニットがマウントされる場合、エンコーダ手段は第1の識別子を用いて第1の状態に設定され、第2のリザーバユニットがマウントされる場合、エンコーダ手段は第2の識別子を用いて第2の状態に設定され、
これにより、設定された薬剤用量が、第1の製剤及び第2の製剤の各々に対して、同じ所定のきざみ幅で表示される、
請求項1から8のいずれか一項に記載の薬剤送達システム。 - 主要ユニットは、用量の設定中に、各きざみ幅に対して、所与の状態に対して、触知性及び/又は可聴性の信号を生成するように適合される、信号生成手段を更に備える、
請求項1から9のいずれか一項に記載の薬剤送達システム。 - 薬剤吐出手段は、手動で作動するばね又は予め付勢されたばねにより手動で駆動される、
請求項1から10のいずれか一項に記載の薬剤送達システム。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12193146 | 2012-11-19 | ||
EP12193146.3 | 2012-11-19 | ||
US201261729757P | 2012-11-26 | 2012-11-26 | |
US61/729,757 | 2012-11-26 | ||
PCT/EP2013/074133 WO2014076289A1 (en) | 2012-11-19 | 2013-11-19 | Drug delivery device with variable dose setting mechanism |
Publications (2)
Publication Number | Publication Date |
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JP2016501062A true JP2016501062A (ja) | 2016-01-18 |
JP6433907B2 JP6433907B2 (ja) | 2018-12-05 |
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JP2015542291A Expired - Fee Related JP6433907B2 (ja) | 2012-11-19 | 2013-11-19 | 可変用量設定機構を備える薬剤送達装置 |
Country Status (5)
Country | Link |
---|---|
US (1) | US9675761B2 (ja) |
EP (1) | EP2919835A1 (ja) |
JP (1) | JP6433907B2 (ja) |
CN (1) | CN104780959B (ja) |
WO (1) | WO2014076289A1 (ja) |
Families Citing this family (15)
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USD752211S1 (en) * | 2012-08-01 | 2016-03-22 | Sanofi-Aventis Deutschland Gmbh | Injection device |
TR201808342T4 (tr) * | 2013-05-07 | 2018-07-23 | Sanofi Aventis Deutschland | Bir enjeksiyon cihazına bağlanmaya yönelik bir tamamlayıcı cihaz. |
USD752738S1 (en) * | 2013-09-20 | 2016-03-29 | Sanofi-Aventis Deutschland Gmbh | Injection device |
USD743538S1 (en) * | 2014-01-17 | 2015-11-17 | Sanofi-Aventis Deutschland Gmbh | Injection device |
US10864327B2 (en) | 2016-01-29 | 2020-12-15 | Companion Medical, Inc. | Automatic medication delivery tracking |
IL272781B2 (en) | 2017-08-21 | 2023-12-01 | Lilly Co Eli | Device for administering medicine with a sensing system |
WO2019040117A1 (en) | 2017-08-21 | 2019-02-28 | Eli Lilly And Company | DOSE DETECTION MODULE FOR DRUG DELIVERY DEVICE |
US11077243B2 (en) | 2017-12-12 | 2021-08-03 | Bigfoot Biomedical, Inc. | Devices, systems, and methods for estimating active medication from injections |
US10987464B2 (en) | 2017-12-12 | 2021-04-27 | Bigfoot Biomedical, Inc. | Pen cap for insulin injection pens and associated methods and systems |
US11464459B2 (en) | 2017-12-12 | 2022-10-11 | Bigfoot Biomedical, Inc. | User interface for diabetes management systems including flash glucose monitor |
EP3724889A2 (en) | 2017-12-12 | 2020-10-21 | Bigfoot Biomedical, Inc. | Therapy assist information and/or tracking device and related methods and systems |
US11083852B2 (en) | 2017-12-12 | 2021-08-10 | Bigfoot Biomedical, Inc. | Insulin injection assistance systems, methods, and devices |
US11116899B2 (en) | 2017-12-12 | 2021-09-14 | Bigfoot Biomedical, Inc. | User interface for diabetes management systems and devices |
US11229749B2 (en) | 2018-09-06 | 2022-01-25 | Verily Life Sciences Llc | Plate capacitor for dosage sensing |
US11948671B2 (en) | 2019-04-11 | 2024-04-02 | Medtronic Minimed, Inc. | Intelligent accessories for medicine dispensing device |
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JP2001170176A (ja) * | 1999-11-01 | 2001-06-26 | Becton Dickinson & Co | 多機能アクチュエータを具えた電子式薬剤送出ペン |
WO2011154480A2 (en) * | 2010-06-11 | 2011-12-15 | Sanofi-Aventis Deutschland Gmbh | A drive assembly for a medication delivery device and medication delivery device |
WO2012022771A2 (en) * | 2010-08-19 | 2012-02-23 | Sanofi-Aventis Deutschland Gmbh | Method and system for determining information related to a drug reservoir using an electronic sensor |
Family Cites Families (3)
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EP2258425B1 (en) | 2001-05-16 | 2013-01-30 | Eli Lilly and Company | Medication injector apparatus |
ES2766253T3 (es) * | 2008-09-18 | 2020-06-12 | Becton Dickinson Co | Inyector médico con émbolo con función de trinquete |
US20130289488A1 (en) * | 2010-12-27 | 2013-10-31 | Sanofi-Aventis Deutschland Gmbh | Dedicated Cartridge and Holder |
-
2013
- 2013-11-19 CN CN201380060419.XA patent/CN104780959B/zh not_active Expired - Fee Related
- 2013-11-19 WO PCT/EP2013/074133 patent/WO2014076289A1/en active Application Filing
- 2013-11-19 JP JP2015542291A patent/JP6433907B2/ja not_active Expired - Fee Related
- 2013-11-19 EP EP13798605.5A patent/EP2919835A1/en not_active Withdrawn
- 2013-11-19 US US14/441,032 patent/US9675761B2/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2001170176A (ja) * | 1999-11-01 | 2001-06-26 | Becton Dickinson & Co | 多機能アクチュエータを具えた電子式薬剤送出ペン |
WO2011154480A2 (en) * | 2010-06-11 | 2011-12-15 | Sanofi-Aventis Deutschland Gmbh | A drive assembly for a medication delivery device and medication delivery device |
WO2012022771A2 (en) * | 2010-08-19 | 2012-02-23 | Sanofi-Aventis Deutschland Gmbh | Method and system for determining information related to a drug reservoir using an electronic sensor |
Also Published As
Publication number | Publication date |
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US9675761B2 (en) | 2017-06-13 |
US20150297835A1 (en) | 2015-10-22 |
CN104780959A (zh) | 2015-07-15 |
JP6433907B2 (ja) | 2018-12-05 |
EP2919835A1 (en) | 2015-09-23 |
WO2014076289A1 (en) | 2014-05-22 |
CN104780959B (zh) | 2017-11-17 |
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