JP2014121651A - Ultrasound diagnostic apparatus, ultrasound image analysis apparatus, and ultrasound image analysis program - Google Patents

Abstract

PROBLEM TO BE SOLVED: To accurately display parameter image data in a desired diastolic heartbeat time phase.SOLUTION: A motion parameter measuring unit 9 two-dimensionally measures a motion parameter of a myocardial tissue by a tracking process on time-series ultrasound image data acquired by transmission and reception of ultrasound waves to and from a subject. On the other hand, a time phase setting unit 8 adds a diastolic heartbeat time phase with reference to the systole end, which is set on the basis of a systole end specified by a time phase where a cardiac cavity area of the ultrasound image data is the smallest and a diastole end specified by an R wave in an electrocardiographic waveform of the subject, to each of time-series parameter image data sets generated by a parameter image data generating unit 10 on the basis of the motion parameter. An image data extracting unit 11 then extracts a parameter image data set to which the diastolic heartbeat time phase closest to a desired diastolic heartbeat time phase set by an input unit 13 is added, and displays the extracted parameter image data set on a display unit 12.

Description

  The present invention relates to an ultrasound diagnostic apparatus, an ultrasound image analysis apparatus, and an ultrasound image analysis program, and in particular, a parameter image based on a motion parameter such as a myocardium by analyzing ultrasound image data collected from a subject. The present invention relates to an ultrasonic diagnostic apparatus, an ultrasonic image analysis apparatus, and an ultrasonic image analysis program that enable generation and display of data.

  The ultrasonic diagnostic apparatus radiates an ultrasonic pulse generated from a vibration element built in an ultrasonic probe into a subject, and receives an ultrasonic reflected wave generated by a difference in acoustic impedance of the subject tissue by the vibration element. Displayed on the monitor. This diagnostic method is widely used for morphological diagnosis and functional diagnosis of living organs because real-time two-dimensional image data can be easily observed with a simple operation by simply bringing an ultrasonic probe into contact with the body surface.

  Ultrasound diagnostic methods for obtaining biological information from ultrasound reflected waves from tissues or blood cells in the body have made rapid progress with the development of two major technologies, the ultrasonic pulse reflection method and the ultrasonic Doppler method. Observation of B-mode image data and color Doppler image data obtained by using them is indispensable in today's ultrasonic image diagnosis.

  In recent years, for example, a strain imaging method that enables two-dimensional observation of “distortion” based on movement speed information of myocardial tissue obtained by analyzing ultrasonic image data such as B-mode image data. Has been tried.

  In the strain imaging method for the purpose of diagnosing the function of the heart, for example, B-mode image data is collected in time series on the basis of received signals obtained by ultrasonic scanning on a subject, and then super-adjacent in the time direction is collected. A tracking process by pattern matching is applied to the sonic image data to measure “displacement” in each part of the myocardial tissue. Then, strain image data is generated by calculating a two-dimensional distribution of “distortion” defined as displacement per unit length.

  In addition, a two-dimensional distribution of “strain rate” is obtained from the spatial gradient of the moving speed obtained by TDI (Tissue Doppler Imaging) method, which applies the color Doppler method to display the moving speed of myocardial tissue in two dimensions. A method of generating strain image data by measuring and integrating this “strain rate” with time is also proposed (see, for example, Patent Document 1).

  The time-series strain image data obtained by the strain imaging method described above is superimposed on the ultrasound image data such as the B-mode image data used to generate the strain image data, and is displayed on the monitor of the display unit. It has been displayed as an image.

JP 2005-130877 A

  By the way, in recent ultrasonic diagnosis in the heart region, it has become clear that early diagnosis of heart disease is possible by observing parameter image data such as strain image data in a predetermined time phase in the early stage of diastole in detail. .

  When selectively observing the parameter image data in a predetermined time phase in the early stage of diastole, the “distortion” of the myocardial tissue in the predetermined time phase from the parameter image data continuously displayed as a moving image as in the past. It was difficult to accurately observe the above. In addition, in order to accurately set the predetermined time phase, it is necessary to use the end systole of the myocardial tissue as a reference, and the conventional method based on the end diastole specified by the R wave timing of the electrocardiogram waveform is accurate. It was impossible to set.

  The present invention has been made in view of the above-mentioned problems, and its object is to diagnose when observing parameter image data based on a motion parameter of myocardial tissue obtained by analyzing ultrasonic image data. An object of the present invention is to provide an ultrasonic diagnostic apparatus, an ultrasonic image analysis apparatus, and an ultrasonic image analysis program capable of accurately and reliably displaying parameter image data corresponding to a predetermined heartbeat time phase in an effective diastole.

  In order to achieve the above object, the present invention takes the following measures.

  According to the first aspect of the present invention, a motion parameter of a living tissue is measured based on a plurality of ultrasonic image data collected in time series by ultrasonic scanning on a subject, and parameter image data is based on the motion parameter. An ultrasonic image data storage unit that stores each of the plurality of ultrasonic image data in time series together with information of a heartbeat time phase, and the biological tissue based on the ultrasonic image data. A motion parameter measuring unit for measuring motion parameters, a parameter image data generating unit for generating a plurality of parameter image data in time series based on the motion parameters, and storing each of them together with information on the heartbeat time phase, and the biological tissue The end systole and end diastole from A heart rate period setting unit for setting out, a heart rate time phase setting unit for setting a desired heart rate time phase during diastole based on a predetermined ratio that divides a time interval of diastole of the biological tissue, and the heart rate time phase setting unit And a display unit that extracts and displays the ultrasonic image data and the parameter image data corresponding to the time phase closest to the desired heartbeat time phase set.

  According to a twelfth aspect of the present invention, there is provided an ultrasonic image data storage unit that stores time-series ultrasonic image data collected by ultrasonic scanning on a subject together with information on a heartbeat time phase, and the ultrasonic wave A motion parameter measuring unit for measuring motion parameters of the living tissue based on image data, and a parameter for generating a plurality of parameter image data in time series based on the motion parameters, each of which is stored together with information on the heartbeat time phase An image data generation unit; a heartbeat period setting unit that detects end systole and end diastole from the living tissue; and detects a period from the end systole to end diastole of the living tissue as a diastole; A heartbeat time phase setting unit for setting a desired heartbeat time phase during diastole based on a predetermined ratio for dividing a time interval; A display unit that extracts and displays the ultrasound image data and the parameter image data corresponding to the time phase closest to the desired heartbeat time phase constant unit has set, an ultrasound image analyzer equipped with.

