JP2014147595A - Living body monitoring system - Google Patents

Abstract

PROBLEM TO BE SOLVED: To adjust a balance between reduction in processing burden in information generating processing and improvement in real time display performance of biological information, in accordance with necessity of living body monitoring.SOLUTION: Pressure according to the body movement of a living body P1 at a monitoring place B acts on a tube-like pressure sensor part 11. A signal generation part 12 generates biological signals on the basis of the inner pressure change of the pressure sensor part 11. A signal processing part 13 repeatedly performs information generating processing generating the biological information on life activity of the living body P1 on the basis of the biological signals generated by the signal generation part 12, on the basis of a predetermined performance cycle, and is structured so as to change the performance cycle. A biological information notification part 14 displays the biological information generated by the signal processing part 13.

Description

  The present invention relates to a living body monitoring system for monitoring a living body.

  2. Description of the Related Art Conventionally, a living body monitoring system that monitors a living body by detecting and processing a signal derived from a living activity (respiration, heartbeat, etc.) from a living body such as a human or an animal using various sensors is known (for example, Patent Document 1). In such a living body monitoring system, a living body information related to a living body's living body activity is notified to a monitoring person (for example, a doctor) based on a signal detected from a living body (for example, a patient), so Let me confirm. For example, in the living body monitoring device of Patent Document 1, the waveform of the heart sound signal and the respiratory signal extracted from the output signal of the heartbeat / respiration sensor is displayed on the monitor.

JP 2006-129933 A

  By the way, in the living body monitoring apparatus of Patent Document 1, the living body information displayed on the monitor is updated at a constant cycle. However, when the necessity for monitoring the living body is high (for example, the state of the living activity changes suddenly). In the case where the biological information is updated, it is preferable to improve the real-time display property of the biological information by shortening the update period of the biological information. On the other hand, when the necessity for monitoring the living body is low (for example, when the state of the biological activity is stable), a process for generating the biological information by increasing the update period of the biological information (hereinafter, It is preferable to reduce the processing burden of “information generation processing”. However, since the living body monitoring apparatus of Patent Document 1 simply displays living body information, the processing load of the information generation processing is reduced and the real time display property of living body information is improved according to the necessity of monitoring the living body. It was difficult to adjust the balance.

  Accordingly, the present invention provides a living body monitoring system capable of adjusting the balance between the reduction of the processing burden of information generation processing and the improvement of real time displayability of living body information according to the necessity of monitoring of a living body. Objective.

  The first invention is a tubular pressure-sensitive part (11) that is installed at a predetermined monitoring place (B) and on which a pressure associated with body movement of the living body (P1) at the monitoring place (B) acts. A signal generation unit (12) that generates a biological signal based on a change in internal pressure of the pressure sensing unit (11), and a biological activity of the biological body (P1) based on the biological signal generated by the signal generation unit (12) Information generation processing for generating biometric information on the basis of a predetermined execution cycle, a signal processing unit (13) configured to be able to change the execution cycle, and the signal processing unit (13 And a biological information notifying unit (14) for displaying the biological information generated by (2).

  In the first invention, the execution cycle of the information generation process can be changed, so that the pause time of the information generation process by the signal processing unit (13) and the update period of the biological information in the biological information notification unit (14) are determined. Will be able to change. For example, by increasing the execution period of the information generation process, the biometric information update period becomes longer, but the pause time of the information generation process becomes longer, so the processing load of the information generation process can be reduced. On the other hand, by shortening the execution period of the information generation process, the pause time of the information generation process is shortened, but the update period of the biological information can be shortened, so that the real-time display property of the biological information can be improved. .

  In a second aspect based on the first aspect, the signal processing unit (13) determines whether or not there is a sudden change in the state of the biological activity of the living body (P1) based on the biological signal generated by the signal generating unit (12). In the sudden change determination process and the sudden change determination process, when it is determined that there is no sudden change in the state of life of the living body (P1), the execution cycle is set to the first period, and in the sudden change determination process When it is determined that there is a sudden change in the state of the biological activity of the living body (P1), a cycle control process is performed to set the execution cycle to a second cycle shorter than the first cycle. It is the living body monitoring system characterized by being.

  In the second aspect of the invention, the pause time of the information generation process and the update period of the biological information can be changed according to the determination result of the sudden change determination process. For example, when the state of the biological activity of the living body (P1) is stable (that is, when the necessity for monitoring the living body (P1) is low), the execution cycle of the information generation process is set to the first period (the second period) By setting the period longer than the period, the pause time of the information generation process becomes longer, so that the processing load of the information generation process can be reduced. On the other hand, when the state of the biological activity of the living body (P1) is suddenly changed (that is, when the necessity for monitoring the living body (P1) is high), the execution cycle of the information generation process is set to the second period (the first period) By setting the cycle shorter than the cycle, the biometric information update cycle is shortened, so that the real-time display property of the biometric information can be improved.

  According to a third aspect of the present invention, in the second aspect, the signal processing unit (13) is configured such that when the execution cycle of the information generation process is set to the first cycle, When the information generation process is performed to generate the first biological information, and the execution cycle of the information generation process is set to the second period, the biological information is subjected to the second information generation process and the second information generation process is performed. 2 is generated, the processing load of the first information generation processing is less than the processing load of the second information generation processing, and the information amount of the first biological information is The biological monitoring system is characterized by being smaller than the amount of information of the second biological information.

  In the said 3rd invention, the information content of biometric information can be changed according to the determination result of the sudden change determination process. For example, when the execution period of the information generation process is set to the first period, the information amount of the biological information can be reduced, so that the processing load of the information generation process can be reduced. On the other hand, when the execution cycle of the information generation process is set to the second cycle, the amount of biological information can be increased, so that detailed biological information can be displayed.

  In a fourth aspect based on the third aspect, when the signal processing unit (13) switches the execution period of the information generation process from the first period to the second period, the sudden change determination process is performed. The second biological information is generated based on the biological signal in the period before the sudden change before the time when it is determined that there is a sudden change in the state of the biological activity of the biological body (P1). This is a characteristic biological monitoring system.

  In the fourth aspect of the invention, detailed biological information about the state of the biological activity of the living body (P1) before the sudden change of state can be generated, so that the state determination of the living body (P1) by the supervisor (P2) is supported. Can do.

  According to a fifth invention, in any one of the second to fourth inventions, the biological signal includes a body motion signal including a rough motion component derived from the rough motion of the living body (P1), the living body (P1 ) And at least the body motion signal from the heartbeat signal derived from the heartbeat of the living body (P1), and the signal processing unit (13) A living body monitoring system configured to detect the presence or absence of coarse movement of (P1) and to execute the sudden change determination process according to the presence or absence of rough movement of the living body (P1).

  In the fifth aspect of the invention, changes in the monitoring status accompanying coarse movement of the living body (P1) (for example, the presence or absence of the living body (P1) in the monitoring location (B), the change in the state of the living body's biological activity, etc.) The sudden change determination process can be executed in consideration. Thereby, the presence or absence of a sudden change in the state of life activity of the living body (P1) can be accurately determined.

  According to a sixth invention, in the fifth invention, the signal processing unit (13) has no body movement of the living body (P1) after the rough movement of the living body (P1) based on the body movement signal. When detected, the biological monitoring system is configured to stop the sudden change determination process.

  In the sixth aspect of the invention, when there is no body movement of the living body (P1) after the rough movement of the living body (P1), it can be considered that the living body (P1) is separated from the monitoring location (B). Therefore, the sudden change determination process can be stopped in a period (absence period) in which the living body (P1) is not present in the monitoring place (B). Thereby, the erroneous determination in an absent period can be prevented.

  According to a seventh aspect, in the sixth aspect, the signal processing unit (13) has a body movement of the living body (P1) after the rough movement of the living body (P1) based on the body movement signal. When detected, the first criterion corresponding to the state of the biological activity when the biological body (P1) is at rest is used as a criterion for determining whether or not the biological activity state of the biological body (P1) is suddenly changed in the sudden change determination process. To a second reference corresponding to the state of life activity after coarse movement of the living body (P1).

  In the seventh aspect of the present invention, when there is a body movement of the living body (P1) after the rough movement of the living body (P1), it can be considered that the living body (P1) is moving at the monitoring location (B). Therefore, when the living body (P1) is moving at the monitoring place (B), the determination criterion in the sudden change determination processing is the second criterion (that is, the criterion corresponding to the state of the biological activity after the rough movement of the living body (P1)). ) Can be set. Thereby, the sudden change determination process can be executed in consideration of the state change of the biological activity accompanying the coarse movement of the living body (P1).

  In an eighth aspect based on the fifth aspect, when the signal processing unit (13) detects the coarse movement of the living body (P1) based on the body movement signal, the living body (P1 ) To determine whether or not there is a sudden change in the state of the biological activity from the first reference corresponding to the state of the biological activity when the biological body (P1) is at rest, the biological body after the coarse movement of the biological body (P1) A biological monitoring system configured to change to a second standard corresponding to an activity state.

  In the eighth invention, when there is rough movement of the living body (P1), the determination criterion in the sudden change determination processing corresponds to the second reference (that is, the state of the biological activity after the rough movement of the living body (P1)). Standard). Thereby, the sudden change determination process can be executed in consideration of the state change of the biological activity accompanying the coarse movement of the living body (P1).

  In a ninth aspect based on the seventh aspect or the eighth aspect, the signal processing unit (13) is configured so that the determination criterion in the sudden change determination processing returns from the second criterion to the first criterion. A biological monitoring system configured to correct the determination criterion based on an elapsed time from the detection of coarse motion in (P1).

  In the ninth aspect of the invention, the state of the biological activity of the living body (P1) is changed with the coarse movement of the living body (P1), and then returns to the resting state with the passage of time. Therefore, the determination criterion in the sudden change determination process can be corrected based on the progress until the biological activity of the living body (P1) returns from the fluctuation state to the resting state. Thereby, the sudden change determination process can be executed in consideration of the return from the fluctuation state of the biological activity of the living body (P1) to the resting state.

  In a tenth aspect based on the fifth aspect, when the signal processing unit (13) detects the coarse movement of the living body (P1) based on the body movement signal, the coarse movement of the living body (P1) is detected. The biological monitoring system is configured to stop the sudden change determination process during a period from detection until a predetermined return time elapses.

  In the tenth aspect of the invention, the state of the biological activity of the living body (P1) is changed with the coarse movement of the living body (P1), and then returns to the resting state with the passage of time. Therefore, the sudden change determination process can be stopped in a period (variation period) until the biological activity of the living body (P1) returns from the fluctuation state to the resting state. Thereby, the misjudgment in the fluctuation | variation period of the biological activity of a biological body (P1) can be prevented.

  In an eleventh aspect of the invention, in any one of the fifth to tenth aspects, a coarse motion determination threshold value for detecting the presence or absence of coarse motion of the living body (P1) in the signal processing unit (13) is as follows: The living body monitoring system, wherein the living body (P1) is set to a value corresponding to at least one of the respiratory signal and the heartbeat signal extracted during normal rest.

  In the eleventh aspect, since the coarse motion determination threshold is set according to at least one of respiration and heartbeat when the living body (P1) is in a normal rest, the individual difference of the living body (P1) and the pressure-sensitive part (11) Detection errors due to variations (for example, manufacturing errors and installation errors) can be reduced. Thereby, the presence or absence of coarse movement of the living body (P1) can be accurately detected.

  In a twelfth aspect based on any one of the second to eleventh aspects, the signal processing unit (13) performs a signal transmission process of transmitting the biological signal generated by the signal generation unit (12). The signal transmission unit (301) that executes the sudden change determination process and the period control process repeatedly, and a biological signal periodically transmitted from the signal transmission unit (301) are repeatedly executed based on the execution period. A biological monitoring system comprising: a signal reception unit (302) that performs a signal reception process and an information generation process for generating the biological information based on a biological signal received by the signal reception process It is.

