JP2016161550A - Colorimetric measuring adapter - Google Patents

Abstract

PROBLEM TO BE SOLVED: To allow more reduction of costs at the time of introduction than introducing a dedicated component measuring device.SOLUTION: A colorimetric measuring adapter attachable and detachable to/from an electronic apparatus, includes: a shielding cover that shields a periphery of a camera and a light source included in the electronic apparatus; and a supporting member that supports a test piece used for colorimetric measurement of a specific component in a sample using the camera and the light source in the shielding cover in a state in which the test piece is spaced away from the camera by a predetermined distance.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a colorimetric adapter.

  There is a colorimetric measurement method in which a color changed by the reaction of a sample with a reagent is measured, and a specific component amount in the sample is measured from the color. As a conventional technique to which the colorimetric measurement method is applied, there is a component measuring apparatus that measures the concentration of a component based on the degree of color development of a reagent that reacts with a component contained in a specimen. For example, the irradiating means irradiates light on the test piece to which the specimen adheres, the detecting means detects reflected light reflected by a plurality of different areas on the test piece, and the component concentration calculating means is used in a plurality of different areas. There is a component measurement device that calculates the concentration of a component contained in a sample based on the intensity of reflected light at an end time after a predetermined time has elapsed from the start time at which the sample has infiltrated and coloration has started (for example, Patent Document 1).

  In addition, a chip mounting portion that detachably mounts a chip having a test part, a light emitting element that irradiates light to the test part of the chip at the time of measurement, a light receiving element that receives reflected light reflected by the test part, There is a photometric unit having a holder for storing and holding a light emitting element and a light receiving element, and there is a component measuring device that measures the amount and / or property of a predetermined component in a specimen by measuring a test site (for example, a patent) Reference 2).

  In addition, as a background art according to the present application, there is a method of performing blood analysis using a portable video camera having an objective lens (for example, Patent Document 3). In this method, the video camera is positioned and operated such that the objective lens is completely at least partially occluded by at least part of the appendage that forms part of the individual. Next, the image signal from the video camera is analyzed to estimate information on the blood flow volume or blood component in the appendage. In this way, the video camera may form part of the mobile phone and the objective lens can be completely blocked with a fingertip. The resulting data can be displayed on the mobile phone in real time.

  Further, as a background art according to the present application, there is a sensor output correction method (for example, Patent Document 4). In this method, an LED for light irradiation, a CMOS area sensor via an imaging lens, and a photodetector are arranged for information on the object to be measured. The PC uses a linearization process that corrects the output from the area sensor when the amount of light is changed to be proportional to the output of the light detector, and when measuring a flat plate with uniform density in the plane as the object to be measured. An uneven light correction process is performed to correct the output of each pixel so that the output of each pixel of the area sensor corrected by the linearization process is uniform in the plane.

International Publication No. 2013/061681 Japanese Patent Laying-Open No. 2005-040267 Special table 2011-530316 gazette International Publication No. 2002/039076

  However, since both Patent Document 1 and Patent Document 2 perform colorimetric measurement using a dedicated component measuring device and cannot be used for other purposes, and are not low cost, However, it was not easy to introduce.

  The present invention has been made in view of the above problems, and an object of the present invention is to provide a colorimetric measuring adapter capable of reducing the cost at the time of introduction rather than introducing a dedicated component measuring device.

  One embodiment of the present invention is detachable from an electronic device, and includes a camera and a light-shielding cover that shields the periphery of the light source, and a ratio of specific components in a sample using the camera and the light source in the light-shielding cover. An adapter for colorimetric measurement comprising a support for supporting a test piece used for color measurement at a predetermined distance from the camera.

  According to one embodiment of the present invention, at least one of light irradiated from a light source of an electronic device and its reflected light within a light shielding cover is transmitted through a test piece, and an image formed by at least one of the transmitted light and its reflected light is captured by a camera. By picking up the image, the color of the test piece can be taken into the portable electronic device, and the specific component amount in the sample can be calculated by the electronic device using the color. As a result, most of the components of the dedicated component measuring apparatus can be covered with electronic equipment. Since electronic devices such as smartphones and personal computers are owned by most individuals, the introduction cost of the colorimetric measurement adapter is lower than when a dedicated component measurement device is introduced.

  In the colorimetric measuring adapter of the present invention, the support can be formed of a transparent member that transmits light from the light source or reflected light of the light from the light source.