  According to the thirteenth aspect of the present invention, in a computer, time-series ultrasonic image data collected by ultrasonic scanning on a subject and information on a heartbeat time phase associated with each of the ultrasonic image data. Based on the measurement function for measuring the motion parameter of the biological tissue, a parameter image data generation function for generating a plurality of parameter image data in time series based on the motion parameter, and storing each of the parameter image data together with information on the heartbeat time phase A heartbeat period setting function that detects end systole and end diastole from the living tissue, and detects a period from the end systole to the end diastole of the living tissue as a diastole, and a time interval of the diastole of the living tissue A heartbeat time phase setting function for setting a desired heartbeat time phase during the diastole based on a predetermined ratio, and the desired heartbeat time set by the heartbeat time phase setting unit Corresponding to the time phase closest to the an ultrasonic image analysis program, characterized in that to achieve the display function, the which extracts and displays the ultrasound image data and the parameter image data.

  As described above, according to the present invention, when observing the parameter image data based on the motion parameters of the myocardial tissue obtained by analyzing the ultrasound image data, the parameter image corresponding to the predetermined heartbeat time phase in the diastole effective for diagnosis. An ultrasonic diagnostic apparatus, an ultrasonic image analysis apparatus, and an ultrasonic image analysis program that can display data accurately and reliably can be realized.

FIG. 1 is a block diagram showing the overall configuration of the ultrasonic diagnostic apparatus according to the first embodiment of the present invention. FIG. 2 is a block diagram illustrating a specific configuration of the transmission / reception unit and the ultrasonic image data generation unit included in the ultrasonic diagnostic apparatus according to the first embodiment. FIG. 3 shows a desired cardiac time phase in the diastole set by the diastole and systole of the myocardial tissue set by the heart beat period setting unit provided in the ultrasonic diagnostic apparatus of the first embodiment and the heartbeat time phase setting unit. FIG. FIG. 4 is a diagram illustrating a specific example of a heartbeat time phase setting unit provided in the ultrasonic diagnostic apparatus according to the first embodiment. FIG. 5 is a flowchart showing a procedure for generating / displaying parameter image data by the ultrasonic diagnostic apparatus according to the first embodiment. FIG. 6 is a block diagram showing the overall configuration of the ultrasonic image analysis apparatus according to the second embodiment of the present invention. FIG. 7 is a flowchart showing a procedure for generating / displaying parameter image data by the ultrasonic image analysis apparatus according to the second embodiment.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings.

(First embodiment)
The ultrasonic diagnostic apparatus according to the first embodiment of the present invention described below first transmits / receives ultrasonic waves to / from a subject to generate time-series B-mode image data as ultrasonic image data. Tracking processing is performed on the ultrasonic image data, and the “strain” of the myocardial tissue is measured two-dimensionally or three-dimensionally as a motion parameter. On the other hand, the end systole specified by the time phase in which the intracardiac area of the ultrasonic image data is minimized and the R wave in the electrocardiographic waveform of the subject measured in parallel with the acquisition of the ultrasonic image data The diastolic heartbeat time phase based on the end systole is set based on the end diastolic phase, and the diastolic heartbeat time phase is generated based on the motion parameters of the ultrasound image data. Add to each. Then, the parameter image data of the diastolic heartbeat time phase closest to the desired heartbeat time phase of the diastolic set by the input unit is extracted from a plurality of time-series parameter image data and displayed.

  In the following embodiment, a case where “distortion” of myocardial tissue is measured as a motion parameter will be described, but the present invention is not limited to this. For example, “displacement”, “rotation”, “torsion” , “Speed” or the like may be measured as a motion parameter. Further, “strain rate”, “rotation rate”, “twist rate”, “acceleration” and the like indicating these temporal changes may be used.

(Device configuration)
The configuration and basic operation of the ultrasonic diagnostic apparatus according to the first embodiment of the present invention will be described with reference to FIGS. FIG. 1 is a block diagram showing an overall configuration of the ultrasonic diagnostic apparatus, and FIG. 2 is a block diagram showing a specific configuration of a transmission / reception unit and an ultrasonic image data generation unit included in the ultrasonic diagnostic apparatus. is there.

  The ultrasonic diagnostic apparatus 100 shown in FIG. 1 transmits an ultrasonic pulse (transmitted ultrasonic wave) to a diagnosis target part (heart region) of a subject, and an ultrasonic reflected wave (received ultrasonic wave) obtained by this transmission. An ultrasonic probe 3 in which a plurality of vibration elements that convert a signal into an electric signal (reception signal) are arranged, and a drive signal for transmitting an ultrasonic pulse in a predetermined direction of the subject are supplied to the vibration element Then, a transmission / reception unit 2 that performs phasing addition of the reception signals of a plurality of channels obtained from these vibration elements, and an ultrasonic image data generation unit 4 that processes the reception signal after phasing addition and generates ultrasonic image data. And ultrasonic image data to be stored by adding R-wave timing information of an electrocardiographic waveform supplied from an ECG measurement unit 14 to be described later to ultrasonic image data supplied in time series from the ultrasonic image data generation unit 4 Memory A lumen area measuring unit 6 for measuring the intracardiac area in the ultrasonic image data, and ultrasonic image data (first image) that minimizes the intracardiac area from the time-series ultrasonic image data. Ultrasound image data) and ultrasound image data (second ultrasound image data) having R-wave timing information are searched, and the end systole and second ultrasound image data specified by the first ultrasound image data A heart rate period setting unit 7 for setting a diastole and a systole of the myocardial tissue based on the end diastole specified by the diastolic phase, and a heartbeat time phase of the diastole following the end systole with reference to the end systole A time phase setting unit 8 for setting the time phase.

  The ultrasonic diagnostic apparatus 100 includes a motion parameter measuring unit 9 that measures the motion parameters of the myocardial tissue for each of the ultrasonic image data read out from the ultrasonic image data storage unit 5 in time series, and the calculation. The parameter image data is generated based on the two-dimensional motion parameter, and the information of the diastolic heartbeat time phase supplied from the time phase setting unit 8 is added to the parameter image data and stored in its own storage unit. The diastolic heartbeat time phase closest to the desired diastolic heartbeat phase to be described later from the parameter image data generation unit 10 and a plurality of time-series parameter image data stored in the storage unit of the parameter image data generation unit 10 Parameter image data is extracted, and ultrasonic image data corresponding to the parameter image data (that is, used for generating the parameter image data) An image data extraction unit 11 that extracts from a plurality of ultrasonic image data stored in the wave image data storage unit 5; a display unit 12 that combines and displays the extracted ultrasonic image data and parameter image data; Selection of exercise parameters, setting of desired heartbeat time phase in diastole, setting of endocardium and epicardium for reference ultrasonic image data selected from a plurality of ultrasonic image data, and various command signals An ECG measurement unit 14 that measures the electrocardiogram waveform (ECG) of the subject and generates R wave timing information based on the R wave of the obtained electrocardiogram waveform; A system control unit 15 that comprehensively controls each of the above units included in the sonic diagnostic apparatus 100 is provided.

