JP2015036686A - Self moisture proof test paper and production method thereof - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide test paper exhibiting a self moisture proof function before using packaging, and a production method thereof.SOLUTION: Provided is the self moisture proof test paper and the production method thereof. In the production method, on the test paper, by slice-state adhesive pads 10 of a first end and a second end, a sample pad 20 penetrating to a sample, and a reaction substance discharge pad 30 for reaction substance of the sample, a result display pad 40 for displaying the reaction result of the reaction substance of the sample and a moisture absorption pad 50 are mainly disposed in series. The moisture absorption pad 50 is formed of mainly material absorbing moisture, so that during use for test, the excessive remaining liquid of the sample overflown from the sample pad 20 is absorbed by utilizing the moisture absorption property. In addition, before use of the packaging body, the moisture absorption pad absorbs moisture included in the packaging body, thereby forming the self moisture proof function.

Description

The present invention relates to a test paper and a method for producing the same, and particularly to a test paper having a self-dehumidifying / moisture-proof ability and a method for producing the same.

In recent years, with the development of medical equipment technology, home-use biosignal measuring instruments have become universal. For example, blood pressure meters, electronic thermometers, blood glucose meters, uric acid measuring devices, cholesterol measuring devices, mini-electrocardiographs, etc., the price of various ecological signal measuring devices varies, and their practicality is also different.
Some ecological signal measuring instruments must always collect and measure blood. For this reason, it is necessary to always measure with a medical test strip containing an enzyme. This is, for example, measurement of blood glucose, uric acid, total cholesterol, low density lipoprotein, high density lipoprotein, liver function index, triglycerides and the like. Although a medical test strip measuring instrument is adopted, the storage and maintenance of the equipment is very easy. However, storing medical test strips is not easy.

The reason why it is difficult to store the medical test paper is that the enzyme in the medical test paper absorbs moisture in the air, hydrolysis occurs, and the medical test paper becomes invalid. Therefore, it is necessary to store the medical test paper in a medical test paper bottle or packaging material having a good sealing effect. Furthermore, it is necessary to put a desiccant separately in the medical test paper bottle or the packaging material.

However, the cost of medical test paper bottles or packaging is high, and once the bottle is opened, all medical test papers have the problem of facing moisture. Users always have to end use within a certain period of time or store them again in a moisture-proof box. However, this also requires centralized storage, and there is a problem of inconvenience in use. In Republic of China Patent Publication No. M419571 “Packaging of Medical Test Paper for Capsule Type”, a capsule type medical test paper packaging has been submitted, including at least one base material and desiccant layer and at least one medical test paper It is. Among them, the base material includes a plurality of capsule structures, and each capsule structure includes one observation window. Further, the desiccant layer employs a material that changes color after absorbing moisture, and is disposed on the inner surface of each capsule structure. However, although the moisture absorption situation can be easily observed, the cost of such a packaging material is greatly increased.

Another relatively common package is one in which a pack-like desiccant is contained in the packaging material at the same time. However, this adds cost and the content space of the package must always take into account the volume of the desiccant, which increases the size of the package and makes it impossible to approximate the shape of the package to the shape of the test slice. Occupy.

A main object of the present invention is to provide a test paper having a self-moisture-proof function and a method for producing the same before using the packaging. A moisture absorption pad mainly composed of an element capable of absorbing moisture is used. In addition to using its absorbency, it absorbs the residual liquid of the specimen by water absorption, absorbs moisture remaining in the air around the test paper in the package, and keeps the test paper dry before using the package. This solves problems such as the complexity of the manufacturing process of known technology and the high cost of dehumidifying parts. The moisture-absorbing pad is assembled at the same time as each part to increase the speed of test paper production and packaging with self-moisture-proofing capability, and at the same time to reduce the shape of the packaging, so that precise packaging close to the shape of the specimen Is possible.

Based on the above-mentioned object, in the test paper of the present invention and the manufacturing method thereof, the test paper is mainly a slice-like adhesive pad having a first end and a second end, and a sample pad that accepts penetration of one specimen, the specimen The reactant release pad of the reactant, the result display pad for displaying the reaction result of the reactant of the sample, and the moisture absorption pad are combined in this order. The moisture absorption pad is mainly composed of a material that absorbs moisture, and absorbs excess moisture from the specimen due to its water absorption, and absorbs excess moisture from the air around the test paper in the package before opening. The test paper is prevented from being damaged by moisture. At the same time, the moisture absorbing pad is essentially an essential part, so the number of parts does not increase and the desiccant similar to drug storage often found in packaging is reduced, thereby reducing costs.

