JP2014527061A5 - - Google Patents
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- Publication number
- JP2014527061A5 JP2014527061A5 JP2014527322A JP2014527322A JP2014527061A5 JP 2014527061 A5 JP2014527061 A5 JP 2014527061A5 JP 2014527322 A JP2014527322 A JP 2014527322A JP 2014527322 A JP2014527322 A JP 2014527322A JP 2014527061 A5 JP2014527061 A5 JP 2014527061A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- imidazol
- carbonyl
- hcv
- biphenylyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 *C(N(C(CCC1)C1C1)C1c1ncc(-c2ccc3-c4cc(-c5cnc(C(CC6C7CCC6)N7C(*)=O)[n]5)ccc4-c3c2)[n]1)=O Chemical compound *C(N(C(CCC1)C1C1)C1c1ncc(-c2ccc3-c4cc(-c5cnc(C(CC6C7CCC6)N7C(*)=O)[n]5)ccc4-c3c2)[n]1)=O 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161526798P | 2011-08-24 | 2011-08-24 | |
| US61/526,798 | 2011-08-24 | ||
| US201161529358P | 2011-08-31 | 2011-08-31 | |
| US61/529,358 | 2011-08-31 | ||
| US201261617813P | 2012-03-30 | 2012-03-30 | |
| US61/617,813 | 2012-03-30 | ||
| PCT/US2012/052216 WO2013028953A1 (en) | 2011-08-24 | 2012-08-24 | Combination treatments for hepatitis c |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017083252A Division JP2017165746A (ja) | 2011-08-24 | 2017-04-20 | Ｃ型肝炎の組合せ治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014527061A JP2014527061A (ja) | 2014-10-09 |
| JP2014527061A5 true JP2014527061A5 (https=) | 2015-10-08 |
Family
ID=47746891
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014527322A Pending JP2014527061A (ja) | 2011-08-24 | 2012-08-24 | Ｃ型肝炎の組合せ治療 |
| JP2017083252A Pending JP2017165746A (ja) | 2011-08-24 | 2017-04-20 | Ｃ型肝炎の組合せ治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017083252A Pending JP2017165746A (ja) | 2011-08-24 | 2017-04-20 | Ｃ型肝炎の組合せ治療 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20140234253A1 (https=) |
| EP (1) | EP2747569A4 (https=) |
| JP (2) | JP2014527061A (https=) |
| KR (1) | KR20140065427A (https=) |
| CN (1) | CN103917095A (https=) |
| AU (1) | AU2012298750A1 (https=) |
| BR (1) | BR112014004182A2 (https=) |
| CA (1) | CA2845321A1 (https=) |
| CL (1) | CL2014000428A1 (https=) |
| CO (1) | CO6890100A2 (https=) |
| CR (1) | CR20140086A (https=) |
| EA (1) | EA201490254A1 (https=) |
| HK (1) | HK1198869A1 (https=) |
| IL (1) | IL230844A0 (https=) |
| MX (1) | MX2014002171A (https=) |
| PH (1) | PH12014500386A1 (https=) |
| SG (1) | SG2014010490A (https=) |
| WO (1) | WO2013028953A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102480971B (zh) * | 2009-09-04 | 2014-11-26 | 杨森制药公司 | 化合物 |
| MX2014001833A (es) * | 2011-08-17 | 2014-02-27 | Glaxosmithkline Llc | Metodos terapeuticos. |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| EP2583677A3 (en) | 2011-10-21 | 2013-07-03 | Abbvie Inc. | Methods for treating HCV comprising at least two direct acting antiviral agent, ribavirin but not interferon. |
| DE202012012955U1 (de) | 2011-10-21 | 2014-07-14 | Abbvie Inc. | Eine Kombination aus mindestens zwei direkt wirkenden antiviralen Wirkstoffen (DAAs) für die Verwendung zur Behandlung von HCV |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| US9326973B2 (en) | 2012-01-13 | 2016-05-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US9447132B2 (en) | 2013-04-12 | 2016-09-20 | Achillion Pharmaceuticals, Inc. | Highly active nucleoside derivative for the treatment of HCV |
| US20150023913A1 (en) | 2013-07-02 | 2015-01-22 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
| WO2015005901A1 (en) * | 2013-07-09 | 2015-01-15 | Bristol-Myers Squibb Company | Combinations of hepatitis c virus inhibitors |
| US9775831B2 (en) | 2013-07-17 | 2017-10-03 | Bristol-Myers Squibb Company | Combinations comprising biphenyl derivatives for use in the treatment of HCV |
| CN104725365B (zh) * | 2013-12-23 | 2019-02-26 | 南京圣和药业股份有限公司 | 丙型肝炎病毒抑制剂及其应用 |
