JP2013528622A5 - - Google Patents
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- Publication number
- JP2013528622A5 JP2013528622A5 JP2013513360A JP2013513360A JP2013528622A5 JP 2013528622 A5 JP2013528622 A5 JP 2013528622A5 JP 2013513360 A JP2013513360 A JP 2013513360A JP 2013513360 A JP2013513360 A JP 2013513360A JP 2013528622 A5 JP2013528622 A5 JP 2013528622A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- cadherin
- optionally
- composition according
- der
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 18
- 102100024155 Cadherin-11 Human genes 0.000 claims 12
- 108010000953 osteoblast cadherin Proteins 0.000 claims 12
- 239000005557 antagonist Substances 0.000 claims 6
- 206010061218 Inflammation Diseases 0.000 claims 4
- 230000004054 inflammatory process Effects 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 208000035475 disorder Diseases 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 102000000905 Cadherin Human genes 0.000 claims 2
- 108050007957 Cadherin Proteins 0.000 claims 2
- 210000004204 blood vessel Anatomy 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 210000000056 organ Anatomy 0.000 claims 2
- 210000004303 peritoneum Anatomy 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 238000001356 surgical procedure Methods 0.000 claims 2
- 102000053642 Catalytic RNA Human genes 0.000 claims 1
- 108090000994 Catalytic RNA Proteins 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 241000255925 Diptera Species 0.000 claims 1
- 206010018364 Glomerulonephritis Diseases 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 208000034189 Sclerosis Diseases 0.000 claims 1
- 208000035868 Vascular inflammations Diseases 0.000 claims 1
- 210000001015 abdomen Anatomy 0.000 claims 1
- 230000000692 anti-sense effect Effects 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 210000003169 central nervous system Anatomy 0.000 claims 1
- 238000000502 dialysis Methods 0.000 claims 1
- 208000007784 diverticulitis Diseases 0.000 claims 1
- 238000005553 drilling Methods 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 229940012356 eye drops Drugs 0.000 claims 1
- 239000003885 eye ointment Substances 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 239000003018 immunosuppressive agent Substances 0.000 claims 1
- 229940125721 immunosuppressive agent Drugs 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 201000006334 interstitial nephritis Diseases 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 208000009091 myxoma Diseases 0.000 claims 1
- 108091092562 ribozyme Proteins 0.000 claims 1
- 150000003384 small molecules Chemical group 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 125000002345 steroid group Chemical group 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35150510P | 2010-06-04 | 2010-06-04 | |
| US61/351,505 | 2010-06-04 | ||
| PCT/US2011/039002 WO2011153397A2 (en) | 2010-06-04 | 2011-06-03 | Treatment of inflammatory disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013528622A JP2013528622A (ja) | 2013-07-11 |
| JP2013528622A5 true JP2013528622A5 (enExample) | 2014-07-24 |
Family
ID=45067307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013513360A Pending JP2013528622A (ja) | 2010-06-04 | 2011-06-03 | 炎症性障害の処置 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20130209476A1 (enExample) |
| EP (1) | EP2575883B1 (enExample) |
| JP (1) | JP2013528622A (enExample) |
| AU (1) | AU2011261323A1 (enExample) |
| CA (1) | CA2805270C (enExample) |
| IL (1) | IL223385B (enExample) |
| WO (1) | WO2011153397A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130068691A1 (en) * | 2011-08-05 | 2013-03-21 | Henry John Smith | Targeted apheresis for the treatment of rheumatoid arthritis and immune disorders |
| WO2016100301A1 (en) * | 2014-12-15 | 2016-06-23 | The Brigham And Women's Hospital, Inc. | Use of cadherin-11 antagonists to treat obesity-associated conditions and other metabolic disorders |
| US20200181649A1 (en) * | 2016-07-14 | 2020-06-11 | University Of Delaware | Hybrid formulation of responsive polymeric nanocarriers for therapeutic and diagnostic delivery |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5610281A (en) | 1994-05-03 | 1997-03-11 | Brigham & Women's Hospital, Inc. | Antibodies for modulating heterotypic E-cadherin interactions with human T lymphocytes |
| US7481999B2 (en) * | 1998-05-05 | 2009-01-27 | Adherex Technologies, Inc. | Compounds and methods for modulating OB-cadherin-mediated function |
| US6787136B1 (en) * | 1999-09-03 | 2004-09-07 | The Brigham And Women's Hospital, Inc. | Methods and compositions for treatment of inflammatory disease using cadherin-11 modulating agents |
| CN101613405A (zh) * | 2002-06-06 | 2009-12-30 | 肿瘤疗法科学股份有限公司 | 与人结肠癌相关的基因和多肽 |
| MXPA05011409A (es) * | 2003-04-23 | 2005-12-12 | Medarex Inc | Composiciones y metodos para la terapia de enfermedad inflamatoria intestinal. |
| US20050002919A1 (en) * | 2003-06-09 | 2005-01-06 | The Brigham And Women's Hospital, Inc. | Cadherin directed molecular and cellular localization |
| MY162179A (en) * | 2004-04-01 | 2017-05-31 | Elan Pharm Inc | Steroid sparing agents and methods of using same |
| WO2008140774A2 (en) * | 2007-05-08 | 2008-11-20 | Picobella Llc | Methods for diagnosing and treating prostate and lung cancer |
| WO2009101059A2 (en) * | 2008-02-11 | 2009-08-20 | Novartis Ag | Methods of using cadherin 11 (cdh11) antagonists |
| US8802687B2 (en) * | 2009-02-09 | 2014-08-12 | Georgetown University | Cadherin-11 inhibitors and methods of use thereof |
| US8877188B2 (en) * | 2010-05-04 | 2014-11-04 | The Brigham And Women's Hospital, Inc. | Detection and treatment of non-dermal fibrosis |
| CA2805267C (en) * | 2010-05-04 | 2019-07-30 | The Brigham And Women's Hospital, Inc. | Detection and treatment of fibrosis |
-
2011
- 2011-06-03 CA CA2805270A patent/CA2805270C/en active Active
- 2011-06-03 US US13/702,018 patent/US20130209476A1/en not_active Abandoned
- 2011-06-03 EP EP11790443.3A patent/EP2575883B1/en active Active
- 2011-06-03 WO PCT/US2011/039002 patent/WO2011153397A2/en not_active Ceased
- 2011-06-03 AU AU2011261323A patent/AU2011261323A1/en not_active Abandoned
- 2011-06-03 JP JP2013513360A patent/JP2013528622A/ja active Pending
-
2012
- 2012-12-02 IL IL223385A patent/IL223385B/en active IP Right Grant
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