JP2015078479A - Virus removal method from textile product - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a method which can inactivate viruses sticking to a textile product polluted with vomit without using chlorine-based bleach.SOLUTION: A virus removal method from a textile product, removes viruses sticking to fibers by contacting a process liquid (X) containing a peroxide generating hydrogen peroxide when dissolved in water or hydrogen peroxide, a specific bleach activator and an inorganic alkali agent, to the textile product. Preferably, the textile product contacted with the process liquid (X) is further contacted with a process liquid (Y) containing not less than one compounds chosen from a group consisting of aminocarboxylic acids, amino carboxylates, water-soluble metal salts, and cationic compounds.

Description

  The present invention relates to a virus removal method for textile products.

  In recent years, virus infection has become a problem throughout the year. A virus that could not be completely removed even if it was intended to remove the virus may float in the air and be infected by a virus that remains active. For example, in the case of norovirus or the like, infectious gastroenteritis (such as a mass infection in a hotel) may occur due to secondary infection from vomit.

On the other hand, reports on research on inactivation of viruses such as Norovirus are increasing.
In Patent Document 1, a composition containing one or more quaternary ammonium salts selected from dialkyldimethylammonium salts and alkylbenzyldimethylammonium salts and benzyl alcohol has an inactivating effect on norovirus, Is disclosed.
In Patent Document 2, a composition containing a divalent water-soluble metal salt, a compound having a specific structure (such as methylglycine diacetate or iminodisuccinic acid), and a water-soluble solvent has a virus inactivating effect. Are disclosed.

JP 2013-40167 A International Publication No. 2012/090989

At home, in order to prevent infection with norovirus, it is also effective to remove viruses and inactivate viruses in textile products in addition to hand washing. On the other hand, in the case where a fiber product having a large amount of sputum adhered thereto was washed using the compositions described in Patent Documents 1 and 2 above, the inactivation effect on the virus adhered to the fiber might not be sufficient. .
The Ministry of Health, Labor and Welfare recommends the use of sodium hypochlorite (chlorine bleach) when treating textile products contaminated with sputum. However, when treating textile products contaminated with acidic sputum containing a large amount of organic components with chemicals, the amount of chemicals used increases, so the use of chlorine bleaches with generation of chlorine gas is preferred. Absent. In addition, chlorine bleach is not suitable for use in clothes with colored patterns.
This invention is made | formed in view of the said situation, and makes the subject the method which can inactivate the virus adhering to the textiles contaminated with the sputum without using a chlorine bleach.

As a result of investigations, the present inventors have found that norovirus can be removed without damaging the textile by adopting a specific treatment liquid when the textile is contaminated with sputum, and the present invention has been completed. .
That is, the virus removal method for a textile product of the present invention comprises a peroxide or hydrogen peroxide that dissolves in water to generate hydrogen peroxide, a compound represented by the following general formula (I), and a general formula (II The treatment liquid (X) containing one or more compounds selected from the group consisting of the compounds represented by) and an inorganic alkaline agent is brought into contact with the fiber product to remove the virus attached to the fiber. Features.

［式中、Ｒ^１０及びＲ^２０は、それぞれ独立して炭素数７〜１３のアルキル基又はアルケニル基である。Ｍ^１及びＭ^２は、それぞれ独立して水素原子又は塩形成カチオンである。］

[Wherein, R ¹⁰ and R ²⁰ each independently represents an alkyl group or an alkenyl group having 7 to 13 carbon atoms. M ¹ and M ² are each independently a hydrogen atom or a salt-forming cation. ]

  In the virus removal method for a textile product according to the present invention, the textile product brought into contact with the treatment liquid (X) has at least one compound selected from the group consisting of an aminocarboxylic acid, an aminocarboxylic acid salt, and a water-soluble metal salt. It is preferable to further contact the treatment liquid (Y) containing the cationic compound.

  According to the virus removal method for a textile product of the present invention, it is possible to inactivate a virus attached to a textile product contaminated with vomit without using a chlorine bleach.

  In the present specification, “virus inactivation” refers to reducing the number of infectious viruses (infectivity titer) attached to an object.

  The virus removal method for a textile product of the present invention is represented by a peroxide or hydrogen peroxide that dissolves in water to generate hydrogen peroxide, a compound represented by general formula (I), and general formula (II). A treatment step (hereinafter referred to as “first treatment step”) in which a treatment liquid (X) containing at least one compound selected from the group consisting of the following compounds and an inorganic alkaline agent is brought into contact with the textile product. ).

Examples of textile products that are subject to such virus removal methods include Y-shirts, T-shirts, polo shirts, blouses, chinos, suits, slacks, skirts, tablecloths, place mats, curtains, pillowcases, sofas, sheets, and toilet mats. Etc.
The material of the fiber product is not particularly limited. For example, natural fibers such as cotton, wool and hemp; synthetic fibers such as polyester, nylon and acrylic; semi-synthetic fibers such as acetate; rayon, tencel, polynosic and the like Recycled fibers of these, or blended products, blended fabrics or blended products of these various fibers can be mentioned.
The present invention is a virus removal method useful for treating a fiber product to which a virus is attached, for example, a virus removal method useful for treating a fiber product contaminated with vomit, excrement and the like. Among these, it is a virus removal method particularly useful for treating textile products contaminated with acidic sputum containing a large amount of organic components.

<First treatment process>
In the first treatment step, the treatment liquid (X) is brought into contact with the textile product. By using the treatment liquid (X), a practically sufficient virus inactivating effect can be obtained for viruses attached to the fibers. Then, by bringing the treatment liquid (X) into contact with the textile product, the virus can be inactivated without using a chlorine bleaching agent even in the textile product contaminated with the sputum.

(Processing liquid (X))
The treatment liquid (X) comprises a peroxide or hydrogen peroxide (hereinafter also referred to as “component (a)”) that dissolves in water to generate hydrogen peroxide, a compound represented by the general formula (I), Contains one or more compounds selected from the group consisting of compounds represented by formula (II) (hereinafter also referred to as “component (b)”) and an inorganic alkali agent (hereinafter also referred to as “component (c)”). Liquid.
In the treatment liquid (X), the total content of the component (a), the component (b), and the component (c) is preferably 0.1% by mass or more based on the total mass of the treatment liquid (X). .13 to 1% by mass is more preferable, and 0.15 to 0.9% by mass is more preferable. If the total content is equal to or greater than the preferable lower limit, a virus removal effect is more easily obtained. On the other hand, if it is below a preferable upper limit value, it is hard to damage a textile product.

・ Peroxide or hydrogen peroxide that dissolves in water to generate hydrogen peroxide: Component (a) (a) Component includes sodium percarbonate, sodium perborate, sodium perborate, trihydrate, etc. A peroxide of hydrogen peroxide. Of these, sodium percarbonate and hydrogen peroxide are preferred from the viewpoint of solubility during use.
(A) component contained in processing liquid (X) may be used individually by 1 type, and may use 2 or more types together.
In the treatment liquid (X), the content ratio of the component (a) in the total of the components (a), (b) and (c) is preferably 1% by mass or more, more preferably 1 to 90% by mass. More preferably, it is 5 to 80% by mass, particularly preferably 10 to 40% by mass. When the content of the component (a) is less than the preferable lower limit, a sufficient virus removal effect may not be obtained.

When sodium percarbonate is used as the component (a), in order to improve stability over time, an aqueous boric acid solution and an alkali metal silicate aqueous solution may be used by spraying (see Japanese Patent No. 2918991) or non-hazardous. For this purpose, it is preferable to use coated sodium percarbonate granulated with various inorganic substances.
The coated sodium percarbonate can be produced by a known method, and can also be obtained from a commercial product. For example, coated sodium percarbonate coated with boric acid can be produced by the method described in JP-A-59-196399.
The average particle size of the coated sodium percarbonate is preferably 200 to 1000 μm, more preferably 300 to 800 μm. In order to satisfy both solubility and stability, the total of the particles having a particle diameter of 125 μm or less and the particles having a particle diameter of 1000 μm or more is preferably 10% by mass or less of the entire particles. Here, the average particle diameter is a mass-based median diameter obtained by a measurement method using a classification operation described later.

Measuring method of average particle size:
First, the measurement object (sample) is classified using a 9-stage sieve having a mesh opening of 1680 μm, 1410 μm, 1190 μm, 1000 μm, 710 μm, 500 μm, 350 μm, 250 μm, and 149 μm and a tray. In the classification operation, the 9-stage sieve is stacked on the upper side of the tray so that the opening is gradually increased upward, and 100 g / time of the sample is put on the top sieve having the opening of 1680 μm.
Next, the lid is put on and attached to a low-tap type sieve shaker (manufactured by Iida Seisakusho, tapping: 156 times / minute, rolling: 290 times / minute), and is vibrated for 10 minutes. Then, each sieve and the sample which remained on the saucer are each collect | recovered and the mass of a sample is measured.
Then, the mass frequency of the tray and each sieve is integrated, the opening of the first sieve where the integrated mass frequency is 50% or more is a μm, the opening of the sieve that is one step larger than a μm is b μm, The average particle size (50% by mass particle size) is obtained from the following equation, where c is the total mass frequency from the screen to the aμm sieve, and d% is the mass frequency on the aμm sieve. The diameter.

-One or more compounds selected from the group consisting of the compound represented by the following general formula (I) and the compound represented by the general formula (II): (b) component (b) component is a bleach activator. It is an organic peracid precursor that reacts with hydrogen peroxide to generate an organic peracid.

［式中、Ｒ^１０及びＲ^２０は、それぞれ独立して炭素数７〜１３のアルキル基又はアルケニル基である。Ｍ^１及びＭ^２は、それぞれ独立して水素原子又は塩形成カチオンである。］

[Wherein, R ¹⁰ and R ²⁰ each independently represents an alkyl group or an alkenyl group having 7 to 13 carbon atoms. M ¹ and M ² are each independently a hydrogen atom or a salt-forming cation. ]

In the formulas (I) and (II), R ¹⁰ and R ²⁰ each have 7 to 13 carbon atoms, preferably 7 to 11 carbon atoms, and more preferably 9 to 11 carbon atoms. is there.
The alkyl group and alkenyl group in R ¹⁰ and R ²⁰ may each be linear or branched.
The salt-forming cations in M ¹ and M ² are cations that electrically neutralize —SO ₃ ^— and —COO ^— such as alkali metal (sodium, potassium, etc.) ions, ammonium ions, amines (monoethanol). And cations of alkanolamines such as amine, diethanolamine, and triethanolamine).

  Examples of the compound represented by the formula (I) (hereinafter also referred to as “compound (I)”) include sodium octanoyloxybenzenesulfonate, sodium nonanoyloxybenzenesulfonate, sodium decanoyloxybenzenesulfonate, undeca Examples include sodium noyloxybenzenesulfonate, sodium dodecanoyloxybenzenesulfonate, and the like. Among these, sodium nonanoyloxybenzenesulfonate, sodium decanoyloxybenzenesulfonate, and sodium dodecanoyloxybenzenesulfonate are preferable.

  Examples of the compound represented by the formula (II) (hereinafter also referred to as “compound (II)”) include octanoyloxybenzoic acid, nonanoyloxybenzoic acid, decanoyloxybenzoic acid, undecanoyloxybenzoic acid, and dodecanoyloxy. Benzoic acid; octanoyloxybenzene, nonanoyloxybenzene, decanoyloxybenzene, undecanoyloxybenzene, dodecanoyloxybenzene and the like. Of these, decanoyloxybenzoic acid is preferred.

(B) component contained in processing liquid (X) may be used individually by 1 type, and may use 2 or more types together.
Of these, the compound (I) is preferably used as the component (b).
In addition, as the component (b), from the group consisting of sodium 4-dodecanoyloxybenzenesulfonate, sodium 4-nonanoyloxybenzenesulfonate, sodium 4-decanoyloxybenzenesulfonate and 4-decanoyloxybenzoic acid At least one selected is preferable, and sodium 4-dodecanoyloxybenzenesulfonate is particularly preferable.
In the treatment liquid (X), the content ratio of the component (b) in the total of the components (a), (b) and (c) is preferably 0.05 to 10% by mass, more preferably 0. It is 4-5 mass%, More preferably, it is 1-5 mass%. When the content of the component (b) is less than the preferable lower limit, it is difficult to obtain a sufficient virus removal effect. Even if the content of the component (b) exceeds the preferable upper limit, the virus removal effect is not further increased, which is uneconomical.

In the treatment liquid (X), the mixing ratio of the component (a) and the component (b) is preferably 1/5 to 50/1 in terms of a mass ratio represented by the component (a) / component (b). 5-10 / 1 is more preferable.
When the mass ratio represented by (a) component / (b) component is within the above preferred range, the virus inactivation effect is further improved.

-Inorganic alkaline agent: (c) component (c) component increases the pH of the treatment liquid (X), thereby inactivating the virus adhering to the fiber when the fiber product is contaminated with acidic sputum. Formulated for the purpose of enhancing.
(C) As a component, a well-known thing can be used and carbonate and a silicate are preferable.
Specific examples of the carbonate include sodium carbonate, potassium carbonate, sodium potassium carbonate, sodium bicarbonate, and sesquicarbonate.
Specific examples of the silicate include sodium silicate, crystalline layered sodium silicate, and amorphous sodium silicate.
(C) component contained in processing liquid (X) may be used individually by 1 type, and may use 2 or more types together.
Among these, the component (c) is preferably at least one selected from the group consisting of sodium carbonate, potassium carbonate, crystalline layered sodium silicate and amorphous sodium silicate, and sodium carbonate is particularly preferred.
In the treatment liquid (X), the content ratio of the component (c) in the total of the components (a), (b) and (c) is preferably 3 to 80% by mass, more preferably 5 to 70% by mass. %, More preferably 10 to 60% by mass. When the content of the component (c) is less than the preferable lower limit, the virus removal effect tends to be lowered. On the other hand, when the content of the component (c) exceeds the preferable upper limit, the pH of the treatment liquid (X) may be too high.
As the component (c), a polymer compound (such as an acrylic acid-maleic anhydride copolymer or a salt thereof) or a fatty acid (such as lauric acid) may be used.

