JP2013132332A - Medical solution container with hollow needle or medical solution container with hollow needle filled with medical solution, body fluid collection container with hollow needle, accumulation carrier mounted with a plurality of these containers, accumulation carrier assembly, continuous injection device, continuous body fluid collection device, and method for producing accumulation carrier - Google Patents

Abstract

PROBLEM TO BE SOLVED: To avoid inconvenience of air removal and handling of a container for storing medical solution or the like when performing injection or body fluid collection, to perform accumulative storage or continuous use by simplifying the configuration and achieving miniaturization and thinning, to reduce the cost by reducing manufacturing manhours and materials, and to improve safety and easiness in use.SOLUTION: The medical solution container with a hollow needle, the medical solution container with a hollow needle filled with medical solution, or the body fluid collection container with a hollow needle is a storage chamber having the needle with a hollow communication hole in which the medical solution is stored or body fluid is to be stored. The basal plane thereof has a rigid base plate part with the needle, and a chamber wall of the storage chamber other than the basal plane has a flexible and elastic part for expanding/contracting the storage chamber in the direction same as the direction of inserting or withdrawing the needle according to a pushing pressure or a pulling pressure.

Description

The present invention relates to a liquid medicine container with a hollow needle for injection and body fluid collection, a liquid medicine container containing a liquid medicine, a body fluid collection container, an integrated carrier for carrying and storing the same, and a continuous carrier using the same. The present invention relates to a method for producing an injection device and a continuous body fluid collecting device integrated carrier.

Conventionally, there have been many proposals for injection devices and body fluid collection devices, which are manufactured and used. Both are characterized by being used in a single-use manner to prevent infection to non-patients.
Under such circumstances, a simple device with a low cost and a safe device have been demanded, and new proposals have been made one after another.
13 to 15 show a conventionally proposed injection device.
13A of FIG. 13 is a diagram of the disposable injection device disclosed in Patent Document 1. In FIG. In addition to Patent Document 1, many similar disposable injection devices have been proposed. This type of disposable injection device is generally made of a resin having a complicated structure, but it can be said that it is not desirable to dispose of it from the viewpoint of cost and waste of resources.

FIG. 14 is a view of an injection device different from that shown in Patent Document 2. In FIG. 14-A shows the state before injection and 14-B shows the state during injection. In paragraph 0019 of this document, there is the following description about the configuration before injection.
The lower part of the chemical chamber 11 provided in the cylinder 10 is joined to the upper part of the chemical chamber and the chemical solution injection part 20 sealed with a bottom portion 14 provided with a needle support 13 for holding the needle 12 communicating with the chemical chamber 11 and the chemical solution It consists of a circular outer frame 30 whose lower part surrounding the injection part 20 is opened, and an elastic material disk 40 having a skin contact surface 45 that comes into contact with the skin. A configuration is adopted in which the needle support 13 of the drug solution injector 20 and the tip portion 15 of the needle 12 held by the needle support are embedded in an elastic material disk while being fitted in the frame 30.

Further, in paragraph numbers 0022 to 0025, there are states during injection and the subsequent description.
Since the skin contact surface 45 of the medicinal solution injection device 1 is brought into close contact with the injection site of the body and is slapped (tapped) by hand, the elastic material disc 40 is in a cushioned state due to its elasticity, so that the needle 12 is exposed to the outside. A needle sticks into the injection site of the body, and the chemical is instantaneously injected into the body. In the state where the administration of the chemical solution is completed, the elastic material disk 40 returns to its original state due to the repulsive elastic force, and the needle comes out of the injection site of the body and is buried in the elastic material disk 40 so that it can be disposed of.

