JP2014171571A - Fluid injection apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To appropriately control a discharge rate in accordance with a temperature since there is a tube whose hardness and elasticity vary depending on a change of the temperature among the tubes used for a pump, and the discharge rate changes in making a fluid flow by squeezing the tube.SOLUTION: A fluid injection apparatus includes: a tube 225 in which a fluid can flow; a pump for sending the fluid by pressing the tube; a temperature measuring part 420 for measuring a temperature of a peripheral edge of the tube; and a control part which controls an amount of driving for the pump in accordance with the measured temperature.

Description

  The present invention relates to a fluid injection device.

  An insulin pump for injecting insulin into a living body has been put into practical use. A fluid injection device such as an insulin pump is fixed to a living body such as a human body, and regularly injects fluid into a living body such as a human body according to a preset program.

  Patent Document 1 discloses a form in which a flexible tube is sequentially pushed with fingers.

JP-T-2001-515557

  Some tubes used in pumps vary in hardness and elasticity due to temperature changes. If the temperature is lowered and the elasticity of the tube is lowered, the restoring speed of the deformed tube is reduced. When the fluid is made to flow by squeezing the tube, it is considered that the discharge amount is lowered because the next squeezing is performed in a state where the amount of liquid in the tube is reduced when the restoration speed becomes slow. Therefore, it is desired to appropriately control the discharge amount according to the temperature.

  The present invention has been made in view of such circumstances, and an object thereof is to appropriately control the discharge amount in accordance with the temperature.

The main invention for achieving the above object is:
A tube through which fluid can flow;
A pump for feeding the fluid by pressing the tube;
A temperature measuring unit for measuring the temperature of the periphery of the tube;
A control unit for controlling the driving amount of the pump according to the measured temperature;
Is a fluid injection device.

  Other features of the present invention will become apparent from the description of the present specification and the accompanying drawings.

1 is an overall perspective view of a micropump 1. FIG. 2 is a separation view of the micropump 1. 2 is a permeation top view of the micropump 1. FIG. 1 is a cross-sectional view of a micropump 1. 2 is an internal perspective view of a main body 10. FIG. 3 is a rear perspective view of the main body 10. FIG. FIG. 4 is an exploded perspective view of the cartridge 20. 4 is a rear perspective view of the cartridge base 210. FIG. 2 is a rear perspective view of the micropump 1. FIG. 1 is a block diagram of a micro pump 1. FIG. It is a flowchart in a 1st embodiment. It is a graph which shows the relationship between temperature and a drive amount. 13A is an explanatory diagram of positions where the first electrode and the second electrode 424 are disposed in the second embodiment, FIG. 13B is a cross-sectional view taken along the line CC in FIG. 13A, and FIG. 13C is a tube 225. It is a partial top view and a partial bottom view. It is a circuit diagram of the composite detection part 420 in 2nd Embodiment. 15A is a diagram illustrating a voltage input to the input terminal A, FIG. 15B is a diagram illustrating a voltage output from the output terminal B1, and FIG. 15C illustrates a voltage output from the output terminal B2. FIG. It is explanatory drawing of the other shape of the 1st electrode 422. FIG.

At least the following matters will become clear from the description of the present specification and the accompanying drawings. That is,
A tube through which fluid can flow;
A pump for feeding the fluid by pressing the tube;
A temperature measuring unit for measuring the temperature of the periphery of the tube;
A control unit for controlling the driving amount of the pump according to the measured temperature;
Is a fluid injection device.
If the tube hardens due to temperature changes, the tube's restoration speed slows down, so it may not be possible to obtain the expected discharge amount even if the tube is pressed. Since it can be controlled, the discharge amount can be appropriately controlled according to the temperature.

In such a fluid injection device, it is preferable that the pump includes a plurality of fingers that sequentially push the tube.
Thus, in the case of a pump of a type in which a plurality of fingers push the tube sequentially, a delay in the restoring speed of the tube due to a temperature change becomes a problem, but the driving amount of the pump can be controlled based on the temperature. Therefore, the discharge amount can be appropriately controlled according to the temperature.