  The colorimetric measuring adapter of the present invention may further include a reflective material that reflects light from the light source toward the test piece supported by the support.

  The colorimetric measurement adapter of the present invention may further include a reflective material that reflects the light transmitted through the test piece toward the camera.

  The colorimetric measurement adapter of the present invention may further include a reflective material provided around the camera and reflecting light reaching the camera toward the camera.

  The colorimetric measurement adapter of the present invention may further include an optical filter that converts light from the light source into light having a predetermined wavelength.

  The adapter for colorimetric measurement of the present invention is rotatably supported in the light shielding cover, and a plurality of optical filters for converting light from the light source into light of a predetermined wavelength are attached, and the plurality of optical filters are rotated by the rotation. It may further include a rotating body that inserts any of the filters into the optical path of the light from the light source.

  The adapter for colorimetric measurement of the present invention can be formed such that the rotating body is formed in a disc shape and a part of the periphery of the rotating body is exposed outside the light shielding cover.

  The adapter for colorimetric measurement of the present invention is configured such that a slot for inserting and removing the test piece is formed on the outer surface of the light shielding cover, and the test piece inserted into the slot is supported by the support. be able to.

In the colorimetric measuring adapter of the present invention, the test piece has one end and the other end, and includes a colorimetric measuring reagent disposed between the one end and the other end, and the specific component. A flow path for guiding the sample to the reagent, and the support is at a support position where the other end is exposed to the outside of the light shielding cover when one end of the test piece is inserted into the slot. Can be configured to support.

  The colorimetric measurement adapter of the present invention may further include a close-up lens disposed in front of the camera.

  The colorimetric measurement adapter of the present invention may further include a fixture that maintains the mounting posture of the light shielding cover with respect to the portable electronic device.

  In the colorimetric measuring adapter of the present invention, the fixture may be a cover of the portable electronic device that is connected to the light shielding cover and covers the portable electronic device in a close contact state.

  Another aspect of the present invention includes a colorimetric measurement system including the above-described electronic device and a colorimetric measurement adapter. Further, another aspect of the present invention can include a program executed by a computer of an electronic device to which the colorimetric measurement adapter is attached (attached), or a storage medium storing the program.

  According to the present invention, it is possible to reduce the cost at the time of introduction, rather than introducing a dedicated component measuring device.

FIG. 1A is a front view of the component measurement system, and FIG. 1B is a left side view of the component measurement system. FIG. 2 is a diagram schematically showing a cross section when the component measurement system shown in FIG. 1A is cut along line AA in the drawing. FIG. 3A is a diagram schematically illustrating a configuration example of a support. FIG. 3B is a diagram schematically illustrating another configuration example of the support. FIG. 4 shows a configuration example of the test piece. FIG. 5 shows a configuration example of the test piece. FIG. 6 is a diagram illustrating a configuration example of a smartphone. FIG. 7 is a flowchart illustrating a processing example when the measurement application is executed. FIG. 8 is an explanatory diagram of an optical path of light in the adapter device according to the embodiment. FIG. 9 schematically shows a first modification of the adapter device according to the embodiment. FIG. 10 schematically shows a second modification of the adapter device according to the embodiment. FIG. 11 schematically illustrates Modification 3 of the adapter device according to the embodiment.

  Embodiments of the present invention will be described below with reference to the drawings. The following embodiments are examples only, and the present invention is not limited to the configurations of the following embodiments.

  In the following embodiments, a component measurement system using a mobile phone terminal and a colorimetric measurement adapter that causes the mobile phone terminal to function as a component measurement device will be described. In the embodiment, a component measurement system that measures the concentration of glucose in blood by a colorimetric method as a specific component in a sample (specimen) will be described as an example. However, other components other than glucose in blood may be measured, or a sample (specimen) other than blood may be measured.

FIG. 1 is a diagram illustrating an external configuration of a component measurement system (colorimetric measurement system) according to an embodiment. FIG. 1A is a front view of the component measurement system, and FIG. 1B is a left side view of the component measurement system. FIG. 2 is a diagram schematically showing a cross section when the component measurement system shown in FIG. 1A is cut along line AA in the drawing.