  The ultrasonic probe 3 has N arranged vibration elements (not shown) at its distal end, and transmits and receives ultrasonic waves by bringing the distal end into contact with the body surface of the subject. The vibration element is an electroacoustic transducer that converts electrical pulses (driving signals) into ultrasonic pulses (transmitting ultrasonic waves) during transmission, and converts ultrasonic reflected waves (receiving ultrasonic waves) into electrical reception signals during reception. It has a function to do. Each of these vibration elements is connected to the transmission / reception unit 2 via an N-channel multi-core cable (not shown). In this embodiment, the sector scanning ultrasonic probe 3 having N vibration elements is described. However, an ultrasonic probe corresponding to linear scanning, convex scanning, or the like may be used.

  Next, the transmission / reception unit 2 illustrated in FIG. 2 includes a transmission unit 21 that supplies a drive signal to the vibration element of the ultrasonic probe 3 and a reception unit that performs phasing addition on the reception signal obtained from the vibration element. 22 is provided.

  The transmission unit 21 includes a rate pulse generator 211, a transmission delay circuit 212, and a drive circuit 213. The rate pulse generator 211 transmits transmission ultrasonic waves by dividing the reference signal supplied from the system control unit 15. A rate pulse that determines the repetition period of is generated. The transmission delay circuit 212 includes the same number of independent delay circuits as the Nt number of vibration elements used for transmission, and transmits the transmission ultrasonic wave in a predetermined direction θp and a delay time for converging to a predetermined depth. A deflection delay time for the purpose is applied to the rate pulse supplied from the rate pulse generator 211. The drive circuit 213 has the same number of independent drive circuits as the transmission delay circuit 212, and generates a drive signal based on the rate pulse to which the above-described delay time is given by the transmission delay circuit 212. Then, Nt (Nt ≦ N) vibration elements selected for transmission from among the N vibration elements arrayed by the ultrasonic probe 3 are driven by the drive signal, and transmitted to the body of the subject. It emits sound waves.

  On the other hand, the receiving unit 22 includes Nr channel preamplifiers 221 corresponding to Nr (Nr ≦ N) vibrating elements selected for reception among N vibrating elements built in the ultrasonic probe 3, A / A D converter 222, a reception delay circuit 223, and an adder 224 are provided, and the Nr channel received signal supplied from the receiving vibration element via the preamplifier 221 is converted into a digital signal by the A / D converter 222. And sent to the reception delay circuit 223.

  The reception delay circuit 223 uses an A / D converter to convert a focusing delay time for focusing received ultrasonic waves from a predetermined depth and a deflection delay time for setting reception directivity with respect to a predetermined direction θp. An adder 224 adds the reception signals from the reception delay circuit 223 to each of the reception signals of the Nr channel output from 222. In other words, the reception signal obtained from the predetermined direction θp is phased and added by the reception delay circuit 223 and the adder 224. Note that the reception delay circuit 223 and the adder 224 enable so-called parallel simultaneous reception in which reception directivities in a plurality of directions are simultaneously formed by controlling the delay time. The application of this parallel simultaneous reception method greatly increases the time required for scanning. Shortened to

  Next, the ultrasonic image data generation unit 4 has a function of generating, for example, B-mode image data as ultrasonic image data, and includes an envelope detector 41, a logarithmic converter 42, and an ultrasonic data storage unit 43. ing. The envelope detector 41 envelope-detects the received signal after phasing addition supplied from the adder 224 of the receiving unit 22, and the amplitude of the received signal after the envelope detection is logarithmically converted by the logarithmic converter 42. Thus, B-mode data in the predetermined direction θp is generated. The B mode data sequentially supplied from the logarithmic converter 42 along with ultrasonic transmission / reception in the transmission / reception direction θp (θp = θ1 to θP) is stored in the ultrasonic data storage unit 43 in correspondence with the transmission / reception direction. Sound wave image data (B-mode image data) is generated. Note that the envelope detector 41 and the logarithmic converter 42 may be configured by changing the order.

  Returning to FIG. 1, the ultrasonic image data storage unit 5 is supplied from the ECG measurement unit 14 to, for example, time-series ultrasonic image data for several heartbeat cycles supplied from the ultrasonic image data generation unit 4. R wave timing information of the electrocardiogram waveform is added and saved. That is, R wave timing information is added to the ultrasonic image data (hereinafter referred to as reference ultrasonic image data) generated by the ultrasonic image data generation unit 4 at the time when the R wave of the electrocardiogram waveform is detected. Is done.

  The lumen area measuring unit 6 reads a plurality of time-series ultrasonic image data stored in the ultrasonic image data storage unit 5 and selects the above-described reference ultrasonic image data selected from these ultrasonic image data Tracking processing based on the endocardium set by the input unit 13 for the myocardial tissue is performed on the ultrasound image data for one heartbeat period following the reference ultrasound image data, and intracardiac in these ultrasound image data is obtained. Detect the membrane. Then, the area inside the heart chamber surrounded by the endocardium is measured for each ultrasonic image data, and the measurement result is the identification information (hereinafter referred to as image data identification information) of the ultrasonic image data and the R wave. It is supplied to the heart rate period setting unit 7 together with the timing information.

  Next, the heartbeat period setting unit 7 searches for ultrasound image data (first ultrasound image data) that minimizes the intracardiac area based on the above-described information supplied from the lumen area measurement unit 6. Thus, the end systole is specified, and the end diastole is specified by searching the reference ultrasonic image data (second ultrasonic image data) to which the R-wave timing information is added. Then, the diastole and systole of the myocardial tissue are set based on the above-described end systole and end diastole.

  On the other hand, the time phase setting unit 8 includes a storage circuit (not shown), and for each of the time-series ultrasonic image data collected in the above diastole, a heartbeat time phase based on the end systole (diastolic heartbeat time). Phase). However, this diastolic heartbeat time phase is a ratio based on the period from the end systole to the end diastole (for example, when the period from the end systole to the end diastole is T, 30% of the period T, T / 3, etc. The diastolic heartbeat time phase set at this time is stored in the storage circuit in correspondence with the image data identification information of the ultrasonic image data.

  Next, the motion parameter measurement unit 9 includes a sample point setting unit and a tracking processing unit (not shown). The sample point setting unit reads a plurality of time-series ultrasonic image data stored in the ultrasonic image data storage unit 5, and inputs an input unit for reference ultrasonic image data selected from the ultrasonic image data A plurality of sample points are set at predetermined intervals for the myocardial tissue surrounded by the endocardium and epicardium set by 13. On the other hand, the tracking processing unit performs tracking processing by pattern matching based on the sample points set in the reference ultrasonic image data, and measures, for example, “displacement” in each part of the myocardial tissue. “Strain” defined by displacement per length is measured as a motion parameter.

  The parameter image data generation unit 10 generates a plurality of time-series parameter image data based on the two-dimensional motion parameter measured by the motion parameter measurement unit 9. Next, the diastolic heartbeat time phase stored in the storage circuit of the time phase setting unit 8 is read together with the image data identification information, and the diastolic period corresponding to the image data identification information of the ultrasonic image data used for generating the parameter image data. The heartbeat time phase is added to the above parameter image data and stored in its own storage circuit. That is, the storage circuit of the parameter image data generation 10 stores time-series parameter image data in the diastolic period in which the diastolic heartbeat time phase based on the end systole is set.

