JP2014535050A5 - - Google Patents
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- Publication number
- JP2014535050A5 JP2014535050A5 JP2014537743A JP2014537743A JP2014535050A5 JP 2014535050 A5 JP2014535050 A5 JP 2014535050A5 JP 2014537743 A JP2014537743 A JP 2014537743A JP 2014537743 A JP2014537743 A JP 2014537743A JP 2014535050 A5 JP2014535050 A5 JP 2014535050A5
- Authority
- JP
- Japan
- Prior art keywords
- probe
- short
- sequence
- long
- genomic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000523 sample Substances 0.000 claims description 52
- 108091033319 polynucleotide Proteins 0.000 claims description 21
- 102000040430 polynucleotide Human genes 0.000 claims description 21
- 239000002157 polynucleotide Substances 0.000 claims description 21
- 238000009396 hybridization Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 claims 19
- 206010009944 Colon cancer Diseases 0.000 claims 8
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 8
- 208000026350 Inborn Genetic disease Diseases 0.000 claims 6
- 208000016361 genetic disease Diseases 0.000 claims 6
- 230000008707 rearrangement Effects 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 206010006187 Breast cancer Diseases 0.000 claims 4
- 208000026310 Breast neoplasm Diseases 0.000 claims 4
- 208000034826 Genetic Predisposition to Disease Diseases 0.000 claims 4
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 4
- 101150110531 MLH1 gene Proteins 0.000 claims 4
- 101150033433 Msh2 gene Proteins 0.000 claims 4
- 206010033128 Ovarian cancer Diseases 0.000 claims 4
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 201000005202 lung cancer Diseases 0.000 claims 4
- 208000020816 lung neoplasm Diseases 0.000 claims 4
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 230000035772 mutation Effects 0.000 claims 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims 2
- 230000003252 repetitive effect Effects 0.000 claims 2
- 108091023043 Alu Element Proteins 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 208000018360 neuromuscular disease Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161553889P | 2011-10-31 | 2011-10-31 | |
| US61/553,889 | 2011-10-31 | ||
| PCT/IB2012/002423 WO2013064896A1 (en) | 2011-10-31 | 2012-10-30 | Method for identifying or detecting genomic rearrangements in a biological sample |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014535050A JP2014535050A (ja) | 2014-12-25 |
| JP2014535050A5 true JP2014535050A5 (https=) | 2016-08-18 |
Family
ID=47559567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014537743A Pending JP2014535050A (ja) | 2011-10-31 | 2012-10-30 | 生体試料におけるゲノム再編成を特定又は検出する方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US9133514B2 (https=) |
| EP (1) | EP2773770A1 (https=) |
| JP (1) | JP2014535050A (https=) |
| WO (1) | WO2013064896A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014532403A (ja) * | 2011-10-31 | 2014-12-08 | ゲノミク ビジョン | ゲノムモールスコードを分子コーミングと併用する乳癌及び卵巣癌遺伝子並びに遺伝子座ｂｒｃａ１及びｂｒｃａ２におけるゲノム再編成の検出、可視化、及び高解像度物理マッピングの方法 |
| US10227650B2 (en) | 2014-11-14 | 2019-03-12 | Athena Diagnostics, Inc. | Methods to detect a silent carrier of a null allele genotype |
| US20180150597A1 (en) * | 2016-11-29 | 2018-05-31 | Genomic Vision Sa | Method for optimal design of polynucleotides sequences for analysis of specific events in any genetic region of interest |
| US20220064742A1 (en) | 2018-11-30 | 2022-03-03 | Genomic Vision | Association between integration of viral as hpv or hiv genomes and the severity and/or clinical outcome of disorders as hpv associated cervical lesions or aids pathology |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2755149B1 (fr) * | 1996-10-30 | 1999-01-15 | Pasteur Institut | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
| US6828097B1 (en) | 2000-05-16 | 2004-12-07 | The Childrens Mercy Hospital | Single copy genomic hybridization probes and method of generating same |
| US20030017159A1 (en) * | 2001-05-02 | 2003-01-23 | Jerome Ritz | Immunogenic tumor antigens: nucleic acids and polypeptides encoding the same and methods of use thereof |
| WO2005123961A2 (en) * | 2004-06-14 | 2005-12-29 | Ambry Genetics Corporation | Approaches to identifying mutations associated with hereditary nonpolyposis colorectal cancer |
| US7985542B2 (en) * | 2006-09-07 | 2011-07-26 | Institut Pasteur | Genomic morse code |
| MX346524B (es) * | 2010-04-23 | 2017-03-23 | Genomic Vision | Diagnostico de infecciones virales mediante la deteccion de adn viral genómico e infeccioso mediante compatibilización molecular. |
-
2012
- 2012-10-30 WO PCT/IB2012/002423 patent/WO2013064896A1/en not_active Ceased
- 2012-10-30 JP JP2014537743A patent/JP2014535050A/ja active Pending
- 2012-10-30 EP EP12815761.7A patent/EP2773770A1/en not_active Ceased
- 2012-10-31 US US13/665,440 patent/US9133514B2/en active Active
-
2015
- 2015-08-03 US US14/816,397 patent/US20160032405A1/en not_active Abandoned
-
2017
- 2017-12-18 US US15/845,543 patent/US20180100202A1/en not_active Abandoned
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