JP2015530087A5 - - Google Patents

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Publication number
JP2015530087A5
JP2015530087A5 JP2015529031A JP2015529031A JP2015530087A5 JP 2015530087 A5 JP2015530087 A5 JP 2015530087A5 JP 2015529031 A JP2015529031 A JP 2015529031A JP 2015529031 A JP2015529031 A JP 2015529031A JP 2015530087 A5 JP2015530087 A5 JP 2015530087A5
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JP
Japan
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species
human
immune library
target antigen
antibody molecule
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JP2015529031A
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English (en)
Japanese (ja)
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JP2015530087A (ja
JP6391574B2 (ja
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Priority claimed from PCT/EP2013/067979 external-priority patent/WO2014033252A1/en
Publication of JP2015530087A publication Critical patent/JP2015530087A/ja
Publication of JP2015530087A5 publication Critical patent/JP2015530087A5/ja
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Publication of JP6391574B2 publication Critical patent/JP6391574B2/ja
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JP2015529031A 2012-08-31 2013-08-30 種間標的内交差反応性を有する抗体分子を産生する方法 Active JP6391574B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261695664P 2012-08-31 2012-08-31
US61/695,664 2012-08-31
PCT/EP2013/067979 WO2014033252A1 (en) 2012-08-31 2013-08-30 Method for producing antibody molecules having inter-species, intra-target cross-reactivity

Publications (3)

Publication Number Publication Date
JP2015530087A JP2015530087A (ja) 2015-10-15
JP2015530087A5 true JP2015530087A5 (https=) 2017-09-21
JP6391574B2 JP6391574B2 (ja) 2018-09-26

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JP2015529031A Active JP6391574B2 (ja) 2012-08-31 2013-08-30 種間標的内交差反応性を有する抗体分子を産生する方法

Country Status (10)

Country Link
US (1) US20150203840A1 (https=)
EP (2) EP2977386A1 (https=)
JP (1) JP6391574B2 (https=)
CN (1) CN104583238A (https=)
AU (2) AU2013310924B2 (https=)
CA (1) CA2878712A1 (https=)
DK (1) DK2890711T3 (https=)
IL (1) IL236523B (https=)
IN (1) IN2015DN00140A (https=)
WO (1) WO2014033252A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2686347B1 (en) 2011-03-16 2018-05-02 argenx BVBA Antibodies to cd70
ES2860952T3 (es) 2013-08-01 2021-10-05 Univ Catholique Louvain Proteína anti-garp y usos de la misma
US10391168B1 (en) 2014-08-22 2019-08-27 University Of Bern Anti-CD70 combination therapy
WO2018007999A1 (en) 2016-07-08 2018-01-11 Staten Biotechnology B.V. Anti-apoc3 antibodies and methods of use thereof
GB201612337D0 (en) 2016-07-15 2016-08-31 Argen-X N V Ant-il-22r antibodies
CN110506056A (zh) 2017-04-21 2019-11-26 斯塔滕生物技术有限公司 抗apoc3抗体和其使用方法
GB201707561D0 (en) 2017-05-11 2017-06-28 Argenx Bvba GARP-TGF-beta antibodies
PE20210119A1 (es) 2017-10-31 2021-01-19 Staten Biotechnology B V Anticuerpos anti-apoc3 y metodos de uso de estos
AU2018383709B2 (en) 2017-12-12 2025-09-11 Pionyr Immunotherapeutics, Inc. Anti-TREM2 antibodies and related methods
GB201800649D0 (en) 2018-01-16 2018-02-28 Argenx Bvba CD70 Combination Therapy
WO2019151865A1 (en) 2018-02-05 2019-08-08 Stichting Vu Inverse agonistic anti-us28 antibodies
WO2020080941A1 (en) 2018-10-16 2020-04-23 Umc Utrecht Holding B.V. Anti- low-density lipoprotein receptor-related protein 5/6 antibodies
JP7789368B2 (ja) * 2020-05-29 2025-12-22 学校法人 久留米大学 炎症性腸疾患に対する治療用抗体
EP4277706A1 (en) 2021-01-15 2023-11-22 Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis Inducers of senescence, in combination with a selective death receptor 5 (dr5) agonist, for use in a method of treating cancer
WO2024096735A1 (en) 2022-10-31 2024-05-10 Stichting Amsterdam UMC Single domain anti-cd169 antibodies
WO2024101989A1 (en) 2022-11-08 2024-05-16 Stichting Amsterdam UMC Activation inducible antigen receptors for adoptive immunotherapy
EP4631501A1 (en) 2024-04-09 2025-10-15 Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis Combinations of a calcium homeostasis disruptor with a death receptor 5 agonist for treating cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1034298T3 (da) * 1997-12-05 2012-01-30 Scripps Research Inst Humanisering af murint antistof
CN1735629B (zh) * 2002-11-08 2012-05-09 埃博灵克斯股份有限公司 针对肿瘤坏死因子-α的单结构域抗体及其用途
EP1900753B1 (en) * 2002-11-08 2017-08-09 Ablynx N.V. Method of administering therapeutic polypeptides, and polypeptides therefor
CN1845937A (zh) * 2003-03-24 2006-10-11 津莫吉尼蒂克斯公司 抗il-20抗体和结合伴侣以及在炎症中的使用方法
JP2007525438A (ja) * 2003-03-24 2007-09-06 ザイモジェネティクス, インコーポレイテッド 抗il−22ra抗体および結合パートナー、ならびに炎症における使用法
HUE029021T2 (en) * 2005-06-21 2017-02-28 Xoma (Us) Llc IL-1beta-binding antibodies and fragments thereof
TWI417301B (zh) * 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-22(il-22)之抗體及其用途
GB2461546B (en) * 2008-07-02 2010-07-07 Argen X Bv Antigen binding polypeptides
US8444976B2 (en) 2008-07-02 2013-05-21 Argen-X B.V. Antigen binding polypeptides
CN102770456B (zh) * 2009-12-04 2018-04-06 弗·哈夫曼-拉罗切有限公司 多特异性抗体、抗体类似物、组合物和方法
GB2476681B (en) 2010-01-04 2012-04-04 Argen X Bv Humanized camelid VH, VK and VL immunoglobulin domains
GB201002238D0 (en) * 2010-02-10 2010-03-31 Affitech As Antibodies
JP6033229B2 (ja) * 2010-11-24 2016-11-30 レクシコン ファーマシューティカルズ インコーポレイテッド Notumペクチンアセチルエステラーゼと結合する抗体

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