The material of the tube is desirably one of a styrene thermoplastic elastomer and an olefin thermoplastic elastomer.
These elastomers are rubber-elastic materials, but even if the tube hardness changes due to a temperature drop, the pump drive amount can be controlled based on the temperature. The discharge amount can be controlled appropriately.

The control unit drives the pump with a first drive amount when the temperature is the first temperature, and is greater than the first drive amount when the temperature is lower than the first temperature. It is desirable to drive the pump with a high driving amount.
By doing so, the drive amount can be increased in the case where the temperature is considered to be low and the tube is cured, so that the decrease in the discharge amount due to the delay in the restoration speed of the tube can be compensated by the drive amount.

The temperature measurement unit preferably includes an electrical resistance member that is in close contact with the tube.
By doing in this way, the temperature relevant to a tube can be measured more reliably.

In addition, the temperature measurement unit is a first electrode whose electrical resistance changes with a temperature related to the tube, and the first electrode provided on a part of the circumference of the tube, and the first electrode together with the first electrode. A second electrode at a position facing the first electrode with the tube interposed therebetween, and measuring a temperature associated with the tube based on a change in electrical resistance of the first electrode; and the first electrode and the first electrode It is desirable to determine whether or not bubbles are mixed in the tube based on the change in capacitance between the two electrodes.
By doing in this way, while being able to measure the temperature of a tube based on the change of the electrical resistance of a 1st electrode, it can be determined whether the bubble is mixed in the tube.

The first electrode is preferably formed such that one resistance wire is bent and a plurality of the resistance wires are arranged in parallel.
By doing in this way, while the length of the resistance line which occupies per unit area can be lengthened, a capacitor can be comprised with a 2nd electrode.

The second electrode is preferably a plate-like member.
By doing so, it is possible to reliably grasp the change in capacitance and determine whether or not bubbles are mixed in the tube.

=== Embodiment ===
FIG. 1 is an overall perspective view of the micropump 1. FIG. 2 is a separation view of the micropump 1. The micropump 1 includes a main body 10, a cartridge 20, and a patch 30. These three bodies are separable as shown in FIG. 2, but are assembled as a unit as shown in FIG. As an example, the micropump 1 is attached to a living body and is suitably used for regular infusion of insulin.

  FIG. 3 is a transparent top view of the micropump 1. FIG. 4 is a cross-sectional view of the micropump 1. That is, FIGS. 3 and 4 are views when the main body 10, the cartridge 20, and the patch 30 are assembled. FIG. 5 is an internal perspective view of the main body 10. FIG. 6 is a rear perspective view of the main body 10. FIG. 6 is a diagram illustrating the back surface of FIG. 5 described above. FIG. 7 is an exploded perspective view of the cartridge 20. FIG. 8 is a rear perspective view of the cartridge base 210. FIG. 9 is a rear perspective view of the micropump 1.

  Hereinafter, each part of the micropump 1 will be described with reference to FIGS. 1 to 9. First, each part in the main body 10 will be described.

  As shown in FIG. 5, the main body 10 includes a main body base 110, each part configured on the main body base 110, and a main body case 130. Each part on the main body base 110 is covered and protected by the main body case 130.

  The main body 10 includes a circuit board 140 configured on the main body base 110. The circuit board 140 is an electronic board for controlling the piezoelectric motor 150 and the like according to a program or the like. The main body includes a piezoelectric motor 150. The piezoelectric motor 150 is a motor for applying a rotational driving force to the cam 121 described later.

  The piezoelectric motor 150 includes a plate-shaped member 151 and a pair of springs 152 (FIG. 3). The spring 152 urges the plate member 151 toward the rotor wheel 128 by its elastic force. The plate-like member 151 is urged toward the rotor wheel 128 as described above, and the front end portion thereof contacts the circumferential surface of the rotor wheel 128.

