JP2014513121A5 - - Google Patents
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- Publication number
- JP2014513121A5 JP2014513121A5 JP2014509338A JP2014509338A JP2014513121A5 JP 2014513121 A5 JP2014513121 A5 JP 2014513121A5 JP 2014509338 A JP2014509338 A JP 2014509338A JP 2014509338 A JP2014509338 A JP 2014509338A JP 2014513121 A5 JP2014513121 A5 JP 2014513121A5
- Authority
- JP
- Japan
- Prior art keywords
- patient
- medicament according
- administered
- agent
- arterial hypertension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 102100025422 Bone morphogenetic protein receptor type-2 Human genes 0.000 claims 3
- 208000021124 Heritable pulmonary arterial hypertension Diseases 0.000 claims 3
- 101000934635 Homo sapiens Bone morphogenetic protein receptor type-2 Proteins 0.000 claims 3
- 230000035772 mutation Effects 0.000 claims 3
- 102000012085 Endoglin Human genes 0.000 claims 2
- 108010036395 Endoglin Proteins 0.000 claims 2
- 101100490437 Mus musculus Acvrl1 gene Proteins 0.000 claims 2
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 230000036772 blood pressure Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 210000001147 pulmonary artery Anatomy 0.000 claims 1
- 230000011664 signaling Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161481317P | 2011-05-02 | 2011-05-02 | |
| US61/481,317 | 2011-05-02 | ||
| PCT/US2012/035793 WO2012151153A1 (en) | 2011-05-02 | 2012-04-30 | Use of fk506 for the treatment of pulmonary arterial hypertension |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014513121A JP2014513121A (ja) | 2014-05-29 |
| JP2014513121A5 true JP2014513121A5 (cg-RX-API-DMAC7.html) | 2015-06-18 |
| JP6177765B2 JP6177765B2 (ja) | 2017-08-09 |
Family
ID=47108011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014509338A Active JP6177765B2 (ja) | 2011-05-02 | 2012-04-30 | 肺動脈性高血圧症の治療のためのｆｋ５０６の利用 |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US9474745B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP3821891B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6177765B2 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2012250974B9 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2834368C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1123900T1 (cg-RX-API-DMAC7.html) |
| DK (2) | DK2704711T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2856173T3 (cg-RX-API-DMAC7.html) |
| FI (1) | FI3821891T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20210245T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE053229T2 (cg-RX-API-DMAC7.html) |
| LT (1) | LT2704711T (cg-RX-API-DMAC7.html) |
| PL (1) | PL2704711T3 (cg-RX-API-DMAC7.html) |
| PT (2) | PT3821891T (cg-RX-API-DMAC7.html) |
| RS (1) | RS61480B1 (cg-RX-API-DMAC7.html) |
| SI (1) | SI2704711T1 (cg-RX-API-DMAC7.html) |
| SM (1) | SMT202100085T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012151153A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201307905B (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180325875A1 (en) * | 2015-01-13 | 2018-11-15 | Vivus, Inc. | Combination therapy for pulmonary hypertension |
| EP3294294A4 (en) * | 2015-05-08 | 2019-01-02 | Vivus, Inc. | Compositions and methods for the treatment or prevention of pulmonary hypertension |
| CN105062976B (zh) * | 2015-08-05 | 2018-05-11 | 中国医学科学院基础医学研究所 | 肺动脉高压治疗药物的干细胞筛选模型及应用 |
