JP2015113334A - Bathing agent - Google Patents

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JP2015113334A
JP2015113334A JP2013259160A JP2013259160A JP2015113334A JP 2015113334 A JP2015113334 A JP 2015113334A JP 2013259160 A JP2013259160 A JP 2013259160A JP 2013259160 A JP2013259160 A JP 2013259160A JP 2015113334 A JP2015113334 A JP 2015113334A
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peel
dried
dry
bathing agent
drying method
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JP6355917B2 (en
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正章 吾妻
Masaaki Azuma
正章 吾妻
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JABARA LAB KK
JABARA LABORATORY KK
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JABARA LABORATORY KK
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Abstract

PROBLEM TO BE SOLVED: To provide a bathing agent which is highly effective in alleviating the symptoms of atopic dermatitis or allergic dermatitis, and is also friendly to environment.SOLUTION: The bathing agent of this invention is equipped with Citrus Jabara dry peel and a holding bag with water permeability for containing Citrus Jabara dry peel. And the Citrus Jabara dry peel of the bathing agent of this invention can be illustrated by products dried with a heat-drying method, a freeze-drying method, a spray-drying method, and the like, or peel powders produced from the same.

Description

この発明は、じゃばら乾燥果皮を有効成分とする入浴剤に関する。   The present invention relates to a bath preparation containing dried rose peel as an active ingredient.

じゃばらは、日本国和歌山県北山村だけに自生するユズやダイダイ、カボスの仲間の柑橘類であり、果汁を多く含み、糖度と酸度のバランスがとれ、まろやかな風味を備えた果実である。   Jabala is a citrus fruit that is naturally grown only in Kitayama Village, Wakayama Prefecture, Japan. It is a citrus fruit that is rich in fruit juice, balanced in sugar and acidity, and has a mellow flavor.

また、じゃばらは、生薬として使用される陳皮や柚子のように優れた温熱効果を供えていると考えられており、従来から、じゃばらの抽出物を含む浴剤組成物などが考えられている(特許文献1及び特許文献2を参照。)。   In addition, jabara is considered to provide an excellent thermal effect, such as a skin or cocoon used as a herbal medicine, and conventionally, a bath agent composition containing an extract of jabara has been considered ( (See Patent Literature 1 and Patent Literature 2.)

しかし、じゃばら抽出物を含有する浴剤組成物は、抗アレルギー作用を有するナリルチン等の有効成分の含有量が少なく、アトピー性皮膚炎やアレルギー性皮膚炎の症状を軽減する効果が不充分であった。また、有効成分を抽出するため、水や有機溶媒などの溶媒が必要であり、これによって余計なコストや環境に負荷がかかるという問題点があった。   However, a bath preparation composition containing a rose extract has a low content of active ingredients such as nariltin having antiallergic action, and is insufficient in reducing the symptoms of atopic dermatitis and allergic dermatitis. It was. Moreover, in order to extract an active ingredient, solvents, such as water and an organic solvent, are needed, and this had the problem that extra cost and an environment load were added.

なお、じゃばらの果汁はナリルチンを含んでいるため、これを飲み続けることによって抗アレルギー作用、具体的には抗花粉症作用があることが既に確認されている(非特許文献1を参照。)。また、発明者は、特定の方法で調製したじゃばら乾燥果皮が、じゃばら果汁よりも優れた抗花粉症作用等を備えていることを既に発見しており、これを特許出願のうえ、権利化している(特許文献3を参照。)。   In addition, since the fruit juice of jar contains nariltin, it has already been confirmed that it has anti-allergic action, specifically, anti-hay fever action by continuing to drink it (see Non-Patent Document 1). In addition, the inventor has already discovered that dried rose peel prepared by a specific method has an anti-hay fever action and the like superior to rose juice, which has been granted a patent after filing a patent application. (See Patent Document 3).

特開平7−179329号公報JP-A-7-179329 特表2011−510980号公報Special table 2011-510980 gazette 特開2012−111743号公報JP 2012-111743 A

月刊「臨床免疫・アレルギー科」,50(3):360-364,2008Monthly “Clinical Immunology and Allergy”, 50 (3): 360-364, 2008

そこで、この発明は、アトピー性皮膚炎やアレルギー性皮膚炎の症状を軽減する効果が高く、環境にも優しい入浴剤を提供することを目的とする。   Therefore, an object of the present invention is to provide a bath agent that is highly effective in reducing the symptoms of atopic dermatitis and allergic dermatitis and is environmentally friendly.

