JP2016222274A - Lid material of press-through pack - Google Patents
Lid material of press-through pack Download PDFInfo
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- JP2016222274A JP2016222274A JP2015109438A JP2015109438A JP2016222274A JP 2016222274 A JP2016222274 A JP 2016222274A JP 2015109438 A JP2015109438 A JP 2015109438A JP 2015109438 A JP2015109438 A JP 2015109438A JP 2016222274 A JP2016222274 A JP 2016222274A
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- 239000000463 material Substances 0.000 title claims abstract description 43
- 239000011888 foil Substances 0.000 claims abstract description 29
- 229910052782 aluminium Inorganic materials 0.000 claims abstract description 28
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims abstract description 28
- -1 polyethylene terephthalate Polymers 0.000 claims abstract description 21
- 229920000139 polyethylene terephthalate Polymers 0.000 claims abstract description 20
- 239000005020 polyethylene terephthalate Substances 0.000 claims abstract description 20
- 229920005989 resin Polymers 0.000 claims abstract description 12
- 239000011347 resin Substances 0.000 claims abstract description 12
- 239000012790 adhesive layer Substances 0.000 claims abstract description 9
- 230000000149 penetrating effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 7
- 230000035622 drinking Effects 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 description 11
- 239000010410 layer Substances 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 229920002799 BoPET Polymers 0.000 description 7
- 239000000853 adhesive Substances 0.000 description 7
- 230000001070 adhesive effect Effects 0.000 description 7
- 230000000694 effects Effects 0.000 description 5
- 208000032484 Accidental exposure to product Diseases 0.000 description 2
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000003475 lamination Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920000178 Acrylic resin Polymers 0.000 description 1
- 239000004925 Acrylic resin Substances 0.000 description 1
- 239000004593 Epoxy Substances 0.000 description 1
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 1
- 229920002433 Vinyl chloride-vinyl acetate copolymer Polymers 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000009820 dry lamination Methods 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 229920001225 polyester resin Polymers 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 229920002050 silicone resin Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
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Abstract
Description
本発明は、プレススルーパックの蓋材に関する。 The present invention relates to a lid material for a press-through pack.
医薬品などの錠剤やカプセルなどの包装には、プレススルーパック（以下、ＰＴＰという）と呼ばれる包装形態が採用されている。ＰＴＰは、例えば、樹脂シートを包装容器に成形し、包装容器内に錠剤やカプセルなどの内容物を収納したのち、通常、アルミニウム箔と熱接着層とで構成される蓋材を、包装容器のフランジ部に熱接着層を介して熱接着し、内容物を封緘することにより得られる。 A packaging form called a press-through pack (hereinafter referred to as PTP) is employed for packaging tablets such as pharmaceuticals and capsules. For example, after forming a resin sheet into a packaging container and storing the contents such as tablets and capsules in the packaging container, the PTP is usually made up of a lid made of an aluminum foil and a thermal adhesive layer. It is obtained by heat-bonding the flange part via a heat-bonding layer and sealing the contents.
ＰＴＰからの錠剤などの取り出しは、包装容器の部分に指で圧力をかけると、内容物である薬剤が蓋材を突き破り、容易に取り出せるようになっている。このように、ＰＴＰは開封の容易さから、老人や子供でも簡単に薬剤を取り出すことができるため、病院、薬局などに広く普及してきたが、幼児でも簡単に開封できるため幼児が誤って薬剤を飲み込んでしまう事故が生じ、大きな問題となっている。 When taking out a tablet or the like from the PTP, when a pressure is applied to the portion of the packaging container with a finger, the medicine as the contents breaks through the lid and can be easily taken out. In this way, PTP has been widely used in hospitals and pharmacies because it can be easily opened by elderly people and children because of its ease of opening. A swallowing accident has occurred and has become a major problem.
この問題を解消するためには、蓋材の構成が重要であり、高齢者などには開封できるが、幼児には開け難い、いわゆるチャイルドレジスタンス機能付きのＰＴＰ用蓋材や包装形態が提案されている。 In order to solve this problem, the structure of the lid material is important, and so-called child resistance function PTP lid materials and packaging forms that can be opened by elderly people but difficult for infants have been proposed. Yes.
本発明は、より簡単な構成でチャイルドレジスタンス機能を有するＰＴＰ用蓋材を得るために、アルミニウム箔に積層する樹脂フィルム、積層方法について試験、検討を行った結果としてなされたものであり、その目的は、薬剤などの内容物を取り出す際の開封性の容易さを保持するとともに、幼児の誤飲の問題を解消することができるチャイルドレジスタンス機能を有するプレススルーパックの蓋材を提供することにある。 The present invention was made as a result of testing and studying a resin film laminated on an aluminum foil and a lamination method in order to obtain a PTP lid material having a child resistance function with a simpler configuration. An object of the present invention is to provide a cover material for a press-through pack having a child resistance function that can maintain the ease of opening when taking out contents such as medicines and solve the problem of infant accidental ingestion. .
