JP2015530087A5 - - Google Patents
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- Publication number
- JP2015530087A5 JP2015530087A5 JP2015529031A JP2015529031A JP2015530087A5 JP 2015530087 A5 JP2015530087 A5 JP 2015530087A5 JP 2015529031 A JP2015529031 A JP 2015529031A JP 2015529031 A JP2015529031 A JP 2015529031A JP 2015530087 A5 JP2015530087 A5 JP 2015530087A5
- Authority
- JP
- Japan
- Prior art keywords
- species
- human
- immune library
- target antigen
- antibody molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261695664P | 2012-08-31 | 2012-08-31 | |
| US61/695,664 | 2012-08-31 | ||
| PCT/EP2013/067979 WO2014033252A1 (en) | 2012-08-31 | 2013-08-30 | Method for producing antibody molecules having inter-species, intra-target cross-reactivity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015530087A JP2015530087A (ja) | 2015-10-15 |
| JP2015530087A5 true JP2015530087A5 (https=) | 2017-09-21 |
| JP6391574B2 JP6391574B2 (ja) | 2018-09-26 |
Family
ID=49080903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015529031A Active JP6391574B2 (ja) | 2012-08-31 | 2013-08-30 | 種間標的内交差反応性を有する抗体分子を産生する方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20150203840A1 (https=) |
| EP (2) | EP2977386A1 (https=) |
| JP (1) | JP6391574B2 (https=) |
| CN (1) | CN104583238A (https=) |
| AU (2) | AU2013310924B2 (https=) |
| CA (1) | CA2878712A1 (https=) |
| DK (1) | DK2890711T3 (https=) |
| IL (1) | IL236523B (https=) |
| IN (1) | IN2015DN00140A (https=) |
| WO (1) | WO2014033252A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2686347B1 (en) | 2011-03-16 | 2018-05-02 | argenx BVBA | Antibodies to cd70 |
| ES2860952T3 (es) | 2013-08-01 | 2021-10-05 | Univ Catholique Louvain | Proteína anti-garp y usos de la misma |
| US10391168B1 (en) | 2014-08-22 | 2019-08-27 | University Of Bern | Anti-CD70 combination therapy |
| WO2018007999A1 (en) | 2016-07-08 | 2018-01-11 | Staten Biotechnology B.V. | Anti-apoc3 antibodies and methods of use thereof |
| GB201612337D0 (en) | 2016-07-15 | 2016-08-31 | Argen-X N V | Ant-il-22r antibodies |
| CN110506056A (zh) | 2017-04-21 | 2019-11-26 | 斯塔滕生物技术有限公司 | 抗apoc3抗体和其使用方法 |
| GB201707561D0 (en) | 2017-05-11 | 2017-06-28 | Argenx Bvba | GARP-TGF-beta antibodies |
| PE20210119A1 (es) | 2017-10-31 | 2021-01-19 | Staten Biotechnology B V | Anticuerpos anti-apoc3 y metodos de uso de estos |
| AU2018383709B2 (en) | 2017-12-12 | 2025-09-11 | Pionyr Immunotherapeutics, Inc. | Anti-TREM2 antibodies and related methods |
| GB201800649D0 (en) | 2018-01-16 | 2018-02-28 | Argenx Bvba | CD70 Combination Therapy |
| WO2019151865A1 (en) | 2018-02-05 | 2019-08-08 | Stichting Vu | Inverse agonistic anti-us28 antibodies |
| WO2020080941A1 (en) | 2018-10-16 | 2020-04-23 | Umc Utrecht Holding B.V. | Anti- low-density lipoprotein receptor-related protein 5/6 antibodies |
| JP7789368B2 (ja) * | 2020-05-29 | 2025-12-22 | 学校法人 久留米大学 | 炎症性腸疾患に対する治療用抗体 |
