JP2014500307A5 - - Google Patents

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JP2014500307A5
JP2014500307A5 JP2013545584A JP2013545584A JP2014500307A5 JP 2014500307 A5 JP2014500307 A5 JP 2014500307A5 JP 2013545584 A JP2013545584 A JP 2013545584A JP 2013545584 A JP2013545584 A JP 2013545584A JP 2014500307 A5 JP2014500307 A5 JP 2014500307A5
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agent
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JP2013545584A
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Japanese (ja)
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JP2014500307A (ja
JP5992435B2 (ja
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Priority claimed from PCT/IB2011/055730 external-priority patent/WO2012085789A1/en
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Publication of JP2014500307A5 publication Critical patent/JP2014500307A5/ja
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JP2013545584A 2010-12-21 2011-12-16 循環からの生体分子の除去剤 Active JP5992435B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10196092.0 2010-12-21
EP10196092 2010-12-21
PCT/IB2011/055730 WO2012085789A1 (en) 2010-12-21 2011-12-16 Agents for clearing biomolecules from circulation

Publications (3)

Publication Number Publication Date
JP2014500307A JP2014500307A (ja) 2014-01-09
JP2014500307A5 true JP2014500307A5 (https=) 2015-10-29
JP5992435B2 JP5992435B2 (ja) 2016-09-14

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ID=43530614

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JP2013545584A Active JP5992435B2 (ja) 2010-12-21 2011-12-16 循環からの生体分子の除去剤

Country Status (6)

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US (1) US9427482B2 (https=)
EP (1) EP2654796A1 (https=)
JP (1) JP5992435B2 (https=)
CN (1) CN103328008B (https=)
RU (1) RU2013133813A (https=)
WO (1) WO2012085789A1 (https=)

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WO2014081300A1 (en) * 2012-11-22 2014-05-30 Tagworks Pharmaceuticals B.V. Channel protein activatable liposomes
US20150297741A1 (en) * 2012-11-22 2015-10-22 Tagworks Pharmaceuticals B.V. Bio-orthogonal drug activation
WO2014081299A1 (en) * 2012-11-22 2014-05-30 Tagworks Pharmaceuticals B.V. Activatable liposomes
WO2014081303A1 (en) * 2012-11-22 2014-05-30 Tagworks Pharmaceuticals B.V. Chemically cleavable group
US10130711B2 (en) 2013-06-19 2018-11-20 The Regents Of The University Of California Chemical structures for localized delivery of therapeutic agents
ES2880468T3 (es) 2014-03-14 2021-11-24 Univ California Conjugados de TCO y métodos para el suministro de agentes terapéuticos
WO2016025480A1 (en) 2014-08-11 2016-02-18 The General Hospital Corporation Cyclooctenes for bioorthogonol reactions
LT3319959T (lt) 2015-07-06 2021-12-27 Alkermes, Inc. Histono deacetilazės hetero-halogeno inhibitoriai
EP3319968A1 (en) 2015-07-06 2018-05-16 Rodin Therapeutics, Inc. Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
JP6823067B2 (ja) 2015-09-10 2021-01-27 タンボ・インコーポレイテッド 生体直交型組成物
US11617799B2 (en) 2016-06-27 2023-04-04 Tagworks Pharmaceuticals B.V. Cleavable tetrazine used in bio-orthogonal drug activation
US10222346B2 (en) * 2017-01-09 2019-03-05 National Research Council Of Canada Decomposable S-tetrazine based polymers for single walled carbon nanotube applications
RS62959B1 (sr) 2017-01-11 2022-03-31 Alkermes Inc Biciklični inhibitori histon-deacetilaze
ES2983582T3 (es) 2017-04-07 2024-10-23 Tambo Inc Composiciones bioortogonales
US11565005B2 (en) 2017-07-06 2023-01-31 Memorial Sloan Kettering Cancer Center Dota-hapten compositions for anti-dota/anti-tumor antigen bispecific antibody pretargeted radioimmunotherapy
WO2019014549A1 (en) 2017-07-14 2019-01-17 The Penn State Research Foundation Compositions and methods for targeted delivery of therapeutic and/or diagnostic species
US11225475B2 (en) 2017-08-07 2022-01-18 Alkermes, Inc. Substituted pyridines as inhibitors of histone deacetylase
CA3093694A1 (en) 2018-03-12 2019-09-19 Memorial Sloan Kettering Cancer Center Bispecific binding agents and uses thereof
JP7542538B2 (ja) 2018-09-18 2024-08-30 ニカング セラピューティクス, インコーポレイテッド Srcホモロジー-2ホスファターゼ阻害剤としての縮合三環式環誘導体
WO2020247151A1 (en) * 2019-06-05 2020-12-10 Boston Scientific Scimed, Inc. Click chemistry capturable platinum-based antineoplastic agents
JP7660525B2 (ja) 2019-06-17 2025-04-11 タグワークス ファーマシューティカルス ビー.ブイ. イン・ビボで生体分子から標識を切断する為の剤
EP4382129A3 (en) 2019-06-17 2024-07-03 Tagworks Pharmaceuticals B.V. Compounds for fast and efficient click release
EP4295917A3 (en) 2020-08-07 2024-02-28 Tambo, Inc. Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
IL322729A (en) * 2023-02-15 2025-10-01 Tagworks Pharmaceuticals B V Tetrazines with improved properties
US20250243238A1 (en) * 2024-01-31 2025-07-31 Oregon State University Tetrazine amino acids and methods for their production and use

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EP2419142B1 (en) * 2009-04-16 2020-01-15 Tagworks Pharmaceuticals B.V. Pretargeting kit, method and agents used therein
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KR20140038348A (ko) 2010-12-13 2014-03-28 바이오미메틱 세라퓨틱스, 엘엘씨 척추 유합 절차를 위한 조성물 및 방법

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