JP2015528802A5 - - Google Patents

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Publication number
JP2015528802A5
JP2015528802A5 JP2015522098A JP2015522098A JP2015528802A5 JP 2015528802 A5 JP2015528802 A5 JP 2015528802A5 JP 2015522098 A JP2015522098 A JP 2015522098A JP 2015522098 A JP2015522098 A JP 2015522098A JP 2015528802 A5 JP2015528802 A5 JP 2015528802A5
Authority
JP
Japan
Prior art keywords
her2 antibody
fucose
composition according
her2
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015522098A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015528802A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2013/065189 external-priority patent/WO2014013019A1/en
Publication of JP2015528802A publication Critical patent/JP2015528802A/ja
Publication of JP2015528802A5 publication Critical patent/JP2015528802A5/ja
Pending legal-status Critical Current

Links

JP2015522098A 2012-07-18 2013-07-18 フコシル化が低い抗her2抗体を用いた新規治療処置 Pending JP2015528802A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261673216P 2012-07-18 2012-07-18
US201261673201P 2012-07-18 2012-07-18
US201261673229P 2012-07-18 2012-07-18
US61/673,201 2012-07-18
US61/673,216 2012-07-18
US61/673,229 2012-07-18
EP12197768.0 2012-12-18
EP12197768 2012-12-18
PCT/EP2013/065189 WO2014013019A1 (en) 2012-07-18 2013-07-18 Novel therapeutic treatments with anti-her2 antibodies having a low fucosylation

Publications (2)

Publication Number Publication Date
JP2015528802A JP2015528802A (ja) 2015-10-01
JP2015528802A5 true JP2015528802A5 (https=) 2016-09-08

Family

ID=49948317

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015522098A Pending JP2015528802A (ja) 2012-07-18 2013-07-18 フコシル化が低い抗her2抗体を用いた新規治療処置

Country Status (16)

Country Link
US (1) US20150166664A1 (https=)
EP (1) EP2874658A1 (https=)
JP (1) JP2015528802A (https=)
KR (1) KR20150036710A (https=)
CN (1) CN104394887A (https=)
AU (1) AU2013291964B2 (https=)
BR (1) BR112014032169A2 (https=)
CA (1) CA2875486A1 (https=)
EA (1) EA201590237A1 (https=)
IL (1) IL236714A0 (https=)
MA (1) MA37961A1 (https=)
MX (1) MX2015000730A (https=)
NZ (1) NZ701974A (https=)
SG (1) SG11201407841YA (https=)
WO (1) WO2014013019A1 (https=)
ZA (1) ZA201408938B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU92659B1 (en) * 2015-02-23 2016-08-24 Glycotope Gmbh Glycooptimized antibody drug conjugates
CN111315776A (zh) * 2017-03-29 2020-06-19 葛莱高托普有限公司 Pd-l1和ta-muc1抗体
JP7273858B2 (ja) * 2018-06-15 2023-05-15 シャンハイ ミラコーケン インコーポレイティド 癌を治療するための方法と材料
CA3112043A1 (en) 2018-09-10 2020-03-19 Mirati Therapeutics, Inc. Combination therapies
WO2020056338A1 (en) * 2018-09-14 2020-03-19 Prelude Corporation Method of selection for treatment of subjects at risk of invasive breast cancer
CN113999313A (zh) * 2020-07-28 2022-02-01 百奥泰生物制药股份有限公司 抗her2抗体及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230769B1 (hu) 1999-01-15 2018-03-28 Genentech Inc. Módosított effektor-funkciójú polipeptid-változatok
EP1176195B1 (en) 1999-04-09 2013-05-22 Kyowa Hakko Kirin Co., Ltd. Method for controlling the activity of immunologically functional molecule
EP2322644A1 (en) 2000-06-28 2011-05-18 GlycoFi, Inc. Methods for producing modified glycoproteins
HUP0600342A3 (en) 2001-10-25 2011-03-28 Genentech Inc Glycoprotein compositions
CA2481920A1 (en) 2002-04-09 2003-10-16 Kyowa Hakko Kogyo Co., Ltd. Antibody composition-containing medicament
CN103540600B (zh) * 2003-01-22 2017-12-01 罗氏格黎卡特股份公司 融合构建体及其用来生产Fc受体结合亲和性和效应子功能提高的抗体的用途
FR2858235B1 (fr) 2003-07-31 2006-02-17 Lab Francais Du Fractionnement Utilisation d'anticorps optimises en adcc pour traiter les patients faibles repondeurs
WO2005053742A1 (ja) * 2003-12-04 2005-06-16 Kyowa Hakko Kogyo Co., Ltd. 抗体組成物を含有する医薬
WO2005086875A2 (en) * 2004-03-11 2005-09-22 City Of Hope A humanized anti-cea t84.66 antibody and uses thereof
DOP2006000029A (es) * 2005-02-07 2006-08-15 Genentech Inc Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
SI2073842T1 (sl) * 2006-09-10 2015-05-29 Glycotope Gmbh Uporaba človeških celic izvirajočih iz mieloične levkemije za izražanje protiteles
WO2011044368A1 (en) * 2009-10-07 2011-04-14 Macrogenics, Inc. Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use
US20120258496A1 (en) * 2010-09-27 2012-10-11 Boehringer Ingelheim International Gmbh Production of low fucose antibodies in h4-ii-e rat cells

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