発明者は、鋭意検討の結果、じゃばらの乾燥果皮を入浴剤に使用することによって、アトピー性皮膚炎やアレルギー性皮膚炎の症状の軽減できることを見出し、この発明を完成させた。   As a result of intensive studies, the inventor has found that the use of dried dry peel as a bath agent can reduce the symptoms of atopic dermatitis and allergic dermatitis, and has completed the present invention.

すなわち、この出願の請求項1に記載の入浴剤は、じゃばら乾燥果皮と、じゃばら乾燥果皮を収容し、透水性を有する収容袋とを備えているものである。また、請求項2に記載の入浴剤は、請求項1に記載の入浴剤であって、じゃばら果皮を熱乾燥法、フリーズドライ法、スプレードライ法の何れかによって乾燥するものである。また、請求項3に記載の入浴剤は、請求項2に記載の入浴剤であって、じゃばら果皮をフリーズドライ法によって乾燥したのち、熱乾燥法によって乾燥するものである。さらに、請求項4に記載の入浴剤は、請求項3に記載の入浴剤であって、80℃で熱乾燥するものである。加えて、請求項5に記載の入浴剤は、請求項1から請求項4の何れかに記載の入浴剤であって、じゃばら乾燥果皮が果皮末のものである。   That is, the bathing agent according to claim 1 of this application is provided with a dry dried peel and a containing bag containing the dry dried peel and having water permeability. The bathing agent according to claim 2 is the bathing agent according to claim 1, and dries the peels by any one of a heat drying method, a freeze drying method and a spray drying method. Moreover, the bathing agent according to claim 3 is the bathing agent according to claim 2, wherein the bark peel is dried by a freeze drying method and then dried by a heat drying method. Furthermore, the bathing agent according to claim 4 is the bathing agent according to claim 3, which is heat-dried at 80 ° C. In addition, the bathing agent according to claim 5 is the bathing agent according to any one of claims 1 to 4, wherein the dry dried peel is of the end of the skin.

この発明の入浴剤は、アトピー性皮膚炎やアレルギー性皮膚炎の症状を軽減する効果に優れている。また、従来は焼却廃棄されていたじゃばら果皮が利用できるため、環境にも優しい。   The bath agent of this invention is excellent in the effect of reducing the symptoms of atopic dermatitis and allergic dermatitis. In addition, it is environmentally friendly because it can use the peels that had been discarded by incineration.

この発明の入浴剤は、じゃばら乾燥果皮と、じゃばら乾燥果皮を収容して透水性を有する収容袋とを備えるものである。そこで、この発明の構成要素であるじゃばら乾燥果皮、収納袋などについて以下に詳説する。   The bath agent of the present invention comprises a dry dried peel and a containing bag that contains the dry dried peel and has water permeability. Therefore, the dry rose peel, storage bag, and the like, which are constituent elements of the present invention, will be described in detail below.

1.じゃばら乾燥果皮
(1)じゃばら果実
この発明で使用するじゃばら果実は、特に限定することなく使用できる。中でも、単位重量当たりのナリルチンの含有量が多いことから、摘果された果実や果皮が黄変する以前の未成熟段階の果実が好ましい。ここで、未成熟段階の果実とは、具体的には、着果から3月〜4月後に摘果した果実が好ましい。なお、じゃばらは、一般的に6月ごろに着果することから、9月〜10月ごろに収穫された果実が好ましい。
1. Jabal dried pericarp (1) Jabal fruit Jabal fruit used in the present invention can be used without any particular limitation. Especially, since there is much content of the narirutin per unit weight, the fruit of the immature stage before yellowing of the fruit and fruit peel which were picked is preferable. Here, specifically, the immature stage fruit is preferably a fruit that has been harvested three to four months after fruit set. In addition, since potatoes generally fruit around June, fruits harvested around September to October are preferable.