As described above, the slap operation with a needle sticking operation is a momentary impact, and has a great drawback that the operation varies. The configuration of the elastic material disk 40 and the circular outer frame 30 is also larger than that of a small needle portion, and it is difficult to configure a small and thin configuration. In addition, the complicated configuration increases the cost and is not necessary for the disposable use of the syringe. In this proposal, the invention is not yet completed, and the injection is not actually completed. Although it is realized that the needle is exposed to the outside from the skin contact surface 45 at the moment of the slap operation and pierces the injection site of the body, there is no description about means for discharging the drug solution from the drug solution chamber. In the figure of the state during the injection of 13-B, the elastic material disk 40 is recessed, but the chemical chamber is not contracted. In order to discharge the chemical solution in such a state, the elastic material disc 40 is recessed, and the air in the space between the elastic material disc 40 and the disc outer frame 30 is compressed so that the pressing force is transmitted to the chemical solution chamber. It is necessary to make a communication hole between the chemical chamber and the space, but there is no description. If there is no contraction of the chemical solution chamber, the discharge can be considered due to the impact of the slap operation, but the negative pressure of the chemical solution chamber due to the discharge obstructs and almost no discharge is possible.
Therefore, if the fluid chamber is made flexible so that it can be discharged without a communication hole, the elastic material disc 40 and the fluid chamber contract at the time of slap. Depending on the situation, the needle may come out, the drug solution may not come out, or the operation may be delicate, which is actually very difficult. In this proposal, it is certain that the needle comes out, but in order for the chemical solution to come out, it is only possible to provide a communication hole.

FIG. 15 is a diagram of another injection device disclosed in Patent Document 3. As shown in FIG.
In paragraph 0011 of this document, an instrument for introducing a substance into a patient's skin has a housing with a central opening and a flat member disposed within the central opening of the housing. The flat member has an inner surface and an outer surface, and a plurality of microneedles extend from the outer surface. The flat member further has at least one opening extending through the flat member to the inner surface or the outer surface and at least one cannula provided on the inner surface. A flexible cover is coupled to the housing, covering the central opening and spaced apart from the flat member to define a cavity within the housing. A bag containing at least one material is disposed within the cavity of the housing between the flat member and the flexible cover. The bag can be pierced by a cannula and can crush the flexible cover to dispense material through the opening into the microneedles.
In paragraph 0012, there is a description that the flexible cover can take two positions, a first position and a second position.
Further, paragraph number 0013 describes that sufficient pressure is applied to the flexible cover to rupture the bag and dispense the substance into the microneedles.
In the detailed description of the embodiments, only those with cannulas are described. Even in the scope of claims, claims 21 and 30 are broadly claimed to the extent that there is no cannula corresponding to paragraphs 0012 and 0013, but in the final patent No. 4815095, , All with certain restrictions on the cannula.
The main point of the configuration in the above proposal is to have one container by a housing having a flexible cover and a microneedle at the bottom, and a bag for containing a chemical solution stored in the container. The first feature is the double configuration of the two containers with the container. A second feature is to have a cannula for breaking the bag.

The first feature of the container double configuration is that the outer container with the needle is discharged from the inner container bag, filling the outer container, which enters the body through the needle. Therefore, as a matter of course, the inside of the outer container needs to be in an air-bleeded state without air. In addition to ensuring that the inner container bag containing the injection substance is filled with the substance alone and venting, the outer container is also vented, which requires the extra time and effort. It is necessary that the needle tip is always in a sealed state. If the outer container is filled with substance from the beginning, the substance fills up to the tip of the needle, so there is no air entering from the needle hole. The needle tip may be open. The outer container is initially not filled with material, which is very different from the double container configuration, which has such a major disadvantage.

Furthermore, in the above-described double configuration, there are great inconveniences in usage other than air bleeding. In use, the container is put on the body, pressure is applied, the needle is stabbed, and at the same time the bag is broken to give the injection substance, but the needle tip is sealed so that the needle is put out first. You cannot take off the lid. This is because air enters from the needle hole at the moment the lid is removed. In order to prevent air from entering, first, it is necessary to first tear the bag first by pressing pressure and fill the needle hole with the substance.
Or it must be constructed so that it presses against the body and causes the needle lid to break with the needle.
In addition, breaking the lid with a needle may break the lid with a small impact during storage and transportation, which may cause air to enter the outer container. This means cannot be used in practice. . Therefore, before use, the user breaks the bag by pressing pressure, fills the outer container with the substance, then removes the needle lid and presses against the body, which is heavy in managing the usage. Is necessary and is extremely inconvenient.
Furthermore, in the first feature, the manufacturing process is naturally long, and the complicated structure increases the cost, which is a great disadvantage.
Also, breaking the bag without a cannula requires a large pressing force due to the flexibility of the bag, and the impact at the moment when the bag is broken does not cause a slow injection of the substance but causes a variation in the pressing pressure. On the contrary, if the bag is easily torn, there is a concern that it may be torn during storage or transportation, which is also a difficult inconvenience.