A subsequent object of the present invention is the moisture absorbing pad. It is woven in three-dimensional or sliced form with hydrophilic fibers, mixed with a desiccant that absorbs moisture therein, and the mixture can be combined before filling the layers, or before combining into hydrophilic fibers and yarns. Is the point of starting to absorb moisture remaining in the air in the package by contact with air.
A further object of the present invention is to arrange a linear production line at the time of production, based on the operation line of the adhesive pad, the sample pad on the belt at the same time with parallel speed, discharge pad, display pad, moisture absorption pad After the connection, a cutting device is provided before the end of the operation line, and the width of the finished product is negotiated based on fluctuations in the movement frequency.
The advantages and spirit of the invention may be further understood in the following detailed description and schematic of the invention.

The schematic diagram of the self-moisture-proof test paper of this invention. The schematic diagram of the manufacturing method of the self-moisture-proof test paper of this invention.

Refer to Figure 1. FIG. 1 is a cross-sectional view of the self-moisture-proof test paper of the present invention. As shown in FIG. 1, the self-moisture-proof test paper 1 (Lateral flow test strip) of the present invention mainly includes an adhesive pad 10 (Adhesive card) at a first end 101 and a second end 102, a sample pad 20 for specimen penetration, A reaction substance release pad 30 for a sample reactant, a result display pad 40 for displaying a reaction result of a sample reactant, and a moisture absorption pad 50 are included.
Among them, the sample pad 20 is formed on the first end 101 of the adhesive pad 10. Meanwhile, the reactant release pad 30 is formed on the adhesive pad 10 and contacts the sample pad 20. The result display pad 40 is formed on the adhesive pad 10 and contacts the reactant release pad 30. The moisture absorbing pad 50 is formed at the second end 102 of the adhesive pad 10, and excess liquid penetrating the sample pad 20 is absorbed by the moisture absorbing pad 50 along the pump path 51 through the pump path 51 that conducts both. . The pump path 51 is combined at least by contact between the moisture absorption pad 50 and the result display pad 40.

When the specimen is dropped on the sample pad 20, the moisture absorption pad 50 is mainly composed of a material that can absorb moisture. Therefore, the moisture absorption pad 50 mainly uses water absorption to pass the specimen and its opposite passage. Providing a capillary flow pumping force. In addition, the specimen is gradually diffused to the result display pad 40, and in this process, the reactant reacts with the specimen in the reactant release pad 30 and reacts with the result display pad 40 based on the original design of the test paper 1. Results are displayed (eg, colored slats).

In order for the specimen to be absorbed smoothly, a pump path 51 is constructed at least between the moisture absorption pad 50 and the result display pad 40, and the capillary flow pump force of the specimen is increased by utilizing the absorbability of the moisture absorption pad 50. provide. The constituent material of the moisture absorption pad 50 here is a three-dimensional lump or slice composed mainly of a water-absorbing polymer compound, and the three-dimensional component has a demand for siphon capillarity. Required and can be formed of filaments. The water-absorbing molecules can be filled in the interstices between the fibers, or combined between layers, or mixed before fiber yarn extraction, combined into a plastic material, and contacted with the air in the environment to make the package 600 It is possible to absorb excess moisture remaining inside the package after the packaging.
The moisture absorbing pad 50 is provided around the test paper 1 in order to eliminate problems such as the complexity of the manufacturing process and the high cost of the known technology by omitting the independent desiccant packaged together in the packaging material of the conventional method. By absorbing moisture in the air, a moisture-proof mechanism for similar products can be provided.

In the mounting, the moisture absorption pad 50 has a geometric three-dimensional shape and can absorb moisture in the air around the test paper 1 (eg, lump shape, slice shape, slat shape). The moisture absorbing pad 50 can be similar to a sliced desiccant, a film desiccant or dry paper. Moreover, in selection of the material of the moisture absorption pad 50, one or a combination from the following groups can be included in the dehumidifying function portion. (1) A water-reactive compound (eg, calcium chloride, calcium oxide, anhydrous phosphoric acid). (2) A highly water-absorbing substance (eg, silicon, polymer aggregate, sugarcane fiber, montmorillonite, activated carbon).

In order to provide a sufficient utilization state of the moisture absorbing pad 50, the self-moisture-proof test paper 1 can also be inserted by a coating case. In addition, the case of the test paper 1 can be a cassette type structure or a pen type (Midstream) structure, and the moisture absorption pad 50 can be a slit type test paper, a lump, or a cutting plan. It can be made into a roll-shaped finished product.
Refer to Figure 2. FIG. 2 is a schematic view of a method for producing a self-moisture-proof test paper of the present invention. As shown in FIG. 2, in the method of manufacturing a self-moisture-proof test paper of the present invention, an adhesive pad belt 100 having a first end 101 and a second end 102 is first provided, followed by a sample pad belt 200, a reactant release. The pad belt 300, the result display pad belt 400, and the belt-like moisture absorbing pad 500 are formed on the adhesive pad belt 100 in this order, and a belt-shaped test paper before cutting (Uncut lateral flow test sheet) is formed. Subsequently, a plurality of cut test papers 1 are formed through cutting. The cut test paper 1 or the roll-type semi-finished product is packaged in a package 600. The packaging operation includes packaging after packaging of a cassette type or pen type case containing the test paper 1.