  The plate-like member 151 is a member configured in a layer shape. The plate-shaped member 151 includes a piezoelectric layer and two electrodes, and changes its shape by changing the voltage applied to these two electrodes. For example, longitudinal vibration and bending vibration are alternately repeated according to the applied voltage. The longitudinal vibration changes the length of the plate-shaped member 151 in the axial direction, and the bending vibration changes the plate-shaped member into a substantially S-shape. By repeating these alternately, the rotor wheel 128 is rotated in a predetermined direction.

  The rotor wheel 128 has a pinion that rotates integrally at different positions with respect to the height direction of the micropump 1, and this pinion engages with the gear of the intermediate wheel 127 and rotates the intermediate wheel 127. The intermediate wheel 127 also has a pinion that rotates integrally at different positions with respect to the height direction of the micropump, and this pinion engages with a gear that rotates integrally with the output shaft 126. The rotor wheel 128, the intermediate wheel 127, and the output shaft 126 are rotatably fixed to individual shafts by a train wheel bridge 125 fixed to the main body 10 (FIG. 5).

  The cam 121 is also fixed to the output shaft 126 pivotally supported by the bearing 129 so as to be integrally rotatable. Then, the cam 121 is also rotated along with the rotation of the output shaft 126. Thereby, the motive power from the piezoelectric motor 150 is transmitted to the cam 121 (FIG. 4).

  As shown in FIG. 6, a hook hook 171 is provided in front of the main body 10, and two hook insertion openings 172 are provided in the rear. The fixing hook 271 of the cartridge 20 is engaged with the hook hook 171, and the fixing hook 272 is engaged with the hook insertion port 172, whereby the cartridge 20 can be fixed to the main body 10 (FIGS. 2 and 4).

  At this time, since the packing 273 is fitted in the groove on the outer periphery of the upper surface of the cartridge base 210, when the main body 10 and the cartridge 20 are fixed, the cartridge 10 is sealed so that liquid or the like does not enter the space formed by these. can do.

  Further, the main body 10 includes a secondary battery storage unit 180 on the back surface (FIG. 6). The secondary battery storage unit 180 includes a battery positive terminal 182 and a battery negative terminal 183. By inserting the secondary battery 181 into the secondary battery storage unit, predetermined power can be supplied to each part of the main body 10. To do.

Next, the cartridge 20 will be described.
As shown in FIG. 7, the cartridge 20 includes a cartridge base 210, a cartridge base presser 240, and each part configured on the cartridge base. As will be described later, the cartridge base 210 constitutes a reservoir 290 together with the reservoir film 250.

  The cartridge base 210 of the cartridge 20 includes a finger unit 220 on the upper surface thereof. The finger unit 220 includes a finger base 227, fingers 222, a tube 225, and finger pressers 226. Further, on the upper surface of the cartridge base 210, a suction connector 228 and a discharge connector 229 are provided. The suction connector 228 is a connector 228 for sucking liquid into the finger unit 220, and the discharge connector 229 is a connector for discharging liquid from the finger unit 220.

  A plurality of grooves are formed in the finger base 227, and a suction connector 228 and a discharge connector 229 are inserted into these grooves. Further, the finger base 227 is formed with a tube guide groove 227 a for guiding the tube 225 in an arc shape, and accommodates the tube 225. One end of the tube 225 is tightly connected to the suction connector 228, and the other end is tightly connected to the discharge connector 229.

  As the material of the tube 225, a styrene thermoplastic elastomer or an olefin thermoplastic elastomer is employed. These elastomers have rubber elasticity and are excellent in sealing properties and recoverability. Moreover, since it is thermoplastic, it can be molded using a general-purpose thermoplastic resin molding machine.

  A plurality of finger guides 227b are formed inside the arc of the tube guide groove 227a. Each of the finger guides 227 b accommodates the fingers 222. As a result, the tips 222 a of the fingers 222 are arranged so as to be substantially perpendicular to the tube 225.

  A finger presser 226 is fixed to the upper surface of the finger base 227 by a fixing screw (not shown). As a result, the finger 222 can slide and move only in the direction along the finger guide 227b.

