JP2014528301A - 眼内注射デバイス - Google Patents
眼内注射デバイス Download PDFInfo
- Publication number
- JP2014528301A JP2014528301A JP2014533890A JP2014533890A JP2014528301A JP 2014528301 A JP2014528301 A JP 2014528301A JP 2014533890 A JP2014533890 A JP 2014533890A JP 2014533890 A JP2014533890 A JP 2014533890A JP 2014528301 A JP2014528301 A JP 2014528301A
- Authority
- JP
- Japan
- Prior art keywords
- delivery device
- needle
- layer
- drug delivery
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002347 injection Methods 0.000 title claims description 11
- 239000007924 injection Substances 0.000 title claims description 11
- 238000012377 drug delivery Methods 0.000 claims abstract description 20
- 239000000203 mixture Substances 0.000 claims abstract description 18
- 239000003814 drug Substances 0.000 claims description 14
- 229940079593 drug Drugs 0.000 claims description 11
- 239000003242 anti bacterial agent Substances 0.000 claims description 4
- 239000000645 desinfectant Substances 0.000 claims description 4
- 239000000243 solution Substances 0.000 claims description 4
- 230000035876 healing Effects 0.000 claims description 3
- 239000003550 marker Substances 0.000 claims description 3
- 230000000202 analgesic effect Effects 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 230000001737 promoting effect Effects 0.000 claims description 2
- 230000003115 biocidal effect Effects 0.000 claims 1
- 230000008901 benefit Effects 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 208000030533 eye disease Diseases 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 208000002780 macular degeneration Diseases 0.000 description 1
- 229940090048 pen injector Drugs 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000008247 solid mixture Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims (6)
- 薬剤送達デバイス(1)であって:
針(7);及び
針(7)の少なくとも、一部に連結された組成物の層(9)、ここで、組成物が低い粘度及び低い表面張力を有する、
を含んでなる、上記薬剤送達デバイス。 - さらに:
薬剤を含むバレル(3);及び
バレル(3)内部で軸方向に可動なプランジャー(5)、
を含んでなる、請求項1に記載の薬剤送達デバイス(1)。 - 層(9)が針(7)の遠位先端を覆っていない、請求項1又は2に記載の薬剤送達デバイス(1)。
- 層(9)が針(7)の全露出面を覆う、請求項1〜3のいずれか一項に記載の薬剤送達デバイス(1)。
- 組成物が、消毒剤、治癒を促進するための溶液、鎮痛剤、抗生物質、薬剤、マーカー、及び、抗菌剤の少なくとも1つを含む、請求項1〜4のいずれか一項に記載の薬剤送達デバイス(1)。
- 層(9)が、注射部位と接触すると変形する、請求項1〜5のいずれか一項に記載の薬剤送達デバイス(1)。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11184410.6 | 2011-10-07 | ||
EP11184410.6A EP2578190A1 (en) | 2011-10-07 | 2011-10-07 | Intraocular injection device |
PCT/EP2012/069608 WO2013050462A1 (en) | 2011-10-07 | 2012-10-04 | Intraocular injection device |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2014528301A true JP2014528301A (ja) | 2014-10-27 |
JP6116572B2 JP6116572B2 (ja) | 2017-04-19 |
Family
ID=46968239
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014533890A Active JP6116572B2 (ja) | 2011-10-07 | 2012-10-04 | 眼内注射デバイス |
Country Status (5)
Country | Link |
---|---|
US (1) | US20140236098A1 (ja) |
EP (2) | EP2578190A1 (ja) |
JP (1) | JP6116572B2 (ja) |
CN (1) | CN103796620B (ja) |
WO (1) | WO2013050462A1 (ja) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
CN104758118B (zh) | 2010-10-15 | 2018-04-06 | 科尼尔赛德生物医学公司 | 用于进入眼睛的装置 |
CN104884049A (zh) | 2012-11-08 | 2015-09-02 | 克莱尔塞德生物医学股份有限公司 | 用于在人类受试者中治疗眼部疾病的方法和装置 |
CN110302004B (zh) | 2013-05-03 | 2023-04-28 | 科尼尔赛德生物医学公司 | 用于眼部注射的设备和方法 |
US10188550B2 (en) | 2013-06-03 | 2019-01-29 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
JP2017524419A (ja) | 2014-06-20 | 2017-08-31 | クリアサイド バイオメディカル,インコーポレイテッド | 薬剤送達のための挿入深さを制御するための可変径カニューレ及び方法 |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
WO2017139375A1 (en) | 2016-02-10 | 2017-08-17 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
CA3062845A1 (en) | 2016-05-02 | 2017-11-09 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
CN110177527B (zh) | 2016-08-12 | 2022-02-01 | 科尼尔赛德生物医学公司 | 用于调节药剂递送用针的插入深度的装置和方法 |
WO2018128876A1 (en) * | 2017-01-03 | 2018-07-12 | Vitrean, Inc. | Methods and devices for treating a retinal detachment |
CA3076366C (en) | 2017-09-22 | 2023-05-16 | Becton, Dickinson And Company | 4% trisodium citrate solution for use as a catheter lock solution |