  On the other hand, the image data extraction unit 11 extracts ultrasonic image data having R-wave timing information from the time-series ultrasonic image data stored in the ultrasonic image data storage unit 5 as reference ultrasonic image data. To do. Further, based on the information on the desired cardiac time phase in the diastolic phase supplied from the input unit 13 via the system control unit 15, the parameter image to which the information on the diastolic cardiac time phase closest to the desired cardiac time phase is added Data is extracted from a plurality of parameter image data stored in the parameter image data generation unit 10, and the ultrasonic image data used to generate the parameter image data is stored in the ultrasonic image data storage unit 5. Extract from a plurality of ultrasonic image data.

  The display unit 12 includes a display data generation unit 121 and a monitor 122. The display data generation unit 121 performs a predetermined conversion process on the reference ultrasound image data supplied from the image data extraction unit 11 to generate display data. Further, predetermined conversion processing and synthesis processing are performed on the parameter image data and ultrasonic image data of the diastolic heartbeat phase closest to the desired heartbeat time phase of diastolic supplied from the image data extraction unit 11, and necessary Accordingly, display data is generated by adding subject information, an electrocardiogram waveform, and the like. The obtained display data is displayed on the monitor 122.

  The input unit 13 includes an input device such as a keyboard, a trackball, a mouse, a selection button, and an input button and a display panel on the operation panel, and an exercise parameter selection unit 131 for selecting an exercise parameter, a desired heartbeat time phase in diastole And an endocardial setting unit 133 that sets the endocardium and epicardium for the myocardial tissue of the reference ultrasound image data. Also, input of subject information, setting of various image data generation conditions and display conditions, and input of various command signals are performed using the above-described display panel and input device.

  3 shows the diastole and systole of the myocardial tissue set by the heartbeat period setting unit 7 and the desired heartbeat time phase of the diastole set by the heartbeat time phase setting unit 132 described above.

  That is, in FIG. 3A, the systole of the myocardial tissue corresponds to a period Ts from the R wave to the T wave of the electrocardiographic waveform Ec of the subject measured by the ECG measurement unit 14, and the diastole is the electrocardiogram. This corresponds to a period Td from the T wave to the R wave of the shape Ec. As described above, early diagnosis of cardiac disease is performed by measuring the myocardial tissue motion parameters in the desired heartbeat phase Pxo (Pxo = Tx / Tdx100 (%)) in the diastolic phase after a predetermined time Tx from the end systole. Is possible. However, since it is not always easy to detect the T wave from the electrocardiographic waveform Ec of the subject having heart disease and specify the end systole, the intracardiac area indicated in the ultrasonic image data as described above is large. A method of identifying the end systole by detecting the time phase that is minimized is preferable.

  On the other hand, FIG. 3B shows time-series M ultrasound image data in the diastolic period extracted from time-series ultrasound image data generated in parallel with the measurement of the electrocardiogram waveform Ec. Parameter image data E1 to EM generated based on the diastolic heartbeat time phases P1 to PM and the ultrasound image data D1 to DM set by the time phase setting unit 8 with respect to D1 to DM and the ultrasound image data D1 to DM Is schematically shown. That is, in contrast to the ultrasonic image data D1 generated at the end systole indicated by the T wave of the electrocardiogram waveform Ec and the parameter image data E1 obtained by the tracking process based on the ultrasonic image data D1, The phase P1 is set and the ultrasonic image data D2 to DM generated at predetermined intervals following the ultrasonic image data D1 and the parameter image data E2 to EM generated based on these image data are in the expansion period. Heartbeat time phases P2 to PM are set.

  When the desired cardiac time phase Pxo in the diastole is set in the cardiac time phase setting unit 132 of the input unit 13, the image data extraction unit 11 that has received this setting information via the system control unit 15 Parameter image data Ex and ultrasonic image data Dx of the diastolic heartbeat time phase Px corresponding to the phase Pxo (that is, closest to the desired heartbeat time phase Pxo) are extracted and displayed on the display unit 12.

  In the above-described method, the diastolic heartbeat time phases P1 to PM are set for the parameter image data E1 to EM generated in advance, and the parameter image data having the diastolic heartbeat phase Px closest to the desired heartbeat time phase Pxo. Although the case of extracting Ex has been described, the parameter image data Ex may be directly generated based on the ultrasonic image data Dx of the diastolic heartbeat phase Px that is closest to the desired heartbeat phase Pxo.

  Next, a specific example of the heartbeat time phase setting unit 132 provided in the input unit 13 will be described with reference to FIG. The heartbeat time phase setting unit 132 includes a heartbeat time phase display unit 132-a that displays the desired heartbeat time phase Pxo in the diastole by a ratio (%) based on the period from the end systole to the end diastole. A heartbeat time phase update section 132-b that updates the desired heartbeat time phase displayed on the time phase display section 132-a by increasing or decreasing it, and one piece of parameter image data corresponding to the desired heartbeat time phase in the diastole A display mode switching unit 132-c that switches between a fixed display mode for displaying and an update display mode for displaying a plurality of parameter image data corresponding to the desired heartbeat time phase in each of a plurality of heartbeat cycles. Yes. Then, by operating the heartbeat time phase updating unit 132-b while observing the desired heartbeat time phase displayed on the heartbeat time phase display unit 132-a, the desired heartbeat time from the end systole shown in FIG. The period Tx to the phase Pxo is set to a desired ratio (a predetermined ratio between 30% and 34%, for example, about 33% corresponding to 1/3 of the diastole) with respect to the diastole Td. Is done.

  Returning to FIG. 1 again, the ECG measurement unit 14 has a function of generating R wave timing information based on the R wave detected from the electrocardiogram waveform of the subject, and is attached to the surface of the subject body. Measurement electrode for measuring the voltage, an amplification circuit for amplifying the electrocardiogram waveform measured by the measurement electrode to a predetermined amplitude, an A / D converter for converting the amplified electrocardiogram waveform into a digital signal, and digital An R wave detector (not shown) for detecting an R wave by setting a predetermined threshold value for the electrocardiogram waveform converted into a signal is provided.

  The system control unit 15 includes a CPU and a storage circuit (not shown), and various information input / set / selected in the input unit 13 is stored in the storage circuit. The CPU comprehensively controls each unit of the ultrasonic diagnostic apparatus 100 based on the above-described information input from the input unit 13 and information stored in advance in its own storage circuit, Generate and display parameter image data.

(Parameter image data generation / display procedure)
Next, parameter image data generation and display procedures in the present embodiment will be described with reference to the flowchart of FIG.

  Prior to the generation of the parameter image data, the operator of the ultrasonic diagnostic apparatus 100 inputs the subject information with the input unit 13 and then selects “distortion” of the myocardial tissue as the motion parameter with the motion parameter selection unit 131. . Further, the generation conditions of ultrasonic image data and parameter image data, the display conditions of these image data, and the like are initially set, and the measurement electrode provided in the ECG measurement unit 14 is attached to a predetermined part of the subject (FIG. 5). Step S1).