In the treatment liquid (X), the mixing ratio of the component (a) and the component (c) is preferably 1/100 to 4/1 in terms of mass ratio represented by the component (a) / component (c). 5 to 4/1 is more preferable, and 1/2 to 1/1 is more preferable.
If the mass ratio represented by (a) component / (c) component is within the above preferred range, the virus inactivation effect is further improved.

-Solvent The treatment liquid (X) preferably uses water as a solvent from the viewpoint of ease of preparation, solubility in water when used, and the like.
The water to be used is preferably ion-exchanged water or distilled water excluding metal ions such as heavy metals dissolved in water from the viewpoint of the temporal stability of the treatment liquid (X).
In the treatment liquid (X), the content ratio of water is preferably 50% by mass or more, more preferably 70% by mass or more, and further preferably 90% by mass or more with respect to the total mass of the treatment liquid (X).
When the water content is at least the preferred lower limit, the liquid stability of the treatment liquid (X) with time will be better.

As the solvent, in addition to water, a water-soluble solvent may be used. The “water-soluble solvent” as used herein refers to an organic solvent that is mixed with water at an arbitrary ratio to be mixed transparently.
Examples of the water-soluble solvent include primary alcohols having 2 to 3 carbon atoms such as ethanol and 2-isopropanol; glycols having 2 to 6 carbon atoms such as ethylene glycol, propylene glycol and dipropylene glycol; glycerin and diethylene glycol monobutyl ether. And a polyhydric alcohol having 3 to 8 carbon atoms. Among these, ethanol, glycerin, and diethylene glycol monobutyl ether are preferable, and ethanol is particularly preferable. It is also preferable to use a mixed solvent of ethanol and other water-soluble solvent.
As ethanol, 10% desodium benzoate / alcohol solution, or “description of denatured alcohol under the Alcohol Business Act” such as octaacetylated sucrose or brucine (Guideline for using alcohol (10th edition) [Division 2 ] Alcohol use permission application manual (August 2012 Ministry of Economy, Trade and Industry) It is preferable to use ethanol containing a small amount of denaturing agent.
A water-soluble solvent may be used individually by 1 type, and may use 2 or more types together.
When using a water-soluble solvent, 3-30 mass% is preferable with respect to the total mass of the processing liquid (X), and, as for the content rate of the water-soluble solvent in processing liquid (X), More preferably, it is 5-20 mass%. Yes, more preferably 7 to 15% by mass. If the content rate of a water-soluble solvent is the said preferable range, solubility and liquid stability will improve more.

-Other components Treatment liquid (X) may contain other components other than (a) component, (b) component, and (c) component.
Examples of such other components include components that can be used in conventionally known clothing detergents, such as surfactants, detergency builders, fluorescent brighteners, enzymes, enzyme stabilizers, polymers, anti-caking agents, antifoaming agents, Examples thereof include a reducing agent, a metal ion scavenger, a pH adjuster, a fragrance, and a dye.

.. Surfactant The treatment liquid (X) may contain a surfactant such as an anionic surfactant, a nonionic surfactant, a cationic surfactant, and an amphoteric surfactant. In the treatment liquid (X), the content of the surfactant in the total of the components (a), (b), (c) and other components (including the surfactant) is 10 to 30% by mass. Preferably, 15 to 30% by mass is more preferable.

... Anionic surfactant Examples of the anionic surfactant include the following.
(1) Methyl ester, ethyl ester or propyl ester (α-SF or MES) salt of α-sulfo fatty acid. The kind of the α-sulfo fatty acid alkyl ester salt is not particularly limited, and any of the α-sulfo fatty acid alkyl ester salts used in general granular detergents can be suitably used. Examples of suitable α-sulfo fatty acid alkyl ester salts are shown below.

［式中、Ｒ^０１は、炭素数８〜２０の直鎖状もしくは分岐鎖状のアルキル基又はアルケニル基である。Ｒ^０２は、炭素数１〜６の直鎖状もしくは分岐鎖状のアルキル基である。Ｍは、塩形成カチオンである。］

[Wherein, R ⁰¹ represents a linear or branched alkyl group or alkenyl group having 8 to 20 carbon atoms. R ⁰² is a linear or branched alkyl group having 1 to 6 carbon atoms. M is a salt-forming cation. ]

In the above formula, R ⁰¹ is a linear or branched alkyl group having 8 to 20 carbon atoms or a linear or branched alkenyl group having 8 to 20 carbon atoms. R ⁰¹ has 8 to 20 carbon atoms, preferably 10 to 18 carbon atoms, and more preferably 14 to 16 carbon atoms.
In the above formula, R ⁰² is a linear alkyl group having 1 to 6 carbon atoms or a branched alkyl group having 1 to 6 carbon atoms. The number of carbon atoms of R ⁰² is 1 to 6, preferably 1 to 3. Specific examples include a methyl group, an ethyl group, a propyl group, and an isopropyl group, and since the detergency is further improved, a methyl group, an ethyl group, and a propyl group are preferable, and a methyl group is particularly preferable.
In the above formula, M is a salt-forming cation and is a cation that electrically neutralizes —SO ₃ ^— . Examples of M include alkali metal (sodium, potassium, etc.) ions, ammonium ions, cations of amines (monoethanolamine, diethanolamine, triethanolamine, etc.), and alkali metal ions are preferred.

(2) Alkali metal salts or alkaline earth metal salts of higher fatty acids having an average number of carbon atoms of 10 to 20 fatty acids.
(3) A linear or branched alkylbenzene sulfonate (LAS or ABS) salt having an alkyl group having 8 to 18 carbon atoms.
(4) Alkane sulfonate having 10 to 20 carbon atoms.
(5) α-olefin sulfonate (AOS) having 10 to 20 carbon atoms.
(6) C10-20 alkyl sulfate or alkenyl sulfate (AS).
(7) Any of alkylene oxides having 2 to 4 carbon atoms, or ethylene oxide (EO) and propylene oxide (PO) (molar ratio EO / PO = 0.1 / 9.9 to 9.9 / 0.1) An alkyl (or alkenyl) ether sulfate (AES) having a linear or branched alkyl (or alkenyl) group having 10 to 20 carbon atoms added with an average of 0.5 to 10 mol.
(8) Any of alkylene oxides having 2 to 4 carbon atoms, or ethylene oxide and propylene oxide (molar ratio EO / PO = 0.1 / 9.9 to 9.9 / 0.1), average 3 to 30 mol An alkyl (or alkenyl) phenyl ether sulfate having an added linear or branched alkyl (or alkenyl) group having 10 to 20 carbon atoms.
(9) Any one of alkylene oxides having 2 to 4 carbon atoms, or ethylene oxide and propylene oxide (molar ratio EO / PO = 0.1 / 9.9 to 9.9 / 0.1), an average of 0.5 to An alkyl (or alkenyl) ether carboxylate having a linear or branched alkyl (or alkenyl) group having 10 to 20 carbon atoms added with 10 moles.
(10) Alkyl polyhydric alcohol ether sulfates such as C10-20 alkyl glyceryl ether sulfonates.
(11) Long chain monoalkyl, dialkyl or sesquialkyl phosphate.
(12) Polyoxyethylene monoalkyl, dialkyl or sesquialkyl phosphate.
Among the above examples, preferable anionic surfactants include α-sulfo fatty acid alkyl ester salt (MES), alkali metal salt of linear alkylbenzene sulfonic acid (LAS) (for example, sodium salt or potassium salt), AOS, AES. Alkali metal salts (for example, sodium salt or potassium salt), and alkali metal salts of higher fatty acids (for example, sodium salt or potassium salt). Among these, MES having an alkyl group having 14 to 16 carbon atoms, an LAS salt having an alkyl group having 10 to 14 carbon atoms, and a higher fatty acid salt having 10 to 20 carbon atoms are particularly preferable.
These anionic surfactants can be used singly or in appropriate combination of two or more.

... Nonionic surfactant Examples of the nonionic surfactant include the following.
(1) Polyoxyalkylene alkyl (or alkenyl) obtained by adding an average of 3 to 30 moles, preferably 5 to 20 moles of an alkylene oxide having 2 to 4 carbon atoms to an aliphatic alcohol having 6 to 22 carbon atoms, preferably 8 to 18 carbon atoms )ether.
Among these, polyoxyethylene alkyl (or alkenyl) ether and polyoxyethylene polyoxypropylene alkyl (or alkenyl) ether are preferable. Examples of the aliphatic alcohol used here include primary alcohols and secondary alcohols. The alkyl group may have a branched chain. As the aliphatic alcohol, a primary alcohol is preferable.
(2) Polyoxyethylene alkyl (or alkenyl) phenyl ether.
(3) Fatty acid alkyl ester alkoxylate represented by the following general formula, for example, having an alkylene oxide added between the ester bonds of the long-chain fatty acid alkyl ester.
R ⁰³ CO (OR ⁰⁵ ) _n OR ⁰⁴
[Wherein R ⁰³ CO represents a fatty acid residue having 5 to 21 carbon atoms, preferably 7 to 17 carbon atoms. OR ⁰⁵ represents an oxyalkylene group having 2 to 4 carbon atoms, preferably 2 or 3, such as an oxyethylene group or an oxypropylene group. n shows the average repeating number of an oxyalkylene group, and is 3-30, Preferably it is the number of 5-20. R ⁰⁴ represents an alkyl group which may have a substituent having 1 to 3 carbon atoms. ]
(4) Polyoxyethylene sorbitan fatty acid ester.
(5) Polyoxyethylene sorbite fatty acid ester.
(6) Polyoxyethylene fatty acid ester.
(7) Polyoxyethylene hydrogenated castor oil.
(8) Glycerin fatty acid ester.
Among the above examples, the preferred nonionic surfactant is preferably the nonionic surfactant (1). Among these, a polyoxyalkylene alkyl (or alkenyl) ether obtained by adding an average of 5 to 20 moles of an alkylene oxide having 2 to 4 carbon atoms to an aliphatic alcohol having 12 to 16 carbon atoms is preferable. A polyoxyethylene alkyl (or alkenyl) ether having a melting point of 50 ° C. or lower and an HLB of 9 to 16, a polyoxyethylene polyoxypropylene alkyl (or alkenyl) ether, a fatty acid methyl ester ethoxylate obtained by adding ethylene oxide to a fatty acid methyl ester, Fatty acid methyl ester ethoxypropoxylate obtained by adding ethylene oxide and propylene oxide to fatty acid methyl ester is particularly preferred. These nonionic surfactants can be used individually by 1 type or in combination of 2 or more types as appropriate.
The HLB of the nonionic surfactant is a value obtained by the Griffin method (Yoshida, Shindo, Ogaki, Yamanaka, edited by “New Edition Surfactant Handbook”, Kogyoshosho, 1991, No. 234). Page). The melting point is a value measured by a melting point measurement method described in JIS K0064-1992 “Method for measuring melting point and melting range of chemical product”.

... Cationic surfactant Examples of the cationic surfactant include those shown below.
(1) Dilong chain alkyl dishort chain alkyl type quaternary ammonium salt.
(2) Mono long chain alkyl tri short chain alkyl type quaternary ammonium salt.
(3) Tri long chain alkyl mono short chain alkyl type quaternary ammonium salt.
However, the above “long-chain alkyl” represents an alkyl group having 12 to 26 carbon atoms, preferably 14 to 18 carbon atoms.
“Short-chain alkyl” refers to an alkyl group that includes a substituent such as a phenyl group, a benzyl group, a hydroxy group, or a hydroxyalkyl group, and may have an ether bond between carbons. Among them, an alkyl group having 1 to 4 carbon atoms, preferably 1 to 2 carbon atoms; a benzyl group; a hydroxyalkyl group having 2 to 4 carbon atoms, preferably 2 to 3 carbon atoms; a polyalkyl having 2 to 4 carbon atoms, preferably 2 to 3 carbon atoms. Oxyalkylene groups are preferred.

... Amphoteric surfactants Examples of amphoteric surfactants include imidazoline-based amphoteric surfactants and amide betaine-based amphoteric surfactants. Specifically, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine and lauric acid amidopropyl betaine are preferable.