Among them, the sample pad belt 200 is formed on the first end 101 of the adhesive pad belt 100 in the belt-shaped test paper before cutting, and the sample pad belt 100 is used to receive the penetration of the specimen. The reactant release pad belt 200 contacts the sample pad belt 200. The reactant release pad belt 300 has the reactant of the specimen. The result display pad belt 400 is in contact with the reactant release, and the result display pad belt 400 displays the reaction result of the reactant of the sample. The belt-like water absorption / absorption 500 can contact the result display pad. In addition, the belt-like moisture absorbing pad 500 is mainly composed of a moisture absorbing material, and provides the capillary flow pump force of the specimen using water absorption. While the test paper 1 is encapsulated, it simultaneously absorbs moisture in the air around the test paper 1 in the package.
It is hoped that the features and spirit of the present invention can be better understood through the above-described more specific statements. Also, it is hoped that the scope of the present invention is not limited by the specific examples disclosed above. In any case, the purpose is that various modifications and corresponding arrangements cover the scope of the patent scope that the present invention desires to apply for.

1 Self-moisture-proof test paper (Lateral flow test strip)
10 Adhesive card (Adhesive card)
101 First end 102 Second end 20 Sample pad
30 Conjugated pad
40 Result display pad (Membrane)
50 Absorbent pad
51 Pump Pass 100 Adhesive Pad Belt 200 Sample Pad Belt 300 Reactant Release Pad Belt 400 Result Display Pad Belt 500 Belt-like Moisture Absorbing Pad 600 Packaging 7 Cutting Device

Claims (10)

Self-moisture-proof test paper includes:
Sample pad: Used to accept specimen penetration.
Reactant release pad: One end is in contact with the sample pad and has the reactant of the analyte.
Result display pad: Used to display the reaction result of the reactant of the specimen, with one end contacting the reactant release pad.
Moisture absorption pad: One end is in contact with the result display pad, and the absorption pad is mainly composed of a water absorbent, has a capillary effect, and is conducted to the result display pad through a pump path at least. Capillary flow pumping power, and at the same time absorbs moisture in the air around the test strip in the packaged state. In the self-moisture-proof test paper described in claim 1, at least a pump path is formed between the moisture absorption pad and the sample pad, and the capillary flow pumping force of the specimen is provided by the water absorption of the moisture absorption pad. The moisture absorption pad of the self-moisture-proof test paper described in claim 1 has a geometric three-dimensional shape and can absorb moisture in the air around the test paper. The self-moisture test paper includes:
Sliced adhesive pad: having a first end and a second end.
Sample pad: formed at the first end of the adhesive pad to accept the penetration of the specimen.
Reactant release pad: formed on the adhesive pad and in contact with the sample pad and having the reactant of the analyte.
Result display pad: Displayed on the adhesive pad and in contact with the reactant release pad, and displays the reaction result of the reactant of the sample.
Moisture absorption pad: formed of the adhesive pad and made of a desiccant that is in contact with the result display pad and mainly absorbs moisture, has a capillary effect, and has a capillary flow pumping force of the sample by water absorption. And at the same time absorb at least moisture in the air in the test strip packaging. In the self-moisture test paper described in claim 4, a pump path is formed at least between the moisture absorption pad and the sample pad, and the capillary flow pumping force of the specimen is provided by utilizing the water absorption of the moisture absorption pad. To do. The moisture absorption pad of the self-moisture-proof test paper described in claim 4 has a geometric three-dimensional shape and can absorb moisture in the air around the test paper. The moisture absorption pad of the self-moisture-proof test paper described in claim 1 or claim 4 is a sliced desiccant, a film desiccant or a dry paper. The outer packaging of the self-moisture-proof test paper described in claim 1 or claim 4 is a cassette type structure, a slip type, a pen type (midstream) structure, a slice type semi-product, a roll type semi-product or a capsule type. can do. The manufacturing method of the self-moisture-proof test paper includes the following.
An adhesive pad belt having a first end and a second end.
The sample pad belt, the reactant release pad belt, the result display pad belt, and the belt-like moisture absorption pad are bonded on the adhesive pad belt in this order to form a pre-cut belt-like test paper.
In the belt-shaped test paper, the sample pad belt is coupled to the first end of the adhesive pad belt, and the sample pad belt can accept the penetration of the specimen. The reactant release pad belt contacts the sample pad belt. The reactant release pad belt has one reactant of the sample, the result display pad belt contacts the reactant release pad, and the result display pad belt displays the reaction result of the reactant of the sample. To do. The belt-like moisture absorbing pad comes into contact with the result display pad belt. The belt-like moisture absorption pad is mainly composed of a desiccant, and provides the capillary flow pump force of the specimen by water absorption, and simultaneously absorbs moisture in the air around the test paper. The manufacturing method of the self-moisture-proof test paper described in claim 9 further includes the following.
The belt-shaped test paper before cutting is cut to form a plurality of test papers.

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