JP2013520960A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013520960A5 JP2013520960A5 JP2012540193A JP2012540193A JP2013520960A5 JP 2013520960 A5 JP2013520960 A5 JP 2013520960A5 JP 2012540193 A JP2012540193 A JP 2012540193A JP 2012540193 A JP2012540193 A JP 2012540193A JP 2013520960 A5 JP2013520960 A5 JP 2013520960A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- amount
- cell
- human subject
- degradation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30992710P | 2010-03-03 | 2010-03-03 | |
| US61/309,927 | 2010-03-03 | ||
| PCT/JP2011/055570 WO2011108766A1 (en) | 2010-03-03 | 2011-03-03 | METHOD FOR DIAGNOSING A PROTEIN MISFOLDING DISEASE USING NERVE CELLS DERIVED FROM iPS CELLS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013520960A JP2013520960A (ja) | 2013-06-10 |
| JP2013520960A5 true JP2013520960A5 (https=) | 2014-06-26 |
| JP5846608B2 JP5846608B2 (ja) | 2016-01-20 |
Family
ID=44542394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540193A Expired - Fee Related JP5846608B2 (ja) | 2010-03-03 | 2011-03-03 | iPS細胞由来の神経細胞を用いた蛋白質ミスフォールディング病の診断方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US9097727B2 (https=) |
| JP (1) | JP5846608B2 (https=) |
| WO (1) | WO2011108766A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8642334B2 (en) | 2009-02-17 | 2014-02-04 | Memorial Sloan Kettering Cancer Center | Methods of neural conversion of human embryonic stem cells |
| US9453198B2 (en) * | 2010-05-25 | 2016-09-27 | Memorial Sloan Kettering Cancer Center | Method of nociceptor differentiation of human embryonic stem cells and uses thereof |
| PT2773748T (pt) | 2011-11-04 | 2020-03-26 | Memorial Sloan Kettering Cancer Center | Neurónios dopaminérgicos (da) do mesencéfalo para enxerto |
| EP2829605B1 (en) * | 2012-03-21 | 2019-05-08 | Kyoto University | Method for screening therapeutic and/or prophylactic agents for alzheimer's disease |
| EP3498824A1 (en) | 2013-04-26 | 2019-06-19 | Memorial Sloan-Kettering Cancer Center | Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells |
| CA2957071A1 (en) * | 2014-08-04 | 2016-02-11 | University Of Kansas | Mammalian pluripotent stem cells, methods for their production, and uses thereof |
| EP3315604A4 (en) | 2015-06-25 | 2018-12-26 | Kaneka Corporation | Liquid injection method |
| US20210123025A1 (en) * | 2018-07-03 | 2021-04-29 | Universidad Del País Vasco - Euskal Herriko Unibertsitatea | Cellular aggregates for use in vascularisation therapy |
| WO2020165615A1 (en) | 2019-02-14 | 2020-08-20 | Omnion Research International D.O.O. | Method of transformation of hair folicle cells into neurons, method and scale for estimating risk for onset of a particular brain disease |
| JP7333579B2 (ja) * | 2019-05-08 | 2023-08-25 | 国立大学法人東京工業大学 | アルツハイマー疾患モデル神経細胞及びその製造方法、並びにその神経細胞を用いたアルツハイマー病作用薬物のスクリーニング方法 |
| JP7678577B2 (ja) | 2019-05-31 | 2025-05-16 | 国立大学法人京都大学 | 情報処理装置、情報処理方法、及びプログラム |
| JPWO2020241772A1 (https=) * | 2019-05-31 | 2020-12-03 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003235113A1 (en) * | 2002-04-26 | 2003-11-10 | Riken | Method of measuring neprilysin activity |
| ZA200401646B (en) * | 2003-03-12 | 2004-06-07 | Reliance Life Sciences Pvt Ltd | Derivation of terminally differentiated dopaminergic neurons from human embryonic stem cells. |
| WO2004081172A2 (en) * | 2003-03-12 | 2004-09-23 | Reliance Life Sciences Pvt. Ltd. | Derivation of terminally differentiated dopaminergic neurons from human embryonic stem cells |
| US8669048B2 (en) * | 2008-06-24 | 2014-03-11 | Parkinson's Institute | Pluripotent cell lines and methods of use thereof |
-
2011
- 2011-03-03 WO PCT/JP2011/055570 patent/WO2011108766A1/en not_active Ceased
- 2011-03-03 JP JP2012540193A patent/JP5846608B2/ja not_active Expired - Fee Related
- 2011-03-03 US US13/582,403 patent/US9097727B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013520960A5 (https=) | ||
| Frontzkowski et al. | Earlier Alzheimer’s disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading | |
| Onos et al. | Enhancing face validity of mouse models of Alzheimer’s disease with natural genetic variation | |
| Mander et al. | Sleep: a novel mechanistic pathway, biomarker, and treatment target in the pathology of Alzheimer's disease? | |
| Gaiteri et al. | Genetic variants in Alzheimer disease—molecular and brain network approaches | |
| Cushing et al. | Impaired hippocampal-cortical interactions during sleep in a mouse model of Alzheimer’s disease | |
| Marras et al. | Parkinson's disease subtypes: lost in translation? | |
| Gómez-Sintes et al. | Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders | |
| EA201590175A1 (ru) | Скрининг, диагностика и прогнозирование аутизма и других нарушений развития | |
| CN103961113A (zh) | 用于基于用户的行为测量压力的设备和方法 | |
| Ogonowski et al. | Systematic review: microRNAs as potential biomarkers in mild cognitive impairment diagnosis | |
| JP2015511721A5 (https=) | ||
| Castillo-Mariqueo et al. | Impact of Behavioral Assessment and Re-Test as Functional Trainings That Modify Survival, Anxiety and Functional Profile (Physical Endurance and Motor Learning) of Old Male and Female 3xTg-AD Mice and NTg Mice with Normal Aging | |
| Falkenhain et al. | A pilot study investigating the effects of voluntary exercise on capillary stalling and cerebral blood flow in the APP/PS1 mouse model of Alzheimer’s disease | |
| Qiu et al. | Alzheimer's disease progression model based on integrated biomarkers and clinical measures | |
| Vandenberghe | The relationship between amyloid deposition, neurodegeneration, and cognitive decline in dementia | |
| Baxter et al. | Investigation of associations between Piezo1 mechanoreceptor gain-of-function variants and glaucoma-related phenotypes in humans and mice | |
| Kuang et al. | Default mode network analysis of APOE genotype in cognitively unimpaired subjects based on persistent homology | |
| Castillo-Mariqueo et al. | Translational modeling of psychomotor function in normal and AD-pathological aging with special concerns on the effects of social isolation | |
| Ren et al. | Leveraging diverse regulated cell death patterns to identify diagnosis biomarkers for Alzheimer’s disease | |
| Jiao et al. | Temporal dynamics and composition of ocular surface microbiota in C57BL/6J mice: uncovering a 12h ultradian rhythm | |
| Platt et al. | FDG–PET imaging, EEG and sleep phenotypes as translational biomarkers for research in Alzheimer's disease | |
| Dehkordi et al. | Identification of markers for neurescence through transcriptomic profiling of postmortem human brains | |
| Stevenson et al. | Systematic analysis of goal‐related movement sequences during maternal behaviour in a female mouse model for Rett syndrome | |
| Østergaard et al. | Classification of α-synuclein-induced changes in the AAV α-synuclein rat model of Parkinson’s disease using electrophysiological measurements of visual processing |