-Detergency builders Detergency builders include inorganic builders and organic builders.
Examples of the inorganic builder include alkali metal sulfates such as sodium sulfate and potassium sulfate; alkali metal chlorides such as sodium chloride and potassium chloride; crystalline aluminosilicates and amorphous aluminosilicates.
Among these, [1] a water content at 20 ° C. of 10 to 30% by mass, [2] SiO ₂ / Al ₂ O ₃ = 1 to 2, and [3] a primary particle size of 3. It is a synthetic aluminosilicate of 0 μm or less, and in particular, synthetic zeolite having an average primary particle size of 0.5 to 3 μm is preferable from the viewpoint of performance and manufacturability.
Zeolite may be used as powder, zeolite slurry, and zeolite agglomerated dry particles obtained by drying the slurry. Specific examples include “Silton B” (manufactured by Mizusawa Chemical Co., Ltd.), “Toyo Builder” (manufactured by Tosoh Corporation), and the like. Moreover, it is preferable that the value of the oil absorptivity by a JIS K 5101 method of a synthetic aluminosilicate is 40-50 mL / 100g.
Examples of the organic builder include aminocarboxylates such as nitrilotriacetate, ethylenediaminetetraacetate, β-alanine diacetate, aspartate diacetate, methylglycine diacetate, and iminodisuccinate; serine diacetate, hydroxyiminodia Hydroxyaminocarboxylates such as succinate, hydroxyethylethylenediamine triacetate, dihydroxyethylglycine; Hydroxycarboxylates such as hydroxyacetate, tartrate, citrate, gluconate; pyromellitic acid salt, benzoate Cyclocarboxylates such as polycarboxylates and cyclopentanetetracarboxylates; ether carboxylates such as carboxymethyltaltronate, carboxymethyloxysuccinate, oxydisuccinate, tartaric acid mono- or disuccinate; poly Crylate, acrylic acid-allyl alcohol copolymer salt, acrylic acid-maleic acid copolymer salt, polyacetal carboxylic acid salt such as polyglyoxylic acid; hydroxyacrylic acid polymer, polysaccharide-acrylic acid copolymer Salt of acrylic acid polymer or copolymer such as polymer; salt of polymer or copolymer such as maleic acid, itaconic acid, fumaric acid, tetramethylene 1,2-dicarboxylic acid, succinic acid, aspartic acid; starch, And polysaccharide derivatives such as polysaccharide oxides such as cellulose, amylose and pectin.
Among the above-mentioned organic builder, citrate, aminocarboxylate, hydroxyaminocarboxylate, polyacrylate, acrylic acid-maleic acid copolymer salt, and polyacetal carboxylic acid salt are preferable. In particular, hydroxyiminodisuccinate, salt of acrylic acid-maleic acid copolymer having a weight average molecular weight of 1000 to 80000, polyacrylate, polyglyoxyl having a weight average molecular weight of 800 to 1000000 (preferably 5000 to 200000) Polyacetal carboxylates such as acids (for example, those described in JP-A No. 54-52196) are preferred.
A detergency builder can be used alone or in combination of two or more.
For the purpose of improving the detergency and stain dispersibility in the washing liquid, it is preferable to use an organic builder such as polyacrylate and acrylic acid-maleic acid copolymer salt and an inorganic builder such as zeolite. .

..Fluorescent whitening agent Examples of fluorescent whitening agents include 4,4′-bis- (2-sulfostyryl) -biphenyl salt, 4,4′-bis- (4-chloro-3-sulfostyryl) -biphenyl Examples thereof include salts, 2- (styrylphenyl) naphthothiazole derivatives, 4,4′-bis (triazol-2-yl) stilbene derivatives, and bis- (triazinylaminostilbene) disulfonic acid derivatives.
Examples of commercially available fluorescent whitening agents include Whiteex SA, Whitetex SKC (above, trade name; manufactured by Sumitomo Chemical Co., Ltd.), Chino Pearl AMS-GX, Chino Pearl DBS-X, Chino Pearl CBS-X (above, trade name; Ciba Specialty Chemicals), Lemonite CBUS-3B (trade name; manufactured by Khyati Chemicals), and the like. Of these, Tinopearl CBS-X and Tinopearl AMS-GX are preferred.
A fluorescent brightening agent can be used alone or in combination of two or more.

.. Enzymes Enzymes that can be blended in the treatment liquid (X) include hydrolases, oxidoreductases, lyases, transferases, and isomerases when classified from the reactivity of the enzymes. Of these, protease, esterase, lipase, nuclease, cellulase, amylase, pectinase and the like are preferable.
Examples of the protease include pepsin, trypsin, chymotrypsin, collagenase, keratinase, elastase, sptilisin, papain, promerin, carboxypeptidase A or B, aminopeptidase, aspergillopeptidase A or B, and the like. As commercial products of protease, sabinase, alcalase, cannase, everase, deozyme (above, trade name: manufactured by Novozymes); API21 (trade name: manufactured by Showa Denko KK); Maxacar, Maxapem (above, trade name: Genencor) Protease K-14 or K-16 (protease described in JP-A-5-25492) and the like.
Examples of esterases include gastric lipase, bunkreatic lipase, plant lipase, phospholipase, cholinesterase, phosphotase and the like.
Examples of the lipase include lipolase, lipex (trade name; manufactured by Novozymes), liposome (trade name; manufactured by Showa Denko KK), and the like.
As cellulase, cellzyme (trade name; manufactured by Novozymes); alkaline cellulase K, alkaline cellulase K-344, alkaline cellulase K-534, alkaline cellulase K-539, alkaline cellulase K-577, alkaline cellulase K-425, alkaline cellulase K-521, alkaline cellulase K-580, alkaline cellulase K-588, alkaline cellulase K-597, alkaline cellulase K-522, CMCase I, CMCase II, alkaline cellulase E-II, alkaline cellulase E-III (or more, Cellulase described in JP-A-63-264699) and the like.
Examples of the amylase include commercially available stainzymes, termamyls, duramils (above, trade names: manufactured by Novozymes) and the like.
An enzyme can be used individually by 1 type or in combination of 2 or more types as appropriate.
In addition, it is preferable to use the enzyme granulated as separate stable particles in a state of being dry blended with detergent dough (particles).

..Enzyme stabilizer Examples of the enzyme stabilizer include calcium salts, magnesium salts, polyols, formic acid, boron compounds and the like. Of these, sodium tetraborate, calcium chloride and the like are preferable.
An enzyme stabilizer can be used individually by 1 type or in combination of 2 or more types as appropriate.

.. Polymers The treatment liquid (X) has an average molecular weight as a binder or powder physical agent when densifying the surfactant-containing particles, and as a component that imparts an anti-recontamination effect on hydrophobic fine particles. A polyethylene glycol having a molecular weight of 200 to 200,000, a polymer of acrylic acid and / or maleic acid having a weight average molecular weight of 1,000 to 100,000, a cellulose derivative such as polyvinyl alcohol, carboxymethyl cellulose, and the like can be blended.
Further, as a soil release agent, a copolymer or terpolymer of terephthalic acid and ethylene glycol and / or propylene glycol units can be blended.
Further, polyvinyl pyrrolidone or the like can be blended in order to impart an effect of preventing color transfer.
Among the above, polyethylene glycol having an average molecular weight of 1500 to 7000 is preferable.
These polymers can be used singly or in appropriate combination of two or more.

-Anti-caking agent Examples of the anti-caking agent include p-toluenesulfonate, xylenesulfonate, acetate, sulfosuccinate, talc, fine powder silica, clay, magnesium oxide and the like. An anti-caking agent can be used singly or in appropriate combination of two or more.

.. Antifoaming agent Examples of antifoaming agents include conventionally known antifoaming agents such as silicone-based / silica-based materials.
An antifoaming agent is good also as an antifoaming agent granulated material manufactured using the method of the 4th page lower left column of Unexamined-Japanese-Patent No. 3-186307. Specifically, first, 100 g of maltodextrin (enzyme-modified dextrin) manufactured by Nissho Chemical Co., Ltd. was added and mixed with 20 g of silicone (compound type, PS antifoam) manufactured by Dow Corning as a defoaming component. A mixture is obtained. Next, 50% by mass of the obtained homogeneous mixture, 25% by mass of polyethylene glycol (PEG-6000, melting point 58 ° C.) and 25% by mass of neutral anhydrous sodium sulfate at 70 to 80 ° C. were then mixed. Granulation by an extrusion granulator (model EXKS-1).
An antifoamer can be used individually by 1 type or in combination of 2 or more types as appropriate.

.. Reducing agent Examples of the reducing agent include sodium sulfite and potassium sulfite.

..Metal ion scavenger The metal ion scavenger captures trace metal ions in tap water and has an effect of suppressing adsorption of metal ions to fibers (objects to be cleaned).
Examples of metal ion scavengers include aminopolyacetic acids such as ethylenediaminetetraacetic acid, nitrilotriacetic acid, and glycolethylenediaminehexaacetic acid; 1-hydroxyethane-1,1-diphosphonic acid (HEDP-H), ethane-1,1-diphosphonic acid Ethane-1,1,2-triphosphonic acid, hydroxyethane-1,1,2-triphosphonic acid, ethane-1,2-dicarboxy-1,2-diphosphonic acid, hydroxymethanephosphonic acid, ethylenediaminetetra (methylenephosphone) Acid), nitrilotri (methylenephosphonic acid), 2-hydroxyethyliminodi (methylenephosphonic acid), hexamethylenediaminetetra (methylenephosphonic acid), diethylenetriaminepenta (methylenephosphonic acid) and other organic phosphonic acid derivatives or salts thereof; Glycolic acid, tartaric acid, Oxalic acid, organic acids such as gluconic acid, or salts thereof, and the like.
A metal ion scavenger can be used individually by 1 type or in combination of 2 or more types as appropriate.

-Fragrance A fragrance is a mixture (fragrance composition) containing a fragrance component, a solvent, a fragrance stabilizer, and the like.
Such perfumes are described in, for example, “Perfume Chemistry (edited by the Chemical Society of Japan, written by Ryoichi Akahoshi, issued on September 16, 1983)”, “Synthetic Perfume Chemistry and Product Knowledge, published by Chemical Industry Daily, 1996”. Are listed. Specific examples of the fragrances include those described in JP-A No. 2002-146399, those described in JP-A No. 2003-89800, and fragrances A to C described in Table 5 of JP-A No. 2007-32270. Perfume compositions A, B and the like described in Table 13 of Kai 2009-155739 can be used.
When adding a fragrance | flavor to both processing liquid (X) and the below-mentioned processing liquid (Y), it is preferable to use the same fragrance | flavor.

・ ・ Dye As the dye, either dye or pigment can be used. From the viewpoint of storage stability, pigments are preferred, and compounds having oxidation resistance such as oxides are particularly preferred. Such compounds include titanium oxide, iron oxide, copper phthalocyanine, cobalt phthalocyanine, ultramarine, bitumen, cyanine blue, cyanine green and the like.
A pigment | dye can be used individually by 1 type or in combination of 2 or more types as appropriate.

..PH adjuster The pH of the treatment liquid (X) can be adjusted with an inorganic alkaline agent (component (c)), but in addition to the component (c), alkanolamines such as monoethanolamine, diethanolamine, triethanolamine; water Sodium oxide, potassium hydroxide, or the like can be used as a pH adjuster.
Moreover, in order to prevent that pH of process liquid (X) becomes high too much, an acid can also be used. Examples of such acids include the metal ion scavengers, alkali metal dihydrogen phosphates such as potassium dihydrogen phosphate, lactic acid, succinic acid, malic acid, gluconic acid, or polycarboxylic acids thereof; sodium bicarbonate, sulfuric acid, Examples include hydrochloric acid.
A pH adjuster can be used individually by 1 type or in combination of 2 or more types as appropriate.

The pH of the treatment liquid (X) is preferably 8 or more, and more preferably 9-11.
When the pH of the treatment liquid (X) is equal to or higher than the preferred lower limit, the inactivation effect on the virus attached to the fibers when the textile product is contaminated with acidic sputum is further increased. On the other hand, when the pH of the treatment liquid (X) exceeds a preferable upper limit value, it is not preferable from the viewpoint of safety when hand washing is assumed.
In the present invention, the pH of the treatment liquid (X) and the treatment liquid (Y) described later is measured using a pH meter (pH meter: model number MP230, manufactured by Mettler Toledo) at 25 ° C. Indicates the value of.

The viscosity of the treatment liquid (X) is preferably 10 mPa · s or less. When the viscosity of the treatment liquid (X) is equal to or less than the preferable upper limit value, the treatment liquid (X) is easily brought into contact with the entire fiber product.
In the present invention, the viscosities of the treatment liquid (X) and the treatment liquid (Y) described below are values when the stock solution is measured at 25 ° C. using a B-type viscometer (manufactured by Tokimec).

-Preparation method of processing liquid (X) It does not specifically limit as a preparation method of processing liquid (X), For example, (a) component, (b) component, and (c) component are dissolved or disperse | distributed to a solvent. Method: A method of dissolving or dispersing a detergent for clothes (powder detergent, liquid detergent, tablet, sheet type, etc.) containing the component (a), the component (b), and the component (c) in a solvent. .
What is necessary is just to manufacture the said detergent for clothing by a conventional method, for example, as a surfactant containing particle group containing (a)-(c) component, or (a) component, (b) component, and (c). It can be prepared as a mixture of components and surfactant-containing particles.

(Method of bringing the treatment liquid (X) into contact with the textile product)
The method of bringing the treatment liquid (X) into contact with the textile product can be appropriately selected depending on the use situation, and the method of immersing the textile product in the treatment liquid (X), spraying, dripping or applying the treatment liquid (X) to the textile product. The method etc. are mentioned. For example, in the former case, a plurality of clothes can be treated together; in the latter case, the treatment is simple, and the treatment liquid (X) is brought into contact mainly with the site contaminated with the vomit and its vicinity. Can do.
Further, in the first treatment step, the treatment for bringing the treatment liquid (X) into contact with the textile product may be repeated using these contact methods.

-Method of immersing the textile product in the treatment liquid (X) As a method of immersing the textile product in the treatment liquid (X) (hereinafter also referred to as "immersion method"), the textile product is directly immersed in the treatment liquid (X). And a method of washing a textile product with a detergent for clothing containing the component (a), the component (b), and the component (c) (using a washing machine or hand washing).
The temperature of the treatment liquid (X) is preferably 1 to 40 ° C.
When the textile product is soaked in the treatment liquid (X), the soaking time (contact time between the treatment liquid (X) and the textile product) is preferably 1 minute to 12 hours, more preferably 1 minute to 2 Below time.
It is preferable to perform dehydration of the textile product after washing in a washing machine, hand washing, and soaking. In the case where a detergent for clothing containing the component (a), the component (b) and the component (c) is used, it is preferable to perform rinsing after washing and dehydration, and further dehydration.