上記の目的を達成するための請求項１によるプレススルーパックの蓋材は、樹脂フィルム、アルミニウム箔、容器に接着するための熱接着層を備えてなるプレススルーパックの蓋材であって、前記樹脂フィルムがポリエチレンテレフタレートフィルムであり、該フィルム面を先端が直径１．８ｍｍの平坦円形状のポンチにより１０ｍｍ／分の速度で突き刺した場合、蓋材が破断するまでのポンチの移動距離が０．４ｍｍ以上０．８ｍｍ未満であることを特徴とする。
The lid of a press-through pack according to
請求項２によるプレススルーパックの蓋材は、請求項１において、前記ポリエチレンテレフタレートフィルム面を先端が直径１．８ｍｍの平坦円形状のポンチにより１０ｍｍ／分の速度で突き刺した場合、ポンチの貫通に要する最大荷重が５〜６Ｎであることを特徴とする。
The press-through pack cover material according to
請求項３によるプレススルーパックの蓋材は、請求項２において、前記アルミニウム箔の厚さが１５〜２５μｍ、前記ポリエチレンテレフタレートフィルムの厚さが２．５〜４μｍであり、アルミニウム箔の厚さに対するポリエチレンテレフタレートフィルムの厚さの比、（ポリエチレンテレフタレートフィルムの厚さ（μｍ）／アルミニウム箔の厚さ（μｍ））が０．１５〜０．２０であることを特徴とする。
The lid material of the press-through pack according to
本発明によれば、薬剤などの内容物を取り出す際の開封性の容易さを保持するとともに、幼児の誤飲の問題を解消することができるチャイルドレジスタンス機能を有するプレススルーパックの蓋材が提供される。また、本発明による蓋材をそなえたＰＴＰをポケットや袋などに入れて持ち歩いたり、他のＰＴＰと一緒にしても、蓋材が破れたりすることもない。 ADVANTAGE OF THE INVENTION According to this invention, the cover material of the press-through pack which has the child resistance function which can eliminate the problem of the accidental ingestion of an infant while holding the ease of opening at the time of taking out contents, such as a chemical | medical agent, is provided. Is done. Moreover, even if the PTP provided with the lid according to the present invention is carried around in a pocket or a bag, or when it is combined with other PTP, the lid is not torn.
以下、本発明によるプレススルーパックの蓋材について説明すると、本発明によるプレススルーパックの蓋材は、樹脂フィルム、アルミニウム箔、容器に接着するための熱接着層を備えてなる。
（アルミニウム箔）：
アルミニウム箔としては、公知のＰＴＰで使用されているアルミニウム箔、例えば、ＪＩＳ等で規定される１Ｎ３０、１０７０、１１００、８０２１、８０７９材などの硬質材（厚さ：１０〜３０μｍ程度）を適用するのが望ましい。
Hereinafter, the lid of the press-through pack according to the present invention will be described. The lid of the press-through pack according to the present invention includes a resin film, an aluminum foil, and a thermal adhesive layer for bonding to a container.
(Aluminum foil):
As the aluminum foil, a hard material (thickness: about 10 to 30 μm) such as 1N30, 1070, 1100, 8021, and 8079 materials defined by JIS or the like is used as a known PTP. Is desirable.
（樹脂フィルム）：
樹脂フィルムとして、ポリエチレンテレフタレートフィルムが望ましく、アルミニウム箔とポリエチレンテレフタレートフィルムとの積層は、ウレタン系、オレフィン系、ブチルゴム系、アクリル樹脂系、ポリエステル系、エポキシ系、シリコーン樹脂系のドライラミネート接着剤を用いたドライラミネート法によるのが好ましい。接着層の厚さは０．５〜５μｍが好ましい。
(Resin film):
Polyethylene terephthalate film is desirable as the resin film, and lamination of aluminum foil and polyethylene terephthalate film uses urethane, olefin, butyl rubber, acrylic resin, polyester, epoxy, and silicone resin dry laminate adhesives. The dry lamination method is preferable. The thickness of the adhesive layer is preferably 0.5 to 5 μm.