| US9512108B2 (en) * | 2013-12-31 | 2016-12-06 | Nanjing Sanhome Pharmaceutical Co., Ltd. | 9,9,10,10-Tetrafluoro-9,10-dihydrophenanthrene hepatitis C virus inhibitor and application thereof |
| CN106279122A (zh) * | 2014-01-21 | 2017-01-04 | 杭州普晒医药科技有限公司 | 一种化合物的盐及晶型或无定型物、其制备方法、含有它们的药物组合物和用途 |
| SG11201703645XA (en) * | 2014-11-10 | 2017-06-29 | Glaxosmithkline Intellectual Property (No 2) Ltd | Long acting pharmaceutical compositions for hepatitis c |
| MA41812A (fr) * | 2015-03-27 | 2018-01-30 | Janssen Pharmaceuticals Inc | Procédés et intermédiaires pour la préparation d'un inhibiteur de protéase macrocyclique du vhc |
| WO2017023631A1 (en) | 2015-08-06 | 2017-02-09 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| EA201892448A1 (ru) | 2016-04-28 | 2019-06-28 | Эмори Юниверсити | Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения |
| CN110693887B (zh) * | 2019-05-17 | 2022-06-17 | 歌礼药业（浙江）有限公司 | 包含索磷布韦和拉维达韦的片剂及其制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100158862A1 (en) * | 2006-08-11 | 2010-06-24 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US8303944B2 (en) * | 2006-08-11 | 2012-11-06 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8329159B2 (en) * | 2006-08-11 | 2012-12-11 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7704992B2 (en) * | 2008-02-13 | 2010-04-27 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US20110229438A1 (en) * | 2008-10-09 | 2011-09-22 | Anadys Pharmaceuticals, Inc. | Method of inhibiting hepatitus c virus by combination of a 5,6-dihydro-1h-pyridin-2-one and one or more additional antiviral compounds |
| US8729077B2 (en) * | 2008-11-28 | 2014-05-20 | Glaxosmithkline Llc | Anti-viral compounds, compositions, and methods of use |
| JP2012514605A (ja) * | 2009-01-07 | 2012-06-28 | サイネクシス，インコーポレーテッド | Ｈｃｖおよびｈｉｖ感染の治療への使用におけるシクロスポリン誘導体 |
| HUE030465T2 (hu) * | 2009-05-13 | 2017-05-29 | Antivirális vegyületek | |
| CN102480971B (zh) * | 2009-09-04 | 2014-11-26 | 杨森制药公司 | 化合物 |
| US8415374B2 (en) * | 2009-10-12 | 2013-04-09 | Bristol-Myers Squibb Company | Combinations of hepatitis C virus inhibitors |
| US8377980B2 (en) * | 2009-12-16 | 2013-02-19 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| MX2012006877A (es) * | 2009-12-18 | 2012-08-31 | Idenix Pharmaceuticals Inc | Inhibidores de virus de hepatitis c de arileno o heteroarileno 5, 5 - fusionado. |
| WO2012040126A1 (en) * | 2010-09-22 | 2012-03-29 | Alios Biopharma, Inc. | Substituted nucleotide analogs |
-
2012
- 2012-08-24 WO PCT/US2012/052216 patent/WO2013028953A1/en not_active Ceased
- 2012-08-24 EA EA201490254A patent/EA201490254A1/ru unknown
- 2012-08-24 EP EP12826268.0A patent/EP2747569A4/en not_active Withdrawn
- 2012-08-24 US US14/240,420 patent/US20140234253A1/en not_active Abandoned
- 2012-08-24 BR BR112014004182A patent/BR112014004182A2/pt not_active IP Right Cessation
- 2012-08-24 MX MX2014002171A patent/MX2014002171A/es unknown
- 2012-08-24 SG SG2014010490A patent/SG2014010490A/en unknown
- 2012-08-24 CN CN201280052257.0A patent/CN103917095A/zh active Pending
- 2012-08-24 JP JP2014527322A patent/JP2014527061A/ja active Pending
- 2012-08-24 HK HK14112612.7A patent/HK1198869A1/xx unknown
- 2012-08-24 CA CA2845321A patent/CA2845321A1/en not_active Abandoned
- 2012-08-24 PH PH1/2014/500386A patent/PH12014500386A1/en unknown
- 2012-08-24 AU AU2012298750A patent/AU2012298750A1/en not_active Abandoned
- 2012-08-24 KR KR1020147007736A patent/KR20140065427A/ko not_active Withdrawn
-
2014
- 2014-02-06 IL IL230844A patent/IL230844A0/en unknown
- 2014-02-21 CL CL2014000428A patent/CL2014000428A1/es unknown
- 2014-02-24 CR CR20140086A patent/CR20140086A/es unknown
- 2014-02-26 CO CO14040944A patent/CO6890100A2/es unknown
-
2017
- 2017-04-20 JP JP2017083252A patent/JP2017165746A/ja active Pending
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