  1A and 1B, the component analysis system includes a smartphone 10 including a camera and a light source, and an adapter device 20 that is detachable from the smartphone 10 and provides a structure as a component measurement device ( Equivalent to a colorimetric adapter). The smartphone 10 is an example of “electronic device”. In addition to a mobile phone terminal (cell phone) such as the smartphone 10, various electronic devices such as a PDA (Personal Digital Assistant) with a camera, a laptop personal computer (PC), and a tablet terminal are used as “electronic devices”. Alternatively, a multi-function portable computer can be used. However, it is not essential that the “electronic device” is portable. That is, the “electronic device” may be a fixed electronic device. The fixed electronic device is a general-purpose computer capable of installing an application program for colorimetric measurement, such as a desktop or tower-type PC or workstation. Each of the camera and the light source included in the electronic device may be a built-in or mounted device in the electronic device or a peripheral device whose operation can be controlled by the electronic device by connection to the electronic device.

  The smartphone 10 is formed in a vertically long flat plate shape, and a display 11 and buttons 12 are provided on the front surface thereof. Further, a camera 13 and an LED (Light Emitting Diode) light 14 (hereinafter simply referred to as “LED 14”), which is a light source for imaging of the camera 13, are provided on the upper part of the back surface of the smartphone 10.

  The adapter device 20 includes a cover 21 of the smartphone 10 and a light shielding cover 22 attached to the back surface of the cover 21. The cover 21 is formed according to the outer shape of the smartphone 10 and covers the back surface, each side surface, and the front edge of the smartphone 10 in a close contact state. The cover 21 functions as a fixture of the adapter device 20 that maintains the posture and arrangement of the light shielding cover 22 connected to the cover 21 and the internal structure of the smartphone 10 accommodated in the light shielding cover 22. In addition, as long as the attitude | position with respect to the smart phone 10 of the light shielding cover 22 can be maintained, the part which coat | covers the lower part of the smart phone 10 of the cover 21 may not be. Further, a fixing tool such as a band can be applied instead of the cover 21.

  The light shielding cover 22 has a box-like appearance, shields the surroundings of the camera 13 and the LED 14, and accommodates the internal structure of the adapter device 20. A slit 23 (shown by a broken line in FIG. 2) is provided on the upper part of the light shielding cover 22, and the peripheral edge of the disc-shaped rotating body 24 that holds the plurality of optical filters 31 is exposed from the slit 23. The peripheral edge exposed from the slit 23 is used as a selector or dial for selecting the optical filter 31 manually.

  A slot 26 for inserting and removing the test piece 25 is formed on the left side surface of the light shielding cover 22. A light shielding member (not shown) made of rubber or the like may be provided around the slit 23 and the slot 26 so that light from the outside into the light shielding cover 22 may be shielded. The cover 21 is colored in an opaque color in order to block light from the outside. The color of the cover 21 is black, for example, but may be a color other than black.

  In FIG. 2, at positions corresponding to the camera 13 and the LED 14 on the back surface of the cover 21, a through hole 27 a that guides light emitted from the LED 14 into the light shielding cover 22 and light from the light shielding cover 22 to the camera 13. A through hole 27b for incidence is formed.

The light shielding cover 22 is opened on the front side with respect to the cover 21, and an internal space is formed. Inside the light shielding cover 22, a shaft 29 that extends in the normal direction from the back surface of the cover 21 and rotatably supports (supports) the rotating body 24, and a test piece 25 inserted from the slot 26 is shielded. The support body 28 supported in the width direction of 22 and the reflecting plate 30 attached to the inner wall of the back surface side of the light shielding cover 22 are included.

  A plurality of optical filters 31 are intermittently attached to the rotating body 24 on the circumference facing the LED 14. In the example of FIG. 2, optical filters 31a and 31b are illustrated. Each optical filter 31 converts the wavelength of light emitted from the LED 14 into a desired wavelength. The number of optical filters 31 can be appropriately selected from one or more according to the wavelength of light used for measurement. One of the plurality of optical filters is inserted into the optical path of the light from the LED 14 by the rotation of the rotating body 24. Thereby, the light from LED14 is converted into the light of a predetermined wavelength.

  As an example, the optical filter 31a converts white light from the LED 14 into red light (wavelength 610 to 750 nm). Red light is used as light having a wavelength suitable for measurement of glucose concentration. On the other hand, the optical filter 31b converts white light from the LED 14 into green light (wavelength 500 to 560 nm). Green light is suitable for measuring the concentration of hemoglobin for obtaining a hematocrit value for correcting the glucose concentration.