  As described above, since the finger 222 and the tube 225 are provided on the cartridge 20 side, even if the tube 225 has a different diameter, the finger 222 having a length corresponding to the tube diameter is used. Can be provided. Accordingly, even if the cam 121 has a standardized size, the cam surface 121a of the cam 121 can be appropriately arranged at a position where it abuts against the rear end portion 222b of the finger 222 (FIG. 4).

  A patch connection needle 231 is provided on the side surface of the cartridge base 210 to allow liquid to be sent to the patch 30 via the patch septum 350. The patch connection needle 231 communicates with the discharge connector 229. On the other hand, the suction connector 228 communicates with a storage portion 290 to be described later via a through hole provided in the cartridge base 210. As a result, the liquid in the reservoir 290 can be supplied to the patch connection needle 231 through the suction connector 228, the tube 225, and the discharge connector 229 (FIG. 7).

  As shown in FIG. 4, the cartridge 20 includes a reservoir film 250. The periphery of the reservoir film 250 is sandwiched between the cartridge base 210 and the film pressing portion 242 provided in the cartridge base pressing member 240. As a result, a reservoir 290 can be formed between the reservoir film 250 and the cartridge base 210, and liquid can be stored in the reservoir 290.

  The reservoir film 250 may be fixed to the cartridge base 210 by welding, and the cartridge base holder 240 and the cartridge base 210 may be fixed.

  The cartridge base 210 is made of plastic, and the surface on which the reservoir film 250 is provided has a curved shape as shown in FIG. Thus, although the storage part 290 has a curved surface shape, since the film of the reservoir film 250 can be deformed according to the remaining amount of the liquid stored in the storage part 290, the fluid is stored in the storage part 290. It can be squeezed out so as not to remain. Further, at this time, it is desirable that the reservoir film 250 is processed into a curved surface in a shape along the curved surface shape. By doing in this way, even if the fluid in the storage part 290 decreases, the reservoir film 250 is deformed along the curved surface, so that the liquid can be squeezed out without remaining.

  The reservoir film 250 is composed of a multilayer film. At this time, the inner layer is preferably polypropylene, and the outer layer is preferably selected from a material having excellent gas barrier properties. The reservoir film 250 is not limited to this, and may be, for example, a thermoplastic elastomer or a film in which another material is bonded to the thermoplastic elastomer.

  Further, a cartridge septum 280 is provided on the lower surface side of the cartridge 20 (FIG. 9). The cartridge septum 280 is inserted into the cartridge septum insertion hole 241 provided in the cartridge base retainer 240 when the cartridge base 210 and the cartridge base retainer 240 are assembled. One surface of the cartridge septum 280 is exposed to the patch base 340 and the openings 340 a and 360 a of the adhesive tape 360 (FIGS. 2 and 9), and the other surface communicates with the fluid inlet 211. As shown in FIG. 8, the fluid inflow port 211 opens between the reservoir film 250 and the cartridge base 210. Therefore, the liquid injected by the injection needle or the like through the cartridge septum 280 is stored in the storage unit 290.

Next, the patch 30 will be described mainly with reference to FIG.
The patch 30 includes a catheter 310, an introduction needle 320, an introduction needle folder 321, an introduction needle septum 322, a port base 330, a patch base 340, a patch septum 350, and an adhesive tape 360.

  The patch septum 350 is for supplying a liquid into the patch 30 by inserting a patch connection needle 231 as will be described later. The patch septum 350 is provided on the side wall portion of the patch 30, whereby the patch connection needle 231 penetrates the patch septum 350 when the reservoir 20 is mounted toward the side surface of the patch 30.

  Note that the septum such as the patch septum 350 is formed of a material (for example, silicone rubber, isoprene rubber, butyl rubber, or the like) that closes a hole that is opened by penetrating a needle or the like. Thereby, even if the needle is inserted into and removed from the septum, liquid or the like does not leak through the septum.

  The catheter 310 is a tube for injecting liquid. A part of the catheter 310 is held by the port base 330, and a part is exposed to the lower side of the port base 330. When liquid is injected using the patch 30, the exposed portion of the catheter 310 is placed inside the living body and the liquid is continuously injected. Therefore, the catheter 310 is formed of a soft material such as a fluororesin or a polyurethane resin that is excellent in biocompatibility.