-Method of spraying, dripping or applying the treatment liquid (X) to the textile product As a method of spraying, dropping or applying the treatment liquid (X) to the textile product (hereinafter also referred to as "method of spraying"), the treatment liquid ( Since X) easily permeates the fiber product uniformly, a method of spraying the treatment liquid (X) onto the fiber product is preferable. Specifically, the treatment liquid (X) is accommodated in a spray container, and from the spray container A method in which the treatment liquid (X) is sprayed directly onto the fibers can be mentioned.

Examples of the spray container include an aerosol spray container, a trigger spray container (direct pressure type or pressure accumulation type), a dispenser spray container, and the like.
Examples of the aerosol spray container include those described in JP-A-9-3441 and JP-A-9-58765. Examples of the propellant used for the aerosol spray container include LPG (liquefied propane gas), DME (dimethyl ether), carbon dioxide gas, nitrogen gas and the like. These may be used alone or in combination of two or more. May be used.
Examples of the trigger spray container include those described in JP-A-9-268473, JP-A-9-256272, JP-A-10-76196, and the like.
Examples of the dispenser spray container include those described in JP-A-9-256272.

As for the density | concentration of the process liquid (X) contacted with a textile product, 0.3 mass% or more is preferable, More preferably, it is 0.4-1 mass%, More preferably, it is 0.6-0.9 mass%. .
If the concentration of the treatment liquid (X) is not less than the preferable lower limit, a sufficient virus removal effect can be easily obtained. On the other hand, if the density | concentration of process liquid (X) is below the said preferable upper limit, it will be hard to damage a textiles.
“The concentration of the treatment liquid (X)” means the total content ratio of the component (a), the component (b), the component (c), and the other components contained in the treatment liquid (X).

Further, the concentration (mass basis) of the component (a) in the treatment liquid (X) is preferably 50 ppm or more, more preferably 100 to 5000 ppm, further preferably 1000 to 4000 ppm, and particularly preferably 1500 to 3000 ppm. . If it is less than 50 ppm, a sufficient virus removal effect may not be obtained.
The concentration (mass basis) of the component (b) in the treatment liquid (X) is preferably 10 ppm or more, more preferably 100 to 600 ppm, and still more preferably 200 to 500 ppm. If it is less than 10 ppm, a sufficient virus removal effect may not be obtained.
The concentration (mass basis) of the component (c) in the treatment liquid (X) is preferably 200 ppm or more, more preferably 1000 to 9000 ppm, still more preferably 2000 to 6000 ppm, and particularly preferably 3000 to 5000 ppm. If it is less than 200 ppm, a sufficient virus removal effect may not be obtained.

In the virus removal method for a textile product according to the present invention, the textile product brought into contact with the treatment liquid (X) in the first treatment step is composed of an aminocarboxylic acid, an aminocarboxylic acid salt, and a water-soluble metal salt. It is preferable that the treatment liquid (Y) containing at least one compound selected from the above and a cationic compound is further brought into contact (hereinafter, the treatment step for performing this operation is referred to as “second treatment step”).
By performing the operation of the second processing step in addition to the operation of the first processing step, the virus removal effect is further enhanced as compared with the case of performing only the operation of the first processing step.

<Second treatment process>
In the second treatment step, the treatment liquid (Y) is further brought into contact with the textile product in contact with the treatment liquid (X).

(Processing liquid (Y))
The treatment liquid (Y) comprises one or more compounds selected from the group consisting of aminocarboxylic acids, aminocarboxylates and water-soluble metal salts (hereinafter also referred to as “component (d)”) and cationic compounds (hereinafter referred to as “( e) also referred to as “component”).
The treatment liquid (Y) has an effect of inactivating viruses attached to the fibers. Although the mechanism of virus inactivation is not clear, the treatment liquid (Y) contains the component (d) in addition to the component (e) which is a cationic compound. The component (d) is a compound having a chelating effect, and it is considered that the virus is more easily inactivated by incorporating calcium in the virus into the component (d) due to the chelating effect.

-Component (d) The component (d) is one or more compounds selected from the group consisting of aminocarboxylic acids, aminocarboxylates, and water-soluble metal salts.

..Aminocarboxylic acid or salt thereof Aminocarboxylic acid or salt thereof (hereinafter also referred to as “component (d1)”) is a compound containing at least one amino group and one carboxy group in each molecule. The carboxy group present in the component (d1) may be a free form or a salt of an amine compound. The component (d1) may have a plurality of amino groups and carboxy groups in the molecule, and may further contain a functional group other than these in addition to the amino group and the carboxy group.

Examples of the component (d1) include methyl glycine diacetate (MGDA), aspartate diacetate (ASDA), isoserine diacetate (ISDA), β-alanine diacetate (ADAA), serine diacetate (SDA), and glutamate diacetate (GLDA). ), Iminodisuccinic acid (IDS), hydroxyiminodisuccinic acid (HIDS), ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid (NTA), diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), triethylenetetraamine 6 Acetic acid (TTHA), 1,3-propanediaminetetraacetic acid (PDTA), 1,3-diamino-2-hydroxypropanetetraacetic acid (DPTA-OH), hydroxyethyleneiminodiacetic acid (HIDA), dihydroxyethylglycine (DHE) ), Glycol ether diaminetetraacetic acid (GEDTA), dicarboxylate methyl glutamate (CMGA), (S, S) - ethylenediamine disuccinic acid (EDDS) or the salts thereof.
In addition to the above, as the component (d1), for example, sodium octylaminoacetate, sodium laurylaminoacetate, sodium myristylaminoacetate, sodium palmitylaminoacetate, sodium oleylaminoacetate or the like Aminoacetate salt; alkylaminopropionate or alkenylamino such as sodium octylaminopropionate, sodium decylaminopropionate, sodium laurylaminopropionate, sodium myristylaminopropionate, sodium palmitylaminopropionate, sodium oleylaminopropionate Propionate; N-octylglycine sodium, N-decylglycine sodium, N-laurylglycine sodium, N-myristylglycine na N-alkylglycine salts or alkenylglycine salts such as thorium, N-palmitylglycine sodium, N-oleylglycine sodium; N-octyl-N-methyl-β-alanine sodium, N-decyl-N-methyl-β-alanine Sodium, N-dodecyl-N-methyl-β-alanine sodium, N-myristyl-N-methyl-β-alanine sodium, N-palmityl-N-methyl-β-alanine sodium, N-oleyl-N-methyl-β N-alkyl-N-methyl-β-alanine or alkenyl-N-methyl-β-alanine salts such as sodium alanine; sodium octylaminodiacetate, sodium decylaminodiacetate, sodium laurylaminodiacetate, sodium myristylaminodiacetate , Sodium palmitate aminodiacetate Alkylaminodiacetate or alkenylaminodiacetate such as sodium oleylaminodiacetate; sodium octylaminodipropionate, sodium decylaminodipropionate, sodium laurylaminodipropionate, sodium myristylaminodipropionate, pal Examples thereof include alkylamino dipropionate or alkenylamino dipropionate such as sodium mytylaminodipropionate and sodium oleylaminodipropionate.
Among these, methylglycine diacetate (MGDA), aspartate diacetate (ASDA), isoserine diacetate (ISDA), β-alanine diacetate (ADAA), serine diacetate (SDA), glutamate diacetate (GLDA), iminodisuccinic acid ( IDS), hydroxyiminodisuccinic acid (HIDS) or a salt thereof is preferred, MGDA, IDS or a salt thereof is more preferred, and MGDA or a salt thereof is particularly preferred.

..Water-soluble metal salt The water-soluble metal salt (hereinafter also referred to as “component (d2)”) may be in the form of a hydrate.
“Water-soluble” in component (d2) means that the solubility at 25 ° C. is 0.1 g or more per 100 g of water.
Examples of the component (d2) include water-soluble silver salts, water-soluble copper salts, water-soluble zinc salts, water-soluble iron salts, water-soluble manganese salts, water-soluble aluminum salts, and hydrates thereof. However, a water-soluble silver salt, a water-soluble copper salt, a water-soluble zinc salt or a hydrate thereof is preferable, a water-soluble zinc salt, a water-soluble copper salt or a hydrate thereof is more preferable, and a water-soluble zinc salt or a hydrate thereof Hydrates are particularly preferred.
Specific examples of the water-soluble zinc salt include zinc nitrate (56.1 g), zinc sulfate (36.49 g), zinc chloride (77 g), zinc acetate (40.0 g), and the like. preferable.
Specific examples of the water-soluble copper salt include copper nitrate (60.8 g), copper sulfate (18.2 g), and copper chloride (75.7 g). Of these, copper sulfate hydrate is preferable, and copper sulfate pentahydrate is more preferable.
Specific examples of the water-soluble silver salt include silver sulfate (0.83 g: an amount dissolved in 100 g of water, hereinafter the same), silver nitrate (70.7 g), and the like.
Specific examples of the water-soluble iron salt include iron sulfate (29.5 g).
Specific examples of water-soluble manganese include manganese chloride (72.3 g).

(D) component contained in a processing liquid (Y) may be used individually by 1 type, and may use 2 or more types together.
Among these, the component (d) is preferably used in combination with the component (d1) and the component (d2) because the inactivation effect on the virus attached to the textile product contaminated with the sputum is further increased.
When the component (d1) and the component (d2) are used in combination, the mixing ratio (d2) / (d1) (molar ratio) between the component (d1) and the component (d2) is (d2) / (d1) = 0. 0.01-2 is preferable, 0.02-1 is more preferable, and 0.05-0.67 is more preferable. When (d2) / (d1) is equal to or more than the preferred lower limit, the deodorizing effect on the textiles contaminated with the vomit is also enhanced. On the other hand, it is easy to ensure the liquid stability of a process liquid (Y) as it is below a preferable upper limit.

When the component (d1) is used as the component (d), the content ratio of the component (d1) in the processing liquid (Y) is preferably a lower limit of 0.001 mass relative to the total mass of the processing liquid (Y). %, More preferably 0.05% by mass or more, further preferably 0.1% by mass or more, and the upper limit is preferably 15% by mass or less, more preferably 10% by mass or less.
When the component (d2) is used as the component (d), the content ratio of the component (d2) in the treatment liquid (Y) is preferably 0.001 to 10% by mass with respect to the total mass of the treatment liquid (Y). More preferably, it is 0.05-5 mass%.
When the component (d1) and the component (d2) are used in combination as the component (d), the total content ratio of the component (d1) and the component (d2) in the treatment liquid (Y) is the treatment liquid (Y). The amount is preferably 0.002 to 2% by mass, more preferably 0.3 to 1% by mass with respect to the total mass.
If the content rate of (d) component in a process liquid (Y) is more than the said preferable lower limit, the inactivation effect with respect to the virus adhering to a fiber will become easier to be acquired. On the other hand, if the content rate of (d) component is below the said preferable upper limit, the liquid stability of a process liquid (Y) will be maintained more easily.

-(E) component As (e) component (cationic compound), a water-soluble cationic compound and a water-insoluble cationic compound are mentioned. A water-soluble cationic compound may be used individually by 1 type, and may use 2 or more types together. The water-insoluble cationic compound may be used alone or in combination of two or more. Furthermore, as the component (e), a water-soluble cationic compound and a water-insoluble cationic compound may be used in combination.
In the present specification, “water-soluble” in a water-soluble cationic compound means a property of dissolving 1 g or more in 100 g of water at 25 ° C., and “water-insoluble” means that 100 g of water at 25 ° C. It means the property that the solubility is less than 1 g.

..Water-soluble cationic compound As the water-soluble cationic compound in component (e), preferably a neutralized product of a tertiary amine compound represented by the following general formula (III) or a quaternized product thereof, A neutralized product of a tertiary amine compound represented by the formula (IV) or a quaternized product thereof, and a water-soluble cationic polymer compound may be mentioned.

［式中、Ｒ^１は、エステル基、エーテル基又はアミド基を有していてもよい炭素数８〜２２の炭化水素基を表す。Ｒ^２ａ、Ｒ^２ｂ及びＲ^２ｃは、互いに同一でも異なっていてもよく、それぞれ炭素数１〜４のアルキル基又は炭素数２〜４のヒドロキシアルキル基を表す。Ｒ^３ａ及びＲ^３ｂは、互いに同一でも異なっていてもよく、それぞれエステル基、エーテル基又はアミド基を有していてもよい炭素数８〜１２の炭化水素基を表す。］

[Wherein, R ¹ represents a hydrocarbon group having 8 to 22 carbon atoms which may have an ester group, an ether group or an amide group. R ^2a , R ^2b and R ^2c may be the same as or different from each other, and each represents an alkyl group having 1 to 4 carbon atoms or a hydroxyalkyl group having 2 to 4 carbon atoms. R ^3a and R ^3b may be the same as or different from each other, and each represents a hydrocarbon group having 8 to 12 carbon atoms which may have an ester group, an ether group or an amide group. ]

... Neutralized product of tertiary amine compound or quaternized product thereof In formula (III), R ¹ is a hydrocarbon having 8 to 22 carbon atoms which may have an ester group, an ether group or an amide group. Represents a group.
The number of carbon atoms of the hydrocarbon group for R ¹ is 8 to 22, preferably 12 to 20, more preferably from 12 to 18. This carbon number does not include the carbon atom in the ester group or amide group that the hydrocarbon group may have.
Examples of the hydrocarbon group for R ¹ include a linear or branched alkyl group, or a linear or branched alkenyl group, and a linear or branched alkyl group is preferable. A chain alkyl group is more preferable.

In the formula (III), R ^2a and R ^2b may be the same or different from each other, and each represents an alkyl group having 1 to 4 carbon atoms or a hydroxyalkyl group having 2 to 4 carbon atoms.
R ^2a and R ^2b are preferably a methyl group, an ethyl group, a hydroxyethyl group, or a hydroxypropyl group, and more preferably a methyl group or a hydroxyethyl group.