  In the twelfth aspect, by changing the execution cycle of the signal transmission process in the signal transmission unit (301), the execution cycle of the information generation process in the signal reception unit (302) is changed. As a result, the biological information notification unit The biometric information update cycle in (14) is changed. Further, by generating biological information based on the biological signal transmitted from the signal transmission unit (301) to the signal receiving unit (302) and supplying the biological information to the biological information notification unit (14), it is separated from the biological body (P1). Biological information related to the living body (P1) can be provided to the supervisor (P2) at the place. Furthermore, by changing the execution cycle of the information generation process according to the determination result of the sudden change determination process, the pause time of the signal transmission process can be changed according to the state of the biological activity of the living body (P1). For example, when the state of the biological activity of the living body (P1) is stable (that is, when the necessity for monitoring the living body (P1) is low), the execution cycle of the signal transmission process is set to the first period (the second period). By setting the cycle longer than the cycle, the pause time of the signal transmission process can be extended.

  In a thirteenth aspect based on the twelfth aspect, the signal transmission unit (301) performs the first signal transmission process when the execution period of the signal transmission process is set to the first period. When the information generation process is set to the second period, the biological signal is transmitted by the second signal transmission process. The biological monitoring system is characterized in that the information amount of the biological signal transmitted by the first signal transmission process is smaller than the information amount of the biological signal transmitted by the second signal transmission process.

  In the thirteenth aspect, the information amount (communication amount) of the biological signal transmitted from the signal transmission unit (301) to the signal reception unit (302) can be changed according to the determination result of the sudden change determination process. For example, when the execution cycle of the information generation process is set to the first cycle, the communication amount can be reduced, so that the processing load of the information generation process can be reduced. On the other hand, when the execution cycle of the information generation process is set to the second cycle, the amount of communication can be increased, so that detailed biological information can be displayed.

  In a fourteenth aspect based on the thirteenth aspect, when the signal transmission unit (13) switches the execution period of the signal transmission process from the first period to the second period, the sudden change determination process is performed. The biological signal in the period before the sudden change before the time when it is determined that there is a sudden change in the state of the biological activity of the biological body (P1) is transmitted by the second signal transmission process. It is a living body monitoring system.

  In the fourteenth aspect of the invention, detailed biological information about the state of the biological activity of the living body (P1) before the sudden change of state can be generated, so that the state determination of the living body (P1) by the monitor (P2) is supported. Can do.

  A fifteenth aspect of the present invention further includes an operation unit (15) that is operated by a supervisor (P2) and is given period information regarding the execution period in the first aspect of the invention, and the signal processing unit (13) includes: A biological monitoring system configured to execute a cycle control process for changing the execution cycle based on cycle information given to an operation unit (15).

  In the fifteenth aspect, the execution cycle of the information generation process can be changed by the operation of the supervisor (P2).

  In a sixteenth aspect based on the fifteenth aspect, the period information transmitting unit (16) for transmitting the period information given to the operation unit (15) and the period information from the period information transmitting unit (16) A period information receiving unit (17) for receiving, and the signal processing unit (13) repeats signal transmission processing for transmitting a biological signal generated by the signal generation unit (12) based on the execution cycle. And a signal transmission unit (301) that executes a cycle control process for changing the execution cycle based on the cycle information received by the cycle reception unit (17), and a periodic transmission from the signal transmission unit (301). A signal receiving unit (302) for executing a signal receiving process for receiving a biomedical signal transmitted to the mobile station and an information generating process for generating the biometric information based on the biomedical signal received by the signal receiving process. It is characterized by being That is a biological monitoring system.

  In the sixteenth aspect, by changing the execution cycle of the signal transmission process in the signal transmission unit (301), the execution cycle of the information generation process in the signal reception unit (302) is changed. As a result, the biological information notification unit The biometric information update cycle in (14) is changed. Further, by generating biological information based on the biological signal transmitted from the signal transmission unit (301) to the signal receiving unit (302) and supplying the biological information to the biological information notification unit (14), it is separated from the biological body (P1). Biological information related to the living body (P1) can be provided to the supervisor (P2) at the place. Also, by supplying the cycle information given to the operation unit (15) by the supervisor (P2) to the signal transmission unit (301) via the cycle information transmission unit (16) and the cycle information reception unit (17). The execution cycle of the signal transmission process can be changed by the operation of the supervisor (P2) located away from the living body (P1). Furthermore, the pause time of the signal transmission process can be changed based on the period information given to the operation unit (15) by the supervisor (P2).

  According to the first invention, by making it possible to change the execution cycle of the information generation process, the processing load of the information generation process can be reduced according to the necessity of monitoring the living body (P1) and the real-time display property of the biological information can be reduced. The balance with improvement can be adjusted.

  According to the second invention, since the pause time of the information generation process and the update cycle of the biological information can be changed according to the determination result of the sudden change determination process, the information according to the state of the biological activity of the living body (P1) It is possible to automatically adjust the balance between the reduction of the processing load of the generation process and the improvement of the real-time display property of the biological information.

  According to the third invention, since the information amount of the biological information can be changed according to the determination result of the sudden change determination process, the information generation process is performed when the state of the biological activity of the living body (P1) is stable. The processing burden can be further reduced.

  According to the fourth aspect of the invention, it is possible to assist the monitoring person (P2) in determining the state of the living body (P1), so that the burden of living body monitoring by the monitoring person (P2) can be reduced.

  According to the fifth invention, since it is possible to accurately determine the presence or absence of a sudden change in the state of the biological activity of the living body (P1), the balance between reducing the processing load of the information generation process and improving the real-time display property of the biological information Can be automatically adjusted appropriately.

  According to the sixth aspect of the invention, it is possible to prevent erroneous determination in the absence period of the living body (P1), and therefore it is possible to accurately determine whether there is a sudden change in the state of life of the living body (P1).

  According to the seventh and eighth inventions, the sudden change determination process can be executed in consideration of the change in the state of the life activity associated with the coarse movement of the living body (P1). The presence or absence of can be accurately determined.

  According to the ninth invention, since the sudden change determination process can be executed in consideration of the return from the fluctuation state of the biological activity of the living body (P1) to the resting state, the sudden change in the state of the biological activity of the living body (P1) can be performed. Presence / absence can be accurately determined.

  According to the tenth invention, it is possible to prevent an erroneous determination in the fluctuation period of the biological activity of the living body (P1) (the fluctuation period after the coarse movement of the living body (P1)). Whether or not there is a sudden change in state can be accurately determined.

  According to the eleventh aspect, since the presence / absence of rough movement of the living body (P1) can be accurately detected, it is possible to accurately determine the presence / absence of a sudden change in the state of life of the living body (P1).

  According to the twelfth invention, since the biological information related to the living body (P1) can be provided to the monitoring person (P2) located away from the living body (P1), the monitoring person is located away from the living body (P1). The monitoring of the living body (P1) by (P2) can be supported. In addition, when the state of the biological activity of the living body (P1) is stable (that is, when the necessity for monitoring the living body (P1) is low), it is possible to extend the pause time of the signal transmission process. The amount of communication between the transmission unit (301) and the signal reception unit (302) can be reduced.

  According to the thirteenth aspect, the information amount (communication amount) of the biological signal transmitted from the signal transmission unit (301) to the signal reception unit (302) can be changed according to the determination result of the sudden change determination process. The amount of communication can be further reduced when the state of the biological activity of the living body (P1) is stable.

  According to the fourteenth aspect of the invention, it is possible to support the state determination of the living body (P1) by the monitoring person (P2), so that the burden of monitoring the living body by the monitoring person (P2) can be reduced.

  According to the fifteenth aspect, since the execution cycle of the information generation process can be changed by the operation of the monitor (P2), the processing load of the information generation process can be reduced and the living body can be changed according to the request of the monitor (P2). The balance with the improvement of the real-time display property of information can be adjusted.

  According to the sixteenth invention, since the biological information related to the living body (P1) can be provided to the monitoring person (P2) located away from the living body (P1), the monitoring person is located away from the living body (P1). The monitoring of the living body (P1) by (P2) can be supported. Further, since the pause time of the signal transmission process can be changed based on the period information given to the operation unit (15) by the supervisor (P2), the signal transmission unit (P2) can be changed according to the request of the supervisor (P2). 301) and the amount of communication between the signal receiving unit (302) can be reduced.

1 is a block diagram illustrating a configuration example of a biological monitoring system according to a first embodiment. Schematic for demonstrating a non-restraint sensor. The wave form diagram for demonstrating a respiration signal. The wave form diagram for demonstrating a heartbeat signal. The graph for demonstrating the time change of the respiration rate. 5 is a flowchart for explaining a sudden change determination process according to the first embodiment. The flowchart for demonstrating the repeated execution of an information generation process. The flowchart for demonstrating a period control process. The wave form diagram for demonstrating Chain Stokes respiration. The wave form diagram for demonstrating biorespiration. The wave form diagram for demonstrating respiratory gradual reduction. The wave form diagram for explaining apnea. A graph to explain circadian rhythm. The wave form diagram for demonstrating the relationship between a patient's body motion and the fluctuation | variation of a body motion signal. The wave form diagram for demonstrating the relationship between a patient's coarse motion and the state of life activity. The wave form diagram for demonstrating the relationship between the coarse motion at the time of a patient's turning and getting out of bed, and the fluctuation | variation of a body motion signal. The wave form diagram for demonstrating the relationship between the fluctuation | variation of a body motion signal and the coarse motion at the time of a patient's getting off and entering a bed. The flowchart for demonstrating normal determination mode. The flowchart for demonstrating the irregular determination mode. The flowchart for demonstrating determination standby mode. 9 is a flowchart for explaining a sudden change determination process according to the second embodiment. The flowchart for demonstrating determination interruption mode. FIG. 9 is a block diagram illustrating a configuration example of a living body monitoring system according to a third embodiment. The flowchart for demonstrating the repeated execution of a signal transmission process. FIG. 9 is a block diagram illustrating a configuration example of a biological monitoring system according to a fourth embodiment. FIG. 10 is a block diagram illustrating a configuration example of a biological monitoring system according to a fifth embodiment.

  Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. In the drawings, the same or corresponding parts are denoted by the same reference numerals, and description thereof will not be repeated.

(Embodiment 1)
FIG. 1 shows a configuration example of a living body monitoring system (1) according to the first embodiment. This living body monitoring system (1) informs a doctor (P2) (healthcare worker) of biological information related to a patient's (P1) life activity (for example, breathing and heartbeat), so that the patient (P1) ) Monitoring.

  The biological monitoring system (1) includes a pressure-sensitive unit (11) (pressure-sensitive unit), a signal generation unit (12), a signal processing unit (13), and a biological information notification unit (14). ing. In this example, the signal generation unit (12) includes a pressure receiving unit (201) and an extraction unit (202). The signal generation unit (12) and the signal processing unit (13) are provided in the main unit (21) of the unconstrained sensor (20).

<Pressure-sensitive unit (pressure-sensitive part)>
As shown in FIG. 2, the pressure-sensitive unit (11) includes a pressure-sensitive tube (101), a blocking portion (102) that closes one end of the pressure-sensitive tube (101), and the other end of the pressure-sensitive tube (101). And a communication tube (103) to be connected. The pressure-sensitive unit (11) (especially the pressure-sensitive tube (101)) is placed between the bed bed of the bedding (B) and the mattress that will be monitored by the patient (P1), and the patient in the bedding (B) The pressure associated with body movement (P1) is applied.

  The pressure-sensitive tube (101) and the communication tube (103) are made of a material having flexibility and elasticity. The inner diameter of the pressure-sensitive tube (101) is approximately the same as the outer diameter of the communication tube (103). One end of the communication tube (103) is fitted into the other end of the pressure sensitive tube (101). The other end of the communication tube (103) is connected to the pressure receiving part (201) of the main unit (21). Thereby, the pressure-sensitive unit (11) is sealed by the blocking part (102) and the pressure receiving part (201).