  The introduction needle 320 is a hollow elongated needle-like member, and the outer shape thereof is smaller than the inner diameter of the catheter 310. The introduction needle 320 is inserted into the catheter 320 before use. The sharp end side of the introduction needle 320 is exposed in the lower direction of the catheter 310, and the other end side is fixed to the introduction needle folder 321. Further, before use, the introduction needle 320 is inserted through an introduction needle septum 322 fixed in the port base 330.

  With such a configuration, when the introduction needle folder 321 is pulled out from the port base 330, the introduction needle 320 is pulled out from the catheter 310, but the liquid flowing in from the patch connection needle 231 does not leak from the introduction needle septum 322 side, It flows into the living body through the catheter 310.

  As shown in FIG. 2, the patch 30 includes a patch base 340. The patch base 340 is fixed to the port base 330 and includes a cartridge fixing member 341, so that the cartridge 20 can be fixed to the patch 30. When the cartridge 20 is connected to the patch 30, the cartridge 20 is slid from the left side of FIG. Then, the patch connection needle 231 provided in the cartridge 20 passes through the patch septum 350 and is inserted into the patch 30.

  The patch base 340 includes an adhesive tape 360 on the lower surface. Then, the micropump 1 can be attached to a living body or the like.

  When the main body 10 and the cartridge 20 are assembled, the cam 121 of the main body 10 is inserted into the cam accommodating portion 227c of the finger base 227 as shown in FIG. Thereby, the cam surface 121a of the cam 121 is disposed at a position facing the rear end portion 222b of the finger 222. Then, the cam surface 121 a comes into contact with the rear end portion 222 b of the finger 222 by the rotation of the cam 121, and the finger 222 can be slid.

  As shown in FIG. 4, the micropump 1 includes a temperature sensor 410. This temperature sensor 410 acquires the temperature of the storage part in the micropump 1. Since the liquid in the reservoir passes through the tube 225 and changes the tube 225 to the temperature of the liquid, the temperature sensor 410 will acquire the temperature associated with the tube 225. That is, the temperature related to the tube 225 is, for example, the temperature in the vicinity of the peripheral surface of the tube 225, that is, the peripheral edge of the tube 225.

  FIG. 10 is a block diagram of the micropump 1. FIG. 10 shows a controller 141, a piezoelectric motor 150 connected to the controller 141, and a detector group 400. The detector group 400 includes the temperature sensor 410 (first embodiment) or the composite detection unit 420 (second embodiment) described above. The controller 141 includes a CPU 141a and a memory 141b. The memory 141b stores the driving amount of the piezoelectric motor 150 with respect to the measured temperature, as will be described later. The controller 141 controls the piezoelectric motor 150 in accordance with a program and a signal from the detector group 400.

  FIG. 11 is a flowchart in the first embodiment. FIG. 12 is a graph showing the relationship between temperature and drive amount. Hereinafter, priming control in the first embodiment will be described with reference to these drawings.

  In the first embodiment, the temperature of the tube 225 is not directly measured, but the temperature related to the tube 225 is acquired by the temperature of the temperature sensor 410 described above. This is because since the micropump 1 itself is small, the temperature is considered to be substantially the same regardless of the portion.

  Therefore, the temperature is measured by the temperature sensor 410 (S102). Then, the driving amount corresponding to the temperature sensor is searched in view of the profile stored in the memory 141b (S104). FIG. 12 shows the relationship (profile) between temperature and drive amount. As shown in FIG. 12, the driving amount is lower as the measured temperature is higher, and the driving amount is higher as the measured temperature is lower.

  This is because the hardness of the tube 225 varies with temperature in the micropump 1 described above. When the temperature is high, the tube 225 is relatively soft, so even if the tube 225 is pushed by the finger 222, the tube 225 is immediately restored to its original shape by its elastic force. On the other hand, when the temperature is low, since the tube 225 is hard, even if the finger 222 is separated from the tube 225 after being pushed by the finger 222, the tube 225 is difficult to return to its original shape due to its elastic force.