  When the above initial setting is completed, the operator inputs an ultrasonic image data generation start command from the input unit 13 with the tip of the ultrasonic probe 3 fixed to the body surface of the subject. When this command signal is supplied to the system control unit 15, ultrasonic transmission / reception for the purpose of generating time-series ultrasonic image data is started.

  That is, the rate pulse generator 211 in the transmission / reception unit 2 in FIG. 2 divides the reference signal supplied from the system control unit 15 to determine the repetition period of the ultrasonic pulses emitted into the subject. A pulse is generated, and this rate pulse is supplied to the transmission delay circuit 212.

  Next, the transmission delay circuit 212 gives the rate pulse a focusing delay time for focusing the ultrasonic wave to a predetermined depth and a deflection delay time for transmitting the ultrasonic wave in the first transmission / reception direction θ1. A rate pulse is supplied to the drive circuit 213. Then, the drive circuit 213 supplies a drive signal generated based on the rate pulse to Nt transmitting vibration elements in the ultrasonic probe 3 via a cable (not shown), and generates ultrasonic waves in the θ1 direction of the subject. A pulse is emitted.

  A part of the ultrasonic pulse radiated into the subject is reflected at the boundary surface of the heart, myocardial tissue or the like having different acoustic impedance, and these ultrasonic reflected waves (received ultrasonic waves) are Nt in the ultrasonic probe 3. Are converted into Nt-channel electrical signals (reception signals). These received signals are amplified to a predetermined magnitude by the preamplifier 221 of the receiving unit 22, converted into a digital signal by the A / D converter 222, and then a predetermined delay time by the reception delay circuit 223. Are added and synthesized by the adder 224 (phased addition). At this time, the reception delay circuit 223 has a convergence delay time for focusing the ultrasonic reflected wave from a predetermined depth and a deflection delay for giving a strong reception directivity in the transmission / reception direction θ1 with respect to the ultrasonic reflected wave. The time is set based on a control signal from the system control unit 15.

  Next, the envelope detector 41 and the logarithmic converter 42 of the ultrasonic image data generation unit 4 perform envelope detection and logarithmic conversion on the received signal bundled into one channel by the phasing addition in the adder 224 to perform the B mode. Data is generated, and the obtained B-mode data is stored in the ultrasonic data storage unit 43.

  Next, the system control unit 15 performs ultrasonic transmission / reception in the same procedure with respect to the transmission / reception directions θ2 to θP, and the B-mode data obtained at this time is also stored in the ultrasonic data storage unit 43. In other words, the B-mode data obtained by ultrasonic transmission / reception in the transmission / reception directions θ1 to θP is sequentially stored in the ultrasonic data storage unit 43, and B-mode image data for one frame is generated as ultrasonic image data. The obtained ultrasonic image data and image data identification information are stored in the ultrasonic image data storage unit 5.

  Furthermore, by repeating the above-described procedure, for example, ultrasonic image data for several heartbeat cycles is generated in time series, and the ultrasonic image data storage unit also includes image data identification information as supplementary information. 5 are sequentially stored.

  On the other hand, the ECG measurement unit 14 detects an R wave by setting a predetermined threshold value for the electrocardiographic waveform detected by the measurement electrode and A / D converted by the A / D converter. The R wave timing information indicating the timing at which this R wave is detected is sent to the ultrasonic image data storage unit 5, and at this time, supplied from the ultrasonic image data generation unit 4 to the ultrasonic image data storage unit 5. Is added to the ultrasonic image data. That is, the B-mode image data generated in the R wave heartbeat time phase is stored in the ultrasonic image data storage unit 5 with the R wave timing information and the image data identification information as supplementary information (step S2 in FIG. 5).

  When the generation and storage of time-series ultrasonic image data (B-mode image data) for the subject is completed, the image data extraction unit 11 stores the time-series ultrasonic data stored in the ultrasonic image data storage unit 5. Ultrasonic image data having R-wave timing information is extracted from the ultrasonic image data as reference ultrasonic image data and displayed on the monitor 122 of the display unit 12. The operator who has observed the reference ultrasound image data displayed on the display unit 12 uses the endocardium setting unit 133 of the input unit 13 to perform endocardium and epicardium on the myocardial tissue of the reference ultrasound image data. Is set (step S3 in FIG. 5).

  Next, the lumen area measuring unit 6 reads out a plurality of time-series ultrasonic image data stored in the ultrasonic image data storage unit 5 and selects the above-described reference ultrasonic wave selected from these ultrasonic image data. Tracking processing based on the endocardium set by the input unit 13 for the myocardial tissue in the ultrasound image data is performed on the ultrasound image data for one heartbeat period following the reference ultrasound image data, and these ultrasound images are obtained. Detect endocardium in the data. Then, the intracardiac area surrounded by the endocardium is measured for each ultrasonic image data, and the measurement result is supplied to the heartbeat period setting unit 7 together with the image data identification information and the R wave timing information (FIG. 5). Step S4).

  On the other hand, the heartbeat period setting unit 7 searches for ultrasound image data (first ultrasound image data) that minimizes the intracardiac area based on the above-described information supplied from the lumen area measurement unit 6. The end systole is specified by, and the end diastole is specified by searching ultrasonic image data (second ultrasonic image data) having R-wave timing information. Then, the diastole and systole of the myocardial tissue are set based on the above-mentioned end systole and end diastole (step S5 in FIG. 5).

  Then, the time phase setting unit 8 sets a diastolic heartbeat time phase based on the end systole for each of the time-series ultrasonic image data collected in the diastole, and the set diastolic heartbeat time phase is set. Is stored in its own storage circuit in correspondence with the image data identification information of the ultrasonic image data (step S6 in FIG. 5).

  Next, the sample point setting unit of the motion parameter measurement unit 9 reads out a plurality of time-series ultrasonic image data stored in the ultrasonic image data storage unit 5 and selects from these ultrasonic image data. A plurality of sample points are set at predetermined intervals for the myocardial tissue surrounded by the endocardium and epicardium set by the input unit 13 for the reference ultrasound image data. On the other hand, the tracking processing unit of the motion parameter measuring unit 9 performs tracking processing by pattern matching based on the sample points set in the reference ultrasonic image data, and measures “displacement” in each part of the myocardial tissue, Further, “strain” defined by the displacement per unit length is measured as a motion parameter (step S7 in FIG. 5).