<Pressure receiving part>
The pressure receiving part (201) converts the internal pressure change of the pressure sensitive unit (11) into a pressure signal (electrical signal). For example, the pressure receiving part (201) is configured by a microphone provided in the main unit (21). When the internal pressure of the pressure sensitive unit (11) changes with the body movement of the patient (P1) in the bedding (B), a pressure signal corresponding to the internal pressure change of the pressure sensitive unit (11) is output from the pressure receiving unit (201). The

<Extraction part>
The extraction unit (202) extracts a body motion signal from the pressure signal obtained by the pressure receiving unit (201). More specifically, the extraction unit (202) integrates and averages the pressure signal obtained by the pressure receiving unit (201) to 100 [sample / sec]. Next, the extraction unit (202) extracts a signal in a band (4 to 10 Hz) corresponding to the natural vibration band of the human body from this signal. Next, the extraction unit (202) performs rectification (absolute value) on the signal and then performs peak hold processing (so-called envelope detection processing) at a predetermined time. Next, the extraction unit (202) extracts a signal of a relatively low frequency vibration band (0.5 Hz) from this signal, and performs integration and averaging on this signal at intervals of about 10 seconds (or the signal Calculate the standard deviation at similar intervals). By executing such processing, it is possible to generate a body motion signal in which the body motion of the patient (P1) is noticeable. The patient's (P1) body movement is caused by fine movement derived from the patient's (P1) breathing and heartbeat, and rough movements that occur when the patient (P1) enters, leaves, or turns over. It is broadly classified as dynamic. That is, in this example, the body motion signal includes a coarse motion component derived from the coarse motion of the patient (P1) and a fine motion component derived from the breathing and heartbeat of the patient (P1).

  Further, in this example, the extraction unit (202) uses the breathing-derived frequency component (for example, a frequency corresponding to 12 to 30 times / minute which is the number of normal breaths) from the pressure signal obtained by the pressure receiving unit (201). By extracting the component, a respiration signal (see FIG. 3) derived from the respiration of the patient (P1) is generated. Further, the extraction unit (202) extracts a frequency component derived from a heartbeat (for example, a frequency component corresponding to 45 to 120 beats / minute, which is the number of normal heartbeats) from the body motion signal, so that the patient (P1) A heartbeat signal (refer to FIG. 4) derived from the heartbeats of the present is generated. The extraction unit (202) also stores the time (the time when the signal level value was acquired) in association with the signal level values of the body motion signal, the respiratory signal, and the heartbeat signal. For example, the extraction unit (202) is configured by a filter circuit, a memory, and the like provided in the main unit (21). In the following description, a general term for a body motion signal, a respiratory signal, and a heartbeat signal is referred to as “biological signal”.

<Signal processing section>
The signal processing unit (13) generates biological information related to the biological activity of the patient (P1) based on the biological signals (body motion signal, respiratory signal, and heartbeat signal) generated by the signal generation unit (12) ( The information generation process) is repeatedly executed based on a predetermined execution cycle. Specifically, the signal processing unit (13) repeatedly executes a process of generating display data for displaying the biological information on the biological information notifying unit (14) based on the body motion signal, the respiratory signal, and the heartbeat signal. To do. The biological information includes, for example, a body motion signal waveform, a respiratory signal waveform, a heartbeat signal waveform, a temporal change in respiratory rate (see FIG. 5), a temporal change in heart rate, and a maximum / minimum respiratory rate. , Heart rate maximum / minimum values are included. The repeated execution of the information generation process will be described in detail later.

  The signal processing unit (13) is configured to be able to change the execution cycle of the information generation process. For example, the signal processing unit (13) is configured by a CPU, a memory, and the like provided in the main unit (21).

  Furthermore, in this example, the signal processing unit (13) is configured so that the biological signal generated by the signal generation unit (12) (specifically, the body motion signal, the respiratory signal, And at least one of the heartbeat signals), a process for determining the presence or absence of a sudden change in the state of life of the patient (P1) (abrupt change determination process) is executed. Further, the signal processing unit (13) executes a cycle control process for controlling the execution cycle of the information generation process according to the determination result of the sudden change determination process.

<Biometric information notification unit>
The biometric information notification unit (14) executes a process (information display process) for displaying the biometric information generated by the information generation process of the signal processing unit (13). Specifically, the biological information notification unit (14) displays the biological information by performing display processing (processing for displaying biological information) on the display data output from the signal processing unit (13). (Not shown). For example, the biological information notifying unit (14) includes a waveform diagram of a body motion signal, a respiratory signal, and a heart rate signal, a graph showing temporal changes in the respiratory rate and the heart rate, the maximum / minimum value of the respiratory rate, Display the maximum / minimum values on the display. For example, the biological information notification unit (14) is configured by an audio / video reproduction device having a display and a speaker.

<Abrupt change judgment processing>
Next, a sudden change determination process by the signal processing unit (13) will be described with reference to FIG. The signal processing unit (13) captures and accumulates the signal level value of the biological signal (at least one of the body motion signal, the respiratory signal, and the heartbeat signal) from the signal generation unit (12), and stores the signal level of the biological signal. When the accumulated number of values reaches a predetermined number (the number required for executing the sudden change determination process), the sudden change determination process is executed. In the following description, it is assumed that the initial value of the count value (n) indicating the accumulated number of signal level values of the biological signal is set to zero. The predetermined value (MAX) corresponds to the number of signal level values necessary for executing the sudden change determination process.

<Step (ST11, ST12, ST13, ST14)>
First, the signal processing unit (13) takes the signal level value of the biological signal from the signal generation unit (12) (step (ST11)), and adds “1” to the count value (n) (step (ST12)). . Then, the signal processing unit (13) determines whether or not the count value (n) has reached a predetermined value (MAX) (step (ST13)). If it is determined that the count value (n) has not reached the predetermined value (MAX), the process proceeds to step (ST11). On the other hand, when it is determined that the count value (n) has reached the predetermined value (MAX), the signal processing unit (13) uses the signal level value of the accumulated biological signal and a predetermined determination criterion. Based on this, sudden change determination processing is started (step (ST14)).

<< Step (ST15, ST16, ST17, ST18, ST19) >>
Next, the signal processing unit (13) determines whether or not the determination criterion in the sudden change determination process is satisfied based on the signal level value of the accumulated biological signal (step (ST15)). When the signal processing unit (13) determines that the determination criterion in the sudden change determination process is satisfied, the signal processing unit (13) outputs a determination result indicating that the state of the biological activity of the patient (P1) is suddenly changed (step S1). (ST16)), if it is determined that the criteria in the sudden change determination process are not satisfied, the determination result indicating that the state of life activity of the patient (P1) has not changed suddenly (or is stable) Is output (step (ST17)). Next, the signal processing unit (13) sets the count value (n) to an initial value (zero) (step (ST18)). When the monitoring of the patient (P1) is continued (“NO” in step (ST18)), the process proceeds to step (ST11).

<Repeated information generation process>
Next, the repeated execution of the information generation process will be described with reference to FIG. First, the signal processing unit (13) takes in a biological signal (body motion signal, respiration signal, and heart rate signal) to be subjected to information generation processing from the signal generation unit (12) (step (ST21)). Next, the signal processing unit (13) generates biological information related to the biological activity of the patient (P1) based on the biological signal (step (ST22)). At this time, the signal processing unit (13) starts measuring the elapsed time since the generation of the biological information. When the monitoring of the patient (P1) is continued (“NO” in step (ST23)), the signal processing unit (13) determines whether the elapsed time from the generation of the biological information has reached the execution cycle. (Step (ST24)). When the elapsed time from the generation of the biological information reaches the execution cycle (that is, when the execution cycle has elapsed since the generation of the biological information), the signal processing unit (13) The body motion signal, the respiration signal, and the heartbeat signal) are captured from the signal generation unit (12) (step (ST21)).

<Cycle control processing>
Next, the cycle control process will be described with reference to FIG. First, the signal processing unit (13) confirms whether or not it is determined in the sudden change determination process that the state of life activity of the patient (P1) has changed suddenly (step (ST25)). Next, when it is determined in the sudden change determination process that the state of the biological activity of the patient (P1) has suddenly changed, the signal processing unit (13) sets the execution cycle of the information generation process to the second cycle (first (Step (ST26)), and it is determined in the sudden change determination process that the state of life activity of the patient (P1) has not changed suddenly. In this case, the execution cycle of the information generation process is set to the first cycle (hereinafter referred to as “long cycle”) (step (ST27)). Next, when monitoring the patient (P1) is continued (“NO” in step (ST28)), the process proceeds to step (ST25). In this way, the execution cycle of the information generation process is changed, and the biometric information update cycle is changed.

<Effects of Embodiment 1>
As described above, by changing the execution cycle of the information generation process, the pause time of the information generation process by the signal processing unit (13) and the update period of the biological information in the biological information notification unit (14) are changed. Will be able to. For example, by increasing the execution period of the information generation process, the biometric information update period becomes longer, but the pause time of the information generation process becomes longer, so the processing load of the information generation process can be reduced. On the other hand, by shortening the execution period of the information generation process, the pause time of the information generation process is shortened, but the update period of the biological information can be shortened, so that the real-time display property of the biological information can be improved. . Thus, the balance between the reduction of the processing burden of the information generation processing and the improvement of the real-time display property of the biological information can be adjusted according to the necessity of monitoring the patient (P1).

  In addition, the pause time of the information generation process and the update period of the biological information can be changed according to the determination result of the sudden change determination process. For example, when the state of the biological activity of the patient (P1) is stable (that is, when the necessity for monitoring the patient (P1) is low), the execution cycle of the information generation process is a long cycle (first cycle) By setting to, the pause time of the information generation process becomes longer, so that the processing load of the information generation process can be reduced. On the other hand, when the state of the biological activity of the patient (P1) is suddenly changed (that is, when the necessity for monitoring the patient (P1) is high), the execution cycle of the information generation process is short (second cycle). By setting to, the biometric information update cycle is shortened, so that the real-time display property of the biometric information can be improved. As described above, since the pause time of the information generation process and the update period of the biological information can be changed according to the determination result of the sudden change determination process, the process of the information generation process according to the state of the biological activity of the patient (P1) It is possible to automatically adjust the balance between reducing the burden and improving the real-time displayability of the biological information.

<Modification of information generation processing by signal processing unit>
The signal processing unit (13) performs the first information generation process on the biological signal and performs the first biological information when the execution period of the information generation process is set to a long period (first period). And when the execution cycle of the information generation processing is set to a short cycle (second cycle), the second biological information is generated by performing the second information generation processing on the biological signal. May be. Note that the processing burden of the first information generation process is less than the processing burden of the second information generation process. Further, the information amount of the first biological information is smaller than the information amount of the second biological information. For example, in the first information generation process, thinning out (or averaging) of biological signals, deletion of items displayed as biological information, and the like are executed.

  By configuring as described above, the amount of biological information can be changed according to the determination result of the sudden change determination process. For example, when the execution cycle of the information generation process is set to a long cycle, the amount of biological information can be reduced, so that the processing load of the information generation process can be reduced. On the other hand, when the execution cycle of the information generation process is set to a short cycle, the amount of biological information can be increased, so that detailed biological information can be displayed. Thereby, when the state of the biological activity of the patient (P1) is stable, the processing load of the information generation process can be further reduced.

  Furthermore, the signal processing unit (13), when switching the execution cycle of the information generation processing from the long cycle (first cycle) to the short cycle (second cycle), causes the patient's (P1) biological activity in the sudden change determination processing. The second biological information may be generated based on the biological signal in the period before the sudden change prior to the time when it is determined that there is a sudden state change (the time associated with the biological signal).

  By configuring as described above, detailed biological information about the state of life activity of the patient (P1) before the sudden change of state can be generated, so that the doctor (P2) supports the judgment of the state of the patient (P1). be able to. Thereby, the burden of monitoring by the doctor (P2) can be reduced.

<Modification of biometric information notification unit>
The biometric information notification unit (14) notifies the determination result (the presence or absence of a sudden change in the state of the biometric information of the patient (P1)) in parallel with the information display processing by the signal processing unit (13). Notification processing may be executed. Specifically, when it is determined that there is a sudden change in the state of the biological information of the patient (P1) in the sudden change determination process of the signal processing unit (13), the biological information notification unit (14) Notification voice (or notification video) indicating that the state of the patient has suddenly changed, and if it is determined that there is no sudden change in the state of the biological information of the patient (P1) in the sudden change determination process of the signal processing unit (13), the notification Stops outputting audio (or notification video). With this configuration, the doctor (P2) can assist the patient (P1) in determining the state of the patient (P1), and thus the burden of monitoring the patient (P1) by the doctor (P2) can be reduced.