（熱接着層）：
熱接着層は、蓋材を包装容器のフランジ部に接着して包装容器に収納された薬剤などの内容物を封緘するためのもので、公知のＰＴＰで用いられている熱接着剤で構成することができ、ポリプロピレン系接着剤、塩化ビニル系接着剤、塩化ビニル−酢酸ビニル系共重合体系接着剤などが適用される。
(Thermal bonding layer):
The thermal adhesive layer is used to seal the contents such as medicine stored in the packaging container by adhering the lid material to the flange portion of the packaging container, and is composed of a thermal adhesive used in a known PTP. Polypropylene adhesives, vinyl chloride adhesives, vinyl chloride-vinyl acetate copolymer adhesives, and the like are applied.
上記は本発明によるプレススルーパックの蓋材の主要構成であり、具体的には、必要に応じて、印刷層、着色層、バーコード層、接着層、オーバーコート層などを設けることができる。 The above is the main configuration of the cover material of the press-through pack according to the present invention. Specifically, a printing layer, a colored layer, a barcode layer, an adhesive layer, an overcoat layer, and the like can be provided as necessary.
樹脂フィルム、アルミニウム箔、熱接着層を備えてなる本発明によるプレススルーパックの蓋材の特徴は、ポリエチレンテレフタレートフィルム面を先端が直径１．８ｍｍの平坦円形状のポンチにより１０ｍｍ／分の速度でフィルム面と垂直方向に突き刺した場合、蓋材が破断するまでのポンチの移動距離（蓋材がポンチで押されて破断までに撓んだ距離）が０．４ｍｍ以上０．８ｍｍ未満であることを特徴とする。 The feature of the cover material of the press-through pack according to the present invention comprising the resin film, the aluminum foil, and the thermal adhesive layer is that the polyethylene terephthalate film surface is formed at a speed of 10 mm / min by a flat circular punch having a tip of 1.8 mm in diameter. When piercing in the direction perpendicular to the film surface, the distance that the punch moves until the lid breaks (the distance that the lid is bent by the punch when it is bent) is 0.4 mm or more and less than 0.8 mm It is characterized by.
市販の包装容器に錠剤を収納して包装容器のフランジにこの蓋材を熱接着してＰＴＰ包装体を作製し、包装容器の底を圧迫して、錠剤が蓋材を破って取り出せるかどうか評価した結果、蓋材が破断するまでのポンチの移動距離（蓋材がポンチで押されて破断までに撓んだ距離）が０．４ｍｍ未満では、蓋材が破れ易く、チャイルドレジスタンス機能を達成することができ難い。ポンチの移動距離が０．８ｍｍ以上では蓋材が破れ難く、錠剤の取り出しが困難であった。 Evaluate whether tablets can be taken out by storing the tablets in a commercially available packaging container, making the PTP package by thermally bonding this lid material to the flange of the packaging container, and pressing the bottom of the packaging container. As a result, when the movement distance of the punch until the lid material breaks (the distance that the lid material is pushed by the punch and bent until the fracture) is less than 0.4 mm, the lid material is easily broken and the child resistance function is achieved. It is difficult to do. When the movement distance of the punch was 0.8 mm or more, the lid material was difficult to tear and it was difficult to take out the tablet.
上記の特性を備えるためには、前記ポリエチレンテレフタレートフィルム面を先端が直径１．８ｍｍの平坦円形状のポンチにより１０ｍｍ／分の速度で突き刺した場合、ポンチの貫通に要する最大荷重が５〜６Ｎであることが望ましい。下限未満では蓋材が破れ易く、チャイルドレジスタンス機能を達成することができ難い。上限を超えると蓋材が破れ難く、薬剤の取り出しが困難となる。 In order to provide the above characteristics, when the polyethylene terephthalate film surface is pierced at a speed of 10 mm / min by a flat circular punch having a diameter of 1.8 mm, the maximum load required to penetrate the punch is 5 to 6 N. It is desirable to be. If it is less than the lower limit, the lid material is easily broken, and it is difficult to achieve the child resistance function. When the upper limit is exceeded, the lid material is difficult to tear and it becomes difficult to take out the medicine.
また、前記アルミニウム箔の厚さが１５〜２５μｍ、前記ポリエチレンテレフタレートフィルムの厚さが２．５〜４μｍで、アルミニウム箔の厚さに対するポリエチレンテレフタレートフィルムの厚さの比、（ポリエチレンテレフタレートフィルムの厚さ（μｍ）／アルミニウム箔の厚さ（μｍ））が０．１５〜０．２０であることが望ましい。この比が下限未満では蓋材が破れ易く、チャイルドレジスタンス機能を達成することができ難い。上限を超えると蓋材が容易に破れ難く、薬剤の取り出しが困難となる。 The thickness of the aluminum foil is 15 to 25 μm, the thickness of the polyethylene terephthalate film is 2.5 to 4 μm, the ratio of the thickness of the polyethylene terephthalate film to the thickness of the aluminum foil, (the thickness of the polyethylene terephthalate film (Μm) / aluminum foil thickness (μm)) is preferably 0.15 to 0.20. If this ratio is less than the lower limit, the lid member is easily broken, and it is difficult to achieve the child resistance function. When the upper limit is exceeded, the lid material is not easily broken, and it is difficult to take out the medicine.