  Next, the parameter image data generation unit 10 generates a plurality of time-series parameter image data based on the motion parameters measured two-dimensionally by the motion parameter measurement unit 9 (step S8 in FIG. 5). Next, for example, a 33% heartbeat time phase (a heartbeat time phase that is about 1/3 of the diastole) is set by the heartbeat time phase setting unit 132 of the input unit 13 as a desired heartbeat time phase of the diastole, The diastolic heartbeat time phase stored in the storage circuit of the phase setting unit 8 is read together with the image data identification information, and the diastolic heartbeat phase corresponding to the image data identification information of the ultrasonic image data used to generate the parameter image data Is set in the parameter image data described above. Then, the parameter image data to which the set information of the diastolic heartbeat time phase is added is stored in its own storage circuit (step S9 in FIG. 5).

  When the storage of the parameter image data set with the diastolic heartbeat time phase is completed, the image data extraction unit 11 supplies the diastolic phase supplied from the heartbeat time phase setting unit 132 of the input unit 13 via the system control unit 15. A plurality of parameter image data stored in the parameter image data generation unit 10 based on the desired heartbeat time phase information, to which parameter image data to which information on the diastolic heartbeat time phase closest to the desired heartbeat time phase has been added. Further, ultrasonic image data corresponding to the parameter image data is extracted from a plurality of ultrasonic image data stored in the ultrasonic image data storage unit 5.

  Then, the display data generation unit 121 of the display unit 12 performs a predetermined conversion process on the parameter image data and ultrasonic image data of the diastolic heartbeat time phase closest to the desired heartbeat time phase supplied from the image data extraction unit 11. And display data by adding subject information, an electrocardiogram waveform and the like as necessary. The obtained display data is displayed on the monitor 122 (step S10 in FIG. 5). In the display, parameter values may be averaged and displayed for each segment recommended by ASE (American Society of Echocardiography), AHA (American Heart Association), or the like.

  According to the first embodiment of the present invention described above, when observing the parameter image data based on the motion parameters of the myocardial tissue obtained by analyzing the ultrasound image data, the desired expansion period effective for diagnosis is desired. The parameter image data of the diastolic heartbeat time phase closest to the heartbeat time phase can be accurately and reliably displayed. For this reason, diagnostic efficiency and diagnostic accuracy are improved, and the burden on the operator is reduced.

  In particular, in this embodiment, since the end systole of the myocardial tissue is specified based on the ultrasound image data that minimizes the intracardiac area selected from the time-series ultrasound image data, this end systole It is possible to accurately set the desired heartbeat time phase in the diastole with reference to whether or not the T wave can be detected in the electrocardiographic waveform.

  Furthermore, since the desired heartbeat time phase in the diastole is set by the% heartbeat time phase based on the diastole, it is easy to set a heartbeat time phase that is effective for diagnosis even when there are individual differences in the heartbeat cycle. It becomes possible.

(Second Embodiment)
Next, a second embodiment of the present invention will be described. The ultrasonic image analysis apparatus according to the second embodiment first tracks time-series ultrasonic image data collected in advance with R wave timing information based on an electrocardiographic waveform of a subject added. Processing is performed to measure the motion parameters of the myocardial tissue two-dimensionally. On the other hand, the end systole is determined based on the end systole specified by the time phase in which the intracardiac area of the ultrasound image data is minimized and the end diastole specified by the R wave timing information added to the ultrasound image data. The diastolic heartbeat time phase is set, and the diastolic heartbeat time phase is added to each of the time-series parameter image data generated based on the motion parameters of the ultrasonic image data. Then, the parameter image data of the diastolic heartbeat time phase closest to the desired heartbeat time phase of the diastolic set by the input unit is extracted from a plurality of time-series parameter image data and displayed.

(Device configuration)
The configuration of the ultrasonic image analysis apparatus according to the second embodiment of the present invention will be described with reference to FIG. FIG. 6 is a block diagram showing the overall configuration of the ultrasonic image analyzing apparatus in the present embodiment, and the same configuration and function as the unit of the ultrasonic diagnostic apparatus 100 in the first embodiment shown in FIG. The same units are given the same reference numerals, and detailed description thereof is omitted.

  That is, the ultrasonic image analysis apparatus 200 shown in FIG. 6 includes a plurality of time-series ultrasonic image data supplied from a separately installed ultrasonic diagnostic apparatus via a network or a storage medium, and these ultrasonic image data. An ultrasonic image data storage unit 16 that stores R-wave timing information of an electrocardiographic waveform added to the sensor, a lumen area measurement unit 6 that measures the intracardiac area in these ultrasonic image data, and time series Ultrasound image data (first ultrasound image data) that minimizes the inner area of the heart chamber from among the ultrasound image data, and ultrasound image data (second ultrasound image data) having R-wave timing information. The heartbeat period which searches and sets the diastole and the systole of the myocardial tissue based on the end systole specified by the first ultrasonic image data and the end diastole specified by the second ultrasonic image data A setting unit 7, the end systole as a reference and a phase setting section 8 when setting subsequent diastolic cardiac time phase (diastolic heartbeat time phase) in the end systole.

  The ultrasonic image analyzing apparatus 200 includes a motion parameter measuring unit 9 that measures the motion parameters of the myocardial tissue for each of the ultrasonic image data read out in time series from the ultrasonic image data storage unit 16; Based on the calculated two-dimensional motion parameters, parameter image data is generated, and information on the diastolic heartbeat time phase supplied from the time phase setting unit 8 is added to the parameter image data and stored in its own storage unit. The parameter image data generation unit 10 that performs the diastolic heartbeat time phase closest to the desired heartbeat time phase of the diastolic phase from among a plurality of time-series parameter image data stored in the storage unit of the parameter image data generation unit 10 The parameter image data is extracted, and the ultrasonic image data corresponding to the parameter image data is further stored in the ultrasonic image data storage unit 5. Image data extraction unit 11 that extracts from image data, display unit 12 that combines and displays the extracted ultrasonic image data and parameter image data, selection of exercise parameters, setting of desired heartbeat time phase in diastole An input unit 13 for setting endocardium and epicardium with respect to reference ultrasonic image data selected from a plurality of ultrasonic image data, and inputting various command signals, and an ultrasonic image analyzing apparatus 200 includes a system control unit 15a that comprehensively controls the above-described units included in 200.

(Parameter image data generation / display procedure)
Next, parameter image data generation and display procedures in the present embodiment will be described with reference to the flowchart of FIG. However, in FIG. 7, the same steps as the parameter image data generation / display procedure in the first embodiment shown in FIG. 5 are denoted by the same reference numerals, and detailed description thereof is omitted.

  Prior to the generation of parameter image data, a plurality of time-series ultrasonic image data collected by a separately installed ultrasonic diagnostic apparatus and R-wave timing information based on an electrocardiographic waveform added to these image data are networked. Alternatively, it is stored in the ultrasonic image data storage unit 16 of the ultrasonic image analysis apparatus 200 via a storage medium (step S21 in FIG. 7).

  Then, the operator of the ultrasonic image analysis apparatus 200 inputs subject information with the input unit 13, then selects a motion parameter suitable for diagnosis with the motion parameter selection unit 131, and further generates parameter image data. Initial setting of conditions, display conditions of ultrasonic image data and parameter image data, etc. is performed (step S22 in FIG. 7).

