JP2015513349A - 組織修復のための基礎材システム - Google Patents
組織修復のための基礎材システム Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
- D04H1/4391—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece characterised by the shape of the fibres
- D04H1/43918—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece characterised by the shape of the fibres nonlinear fibres, e.g. crimped or coiled fibres
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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- D01D5/0015—Electro-spinning characterised by the initial state of the material
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- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/70—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres
- D04H1/72—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged
- D04H1/728—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged by electro-spinning
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- A—HUMAN NECESSITIES
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Abstract
Description
基礎材の基礎材処理は、基礎材を反応性ガスにより形成されるプラズマにさらすことを含んでもよい。反応性ガスは、酸素、窒素、アルゴン、アンモニアまたはその組み合わせを含んでもよい。
PTFE包覆ステント(心房I−cast,9mm)を、7Fの導入器シースを通して挿入した。バルーンを10秒間15ATMまで膨張し、その後収縮させ取り除いた。それから第2のバルーン(パワーフレックスP3 CTAカテーテル12mm×4mm)を置き、10秒間12ATMまで近位および遠位に膨張させた。6FのMP−1カテーテルを再度置き、血管造影を使用してAAAが適切に閉塞したかどうかを判断した。それから、大腿動脈が絹縫合素材を用いて連結されたとき、ガイドワイヤおよびカテーテル、続いてシースを取り除いた。アクセス部位を3−0Vicrylで閉じ、動物を回復させた。
Claims (27)
- 拡張可能な基礎材を備え、前記基礎材は不織繊維で構成され、前記基礎材は実質的に曲線状の繊維を有する第1の面、および実質的に直線状の繊維を有する第2の面を有し、
前記基礎材が哺乳類内に位置決められるとき、前記基礎材の前記第1の面は細胞の付着に適切な面を提供し、一方で前記基礎材の前記第2の面は細胞の侵入および組織化を促進する、
組織修復装置。 - 前記装置が動脈瘤の修復のために構成される、請求項1に記載の装置。
- 前記装置が、内腔組織構造、組織内の空洞または半空洞のスペースの修復のために構成される、請求項1に記載の装置。
- 前記繊維が電界紡糸される、請求項1に記載の装置。
- 前記繊維が、押出、延伸、および/または引抜技術を用いて製造される、請求項1に記載の装置。
- 前記繊維が、生分解性および/または生体吸収性素材で構成される、請求項1に記載の装置。
- 基礎材が、1つまたは複数のポリ(α−ヒドロキシエステル)で構成される、請求項1に記載の装置。
- 基礎材がポリカプロラクトンで構成される、請求項1に記載の装置。
- 前記基礎材が、生分解性および/または生体吸収性の天然ポリマーで構成される、請求項1に記載の装置。
- 前記基礎材が、エラスチン、コラーゲン、DNA、RNA、グルコサミノグルカンまたはその混合物で構成される、請求項1に記載の装置。
- 前記第1の面が凹面であり、前記第2の面が凸面である、請求項1に記載の装置。
- 前記基礎材が支持構造により支持される、請求項1に記載の装置。
- 前記支持構造が拡張可能である、請求項8に記載の装置。
- 前記支持構造が拡張可能なステントである、請求項8に記載の装置。
- 前記支持構造が柔軟な構造である、請求項8に記載の装置。
- 前記支持構造が再配置可能な構造である、請求項8に記載の装置。
- 前記支持構造が生体吸収性および/または生分解性である、請求項8に記載の装置。
- 前記基礎材が、生分解性素材および/または生体吸収性素材化合物から電界紡糸される不織マイクロファイバで構成される、請求項1に記載の装置。
- 前記基礎材が、生分解性素材および/または生体吸収性素材化合物から電界紡糸される不織ナノファイバで構成される、請求項1に記載の装置。
- 前記基礎材が実質的にチューブ状である、請求項1に記載の装置。
- 前記基礎材が、医療装置の少なくとも一部により支持される、請求項1に記載の装置。
- 前記基礎材が、支持構造に縫合または機械的に固定される、請求項1に記載の装置。
- 前記基礎材が支持構造に化学的に接着される、請求項1に記載の装置。
- 前記基礎材が、支持構造上に直接または間接的に電界紡糸される、請求項1に記載の装置。
- 前記支持構造が、電界紡糸された前記基礎材内に組み込まれる、請求項1に記載の装置。
- 装置を内腔組織構造内に挿入し、前記装置は拡張可能な基礎材を備え、前記基礎材は生分解性素材および/または生体吸収性素材から電界紡糸された不織繊維で構成され、前記基礎材は、実質的に曲線状の繊維を有する第1の面、および実質的に直線状の繊維を有する第2の面を備えるステップと、
前記基礎材が前記内腔組織構造の少なくとも一部と接触するように、前記基礎材を拡張し、前記基礎材の第1の面が細胞の付着に適切な面を提供し、一方で前記第2の表面が細胞の侵入および組織化を促進するように前記基礎材が位置決められるステップと、
前記内腔組織構造内に前記装置を固定するステップと、を含む、
組織修復方法。 - 拡張可能な基礎材を備え、前記基礎材は、実質的に曲線状の繊維を有する面、および実質的に直線状の繊維を有する対向する面で構成される、
医学的状態を治療する装置。
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US20180200084A1 (en) | 2018-07-19 |
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