CN113226229B (zh) | 2018-10-24 | 2023-12-22 | 新世界医学有限公司 | 眼科装置 |
US10722397B2 (en) | 2018-10-24 | 2020-07-28 | New World Medical, Inc. | Ophthalmic device |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08150215A (ja) * | 1994-11-30 | 1996-06-11 | Olympus Optical Co Ltd | 薬剤投与用処置具 |
JP2005515838A (ja) * | 2002-01-28 | 2005-06-02 | ディーエスユー・メディカル・コーポレーション | カニューレ用高粘性率抗菌剤 |
WO2006138719A2 (en) * | 2005-06-17 | 2006-12-28 | Georgia Tech Research Corporation | Coated microstructures and method of manufacture thereof |
JP2010131123A (ja) * | 2008-12-03 | 2010-06-17 | Medorekkusu:Kk | マイクロニードルアレイへの薬剤担持法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5674192A (en) * | 1990-12-28 | 1997-10-07 | Boston Scientific Corporation | Drug delivery |
US5358491A (en) * | 1993-09-13 | 1994-10-25 | Sterling Winthrop Inc. | Cartridge-needle unit having retractable needle |
RU2074699C1 (ru) * | 1993-10-18 | 1997-03-10 | Савельев Александр Викторович | Способ гляциопунктуры и игла для его осуществления |
US6335383B1 (en) * | 1994-10-18 | 2002-01-01 | Ethicon, Inc. | Microdispersions for coating surgical devices |
US6558686B1 (en) * | 1995-11-08 | 2003-05-06 | Baylor College Of Medicine | Method of coating medical devices with a combination of antiseptics and antiseptic coating therefor |
US7344499B1 (en) * | 1998-06-10 | 2008-03-18 | Georgia Tech Research Corporation | Microneedle device for extraction and sensing of bodily fluids |
US6623457B1 (en) * | 1999-09-22 | 2003-09-23 | Becton, Dickinson And Company | Method and apparatus for the transdermal administration of a substance |
US6613025B1 (en) * | 2000-05-25 | 2003-09-02 | Scimed Life Systems, Inc. | Method and apparatus for diagnostic and therapeutic agent delivery |
US20050251095A1 (en) * | 2004-05-07 | 2005-11-10 | Giap Brandon C | Improved medication injection device |
CA2622573A1 (en) * | 2005-09-16 | 2007-03-29 | (Osi) Eyetech, Inc. | Ophthalmic syringe |
WO2007050565A2 (en) * | 2005-10-25 | 2007-05-03 | Baylor College Of Medicine | Incorporation of antimicrobial combinations onto devices to reduce infection |
US7918814B2 (en) * | 2006-05-02 | 2011-04-05 | Georgia Tech Research Corporation | Method for drug delivery to ocular tissue using microneedle |
US9511016B2 (en) * | 2007-06-12 | 2016-12-06 | Epicentrx, Inc. | Topical composition for treating pain |
US20090062737A1 (en) * | 2007-08-28 | 2009-03-05 | Sun William Y | Ice coated hypodermic needle |
US20100042137A1 (en) * | 2008-02-19 | 2010-02-18 | Oronsky Bryan T | Acupuncture and acupressure therapies |
US8409606B2 (en) * | 2009-02-12 | 2013-04-02 | Incept, Llc | Drug delivery through hydrogel plugs |
CA2795096C (en) * | 2010-03-31 | 2021-10-26 | Ocuject, Llc | Device and method for intraocular drug delivery |
WO2013028936A1 (en) * | 2011-08-23 | 2013-02-28 | Itech Jv Development Company, Llc | Systems and methods for performing an injection |
-
2011
- 2011-10-07 EP EP11184410.6A patent/EP2578190A1/en not_active Ceased
-
2012
- 2012-10-04 JP JP2014533890A patent/JP6116572B2/ja active Active
- 2012-10-04 CN CN201280044420.9A patent/CN103796620B/zh not_active Expired - Fee Related
- 2012-10-04 US US14/348,596 patent/US20140236098A1/en not_active Abandoned
- 2012-10-04 EP EP12767007.3A patent/EP2775971A1/en not_active Withdrawn
- 2012-10-04 WO PCT/EP2012/069608 patent/WO2013050462A1/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08150215A (ja) * | 1994-11-30 | 1996-06-11 | Olympus Optical Co Ltd | 薬剤投与用処置具 |
JP2005515838A (ja) * | 2002-01-28 | 2005-06-02 | ディーエスユー・メディカル・コーポレーション | カニューレ用高粘性率抗菌剤 |
WO2006138719A2 (en) * | 2005-06-17 | 2006-12-28 | Georgia Tech Research Corporation | Coated microstructures and method of manufacture thereof |
JP2010131123A (ja) * | 2008-12-03 | 2010-06-17 | Medorekkusu:Kk | マイクロニードルアレイへの薬剤担持法 |
Also Published As
Publication number | Publication date |
---|---|
CN103796620A (zh) | 2014-05-14 |
EP2578190A1 (en) | 2013-04-10 |
US20140236098A1 (en) | 2014-08-21 |
EP2775971A1 (en) | 2014-09-17 |
WO2013050462A1 (en) | 2013-04-11 |
CN103796620B (zh) | 2017-04-19 |
JP6116572B2 (ja) | 2017-04-19 |
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