<Specific example of sudden change determination processing>
Next, the sudden change determination process will be described with a specific example. The specific cases shown below often develop when the patient (P1) 's pathological condition worsens (particularly when the patient (P1) has a short life prognosis). The signal processing unit (13) may target all of the following specific cases for the sudden change determination process, or may include a part of the following specific cases for the sudden change determination process. It may be what you do.

<< Specific Example of Sudden Change Judgment Processing 1: Chain Stokes Breathing >>
FIG. 9 shows a waveform of a respiratory signal when the patient (P1) develops “Chain Stokes breathing”. “Chain Stokes breathing” is a breathing state in which the breathing amplitude repeatedly increases and decreases slowly. When “Chain Stokes Respiration” is the target of a sudden change determination process, the signal processing unit (13), when the waveform of the respiration signal can be regarded as a waveform when developing a Chain Stokes respiration, the living body of the patient (P1) It may be determined that the state of activity has suddenly changed. For example, in the signal processing unit (13), the length of the envelope of the respiratory signal falls within a predetermined cycle length range (a range of cycle lengths that can be regarded as Chain Stokes breathing), and , The fluctuation amount of the envelope of the respiratory signal (difference between the maximum value and the minimum value of the envelope) is larger than the predetermined fluctuation amount (the lower limit value of the fluctuation amount that can be regarded as Chain Stokes breathing) In this case, it may be determined that the state of the biological activity of the patient (P1) has suddenly changed.

<< Specific example of sudden change determination process 2: Bio-breathing >>
FIG. 10 shows the waveform of the respiratory signal when the patient (P1) has developed “bio-breathing”. “Bio-breathing” refers to a state of breathing that exhibits irregular breathing amplitude and cycle fluctuations. When “bio-breathing” is subject to sudden change determination processing, the signal processing unit (13) determines that the waveform of the breathing signal can be regarded as a waveform when the bio-breathing occurs, and the patient (P1) It may be determined that the state of activity has suddenly changed. For example, the signal processing unit (13) calculates the cycle length and amplitude for each respiratory cycle based on the fluctuation of the respiratory signal, and the variance value (variation) of the cycle length of the respiratory cycle and the variance value of the amplitude in the respiratory cycle ( (Variation), and when the dispersion value of the cycle length and the dispersion value of the amplitude are larger than the predetermined dispersion value (the lower limit value of the dispersion value that can be regarded as bio-respiration), the patient ( It may be determined that the state of life activity of P1) has suddenly changed.

<< Specific Example of Sudden Change Judgment Processing 3: Respiration Decrease / Heartbeat Decrease >>
FIG. 11 shows the waveform of the respiratory signal when the patient (P1) has developed “respiratory gradual decrease”. “Respiration gradual decrease” is a state in which respiration gradually weakens. In the case where “respiratory gradual decrease” is the target of sudden change determination processing, the signal processing unit (13) determines that the waveform of the respiratory signal can be regarded as a waveform when respiratory gradual decrease has occurred. It may be determined that the state has suddenly changed. For example, the signal processing unit (13) performs a linear regression process on a respiratory signal within a predetermined period (specifically, a signal level value at each time within the period) to change the time of the respiratory signal. The slope of the time change straight line of the respiratory signal is negative, and the slope amount of the time change straight line of the respiratory signal can be regarded as a predetermined slope amount (breathing gradually decreasing). When it is larger than the minimum value of the inclination amount, it may be determined that the state of the biological activity of the patient (P1) has suddenly changed.

  It should be noted that “gradual decrease in heart rate” may be the target of the sudden change determination process, similarly to “gradual decrease in breath”. “Heart rate gradual decrease” is a state in which the heart rate gradually weakens. In this case, the signal processing unit (13) may determine that the state of the biological activity of the patient (P1) has suddenly changed when the waveform of the heartbeat signal can be regarded as a waveform when the heartbeat gradually decreases.

<< Specific Example of Sudden Change Determination Process 4: Respiration Rate Graduation / Heart Rate Decrease >>
Further, “gradual decrease in respiratory rate” may be the target of the sudden change determination process. The “respiratory rate gradually decreases” is a state where the respiratory rate gradually decreases. In this case, the signal processing unit (13) calculates a temporal change in the respiratory rate based on the respiratory signal, and when the temporal change in the respiratory rate can be regarded as a temporal change when the respiratory rate gradually decreases, It may be determined that the state of life activity of P1) has suddenly changed. For example, the signal processing unit (13) calculates the respiration rate based on the respiration signal, performs a linear regression process on the respiration rate at each time within a predetermined period, and shows a time change of the respiration rate (Time change straight line) is calculated, the slope of the respiratory rate time change straight line is negative, and the slope of the respiratory rate time change straight line is a predetermined slope amount (a slope that can be regarded as a gradual decrease in respiratory rate) It may be determined that the state of the biological activity of the patient (P1) has suddenly changed when it is larger than the minimum amount.

  Note that, as with “gradual decrease in respiratory rate”, “gradual decrease in heart rate” may be the target of sudden change determination processing. “Heart rate gradually decreases” is a state in which the heart rate gradually decreases. In this case, the signal processing unit (13) calculates the time change of the heart rate based on the heart rate signal, and when the time change of the heart rate can be regarded as the time change when the respiratory rate gradually decreases, It may be determined that the state of life activity of P1) has suddenly changed.

<< Specific example 5 of sudden change determination processing: apnea / cardiac arrest >>
FIG. 12 shows the waveform of the respiratory signal when the patient (P1) has developed “apnea”. “Apnea” is a state where breathing is stopped (or a state where breathing is weak). When “apnea” is the target of the sudden change determination process, the signal processing unit (13) determines that the waveform of the respiratory signal can be regarded as the waveform when the patient is developing apnea. It may be determined that the state has suddenly changed. For example, when the signal level of the envelope of the respiratory signal is smaller than a predetermined signal level (maximum value of the signal level that can be regarded as apnea), the signal processing unit (13) It may be determined that the state of life activity of P1) has suddenly changed.

  Note that “cardiac arrest” may be the target of the sudden change determination process, as in “apnea”. “Cardiac arrest” refers to a state where the heartbeat is stopped (or a state where the heartbeat is weak). In this case, the signal processing unit (13) may determine that the state of the biological activity of the patient (P1) has suddenly changed when the waveform of the heartbeat signal can be regarded as a waveform when cardiac arrest occurs.

<< Specific example 6 of sudden change determination processing: Abnormal respiratory rate / abnormal heart rate >>
Note that “abnormal respiratory rate” may be the target of the sudden change determination process. “Abnormal respiratory rate” refers to a state of breathing that deviates from a normal respiratory rate range (for example, a range of 9 times / minute to 24 times / minute). In this case, the signal processing unit (13) calculates the respiration rate based on the respiration signal, and the respiration rate deviates from a predetermined respiration rate range (a range that can be regarded as a normal respiration rate). In this case, it may be determined that the state of the biological activity of the patient (P1) has suddenly changed.

  Similarly to “abnormal respiratory rate”, “abnormal heart rate” may be the target of sudden change determination processing. A heart rate abnormality is a state of a heart rate that deviates from a normal heart rate range (for example, a range of 45 beats / minute to 120 beats / minute). In this case, the signal processing unit (13) calculates a heart rate based on the heart rate signal, and the heart rate deviates from a predetermined heart rate range (a range that can be regarded as a normal heart rate). In this case, it may be determined that the state of the biological activity of the patient (P1) has suddenly changed.

<< Example 7 of sudden change determination process: disappearance of circadian rhythm >>
FIG. 13 shows the time change of the respiratory rate (white circle) when there is a circadian rhythm and the time change of the respiratory rate (black circle) when there is no circadian rhythm. The circadian rhythm is the fluctuation pattern of the life activity (especially respiratory rate and heart rate) of the patient (P1) that fluctuates in a cycle of about 24 hours. If the patient's (P1) pathology deteriorates or the patient (P1 ) Often disappears when it becomes cloudy (or comatose). When “disappearance of circadian rhythm” is a target of the sudden change determination process, the signal processing unit (13) calculates a respiration rate (or heart rate) based on the respiration signal (or heart rate signal), and the respiration rate ( Alternatively, when the time change in heart rate does not indicate circadian rhythm, it may be determined that the state of life activity of the patient (P1) has suddenly changed. For example, the signal processing unit (13) performs a fast Fourier transform on the daily respiratory rate (or heart rate) to calculate a fluctuation pattern indicating a temporal change in the respiratory rate (or heart rate), The cycle length of the fluctuation pattern of the respiratory rate (or heart rate) deviates from a predetermined cycle length range (a range of cycle length that can be regarded as having circadian rhythm), and the respiratory rate (or heart rate) Number) fluctuation pattern amplitude is smaller than a predetermined amplitude (the lower limit value of the amplitude that can be considered to have circadian rhythm), the patient's (P1) life activity state suddenly changed You may judge.

<< Example 8 of sudden change determination process: Abnormal body movement >>
It should be noted that “abnormal body motion” may be the target of the sudden change determination process. “Body Abnormality” means that the patient (P1) has frequent fluttering such as convulsions (excessive body movement), and the patient (P1) does not have fluttering such as coma (or (Very few) state (disappearance of body movement). In this case, the signal processing unit (13) detects the coarse movement of the patient (P1) based on the body movement signal, and the number of coarse movements within a predetermined period is within a predetermined number of times (normal It may be determined that the state of the biological activity of the patient (P1) has suddenly changed when it deviates from the range of the number of times that can be regarded as body movement. That is, in this case, the signal processing unit (13) detects the presence or absence of coarse movement of the patient (P1) based on the body movement signal, and executes the sudden change determination process according to the presence or absence of the coarse movement of the patient (P1). Will be.

<Coarse motion judgment threshold setting>
The coarse motion determination threshold value may be a fixed value or a variable value. In addition, the coarse motion determination threshold value may be set to a value corresponding to at least one of a respiratory signal and a heartbeat signal (a respiratory signal and a heartbeat signal extracted during normal rest) when the patient (P1) is at normal rest. . For example, the coarse motion determination threshold value may be set such that the coarse motion determination threshold value increases as the amplitude of the respiratory signal (or the amplitude of the heartbeat signal) increases during normal rest.

  As described above, by setting the coarse motion determination threshold according to at least one of breathing and heartbeat during normal rest of the patient (P1), individual differences in the patient (P1) and variations in the pressure-sensitive unit (11) Detection errors due to (for example, manufacturing errors and installation errors) can be reduced. Thereby, since the presence or absence of the coarse movement of the patient (P1) can be accurately detected, it is possible to accurately determine the presence or absence of a sudden change in the state of the biological activity of the patient (P1).

  The coarse motion determination threshold value may be updated based on the minimum amplitude of the body motion signal within a predetermined period (a period longer than the respiratory cycle, for example, 10 seconds or longer). For example, the signal processing unit (13) may update the coarse motion determination threshold by performing the following processing. That is, the signal processing unit (13) detects the minimum amplitude of the body motion signal within a predetermined period, and calculates the update threshold by multiplying the minimum amplitude of the body motion signal by a predetermined constant. . Next, when the update threshold is smaller than the current coarse motion determination threshold, the signal processing unit (13) sets the update threshold as a new coarse motion determination threshold. On the other hand, when the update threshold is larger than the current coarse motion determination threshold, the signal processing unit (13) updates the update threshold and the current coarse motion determination threshold so that the ratio of the current coarse motion determination threshold is larger than the update threshold. A value obtained by performing the weighted average processing is set as a new coarse motion determination threshold value.

(Embodiment 2)
The biological monitoring system (1) according to the second embodiment has the same configuration as that shown in FIG. 1, but the determination operation by the signal processing unit (13) is different. The signal processing unit (13) in the second embodiment switches the mode of the determination operation according to the presence / absence of coarse movement of the patient (P1) and the presence / absence of body movement of the patient (P1) after the coarse movement of the patient (P1). It is configured.