In the formula (IV), R ^2c represents an alkyl group having 1 to 4 carbon atoms or a hydroxyalkyl group having 2 to 4 carbon atoms, preferably a methyl group, an ethyl group, a hydroxyethyl group, or a hydroxypropyl group, and a methyl group A hydroxyethyl group is more preferable.

In the formula (IV), R ^3a and R ^3b may be the same or different from each other, and each represents a hydrocarbon group having 8 to 12 carbon atoms which may have an ester group, an ether group or an amide group. .
Carbon number of the hydrocarbon group in R ^{< 3a>} , R ^<3b > is 8-12, Preferably it is 10-12. This carbon number does not include the carbon atom in the ester group or amide group that the hydrocarbon group may have.
Examples of the hydrocarbon group for R ^3a and R ^3b include a linear or branched alkyl group, or a linear or branched alkenyl group, and a linear or branched alkyl group includes A linear alkyl group is preferable.
Specific examples of R ^3a and R ^3b include a decyl group, a dodecyl group, and a decylyloxyethyl group.

The acid constituting the neutralized product of the tertiary amine compound represented by the general formula (III) or the general formula (IV) is not particularly limited, and preferred examples include hydrochloric acid, sulfuric acid, methyl sulfuric acid and the like.
As a method for obtaining a neutralized product of the tertiary amine compound, a method in which the tertiary amine compound represented by the general formula (III) or the general formula (IV) is directly neutralized with an acid; a treatment solution is prepared. In this case, a method of adding the tertiary amine compound to a liquid containing an acid in advance; a method of adding the tertiary amine compound and an acid simultaneously when preparing a treatment liquid, and the like.

  The quaternizing agent used for obtaining the quaternized product of the tertiary amine compound represented by the general formula (III) or the general formula (IV) is not particularly limited, and preferable examples include methyl chloride and dimethyl sulfate. Can be mentioned.

  Examples of neutralized or quaternized tertiary amine compounds represented by general formula (III) or general formula (IV) include stearyltrimethylammonium chloride, didecyldimethylammonium chloride, didodecyldimethylammonium chloride, stearoyloxyethyl. -N, N-dihydroxyethyl-N-methylammonium methylsulfate, N, N-didecylyloxyethyl-N-hydroxyethyl-N-methylammonium methylsulfate are preferable, and among these, stearyltrimethylammonium chloride, didecyl Especially dimethylammonium chloride, didodecyldimethylammonium chloride, stearoyloxyethyl-N, N-dihydroxyethyl-N-methylammonium methyl sulfate Masui.

  Specific examples of the neutralized or quaternized tertiary amine compound represented by the general formula (III) or general formula (IV) include ARCARD 12-37W (manufactured by Lion Akzo Co., Ltd.), ARCARD T-800. Alkyltrimethylammonium chloride such as Lion Lion Akzo Co., Ltd .; Didecyldimethylammonium chloride such as Archard 210 (Lion Akzo Corporation); Alkyldimethyldimethyl such as Arcade CB-50 (Lion Akzo Corporation) Benzyl ammonium chloride, benzalkonium chloride, benzethonium chloride and the like can be used, and among these, didecyldimethylammonium chloride such as Arcade 210 (manufactured by Lion Akzo Corporation) is particularly preferable.

... Water-soluble cationic polymer compound The water-soluble cationic polymer compound in component (e) preferably has a lower cationization degree of 0.1% or more, preferably 2.5% or more. Those are more preferred. More specifically, the cationization degree is preferably from 0.1 to 35%, more preferably from 2.5 to 20%. When the degree of cationization is in the above range, the effect of virus inactivation on the fiber tends to increase.

As used herein, “cationization degree” refers to a polymer compound of a cationic monomer, a copolymer of a cationic monomer and a nonionic monomer, or a part of a nonionic polymer modified with a cationic group. In the case of a substituted one (cationized cellulose or the like), it means a value calculated by the following formula (1).
Cation degree (%) = S × T × 100 (1)
S: Atomic weight of a cationized atom (such as nitrogen) in the cationic group of the polymer compound T: Number of moles of the cationic group contained in 1 g of the polymer compound

Further, when the polymer compound is a copolymer of a cationic monomer and an anionic monomer, or a copolymer of a cationic monomer, an anionic monomer and a nonionic monomer, it is calculated by the following formula (2). Value.
Cation degree (%) = S × (TU) × 100 (2)
S: Atomic weight of cationized atoms (nitrogen, etc.) in the cationic group of the polymer compound T: Number of moles of cationic group contained in 1 g of the polymer compound U: Anionic property contained in 1 g of the polymer compound Examples of the anionic group in the number of moles U of the group include a carboxy group and a sulfonic acid group contained in the monomer unit in the polymer chain. Specifically, it is a carboxy group in acrylic acid. However, the anionic group does not include a counter ion of the cationic group.

  According to the calculation method of the cationization degree, the cationization degree of the nonionic monomer polymer and the cationization degree of the anionic monomer polymer are both 0%.

  As an example of calculating the degree of cationization, a case of a water-soluble cationic polymer compound (MERQUAT280, manufactured by NALCO) composed of a copolymer having a repeating unit represented by the following chemical formula (V) is shown.

This cationic polymer compound (MERQUAT280) is a copolymer of a cationic monomer and an anionic monomer (monomer mass ratio of dimethyldiallylammonium chloride and acrylic acid = 80: 20).
S: 14 (atomic weight of nitrogen atom)
T: 4.95 × 10 ⁻³ mol (calculated from 0.8 g of the cationic group contained in 1 g of the cationic polymer compound and the molecular weight of the cationic group)
U: 2.78 × 10 ⁻³ mol (calculated from 0.2 g of anionic group contained in 1 g of cationic polymer compound and molecular weight of anionic group)
From the formula (2), the degree of cationization of the cationic polymer compound (MERQUAT280) is calculated as follows.
Cation degree (%) = S × (TU) × 100
= 14 × (4.95 × 10 ⁻³ -2.78 × 10 ⁻³ ) × 100
= 3.0

  The water-soluble cationic polymer compound in component (e) preferably has a weight average molecular weight of 1000 to 5000000, more preferably 3000 to 5000, measured by gel permeation chromatography using polyethylene glycol as a standard substance. It is 1000000, More preferably, it is 5000-500000. When the weight average molecular weight is within the above range, an increase in the viscosity of the treatment liquid is suppressed, and the usability of the treatment liquid is enhanced.

Specific examples of such water-soluble cationic polymer compounds include MERQUAT100 (manufactured by NALCO), Adeka thioace PD-50 (manufactured by Asahi Denka Kogyo Co., Ltd.), DAIDOL EC-004, DAIDOL HEC, DAIDOL EC (Daido Kasei). Dimethyldiallylammonium chloride / acrylic acid co-polymers such as dimethyl diallylammonium chloride / acrylamide copolymer such as MERQUAT550 JL5 (manufactured by NALCO), MERQUAT280 (manufactured by NALCO) Polymer, cationized cellulose such as Leogard KGP (manufactured by Lion Corporation), imidazolinium chloride / vinyl pyrrolidone copolymer such as LUVIQUAT-FC905 (manufactured by B / A / S / F), LUGALVAN-G15 Polyethyleneimine such as 000 (manufactured by B / A / S / F), cationized polyvinyl alcohol such as Poval CM318 (manufactured by Kuraray Co., Ltd.), natural polymer derivatives having amino groups such as chitosan, diethylamino methacrylate / ethylene oxide A copolymer with a vinyl monomer having a hydrophilic group to which etc. are added can be used.
Among these, a polymer of dimethyldiallylammonium chloride and cationized cellulose are particularly preferable.

.. Water-insoluble cationic compound (e) The water-insoluble cationic compound in component (e) is preferably a neutralized product of a tertiary amine compound represented by the following general formula (VI) or a quaternized product thereof. .

［式中、Ｒ^４ａ及びＲ^４ｂは、互いに同一でも異なっていてもよく、それぞれエステル基、エーテル基又はアミド基を有していてもよい炭素数１４〜２０の炭化水素基を表す。Ｒ^５は、エステル基、エーテル基もしくはアミド基を有していてもよい炭素数１４〜２０の炭化水素基、炭素数１〜４のアルキル基又は炭素数２〜４のヒドロキシアルキル基を表す。］

[Wherein, R ^4a and R ^4b may be the same or different from each other, and each represents a hydrocarbon group having 14 to 20 carbon atoms which may have an ester group, an ether group or an amide group. R ⁵ represents a hydrocarbon group having 14 to 20 carbon atoms, an alkyl group having 1 to 4 carbon atoms, or a hydroxyalkyl group having 2 to 4 carbon atoms, which may have an ester group, an ether group or an amide group. ]

In the formula (VI), R ^4a and R ^4b may be the same or different from each other, and each represents a hydrocarbon group having 14 to 20 carbon atoms which may have an ester group, an ether group or an amide group. .
Carbon number of the hydrocarbon group in R ^{< 4a>} , R ^<4b > is 14-20, Preferably it is 16-20, More preferably, it is 18-20. This carbon number does not include the carbon atom in the ester group or amide group that the hydrocarbon group may have.
Examples of the hydrocarbon group for R ^4a and R ^4b include a linear or branched alkyl group, or a linear or branched alkenyl group. A linear alkyl group or a linear Alkenyl groups are preferred.
Especially, the hydrocarbon group in R ^{< 4a>} , R ^<4b > has a preferable hydrocarbon group which may have an ester group or an amide group.

In the formula (VI), R ⁵ is a hydrocarbon group having 14 to 20 carbon atoms, an alkyl group having 1 to 4 carbon atoms or 2 to 4 carbon atoms which may have an ester group, an ether group or an amide group. Represents a hydroxyalkyl group.
The description of the hydrocarbon group having 14 to 20 carbon atoms that may have an ester group, an ether group or an amide group in R ⁵ is the same as the description of R ^4a and R ^4b .
As the alkyl group having 1 to 4 carbon atoms and the hydroxyalkyl group having 2 to 4 carbon atoms in R ⁵ , a methyl group, an ethyl group, a hydroxyethyl group, and a hydroxypropyl group are preferable, and a methyl group and a hydroxyethyl group are more preferable. .

The acid constituting the neutralized product of the tertiary amine compound represented by the general formula (VI) is not particularly limited, and preferred examples include hydrochloric acid, sulfuric acid, and methyl sulfuric acid.
As a method for obtaining a neutralized product of a tertiary amine compound represented by the general formula (VI), a method for obtaining a neutralized product of a tertiary amine compound represented by the general formula (III) or the general formula (IV); It is the same.

  The quaternizing agent used for obtaining the quaternized product of the tertiary amine compound represented by the general formula (VI) is not particularly limited, and preferable examples include methyl chloride and dimethyl sulfate.

  As a neutralized product of the tertiary amine compound represented by the general formula (VI) or a quaternized product thereof, distearyldimethylammonium chloride, dipalmityldimethylammonium chloride, N, N-distearoyloxyethyl-N-methyl , N-hydroxyethylammonium methyl sulfate, N, N-dioleoyloxyethyl-N-methyl, N-hydroxyethylammonium methyl sulfate are preferred, and among these, distearyldimethylammonium chloride, N, N-distearoyloxy Ethyl-N-methyl, N-hydroxyethylammonium methyl sulfate, N, N-dioleoyloxyethyl-N-methyl, N-hydroxyethylammonium methyl sulfate are particularly preferred.

(E) component contained in a processing liquid (Y) may be used individually by 1 type, and may use 2 or more types together.
Among these, as the component (e), a neutralized product of a tertiary amine compound represented by the general formula (III) or a quaternized product thereof, and a neutralized tertiary amine compound represented by the general formula (IV) Or a quaternized product thereof, a neutralized product of a tertiary amine compound represented by the general formula (VI) or a quaternized product thereof is preferable, and 3 represented by the general formula (III) from the viewpoint of virus inactivating effect. A neutralized product of a tertiary amine compound or a quaternized product thereof, a neutralized product of a tertiary amine compound represented by the general formula (IV) or a quaternized product thereof is more preferred, and a tertiary represented by the general formula (IV) A neutralized product of an amine compound or a quaternized product thereof is more preferable, and a quaternized product of a tertiary amine compound represented by the general formula (IV) is particularly preferable.

When the neutralized or quaternized compound of the tertiary amine compound represented by the general formula (III) or general formula (IV) is used as the component (e), the tertiary amine compound in the treatment liquid (Y) The content of the neutralized product or quaternized product is preferably 0.01 to 20% by mass, more preferably 0.05 to 5% by mass, based on the total mass of the treatment liquid (Y).
When a water-soluble cationic polymer compound is used as the component (e), the content of the water-soluble cationic polymer compound in the treatment liquid (Y) is based on the total mass of the treatment liquid (Y). 1-10 mass% is preferable, More preferably, it is 1-5 mass%.
When the neutralized product of the tertiary amine compound represented by the general formula (VI) or the quaternized product thereof is used as the component (e), the neutralized product of the tertiary amine compound in the treatment liquid (Y) or The content of the quaternized product is preferably 1 to 20% by mass, more preferably 1.5 to 16% by mass with respect to the total mass of the treatment liquid (Y).
If the content rate of (e) component in a process liquid (Y) is more than the said preferable lower limit, the virus removal performance will be exhibited favorable. On the other hand, if the content rate of (e) component is below the said preferable upper limit, (e) component will penetrate | penetrate a textile efficiently efficiently.

In particular, when the component (d1) is used as the component (d), the mixing ratio of the component (e) and the component (d1) in the treatment liquid (Y) is expressed by the mass expressed by the component (e) / (d1). The ratio is preferably 0.01 to 200, more preferably 0.1 to 20, still more preferably 0.1 to 10, and particularly preferably 0.2 to 5.
When the component (e) / component (d1) is within the above-mentioned preferred range, the virus inactivating effect is further enhanced. In addition, when the (e) component / (d1) component is equal to or greater than the above-mentioned preferable lower limit value, the virus removal performance is satisfactorily exhibited. Stability is better.