  Therefore, when the finger 222 pushes the tube 225 by the next cam crest, the tube 225 may not yet return to the original shape. If it does so, the liquid amount in the tube 225 in the location pressed by the finger 222 will also reduce. Therefore, even if the tube 225 is sequentially pushed by the finger 222, the discharge amount is reduced.

  For this reason, here, when the temperature is low, the drive amount of the piezoelectric motor 150 is increased to compensate for the decrease in the discharge amount.

  When the drive amount is searched in light of the profile in the memory 141b, the piezoelectric motor 150 is driven with this drive amount. By doing in this way, discharge amount can be controlled appropriately according to temperature.

  By the way, in 1st Embodiment, although the temperature sensor 410 with which the inside of the micropump 1 was equipped was utilized, as shown in 2nd Embodiment below, it contacts the tube 225 directly and acquires the temperature. It is good as well.

  FIG. 13A is an explanatory diagram of positions where the first electrode 422 and the second electrode 424 are disposed in the second embodiment. 13B is a cross-sectional view taken along the line CC in FIG. 13A. FIG. 13C is a partial top view and a partial bottom view of the tube 225. FIG. 13A shows a tube 225, a cam 121, a plurality of fingers 222, a suction connector 228, and a discharge connector 229, as in the first embodiment.

  In the second embodiment, the first electrode 422 and the second electrode 424 are provided on the downstream side of the finger 222. This is because air bubbles may be generated everywhere in the tube 225. Thus, by providing the first electrode 422 and the second electrode 424 on the downstream side of the finger 222, the tube 225 has a wider range. This is because the generated bubbles can be detected on the downstream side.

  The first electrode 422 and the second electrode 424 are provided at positions facing each other with the tube 225 interposed therebetween. Thereby, as will be described later, not only the temperature of the fluid in the tube 225 is measured, but also the bubbles generated in the tube 225 can be detected.

  The first electrode 422 is in close contact with the tube 225, and the temperature of the first electrode 422 also changes according to the temperature of the fluid in the tube 225. As shown in FIG. 13C, the first electrode 422 is formed such that one resistance wire is bent and a plurality of parallel lines are aligned in the longitudinal direction of the tube 225, and is attached to the upper surface side of the tube 225. By doing in this way, the electrical resistance of the 1st electrode 422 changes according to the temperature of the fluid in the tube 225. On the other hand, the second electrode 424 is a plate-like member as shown in FIG. 13C and is provided in contact with the lower surface of the tube 225. In this way, the first electrode 422 and the second electrode 424 constitute a capacitor. And it is supposed that the change of the electrostatic capacitance by the change of the fluid in a tube will be caught.

  FIG. 14 is a circuit diagram of the composite detection unit 420 in the second embodiment. FIG. 14 shows a cross section of the tube 225, a first electrode 422 attached to the upper surface of the tube 225, and a second electrode 424 provided on the lower surface of the tube 225. One end of the first electrode 422 is an input end A. The input terminal A is connected to the controller 141. In addition, a resistor R4 and a capacitor C1 are connected in parallel to the other end of the first electrode 422, and the other end is grounded. The other end of the first electrode 422 has an output end B1.

  The second electrode 424 is connected to the resistor R3 and the anode of the diode D. The other end of the resistor R3 is grounded. The cathode of the diode D constitutes the output terminal B2. A capacitor C2 is connected in parallel to the output terminal B2. The other end of the capacitor C2 is grounded. The output terminal B1 and the output terminal B2 are also connected to the controller 141. That is, the composite detection unit 420 is configured by the circuit in FIG. 14 and the controller 141.

  FIG. 15A is a diagram illustrating a voltage input to the input terminal A. FIG. FIG. 15B is a diagram illustrating a voltage output from the output terminal B1. FIG. 15C is a diagram illustrating a voltage output from the output terminal B2.