<Relationship between patient motion and body motion signal fluctuation>
Here, before describing the determination operation by the signal processing unit (13), referring to FIGS. 14 (a) to 14 (c), the body motion (coarse motion and fine motion) and body motion of the patient (P1) are described. The relationship with signal fluctuation will be described. FIG. 14A shows a waveform of the body motion signal when the patient (P1) is sleeping in the bedding (B). FIG. 14B is an enlarged waveform diagram obtained by enlarging the waveform of the portion surrounded by a circle in the body motion signal waveform shown in FIG. 14A, and FIG. It is the enlarged waveform figure which expanded the waveform of the part enclosed with the circle among the waveforms of the body motion signal shown by a). In FIG. 14 (a), the patient (P1) undergoes rough motion (in this example, turning over) at the time when the amplitude of the body motion signal is large.

《Coarse motion》
Of the body motion signal, the fluctuation of the coarse movement component derived from the coarse movement of the patient (P1) is much larger than the fluctuation of the fine movement component derived from the fine movement (respiration and heartbeat) of the patient (P1). For example, as shown in FIG. 14C, when the patient (P1) rolls over and the posture of the patient (P1) shifts from supine to lying down, the body motion signal greatly varies with the patient (P1) turning over. To do. The patient (P1) not only turns over, but also when the patient (P1) moves into the bedding (B) (bed-in operation) or when the patient (P1) moves away from the bedding (B) (bed-out operation). The body movement signal greatly fluctuates with the entering operation (or leaving operation). Therefore, it is possible to detect the presence or absence of coarse movement of the patient (P1) by comparing the amplitude (signal level value) of the body movement signal with a predetermined threshold (coarse movement determination threshold). For example, the coarse motion determination threshold is set to a value larger than the maximum amplitude of the fine motion component of the body motion signal (the maximum amplitude of the body motion signal when there is no coarse motion).

《Fine tremor》
Further, in FIG. 14C, during the period before and after the coarse movement (turning over) of the patient (P1), the body movement signal fluctuates with the body movement (fine movement) derived from the breathing and heartbeat of the patient (P1). Yes. Since the body motion (pulsation) derived from the heartbeat of the patient (P1) is generally smaller than the body motion (breathing motion) derived from the breathing of the patient (P1), FIG. 14 (a) to FIG. 14 (c). ), The fluctuation of the body motion signal accompanying the pulsation is buried in the fluctuation of the body motion signal accompanying the respiratory motion. The patient's (P1) body movement (tremor) derived from respiration and heartbeat mainly appears as movement (vibration) of the patient's (P1) chest and is prominent in the longitudinal direction of the patient's (P1) body. 14 (c), the amplitude of the fine motion component derived from the fine motion of the patient (P1) in the body motion signal is when the posture of the patient (P1) is “supine” or “prone” It is smaller when the posture of the patient (P1) is “recumbent”.

<Relationship between patient's flutter and state of life activity>
Next, the relationship between the coarse movement of the patient (P1) and the state of life activity (respiration and heartbeat) will be described with reference to FIG. FIG. 15 shows the waveform of the body motion signal when the patient (P1) is sleeping in the bedding (B) and the time change of the heart rate of the patient (P1).

  As shown in FIG. 15, when the patient's (P1) fluttering (in this example, turning over) occurs, the patient's (P1) heart rate increases from the normal value with the patient's (P1) fluttering, It returns to the normal value as time passes. For example, after the heart rate has increased from 60 beats / minute to 70 beats / minute due to the coarse movement of the patient (P1), the heart rate value returns to the normal value within a few minutes after the coarse movement of the patient (P1). The heartbeat amplitude of the patient (P1) also increases from the normal value with the coarse movement of the patient (P1), and then returns to the normal value with time. Furthermore, the respiration rate and respiration amplitude of the patient (P1) are similar to those of the heart rate and heartbeat amplitude associated with the coarse movement of the patient (P1). That is, the state of life activity (specifically, heart rate, heart rate amplitude, respiration rate, respiration amplitude) of the patient (P1) changed from the normal state to the fluctuating state with the patient (P1) coarse movement. After that, it returns from the fluctuation state to the normal state as time passes. In addition, the period (variation period) required for the patient's (P1) life activity to return from the fluctuation state to the stable state is the magnitude of the coarse movement of the patient (P1) (or the occurrence of the coarse movement of the patient (P1)). The number of times). For example, the fluctuation period tends to become longer as the coarse movement of the patient (P1) becomes larger (or as the number of occurrences of the coarse movement of the patient (P1) increases).

<Relationship between patient presence in bedding and fluctuations in body motion signals>
Next, with reference to FIG. 16, FIG. 17, the relationship between the presence or absence of the patient (P1) in bedding (B) and the fluctuation | variation of a body motion signal is demonstrated. FIG. 16 shows a waveform of a body motion signal when the patient (P1) turns over in the bedding (B) and then leaves the bedding (B), and FIG. 17 shows the waveform of the patient (P1) from the bedding (B). The waveform of the body motion signal when returning to the bedding (B) after leaving is shown.

  As shown in FIG. 16, when the patient (P1) turns over in the bedding (B), the body movement signal largely fluctuates with the turnover (coarse movement) of the patient (P1), and then the patient (P1) breaths. And fluctuates with heartbeat (tremor). On the other hand, when the patient (P1) moves away from the bedding (B), the body motion signal fluctuates greatly as the patient (P1) leaves the bed (coarse movement), but the patient (P1) moves away from the bedding (B). When it disappears, the patient (P1) does not move in the bedding (B), so the fluctuation of the body motion signal becomes weak (or zero). Specifically, when the patient (P1) disappears from the bedding (B), the amplitude of the body motion signal is the amplitude of the fine motion component (more specifically, derived from the patient's (P1) breathing and heartbeat (fine motion). The amplitude of the fine motion component when the posture of the patient (P1) is “recumbent” is smaller.

  In addition, as shown in FIG. 17, when the patient (P1) returns to the bedding (B) and enters the bedding (B), the body motion signal increases as the patient (P1) enters the floor (coarse movement). After fluctuating, it fluctuates with patient's (P1) breathing and heartbeat (tremor).

  Thus, when the patient (P1) is in the bedding (B), there is a body movement (fine movement) of the patient (P1) after the patient (P1) coarse movement. However, if the patient (P1) is not in the bedding (B), the patient (P1) does not move after coarse movement of the patient (P1), so the fluctuation of the body motion signal is weak. (Or zero). Therefore, the amplitude of the body motion signal after the patient (P1) coarse motion (specifically, the amplitude of the body motion signal (signal level value) immediately after the patient (P1) coarse motion is completed) is predetermined. The presence or absence of the patient (P1) in the bedding (B) can be detected by comparing the threshold (absence determination threshold). For example, the absence determination threshold value is set to a value smaller than the minimum amplitude of the fine motion component of the body motion signal when the posture of the patient (P1) is “recumbent” (the minimum amplitude of the body motion signal when there is no coarse motion). Has been.

<Determination operation by the signal processor>
Next, the determination operation by the signal processing unit (13) will be described with reference to FIG. 18, FIG. 19, and FIG. In this example, the signal processing unit (13) has a normal determination mode (FIG. 18), an irregular determination mode (FIG. 19), and a determination standby mode (FIG. 20). The judgment mode is switched according to the presence / absence and presence / absence of body movement of the patient (P1) after the patient (P1) coarse movement.

<Normal judgment mode>
First, the normal determination mode will be described with reference to FIG. In the normal determination mode, the signal processing unit (13) executes a sudden change determination process according to the presence or absence of coarse movement of the patient (P1).

<Step (ST101, ST102)>
First, the signal processing unit (13) takes in the signal level value of the body motion signal from the signal generation unit (12) (step (ST101)). Next, the signal processing unit (13) takes in the signal level value of the body motion signal at the next time from the signal generation unit (12) as “the signal level value of the current time of the body motion signal” (step (ST102)). . The signal processing unit (13) uses the signal level value of the body motion signal captured in the previous process (that is, the signal level value at the time immediately before the current time) as “the signal at the previous time of the body motion signal. Accumulated as “level value”.

<Step (ST103, ST104, ST105)>
Next, the signal processing unit (13) determines the presence or absence of coarse movement of the patient (P1) at the current time based on the signal level value at the current time of the body movement signal (step (ST103)). Specifically, when the signal level value (preferably absolute value) of the body motion signal at the current time is larger than the coarse motion determination threshold, the signal processing unit (13) ). When it is determined that there is coarse movement of the patient (P1) at the current time, the signal processing unit (13) stops the sudden change determination process (step (ST104)). When the monitoring of the patient (P1) is continued (“NO” in step (ST105)), the process proceeds to step (ST102).

<Step (ST106, ST107)>
On the other hand, if it is determined in step (ST103) that there is no coarse movement of the patient (P1) at the current time, the signal processing unit (13) determines the patient at the previous time based on the signal level of the previous time of the body movement signal. The presence / absence of coarse movement in (P1) is determined (step (ST106)). When it is determined that there is no coarse movement of the patient (P1) at the previous time, the signal processing unit (13) executes a sudden change determination process (step (ST107)). Then, the process proceeds to step (ST105). The sudden change determination process in step (ST107) will be described in detail later with reference to FIG.

<Step (ST108)>
On the other hand, if it is determined in step (ST106) that there is coarse movement of the patient (P1) at the previous time, the signal processing unit (13), based on the signal level value of the body movement signal at the current time, Determine whether the patient (P1) is moving. Specifically, when the signal level value (preferably absolute value) of the body movement signal at the current time is larger than the absence determination threshold, the signal processing unit (13) It is determined that there is body movement. That is, in step (ST108), the signal processing unit (13) determines the presence or absence of body movement of the patient (P1) after the coarse movement of the patient (P1) based on the body movement signal. If it is determined that there is body movement of the patient (P1) at the current time (ie, there is body movement of the patient (P1) after the coarse movement of the patient (P1)), the process proceeds to step (ST201) in FIG. . As a result, the determination mode of the signal processing unit (13) shifts from the normal determination mode (FIG. 18) to the irregular determination mode (FIG. 19). On the other hand, when it is determined that there is no body movement of the patient (P1) at the current time (that is, there is no body movement of the patient (P1) after the coarse movement of the patient (P1)), step (ST301) in FIG. Proceed to Thereby, the determination mode of the signal processing unit (13) shifts from the normal determination mode (FIG. 18) to the determination standby mode (FIG. 20).

<Anomaly judgment mode>
Next, the irregular determination mode will be described with reference to FIG. In the irregular determination mode, when the signal processing unit (13) detects that the patient (P1) has body movement after the coarse movement of the patient (P1) based on the body movement signal, the determination criterion (patient ( P1) is changed from the normal standard (first standard) to the irregular standard (second standard).

《Normal standard and irregular standard》
The normal criterion corresponds to the state of life activity of the patient (P1) at rest, and the anomaly criterion corresponds to the state of life activity after the coarse movement of the patient (P1). For example, a criterion threshold (specifically, a threshold relating to respiratory rate, heart rate, respiratory amplitude, heartbeat amplitude, etc.) set as an irregular criterion in the irregular determination mode is higher than a criterion threshold set as a normal criterion. It is preferable that it is increased by an amount corresponding to the increase amount of the biological activity accompanying the coarse movement of the patient (P1) (specifically, the respiration rate, heart rate, respiration amplitude, increase amount of the heart rate amplitude, etc.). Or, the criterion range (specifically, the range related to respiratory rate, heart rate, respiratory amplitude, heart rate amplitude, etc.) set as the irregular criterion in the irregular criterion mode is more than the criterion range set as the normal criterion. It is preferable that the amount is increased by an amount corresponding to the amount of increase in biological activity associated with coarse movement of the patient (P1) (specifically, the respiration rate, heart rate, respiration amplitude, increase amount of heart rate amplitude, etc.).