-Solvent The treatment liquid (Y) preferably uses water as a solvent from the viewpoint of ease of preparation, solubility in water when used, and the like.
The water to be used is preferably ion-exchanged water or distilled water from which metal ions such as heavy metals dissolved in water are removed from the viewpoint of the temporal stability of the treatment liquid (Y).
In the treatment liquid (Y), the content ratio of water is preferably 30% by mass or more, more preferably 50% by mass or more, and further preferably 70% by mass or more with respect to the total mass of the treatment liquid (Y).
When the water content is at least the preferred lower limit, the liquid stability of the treatment liquid (Y) over time becomes better.

As the solvent, in addition to water, a water-soluble solvent may be used. By using a water-soluble solvent, it becomes easy to uniformly disperse the component (e) in the treatment liquid (Y).
Examples of the water-soluble solvent include primary alcohols having 2 to 3 carbon atoms such as ethanol and 2-isopropanol; glycols having 2 to 6 carbon atoms such as ethylene glycol, propylene glycol and dipropylene glycol; glycerin and diethylene glycol monobutyl ether. And a polyhydric alcohol having 3 to 8 carbon atoms. Among these, ethanol, glycerin, and diethylene glycol monobutyl ether are preferable, and ethanol is particularly preferable.
As ethanol, 10% desodium benzoate / alcohol solution, or “description of denatured alcohol under the Alcohol Business Act” such as octaacetylated sucrose or brucine (Guideline for using alcohol (10th edition) [Division 2 ] Alcohol use permission application manual (August 2012 Ministry of Economy, Trade and Industry) It is preferable to use ethanol containing a small amount of denaturing agent.
A water-soluble solvent may be used individually by 1 type, and may use 2 or more types together.
When using a water-soluble solvent, 3-30 mass% is preferable with respect to the total mass of a processing liquid (Y), and, as for the content rate of the water-soluble solvent in a processing liquid (Y), More preferably, it is 5-20 mass%. Yes, more preferably 7 to 15% by mass. If the content rate of a water-soluble solvent is the said preferable range, solubility and liquid stability will improve more.

When the treatment liquid (Y) is sprayed onto the textile product, it is preferable to use ethanol or a mixed solvent of ethanol and other water-soluble solvent as the water-soluble solvent because it is easy to dry.
In this case, the content of the water-soluble solvent in the treatment liquid (Y) is preferably 5% by mass or more, more preferably 5 to 30% by mass, and still more preferably relative to the total mass of the treatment liquid (Y). 10 to 20% by mass.

-Other components The processing liquid (Y) may contain other components other than the component (d) and the component (e).
Examples of such other components include perfumes, silicone compounds, surfactants not corresponding to component (e), preservatives, pH adjusters, chelating agents, anti-staining agents, polymers, antibacterial agents, fungicides, repellents, Dispersants, pigments, antioxidants, thickeners, thickeners, ultraviolet absorbers and the like can be mentioned.

.. Fragrance The fragrance that can be used in the treatment liquid (Y) is the same as the fragrance exemplified in the description of the treatment liquid (X).
The content (mass basis) of the fragrance in the treatment liquid (Y) is preferably 1 ppm or more and 10 mass% or less, more preferably 5 ppm or more and 5 mass% or less with respect to the total mass of the treatment liquid (Y). .

.. Silicone compound By using a silicone compound, the permeability of the treatment liquid (Y) to the textile product is further increased.
Examples of the silicone compound include dimethyl silicone, polyether-modified silicone, methylphenyl silicone, carboxy-modified silicone, glycerin-modified silicone, and amino-modified silicone. Among these, polyether-modified silicone is preferable.

When the treatment liquid (Y) is sprayed on the textile product, the ratio of oxyethylene groups per molecule is preferably 20 to 80% by mass, more preferably 25 to 80% by mass, and still more preferably 35 to 80% by mass, It is particularly preferable to use 50 to 80% by mass of polyether-modified silicone. Since such a polyether-modified silicone has a moderately hydrophilic group, by using such a polyether-modified silicone, the permeability of the treatment liquid (Y) to the fiber product is further increased. Examples of the polyether-modified silicone include SH3771M (HLB13), SH3772M (HLB6), SH3773M (HLB8), and SH3775M (HLB5) manufactured by Toray Dow Corning Co., Ltd. Among these, among them, SH3771M, SH3772M, and SH3773M Is preferable, SH3771M and SH3773M are more preferable, and SH3771M is more preferable.
“HLB” indicates the hydrophilic-lipophilic balance of the compound. The HLB of the polyether-modified silicone is a value calculated by (ratio (% by mass) of oxyethylene groups in the silicone compound) / 5.
The content ratio of the silicone compound in the treatment liquid (Y) is preferably from 0.1 to 20 mass%, more preferably from 0.3 to 15 mass%, still more preferably 1 with respect to the total mass of the treatment liquid (Y). -10 mass%.

.. Surfactant not applicable to component (e) The treatment liquid (Y) may contain a surfactant not applicable to the component (e). As the surfactant not corresponding to the component (e), a nonionic surfactant is particularly preferable. In particular, when the treatment liquid (Y) is sprayed onto the fiber product, it is preferable to use a nonionic surfactant because the dispersion stability of the treatment liquid (Y) is increased.
Preferred examples of the nonionic surfactant include polyoxyethylene alkyl ethers and polyoxyethylene fatty acids having an alkyl group or alkenyl group having 10 to 22 carbon atoms and an average repeating number of oxyethylene groups of 10 to 100 mol. Alkyl (C1-3) ester, polyoxyethylene alkylamine having an average repeating number of oxyethylene groups of 10 to 100 mol, alkyl polyglucoside having an alkyl group or alkenyl group having 8 to 18 carbon atoms, average of oxyethylene groups Examples include hydrogenated castor oil having a repeating number of 20 to 100 mol. Among these, polyoxyethylene alkyl ether having an alkyl group having 10 to 14 carbon atoms and having an average oxyethylene group repeating number of 5 to 20 mol, and an average oxyethylene group repeating number of 30 to 50 mol Hardened castor oil is more preferred.

・ ・ Preservatives As antiseptics, from the viewpoint of suppressing the growth of bacteria on the target textiles and suppressing the generation of unpleasant odors, organic and antifungal agents are used. From the group which consists of 1 type can be used individually or in mixture of 2 or more types. Organic fungicides and fungicides include alcohol, phenol, aldehyde, carboxylic acid, ester, ether, nitrile, peroxide / epoxy, halogen, pyridine / quinoline, triazine, Examples include isothiazolones, imidazoles / thiazoles, anilides, biguanides, disulfides, thiocarbamates, carbohydrates, tropolones, and organometallics. Examples of inorganic antifungal agents include metal oxides and silver.

..PH adjuster The pH adjuster for adjusting the pH of the treatment liquid (Y) is, for example, hydrochloric acid, sulfuric acid, acetic acid, citric acid or the like as acid; alkali metal salt such as sodium hydroxide as alkali, triethanolamine Etc. can be used.

  The pH of the treatment liquid (Y) is preferably pH 4 to 10 from the viewpoint of the storage stability of the treatment liquid (Y) and the odor suppressing effect of the textile product contaminated with the vomit. Since the virus inactivating effect and the odor suppressing effect are further increased, the ratio is more preferably 6 to 10.

  The viscosity of the treatment liquid (Y) is preferably 10 mPa · s or less. When the treatment liquid (Y) is accommodated in a spray container and the treatment liquid (Y) is sprayed directly onto the fibers from the spray container, the viscosity of the treatment liquid (Y) is more preferably 5 mPa · s or less.

-Preparation method of processing liquid (Y) It does not specifically limit as a preparation method of processing liquid (Y), For example, the method etc. which dissolve or disperse | distribute (d) component and (e) component in a solvent are mentioned.

(Method of bringing the treatment liquid (Y) into contact with the textile product)
The method of bringing the treatment liquid (Y) into contact with the textile product can be appropriately selected depending on the usage situation, and the method of immersing the textile product in the treatment liquid (Y); spraying, dripping or applying the treatment liquid (Y) to the textile product. The method etc. are mentioned. The description of these methods is the same as the “immersion method” and “method of spraying” exemplified in the description of the first treatment step.
In the second treatment step, the treatment of bringing the treatment liquid (Y) into contact with the textile product may be repeatedly performed using these “immersion method” or “method of spraying”.

In order to bring the treatment liquid (Y) into contact with the textile product after the first treatment step, for example, the textile product that has been brought into contact with the treatment liquid (X) in the first treatment step is preferably rinsed. After dehydration, the treatment liquid (Y) may be brought into contact with the fiber product by the above-mentioned “immersion method” or “method of spraying”.
The dehydration here can be performed by a washing machine (standard course or the like) that is usually used in general households.
The moisture content of the fiber product after dehydration is preferably 40 to 100% by mass. If the moisture content of the fiber product after dehydration is not less than the preferable lower limit, the inactivation effect on the virus attached to the fibers by the second treatment step is further increased. When the water content is less than the above-mentioned preferable lower limit, the time from the contact of the treatment liquid (Y) with the fiber product to the drying of the fiber product is too short, and the treatment liquid (Y) sufficiently acts on the virus. There are cases where it is not possible. On the other hand, when the water content exceeds the above preferable upper limit value, the treatment liquid (Y) brought into contact with the fiber product is excessively diluted, and it is difficult to obtain the virus inactivating effect.
In addition, "the state where the moisture content of the fiber product is 40% by mass" means that the fiber product contains water for 40% by mass of the mass of the fiber product in a dry state not containing water (this is defined as 100). It means a state where 100 is increasing (100 increases to 140).

  Among the methods described above, the method of bringing the treatment liquid (Y) into contact with the textile product is preferably a method of spraying, dropping or applying the treatment liquid (Y) to the textile product (a method such as spraying). A method of spraying or applying (Y) is more preferable. Among them, the treatment liquid (Y) is accommodated in a spray container from the viewpoints of simplicity that can be easily carried out at home and the economics that a necessary amount of the treatment liquid (Y) can be brought into contact with the center of the contaminated site. A method of spraying the treatment liquid (Y) directly on the fibers from the spray container is particularly preferable.

  The amount of spray, dripping or coating of the treatment liquid (Y) on the fiber product depends on the state of the fiber product after the first treatment step, but the lower limit is preferably 5 mass with respect to the total mass of the fiber product in the dry state. % Or more, more preferably 10% by mass or more, and further preferably 20% by mass or more. An upper limit becomes like this. Preferably it is 100 mass% or less, More preferably, it is 80 mass% or less. If the amount of sprayed, dripped or applied amount of the treatment liquid (Y) on the textile is within the above range, the virus inactivating effect can be sufficiently obtained, and in addition, the drying property and the economic efficiency are excellent, which is preferable.

In the second treatment step, the adsorption amount of the component (d1) per gram of the fiber product is preferably 150 to 15000 μg, more preferably 300 to 10000 μg, more preferably 500 to 8000 μg is particularly preferable.
The amount of adsorption of component (d2) per gram of fiber product (anhydrous equivalent) is preferably 200 to 20000 μg, more preferably 500 to 15000 μg, and more preferably 500 to 10,000 μg per treatment. Particularly preferred.
If the amount of adsorption of component (d) (component (d1), component (d2)) is equal to or greater than the preferred lower limit, a virus inactivating effect is more easily obtained. On the other hand, if it is below the preferable upper limit value, the interaction with the component (e) is likely to work.

  In the second treatment step, the amount of the (e) component adsorbed per 1 g of the textile product is preferably 10 to 10000 μg, more preferably 50 to 8000 μg, and more preferably 100 to 100 μg. It is especially preferable to set it as 5000 micrograms. If the adsorption amount of (e) component is more than the preferable lower limit, the virus inactivation effect is more easily obtained. On the other hand, if it is below the preferable upper limit value, the interaction with the component (d) is likely to work.

In the virus removal method for a textile product of the present invention, the combination processing of the first processing step and the second processing step described above may be repeated. By repeating the treatment of the combination, the virus inactivation effect is further increased.
Moreover, the virus removal method for a textile product of the present invention may include steps other than the first processing step and the second processing step described above. For example, the virus removal effect of the second treatment step can be easily obtained by performing treatment using a general softener after the first treatment step.

Hereinafter, the present invention will be described in more detail using examples, but the present invention is not limited to these examples. In this example, “%” indicates “% by mass” unless otherwise specified.
The raw materials used in this example are as follows.

<Raw materials>
(Peroxide or hydrogen peroxide that dissolves in water to generate hydrogen peroxide: component (a))
a-1: Sodium percarbonate (trade name SPC-Z, manufactured by Mitsubishi Chemical Corporation) effective oxygen amount 10.9%.
a-2: Hydrogen peroxide (35% industrial hydrogen peroxide, manufactured by Mitsubishi Gas Chemical Company, Inc.).

(One or more compounds selected from the group consisting of compound (I) and compound (II): component (b))
b-1: OBS12, sodium dodecanoyloxybenzenesulfonate; OBS12 was blended by using a synthetic product (granulated product) obtained by the following synthesis method. The compounding quantity in a table | surface shows the mass% of OBS12.
b-2: OBC10, 4-decanoyloxybenzoic acid (manufactured by Mitsui Chemicals, Inc.).
b-3: NOBS, sodium nonanoyloxybenzenesulfonate; NOBS was blended by using a synthetic product (granulated product) obtained by the following synthesis method. The compounding quantity in a table | surface shows the mass% of NOBS.

