JP2015519311A - Il−17アンタゴニストを用いて強直性脊椎炎を治療する方法 - Google Patents

Il−17アンタゴニストを用いて強直性脊椎炎を治療する方法 Download PDF

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Publication number
JP2015519311A
JP2015519311A JP2015507163A JP2015507163A JP2015519311A JP 2015519311 A JP2015519311 A JP 2015519311A JP 2015507163 A JP2015507163 A JP 2015507163A JP 2015507163 A JP2015507163 A JP 2015507163A JP 2015519311 A JP2015519311 A JP 2015519311A
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Prior art keywords
patient
allele
antagonist
level
erap1
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Japanese (ja)
Inventor
ベク,ステファン
ブラチャト,アーント
ヒュベール,ウォルフギャング
リー,ヤリ
ワン,イン
イエレンスキー,ロマン
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ノバルティス アーゲー
ノバルティス アーゲー
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
JP2015507163A 2012-04-20 2013-04-18 Il−17アンタゴニストを用いて強直性脊椎炎を治療する方法 Pending JP2015519311A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261636062P 2012-04-20 2012-04-20
US61/636,062 2012-04-20
PCT/US2013/037068 WO2013158821A2 (en) 2012-04-20 2013-04-18 Methods of treating ankylosing spondylitis using il-17 antagonists

Publications (1)

Publication Number Publication Date
JP2015519311A true JP2015519311A (ja) 2015-07-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015507163A Pending JP2015519311A (ja) 2012-04-20 2013-04-18 Il−17アンタゴニストを用いて強直性脊椎炎を治療する方法

Country Status (13)

Country Link
US (1) US20150125462A1 (zh)
EP (1) EP2838560A2 (zh)
JP (1) JP2015519311A (zh)
KR (1) KR20150010709A (zh)
CN (1) CN104244979A (zh)
AR (1) AR090738A1 (zh)
AU (1) AU2013249232A1 (zh)
BR (1) BR112014025768A2 (zh)
CA (1) CA2870025A1 (zh)
MX (1) MX2014012640A (zh)
RU (1) RU2014146594A (zh)
TW (1) TW201347771A (zh)
WO (1) WO2013158821A2 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018537418A (ja) * 2015-10-19 2018-12-20 ノバルティス アーゲー インターロイキン17(il−17)アンタゴニストを用いてx線陰性体軸性脊椎関節炎を治療する方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014155278A2 (en) * 2013-03-26 2014-10-02 Novartis Ag Methods of treating autoimmune diseases using il-17 antagonists
EP3167892A1 (en) 2015-11-10 2017-05-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for preventing or treating imflammatory bowel diseases
KR20180067676A (ko) 2015-10-27 2018-06-20 유씨비 바이오파마 에스피알엘 항-il-17a/f 항체를 사용한 치료 방법
JP2021501752A (ja) * 2017-11-02 2021-01-21 ノバルティス アーゲー インターロイキン−17(il−17)アンタゴニストを使用して腱障害を治療する方法
US11894121B2 (en) 2021-08-06 2024-02-06 Reviv Global Ltd Prescriptive nutrition-based IV and IM infusion treatment formula creation systems and methods
US11600375B2 (en) 2021-07-30 2023-03-07 Reviv Global Ltd Genetically personalized food recommendation systems and methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0417487D0 (en) 2004-08-05 2004-09-08 Novartis Ag Organic compound
GB0425569D0 (en) 2004-11-19 2004-12-22 Celltech R&D Ltd Biological products
PL2481753T3 (pl) 2005-12-13 2018-09-28 Eli Lilly And Company Przeciwciała anty-IL-17
WO2007117749A2 (en) 2006-01-31 2007-10-18 Novartis Ag Il-17 antagonistic antibodies fpr treating cancer
GB0612928D0 (en) 2006-06-29 2006-08-09 Ucb Sa Biological products
ES2493042T3 (es) 2008-09-29 2014-09-11 Roche Glycart Ag Anticuerpos contra la IL-17 humana y usos de los mismos

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018537418A (ja) * 2015-10-19 2018-12-20 ノバルティス アーゲー インターロイキン17(il−17)アンタゴニストを用いてx線陰性体軸性脊椎関節炎を治療する方法
JP2021100956A (ja) * 2015-10-19 2021-07-08 ノバルティス アーゲー インターロイキン17(il−17)アンタゴニストを用いてx線陰性体軸性脊椎関節炎を治療する方法
JP7389077B2 (ja) 2015-10-19 2023-11-29 ノバルティス アーゲー インターロイキン17(il-17)アンタゴニストを用いてx線陰性体軸性脊椎関節炎を治療する方法

Also Published As

Publication number Publication date
TW201347771A (zh) 2013-12-01
AR090738A1 (es) 2014-12-03
BR112014025768A2 (pt) 2017-07-04
KR20150010709A (ko) 2015-01-28
WO2013158821A3 (en) 2014-03-13
US20150125462A1 (en) 2015-05-07
MX2014012640A (es) 2015-01-15
EP2838560A2 (en) 2015-02-25
AU2013249232A1 (en) 2014-10-09
CN104244979A (zh) 2014-12-24
CA2870025A1 (en) 2013-10-24
RU2014146594A (ru) 2016-06-10
WO2013158821A2 (en) 2013-10-24

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