  The rotating body 24 is formed with a through hole 32 for guiding light to the camera 13 in a state where the optical filter 31 and the rotating body 24 are aligned in the radial direction. In the example of FIG. 2, the through holes 32a and 32b are illustrated. Further, on the surface of the rotating body 24 facing the cover 21, a light-shielding plate that suppresses diffusion of light emitted from the LED 14 and light incident on the camera 13 around each optical filter 31 and each through-hole 32. 33 is provided. The rotating body 24 is locked by a ratchet mechanism or a spring mechanism (not shown) in a state where the optical filter 31 is positioned in front of the LED 14, and the locked state is maintained unless a force in the rotational direction is applied. May be.

  Instead of the rotating body 24, for example, a slit is provided on the upper surface of the light shielding cover 22, a band-shaped member (slider) into which the optical filter 31 is fitted is inserted, and the optical filter 31 is disposed on the front surface of the LED 14. May be. A plurality of types of optical filters 31 may be fitted in the belt-shaped member in series. In this case, the appropriate optical filter 31 can be disposed on the front surface of the LED 14 by changing the insertion depth of the band-shaped member. The band-shaped member may be formed with an index indicating the insertion depth formed in accordance with the position of each optical filter 31. The optical filter 31 is not an essential component, and the configuration related to the optical filter 31 can be omitted.

  The reflector 30 reflects part of the light emitted from the LED 14 and forms an optical path that is directly incident on the camera 13. A plurality of reflectors 30 may be provided as necessary. The reflector 30 is an example of a reflector.

  The support 28 of the test piece 25 supports the test piece 25 in a state of being separated from the camera 13 by a predetermined distance. The predetermined distance is the focal length of the camera 13, for example. However, it is not always essential to be arranged at the focal length of the camera 13. The support 28 extends in the width direction from the slot 26 into the light shielding cover 22, and is inserted on the optical path from the reflection plate 30. The support 28 is formed of a transparent material (transparent member) such as plastic so as to transmit the light reflected by the reflecting plate 30. A hook-shaped stopper 28 a for stopping the insertion of the test piece 25 is formed at the end of the support 28. However, the stopper 28a is not limited to a bowl shape as long as the shape of the stopper 28a is such that the stopper 28a can be brought into contact with the test piece 25 to stop the insertion.

The support 28 also functions as a guide for guiding the test piece 25 to a predetermined position. FIG. 3A is a diagram schematically showing the configuration of the support 28. As shown in FIG. 3A, the support 28 is formed in a U-shaped cross section provided with barbs 28b and 28c, and when the test piece 25 is inserted through the slot 26, the support 28 is inserted. Enter the direction. Return 28b, 28
By c, the test piece 25 is prevented from falling off. With the above configuration, the support 28 can keep the distance between the camera 13 and the test piece 25 constant. The distance between the camera 13 and the test piece 25 is set so that, for example, the test piece 25 is disposed at the focal length of the camera 13.

  Further, as shown in FIG. 3B, the support 28 includes opposed rails 28A and 28B having a U-shaped cross section, and the longitudinal edges of the test piece 25 are supported by the rails 28A and 28B. You may do it. In this case, since the center part of the front surface and the back surface of the test piece 25 is not supported (exposed) by the support 28, the light from the LED 14 or the reflected light thereof is one of the front surface and the back surface of the test piece 25. Can be directly incident on and transmitted to the other. In this case, the support 28 may not be formed of a transparent member.

  4 and 5 show a configuration example of the test piece 25. FIG. In the example shown in FIG. 4, the test piece 25 includes a strip-shaped test paper 251 having one end and the other end, and strip-shaped transparent sheets 252 and 252 that support the test paper 251 from both sides. The test paper 251 carries a reagent that develops color by reacting with glucose in the blood, for example, by being immersed in the reagent. The reagent includes, for example, an oxidoreductase that reacts with glucose. For example, glucose oxidase (GOD) and glucose dehydrogenase (GDH). As the reagent, any existing reagent used for measuring glucose by a colorimetric method can be applied. Note that only the test paper 251 that is not sandwiched between the transparent sheets 252 and 252 may be inserted, or the test paper 251 that has become wet due to blood suction is pasted on one transparent sheet 252 ( You may make it insert the test paper 251) stuck to the transparent sheet 252 with surface tension.

