JP2013525473A5 - - Google Patents
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- Publication number
- JP2013525473A5 JP2013525473A5 JP2013508559A JP2013508559A JP2013525473A5 JP 2013525473 A5 JP2013525473 A5 JP 2013525473A5 JP 2013508559 A JP2013508559 A JP 2013508559A JP 2013508559 A JP2013508559 A JP 2013508559A JP 2013525473 A5 JP2013525473 A5 JP 2013525473A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- ortho
- meta
- optionally substituted
- trifluoromethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(*)(c1ccc(ccc(*)n2)c2c1O)N* Chemical compound *C(*)(c1ccc(ccc(*)n2)c2c1O)N* 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUP1000243 | 2010-05-06 | ||
| HU1000243A HUP1000243A2 (en) | 2010-05-06 | 2010-05-06 | 8-hidroxy-quinoline derivatives |
| PCT/HU2011/000043 WO2011148208A1 (en) | 2010-05-06 | 2011-05-06 | 8-hydroxy-quinoline derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013525473A JP2013525473A (ja) | 2013-06-20 |
| JP2013525473A5 true JP2013525473A5 (OSRAM) | 2014-06-26 |
| JP5812541B2 JP5812541B2 (ja) | 2015-11-17 |
Family
ID=89989711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508559A Active JP5812541B2 (ja) | 2010-05-06 | 2011-05-06 | ８−ヒドロキシキノリン誘導体 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8871937B2 (OSRAM) |
| EP (1) | EP2566849B1 (OSRAM) |
| JP (1) | JP5812541B2 (OSRAM) |
| KR (1) | KR101837974B1 (OSRAM) |
| CN (1) | CN102985407B (OSRAM) |
| AU (1) | AU2011256989B2 (OSRAM) |
| CA (1) | CA2798419C (OSRAM) |
| CY (1) | CY1122426T1 (OSRAM) |
| DK (1) | DK2566849T3 (OSRAM) |
| EA (1) | EA021026B1 (OSRAM) |
| ES (1) | ES2761832T3 (OSRAM) |
| HR (1) | HRP20192278T1 (OSRAM) |
| HU (2) | HUP1000243A2 (OSRAM) |
| MX (1) | MX337999B (OSRAM) |
| NZ (1) | NZ603967A (OSRAM) |
| PL (1) | PL2566849T3 (OSRAM) |
| PT (1) | PT2566849T (OSRAM) |
| RS (1) | RS59678B1 (OSRAM) |
| SI (1) | SI2566849T1 (OSRAM) |
| SM (1) | SMT201900710T1 (OSRAM) |
| WO (1) | WO2011148208A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP1500098A2 (hu) * | 2015-03-09 | 2016-09-28 | Avidin Kft | 8-hidroxikinolin származékok új enantiomerjei és szintézisük |
| WO2017066245A1 (en) * | 2015-10-12 | 2017-04-20 | Health Research, Inc. | Methods for inducing apoptosis in cancer cells |
| CN105367553A (zh) * | 2015-12-04 | 2016-03-02 | 广东工业大学 | 一种他克林-8-羟（胺）基喹啉衍生物及其应用 |
| HUP1600234A2 (en) | 2016-04-05 | 2017-12-28 | Mta Termeszettudomanyi Kutatokoezpont | Mdr-reversing 8-hydroxy-quinoline derivatives |
| WO2024073624A2 (en) * | 2022-09-28 | 2024-04-04 | The Research Foundation For The State University Of New York | Antiproliferative betti bases and prodrugs thereof |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6544972B1 (en) | 1997-09-25 | 2003-04-08 | Regents Of The University Of Minnesota | Methods of limiting apoptosis of cells |
| US6184210B1 (en) | 1997-10-10 | 2001-02-06 | Cytovia, Inc. | Dipeptide apoptosis inhibitors and the use thereof |
| JP2002501018A (ja) | 1998-01-26 | 2002-01-15 | マイトコー | ミトコンドリア関連疾患を処置するためのミトコンドリア保護剤 |
| US6737511B1 (en) | 1999-08-16 | 2004-05-18 | The United States Of America As Represented By The Department Of Health And Human Services | Receptor-mediated uptake of an extracellular BCL-xL fusion protein inhibits apoptosis |
| EA200200301A1 (ru) | 1999-08-27 | 2002-08-29 | Сайтовиэ, Инк. | ЗАМЕЩЕННЫЕ α-ГИДРОКСИКИСЛОТЫ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБ ИНГИБИРОВАНИЯ КЛЕТОЧНОЙ ГИБЕЛИ НА КЛЕТОЧНОМ ИЛИ ТКАНЕВОМ УРОВНЕ, СПОСОБ ЛЕЧЕНИЯ ИЛИ ОБЛЕГЧЕНИЯ СОСТОЯНИЯ ПРИ ГИБЕЛИ КЛЕТОК У ЖИВОТНОГО, СПОСОБ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ РАЗЛИЧНЫХ БОЛЕЗНЕЙ |
| US6890896B1 (en) | 1999-11-18 | 2005-05-10 | Ceremedix, Inc. | Compositions and methods for counteracting effects of reactive oxygen species and free radicals |
| US6531464B1 (en) | 1999-12-07 | 2003-03-11 | Inotek Pharmaceutical Corporation | Methods for the treatment of neurodegenerative disorders using substituted phenanthridinone derivatives |
| US6476048B1 (en) | 1999-12-07 | 2002-11-05 | Inotek Pharamaceuticals Corporation | Substituted phenanthridinones and methods of use thereof |
| US6534651B2 (en) | 2000-04-06 | 2003-03-18 | Inotek Pharmaceuticals Corp. | 7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof |
| GB0011095D0 (en) | 2000-05-08 | 2000-06-28 | Black James Foundation | astrin and cholecystokinin receptor ligands (III) |
| US6521617B2 (en) | 2000-10-13 | 2003-02-18 | The Johns Hopkins University | Treatment of apoptotic cell death |
| AU2002239595A1 (en) | 2000-12-15 | 2002-06-24 | Mitokor | Compounds for altering mitochondrial function and cellular responses |
| US7601846B2 (en) | 2001-06-26 | 2009-10-13 | The Regents Of The University Of California | Compounds having activity as inhibitors of apoptosis |
| US7604989B2 (en) | 2001-07-10 | 2009-10-20 | Johns Hopkins University | Inhibition of apoptosis process and improvement of cell performance |
| DE10144153A1 (de) | 2001-09-07 | 2003-03-27 | Newfrey Llc | Halteclip mit versetzten Rastfingern |
| EA200401070A1 (ru) | 2002-02-13 | 2005-02-24 | Бет Изрейэл Диконисс Медикал Сентер, Инк. | Способы лечения сосудистых заболеваний |
| JP2007501857A (ja) | 2003-02-28 | 2007-02-01 | イノテック ファーマシューティカルズ コーポレーション | 四環系ベンズアミド誘導体およびその使用方法 |
| US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| JP4824566B2 (ja) | 2003-05-28 | 2011-11-30 | エーザイ インコーポレーテッド | Ｐａｒｐを阻害するための化合物、方法、および医薬組成物 |
| CA2971928C (en) | 2004-01-23 | 2019-01-08 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
| TWI375673B (en) | 2005-04-11 | 2012-11-01 | Abbott Lab | 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors |
| TW200736229A (en) | 2005-11-15 | 2007-10-01 | Abbott Lab | Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors |
| US7528174B2 (en) | 2006-01-06 | 2009-05-05 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Selective targeting agents for mitochondria |
| AU2007280984A1 (en) * | 2006-07-25 | 2008-02-07 | Envivo Pharmaceutical Inc. | Quinoline derivatives |
| EP3085367A3 (en) * | 2007-03-20 | 2017-01-25 | Brandeis University | Compositions for the diagnosis, treatment, and prevention of amyotrophic lateral sclerosis and related |
| US8183236B2 (en) * | 2007-04-12 | 2012-05-22 | University Of Southern California | Compounds with HIV-1 integrase inhibitory activity and use thereof as anti-HIV/AIDS therapeutics |
| CA2687187A1 (en) | 2007-05-25 | 2008-12-18 | Burnham Institute For Medical Research | Inhibitors of thapsigargin-induced cell death |
| US8138356B2 (en) * | 2007-10-16 | 2012-03-20 | Angiogeney, Inc. | Chemical inhibitors of inhibitors of differentiation |
| US10301265B2 (en) * | 2008-05-28 | 2019-05-28 | Virginia I. Roxas-Duncan | Small molecule inhibitors of botulinum neurotoxins |
| CA2786289A1 (en) * | 2010-01-06 | 2011-07-14 | Joseph P. Errico | Methods and compositions of targeted drug development |
| US8658170B2 (en) * | 2010-01-06 | 2014-02-25 | Joseph P. Errico | Combination therapy with MDM2 and EFGR inhibitors |
-
2010
- 2010-05-06 HU HU1000243A patent/HUP1000243A2/hu unknown
-
2011
- 2011-05-06 HU HUE11752335A patent/HUE050886T2/hu unknown
- 2011-05-06 EA EA201270787A patent/EA021026B1/ru unknown
- 2011-05-06 US US13/696,541 patent/US8871937B2/en active Active
- 2011-05-06 MX MX2012012883A patent/MX337999B/es active IP Right Grant
- 2011-05-06 SM SM20190710T patent/SMT201900710T1/it unknown
- 2011-05-06 RS RS20191622A patent/RS59678B1/sr unknown
- 2011-05-06 ES ES11752335T patent/ES2761832T3/es active Active
- 2011-05-06 SI SI201131826T patent/SI2566849T1/sl unknown
- 2011-05-06 PT PT117523357T patent/PT2566849T/pt unknown
- 2011-05-06 WO PCT/HU2011/000043 patent/WO2011148208A1/en not_active Ceased
- 2011-05-06 EP EP11752335.7A patent/EP2566849B1/en active Active
- 2011-05-06 NZ NZ603967A patent/NZ603967A/en not_active IP Right Cessation
- 2011-05-06 DK DK11752335.7T patent/DK2566849T3/da active
- 2011-05-06 PL PL11752335T patent/PL2566849T3/pl unknown
- 2011-05-06 HR HRP20192278TT patent/HRP20192278T1/hr unknown
- 2011-05-06 KR KR1020127030702A patent/KR101837974B1/ko active Active
- 2011-05-06 JP JP2013508559A patent/JP5812541B2/ja active Active
- 2011-05-06 CN CN201180033524.5A patent/CN102985407B/zh active Active
- 2011-05-06 CA CA2798419A patent/CA2798419C/en active Active
- 2011-05-06 AU AU2011256989A patent/AU2011256989B2/en not_active Ceased
-
2019
- 2019-12-17 CY CY20191101327T patent/CY1122426T1/el unknown
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