(2)じゃばら果皮
じゃばら果皮は、じゃばら果実から手で剥いたもの、公知の自動皮むき機により剥いたもの、果汁圧搾機により果汁を搾った後に残る残渣などが使用できるが、手間を考えると果汁圧搾機の残渣が好ましい。
(2) Jara pericarp Jara pericarp can be peeled off by hand from the perilla fruit, peeled off by a known automatic peeler, or residue left after squeezing the fruit juice from the fruit juice press. The residue of a fruit juice press is preferred.

(3)乾燥方法
じゃばら乾燥果皮は、一般的な方法、すなわち、果皮をそのまま又は細切したのち、日陰、陽干しする自然乾燥法、乾燥機によって乾燥する熱乾燥法、フリーズドライ法、スプレードライ法又はこれらの方法を組み合わせて製造したものが、例示できる。
(3) Drying method The dry dried peel is a general method, that is, after the skin is cut or shredded, then shaded, dried naturally, dried by a dryer, freeze dried, freeze dried, spray dried Examples thereof are those prepared by combining these methods or these methods.

中でも、フリーズドライ法で乾燥したのち、熱乾燥法によって乾燥することによって製造したものが好ましく、80℃で熱乾燥したものが好ましい。このようにして製造したじゃばら乾燥果皮は、高いナリルチン濃度を維持したまま、酸化されるとアレルギー誘発物質になるリモネンが完全に除去されている。そのため、この発明の入浴剤自身によるアレルギー等が発症する可能性をほぼ完全に無くすことができる。   Among these, those produced by drying by freeze drying and then drying by heat drying are preferred, and those dried by heating at 80 ° C. are preferred. Limonene, which is an allergen when it is oxidized, is completely removed from the dried dry peel of the rose thus produced while maintaining a high concentration of naliltin. Therefore, the possibility of developing allergies or the like due to the bath agent of the present invention can be almost completely eliminated.

また、この乾燥果皮は乾燥した形状のままでも使用できるが、ナリルチンを浴槽中の温水に溶出し易くするため、一般的な方法、例えば、手で切り分けて細片化したり、ボールミル等により果皮末に加工してから使用することが好ましい。   The dried pericarp can be used in a dry form, but in order to make it easier to elute narirutin into the hot water in the bathtub, the pericarp powder can be separated by a general method, for example, by hand, or by a ball mill. It is preferable to use it after processing it.

果皮末に加工する際の粉末の大きさは、3.5〜20メッシュのものが好ましく、3.5〜10メッシュのものがより好ましい。粉末が3.5メッシュの篩を通らないほど大きければ、ナリルチンの温水への溶出効果が限定され、粉末が20メッシュの篩を通り抜けるほど小さければ一般的な収容袋から漏れ出す可能性があるからである。   The size of the powder when processed into a peel is preferably 3.5 to 20 mesh, more preferably 3.5 to 10 mesh. If the powder is so large that it does not pass through a 3.5 mesh sieve, the elution effect of nariltin in hot water is limited, and if the powder is so small that it passes through a 20 mesh sieve, it may leak out from a general storage bag. It is.

2.収納袋
収容袋は、じゃばら乾燥果皮が浴槽中に流出して温水を汚染することを抑制するために収容するとともに、じゃばら乾燥果皮からナリルチンが溶出できるように透水性を有する袋形状のものである。収納袋の形状は特に限定することなく任意の形状を取れるが、製造し易さなどから略長方形が好ましい。
2. Storage bag The storage bag is stored in order to prevent the dry dried fruit peel from flowing into the bathtub and contaminating the hot water, and the bag has a water permeability so that nariltin can be eluted from the dry dry peel. It is. The shape of the storage bag is not particularly limited, and can be any shape. However, a rectangular shape is preferable from the standpoint of ease of manufacture.

また、収容袋の周囲は、密封してもよく、収納するじゃばら乾燥果皮を交換できるように、その一部が紐などで開閉自在な構成にしてもよい。例えば、縦15cm、横10cmの略長方形であり、じゃばら乾燥果皮を収容したのちその周囲が密封された収納袋が挙げられる。   Further, the periphery of the storage bag may be sealed, and a part of the storage bag may be configured to be openable and closable with a string or the like so that the stored dry peel can be exchanged. For example, a storage bag having a substantially rectangular shape with a length of 15 cm and a width of 10 cm, in which dried dry skin is stored and then the periphery thereof is sealed can be mentioned.