  In the example of FIG. 5, the test piece 25 includes a reagent portion 255 in a space (capillary) obtained by stacking a strip-shaped substrate 253 having one end and the other end, a U-shaped spacer 254, and a cover 256. Are arranged. The opening 258 of the spacer 254 is used as an inlet (dotted inlet) for sucking blood by capillary action when a capillary is formed by lamination. The capillary constitutes a flow path for guiding a sample (blood) containing a specific component to the reagent. The cover 256 has a through hole 57 that communicates with the inside of the capillary, and the through hole 57 is used as an air hole through which air is released when blood is inhaled. The reagent part 255 is formed by, for example, immobilizing a reagent that reacts with glucose on the substrate 253.

  With the above configuration, the test piece 25 shown in FIG. 5 has one end having a spotting port and the other end on the opposite side. When the test piece 25 is inserted into the slot 26, the other end portion is inserted at the head, and when the other end portion comes into contact with the stopper 28a, the spot of one end portion is exposed to the outside of the light shielding cover 22. Put into a state. Thus, when blood is brought into contact with the spotting port, blood is drawn into the capillary by capillary action, and the reagent in the reagent unit 255 is dissolved. In this way, blood can be spotted with the test piece 25 inserted.

FIG. 6 is a diagram illustrating a configuration example of the smartphone 10. In FIG. 6, the smartphone 10 includes a CPU (Central Processing Unit) 41 connected to each other via a bus B,
The memory 42, the RF / BB circuit 43, the antenna 44, the input device 45, the display 11, the camera 13, the LED 14, and the sensor 46 are included. The CPU 41 corresponds to a “processor”, and the memory 42 corresponds to a “storage device” or a “computer-readable storage medium”.

The memory 42 includes a volatile storage medium and a nonvolatile storage medium. The volatile storage medium includes a RAM (Random Access Memory) used as a main storage device. The RAM is used as a work area for the CPU 41, a program development area, and a data storage area. The nonvolatile storage medium includes a ROM (Read Only Memory). The ROM stores an OS (Operating System) and various application programs. Further, the nonvolatile storage medium may include an auxiliary storage device such as a hard disk drive (HDD), flash memory, or EEPROM (Electrically Erasable Programmable Read-Only Memory). The auxiliary storage device is used as a storage area for programs and data.

The RF / BB circuit 43 converts data (digital signal) supplied from the CPU 41 into a baseband (BB) signal, further converts it into an analog wireless (RF (Radio Frequency)) signal, and radiates it from the antenna 44. The RF / BB circuit 43 converts a radio signal received from the antenna 44 into a baseband signal, further converts it into a digital signal (data), and supplies it to the CPU 41.

  The input device 45 is used for inputting information. The input device 45 includes a touch panel in addition to the buttons 12 illustrated in FIG. The display 11 displays various information including the execution result of the program.

  The camera 13 takes an image or a moving image. Image data and moving image data obtained by imaging are stored in the memory 42. The LED 14 is used for irradiating photographing light of the camera 13. The sensor 46 is a temperature sensor, for example. Although not shown, the smartphone 10 includes a microphone and a speaker for making a call.

  The CPU 41 loads the program stored in the memory 42 to the development area and executes it. As a result, the CPU 41 performs various processes. As one of the application programs, an application program (referred to as a measurement application) for performing component measurement using the test piece 25 is installed in the memory 42.

  FIG. 7 is a flowchart illustrating a processing example when the measurement application is executed. In the first step of S1, the user operates the input device 45 to start the measurement application. However, the adapter device 20 includes an audio plug, and when the audio plug is inserted into a jack provided in the smartphone 10, the CPU 41 detects the voltage indicating the insertion of the audio plug of the adapter device 20 and starts executing the measurement application. It may be said.

  Alternatively, the adapter device 20 includes an infrared transmitter or a transmitter for short-range wireless communication (such as Bluetooth (registered trademark)), and the smartphone 10 includes an infrared receiver or a receiver for short-range wireless communication provided in the smartphone 10. For example, the CPU 41 may receive the measurement application activation signal transmitted from the transmitter, and the CPU 41 may activate the measurement application. At the time of measurement, for example, the smartphone 10 is placed on a flat place with the back surface of the light shielding cover 22 facing down and the front surface of the smartphone 10 facing up.

