JP2015515266A5 - - Google Patents
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- JP2015515266A5 JP2015515266A5 JP2015500578A JP2015500578A JP2015515266A5 JP 2015515266 A5 JP2015515266 A5 JP 2015515266A5 JP 2015500578 A JP2015500578 A JP 2015500578A JP 2015500578 A JP2015500578 A JP 2015500578A JP 2015515266 A5 JP2015515266 A5 JP 2015515266A5
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- Prior art keywords
- chromosome
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261610422P | 2012-03-13 | 2012-03-13 | |
| US61/610,422 | 2012-03-13 | ||
| PCT/US2013/031082 WO2013138527A1 (en) | 2012-03-13 | 2013-03-13 | Methods for analyzing massively parallel sequencing data for noninvasive prenatal diagnosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015515266A JP2015515266A (ja) | 2015-05-28 |
| JP2015515266A5 true JP2015515266A5 (https=) | 2015-12-10 |
| JP6411995B2 JP6411995B2 (ja) | 2018-10-24 |
Family
ID=49158429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015500578A Active JP6411995B2 (ja) | 2012-03-13 | 2013-03-13 | 非侵襲的出生前診断のために大量並列シークエンシング・データを分析する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9218449B2 (https=) |
| EP (2) | EP3573066B1 (https=) |
| JP (1) | JP6411995B2 (https=) |
| AU (1) | AU2013232123B2 (https=) |
| CA (1) | CA2866324C (https=) |
| WO (1) | WO2013138527A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140235474A1 (en) | 2011-06-24 | 2014-08-21 | Sequenom, Inc. | Methods and processes for non invasive assessment of a genetic variation |
| WO2013052907A2 (en) | 2011-10-06 | 2013-04-11 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US9367663B2 (en) | 2011-10-06 | 2016-06-14 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10196681B2 (en) | 2011-10-06 | 2019-02-05 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10424394B2 (en) | 2011-10-06 | 2019-09-24 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US9984198B2 (en) | 2011-10-06 | 2018-05-29 | Sequenom, Inc. | Reducing sequence read count error in assessment of complex genetic variations |
| CA2861856C (en) | 2012-01-20 | 2020-06-02 | Sequenom, Inc. | Diagnostic processes that factor experimental conditions |
| US9920361B2 (en) | 2012-05-21 | 2018-03-20 | Sequenom, Inc. | Methods and compositions for analyzing nucleic acid |
| US10504613B2 (en) | 2012-12-20 | 2019-12-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10497461B2 (en) | 2012-06-22 | 2019-12-03 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10482994B2 (en) | 2012-10-04 | 2019-11-19 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US20130309666A1 (en) | 2013-01-25 | 2013-11-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10930368B2 (en) | 2013-04-03 | 2021-02-23 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| KR102665592B1 (ko) | 2013-05-24 | 2024-05-21 | 시쿼넘, 인코포레이티드 | 유전적 변이의 비침습 평가를 위한 방법 및 프로세스 |
| ES3037160T3 (en) | 2013-06-21 | 2025-09-29 | Sequenom Inc | Methods and processes for non-invasive assessment of genetic variations |
| KR102384620B1 (ko) | 2013-10-04 | 2022-04-11 | 시쿼넘, 인코포레이티드 | 유전적 변이의 비침습 평가를 위한 방법 및 프로세스 |
| CN105874082B (zh) | 2013-10-07 | 2020-06-02 | 塞昆纳姆股份有限公司 | 用于非侵入性评估染色体改变的方法和过程 |
| CN105830077B (zh) * | 2013-10-21 | 2019-07-09 | 维里纳塔健康公司 | 用于在确定拷贝数变异中改善检测的灵敏度的方法 |
| AU2014346562B2 (en) | 2013-11-07 | 2018-11-29 | The Board Of Trustees Of The Leland Stanford Junior University | Cell-free nucleic acids for the analysis of the human microbiome and components thereof |
| EP3690061B1 (en) | 2014-05-30 | 2025-01-01 | Verinata Health, Inc. | Detecting, optionally fetal, sub-chromosomal aneuploidies and copy number variations |
| EP4358097A1 (en) | 2014-07-25 | 2024-04-24 | University of Washington | Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same |
| US11783911B2 (en) | 2014-07-30 | 2023-10-10 | Sequenom, Inc | Methods and processes for non-invasive assessment of genetic variations |
| EP3502273B1 (en) | 2014-12-12 | 2020-07-08 | Verinata Health, Inc. | Cell-free dna fragment |
| JP6873921B2 (ja) | 2015-05-18 | 2021-05-19 | カリウス・インコーポレイテッド | 核酸の集団を濃縮するための組成物および方法 |