  An AC voltage having a reference voltage E1 and an amplitude α is applied to the input terminal A as shown in FIG. 15A. In the circuit shown in FIG. 14, a resistor R4 and a capacitor C1 constitute a low pass filter. Therefore, the AC component is removed by the low-pass filter, and a DC component as shown in FIG. 15B is output from the output terminal B1. Here, the voltage value V1 output from the output terminal B1 can be obtained by V1 = E1 × R1 / R4. Here, the resistance R <b> 1 is the resistance value of the first electrode 422.

  When a temperature rise occurs in the fluid in the tube 225, the temperature of the first electrode 422 also rises and the resistance value of the first electrode 422 becomes R1 + ΔR. Therefore, the voltage V1 output from the output terminal B1 is V1 = E1 × (R1 + ΔR) / R4. That is, when the temperature of the fluid rises, the voltage value output from the output terminal B1 increases.

  The controller 141 obtains the temperature of the fluid in the tube 225 based on the relationship between the voltage V and the temperature obtained in advance. By doing in this way, the temperature of the fluid in the tube 225 can be measured cheaply and simply.

  When the temperature is measured in this way, the driving amount of the piezoelectric motor 150 corresponding to the temperature is obtained as in the first embodiment. Then, the piezoelectric motor 150 is driven according to this driving amount. By doing in this way, discharge amount can be controlled appropriately according to temperature.

  On the other hand, a direct current component as shown in FIG. 15C is output from the output terminal B2. In addition, what is shown with the broken line in FIG. 15C is the output at B3 in FIG. As described above, the capacitor is configured by sandwiching the tube 225 between the first electrode 422 and the second electrode 424. At this time, a fluid such as a chemical solution is flowing in the tube 225 without bubbles and the like being mixed therein.

  It is assumed that the output at B3 at this time is a voltage indicated by a broken line in FIG. 15C. The direct current component output by half-wave rectification by the diode D and the capacitor C2 is the output at B2.

  In such a configuration, if bubbles are mixed into the tube 225, the capacitance between the first electrode 422 and the second electrode 424 changes, so the amplitude at B3 (β in FIG. 15C) changes. Therefore, the voltage at the output terminal B2 that is output after being half-wave rectified also varies.

  The controller 141 determines that air bubbles are mixed in the tube 225 when the absolute value of the fluctuation amount of the voltage output from the output terminal B2 exceeds a predetermined value. In this way, not only can the clogging in the tube 225 be detected, but also the presence or absence of bubbles mixed in the tube 225 can be determined.

  Here, the presence / absence of bubbles mixed in the tube 225 is determined based on the voltage at the output terminal B2, but if the capacitance of the capacitor formed by the first electrode 422 and the second electrode 242 changes, B3 A change also occurs in the phase difference of the alternating current detected at δ (δ in FIG. 15C). Therefore, it is good also as determining the presence or absence of the bubble mixed in the tube 225 based on the change of the phase difference of the alternating current detected in B3.

  When bubbles are mixed in the tube 225, the discharge amount of the liquid is reduced by the amount of bubbles. Therefore, when it is determined that bubbles are mixed, the driving force may be obtained by searching for a profile different from the above-described profile. That is, it is possible to search for a profile that provides a higher driving force. In addition, when it is determined that bubbles are mixed in the tube 225, a process for discharging the bubbles may be performed.

  FIG. 16 is an explanatory diagram of another shape of the first electrode 422. In the second embodiment, the first electrode has been described as a shape in which one resistance wire is bent and a plurality of parallel lines are arranged in the longitudinal direction of the tube 225. As shown in FIG. It is good also as a shape shape | molded so that a some parallel line may line up in the direction which cross | intersects the longitudinal direction of the tube 225. FIG.

  Further, when the bubble detection is not performed, an electric resistance wire wound in the circumferential direction of the tube 225 may be used. By doing in this way, since a resistance wire can be stuck to the circumference of tube 225, a resistance wire can acquire a temperature change of a tube appropriately.