Furthermore, having a cannula that breaks the bag, which is the second feature, breaks the bag and opens a hole, but the structure is complicated and the manufacturing process is naturally long, and the structure is complicated and the cost is high. At the moment when a hole is made in the bag with a cannula, there will be variations in the push state where the bag will break because the bag will escape against the pressure.

In addition, the double structure of the container and the cannula are unnecessarily difficult to dispose of, and the thickness of the apparatus is increased accordingly, and the housing needs to have a robust part, which is not suitable for accumulating a plurality of apparatuses by folding them. There is an inconvenience.

Special table 2006-525830 JP2007-14594 Special table 2004-503341

The object of the present invention is to avoid the inconvenience of air venting and handling of a container for storing a chemical solution, etc., simplifying the configuration, enabling miniaturization and thinning, enabling integrated storage and continuous use, and reducing the number of manufacturing steps and materials. Reduced cost by reducing cost, safe and easy use chemical container with hollow needle or container with chemical liquid with hollow needle containing chemical liquid, body fluid collection container with hollow needle, integrated carrier equipped with multiple of these containers, An integrated carrier assembly, a continuous injection device, and a continuous body fluid collection device are provided.

The chemical solution container with a hollow needle of the present invention or a container with a chemical solution with a hollow needle in which a chemical solution is put therein, and a body fluid collection container with a hollow needle are equipped with a needle having a hollow communication hole in which a chemical solution is stored or a body fluid is stored. The bottom surface of the storage chamber has a rigid substrate portion with a needle, and the storage chamber is pressed or pulled in the same direction as the direction in which the needle is inserted and removed on the chamber wall other than the bottom surface. A flexible expansion / contraction part is provided for expanding and contracting according to pressure. Further, the present invention is characterized in that the aggregate is formed on the integrated carrier.

The invention according to claim 1 is a chemical container with a hollow needle, a container with a chemical liquid with a hollow needle or a body fluid collecting container with a hollow needle in which a chemical liquid is put, and is a hollow container in which a chemical liquid is stored or a body fluid is stored. A storage chamber provided with a needle having a communication hole, the bottom surface of the storage chamber has a rigid substrate portion provided with the needle, and the chamber wall other than the bottom surface of the storage chamber has a direction for inserting and removing the needle The storage chamber is expanded and contracted in the direction of the same direction according to the pulling pressure or the pressing pressure to be a flexible expansion / contraction section for collecting and storing body fluid or injecting chemical liquid.

Invention of Claim 2 is the flexible expansion-contraction part of the said storage chamber in the chemical | medical solution container with a hollow needle of Claim 1, or the container with a chemical solution with a hollow needle which put the chemical | medical solution in this, or the bodily fluid collection container with a hollow needle. The chamber wall surface is a surface that moves while deforming in the direction of the pulling pressure or the pressing pressure when it is on the upper surface opposite to the bottom surface, or can be expanded and contracted when it is on the side surface rising from the bottom surface. It is characterized by a surface that is shaped like a bellows.

According to a third aspect of the present invention, in the chemical liquid container with a hollow needle according to the first aspect or the second aspect, or the container with a chemical liquid with a hollow needle in which a chemical liquid is placed, the storage chamber injects the chemical liquid into the storage chamber. It has a first hole and a second hole that discharges air from the storage chamber, and injects the chemical liquid by pushing out and discharging the air in the storage chamber in the operation of injecting the chemical liquid into the storage chamber. And air can be discharged at the same time.