以下、本発明の実施例を比較例と対比して説明し、その効果を実証する。なお、これらの実施例は、本発明の一実施態様を示すものであり、本発明はこれらに限定されない。 Examples of the present invention will be described below in comparison with comparative examples to demonstrate the effects. In addition, these Examples show one embodiment of this invention, and this invention is not limited to these.
実施例１、比較例１
片面に印刷層を有するアルミニウム箔（１Ｎ３０、硬質箔、厚さ２０μｍ）の印刷層面に、表１に示す厚さを有する市販のポリエチレンテレフタレートフィルムを、ウレタン系のドライラミネート接着剤（乾燥後重量４ｇ／ｍ２）を用いてドライラミネートし、アルミニウム箔の他の片面（非印刷面）にポリプロピレン系の熱接着剤（乾燥後重量４ｇ／ｍ２）を塗布し、乾燥させて表１に示す蓋材Ｎｏ．１〜４を作製した。
Example 1 and Comparative Example 1
A commercially available polyethylene terephthalate film having a thickness shown in Table 1 is applied to a printed layer surface of an aluminum foil (1N30, hard foil, thickness 20 μm) having a printed layer on one side, and a urethane-based dry laminate adhesive (weight 4 g after drying) / M 2 ), a polypropylene thermal adhesive (weight after drying 4 g / m 2 ) is applied to the other surface (non-printing surface) of the aluminum foil, and the lid shown in Table 1 is dried. Material No. 1-4 were produced.
突き刺し試験：得られた蓋材１を、図１に示すように、内径３０ｍｍの穴２Ｈを有する治具２上に置き、その上に内径２５ｍｍの穴３Ｈを有する治具３を、治具２の穴２Ｈおよび治具３の穴３Ｈの中心を一致させるよう載置して蓋材１を押さえ、先端が平坦円形状でその直径が１．８ｍｍのポンチ４により、穴３Ｈの中心部から蓋材１のＰＥＴ面を垂直方向に１０ｍｍ／分の速度で突き刺し、蓋材１が破断するまでのポンチ４の移動距離（蓋材がポンチで押されて破断までに撓んだ距離）、およびポンチ４の貫通に要する最大荷重を測定した。
Piercing test: As shown in FIG. 1, the obtained
開封試験：得られた蓋材を市販のＰＴＰ用容器のフランジに熱接着し、容器内に予め錠剤を収納したＰＴＰ包装体を作製して、作製されたＰＴＰ包装体の包装容器の底を指で圧迫して、錠剤が蓋材を破って取り出せるかどうかを評価した。 Opening test: The obtained lid material is thermally bonded to a flange of a commercially available PTP container, a PTP package body in which tablets are stored in advance in the container is prepared, and the bottom of the prepared PTP package body is pointed to the bottom. The tablet was squeezed to evaluate whether the tablet can be removed by breaking the lid.
表1に示すように、アルミニウム箔に厚さ２μｍのＰＥＴフィルムを積層した蓋材Ｎｏ．１は、アルミニウム箔の厚さに対するＰＥＴフィルムの厚さの比が０．１、蓋材が破断するまでのポンチの移動距離が０．３６ｍｍ、ポンチの貫通に要する最大荷重が４．７Ｎで、開封試験では蓋材が簡単に破れ、本発明の効果を達成することができなかった。また、ＰＥＴフィルムを積層しないアルミニウム箔のみの蓋材Ｎｏ．４も、蓋材が破断するまでのポンチの移動距離が０．２９ｍｍ、ポンチの貫通に要する最大荷重が３．７Ｎで、開封試験では蓋材が簡単に破れ、本発明の効果を達成することができなかった。 As shown in Table 1, a cover material No. 1 in which a PET film having a thickness of 2 μm was laminated on an aluminum foil. 1 is that the ratio of the thickness of the PET film to the thickness of the aluminum foil is 0.1, the movement distance of the punch until the lid breaks is 0.36 mm, and the maximum load required to penetrate the punch is 4.7 N, In the opening test, the lid material was easily broken, and the effects of the present invention could not be achieved. In addition, a cover material No. 1 made only of aluminum foil without laminating a PET film. No. 4, the punch travel distance until the lid breaks is 0.29 mm, the maximum load required to penetrate the punch is 3.7 N, and the lid material can be easily broken in the opening test to achieve the effect of the present invention I could not.
