JP2013544091A5 - - Google Patents
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- Publication number
- JP2013544091A5 JP2013544091A5 JP2013537878A JP2013537878A JP2013544091A5 JP 2013544091 A5 JP2013544091 A5 JP 2013544091A5 JP 2013537878 A JP2013537878 A JP 2013537878A JP 2013537878 A JP2013537878 A JP 2013537878A JP 2013544091 A5 JP2013544091 A5 JP 2013544091A5
- Authority
- JP
- Japan
- Prior art keywords
- opsin
- compound
- photoresponsive
- measurement
- light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 16
- 208000028017 Psychotic disease Diseases 0.000 claims 11
- 150000001875 compounds Chemical class 0.000 claims 10
- 238000005259 measurement Methods 0.000 claims 6
- 210000000170 cell membrane Anatomy 0.000 claims 4
- 230000036755 cellular response Effects 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 3
- 230000028161 membrane depolarization Effects 0.000 claims 3
- 230000002186 photoactivation Effects 0.000 claims 3
- 210000001176 projection neuron Anatomy 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 210000002442 prefrontal cortex Anatomy 0.000 claims 2
- 230000001960 triggered effect Effects 0.000 claims 2
- 101150052863 THY1 gene Proteins 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 230000006399 behavior Effects 0.000 claims 1
- 230000003542 behavioural effect Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 210000005257 cortical tissue Anatomy 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000021824 exploration behavior Effects 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 230000010287 polarization Effects 0.000 claims 1
- 230000002360 prefrontal effect Effects 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41072010P | 2010-11-05 | 2010-11-05 | |
| US41072510P | 2010-11-05 | 2010-11-05 | |
| US61/410,720 | 2010-11-05 | ||
| US61/410,725 | 2010-11-05 | ||
| PCT/US2011/059383 WO2012061741A2 (en) | 2010-11-05 | 2011-11-04 | Control and characterization of psychotic states |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016155068A Division JP2017029148A (ja) | 2010-11-05 | 2016-08-05 | 精神病状態の制御および特徴付け |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544091A JP2013544091A (ja) | 2013-12-12 |
| JP2013544091A5 true JP2013544091A5 (enExample) | 2014-12-18 |
| JP5986575B2 JP5986575B2 (ja) | 2016-09-06 |
Family
ID=46025139
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537878A Expired - Fee Related JP5986575B2 (ja) | 2010-11-05 | 2011-11-04 | 精神病状態の制御および特徴付け |
| JP2016155068A Pending JP2017029148A (ja) | 2010-11-05 | 2016-08-05 | 精神病状態の制御および特徴付け |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016155068A Pending JP2017029148A (ja) | 2010-11-05 | 2016-08-05 | 精神病状態の制御および特徴付け |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20140082758A1 (enExample) |
| EP (1) | EP2635110B1 (enExample) |
| JP (2) | JP5986575B2 (enExample) |
| CN (2) | CN106267236A (enExample) |
| AU (3) | AU2011323197B2 (enExample) |
| CA (1) | CA2816987C (enExample) |
| ES (1) | ES2682962T3 (enExample) |
| WO (1) | WO2012061741A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8926959B2 (en) | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US10052497B2 (en) | 2005-07-22 | 2018-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US9238150B2 (en) | 2005-07-22 | 2016-01-19 | The Board Of Trustees Of The Leland Stanford Junior University | Optical tissue interface method and apparatus for stimulating cells |
| US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
| US20070053996A1 (en) | 2005-07-22 | 2007-03-08 | Boyden Edward S | Light-activated cation channel and uses thereof |
| WO2008086470A1 (en) | 2007-01-10 | 2008-07-17 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| WO2008101128A1 (en) | 2007-02-14 | 2008-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System, method and applications involving identification of biological circuits such as neurological characteristics |
| WO2008106694A2 (en) | 2007-03-01 | 2008-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Systems, methods and compositions for optical stimulation of target cells |
| US10035027B2 (en) | 2007-10-31 | 2018-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Device and method for ultrasonic neuromodulation via stereotactic frame based technique |
| US10434327B2 (en) | 2007-10-31 | 2019-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Implantable optical stimulators |
| SG189813A1 (en) | 2008-04-23 | 2013-05-31 | Univ Leland Stanford Junior | Systems, methods and compositions for optical stimulation of target cells |
| JP5890176B2 (ja) | 2008-05-29 | 2016-03-22 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | セカンドメッセンジャーを光制御するためのセルライン、システム、および方法 |
| EP2303405A4 (en) | 2008-06-17 | 2017-12-27 | The Board of Trustees of the Leland Stanford Junior University | Apparatus and methods for controlling cellular development |
| AU2009260029B2 (en) | 2008-06-17 | 2016-03-17 | The Board Of Trustees Of The Leland Stanford Junior University | Methods, systems and devices for optical stimulation of target cells using an optical transmission element |
| US9101759B2 (en) | 2008-07-08 | 2015-08-11 | The Board Of Trustees Of The Leland Stanford Junior University | Materials and approaches for optical stimulation of the peripheral nervous system |
| NZ602416A (en) | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
| JP5866332B2 (ja) | 2010-03-17 | 2016-02-17 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 感光性イオンを通過させる分子 |