  In the present embodiment, the light shielding cover 22 is formed so as to cover the upper half of the back surface of the smartphone 10. On the other hand, the light shielding cover 22 may be formed so as to cover the entire back surface of the smartphone 10. In this way, when the back surface of the light shielding cover 22 is placed on a flat place, the light shielding cover 22 is in a state of supporting the entire smartphone 10 from the back surface, which is preferable in that stability can be increased.

  In the next step S <b> 2, the CPU 41 displays on the display 11 a screen that prompts the user to insert an unused test piece 25 (sensor) into the slot 26. In addition, the CPU 41 activates the camera 13 and turns on the LED 14 so that the display 11 displays a state in which the test piece 25 is inserted.

In the next step S3, the CPU 41 performs calibration. For example, optical calibration is performed by photographing a blank. The CPU 41 determines that an error has occurred when the value of the blank color obtained by imaging is equal to or greater than a predetermined threshold. The threshold value is set so that, for example, the color of the used test piece 25 is determined as a color equal to or greater than the threshold value.

  In the next step S4, the CPU 41 controls the sensor 46 to measure the ambient temperature. Alternatively, the adapter device 20 may have a temperature sensor, and the temperature in the light shielding cover 22 measured by the temperature sensor may be transmitted to the smartphone 10 by the above-described audio plug or near field communication.

  In the next step S <b> 5, the CPU 41 waits for spotting of blood (sample attachment) as a sample. For example, when the test piece 25 has the configuration shown in FIG. 4, the test piece 25 is once pulled out of the slot 26, the blood is sucked into the test paper 251, and then the test piece 25 is inserted again. The CPU 41 can display an instruction for prompting such work on the display 11.

  Alternatively, when the test piece 25 has the configuration shown in FIG. 5, the blood is brought into contact with the spotting port and introduced into the capillary with the test piece 25 still inserted. In this case, the CPU 41 can cause the display 11 to display an instruction for prompting spotting.

  The CPU 41 monitors the image picked up by the camera 13, and the color value at a predetermined position in the image is changed by inserting the test piece 25 including the test paper 251 that sucked blood or introducing blood into the capillary. If the blood exceeds a predetermined threshold (different from the threshold used in S3), it is determined that the spotting has been completed (step S6).

  When detecting the completion of the spotting, the CPU 41 starts measuring the glucose concentration. Light emitted from the LED 14 when the LED 14 is turned on is reflected by the reflecting plate 30, passes through the support 28 and the test piece 25 supported by the support 28, and reaches the camera 13. An optical path of light is schematically shown in FIG. The arrow in the figure indicates the optical path. The camera 13 captures an image (image) of the test piece 25 formed by the light transmitted through the test piece 25. The image may be an image formed by reflected light of the transmitted light from the test piece 25.

  As described above, the reagent provided in the test piece 25 is dissolved by blood and reacts with the blood to change its color (develop color). The CPU 41 can measure the glucose concentration by measuring the color development degree (coloration) of the test piece 25 in the image captured by the camera 13.

  The CPU 41 performs a calculation for converting the color measurement result of coloration, that is, the value of coloration into a glucose concentration, and displays the calculation result, that is, the glucose concentration on the display 11 (step S7).

  In this way, the adapter device 20 can perform colorimetric measurement of the glucose concentration using the smartphone 10. In the above processing, the glucose concentration is obtained from the coloration in the image. However, using the test piece 25 having the configuration shown in FIG. It is also possible to take a video of the changing state with the camera 13 and measure a specific component of the sample from the state of the change.

  FIG. 9 schematically illustrates a first modification of the adapter device 20 according to the embodiment. In FIG. 9, the cover 21, the light shielding cover 22, the rotating body 24, and the support body 28 are not shown. In the first modification, the test piece 25 is disposed immediately below the LED 14. In this case, the light transmitted through the test piece 25 is reflected by the reflecting plate 30 and enters the camera 13. Even in this case, a suitable component measurement can be performed.