<< Step (ST201, ST202, ST203, ST204) >>
First, the signal processing unit (13) changes the criterion in the sudden change determination process from the normal criterion to the irregular criterion (step (ST201)). Then, the signal processing unit (13) starts measuring the elapsed time (that is, the elapsed time since the detection of the coarse motion of the patient (P1)) (step (ST202)). Next, the signal processing unit (13) executes a sudden change determination process based on the changed determination criterion (that is, the irregular criterion) (step (ST203)). When the monitoring of the patient (P1) is continued (“NO” in step (ST205)), the process proceeds to step (ST205). The sudden change determination process in step (ST203) will be described in detail later with reference to FIG.

<Step (ST205)>
Next, the signal processing unit (13) arrives at a predetermined return time when the elapsed time (ie, the elapsed time since the detection of the coarse motion of the patient (P1)) is started in step (ST202). It is determined whether or not. The return time is set based on the period (variation period) required for the patient (P1) 's life activity to return from the fluctuation state (fluctuation state after coarse movement of the patient (P1)) to the resting state. . If it is determined that the elapsed time has reached the return time, the process proceeds to step (ST102) in FIG. As a result, the determination mode of the signal processing unit (13) shifts from the irregular determination mode (FIG. 19) to the normal determination mode (FIG. 18).

《Step (ST206)》
On the other hand, if it is determined in step (ST205) that the elapsed time has not reached the return time, the signal processing unit (13) causes the elapsed time so that the criterion in the sudden change determination process returns from the irregular criterion to the normal criterion. In other words, the criterion for the sudden change determination process is corrected based on (that is, the elapsed time since the detection of the body movement of the patient (P1)). For example, the signal processing unit (13) is configured so that the criterion changes linearly (or exponentially) from the irregular criterion to the normal criterion according to the elapsed time from the detection of the patient's (P1) body movement. Correction of the criterion (for example, reduction of the criterion threshold or reduction of the criterion range) may be performed. Alternatively, the signal processing unit (13) maintains the criterion as an irregular criterion until the elapsed time reaches the return time, and switches the criterion from the irregular criterion to the normal criterion when the elapsed time reaches the recovery time. Also good.

<< Step (ST207, ST208, ST209, ST210) >>
Next, the signal processing unit (13) captures the signal level value of the body motion signal at the next time from the signal generation unit (12) as “the signal level value of the current time of the body motion signal” (step (ST207)). . Next, the signal processing unit (13) determines the presence or absence of coarse movement of the patient (P1) at the current time based on the signal level value at the current time of the body movement signal (step (ST208)). If it is determined that there is no coarse movement of the patient (P1) at the current time, the process proceeds to step (ST203). On the other hand, when it is determined that there is a rough movement of the patient (P1) at the current time, the signal processing unit (13) stops the sudden change determination process (step (ST209)). When the monitoring of the patient (P1) is continued (“NO” in step (ST210)), the process proceeds to step (ST102) in FIG. As a result, the determination mode of the signal processing unit (13) shifts from the irregular determination mode (FIG. 19) to the normal determination mode (FIG. 18).

<Judgment standby mode>
Next, the determination standby mode will be described with reference to FIG. In the determination standby mode, when the signal processing unit (13) detects that there is no body movement of the patient (P1) after the coarse movement of the patient (P1) based on the body movement signal, the sudden change determination process is stopped.

<Step (ST301, ST302)>
First, the signal processing unit (13) stops the sudden change determination process (step (ST301)). When the monitoring of the patient (P1) is continued (“NO” in step (ST302)), the process proceeds to step (ST303).

<Step (ST303, ST304, ST305, ST306)>
Next, the signal processing unit (13) takes in the signal level value of the body motion signal at the next time from the signal generation unit (102) as “the signal level value of the current time of the body motion signal” (step (ST303)). . Next, the signal processing unit (13) determines the presence or absence of coarse movement of the patient (P1) at the current time based on the signal level value at the current time of the body movement signal (step (ST304)). If it is determined that there is no coarse movement of the patient (P1) at the current time, the process proceeds to step (ST301). On the other hand, when it is determined that there is a rough movement of the patient (P1) at the current time, the signal processing unit (13) stops the sudden change determination process (step (ST305)). When the monitoring of the patient (P1) is continued (“NO” in step (ST306)), the process proceeds to step (ST102) in FIG. Thereby, the determination mode of the signal processing unit (13) shifts from the determination standby mode (FIG. 20) to the normal determination mode (FIG. 18).

<Abrupt change judgment processing>
Next, the sudden change determination process executed in step (ST107) in FIG. 18 and step (ST203) in FIG. 19 will be described with reference to FIG. In the following description, it is assumed that the count value (n) indicating the accumulated number of signal level values of the respiratory signal (or heartbeat signal) is set to an initial value (zero). The predetermined value (MAX) corresponds to the number of signal level values necessary for executing the sudden change determination process.

<Step (ST11, ST12, ST13, ST14)>
First, the signal processing unit (13) takes in the signal level value at the current time of the respiratory signal (or heartbeat signal) from the signal generation unit (12) (step (ST11)), and sets the count value (n) to “1”. Are added (step (ST12)). Next, the signal processing unit (13) determines whether or not the count value (n) has reached a predetermined value (MAX) (step (ST13)). If it is determined that the count value (n) has not reached the predetermined value (MAX), the sudden change determination process ends. On the other hand, when it is determined that the count value (n) has reached the predetermined value (MAX), the signal processing unit (13) sets the signal level value of the accumulated respiratory signal (or heartbeat signal) in advance. The sudden change determination process is started based on the determined determination standard (step (ST14)).

<Step (ST15, ST16, ST17, ST18)>
Next, the signal processing unit (13) determines whether or not the criterion for the sudden change determination process is satisfied based on the signal level value of the accumulated respiratory signal (or heartbeat signal) (step (ST15)). ). When the signal processing unit (13) determines that the determination criterion in the sudden change determination process is satisfied, the signal processing unit (13) outputs a determination result indicating that the state of the biological activity of the patient (P1) is suddenly changed (step S1). (ST16)), if it is determined that the criteria in the sudden change determination process are not satisfied, the determination result indicating that the state of life activity of the patient (P1) has not changed suddenly (or is stable) Is output (step (ST17)). Then, the signal processing unit (13) sets the count value to the initial value (zero) (step ST18) and ends the sudden change determination process.

<Stopping sudden change determination processing>
When the signal processing unit (13) stops the sudden change determination process (step (ST104, ST209, ST301, ST305, etc.)), the signal processing unit (13) discards the signal level value accumulated as a target of the sudden change determination process and counts ( Set the initial value (n) of n).

<Effects of Embodiment 2>
As described above, the presence or absence of coarse movement of the patient (P1) is detected based on the body movement signal, and the sudden change determination process is executed according to the presence or absence of the coarse movement of the patient (P1). Sudden change determination processing can be executed in consideration of changes in the monitoring status associated with coarse movement (for example, the presence or absence of the patient (P1) at the monitoring location (B), the change in the state of life activity of the patient (P1), etc.) . This makes it possible to accurately determine the presence or absence of a sudden change in the state of life of the patient (P1), so that the balance between reducing the processing burden of the information generation process and improving the real-time display of biological information is automatically adjusted appropriately. can do.

《Effects regarding judgment standby mode》
Specifically, the period when there is no patient (P1) in the bedding (B) by stopping the sudden change determination process when it is detected that there is no body movement of the patient (P1) after the coarse movement of the patient (P1) ( In the absence period), the sudden change determination process can be stopped. As a result, misjudgment during the absence period can be prevented, and therefore the presence or absence of a sudden change in the state of life activity of the patient (P1) can be accurately determined.

《Effects related to irregular judgment mode》
Furthermore, when it is detected that there is body movement of the patient (P1) after the coarse movement of the patient (P1), the judgment standard in the sudden change judgment processing corresponds to the normal standard (the state of life activity of the patient (P1) at rest) To change to anomalous criteria (standards corresponding to the state of life activity after coarse movement of the patient (P1)), when the patient (P1) is moving in the bedding (B), sudden change determination processing Can be set to an irregular standard (that is, a standard corresponding to the state of life activity after coarse movement of the patient (P1)). As a result, it is possible to execute the sudden change determination process in consideration of the state change of the biological activity due to the coarse movement of the patient (P1), so that the presence or absence of the sudden change in the state of the biological activity of the patient (P1) can be accurately determined. Can do.

  In addition, by correcting the criteria based on the elapsed time from the detection of coarse motion of the patient (P1) so that the criteria in the sudden change judgment process returns from the anomaly criteria to the normal criteria, the life activity of the patient (P1) It is possible to correct the determination criterion in the sudden change determination process based on the progress until the state returns from the fluctuation state to the resting state. As a result, it is possible to execute a sudden change determination process in consideration of the return from the fluctuation state of the patient's (P1) life activity to the resting state, so it is possible to accurately determine whether there is a sudden change in the life state of the patient (P1) can do.

<Setting of irregular standard and recovery time>
The irregular reference (specifically, the determination reference threshold or the determination reference range set as the irregular reference) may be a fixed value or a variable value. Further, the anomaly criterion may be set according to the magnitude of coarse movement of the patient (P1) (or the number of occurrences of coarse movement of the patient (P1)). For example, adjust the anomaly criterion so that the increase in the anomaly criterion with respect to the normal criterion increases as the coarse motion of the patient (P1) increases (that is, the amplitude of the body motion signal becomes larger than the coarse motion determination threshold). Also good. Alternatively, the anomaly criterion may be adjusted such that the amount of increase in the anomaly criterion relative to the normal criterion increases as the number of occurrences of coarse movement of the patient (P1) within a predetermined period increases.

  Similarly to the anomaly criterion, the return time compared with the elapsed time in the step (ST205) of the anomaly determination mode (FIG. 17) may be a fixed value or a variable value. Further, the return time may be set according to the magnitude of coarse movement of the patient (P1) (or the number of occurrences of coarse movement of the patient (P1)).

<Specific examples of irregular standards>
Next, a specific example of the irregular criterion corresponding to the specific example of the sudden change determination process will be described.

<< Specific Example of Anomaly Standard 1: Chain Stokes Breathing >>
When “Chain Stokes Respiration” as shown in FIG. 9 is a target of sudden change determination processing, the determination reference threshold value (threshold value related to the fluctuation amount of the envelope of the respiration signal) set as an irregular reference in the irregular determination mode is a normal reference. It is preferably set to be larger by a predetermined amount (for example, an amount corresponding to an increase in respiratory amplitude accompanying the coarse movement of the patient (P1)) than the set determination reference threshold.

<< Example of anomalous standards 2: Bio-breathing >>
When “bio-breathing” as shown in FIG. 10 is a target of a sudden change determination process, a determination reference threshold value set as an irregular reference in the irregular determination mode (a threshold value related to a dispersion value of a period length and a threshold value related to a dispersion value of an amplitude) ) Is preferably set to be larger than a determination reference threshold set as a normal reference by a predetermined amount (for example, an amount corresponding to an increase in respiratory amplitude associated with coarse movement of the patient (P1)). .

<< Example 3 of anomalous criteria: gradual decrease in breathing / gradual decrease in heart rate >>
In the case where “respiratory gradual decrease” (or “heart rate gradual decrease”) as shown in FIG. 11 is a target of the sudden change determination process, a determination reference threshold (respiration signal (or heart rate signal)) set as an irregular reference in the irregular determination mode. The threshold for the amount of slope of the time-varying straight line) depends on the amount of increase in respiratory amplitude (or heartbeat amplitude) associated with coarse movement of the patient (P1) rather than the criterion threshold set as the normal reference The amount is preferably set to be larger by (amount).

<< Specific example 4 of irregular standard: gradual decrease in respiratory rate / gradual decrease in heart rate >>
In addition, when “gradual decrease in respiratory rate” (or “gradual decrease in heart rate”) is the target of a sudden change determination process, the time of a determination reference threshold (respiration rate (or heart rate)) set as an irregular reference in the irregular determination mode The threshold for the slope of the change line is an amount that corresponds to the increase in the respiration rate (or heart rate) that accompanies the coarse movement of the patient (P1), rather than the criterion threshold that is set as the normal reference. ) Is preferably set to be larger.