The invention according to claim 4 is the chemical container with a hollow needle according to claim 3 or the container with the chemical liquid with a hollow needle in which the chemical liquid is put therein, and when the first hole is on the bottom surface of the storage chamber, The second hole is the communicating hole of the needle, and when the second hole is other than the bottom surface of the storage chamber, it is an injection port provided in the storage chamber, or a chamber wall other than the bottom surface of the storage chamber is used. In addition, the insertion of the insertion needle for loading the chemical solution does not cause the tear to spread from the needle hole, and after the needle is removed, the hole can be shrunk and the hole can be closed. It is a communication hole or a hole that penetrates a chamber wall other than the bottom surface.

The invention according to claim 5 is the body fluid collection container with a hollow needle according to claim 1 or 2,
When the chamber wall surface that is the flexible stretchable part of the storage chamber is on the upper surface opposite to the bottom surface,
By pressing the periphery of the storage chamber away from the needle or by removing the stopper that prevents the storage chamber from being restored from the contracted state, the flexible elastic part is in a concave state and a convex state by a restoring elasticity. When the chamber wall surface that is the flexible expansion / contraction part of the storage chamber is on the side surface rising from the bottom surface, the bellows-shaped surface extends to expand the volume of the storage chamber. Is characterized in that it expands and collects body fluids.

The invention according to claim 6 is the drug container with a hollow needle according to any one of claims 1 to 5, or a container with a drug solution with a hollow needle or a body fluid collection container with a hollow needle in which a drug solution is put therein. By providing a concave / convex reversing plate on the bottom surface of the storage chamber, the concave / convex reversing plate is bent upward when the concave / convex reversing plate is convex upward. When the needle is accommodated and does not protrude outward from the lower surface of the substrate portion, and the concave / convex reversing plate is convex downward, the dent is eliminated and the needle is outward from the lower surface of the substrate portion. Or when the substrate portion supporting the storage chamber is inverted, and the substrate portion is convex upward, the recess is formed by bending the substrate portion. A needle is accommodated and protrudes outside the lowermost end of the substrate portion. , When the substrate portion has a convex state under the recess is eliminated, the needle is characterized in that to exit outward from the lowermost end of the substrate portion.

The invention according to claim 7 is the drug container with a hollow needle according to any one of claims 1 to 6, or a container with a drug solution with a hollow needle or a body fluid collection container with a hollow needle in which a drug solution is added. It has a protrusion storage recess that is a recess for storing the protrusion of the counterpart needle when a plurality of the needles are stacked on the upper surface of the storage chamber opposite to the needle. To do.

The invention according to claim 8 is an integrated carrier, wherein the drug solution with a hollow needle according to any one of claims 1 to 7 is formed on a sheet that can be folded or wound for transportation and storage. A plurality of containers, or a container containing a chemical solution with a hollow needle or a body fluid collecting container with a hollow needle in which a chemical solution is put in the container, is mounted.

According to a ninth aspect of the present invention, in the integrated carrier according to the eighth aspect of the present invention, the placement and mounting on the sheet is made by alternately arranging the arranged locations and the non-placed locations.

The invention according to claim 10 is the integrated carrier according to claim 8 or claim 9,
In order to distinguish each of the hollow needle-attached body fluid collection containers, the hollow needle-attached body fluid collection container or an arrangement mounting location on the integrated carrier is provided with an identification code.

The invention described in claim 11 is an integrated carrier assembly, and is housed in a reel for winding up the integrated carrier according to claim 8, claim 9, or claim 10 or a box-shaped container for stacking vertically. It is characterized by that.

The invention according to claim 12 is the collection carrier assembly according to claim 11, wherein the collection carrier is used for drawing the collection carrier from the reel or for drawing the collection carrier from the lower side of the box-shaped container. It is characterized by having.

The invention according to claim 13 is a continuous injection device or a continuous body fluid collecting device, which is equipped with an operation unit operated by a practitioner for injection or body fluid collection, and the integrated carrier assembly, from which the integrated carrier is mounted. For the operation of the practitioner transmitted from the operation unit to the transport unit for transporting the drug and the liquid container with a hollow needle on the integrated carrier or the container with the liquid medicine with a hollow needle or the body fluid collecting container with the hollow needle 13. An integrated carrier assembly according to claim 11 or 12, characterized by comprising a pressing tool for applying a corresponding pressing pressure.

