JP2014129324A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014129324A5 JP2014129324A5 JP2013113125A JP2013113125A JP2014129324A5 JP 2014129324 A5 JP2014129324 A5 JP 2014129324A5 JP 2013113125 A JP2013113125 A JP 2013113125A JP 2013113125 A JP2013113125 A JP 2013113125A JP 2014129324 A5 JP2014129324 A5 JP 2014129324A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- liver
- maltitol
- oral
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 15
- 210000004185 Liver Anatomy 0.000 claims 6
- VQHSOMBJVWLPSR-WUJBLJFYSA-N Maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims 6
- 239000000845 maltitol Substances 0.000 claims 6
- 229940035436 maltitol Drugs 0.000 claims 6
- 235000010449 maltitol Nutrition 0.000 claims 6
- 239000004480 active ingredient Substances 0.000 claims 4
- 230000004064 dysfunction Effects 0.000 claims 3
- 240000007049 Juglans regia Species 0.000 claims 2
- 235000009496 Juglans regia Nutrition 0.000 claims 2
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 claims 2
- 240000004678 Panax pseudoginseng Species 0.000 claims 2
- 235000003140 Panax quinquefolius Nutrition 0.000 claims 2
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Resveratrol Natural products C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 claims 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N Taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 235000008434 ginseng Nutrition 0.000 claims 2
- 235000005035 ginseng Nutrition 0.000 claims 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 2
- 230000003908 liver function Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 235000020234 walnut Nutrition 0.000 claims 2
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims 1
- MQZIGYBFDRPAKN-QISQUURKSA-N 6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-(4-hydroxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethylcyclohex-2-en-1-one Chemical compound CC=1C(=O)C(O)CC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(=O)C(O)CC1(C)C MQZIGYBFDRPAKN-QISQUURKSA-N 0.000 claims 1
- 229960003767 Alanine Drugs 0.000 claims 1
- 208000007082 Alcoholic Fatty Liver Diseases 0.000 claims 1
- 102000015427 Angiotensins Human genes 0.000 claims 1
- 108010064733 Angiotensins Proteins 0.000 claims 1
- 240000002900 Arthrospira platensis Species 0.000 claims 1
- 235000016425 Arthrospira platensis Nutrition 0.000 claims 1
- 229960005261 Aspartic Acid Drugs 0.000 claims 1
- 210000004369 Blood Anatomy 0.000 claims 1
- 241000195649 Chlorella <Chlorellales> Species 0.000 claims 1
- 240000007154 Coffea arabica Species 0.000 claims 1
- 244000163122 Curcuma domestica Species 0.000 claims 1
- 235000003392 Curcuma domestica Nutrition 0.000 claims 1
- 240000008966 Cynara cardunculus Species 0.000 claims 1
- 235000019106 Cynara scolymus Nutrition 0.000 claims 1
- 229960002433 Cysteine Drugs 0.000 claims 1
- 206010016262 Fatty liver alcoholic Diseases 0.000 claims 1
- 229920000855 Fucoidan Polymers 0.000 claims 1
- 240000008397 Ganoderma lucidum Species 0.000 claims 1
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims 1
- 240000004670 Glycyrrhiza echinata Species 0.000 claims 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims 1
- LPLVUJXQOOQHMX-MYOOOWEVSA-N Glycyrrhizic acid Natural products O=C(O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@H](C(=O)O)O2)[C@@H](O[C@@H]2C(C)(C)[C@H]3[C@@](C)([C@H]4C(=O)C=C5[C@](C)([C@]4(C)CC3)CC[C@]3(C)[C@H]5C[C@](C(=O)O)(C)CC3)CC2)O1 LPLVUJXQOOQHMX-MYOOOWEVSA-N 0.000 claims 1
- 239000004378 Glycyrrhizin Substances 0.000 claims 1
- 102000004877 Insulin Human genes 0.000 claims 1
- 108090001061 Insulin Proteins 0.000 claims 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 1
- 229940078795 Lactoferrin Drugs 0.000 claims 1
- 102000010445 Lactoferrin Human genes 0.000 claims 1
- 108010063045 Lactoferrin Proteins 0.000 claims 1
- 229940067606 Lecithin Drugs 0.000 claims 1
- 229940010454 Licorice Drugs 0.000 claims 1
- AGBQKNBQESQNJD-SSDOTTSWSA-N Lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 claims 1
- 208000008338 Non-alcoholic Fatty Liver Disease Diseases 0.000 claims 1
- 206010053219 Non-alcoholic steatohepatitis Diseases 0.000 claims 1
- 229940041672 Oral Gel Drugs 0.000 claims 1
- 229960003104 Ornithine Drugs 0.000 claims 1
- 241000237502 Ostreidae Species 0.000 claims 1
- 241000282373 Panthera pardus Species 0.000 claims 1