  FIG. 10 schematically shows a second modification of the adapter device 20 according to the embodiment. In FIG. 10, the cover 21, the light shielding cover 22, the rotating body 24, and the support body 28 are not shown. In the second modification, a reflecting plate 30A having a substantially mountain-shaped cross section surrounding the camera 13 is provided. The reflection plate 30 </ b> A reflects the light reaching the periphery of the camera 13 toward the camera 13. Thereby, the condensing degree of the light to the camera 13 can be improved. The reflection plate 30A is attached to the back surface of the cover 21, for example. Or it is supported by the support part which is not shown in figure. The reflector 30A is an example of a reflector.

  FIG. 11 schematically shows a third modification of the adapter device 20 according to the embodiment. In FIG. 11, the cover 21, the light shielding cover 22, the rotating body 24, and the support body 28 are not shown. In Modification 3, a close-up lens 40 is disposed in front of the camera 13, that is, between the camera 13 and the test piece 25. The close-up lens 40 is provided when the test piece 25 cannot be disposed at the focal length of the camera 13. The close-up lens 40 is attached to the back surface of the cover 21, for example. Or it is supported by the support part which is not shown in figure. By providing the close-up lens 40, an image focused by the camera 13 can be obtained.

  The embodiment can be further modified as follows. For example, in the embodiment, as shown in FIGS. 1A and 1B, a part of the rotating body 24 is exposed to the outside of the light shielding cover 22, and the rotating body 24 is rotated manually by a finger or the like. I'm trying to do it. Instead of this configuration, a configuration in which the entire rotating body 24 is accommodated in the light shielding cover 22 and the rotation (selection of the optical filter 31) is controlled by a push button exposed from the upper surface or side surface of the light shielding cover 22 may be adopted. good.

  For example, the push button has one end and the other end, is formed in a rod shape that reciprocates by, for example, a spring mechanism, and one end is exposed outside the light shielding cover 22 and used as a push button. The other end is connected to a crank mechanism (not shown), and the crank mechanism is connected to the shaft 29. When the push button is pressed, one end of the push button sinks, and when the pressing force is released, the spring button returns to the original position. The reciprocating motion of the push button at this time is converted into the rotational motion of the shaft 29 by the crank mechanism, and the rotating body 24 attached to the shaft 29 is rotated by a predetermined angle. The predetermined angle is set to an angle at which the optical filter 31 facing the LED 14 is replaced. As described above, a part of the rotating body 24 may be exposed outside the light shielding cover 22, or the entire rotating body 24 may be accommodated in the light shielding cover 22.

  In the embodiment, the test piece 25 is configured to be attached to the light shielding cover 22 one by one. Instead, a configuration in which a cartridge (not shown) that accommodates a plurality of test pieces 25 is accommodated in the light shielding cover 22 or integrally connected to the light shielding cover 22 may be employed. For example, a configuration in which a plurality of test pieces 25 are accommodated in a cartridge in a stacked state, and one of the test pieces 25 is discharged from the cartridge by a predetermined operation on the cartridge and supported by the support body 28 (first). 1 configuration).

  Alternatively, a configuration in which a plurality of test pieces 25 are bonded in series on a tape-shaped film and the film is housed in a cartridge in a wound state may be employed. In this case, the film in a wound state is pulled out by a predetermined operation on the cartridge, and one test piece 25 on the film is peeled off from the film and supported by the support 28 (second configuration). In both the first and second configurations, a part of the test piece 25 supported by the support 28 is exposed to the outside of the light-shielding cover 22, and the specimen (blood) is pressed against the exposed portion so that it can be spotted. Preferably it is done.

According to the adapter device 20 of the embodiment, colorimetric measurement can be performed using the camera 13 of the smartphone 10. This eliminates the need for a dedicated measuring instrument. In addition, by linking with the smartphone 10, the measurement result can be transmitted to other communication devices by wireless communication, or information related to component measurement can be received from other communication devices.

  In addition, by installing various application programs such as an application for managing the user's lifestyle based on component measurement and a high-accuracy management application for the colorimetric measurement system, a variety of measurement results can be used. Function can be obtained.

  Moreover, since it becomes possible to produce | generate the light of various wavelengths using the optical filter 31, the white light irradiated from LED14 can measure many items.

  In the colorimetric measurement using the adapter device 20, information processing related to the measurement is performed using the smartphone 10 in addition to the camera 13 and the LED 14. Since the smartphone 10 is often owned by an individual, only the adapter device 20 needs to be purchased for introduction. For this reason, the adapter device 20 can be provided at a lower price than a dedicated component measuring device. As a result, the cost associated with the introduction of the colorimetric measurement system can be reduced. The configurations described in the above embodiments can be combined as appropriate.