=== Other Embodiments ===
The above-described micropump 1 can be reduced in size and thickness, and can stably flow continuously at a minute flow rate. Therefore, the micropump 1 can be attached to a living body or on the surface of a living body to develop a new drug or perform drug delivery. Suitable for use. Moreover, in various mechanical devices, it can be mounted in the device or outside the device and used for transporting fluids such as water, saline, chemicals, oils, fragrances, inks and gases. Further, the micropump alone can be used for fluid flow and supply.

  The above-described embodiments are for facilitating the understanding of the present invention, and are not intended to limit the present invention. The present invention can be changed and improved without departing from the gist thereof, and it is needless to say that the present invention includes equivalents thereof.

  The above-described embodiments are for facilitating the understanding of the present invention, and are not intended to limit the present invention. The present invention can be changed and improved without departing from the gist thereof, and it is needless to say that the present invention includes equivalents thereof.

1 Micro pump 10 body, 20 cartridge,
30 patches,
110 body base,
121 cam, 121a cam surface,
125 wheel train, 126 output shaft, 127 intermediate wheel,
128 rotor cars, 129 bearings,
130 body case, 140 circuit board, 141 controller,
150 piezoelectric motor, 151 plate member, 152 spring,
171 hook hook, 172 hook insertion slot,
180 Secondary battery compartment, 181 Secondary battery,
182 battery positive terminal, 183 battery negative terminal,
210 cartridge base, 211 fluid inlet,
220 finger units,
222 fingers, 222a front end, 222b rear end,
225 tube, 226 finger press,
227 finger base,
227a tube guide groove, 227b finger guide, 227c cam housing,
228 Connector for suction, 229 Connector for discharge,
231 patch connecting needle,
240 Cartridge base holder,
241 Cartridge septum insertion hole, 242 Film holding part,
250 reservoir film,
271 fixed hook, 272 fixed hook, 273 packing,
280 cartridge septum, 290 reservoir,
310 catheter, 320 introduction needle, 321 introduction needle folder,
322 Introducing septum,
330 port base, 340 patch base, 340a opening,
341 cartridge fixing member,
350 patch septum, 360 adhesive tape, 360a opening,
400 detector groups, 410 temperature sensors,
420 composite detection unit, 422 first electrode, 424 second electrode,
426 Other shapes of the first electrode

Claims (8)

A tube through which fluid can flow;
A pump for feeding the fluid by pressing the tube;
A temperature measuring unit for measuring the temperature of the periphery of the tube;
A control unit for controlling the driving amount of the pump according to the measured temperature;
A fluid injection device comprising: The fluid injection device according to claim 1,
The fluid injection device according to claim 1, wherein the pump includes a plurality of fingers that sequentially push the tube. The fluid injection device according to claim 1 or 2,
The fluid injection device according to claim 1, wherein the tube is made of one of a styrene thermoplastic elastomer and an olefin thermoplastic elastomer. The fluid injection device according to any one of claims 1 to 3,
The controller drives the pump with a first drive amount when the temperature is the first temperature, and drives higher than the first drive amount when the temperature is lower than the first temperature. A fluid injection device for driving the pump by a quantity. The fluid injection device according to any one of claims 1 to 4,
The fluid injection device according to claim 1, wherein the temperature measurement unit includes an electric resistance member that is in close contact with the tube. A fluid injection device according to any one of claims 1 to 5,
The temperature measuring unit is
A first electrode whose electrical resistance changes with the temperature associated with the tube, the first electrode provided on a part of the circumference of the tube;
Sandwiching the tube together with the first electrode, and a second electrode at a position facing the first electrode,
Measure the temperature associated with the tube based on the change in electrical resistance of the first electrode, and mix bubbles in the tube based on the change in capacitance between the first electrode and the second electrode It is determined whether or not the fluid injection device. The fluid injection device according to claim 6,
The fluid injection device according to claim 1, wherein the first electrode is formed such that one resistance wire is bent and a plurality of the resistance wires are arranged in parallel. The fluid injection device according to claim 6 or 7,
The fluid injection device according to claim 1, wherein the second electrode is a plate-like member.