JP2014501750A5 - - Google Patents
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- Publication number
- JP2014501750A5 JP2014501750A5 JP2013545415A JP2013545415A JP2014501750A5 JP 2014501750 A5 JP2014501750 A5 JP 2014501750A5 JP 2013545415 A JP2013545415 A JP 2013545415A JP 2013545415 A JP2013545415 A JP 2013545415A JP 2014501750 A5 JP2014501750 A5 JP 2014501750A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- group
- formula
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 42
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 23
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 19
- 125000003118 aryl group Chemical group 0.000 claims 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 125000005843 halogen group Chemical group 0.000 claims 8
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 6
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 6
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 6
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims 5
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 4
- -1 cyclic acetal Chemical class 0.000 claims 4
- 239000012620 biological material Substances 0.000 claims 3
- 239000002537 cosmetic Substances 0.000 claims 3
- 229910052731 fluorine Chemical group 0.000 claims 3
- 125000001153 fluoro group Chemical group F* 0.000 claims 3
- 125000001072 heteroaryl group Chemical group 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 2
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 2
- 239000004473 Threonine Substances 0.000 claims 2
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 229940022399 cancer vaccine Drugs 0.000 claims 2
- 238000009566 cancer vaccine Methods 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 230000003712 anti-aging effect Effects 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 150000004676 glycans Polymers 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 230000003278 mimic effect Effects 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 150000004804 polysaccharides Polymers 0.000 claims 1
- 238000004321 preservation Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 150000003254 radicals Chemical class 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10306493.7 | 2010-12-22 | ||
| EP10306493 | 2010-12-22 | ||
| PCT/EP2011/073822 WO2012085221A1 (en) | 2010-12-22 | 2011-12-22 | Derivatives of glyco-cf2-serine and glyco-cf2-threonine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014501750A JP2014501750A (ja) | 2014-01-23 |
| JP2014501750A5 true JP2014501750A5 (https=) | 2015-02-19 |
| JP5934246B2 JP5934246B2 (ja) | 2016-06-15 |
Family
ID=43640126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013545415A Expired - Fee Related JP5934246B2 (ja) | 2010-12-22 | 2011-12-22 | グリコ−ｃｆ２−セリンおよびグリコ−ｃｆ２−トレオニンの誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9175044B2 (https=) |
| EP (1) | EP2655353B9 (https=) |
| JP (1) | JP5934246B2 (https=) |
| CN (1) | CN103328460B (https=) |
| BR (1) | BR112013015869A2 (https=) |
| CA (1) | CA2822097C (https=) |
| MX (1) | MX2013007292A (https=) |
| NZ (1) | NZ613333A (https=) |
| RU (1) | RU2013133788A (https=) |
| WO (1) | WO2012085221A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3530663B1 (en) * | 2013-01-14 | 2021-08-11 | Sunshine Biopharma Inc. | Process for preparing gem-difluorinated c-glycoside compounds |
| JP6629285B2 (ja) | 2014-03-17 | 2020-01-15 | テーエフケム | 生体材料及び微生物の保存及び保護のためのグリコペプチド誘導体 |
| CN117222655A (zh) | 2021-01-20 | 2023-12-12 | Tf化学公司 | 环状糖氨基酸衍生物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2842810B1 (fr) | 2002-07-25 | 2006-01-27 | Inst Nat Sciences Appliq | Nouveaux composes gem difluores, leur procedes de preparation et leurs applications. |
| GB0224799D0 (en) * | 2002-10-25 | 2002-12-04 | Amersham Plc | Improved complex compositions |
| FR2878851B1 (fr) | 2004-12-02 | 2007-02-09 | Inst Nat Sciences Appliq | Composes c-glycopeptides gem-difluores, leur preparation et leur utilisation en cryochirurgie et/ou cryopreservation |
| FR2900154B1 (fr) | 2006-04-25 | 2008-07-04 | Inst Nat Sciences Appliq | Nouveaux composes c-glycosides gem-difluores derives de la podophyllotoxine, leur preparation et leurs applications. |
| FR2900656A1 (fr) * | 2006-05-03 | 2007-11-09 | Inst Nat Sciences Appliq | Composes c-glycopeptides gem-difluores, leur preparation et leur utilisation notamment pour la preservation de materiaux biologiques |
-
2011
- 2011-12-22 NZ NZ613333A patent/NZ613333A/en not_active IP Right Cessation
- 2011-12-22 US US13/823,237 patent/US9175044B2/en active Active
- 2011-12-22 WO PCT/EP2011/073822 patent/WO2012085221A1/en not_active Ceased
- 2011-12-22 CN CN201180062006.6A patent/CN103328460B/zh not_active Expired - Fee Related
- 2011-12-22 BR BR112013015869A patent/BR112013015869A2/pt not_active IP Right Cessation
- 2011-12-22 MX MX2013007292A patent/MX2013007292A/es unknown
- 2011-12-22 RU RU2013133788/04A patent/RU2013133788A/ru unknown
- 2011-12-22 EP EP11805036.8A patent/EP2655353B9/en not_active Not-in-force
- 2011-12-22 CA CA2822097A patent/CA2822097C/en active Active
- 2011-12-22 JP JP2013545415A patent/JP5934246B2/ja not_active Expired - Fee Related
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