収容袋の素材としては、通水性のある素材であれば特に限定することなく使用できるが、じゃばら乾燥果皮で浴槽中のお湯を汚さないように、お湯中で破れない程度の強度があるとともに、柔軟性、可撓性のある素材が好ましい。   The material of the containment bag can be used without any limitation as long as it is water-permeable material, but it has a strength that does not break in hot water so that the hot water in the bathtub is not soiled with the dry dried peel, A material having flexibility and flexibility is preferable.

具体的には、例えば、ナイロンストッキング等のストッキング素材と同様の素材、ポリエチレンテレフタレート、ポリアミド、ポリエチレン等の繊維素材を織加工したものや不織布としたもの、ティーバッグ様の紙袋などが挙げられる。中でも、入手し易すく安価なことから、ポリエチレンテレフタレート繊維等からなる不織布が好ましい。   Specifically, for example, a material similar to a stocking material such as nylon stockings, a woven fabric or a non-woven fabric of a fiber material such as polyethylene terephthalate, polyamide, polyethylene, or a tea bag-like paper bag may be used. Among these, non-woven fabric made of polyethylene terephthalate fiber is preferable because it is easily available and inexpensive.

3.その他
この発明の入浴剤は、じゃばら乾燥果皮のほか、効果の妨げにならない範囲で、公知の植物粉末及び生薬(エキス、粉末)、無機塩類、香料類、色素等を添加してもよい。
3. Others The bathing agent of the present invention may contain known plant powders and herbal medicines (extracts, powders), inorganic salts, fragrances, pigments, etc., as long as the effect is not hindered in addition to the dry peel.

植物粉末及び生薬類としては、レモンの皮、月桃、海藻、スピルリナ、クロロフィル、ドナリエラ、ヒノキ、ヒバ、米ヌカ、シュウブ、ショウキョウ、カンゾウ、チンピ、トウヒ、トウキ、ハッカ、ケイヒ、ウバイ、ヨモギ、ドクダミ、モモノハ、カミツレ、アロエ、ジャスミン、ローズヒップ、ラベンダー、グァバ、オウゴン、クコ、レイシ、ニワトコ、アシタバ、ウコギ、ゴボウ、コウカ、ゲンノショウコ、ショウキョウ等の粉砕物及びその水溶性もしくは油溶性抽出液が挙げられる。なお、抽出液を使用する場合には、抽出液を他の成分と混合後乾燥させて使用すればよい。   Plant powders and herbal medicines include lemon peel, moon peach, seaweed, spirulina, chlorophyll, donariella, cypress, hiba, rice bran, shobu, shrimp, licorice, chimpi, spruce, touki, mint, keihi, buckwheat, mugwort , Groundnut, momonoha, chamomile, aloe, jasmine, rosehip, lavender, guava, ugone, wolfberry, lychee, elderberry, ashitaba, okogi, burdock, mulberry, geno shoko, ginger, etc. and its water-soluble or oil-soluble extraction Liquid. In addition, what is necessary is just to dry and use an extract after mixing with another component when using an extract.

無機塩類としては、塩化ナトリウム、炭酸水素ナトリウム、炭酸ナトリウム、ホウ酸、ほう砂、硫酸ナトリウム、硫化ナトリウム、硫化カリウム、硝酸ナトリウム、硝酸カルシウム、硫酸アンモニウム、チオ硫酸ナトリウム、リン酸水素カルシウム、塩化カリウム、塩化アンモニウム、リン酸ナトリウム、次亜硫酸ナトリウム、チオ硫酸カルシウム、硫黄、尿素、セスキ炭酸ナトリウム、硫酸マグネシウム、ミョウバン等が挙げられる。   Inorganic salts include sodium chloride, sodium bicarbonate, sodium carbonate, boric acid, borax, sodium sulfate, sodium sulfide, potassium sulfide, sodium nitrate, calcium nitrate, ammonium sulfate, sodium thiosulfate, calcium hydrogen phosphate, potassium chloride, Examples include ammonium chloride, sodium phosphate, sodium hyposulfite, calcium thiosulfate, sulfur, urea, sodium sesquicarbonate, magnesium sulfate, and alum.