[Synthesis of OBS12 granulated product]
Disperse 3000 g (15.3 mol) of sodium 4-hydroxybenzene sulfonate (manufactured by Kanto Chemical Co., Ltd., reagent) in advance in 9000 g of N, N-dimethylformamide (manufactured by Kanto Chemical Co., Ltd., reagent) with a stirrer. While stirring, 3347 g (15.3 mol) of lauric acid chloride (manufactured by Tokyo Chemical Industry Co., Ltd., reagent) was added dropwise at 50 ° C. over 30 minutes. Three hours after completion of the dropwise addition, N, N-dimethylformamide was distilled off at 100 ° C. under reduced pressure (0.5 to 1 mmHg (66.7 to 133.3 Pa)). After washing with acetone (manufactured by Kanto Chemical Co., Ltd., reagent), purification was performed by recrystallization in a water / acetone (= 1/1 mol) solvent to obtain crystals of sodium 4-dodecanoyloxybenzenesulfonate. . The yield was 90%.
70 parts by mass of sodium 4-dodecanoyloxybenzenesulfonate obtained, 20 parts by mass of PEG (polyethylene glycol # 6000M (trade name), manufactured by Lion Co., Ltd.), α-olefin sodium sulfonate powder product having 14 carbon atoms (Lipolane) PJ-400 (trade name, manufactured by Lion Co., Ltd.) 5 parts by mass is added to a total of 5000 g into Extrude Ohmic EM-6 (trade name, manufactured by Hosokawa Micron Co., Ltd.), kneaded and extruded. Obtained a noodle-like extrudate having a diameter of 0.8 mm. This extrudate (60 ° C.) and 5 parts by mass of A-type zeolite powder are supplied to Fitzmill DKA-3 (trade name, manufactured by Hosokawa Micron Corporation) and pulverized, and bleaching activity having an average particle size of about 700 μm A granulated product of the agent OBS12 was obtained.

[Synthesis of NOBS granules]
First, the synthesis of bleach activator 4-nonanoyloxybenzene sulfonate sodium as raw materials, sodium 4-hydroxybenzene sulfonate (manufactured by Kanto Chemical Co., Ltd., reagent), N, N-dimethylformamide (manufactured by Kanto Chemical Co., Ltd., Reagents), nonanoic acid chloride (manufactured by Tokyo Chemical Industry Co., Ltd., reagent), and acetone (manufactured by Kanto Chemical Co., Ltd., reagent) were used in the following manner.
3000 g (15.3 mol) of sodium 4-hydroxybenzenesulfonate dehydrated in advance was dispersed in 9000 g of N, N-dimethylformamide, and 2918 g (15.3 mol) of nonanoic acid chloride was added at 50 ° C. while stirring with a stirrer. It was added dropwise over 30 minutes. Reaction was performed after completion | finish of dripping for 3 hours, and N, N- dimethylformamide was distilled off at 100 degreeC under pressure reduction (0.5-1 mmHg). After washing with acetone, purification was performed by recrystallization in a water / acetone (= 1/1 mol) solvent to obtain crystals of sodium 4-nonanoyloxybenzenesulfonate. The yield was 91%.
The granulated product of bleach activator NOBS was obtained by pulverizing noodles obtained by mixing and extruding and granulating the obtained sodium 4-nonanoyloxybenzenesulfonate: 75 parts by mass and PEG 6000: 25 parts by mass. Obtained.

(Comparative component of component (b): component (b ′))
b′-1: TAED, ethylenediaminetetraacetic acid tetrasodium (manufactured by Tokyo Chemical Industry Co., Ltd., reagent).

(Inorganic alkaline agent: component (c))
c-1: Sodium carbonate, heavy sodium carbonate (product name soda ash, manufactured by Asahi Glass Co., Ltd.).

(One or more compounds selected from the group consisting of aminocarboxylic acid, aminocarboxylate and water-soluble metal salt: component (d))
d1-1: MGDA, trisodium methylglycine diacetate (manufactured by BASF).
d2-1: Zinc sulfate (II) (manufactured by Kanto Chemical Co., Inc.).

(Cationic compound: component (e))
e-1: Didecyldimethylammonium chloride (trade name Arcard 210, manufactured by Lion Akzo Corporation).

(Other ingredients)
Surfactant-containing particles: those obtained by the following preparation method. The composition of the surfactant-containing particles is shown below.
“Balance” indicating the proportion of sodium sulfate means the amount added so that the total amount (% by mass) of all the components included in the surfactant-containing particles is 100% by mass.
Composition of surfactant-containing particles (ratio to the total mass of the particles): MES 13% by mass, LAS salt 3% by mass, soap 2% by mass, nonionic surfactant 3% by mass, zeolite 13% by mass, MA agent 4% by mass %, Sodium sulfate balance, fluorescent whitening agent 0.1% by mass, perfume 0.2% by mass, enzyme 0.3% by mass, moisture 6.4% by mass.

[Preparation of surfactant-containing particles]
Water was put into a jacketed mixing tank equipped with a stirrer, and the temperature was adjusted to 60 ° C. To this, LAS salt and soap were added and stirred for 10 minutes. Subsequently, the MA agent was added. After further stirring for 10 minutes, a part of the powdered zeolite and sodium sulfate were added. The slurry was further stirred for 20 minutes to prepare a slurry for spray drying having a moisture content of 38% by mass, and then spray-dried using a counter-current spray drying tower at a hot air temperature of 280 ° C., with an average particle size of 320 μm and a bulk density of 0.30 g. / Cm ³ , 5% by mass moisture-dried particles were obtained.

  Next, an aqueous slurry of MES (water concentration 25% by mass) and a part of the nonionic surfactant are added and concentrated under reduced pressure with a thin-film dryer until the water content becomes 11% by mass. MES and the nonionic surfactant A mixed concentrate with was obtained.

  Spray-dried particles obtained above, mixed concentrate, 2.0 parts by weight of zeolite, 1.0 part by weight of a nonionic surfactant (except for spray addition), fluorescent whitening agent, water, Is added to a continuous kneader (KRC-S4, manufactured by Kurimoto Seiko Co., Ltd.), kneaded under conditions of a kneading capacity of 120 kg / hr and a temperature of 60 ° C. A mixture was obtained.

  While extruding the 6 wt% water-containing mixture obtained above using a pelleter double (FUJI POWAL Co., Ltd., EXDFJS-100 type) equipped with a die with a hole diameter of 10 mm, the cutter (Cutter peripheral speed was 5 m / s), and pellets having a length of about 5 to 30 mm were obtained.

  Next, 5.0 parts by mass of powdered zeolite (average particle size 180 μm) as a grinding aid is added to the obtained pellets, and the pellets are arranged in three stages in series in the presence of cold air (10 ° C., 15 m / s). (Screen hole diameter: 1st stage / 2nd stage / 3rd stage = 12 mm / 6 mm / 3 mm, rotation speed: 1st stage / 2 stages) using a Fitzmill (manufactured by Hosokawa Micron Corporation, DKA-3) (Each / third stage is 4700 rpm).

  Subsequently, the obtained pulverized product (powder) was mixed with a horizontal cylindrical rolling mixer (cylinder diameter: 585 mm, cylinder length: 490 mm, inner wall surface of drum of container 131.7 L, clearance between inner wall surface: 20 mm, height: 45 mm) 1.5 parts by weight of powdered zeolite and 0.5 parts by weight of a nonionic surfactant and a fragrance under the conditions of a filling rate of 30% by volume, a rotational speed of 22 rpm and 25 ° C. Were sprayed to roll for 1 minute to modify the surface to obtain particles.

  Next, an enzyme is added to the horizontal cylindrical rolling mixer, and the particles obtained above and the enzyme are mixed for 5 minutes under the conditions of a filling rate of 30% by volume, a rotational speed of 22 rpm, and 25 ° C. to obtain a surfactant. Contained particles (detergent composition) were obtained.

  The raw materials used for the preparation of the surfactant-containing particles are as follows.

MES: Sodium salt of fatty acid methyl ester sulfonate with 16 carbon atoms / 18 carbon atoms = 80/20 (mass ratio) (manufactured by Lion) AI = 70% by mass, the balance being unreacted fatty acid methyl ester, sodium sulfate, Methyl sulfate, hydrogen peroxide, water, etc.
LAS salt: LAS-H (linear alkyl (carbon number: 10 to 14) benzenesulfonic acid (product name: Lipon LH-200 (pure content: 96% by mass), manufactured by Lion Corporation)), concentration: 48% by mass potassium hydroxide Neutralized with an aqueous solution (the amount in the table indicates mass% as LAS-K (potassium)).
Soap: Fatty acid sodium having 12 to 18 carbon atoms (manufactured by Lion Corporation) 67% by mass pure, titer 40 to 45 ° C. Fatty acid composition: C12 (lauric acid) = 11.7 mass%, C14 = 0.4 mass%, C16 = 29.2 mass%, C18F0 (stearic acid) = 0.7 mass%, C18F1 (oleic acid) = 56 0.8% by mass, C18F2 (linoleic acid) = 1.2% by mass; molecular weight 289.
Nonionic surfactant: ECOROL26 (trade name, manufactured by ECOGREN; alcohol having an alkyl group having 12 to 16 carbon atoms) an average of 15 moles of ethylene oxide adduct; pure content of 90% by mass.
Zeolite: A-type zeolite (trade name: Shilton B, manufactured by Mizusawa Chemical Co., Ltd.) Pure content: 80% by mass;
MA agent: Acrylic acid / maleic anhydride copolymer sodium salt (trade name Aqualic TL-400, manufactured by Nippon Shokubai Co., Ltd.) 40 mass% aqueous solution.
Sodium sulfate: neutral anhydrous sodium sulfate (manufactured by Nippon Chemical Industry Co., Ltd.).
Fluorescent whitening agent: Chinopearl CBS-X (trade name, Ciba Specialty Chemicals) / Chinopearl AMS-GX (trade name, Ciba Specialty Chemicals) = 3/1 (mass ratio) mixture.
Perfume: Perfume composition A described in JP-A-2002-146399 [Table 11]-[Table 18].
Enzyme: Sabinase 12T (Novozymes) / LIPEX100T (Novozymes) / Stainzyme 12T (Novozymes) = 5/4 (mass ratio).

Cluster dextrin (registered trademark): Glico Nutrition Foods, Inc. The main component of Cluster Dextrin (registered trademark) has a molecular weight of about 30,000 to 1,000,000, has one cyclic structure in the molecule, and a weight average polymerization degree of 2500 having many glucan chains bonded to the cyclic portion. About dextrin. The cyclic structure portion is composed of about 16 to 100 glucoses, and many non-cyclic branched glucan chains are bonded to the cyclic structure.
Tea tree oil: Brand name essential oil tea tree, made by MUJI.
Polyether-modified silicone: trade name SH3771M, manufactured by Toray Dow Corning Co., Ltd.
Fragrance: A fragrance composition (a-1-1) described in Examples of JP-A-2008-7872.

<Preparation of treatment liquid (X)>
According to the composition shown in Tables 1 and 2 (blending components, mixing ratio (mass% display)), (a) component, (b) component or (b ′) component, (c) component, and surfactant-containing particles Were dissolved in water at a predetermined mixing ratio to prepare treatment solutions (X) as aqueous solutions having concentrations (ppm) shown in the table.
When there is a blank in the table, the blending component is not blended. The compounding amount of the component in each treatment liquid indicates a value of mass% as a pure component of the component.
The “treatment liquid concentration (ppm)” shown in the table is the sum of (a) component, (b) component or (b ′) component, (c) component, and surfactant-containing particles in the aqueous solution. Content ratio (mass basis).
The pH of the treatment liquid is determined by putting the pH electrode into the treatment liquid adjusted to 25 ° C. and reading the value after 2 minutes using a pH meter (pH meter: model number MP230, manufactured by Mettler Toledo). It was measured.

(Preparation of treatment liquids (X1) to (X9))
A mixture of a-1, b-1, b-2 or b-3, and c-1 is dissolved in water (purified water) to obtain treatment liquids (X1) to (X9), respectively. It was. The concentration (mass basis) of each treatment solution is shown below.
Treatment liquid (X1) 9000 ppm (0.9 mass%),
Treatment liquid (X2) 9000 ppm (0.9 mass%),
Treatment liquid (X3) 9000 ppm (0.9 mass%),
Treatment liquid (X4) 9000 ppm (0.9 mass%),
Treatment liquid (X5) 6000 ppm (0.6 mass%),
Treatment liquid (X6) 6000 ppm (0.6 mass%),
Treatment liquid (X7) 6000 ppm (0.6 mass%),
Treatment liquid (X8) 5000 ppm (0.5% by mass),
Treatment liquid (X9) 4000 ppm (0.4 mass%).

(Preparation of treatment liquids (X10) and (X11))
A mixture of a-1, b-1 or b-2, c-1, and surfactant-containing particles was dissolved in water to obtain treatment liquids (X10) and (X11), respectively. . The concentration (mass basis) of each treatment solution is shown below.
Treatment liquid (X10) 6000 ppm (0.6 mass%),
Treatment liquid (X11) 6000 ppm (0.6 mass%).

(Preparation of treatment liquid (X12))
A mixture of a-2 and b-1 was dissolved in water to obtain a treatment liquid (X12). The concentration of the treatment liquid (X12) is 4000 ppm (0.4 mass%).

(Preparation of treatment liquid (X13))
A mixture of a-1 and c-1 was dissolved in water to obtain a treatment liquid (X13). The concentration of the treatment liquid (X13) is 4000 ppm (0.4% by mass).

(Preparation of treatment liquid (X14))
A mixture of a-1 and b-1 was dissolved in water to obtain a treatment liquid (X14). The concentration of the treatment liquid (X14) is 500 ppm (0.05% by mass).

(Preparation of treatment liquid (X15))
A mixture of a-1 and b-2 was dissolved in water to obtain a treatment liquid (X15). The concentration of the treatment liquid (X15) is 3000 ppm (0.3 mass%).