  When the above initial setting is completed, the operator inputs a parameter image data generation start command from the input unit 13. Then, when this command signal is supplied to the system control unit 15a, generation of time-series parameter image data is started.

  That is, the image data extraction unit 11 uses, as reference ultrasonic image data, ultrasonic image data having R-wave timing information from time-series ultrasonic image data stored in the ultrasonic image data storage unit 16. Extracted and displayed on the monitor 122 of the display unit 12. The operator who has observed the reference ultrasound image data displayed on the display unit 12 uses the endocardium setting unit 133 of the input unit 13 to perform endocardium and epicardium on the myocardial tissue of the reference ultrasound image data. Is set (step S23 in FIG. 7).

  Next, the diastolic heartbeat time phase is set for the ultrasound image data by the procedure of steps S4 to S6 in FIG. 7, and the time-series parameters based on the ultrasound image data by the procedure of steps S7 to S8 of FIG. Image data is generated. In step S9 in FIG. 7, the diastolic heartbeat time phase of the ultrasound image data used for generating the parameter image data is set for the parameter image data. In step S10 in FIG. The parameter image data and ultrasonic image data of the diastolic heartbeat time phase closest to the desired heartbeat time phase of the diastolic phase extracted from the plurality of time-series parameter image data and ultrasonic image data and displayed on the display unit 12 Displayed on the monitor 122.

  According to the second embodiment of the present invention described above, it is effective for diagnosis when observing parameter image data based on a motion parameter of myocardial tissue obtained by analyzing ultrasonic image data collected in advance. The parameter image data of the diastolic heartbeat time phase closest to the desired heartbeat time phase of the diastolic phase can be accurately and reliably displayed. For this reason, diagnostic efficiency and diagnostic accuracy are improved, and the burden on the operator is reduced.

  In particular, in the present embodiment, as in the first embodiment, the end systole of the myocardial tissue based on the ultrasound image data that minimizes the intracardiac area selected from the time-series ultrasound image data. Therefore, it is possible to accurately set a desired heartbeat time phase of the diastole based on the end systole without using a T wave having an electrocardiographic waveform that is difficult to detect. Since the desired heartbeat time phase is set by the% heartbeat time phase based on the diastolic phase, it is possible to easily set a heartbeat time phase effective for diagnosis even when there are individual differences in the heartbeat cycle.

  Furthermore, according to the second embodiment described above, parameter image data is generated and displayed based on time-series ultrasonic image data supplied from a separately installed ultrasonic diagnostic apparatus via a network or the like. Therefore, the operator can efficiently diagnose the subject without much restrictions on time and place.

  As mentioned above, although embodiment of this invention was described, this invention is not limited to the above-mentioned embodiment, It can change and implement. For example, in the above-described embodiment, a time series in which the diastolic heartbeat time phase is set using time-series ultrasonic image data stored in advance in the ultrasonic image data storage unit 5 or the ultrasonic image data storage unit 16. A case in which static parameter image data is generated, and one piece of parameter image data in the diastolic heartbeat time phase Px closest to the desired diastolic heartbeat phase Pxo is selected from these parameter image data and displayed statically. As described above, the parameter image data of the diastolic heartbeat time phase Px may be selected over a plurality of heartbeat cycles, and these parameter image data may be displayed continuously. The display mode switching unit 132- shown in FIG. You may display, updating sequentially using c.

  Further, the systolic period Ts and the period Ts from the end systole to the desired heartbeat phase Px are set in advance by the heartbeat period setting unit 7 and the heartbeat time phase setting unit 132, and then from the generation timing of the R wave in the electrocardiogram waveform. The parameter image data of the diastolic heartbeat time phase Px based on the ultrasound image data supplied from the ultrasound image data generation unit 4 or the separately installed ultrasound diagnostic device at the time when the predetermined time T0 (T0≈Ts + Tx) has elapsed. May be generated. According to this method, parameter image data in the diastolic heartbeat time phase Px can be displayed in real time in units of heartbeat cycles. For example, the temporal change of the myocardial tissue in the subject before and after exercise load or drug load can be accurately determined. Can be observed.

  In the above-described embodiment, the case where “distortion” of myocardial tissue is measured as a motion parameter has been described. However, “displacement”, “rotation”, “torsion”, “speed”, and the like are measured as motion parameters. Alternatively, it may be “distortion rate”, “rotation rate”, “twist rate”, “acceleration” or the like indicating these temporal changes.

  Furthermore, although the case where the ultrasonic image data obtained at the timing when the R wave of the electrocardiogram waveform is generated is set as the reference ultrasonic image data used for the initial setting of the endocardium and the epicardium has been described, The ultrasonic image data obtained in the heartbeat time phase may be set as the reference ultrasonic image data.

  On the other hand, the ultrasonic image data generated by the ultrasonic image data generation unit 4 is not limited to B-mode image data, but is other ultrasonic image data such as color Doppler image data or TDI image data. These ultrasonic image data may be generated three-dimensionally.

  In the above-described embodiment, the case where the desired heartbeat time phase Pxo is set at the time point when the time-series parameter image data is generated by the parameter image data generation unit 10 (step S9 in FIG. 5 or FIG. 7) has been described. However, the desired heartbeat time phase Pxo may be set in the initial setting in step S1.

  On the other hand, in the above-described embodiment, the case where the parameter image data and the ultrasonic image data are combined and displayed has been described. However, the display may be parallel display or display of only the parameter image data. A plurality of parameter image data of desired heartbeat phase Px generated in different states such as before and after loading may be displayed in parallel.

  Furthermore, although the case where the end systole of the myocardial tissue is specified by the ultrasound image data that minimizes the area in the heart chamber has been described, the end systole is specified by the closing timing of the aortic valve observed in the ultrasound image data. It may be performed based on the T wave generation timing when it is easy to observe the T wave in the electrocardiographic waveform.

  In the above-described embodiment, the case has been described in which ultrasonic data obtained by logarithmic conversion by the logarithmic converter 42 of the ultrasonic image data generation unit 4 is subjected to tracking processing to measure various motion parameters. However, the received signal output from the adder 224 of the receiving unit 22 or the output signal of the envelope detector 41 may be tracked.

  Further, diastolic heartbeat time phases P1 to PM are set for the parameter image data E1 to EM generated by the parameter image data generation unit 10, and the parameter having the diastolic heartbeat time phase Px closest to the desired heartbeat time phase Pxo. Although the case where the image data Ex is extracted has been described, the parameter image data Ex may be directly generated based on the ultrasound image data Dx of the diastolic heartbeat phase Px that is closest to the desired heartbeat phase Pxo.