<< Example 5 of anomalous criteria: apnea / cardiac arrest >>
When “apnea” (or “cardiac arrest”) as shown in FIG. 12 is a target of sudden change determination processing, a determination reference threshold (respiration signal (or heart rate signal)) set as an irregular reference in the irregular determination mode. The threshold for the envelope signal level) is a predetermined amount (for example, the amount corresponding to the increase in respiratory amplitude (or heartbeat amplitude) associated with coarse movement of the patient (P1) than the criterion threshold set as the standard. ) Is preferably set to be larger.

<< Example 6 of irregular standard: Abnormal respiratory rate / abnormal heart rate >>
In addition, when “abnormal respiratory rate” (or “abnormal heart rate”) is the target of the sudden change determination process, the determination reference range (respiratory rate (or heart rate) range set as an irregular reference in the irregular determination mode) ) Is set to be wider by a predetermined amount (for example, an amount corresponding to the increase in respiratory rate (or heart rate) associated with coarse movement of the patient (P1)) than the criterion range set as the normal reference It is preferable that

<Modification 1 of determination operation by signal processing unit>
Of the determination modes (normal determination mode, irregular determination mode, determination standby mode) of the signal processing unit (13), the irregular determination mode (FIG. 19) may be omitted. In this case, if it is determined in step (ST108) in FIG. 18 that there is a body movement of the patient (P1) at the current time (“YES” in step (ST108)), the process proceeds to step (ST107). . That is, the signal processing unit (13) determines that the patient (P1) has a body movement after the coarse movement of the patient (P1) based on the body movement signal, without shifting to the irregular determination mode. It may be configured to execute the sudden change determination process while keeping the reference as a normal reference.

  Even when configured as described above, the sudden change determination process can be stopped when it is detected that there is no body movement of the patient (P1) after the coarse movement of the patient (P1). It is possible to stop the abrupt change determination process during a period when P1) is absent (absence period).

<Modification 2 of determination operation by signal processing unit>
Further, the determination standby mode (FIG. 20) may be omitted from the determination modes (normal determination mode, irregular determination mode, determination standby mode) of the signal processing unit (13). In this case, step (ST108) is omitted in the normal determination mode (FIG. 18), and “YES” in step (ST106) is determined in step (ST106) that there is rough movement of the patient (P1) at the previous time. ) Goes to step (ST201) in FIG. That is, when the signal processing unit (13) detects the coarse motion of the patient (P1) based on the body motion signal, the criterion for the sudden change determination process is changed from the normal criterion (first criterion) to the irregular criterion (second criterion). ) May be configured to be changed.

  By configuring as described above, when there is coarse movement of the patient (P1), the determination standard in the sudden change determination process corresponds to the irregular standard (that is, the state of life activity after the rough movement of the patient (P1)). Standard). As a result, it is possible to execute the sudden change determination process in consideration of the state change of the biological activity accompanying the coarse movement of the patient (P1).

<Modification 3 of determination operation by signal processor (determination interruption mode)>
Further, the signal processing unit (13) may have a determination interruption mode (FIG. 22) instead of the irregular determination mode (FIG. 19) in the determination mode (normal determination mode, irregular determination mode, determination standby mode). good. In the determination interruption mode shown in FIG. 22, the steps (ST201, ST206) shown in FIG. 19 are omitted, and step (ST401) (processing for stopping the sudden change determination process) instead of the step (ST203) shown in FIG. Is executed. That is, when the signal processing unit (13) detects that there is body movement of the patient (P1) after the coarse movement of the patient (P1) based on the body movement signal, the signal processing unit (13) determines in advance from detection of the coarse movement of the patient (P1). The abrupt change determination process is stopped during a period until the set return time elapses. Note that the recovery time is set based on the period (variation period) required for the patient (P1) to change to a resting state after the patient's (P1) biological activity state has changed due to the coarse movement of the patient (P1). ing.

  By configuring as described above, the sudden change determination process can be stopped in the period (variation period) until the biological activity of the patient (P1) returns from the fluctuation state to the resting state. As a result, it is possible to prevent erroneous determination during the fluctuation period of the life activity of the patient (P1), and therefore it is possible to accurately determine whether there is a sudden change in the state of the life activity of the patient (P1).

<Modification 4 of determination operation by signal processing unit>
Of the determination modes (normal determination mode, determination interruption mode, determination standby mode) of the signal processing unit (13), the determination standby mode (FIG. 20) may be omitted. In this case, step (ST108) is omitted in the normal determination mode (FIG. 18), and “YES” in step (ST106) is determined in step (ST106) that there is rough movement of the patient (P1) at the previous time. ) Goes to step (ST202) in FIG. That is, when the signal processing unit (13) detects the coarse movement of the patient (P1) based on the body movement signal, the signal processing unit (13) performs the sudden change determination process in the period from the detection of the coarse movement of the patient (P1) until the return time elapses. It may be configured to stop.

  Even when configured as described above, the sudden change determination process can be stopped in the period (fluctuation period) until the patient's (P1) life activity returns from the fluctuation state to the resting state. It is possible to prevent misjudgment during the activity fluctuation period.

<Operation during absence period>
Note that the signal processing unit (13) may be configured to stop the information generation process in a period (absence period) in which the patient (P1) is away from the bedding (B). For example, the signal processing unit (13) stops the information generation process when the determination mode is the determination standby mode (FIG. 20). With this configuration, the processing load of the information generation process can be further reduced. In this case, the signal processing unit (13) is configured to generate notification information indicating that the patient (P1) is away from the bedding (B) and supply the notification information to the biological information notification unit (14). May be. By comprising in this way, it can notify that a patient (P1) has left | separated from bedding (B).

(Embodiment 3)
FIG. 23 shows a configuration example of the biological monitoring system (1) according to the third embodiment. In this biological monitoring system (1), the signal processing unit (13) includes a signal transmission unit (301) and a signal reception unit (302). Other configurations are the same as those shown in FIG. In this example, the signal transmission unit (301) is provided in the main body unit (21) of the unconstrained sensor (20), and the signal reception unit (302) and the biological information notification unit (14) are connected to the monitoring information terminal (30). ). For example, the monitoring information terminal (30) is configured by a portable information terminal such as a mobile phone, a personal computer, or the like.

  In this example, the non-restraining sensor (20) is arranged in the home of the patient (P1). The monitoring information terminal (30) is arranged in a hospital located away from the home of the patient (P1) and is operated by a doctor (P2).

<Signal transmitter>
The signal transmission unit (301) performs processing (signal transmission processing) for transmitting the generation signals (body motion signal, respiration signal, and heartbeat signal) generated by the signal generation unit (12) based on a predetermined execution cycle. Repeatedly. The signal transmission unit (301) is configured to be able to change the execution cycle of the signal transmission process. For example, the signal transmission unit (301) includes a transmission interface circuit, a CPU, a memory, and the like provided in the main unit (21).

  Further, in this example, the signal transmission unit (301) generates a biological signal generated by the signal generation unit (12) (specifically, at least one of a body motion signal, a respiratory signal, and a heartbeat signal). Based on this, a process of determining whether there is a sudden change in the state of life of the patient (P1) (abrupt change determination process) is executed. Note that the signal transmission unit (301) may execute the sudden change determination process according to the presence or absence of coarse movement of the patient (P1) (see FIGS. 18 to 22). Further, the signal generation unit (13) executes a process (period control process: FIG. 8) for controlling the execution period of the signal transmission process according to the determination result of the sudden change determination process.

<Signal receiver>
The signal receiving unit (302) is configured to receive a biological signal (body motion signal, respiratory signal, and heartbeat signal) periodically transmitted from the signal transmitting unit (301) (signal receiving process) and a signal receiving process. A process (information generation process) for generating biological information based on the received biological signal (body motion signal, respiratory signal, and heartbeat signal) is executed. For example, the signal receiving unit (302) includes a reception interface circuit, a CPU, a memory, and the like provided in the monitoring information terminal (30).

<Repeat execution of signal transmission processing>
Next, the repeated execution of the signal transmission process will be described with reference to FIG. First, the signal processing unit (13) takes in a biological signal (body motion signal, respiration signal, and heart rate signal) to be subjected to information generation processing from the signal generation unit (12) (step (ST21)). Next, the signal processing unit (13) transmits a biological signal (step (ST32)). At this time, the signal processing unit (13) starts measuring the elapsed time from the transmission of the biological signal. When the monitoring of the patient (P1) is continued (“NO” in step (ST23)), the signal processing unit (13) determines whether the elapsed time from the transmission of the biological signal has reached the execution cycle. (Step (ST24)). When the elapsed time from the transmission of the biological signal reaches the execution cycle (that is, when the execution cycle has elapsed from the transmission of the biological signal), the signal processing unit (13) The body motion signal, the respiration signal, and the heartbeat signal) are captured from the signal generation unit (12) (step (ST21)). Thus, when the execution cycle of the signal transmission process in the signal transmission unit (301) is changed, the execution cycle of the information generation process in the signal reception unit (302) is changed. As a result, the biological information notification unit (14) The update period of the biometric information is changed.

<Effects of Embodiment 3>
As described above, by generating biological information based on the biological signal transmitted from the signal transmission unit (301) to the signal receiving unit (302) and supplying the biological information to the biological information notification unit (14), the patient (P1) Biological information about the patient (P1) can be provided to the doctor (P2) who is away from the patient. Thereby, monitoring of the patient (P1) by the doctor (P2) at a place away from the patient (P1) can be supported.

  In addition, by changing the signal transmission processing execution cycle in the signal transmission unit (301) according to the determination result of the sudden change determination processing, the pause time of the signal transmission processing is changed according to the state of life activity of the patient (P1) can do. For example, when the state of the biological activity of the patient (P1) is stable (that is, when the necessity for monitoring the patient (P1) is low), the execution cycle of the signal transmission process is a long cycle (first cycle) By setting to, the pause time of the signal transmission process can be extended. Thereby, the amount of communication between the signal transmission unit (301) and the signal reception unit (302) can be reduced.

<Modification of signal transmission processing by signal transmitter>
The signal transmission unit (301) transmits the biological signal by the first signal transmission process when the execution period of the signal transmission process is set to the long period (first period), and the information generation process When the execution cycle is set to a short cycle (second cycle), the biological signal may be transmitted by the second signal transmission process. Note that the information amount of the biological signal transmitted by the first signal transmission process is smaller than the information amount of the biological signal transmitted by the second signal transmission process. For example, in the first signal transmission process, thinning or averaging of biological signals is performed.

  By configuring as described above, the amount of information (communication amount) of the biological signal transmitted from the signal transmission unit (301) to the signal reception unit (302) can be changed according to the determination result of the sudden change determination process. . For example, when the execution cycle of the information generation process is set to a long cycle, the communication amount can be reduced, so that the processing load of the information generation process can be reduced. On the other hand, when the execution cycle of the information generation process is set to a short cycle, the amount of communication can be increased, so that detailed biological information can be displayed. Thus, since the amount of information (communication amount) of the biological signal transmitted from the signal transmission unit (301) to the signal reception unit (302) can be changed according to the determination result of the sudden change determination process, the patient (P1 ), The amount of communication can be further reduced.

  Furthermore, when the signal transmission process (13) switches the execution period of the signal transmission process from the long period (first period) to the short period (second period), the biological activity of the patient (P1) in the sudden change determination process The biological signal in the period before the sudden change (the time associated with the biological signal) before the time when it is determined that there is a sudden state change may be transmitted by the second signal transmission process.

  By configuring as described above, detailed biological information about the state of life activity of the patient (P1) before the sudden change of state can be generated, so that the doctor (P2) supports the judgment of the state of the patient (P1). be able to. Thereby, the burden of monitoring by the doctor (P2) can be reduced.

(Embodiment 4)
FIG. 25 shows a configuration example of the biological monitoring system (1) according to the fourth embodiment. This biological monitoring system (1) includes an operation unit (15) in addition to the configuration shown in FIG. Moreover, in this example, the operation part (15) is provided in the main body unit (21) of the non-restraining sensor (20).