香料類としては、ラベンダー油、ジャスミン油、ローズ油、レモン油、オレンジ油、ハッカ油、タイム油、ショウブ油、ウイキョウ油、スギ油、ヒバ油、ヒノキ油、バラ油、ユーカリ油、カンファー、ペパーミント油、スペアミント油、ゲラニオール、ミカン油、トウヒ、シトロネロール等の天然及び合成香料等が挙げられる。   Perfumes include lavender oil, jasmine oil, rose oil, lemon oil, orange oil, mint oil, thyme oil, ginger oil, fennel oil, cedar oil, hiba oil, cypress oil, rose oil, eucalyptus oil, camphor, peppermint And natural and synthetic fragrances such as oil, spearmint oil, geraniol, mandarin oil, spruce, citronellol and the like.

色素類としては、例えば、タール色素、天然色素等が挙げられる。タール色素としては、例えば、青色1号、青色2号、黄色4号、黄色5号、緑色3号、緑色4号、緑色204号、黄色202号等が挙げられる。天然色素としては、例えば、クロロフィル、リボフラビン、クロシン、アントラキノン、コチニール、カンタキサンチン、紅花色素等が挙げられる。   Examples of the pigments include tar pigments and natural pigments. Examples of the tar pigment include Blue No. 1, Blue No. 2, Yellow No. 4, Yellow No. 5, Green No. 3, Green No. 4, Green No. 204, Yellow No. 202 and the like. Examples of natural pigments include chlorophyll, riboflavin, crocin, anthraquinone, cochineal, canthaxanthin, safflower pigment, and the like.

以下に、実施例に基づいてこの発明をより具体的に説明する。ただし、これらの実施例は如何なる意味においても特許請求の範囲に記載の発明を限定するものではない。   Hereinafter, the present invention will be described more specifically based on examples. However, these examples do not limit the invention described in the claims in any way.

(1)じゃばら乾燥果皮の調製
和歌山県和歌山市松江北のじゃばら果樹からじゃばら果実を10月末頃に採取して、その果皮を手で剥ぎ取った。剥ぎ取った果皮を80℃で32時間熱乾燥して乾燥果皮を得た。乾燥果皮をボールミルで粉砕して、10メッシュの篩に掛け、10メッシュの篩に残留したじゃばら乾燥果皮末を得た。
(1) Preparation of dried rose peels The peeled fruits were collected around the end of October from the roses of Matsue Kita, Wakayama City, Wakayama Prefecture, and the peels were peeled off by hand. The peeled peel was heat-dried at 80 ° C. for 32 hours to obtain a dried peel. The dried fruit skin was pulverized with a ball mill, passed through a 10 mesh sieve, and a loose dried skin powder remaining on the 10 mesh sieve was obtained.

(2)入浴剤の製造
(1)で調製したじゃばら乾燥果皮20gを収納袋に収納して、収納袋の開放部を閉鎖し入浴剤を製造した。なお、収納袋は、ポリエチレン繊維、ポリアミド繊維、ポリプロピレン繊維を含む不織布2枚を接着剤で張り合わせた長方形状のもの(縦:15cm×横:10cm、株式会社ヤマダ薬研)を使用した。
(2) Manufacture of bathing agent 20 g of dried rose peel prepared in (1) was stored in a storage bag, and the opening part of the storage bag was closed to manufacture a bathing agent. In addition, the storage bag used was a rectangular shape (vertical: 15 cm × width: 10 cm, Yamada Yakuken Co., Ltd.) in which two nonwoven fabrics containing polyethylene fiber, polyamide fiber, and polypropylene fiber were bonded together with an adhesive.

(3)入浴剤による抗アレルギー効果
アトピー性皮膚炎及びアレルギー性皮膚炎の患者20人を(2)で製造した入浴剤を入れた風呂に7日間毎日入浴させ、入浴剤の効果を調べた。その結果を表1から表3に示す。
(3) Anti-allergic effect by bathing agent 20 patients with atopic dermatitis and allergic dermatitis were bathed daily in a bath containing the bathing agent produced in (2) for 7 days, and the effect of the bathing agent was examined. The results are shown in Tables 1 to 3.