(Preparation of treatment liquid (X16))
A mixture of a-1, b′-1, c-1, and surfactant-containing particles was dissolved in water to obtain a treatment liquid (X16). The concentration of the treatment liquid (X16) is 6000 ppm (0.6% by mass).

<Preparation of treatment liquid (Y)>
Component (d), component (e), other components, and water were mixed at a predetermined mixing ratio to prepare a treatment liquid (Y).
The compounding amount of the component in each treatment liquid indicates a value of mass% as a pure component of the component.
“Balance” indicating the content ratio of water means a blending amount added so that a total blending amount (% by mass) of all blending components included in the treatment liquid becomes 100% by mass.
The pH of the treatment liquid is determined by putting the pH electrode into the treatment liquid adjusted to 25 ° C. and reading the value after 2 minutes using a pH meter (pH meter: model number MP230, manufactured by Mettler Toledo). It was measured.

(Preparation of treatment liquid (Y1))
e-1, tea tree oil, polyether-modified silicone, and fragrance were mixed in advance. Subsequently, water (purified water) was added to the mixture, and then d1-1, d2-1 and cluster dextrin were added and mixed to obtain a treatment liquid (Y1). The composition of this treatment liquid (Y1) is shown below. The pH of the treatment liquid (Y1) was 4.0.
Composition of treatment liquid (Y1): 0.4% by mass of d1-1 (trisodium methylglycine diacetate), 0.5% by mass of d2-1 (zinc sulfate (II)), e-1 (didecyldimethylammonium chloride) ) 0.2% by mass, tea tree oil 0.003% by mass, polyether-modified silicone 0.2% by mass, perfume 0.003% by mass, water balance.

(Preparation of treatment liquid (Y2))
e-1, tea tree oil, polyether-modified silicone, and fragrance were mixed in advance. Subsequently, water (purified water) was added to the mixture, and then d1-1, d2-1 and cluster dextrin were added and mixed to obtain a treatment liquid (Y2). The composition of this treatment liquid (Y2) is shown below. The pH of the treatment liquid (Y2) was 4.
Composition of treatment liquid (Y2): 0.001% by weight of d1-1 (trisodium methylglycine diacetate), 0.001% by weight of d2-1 (zinc sulfate (II)), e-1 (didecyldimethylammonium chloride) ) 0.2% by mass, tea tree oil 0.003% by mass, polyether-modified silicone 0.2% by mass, perfume 0.003% by mass, water balance.

<Evaluation>
Using the treatment liquid (X), the treatment liquid (X), and the treatment liquid (Y), the virus inactivation effect was evaluated by the following evaluation method. The results are shown in Tables 4-6.

(Preparation of model sputum)
The model vomit was prepared by adding horse serum (2% by mass to the artificial gastric juice) as an organic component in the vomit to the artificial gastric juice.
The raw materials used are as follows.
Artificial gastric juice: 1000 mL of a solution obtained by adding 7.0 mL of hydrochloric acid and water to 2.0 g of sodium chloride was used. This solution is colorless and transparent, and its pH is about 1.2 (see: 14th revised Japanese Pharmacopoeia Disintegration Test Method, Test Solution No. 1).
Horse serum: manufactured by HyClone.
Sodium chloride: manufactured by Wako Pure Chemical Industries, Ltd.
Hydrochloric acid: Wako Pure Chemical Industries, Ltd.
Water: Millipore water.

(Preparation of virus solution)
A feline calicivirus solution was prepared as a virus solution.

As a test virus, feline calicivirus (norovirus substitute virus) was used.
Since norovirus culture systems have not been established, a method for confirming virus infectivity by using a feline calicivirus belonging to the same caliciidae as a substitute virus for norovirus is generally employed. Feline calicivirus is a pathogen of feline infectious disease called feline calicivirus infection, which is similar in structure to norovirus and has similar properties to norovirus.

-Preparation of feline kidney cells Inactivation treatment by incubating 3 mL of penicillin streptomycin mixed solution (SIGMA, P4333) in DULBECCO'S MODIFIED EAGLE'S MEDIUM (D-MEM, SIGMA, D6429) at 56 ° C for 30 minutes And 25 mL of fetal bovine serum (FBS, Fetal Clone III Hyclone, SH30109.03) was added to prepare a 5% FBS D-MEM culture solution.
The culture supernatant of a feline kidney cell (Crandell-Res feltine kidney cell, CRFK, ATCC strain CCL-94) cultured in a T-75 cell culture flask (IWAKI, 75 square centimeter, 270 mL, cantoneck, 3123-075) After discarding, 10 mL of Dulbecco's phosphate buffered saline (PBS (−)) kept at 37 ° C. was added to wash and drain the cell surface. As Dulbecco's phosphate buffered saline (PBS (-)), Phospate-Buffered Saline (trade name Dulbecco's phosphate buffer, manufactured by Invitrogen Corporation) was used.
2 mL of trypsin-EDTA (GIBCO, Tryp LE with Phenol Red 12605-028) at 37 ° C. was added thereto and allowed to stand at 37 ° C. for about 2 minutes, and the cells were detached from the flask.
Thereto, 8 mL of D-MEM culture solution containing no FBS was added, the cells were suspended and extracted, and the cells were precipitated by centrifugation at 800 rpm × 5 minutes.
The supernatant was removed, and about 8 mL of 5% FBS D-MEM culture solution was added to prepare a cell suspension.
10 mL of 5% FBS D-MEM culture solution was placed in a T-75 cell culture flask, 2 mL of cell suspension was added, and the cells were cultured at 37 ° C. for 3 to 4 days in a CO ₂ incubator.

-Preparation of CRFK for 96-well microplate evaluation According to the above (2-2-1), the cultured cells were diluted 1/3 to 1/7 with 5% FBS D-MEM culture solution, 0.2 mL each was added to the plate (Nunc, 167008), and cultured for 3 to 4 days in the same manner.

-Preparation of virus solution The culture supernatant of the T-75 culture flask in a state where the cultured cells were sufficiently grown (confluent) was removed and washed twice with 10 mL of PBS (-).
Feline calicivirus (Feline calicivirus F9 strain, FCV, ATCC strain VR-782) was suspended in PBS (−) to TCID1E4 / mL, and 1 mL thereof was added.
The mixture was stirred every 10 minutes and cultured at 37 ° C. for 1 hour, to which 12 mL of Opti-MEM (GIBCO, 31985-070) was added and cultured at 37 ° C.
The standard culture time was about 20 hours, and cell degeneration (CPE) was observed in about 90% of the cell culture area.
The culture supernatant was collected and centrifuged at 4000 rpm for 10 minutes, and the supernatant was filtered through a 0.2 micron membrane filter.
Thereafter, it was added to a centrifugal filter unit (Millipore, Amicon Ultra-15, 100 kDa, 50 mL container), centrifuged at 4000 rpm for 5 minutes, and about 80 mL of the culture supernatant was concentrated to about 1 mL to obtain a virus solution.

[Evaluation of virus inactivation effect (1): Examples 1 to 11, Comparative Examples 1 to 5]
Assuming the case where the textile product is contaminated with the vomit, 150 μL of the model vomit was used in the following evaluation.
In a test tube, 150 μL of the model sputum and 900 μL of the treatment solution (X) were inoculated with 100 μL of feline calicivirus solution, mixed well by vortexing, and allowed to act at room temperature for 10 minutes (stock solution). Thereafter, this stock solution was diluted and neutralized 10 times with PBS (−). Furthermore, in order to obtain the virus infectivity titer based on the 50% cultured cell infection concentration (TCID50 method), serial dilution was performed 10 times with PBS (-).
Next, CRFK cells cultured in a monolayer using 10% FCS (+) MEM in a 96-well plate are inoculated with 25 μL of the above serial dilutions in 4 wells, respectively, and contacted with feline calicivirus and CRFK cells. I let you. Furthermore, 100 μL of 0.2% FCS (+) MEM was overlaid and cultured in a CO ₂ gas furan vessel at 37 ° C. for 3 to 5 days.
Thereafter, observation was carried out under a microscope, and the dilution factor at which cytopathy caused by the virus was observed in half of the four wells (50%) was determined. The logarithm of the dilution factor was used as the virus infectivity value.
The blank virus infectivity titer was determined by carrying out in the same manner as in the case of using the treatment solution (X) except that the PBS (-) solution was used instead of the treatment solution (X). The virus of was used.
And the difference (decrease value from the virus infection titer of a blank) of the virus infectivity titer of a blank and the virus infection titer at the time of using a process liquid (X) was calculated | required.
The virus inactivation effect was evaluated according to the following evaluation criteria using the decrease value from the virus infection titer of this blank as an index.
Evaluation Criteria A: The decrease value from the virus infectivity value of the blank is 5.
(Double-circle): The reduction | decrease value from the virus infection titer of a blank is 4.
○: The decrease value from the virus infection value of the blank is 3.
(Triangle | delta): The decrease value from the virus infectivity value of a blank is 2-1.
X: The decrease value from the blank virus infectivity value is 0.

  The composition of 10% FCS (+) MEM used in the evaluation (1) of the virus inactivation effect is shown below.

  The TCID50 method followed literature (literature: Hierholzer J. C., Killington RA, Virus isolation and quantitation, In Mahy B. W. J., Kangro H. O. (ed.), Virology methods. Harcourt Brace & Company, London, pp. 25-46 (1996)).

  From the results shown in Tables 4 and 5, according to the virus removal methods of Examples 1 to 11 to which the present invention was applied, viruses attached to textile products contaminated with sputum were inactivated without using a chlorine bleach. I can confirm that I can do it.

[Evaluation of virus inactivation effect (2): Examples 12 to 15]
(I) Test Cloth In this evaluation, cotton kanakin (10 cm × 10 cm cotton gold width 3 (for JIS dyeing fastness test, compliant with JIS L0803, washed)) was used as the test cloth.

(Ii) Treatment of test cloth (Example 12)
First processing step:
From the test cloth, 0.4 g of the test cloth was cut out and placed in a vial. Next, the test cloth was inoculated with a mixture of 150 μL of model sputum previously mixed by vortex and 100 μL of feline calicivirus. Thereafter, 900 μL of the treatment liquid (X1) was inoculated (the treatment liquid (X1) was brought into contact with the test cloth) and allowed to act at room temperature for 10 minutes. Here, a virus having a blank virus infectivity value of 5 was used.

After allowing to act at room temperature for 10 minutes, the test cloth was taken out from the vial, put into a new vial containing 10 mL of sterilized tap water, vortexed for 10 seconds, and rinsed.
The test cloth after the rinsing treatment was again put into a new vial containing 10 mL of sterilized tap water, and the rinsing treatment was performed by vortexing for 10 seconds.
After rinsing twice, the test cloth is taken out, sandwiched between filter papers (ADVANTEC No. 2, diameter 90 mm), and water absorption (dehydration treatment) is performed until the moisture content becomes 100 ± 10% with respect to the mass of the test cloth. (The water content of the test cloth after dehydration was 101% by mass).

Second processing step:
A spray container (Style Guard wrinkles and odors for clean spray carrying, manufactured by Lion Corporation) containing the treatment liquid (Y1) was prepared in advance.
Then, 0.2 g of the treatment liquid (Y1) was sprayed from the spray container onto the test cloth after the dehydration treatment (the treatment liquid (Y1) was brought into contact with the test cloth).

(Example 13)
The test cloth was treated by performing the same operations as in Example 12 except that the treatment liquid (X1) was changed to the treatment liquid (X6) (the water content of the test cloth after the dehydration treatment was 100% by mass). ).

(Example 14)
The test cloth was treated by performing the same operations as in Example 12 except that the treatment liquid (X1) was changed to the treatment liquid (X9) (the water content of the test cloth after the dehydration treatment was 102% by mass). ).

(Example 15)
The test cloth was treated by performing the same operations as in Example 14 except that the treatment liquid (Y1) was changed to the treatment liquid (Y2) (the moisture content of the test cloth after the dehydration treatment was 100% by mass). ).

(Iii) Virus inactivation test In each case, after the last operation of the second treatment step, the cap of the vial containing the test cloth was closed and left to stand for 18 hours (the treatment solution was allowed to act on the virus). )
After standing for 18 hours, a solution in which the virus was induced with 10 mL of PBS (−) was used as a sample stock solution for infectivity titration measurement. This stock solution for measuring infectious titer was diluted 10-fold with PBS (-) and implanted in a 96-well plate, and then the infectious titer was measured according to the TCID50 method (based on Behrens-Karber method). The virus infectivity titer when treated with
Then, the difference between the blank virus infection titer (blank virus infection titer is 5) and the virus infection titer when treated in each case (reduced value from the blank virus infection titer) was obtained, and the above evaluation ( The virus inactivation effect was evaluated according to the same evaluation criteria as in 1).

  From the results shown in Table 6, after bringing the treatment liquid (X) into contact with the fibers, the inactivation effect on the virus attached to the fibers is further increased by bringing the specific treatment liquid (Y) into contact with the fibers. That can be confirmed.

Claims (2)

1 selected from the group consisting of a peroxide or hydrogen peroxide which dissolves in water to generate hydrogen peroxide, a compound represented by the following general formula (I) and a compound represented by the general formula (II) A method for removing a virus from a textile product, wherein the treatment liquid (X) containing the above compound and an inorganic alkaline agent is brought into contact with the textile product to remove viruses attached to the fiber.

[Wherein, R ¹⁰ and R ²⁰ each independently represents an alkyl group or an alkenyl group having 7 to 13 carbon atoms. M ¹ and M ² are each independently a hydrogen atom or a salt-forming cation. ] In the textile product contacted with the treatment liquid (X),
The fiber according to claim 1, wherein a treatment liquid (Y) containing at least one compound selected from the group consisting of an aminocarboxylic acid, an aminocarboxylic acid salt, and a water-soluble metal salt and a cationic compound is further contacted. Virus removal method for products.