<Operation unit>
The operation unit (15) is operated by the doctor (P2), and is cycle information regarding the execution cycle (for example, cycle information indicating one of the long cycle (first cycle) and the short cycle (second cycle)). Is entered. For example, the operation unit (15) is configured by an input mechanism (touch panel, operation button, etc.) provided in the main unit (21).

<Signal processing section>
The signal processing unit (13) generates biological information related to the biological activity of the patient (P1) based on the biological signals (body motion signal, respiratory signal, and heartbeat signal) generated by the signal generation unit (12) ( Information generation processing: FIG. 7) is repeatedly executed based on a predetermined execution cycle. The signal processing unit (13) is configured to be able to change the execution cycle of the information generation process.

  Further, in this example, the signal processing unit (13) executes a process (period control process) for changing the execution period of the information generation process based on the period information given to the operation unit (15).

<Effects of Embodiment 4>
As described above, since the execution cycle of the information generation process can be changed by the operation of the doctor (P2), the processing load of the information generation process can be reduced and the biological information can be displayed in real time according to the request of the doctor (P2) The balance with improvement can be adjusted.

(Embodiment 5)
FIG. 26 shows a configuration example of the biological monitoring system (1) according to the fifth embodiment. This biological monitoring system (1) includes a period information transmitting unit (16) and a period information receiving unit (17) in addition to the configuration shown in FIG. The signal processing unit (13) includes a signal transmission unit (301) and a signal reception unit (302). In this example, the signal transmission unit (301) and the period information reception unit (17) are provided in the main body unit (21) of the unconstrained sensor (20). The signal reception unit (302), the biological information notification unit (14), the operation unit (15), and the cycle information transmission unit (16) are provided in the monitoring information terminal (30). For example, the monitoring information terminal (30) is configured by a portable information terminal such as a mobile phone, a personal computer, or the like.

  In this example, the non-restraining sensor (20) is arranged in the home of the patient (P1). The monitoring information terminal (30) is arranged in a hospital located away from the home of the patient (P1) and is operated by a doctor (P2).

<Period information transmitter>
The cycle information transmission unit (16) transmits the cycle information given to the operation unit (15). For example, the cycle information transmission unit (16) includes a transmission interface circuit, a CPU, a memory, and the like provided in the monitoring information terminal (30).

<Period information receiver>
The period information receiving unit (17) receives the period information transmitted from the period information transmitting unit (16). For example, the period information receiving unit (17) includes a reception interface circuit, a CPU, a memory, and the like provided in the main unit (21).

<Signal transmitter>
The signal transmission unit (301) performs processing (signal transmission processing) for transmitting the biological signal (body motion signal, respiratory signal, and heartbeat signal) generated by the signal generation unit (12) based on a predetermined execution cycle. Repeatedly. The signal transmission unit (301) is configured to be able to change the execution cycle of the signal transmission process.

  Further, in this example, the signal transmission unit (301) executes a process (period control process) for changing the execution period based on the period information received by the period reception unit (17).

<Signal receiver>
The signal receiving unit (302) is configured to receive a biological signal (body motion signal, respiratory signal, and heartbeat signal) periodically transmitted from the signal transmitting unit (301) (signal receiving process) and a signal receiving process. A process (information generation process) for generating biological information based on the received biological signal (body motion signal, respiratory signal, and heartbeat signal) is executed.

  By changing the execution cycle of the signal transmission process in the signal transmission unit (301), the execution cycle of the information generation process in the signal reception unit (302) is changed. As a result, the biological information in the biological information notification unit (14) is changed. The update cycle is changed.

<Effects of Embodiment 5>
As described above, by generating biological information based on the biological signal transmitted from the signal transmission unit (301) to the signal receiving unit (302) and supplying the biological information to the biological information notification unit (14), the patient (P1) Biological information about the patient (P1) can be provided to the doctor (P2) who is away from the patient. Thereby, monitoring of the patient (P1) by the doctor (P2) at a place away from the patient (P1) can be supported.

  In addition, by supplying the period information given to the operation unit (15) by the doctor (P2) to the signal transmission unit (301) via the period information transmission unit (16) and the period information reception unit (17), The execution cycle of the signal transmission process can be changed by the operation of the doctor (P2) located away from the patient (P1).

  Furthermore, since the pause time of the signal transmission process can be changed based on the period information given to the operation unit (15) by the doctor (P2), the signal transmission unit (301) can be changed according to the request of the doctor (P2). And the signal reception unit (302) can be reduced.

(Other embodiments)
In the above embodiment, the case where the living body (P1) to be monitored is “patient” has been described as an example, but the living body (P1) is not limited to a human but may be an animal. Moreover, although the case where the supervisor (P2) of the living body (P1) is “doctor” is described as an example, the supervisor (P2) is a person other than the doctor (for example, nurse, pharmacist, caregiver, The patient's family).

  Moreover, you may implement combining the above embodiment suitably. The above embodiments are essentially preferable examples, and are not intended to limit the scope of the present invention, its application, or its use.

  As described above, the above-described living body monitoring system is useful as a medical system that monitors the state of life activity of a patient.

1 Biological monitoring system 11 Pressure sensitive unit (pressure sensitive part)
DESCRIPTION OF SYMBOLS 12 Signal generation part 13 Signal processing part 14 Biological information notification part 15 Operation part 16 Period information transmission part 17 Period information reception part 20 Unconstrained sensor 21 Main body unit 30 Monitoring information terminal 201 Pressure receiving part 202 Extraction part 301 Signal transmission part 302 Signal Receiver P1 Patient (living body)
P2 Doctor (Monitor)

Claims (16)

A tubular pressure-sensitive part (11) that is installed in a predetermined monitoring place (B) and on which a pressure associated with body movement of the living body (P1) in the monitoring place (B) acts;
A signal generation unit (12) that generates a biological signal based on an internal pressure change of the pressure sensing unit (11);
Based on a biological signal generated by the signal generator (12), the information generation processing for generating biological information related to the biological activity of the biological body (P1) is repeatedly executed based on a predetermined execution cycle, A signal processing unit (13) configured to be able to change the execution cycle;
A living body monitoring system comprising: a living body information notifying unit (14) for displaying living body information generated by the signal processing unit (13). In claim 1,
The signal processor (13)
A sudden change determination process for determining the presence or absence of a sudden change in the state of life of the living body (P1) based on the biological signal generated by the signal generation unit (12);
When it is determined in the sudden change determination process that there is no sudden change in the state of the biological activity of the living body (P1), the execution cycle is set to the first period, and the biological activity of the living body (P1) is set in the sudden change determination process And a periodic control process for setting the execution period to a second period shorter than the first period when it is determined that there is a sudden change in the state of the living body. Monitoring system. In claim 2,
When the execution cycle of the information generation process is set to the first cycle, the signal processing unit (13) performs the first information generation process on the biological signal to obtain the first biological information. And when the execution cycle of the information generation process is set to the second period, the second biological information is generated by performing the second information generation process on the biological signal. ,
The processing burden of the first information generation process is less than the processing burden of the second information generation process,
The biological monitoring system, wherein the information amount of the first biological information is smaller than the information amount of the second biological information. In claim 3,
When the signal generation unit (13) switches the execution cycle of the information generation processing from the first cycle to the second cycle, the sudden change determination processing causes a sudden change in the state of the biological activity of the living body (P1). A biological monitoring system configured to generate the second biological information based on the biological signal in a period before a sudden change before a time when it is determined to be present. In any one of Claims 2-4,
The biological signal includes a body motion signal including a coarse motion component derived from the coarse motion of the biological body (P1), a respiratory signal derived from the breathing of the biological body (P1), and a heartbeat derived from the heartbeat of the biological body (P1). Including at least the body movement signal among the signals,
The signal processing unit (13) detects the presence or absence of rough movement of the living body (P1) based on the body movement signal, and executes the sudden change determination process according to the presence or absence of rough movement of the living body (P1). A biological monitoring system configured as described above. In claim 5,
The signal processing unit (13) is configured to stop the sudden change determination process when detecting that there is no body movement of the living body (P1) after the rough movement of the living body (P1) based on the body movement signal. A living body monitoring system characterized by that. In claim 6,
When the signal processing unit (13) detects that there is a body movement of the living body (P1) after the rough movement of the living body (P1) based on the body movement signal, in the sudden change determination process, the living body (P1) The determination criteria for determining the presence or absence of a sudden change in the state of the life activity of the living body (P1) from the first reference corresponding to the state of the life activity of the living body (P1) at rest, the life activity after the rough movement of the life (P1) It is comprised so that it may change to the 2nd reference | standard corresponding to the state of (2), The biological monitoring system characterized by the above-mentioned. In claim 5,
When the signal processing unit (13) detects coarse movement of the living body (P1) based on the body motion signal, the signal processing unit (13) determines whether or not there is a sudden change in the state of life of the living body (P1) in the sudden change determination process. Is changed from the first reference corresponding to the state of life activity of the living body (P1) at rest to the second reference corresponding to the state of life activity after the rough movement of the living body (P1). A biological monitoring system configured as described above. In claim 7 or 8,
The signal processing unit (13) is configured to determine whether the criterion in the sudden change determination process returns from the second criterion to the first criterion based on an elapsed time from the detection of the coarse movement of the living body (P1) A biological monitoring system configured to correct a determination criterion. In claim 5,
When the signal processing unit (13) detects the coarse movement of the living body (P1) based on the body movement signal, the signal processing unit (13) detects the rough movement of the living body (P1) until a predetermined return time elapses. A living body monitoring system configured to stop the sudden change determination process during a period. In any one of Claims 5-10,
The coarse motion determination threshold value for detecting the presence or absence of the coarse motion of the living body (P1) in the signal processing unit (13) is the respiratory signal and the heartbeat signal extracted when the living body (P1) is in a normal rest state. A living body monitoring system characterized in that the value is set to at least one of them. In any one of Claims 2-11,
The signal processor (13)
A signal transmission unit (301) that repeatedly executes a signal transmission process for transmitting a biological signal generated by the signal generation unit (12) based on the execution period, and that performs the sudden change determination process and the period control process; ,
A signal for executing a signal reception process for receiving a biological signal periodically transmitted from the signal transmission unit (301) and an information generation process for generating the biological information based on the biological signal received by the reception process A living body monitoring system including a receiving unit (302). In claim 12,
The signal transmission unit (301) transmits the biological signal by the first signal transmission process when the execution period of the signal transmission process is set to the first period, and performs the information generation process. When the execution cycle is set to the second cycle, the biological signal is transmitted by the second signal transmission process,
The biological monitoring system characterized in that the information amount of the biological signal transmitted by the first signal transmission process is smaller than the information amount of the biological signal transmitted by the second signal transmission process. In claim 13,
When the signal transmission unit (13) switches the execution cycle of the signal transmission process from the first cycle to the second cycle, the sudden change determination process causes a sudden change in the state of the biological activity of the living body (P1). A biological monitoring system configured to transmit, by the second signal transmission process, the biological signal in a period before a sudden change before a time when it is determined to be present. In claim 1,
It further includes an operation unit (15) that is operated by a supervisor (P2) and is provided with cycle information regarding the execution cycle,
The biological signal monitoring system, wherein the signal processing unit (13) is configured to execute a cycle control process for changing the execution cycle based on the cycle information given to the operation unit (15). . In claim 15,
A cycle information transmission unit (16) for transmitting the cycle information given to the operation unit (15);
A periodic information receiving unit (17) for receiving periodic information from the periodic information transmitting unit (16);
The signal processor (13)
The signal transmission processing for transmitting the biological signal generated by the signal generation unit (12) is repeatedly executed based on the execution cycle, and the execution cycle based on the cycle information received by the cycle reception unit (17). A signal transmission unit (301) that executes periodic control processing for changing
A signal reception process for receiving a biological signal periodically transmitted from the signal transmission unit (301) and an information generation process for generating the biological information based on the biological signal received by the signal reception process are executed. A biological monitoring system including a signal receiving unit (302).