JP2013538566A - 改良された抗血清アルブミン結合変異体 - Google Patents
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37339710P | 2010-08-13 | 2010-08-13 | |
| US61/373,397 | 2010-08-13 | ||
| PCT/EP2011/063999 WO2012020143A1 (en) | 2010-08-13 | 2011-08-12 | Improved anti-serum albumin binding variants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013538566A true JP2013538566A (ja) | 2013-10-17 |
| JP2013538566A5 JP2013538566A5 (OSRAM) | 2014-09-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013523643A Pending JP2013538566A (ja) | 2010-08-13 | 2011-08-12 | 改良された抗血清アルブミン結合変異体 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US9012609B2 (OSRAM) |
| EP (1) | EP2603522A1 (OSRAM) |
| JP (1) | JP2013538566A (OSRAM) |
| WO (1) | WO2012020143A1 (OSRAM) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110049997A (zh) * | 2016-12-07 | 2019-07-23 | 埃博灵克斯股份有限公司 | 改进的血清白蛋白结合免疫球蛋白单可变结构域 |
| US11414481B2 (en) | 2017-01-17 | 2022-08-16 | Ablynx N.V. | Serum albumin binders |
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| CA2989966C (en) | 2015-08-20 | 2024-04-30 | Albumedix A/S | Albumin variants and conjugates |
| US11142569B2 (en) * | 2015-11-13 | 2021-10-12 | Ablynx N.V. | Serum albumin-binding immunoglobulin variable domains |
| AU2017268394A1 (en) | 2016-05-18 | 2019-01-03 | Modernatx, Inc. | Polynucleotides encoding relaxin |
| HRP20250319T1 (hr) | 2017-02-16 | 2025-05-09 | Sonnet BioTherapeutics, Inc. | Fuzijski proteini s domenom za vezanje na albumin |
| AR131869A1 (es) | 2023-02-17 | 2025-05-07 | Ablynx Nv | POLIPÉPTIDOS QUE SE UNEN AL RECEPTOR DE Fc NEONATAL |
| US12134635B1 (en) | 2023-12-29 | 2024-11-05 | Sonnet BioTherapeutics, Inc. | Interleukin 18 (IL-18) variants and fusion proteins comprising same |
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| CN110049997A (zh) * | 2016-12-07 | 2019-07-23 | 埃博灵克斯股份有限公司 | 改进的血清白蛋白结合免疫球蛋白单可变结构域 |
| KR20190091524A (ko) * | 2016-12-07 | 2019-08-06 | 아블린쓰 엔.브이. | 개선된 혈청 알부민 결합성 면역글로불린 단일 가변 도메인 |
| JP2020511113A (ja) * | 2016-12-07 | 2020-04-16 | アブリンクス エン．ヴェー． | 改善された血清アルブミン結合性免疫グロブリン単一可変ドメイン |
| US11414480B2 (en) | 2016-12-07 | 2022-08-16 | Ablynx N.V. | Serum albumin binding immunoglobulin single variable domains |
| JP2023109939A (ja) * | 2016-12-07 | 2023-08-08 | アブリンクス エン．ヴェー． | 改善された血清アルブミン結合性免疫グロブリン単一可変ドメイン |
| CN110049997B (zh) * | 2016-12-07 | 2023-09-22 | 埃博灵克斯股份有限公司 | 改进的血清白蛋白结合免疫球蛋白单可变结构域 |
| KR102616835B1 (ko) | 2016-12-07 | 2023-12-22 | 아블린쓰 엔.브이. | 개선된 혈청 알부민 결합성 면역글로불린 단일 가변 도메인 |
| JP7417421B2 (ja) | 2016-12-07 | 2024-01-18 | アブリンクス エン．ヴェー． | 改善された血清アルブミン結合性免疫グロブリン単一可変ドメイン |
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| US11897944B2 (en) | 2017-01-17 | 2024-02-13 | Ablynx N.V. | Immunoglobulin single variable domain (ISVD) capable of binding to serum albumin |
Also Published As
| Publication number | Publication date |
|---|---|
| US20160052998A1 (en) | 2016-02-25 |
| WO2012020143A1 (en) | 2012-02-16 |
| US20130202597A1 (en) | 2013-08-08 |
| US9012609B2 (en) | 2015-04-21 |
| EP2603522A1 (en) | 2013-06-19 |
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