| EP4277706A1 (en) | 2021-01-15 | 2023-11-22 | Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis | Inducers of senescence, in combination with a selective death receptor 5 (dr5) agonist, for use in a method of treating cancer |
| WO2024096735A1 (en) | 2022-10-31 | 2024-05-10 | Stichting Amsterdam UMC | Single domain anti-cd169 antibodies |
| WO2024101989A1 (en) | 2022-11-08 | 2024-05-16 | Stichting Amsterdam UMC | Activation inducible antigen receptors for adoptive immunotherapy |
| EP4631501A1 (en) | 2024-04-09 | 2025-10-15 | Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis | Combinations of a calcium homeostasis disruptor with a death receptor 5 agonist for treating cancer |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1034298T3 (da) * | 1997-12-05 | 2012-01-30 | Scripps Research Inst | Humanisering af murint antistof |
| CN1735629B (zh) * | 2002-11-08 | 2012-05-09 | 埃博灵克斯股份有限公司 | 针对肿瘤坏死因子-α的单结构域抗体及其用途 |
| EP1900753B1 (en) * | 2002-11-08 | 2017-08-09 | Ablynx N.V. | Method of administering therapeutic polypeptides, and polypeptides therefor |
| CN1845937A (zh) * | 2003-03-24 | 2006-10-11 | 津莫吉尼蒂克斯公司 | 抗il-20抗体和结合伴侣以及在炎症中的使用方法 |
| JP2007525438A (ja) * | 2003-03-24 | 2007-09-06 | ザイモジェネティクス, インコーポレイテッド | 抗il−22ra抗体および結合パートナー、ならびに炎症における使用法 |
| HUE029021T2 (en) * | 2005-06-21 | 2017-02-28 | Xoma (Us) Llc | IL-1beta-binding antibodies and fragments thereof |
| TWI417301B (zh) * | 2006-02-21 | 2013-12-01 | Wyeth Corp | 對抗人類介白素-22(il-22)之抗體及其用途 |
| GB2461546B (en) * | 2008-07-02 | 2010-07-07 | Argen X Bv | Antigen binding polypeptides |
| US8444976B2 (en) | 2008-07-02 | 2013-05-21 | Argen-X B.V. | Antigen binding polypeptides |
| CN102770456B (zh) * | 2009-12-04 | 2018-04-06 | 弗·哈夫曼-拉罗切有限公司 | 多特异性抗体、抗体类似物、组合物和方法 |
| GB2476681B (en) | 2010-01-04 | 2012-04-04 | Argen X Bv | Humanized camelid VH, VK and VL immunoglobulin domains |
| GB201002238D0 (en) * | 2010-02-10 | 2010-03-31 | Affitech As | Antibodies |
| JP6033229B2 (ja) * | 2010-11-24 | 2016-11-30 | レクシコン ファーマシューティカルズ インコーポレイテッド | Notumペクチンアセチルエステラーゼと結合する抗体 |
-
2013
- 2013-08-30 EP EP15181968.7A patent/EP2977386A1/en not_active Withdrawn
- 2013-08-30 US US14/420,039 patent/US20150203840A1/en not_active Abandoned
- 2013-08-30 EP EP13753659.5A patent/EP2890711B1/en active Active
- 2013-08-30 DK DK13753659.5T patent/DK2890711T3/en active
- 2013-08-30 CA CA2878712A patent/CA2878712A1/en not_active Abandoned
- 2013-08-30 AU AU2013310924A patent/AU2013310924B2/en active Active
- 2013-08-30 IN IN140DEN2015 patent/IN2015DN00140A/en unknown
- 2013-08-30 CN CN201380044710.8A patent/CN104583238A/zh active Pending
- 2013-08-30 WO PCT/EP2013/067979 patent/WO2014033252A1/en not_active Ceased
- 2013-08-30 JP JP2015529031A patent/JP6391574B2/ja active Active
-
2014
- 2014-12-31 IL IL236523A patent/IL236523B/en active IP Right Grant
-
2017
- 2017-06-21 AU AU2017204188A patent/AU2017204188A1/en not_active Abandoned
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