  Each unit of the lumen area measuring unit 6, the heartbeat period setting unit 7, the time phase setting unit 8, the motion parameter measuring unit 9, the parameter image data generating unit 10, and the image data extracting unit 11 shown in FIG. 1 or FIG. Measurement of intracardiac area, setting of myocardial tissue diastole and systole, setting of diastolic heartbeat time phase, measurement of myocardial tissue motion parameters, generation of parameter image data and desired heartbeat time phase Extraction of parameter image data in the diastolic heartbeat time phase can be performed by hardware, but all or a part of these is usually performed by software.

DESCRIPTION OF SYMBOLS 2 ... Transmission / reception part 21 ... Transmission part 22 ... Reception part 3 ... Ultrasonic probe 4 ... Ultrasound image data generation part 5 ... Ultrasound image data storage part 6 ... Lumen area measurement part 7 ... Heart rate period setting part 8 ... Time phase Setting unit 9: Exercise parameter measurement unit 10 ... Parameter image data generation unit 11 ... Image data extraction unit 12 ... Display unit 121 ... Display data generation unit 122 ... Monitor 13 ... Input unit 131 ... Exercise parameter selection unit 132 ... Heartbeat time phase setting Unit 133 ... Inner / Outer membrane setting unit 14 ... ECG measurement unit 15, 15a ... System control unit 16 ... Ultrasonic image data storage unit 100 ... Ultrasonic diagnostic apparatus 200 ... Ultrasonic image analysis apparatus

Claims (13)

In an ultrasonic diagnostic apparatus for measuring a motion parameter of a biological tissue based on a plurality of ultrasonic image data collected in time series by ultrasonic scanning on a subject and generating parameter image data based on the motion parameter,
An ultrasound image data storage unit for storing each of the plurality of ultrasound image data in time series together with information on a heartbeat time phase;
A motion parameter measurement unit for measuring motion parameters of the living tissue based on the ultrasound image data;
A parameter image data generating unit that generates a plurality of parameter image data in a time series based on the motion parameters, and stores each of the parameter image data together with information on the heartbeat time phase;
A heartbeat period setting unit that detects end systole and end diastole from the living tissue, and detects a period from the end systole to end diastole of the living tissue as a diastole;
A heartbeat time phase setting unit that sets a desired heartbeat time phase during the diastole based on a predetermined ratio that divides the time interval of the diastole of the biological tissue;
A display unit that extracts and displays the ultrasound image data and the parameter image data corresponding to the time phase closest to the desired heartbeat time phase set by the heartbeat time phase setting unit;
An ultrasonic diagnostic apparatus comprising: The motion parameter measuring unit is
Set a plurality of sample points for the biological tissue in the ultrasonic image data,
The ultrasonic diagnostic apparatus according to claim 1, wherein a motion parameter of the living tissue is measured by a tracking process using pattern matching with the sample point as a reference.   3. The super-parameter according to claim 1, wherein the motion parameter measurement unit measures at least one of strain, displacement, rotation, twist, speed, strain rate, rotation rate, twist rate, and acceleration of the biological tissue as the motion parameter. Ultrasonic diagnostic equipment. A lumen area measuring unit for measuring the lumen area of the living tissue in the ultrasonic image data, and an ECG measuring unit for measuring an electrocardiographic waveform of the subject,
The heartbeat period setting unit includes the electrocardiographic waveform measured by the ECG measurement unit and the end systole identified by the ultrasound image data that minimizes the lumen area of the living tissue measured by the lumen area measurement unit. The ultrasonic diagnostic apparatus according to claim 1, wherein the diastolic phase and the systolic phase of the living tissue are detected based on the end diastole specified by the R-wave timing information. An ECG measurement unit for measuring an electrocardiographic waveform of the subject;
The heart rate period setting unit detects a diastole and a systole of the living tissue based on R wave timing information and T wave timing information of the electrocardiographic waveform measured by the ECG measurement unit. The ultrasonic diagnostic apparatus as described in any one of them. A timing designating unit for designating the closing timing of the ultrasound image data in the aortic valve and an ECG measuring unit for measuring the electrocardiographic waveform of the subject;
The heart rate period setting unit is based on the end systole specified by the closing timing information by the timing specifying unit and the end diastole specified by the R wave timing information of the electrocardiogram waveform measured by the ECG measurement unit. The ultrasonic diagnostic apparatus according to claim 1, which detects a diastole and a systole.   The heartbeat time phase setting unit sets the diastolic heartbeat time phase indicated by a ratio based on a period from the end systole to the end diastole following the end systole. The ultrasonic diagnostic apparatus according to one item.   The ultrasonic diagnostic apparatus according to claim 1, wherein the display unit displays a plurality of desired heartbeat time phase parameter image data generated under different imaging conditions in parallel.   The heartbeat time phase setting unit sets a time point from the end systole to T / 3 as the diastole heartbeat time phase with reference to a period T from the end systole to the end diastole following the end systole. The ultrasonic diagnostic apparatus as described in any one of thru | or 8.   The heartbeat time phase setting unit sets a time point from 0.30T to 0.34T from the end systole as the diastolic heartbeat time phase with reference to a period T from the end systole to the end diastole following the end systole. The ultrasonic diagnostic apparatus according to any one of claims 1 to 8. The display unit is
Segment the biological tissue according to predetermined criteria;
The ultrasonic diagnostic apparatus according to claim 1, wherein the motion parameter values are averaged for each segment obtained by the segmentation and displayed as the parameter image data. An ultrasonic image data storage unit for storing time-series ultrasonic image data collected by ultrasonic scanning on a subject together with information on a heartbeat time phase;
A motion parameter measurement unit for measuring motion parameters of the living tissue based on the ultrasound image data;
A parameter image data generating unit that generates a plurality of parameter image data in a time series based on the motion parameters, and stores each of the parameter image data together with information on the heartbeat time phase;
A heartbeat period setting unit that detects end systole and end diastole from the living tissue, and detects a period from the end systole to end diastole of the living tissue as a diastole;
A heartbeat time phase setting unit that sets a desired heartbeat time phase during the diastole based on a predetermined ratio that divides the time interval of the diastole of the biological tissue;
A display unit that extracts and displays the ultrasound image data and the parameter image data corresponding to the time phase closest to the desired heartbeat time phase set by the heartbeat time phase setting unit;
An ultrasonic image analysis apparatus. On the computer,
Based on time-series ultrasound image data collected by ultrasound scanning on the subject and information on heartbeat time phases associated with each of the ultrasound image data, the motion parameter of the living tissue is measured. Measurement function,
A parameter image data generation function for generating a plurality of parameter image data in a time series based on the exercise parameters, and storing each of the parameter image data together with information on the heartbeat time phase;
Detecting the end systole and end diastole from the living tissue, and detecting a period from the end systole to the end diastole of the living tissue as a diastole;
A heartbeat time phase setting function for setting a desired heartbeat time phase during the diastole based on a predetermined ratio that divides the time period of the diastole of the biological tissue;
A display function for extracting and displaying the ultrasound image data and the parameter image data corresponding to the time phase closest to the desired heartbeat time phase set by the heartbeat time phase setting unit;
An ultrasonic image analysis program characterized by realizing the above.

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