- 240000003444 Paullinia cupana Species 0.000 claims 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N Raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 claims 1
- MUPFEKGTMRGPLJ-RMMQSMQOSA-N Raffinose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 MUPFEKGTMRGPLJ-RMMQSMQOSA-N 0.000 claims 1
- 240000000947 Rumex vesicarius Species 0.000 claims 1
- 229940081973 S-Adenosylmethionine Drugs 0.000 claims 1
- MEFKEPWMEQBLKI-AIRLBKTGSA-O S-adenosyl-L-methionine zwitterion Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H]([NH3+])C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-O 0.000 claims 1
- PEYUIKBAABKQKQ-AFHBHXEDSA-N Sesamin Chemical compound C1=C2OCOC2=CC([C@H]2OC[C@H]3[C@@H]2CO[C@@H]3C2=CC=C3OCOC3=C2)=C1 PEYUIKBAABKQKQ-AFHBHXEDSA-N 0.000 claims 1
- 240000003670 Sesamum indicum Species 0.000 claims 1
- 235000003434 Sesamum indicum Nutrition 0.000 claims 1
- 229940069764 Shark liver oil Drugs 0.000 claims 1
- SEBFKMXJBCUCAI-HKTJVKLFSA-N Silibinin Chemical compound C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC=C(C=C3O2)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-HKTJVKLFSA-N 0.000 claims 1
- 241000320380 Silybum Species 0.000 claims 1
- 235000010841 Silybum marianum Nutrition 0.000 claims 1
- 229940082787 Spirulina Drugs 0.000 claims 1
- 240000001949 Taraxacum officinale Species 0.000 claims 1
- 229960003080 Taurine Drugs 0.000 claims 1
- 235000001484 Trigonella foenum graecum Nutrition 0.000 claims 1
- 240000005216 Trigonella foenum-graecum Species 0.000 claims 1
- 240000006365 Vitis vinifera Species 0.000 claims 1
- 235000014787 Vitis vinifera Nutrition 0.000 claims 1
- 229960001570 ademetionine Drugs 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 230000001476 alcoholic Effects 0.000 claims 1
- 230000000111 anti-oxidant Effects 0.000 claims 1
- 239000003524 antilipemic agent Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 235000006708 antioxidants Nutrition 0.000 claims 1
- 235000016520 artichoke thistle Nutrition 0.000 claims 1
- 235000003704 aspartic acid Nutrition 0.000 claims 1
- 235000013793 astaxanthin Nutrition 0.000 claims 1
- 229940022405 astaxanthin Drugs 0.000 claims 1
- 239000001168 astaxanthin Substances 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 235000016213 coffee Nutrition 0.000 claims 1
- 235000013353 coffee beverage Nutrition 0.000 claims 1
- 235000003373 curcuma longa Nutrition 0.000 claims 1
- 235000015422 curly dock Nutrition 0.000 claims 1
- 235000015426 curly dock Nutrition 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- 235000009242 dandelion Nutrition 0.000 claims 1
- 235000014079 dandelion Nutrition 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 201000009846 fatty liver disease Diseases 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 235000020510 functional beverage Nutrition 0.000 claims 1
- 235000013376 functional food Nutrition 0.000 claims 1
- 229960004949 glycyrrhizic acid Drugs 0.000 claims 1
- 235000019410 glycyrrhizin Nutrition 0.000 claims 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 235000021242 lactoferrin Nutrition 0.000 claims 1
- 239000000787 lecithin Substances 0.000 claims 1
- 235000010445 lecithin Nutrition 0.000 claims 1
- 235000014063 licorice root Nutrition 0.000 claims 1
- 235000009408 lignans Nutrition 0.000 claims 1
- 229930013686 lignans Natural products 0.000 claims 1
- 235000019136 lipoic acid Nutrition 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 201000004044 liver cirrhosis Diseases 0.000 claims 1
- 201000009673 liver disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 235000012054 meals Nutrition 0.000 claims 1
- 235000001411 milk thistle Nutrition 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 239000002324 mouth wash Substances 0.000 claims 1
- -1 oral jelly Substances 0.000 claims 1
- 239000000668 oral spray Substances 0.000 claims 1
- 239000007935 oral tablet Substances 0.000 claims 1
- 235000020636 oyster Nutrition 0.000 claims 1
- 235000012361 paullinia cupana Nutrition 0.000 claims 1
- 229960001109 policosanol Drugs 0.000 claims 1
- 150000008442 polyphenolic compounds Chemical class 0.000 claims 1
- 235000013824 polyphenols Nutrition 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000002464 receptor antagonist Substances 0.000 claims 1
- 235000021283 resveratrol Nutrition 0.000 claims 1
- 229940016667 resveratrol Drugs 0.000 claims 1
- 229940109850 royal jelly Drugs 0.000 claims 1
- 231100000489 sensitizer Toxicity 0.000 claims 1
- 239000010686 shark liver oil Substances 0.000 claims 1