10 ... Smartphone 13 ... Camera 14 ... Light source (LED)
20 ... Adapter device 21 ... Cover 22 ... Shading cover 23, 26 ... Slit 24 ... Rotating body 25 ... Test piece 27a, 27b ... Through hole 28 ... Support 29 ... Shaft 30 ... Reflector (reflector)
31 ... Optical filter

Claims (15)

An adapter for colorimetric measurement that is detachable from an electronic device,
A light shielding cover that shields the surroundings of the camera and the light source provided in the electronic device;
A support for supporting a test piece used for colorimetric measurement of a specific component using the camera and a light source in a light shielding cover in a state of being separated from the camera by a predetermined distance;
Adapter for colorimetric measurement including. The colorimetric measurement adapter according to claim 1, wherein the support is formed of a transparent member that transmits light from the light source or reflected light of the light from the light source. The adapter for colorimetric measurement according to claim 1 or 2, further comprising a reflective material that reflects light from the light source toward a test piece supported by the support. The colorimetric measurement adapter according to any one of claims 1 to 3, further comprising a reflective material that reflects light transmitted through the test piece toward the camera. The colorimetric measurement adapter according to any one of claims 1 to 4, further comprising a reflective material provided around the camera and reflecting light reaching the camera toward the camera. The colorimetric measurement adapter according to any one of claims 1 to 5, further comprising an optical filter that converts light from the light source into light having a predetermined wavelength. A plurality of optical filters which are rotatably supported in the light shielding cover and convert light from the light source into light of a predetermined wavelength are attached, and any one of the plurality of optical filters is rotated by the rotation from the light from the light source. The adapter for colorimetric measurement according to any one of claims 1 to 5, further comprising a rotating body to be inserted into the optical path. The colorimetric measurement adapter according to claim 7, wherein the rotating body is formed in a disk shape, and a part of a peripheral edge thereof is exposed outside the light shielding cover. A slot for inserting and removing the test piece is formed on the outer surface of the light shielding cover,
The adapter for colorimetric measurement according to claim 1, wherein the test piece inserted into the slot is supported by the support. The test piece has one end and the other end, a colorimetric reagent disposed between the one end and the other end, and a flow path for guiding the sample containing the specific component to the reagent Including
The colorimetric measurement adapter according to claim 9, wherein the support supports the test piece at a support position where the other end is exposed to the outside of the light shielding cover when one end of the test piece is inserted into the slot. . The colorimetric measurement adapter according to any one of claims 1 to 10, further comprising a close-up lens arranged in front of the camera. The colorimetric measurement adapter according to any one of claims 1 to 11, further comprising a fixture that maintains a mounting posture of the light shielding cover with respect to the electronic device. The colorimetric measurement adapter according to claim 12, wherein the fixture is a cover of the electronic device that is connected to the light shielding cover and covers the electronic device in a close contact state. An electronic device including a camera, a light source, a storage device storing a program, and a processor for executing the program;
A light-shielding cover that shields light from the camera and the light source, and supports a test piece used for colorimetric measurement of a specific component using the camera and the light source in the light-shielding cover with a predetermined distance from the camera. A colorimetric adapter that is detachably attached to the electronic device,
With
The processor is configured such that, by executing the program, at least one of a process of irradiating light from the light source, light from the light source and reflected light of light from the light source is supported by the support, and the specimen is attached. Based on the process of taking an image of the test piece formed by at least one of the transmitted light and the reflected light when transmitted through the test piece, and the color of the image of the test piece taken by the camera A colorimetric measurement system that performs processing for measuring the specific component in a specimen. A camera and a light shielding cover that shields the surroundings of the light source and the camera included in the electronic device, and a test piece used for the colorimetric measurement of a specific component using the camera and the light source in the light shielding cover with a predetermined distance from the camera In the computer of the electronic device to which a colorimetric adapter including a support that supports the electronic device is attached,
Irradiating light from the light source;
At least one of the light from the light source and the reflected light of the light from the light source is formed by at least one of the transmitted light and the reflected light that is supported by the support and passes through the test piece to which the specimen is attached. Capturing an image of the test piece with the camera;
A program for executing the step of measuring the specific component in the specimen based on the color of the image of the test piece imaged by the camera.