| KR101678962B1 (ko) * | 2015-08-21 | 2016-12-06 | 이승재 | 대규모 병렬형 게놈서열분석 방법을 이용한 비침습적 산전검사 장치 및 방법 |
| US10095831B2 (en) | 2016-02-03 | 2018-10-09 | Verinata Health, Inc. | Using cell-free DNA fragment size to determine copy number variations |
| EP3978627A1 (en) | 2016-03-25 | 2022-04-06 | Karius, Inc. | Methods using synthetic nucleic acid spike-ins |
| WO2018009723A1 (en) * | 2016-07-06 | 2018-01-11 | Guardant Health, Inc. | Methods for fragmentome profiling of cell-free nucleic acids |
| CA3030890A1 (en) | 2016-07-27 | 2018-02-01 | Sequenom, Inc. | Genetic copy number alteration classifications |
| CA3207879A1 (en) | 2017-01-24 | 2018-08-02 | Sequenom, Inc. | Methods and processes for assessment of genetic variations |
| JP7370862B2 (ja) | 2017-03-17 | 2023-10-30 | セクエノム， インコーポレイテッド | 遺伝子モザイク症のための方法およびプロセス |
| WO2018191563A1 (en) | 2017-04-12 | 2018-10-18 | Karius, Inc. | Sample preparation methods, systems and compositions |
| CN111526793A (zh) | 2017-10-27 | 2020-08-11 | 朱诺诊断学公司 | 用于超低体积液体活检的设备、系统和方法 |
| CN108733979A (zh) * | 2017-10-30 | 2018-11-02 | 成都凡迪医疗器械有限公司 | Nipt的gc含量校准方法、装置及计算机可读存储介质 |
| US12590326B2 (en) | 2018-01-10 | 2026-03-31 | Guardant Health, Inc. | Methods for fragmentome profiling of cell-free nucleic acids |
| CA3082601A1 (en) | 2018-03-16 | 2019-09-19 | Karius, Inc. | Sample series to differentiate target nucleic acids from contaminant nucleic acids |
| US12462935B2 (en) | 2018-03-30 | 2025-11-04 | Nucleix Ltd. | Deep learning-based methods, devices, and systems for prenatal testing |
| EP4700161A3 (en) | 2018-11-21 | 2026-03-11 | Karius, Inc. | Direct-to-library methods, systems, and compositions |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| CN115938473A (zh) * | 2022-01-20 | 2023-04-07 | 重庆师范大学 | 一种化学计量基因组基础分析的计算方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6927028B2 (en) | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
| AT412476B (de) * | 2002-09-24 | 2005-03-25 | Forsch Krebskranke Kinder | Verfahren zur herstellung eines virtuellen chromosoms |
| US7371525B2 (en) | 2003-07-29 | 2008-05-13 | The Chinese University Of Hong Kong | Compositions and methods for diagnosing and treating severe acute respiratory syndrome (SARS) |
| CA3007182A1 (en) | 2005-03-18 | 2006-09-21 | The Chinese University Of Hong Kong | Markers for prenatal diagnosis, monitoring or predicting preeclampsia |
| US7901884B2 (en) | 2006-05-03 | 2011-03-08 | The Chinese University Of Hong Kong | Markers for prenatal diagnosis and monitoring |
| US7754428B2 (en) | 2006-05-03 | 2010-07-13 | The Chinese University Of Hong Kong | Fetal methylation markers |
| WO2009012283A1 (en) | 2007-07-17 | 2009-01-22 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| US12180549B2 (en) | 2007-07-23 | 2024-12-31 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using genomic sequencing |
| CA3069082C (en) | 2008-09-20 | 2022-03-22 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| US8563242B2 (en) | 2009-08-11 | 2013-10-22 | The Chinese University Of Hong Kong | Method for detecting chromosomal aneuploidy |
| EP3783110B1 (en) | 2009-11-05 | 2022-11-23 | The Chinese University Of Hong Kong | Fetal genomic analysis from a maternal biological sample |
| CA2780016C (en) * | 2009-11-06 | 2017-09-19 | The Chinese University Of Hong Kong | Size-based genomic analysis |
| US8725422B2 (en) | 2010-10-13 | 2014-05-13 | Complete Genomics, Inc. | Methods for estimating genome-wide copy number variations |
-
2013
- 2013-03-13 CA CA2866324A patent/CA2866324C/en active Active
- 2013-03-13 EP EP19174472.1A patent/EP3573066B1/en active Active
- 2013-03-13 AU AU2013232123A patent/AU2013232123B2/en active Active
- 2013-03-13 US US13/802,268 patent/US9218449B2/en active Active
- 2013-03-13 WO PCT/US2013/031082 patent/WO2013138527A1/en not_active Ceased
- 2013-03-13 JP JP2015500578A patent/JP6411995B2/ja active Active
- 2013-03-13 EP EP13760635.6A patent/EP2825991B1/en active Active
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