アルミニウム箔に厚さ３．５μｍのＰＥＴフィルムを積層した蓋材Ｎｏ．２は、アルミニウム箔の厚さに対するＰＥＴフィルムの厚さの比が０．１７５、蓋材が破断するまでのポンチの移動距離が０．４２ｍｍ、ポンチの貫通に要する最大荷重が５．３Ｎで、開封試験において指で圧したとき、少し硬いが開封は可能であり、チャイルドレジスタンス機能が確認でき、本発明の効果が達成できるものと認められた。 Cover material No. 1 having a 3.5 μm thick PET film laminated on an aluminum foil. 2, the ratio of the thickness of the PET film to the thickness of the aluminum foil is 0.175, the movement distance of the punch until the lid breaks is 0.42 mm, and the maximum load required to penetrate the punch is 5.3 N. When pressed with a finger in the opening test, it was slightly hard but could be opened, and the child resistance function could be confirmed, and it was recognized that the effects of the present invention could be achieved.
アルミニウム箔に厚さ４．５μｍのＰＥＴフィルムを積層した蓋材Ｎｏ．３は、アルミニウム箔の厚さに対するＰＥＴフィルムの厚さの比が０．２２５、蓋材が破断するまでのポンチの移動距離が０．８８ｍｍ、ポンチの貫通に要する最大荷重が６．３Ｎで、開封試験において指で圧したとき、開封が困難であり、本発明の効果を達成することができなかった。 Cover material No. 1 in which a PET film having a thickness of 4.5 μm was laminated on an aluminum foil. 3, the ratio of the thickness of the PET film to the thickness of the aluminum foil is 0.225, the movement distance of the punch until the lid breaks is 0.88 mm, and the maximum load required to penetrate the punch is 6.3 N. When pressing with a finger in the opening test, opening was difficult, and the effects of the present invention could not be achieved.
１ 蓋材
２ 治具
３ 治具
２Ｈ 穴
３Ｈ 穴
４ ポンチ
1
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015109438A JP6559467B2 (en) | 2015-05-29 | 2015-05-29 | Press-through pack lid |
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| JP6559467B2 JP6559467B2 (en) | 2019-08-14 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019137410A (en) * | 2018-02-06 | 2019-08-22 | 株式会社タケトモ | Lid material for the ptp package of pharmaceutical products |
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| JPS60177897A (en) * | 1984-02-24 | 1985-09-11 | 日本電信電話株式会社 | Piezoelectric type drill |
| JP2002178450A (en) * | 2000-12-11 | 2002-06-26 | Mitsubishi Polyester Film Copp | Lid material for ptp packaging |
| JP2005255173A (en) * | 2004-03-09 | 2005-09-22 | Toyo Seikan Kaisha Ltd | Film-like lid having excellent piercing openability |
| JP2006035646A (en) * | 2004-07-27 | 2006-02-09 | Toyo Seikan Kaisha Ltd | Multilayer film and its manufacturing method |
| JP2008308213A (en) * | 2007-06-18 | 2008-12-25 | Ask:Kk | Press-through package |
| JP2015093727A (en) * | 2013-11-14 | 2015-05-18 | 旭化成ケミカルズ株式会社 | Lid material for press-through pack package and package |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60177897A (en) * | 1984-02-24 | 1985-09-11 | 日本電信電話株式会社 | Piezoelectric type drill |
| JP2002178450A (en) * | 2000-12-11 | 2002-06-26 | Mitsubishi Polyester Film Copp | Lid material for ptp packaging |
| JP2005255173A (en) * | 2004-03-09 | 2005-09-22 | Toyo Seikan Kaisha Ltd | Film-like lid having excellent piercing openability |
| JP2006035646A (en) * | 2004-07-27 | 2006-02-09 | Toyo Seikan Kaisha Ltd | Multilayer film and its manufacturing method |
| JP2008308213A (en) * | 2007-06-18 | 2008-12-25 | Ask:Kk | Press-through package |
| JP2015093727A (en) * | 2013-11-14 | 2015-05-18 | 旭化成ケミカルズ株式会社 | Lid material for press-through pack package and package |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019137410A (en) * | 2018-02-06 | 2019-08-22 | 株式会社タケトモ | Lid material for the ptp package of pharmaceutical products |
| JP7129080B2 (en) | 2018-02-06 | 2022-09-01 | 株式会社タケトモ | Lid material for PTP packaging for pharmaceuticals |
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| JP6559467B2 (en) | 2019-08-14 |
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