- 235000017700 silymarin Nutrition 0.000 claims 1
- 229960004245 silymarin Drugs 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 229960002663 thioctic acid Drugs 0.000 claims 1
- 235000001019 trigonella foenum-graecum Nutrition 0.000 claims 1
- 235000013976 turmeric Nutrition 0.000 claims 1
Claims (14)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013113125A JP6437183B2 (en) | 2012-11-30 | 2013-05-29 | Liver function improving agent |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012263134 | 2012-11-30 | ||
JP2012263134 | 2012-11-30 | ||
JP2013113125A JP6437183B2 (en) | 2012-11-30 | 2013-05-29 | Liver function improving agent |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2014129324A JP2014129324A (en) | 2014-07-10 |
JP2014129324A5 true JP2014129324A5 (en) | 2016-07-21 |
JP6437183B2 JP6437183B2 (en) | 2018-12-12 |
Family
ID=51408084
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013113125A Active JP6437183B2 (en) | 2012-11-30 | 2013-05-29 | Liver function improving agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP6437183B2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020209429A1 (en) * | 2019-04-12 | 2020-10-15 | 주식회사 비엔지삶 | Ginseng candy comprising bioactive components of palmyra palm and artichoke, and method of preparing same |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0399018A (en) * | 1989-09-11 | 1991-04-24 | Otsuka Pharmaceut Co Ltd | Agent for promoting secretion of glucagon-like peptide hormone |
JPH0753375A (en) * | 1993-08-10 | 1995-02-28 | Tooa Eiyoo Kk | Therapeutic agent for hepatopathy |
KR101356330B1 (en) * | 2004-12-24 | 2014-01-27 | 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 | Hepatic function remedial agent |
CN101410101A (en) * | 2006-03-31 | 2009-04-15 | 明治乳业株式会社 | Anti-fat-accumulation composition |
JP5041780B2 (en) * | 2006-10-23 | 2012-10-03 | エムジーファーマ株式会社 | Liver disorder improving composition |
JP5465834B2 (en) * | 2008-01-15 | 2014-04-09 | 雪印メグミルク株式会社 | Liver function protectant |
JP5876205B2 (en) * | 2009-02-06 | 2016-03-02 | 松谷化学工業株式会社 | Method for improving deficiency of sweetness of D-sorbose in sweetener comprising D-sorbose and improving sweetness persistence |
JP6157928B2 (en) * | 2012-05-29 | 2017-07-05 | 上野製薬株式会社 | Fat accumulation inhibitor in the liver |
-
2013
- 2013-05-29 JP JP2013113125A patent/JP6437183B2/en active Active
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Torres-Fuentes et al. | A natural solution for obesity: Bioactives for the prevention and treatment of weight gain. A review | |
ES2788166T3 (en) | Compositions and methods using a polyphenol for musculoskeletal health | |
JP2014129323A5 (en) | ||
CN105935364B (en) | Composition comprising ginsenoside F2 for preventing or treating non-alcoholic liver disease | |
JP5752359B2 (en) | Weight gain inhibiting composition and food containing the same | |
EP2992933B1 (en) | Ginsenoside f2 for prophylaxis and treatment of liver disease | |
JP6157928B2 (en) | Fat accumulation inhibitor in the liver | |
KR101559130B1 (en) | Composition comprising herbal extract for preventing or treating obesity | |
Memudu et al. | Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat | |
JP6161438B2 (en) | Fat accumulation inhibitor and / or fat accumulation reducing agent | |
JP2014129324A5 (en) | ||
JP6660668B2 (en) | UCP-1 expression promoter | |
JP5969529B2 (en) | Anti-inflammatory agent | |
WO2016068267A1 (en) | Agent for improving sickness behavior symptoms | |
EP3616705A2 (en) | Composition for improving prevention and treatment of fatty liver containingamomum vilosum | |
JP6553375B2 (en) | UCP-1 expression promoter | |
KR20160058810A (en) | Liver function and/or pancreatic function improving agent | |
KR101591460B1 (en) | Composition comprising mixture extract of Ephedra sinica, Rheum palmatum L and Arnebia euchroma for preventing or treating obesity | |
KR101729236B1 (en) | TLR7 agonist agent for treatment and prevention of liver disease | |
JP6692638B2 (en) | PPARδ activator | |
JP2015003877A (en) | Composition comprising hydroxytyrosol or salt thereof | |
JP2015160841A (en) | Hepatopathy inhibitor induced by ethanol | |
JP6437183B2 (en) | Liver function improving agent | |
KR101644755B1 (en) | Composition for preventing or treating stroke or degenerative brain disease | |
Lee et al. | Effects of an aqueous extract of purple sweet potato on nonalcoholic fatty liver in high fat/cholesterol-fed mice |