| WO2012061681A1 (en) | 2010-11-05 | 2012-05-10 | The Board Of Trustees Of The Leland Stanford Junior University. | Control and characterization of memory function |
| EP3486253A1 (en) | 2010-11-05 | 2019-05-22 | The Board of Trustees of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| CA2816987C (en) * | 2010-11-05 | 2018-09-18 | The Board Of Trustees Of The Leland Stanford Junior University | Control and characterization of psychotic states |
| US9992981B2 (en) | 2010-11-05 | 2018-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of reward-related behaviors |
| CN106106368A (zh) | 2010-11-05 | 2016-11-16 | 斯坦福大学托管董事会 | 光控cns功能障碍 |
| CA2817175C (en) | 2010-11-05 | 2019-09-24 | The Board Of Trustees Of The Leland Stanford Junior University | Upconversion of light using lanthanide-doped nanoparticles for use in optogenetic methods |
| CN103491770B (zh) | 2010-11-05 | 2016-06-08 | 斯坦福大学托管董事会 | 稳定阶跃函数视蛋白及其使用方法 |
| US8696722B2 (en) | 2010-11-22 | 2014-04-15 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic magnetic resonance imaging |
| EP3524676A1 (en) | 2011-12-16 | 2019-08-14 | The Board of Trustees of The Leland Stanford Junior University | Opsin polypeptides and methods of use thereof |
| ES2628006T3 (es) | 2012-02-21 | 2017-08-01 | Circuit Therapeutics, Inc. | Composiciones para el tratamiento de trastornos neurogénicos del suelo pélvico |
| US10974064B2 (en) | 2013-03-15 | 2021-04-13 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of behavioral state |
| US9636380B2 (en) | 2013-03-15 | 2017-05-02 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of inputs to the ventral tegmental area |
| WO2014179331A2 (en) | 2013-04-29 | 2014-11-06 | The Board Of Trustees Of The Leland Stanford Junior University | Devices, systems and methods for optogenetic modulation of action potentials in target cells |
| CA2921221A1 (en) | 2013-08-14 | 2015-02-19 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for controlling pain |
| EP3122761B1 (en) | 2014-03-28 | 2019-03-06 | The Board of Trustees of The Leland Stanford Junior University | Engineered light-activated anion channel proteins and methods of use thereof |
| US9279797B2 (en) | 2014-06-12 | 2016-03-08 | Axion Biosystems, Inc. | Multiwell microelectrode array with optical stimulation |
| WO2016209654A1 (en) | 2015-06-22 | 2016-12-29 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and devices for imaging and/or optogenetic control of light-responsive neurons |
| US11294165B2 (en) | 2017-03-30 | 2022-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Modular, electro-optical device for increasing the imaging field of view using time-sequential capture |
| WO2025041032A1 (en) * | 2023-08-22 | 2025-02-27 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in layer 5 cells in mouse cortex |
| WO2025041033A1 (en) * | 2023-08-22 | 2025-02-27 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in layer 5 pyramidal tract cells in mouse cortex |
| WO2025041034A1 (en) * | 2023-08-22 | 2025-02-27 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in layer 5 cells in mouse cortex |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001263199B2 (en) * | 2000-05-17 | 2004-09-16 | Asterias Biotherapeutics, Inc. | Neural progenitor cell populations |
| EP1573314B1 (en) * | 2002-12-16 | 2008-07-23 | Genentech, Inc. | Transgenic mice expressing human cd20 |
| US9238150B2 (en) | 2005-07-22 | 2016-01-19 | The Board Of Trustees Of The Leland Stanford Junior University | Optical tissue interface method and apparatus for stimulating cells |
| US7521590B2 (en) * | 2006-09-01 | 2009-04-21 | Korea Institute Of Science And Technology | Phospholipase C β1 (PLCβ1) knockout mice as a model system for testing schizophrenia drugs |
| NZ602416A (en) * | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
| WO2011005978A2 (en) * | 2009-07-08 | 2011-01-13 | Duke University | Methods of manipulating cell signaling |
| EP3486253A1 (en) * | 2010-11-05 | 2019-05-22 | The Board of Trustees of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| CN103491770B (zh) | 2010-11-05 | 2016-06-08 | 斯坦福大学托管董事会 | 稳定阶跃函数视蛋白及其使用方法 |
| CA2816987C (en) * | 2010-11-05 | 2018-09-18 | The Board Of Trustees Of The Leland Stanford Junior University | Control and characterization of psychotic states |
-
2011
- 2011-11-04 CA CA2816987A patent/CA2816987C/en not_active Expired - Fee Related
- 2011-11-04 ES ES11838895.8T patent/ES2682962T3/es active Active
- 2011-11-04 US US13/882,566 patent/US20140082758A1/en not_active Abandoned
- 2011-11-04 CN CN201610649118.6A patent/CN106267236A/zh active Pending
- 2011-11-04 EP EP11838895.8A patent/EP2635110B1/en not_active Not-in-force
- 2011-11-04 JP JP2013537878A patent/JP5986575B2/ja not_active Expired - Fee Related
- 2011-11-04 AU AU2011323197A patent/AU2011323197B2/en not_active Ceased
- 2011-11-04 WO PCT/US2011/059383 patent/WO2012061741A2/en not_active Ceased
- 2011-11-04 CN CN201180060052.2A patent/CN103339505B/zh not_active Expired - Fee Related
-
2016
- 2016-02-15 AU AU2016200948A patent/AU2016200948A1/en not_active Abandoned
- 2016-07-19 US US15/214,402 patent/US20160316732A1/en not_active Abandoned
- 2016-08-05 JP JP2016155068A patent/JP2017029148A/ja active Pending
-
2018
- 2018-07-24 AU AU2018208657A patent/AU2018208657A1/en not_active Abandoned
-
2020
- 2020-08-25 US US17/002,330 patent/US20210059230A1/en not_active Abandoned
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