なお、表1は入浴剤による入浴を続けて1日後の症状の評価を、表2は3日後の症状の評価を、表3は7日後の症状の評価を、それぞれ示している。また、比較のため、別のアトピー性皮膚炎及びアレルギー性皮膚炎の患者20人を(2)で製造した入浴剤を入れていない風呂に7日間毎日入浴させ、その症状を評価した。   Table 1 shows the evaluation of symptoms one day after continuing bathing with a bath agent, Table 2 shows the evaluation of symptoms after 3 days, and Table 3 shows the evaluation of symptoms after 7 days. For comparison, another 20 patients with atopic dermatitis and allergic dermatitis were bathed daily for 7 days in a bath without the bath preparation produced in (2), and their symptoms were evaluated.

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Figure 2015113334
Figure 2015113334

表1から表3の記載から、この発明の入浴剤の使用によって、アトピー性皮膚炎及びアレルギー性皮膚炎の症状が大きく改善したことが分かった。なお、この発明の入浴剤を使用しなかった患者では、改善効果は全く認められなかった。   From the descriptions in Tables 1 to 3, it was found that the symptoms of atopic dermatitis and allergic dermatitis were greatly improved by the use of the bath preparation of the present invention. In patients who did not use the bathing agent of the present invention, no improvement effect was observed.

Claims (5)

じゃばら乾燥果皮と、
じゃばら乾燥果皮を収容し、透水性を有する収容袋と、
を備える入浴剤。
With dry dried peel,
A bag containing dried dry peel and water permeability,
Bath salt with.
じゃばら果皮を熱乾燥法、フリーズドライ法、スプレードライ法の何れかによって乾燥する請求項1に記載の入浴剤。   The bath agent according to claim 1, wherein the peel is dried by any one of a heat drying method, a freeze drying method and a spray drying method. じゃばら果皮をフリーズドライ法によって乾燥したのち、熱乾燥法により乾燥する請求項2に記載の入浴剤。   The bath agent according to claim 2, wherein the peel is dried by a freeze drying method and then dried by a heat drying method. 80℃で熱乾燥する請求項3に記載の入浴剤。   The bath agent according to claim 3, which is thermally dried at 80 ° C. じゃばら乾燥果皮が、果皮末である請求項1から請求項4の何れかに記載の入浴剤。   The bath agent according to any one of claims 1 to 4, wherein the dry dried peel is a peel end.
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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5551015A (en) * 1978-10-10 1980-04-14 Mitsugi Takahashi Bath perfumery made from orange peel
JPS56111131U (en) * 1980-01-30 1981-08-27
JPS58168538U (en) * 1982-04-30 1983-11-10 今村 勝利 Bath salts in a strainer bag
JPH03128315A (en) * 1989-07-01 1991-05-31 Tadao Shiraishi Bathing agent
JPH07179329A (en) * 1993-12-22 1995-07-18 Tsumura & Co Bathing agent composition
JP2007238464A (en) * 2006-03-06 2007-09-20 Nihon Kolmar Co Ltd Cosmetic product
JP2011510980A (en) * 2008-02-01 2011-04-07 イーエルシー マネージメント エルエルシー Topical composition containing Citrus bellows extract
JP2012111743A (en) * 2010-05-27 2012-06-14 Jabara Laboratory:Kk Antiallergic food and drink

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5551015A (en) * 1978-10-10 1980-04-14 Mitsugi Takahashi Bath perfumery made from orange peel
JPS56111131U (en) * 1980-01-30 1981-08-27
JPS58168538U (en) * 1982-04-30 1983-11-10 今村 勝利 Bath salts in a strainer bag
JPH03128315A (en) * 1989-07-01 1991-05-31 Tadao Shiraishi Bathing agent
JPH07179329A (en) * 1993-12-22 1995-07-18 Tsumura & Co Bathing agent composition
JP2007238464A (en) * 2006-03-06 2007-09-20 Nihon Kolmar Co Ltd Cosmetic product
JP2011510980A (en) * 2008-02-01 2011-04-07 イーエルシー マネージメント エルエルシー Topical composition containing Citrus bellows extract
JP2012111743A (en) * 2010-05-27 2012-06-14 Jabara Laboratory:Kk Antiallergic food and drink

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