| ES2683921B1 (es) * | 2017-03-28 | 2019-04-22 | Univ Vigo | Método para la determinación del pronóstico en sujetos diagnosticados con hipertensión arterial pulmonar |
| US11413280B2 (en) | 2017-05-19 | 2022-08-16 | The Board Of Trustees Of The Leland Stanford Junior University | Enzastaurin and fragile histidine triad (FHIT)-increasing agents for the treatment of pulmonary hypertension |
| US12440479B2 (en) | 2018-03-28 | 2025-10-14 | Georg-August-Universitaet Goettingen, Stiftung Oeffentlichen Rechts, Universitaetsmedizin | Prevention or treatment of chronic organ injury |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6489335B2 (en) | 2000-02-18 | 2002-12-03 | Gholam A. Peyman | Treatment of ocular disease |
| US20050119330A1 (en) | 2003-03-17 | 2005-06-02 | Kao Peter N. | Use of antiproliferative agents in the treatment and prevention of pulmonary proliferative vascular diseases |
| WO2007112052A2 (en) | 2006-03-23 | 2007-10-04 | Macusight, Inc. | Formulations and methods for vascular permeability-related diseases or conditions |
| FR2936060B1 (fr) * | 2008-09-17 | 2010-11-19 | Assist Publ Hopitaux De Paris | Procede de diagnostic d'une sclerodermie systemique ou d'une hypertension arterielle pulmonaire. |
| MX2011004284A (es) * | 2008-10-22 | 2011-06-21 | Sam Amer & Co Inc | Metodo para tratar la hipertension arterial pulmonar. |
-
2012
- 2012-04-30 RS RS20210239A patent/RS61480B1/sr unknown
- 2012-04-30 HR HRP20210245TT patent/HRP20210245T1/hr unknown
- 2012-04-30 DK DK12779354.5T patent/DK2704711T3/da active
- 2012-04-30 SM SM20210085T patent/SMT202100085T1/it unknown
- 2012-04-30 DK DK20211109.2T patent/DK3821891T3/da active
- 2012-04-30 EP EP20211109.2A patent/EP3821891B1/en active Active
- 2012-04-30 ES ES12779354T patent/ES2856173T3/es active Active
- 2012-04-30 EP EP12779354.5A patent/EP2704711B1/en active Active
- 2012-04-30 SI SI201231881T patent/SI2704711T1/sl unknown
- 2012-04-30 FI FIEP20211109.2T patent/FI3821891T3/fi active
- 2012-04-30 PT PT202111092T patent/PT3821891T/pt unknown
- 2012-04-30 WO PCT/US2012/035793 patent/WO2012151153A1/en not_active Ceased
- 2012-04-30 HU HUE12779354A patent/HUE053229T2/hu unknown
- 2012-04-30 ES ES20211109T patent/ES2954905T3/es active Active
- 2012-04-30 CA CA2834368A patent/CA2834368C/en active Active
- 2012-04-30 LT LTEP12779354.5T patent/LT2704711T/lt unknown
- 2012-04-30 US US14/113,375 patent/US9474745B2/en active Active
- 2012-04-30 EP EP23177834.1A patent/EP4279130A3/en not_active Withdrawn
- 2012-04-30 JP JP2014509338A patent/JP6177765B2/ja active Active
- 2012-04-30 PT PT127793545T patent/PT2704711T/pt unknown
- 2012-04-30 PL PL12779354T patent/PL2704711T3/pl unknown
- 2012-04-30 AU AU2012250974A patent/AU2012250974B9/en active Active
-
2013
- 2013-10-23 ZA ZA2013/07905A patent/ZA201307905B/en unknown
-
2016
- 2016-09-21 US US15/271,794 patent/US20170007585A1/en not_active Abandoned
-
2017
- 2017-08-03 AU AU2017210583A patent/AU2017210583B2/en active Active
- 2017-10-12 US US15/782,153 patent/US20180185340A1/en not_active Abandoned
-
2018
- 2018-11-21 US US16/198,242 patent/US20190091208A1/en not_active Abandoned
-
2020
- 2020-07-29 US US16/941,778 patent/US20220184042A1/en not_active Abandoned
-
2021
- 2021-02-23 CY CY20211100151T patent/CY1123900T1/el unknown
-
2023
- 2023-01-06 US US18/151,028 patent/US20230404982A1/en active Pending
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