The invention according to claim 14 is the method for producing the integrated carrier according to claim 8, claim 9, or claim 10, comprising a container before the chemical solution filling of the chemical solution container with the hollow needle on the integrated carrier. Then, the chemical solution is filled, or the container with the hollow needle-filled chemical solution filled with the chemical solution is mounted on the integrated carrier.

Since it is configured as described above, the drug container with a hollow needle according to the present invention or a container with a drug solution with a hollow needle containing a drug solution, a body fluid collecting container with a hollow needle, an integrated carrier equipped with a plurality of these containers, an integrated carrier The assembly can be small and thin, can be realized at low cost, can overcome the inconvenience of air bleeding and handling of conventional containers, and can be integrated here, so it can be disposable, such as vaccination and testing of body fluids such as blood It is possible to improve convenience by using it for group treatment.

It is a figure which shows one embodiment of the chemical | medical solution container with a hollow needle | hook of this invention, the container containing a chemical | medical solution with a hollow needle which put the chemical | medical solution in this, and the bodily fluid collection container with a hollow needle. It is a figure which shows one embodiment of the integration | stacking carrier which mounts the chemical | medical solution container with a hollow needle | hook of this invention, the container containing a chemical | medical solution with a hollow needle which put the chemical | medical solution in this, and the body fluid collection container with a hollow needle. It is a figure which shows one embodiment of the integration carrier aggregate | assembly which mounts the integration carrier of this invention. It is a figure which shows another one embodiment of the chemical | medical solution container with a hollow needle | hook of this invention, the container containing the chemical | medical solution with a hollow needle which put the chemical | medical solution in this, and the body fluid collection container with a hollow needle. It is a figure which shows one Embodiment of the continuous injection apparatus or continuous body fluid collection apparatus using the accumulation | aggregation | set of carrier aggregates by this invention. It is a figure which shows another one embodiment of the continuous injection apparatus or continuous body fluid collection apparatus using the accumulation | aggregation | set of carrier aggregates by this invention. It is a figure which shows one embodiment of the transmission part which rotates a feed wheel to one direction by the repetitive up-and-down movement of a drive bar. An example of means for realizing a container with a chemical solution with a hollow needle by filling a chemical solution into the container will be described. It is a figure which shows one embodiment which mounted the chemical | medical solution container with a hollow needle which filled the chemical | medical solution, and the body fluid collection container with the hollow needle | hook before collection | collecting body fluid on the integration | stacking carrier. It is a figure which shows one embodiment which completes a container with a hollow needle, after putting a chemical | medical solution in the container with a chemical liquid with a hollow needle | hook of this invention. It is a figure which shows one embodiment which comprises the container with a hollow needle | hook of this invention on an integration | stacking carrier. It is a figure which shows one embodiment which comprises the container with a hollow needle | hook of this invention on an integration | stacking carrier. 13-A is a conventional disposable injection device, and 13-B is a view of a fine hollow needle. It is a figure of the conventional injection device. It is a figure of another conventional injection device.

The chemical solution container with a hollow needle of the present invention or a container with a chemical solution with a hollow needle in which a chemical solution is put therein, and a body fluid collection container with a hollow needle are equipped with a needle having a hollow communication hole in which a chemical solution is stored or a body fluid is stored. The bottom surface of the storage chamber has a rigid substrate portion with a needle, and the storage chamber is pressed or pulled in the same direction as the direction in which the needle is inserted and removed on the chamber wall other than the bottom surface. A flexible expansion / contraction section for expanding and contracting according to pressure, an integrated carrier in which the flexible expansion / contraction section is integrated, an aggregate thereof, an injection or a leaf using these, and a body fluid collecting device. This will be described below with reference to the drawings.

FIG. 1 is a view showing an embodiment of a drug solution container with a hollow needle of the present invention, a container with a drug solution with a hollow needle in which a drug solution is put, and a body fluid collecting container with a hollow needle. 1-A and 1-C show a perspective view at the top and a cross-sectional view at the bottom. In 1-A,
The bottom surface of the storage chamber 102, which is a space for storing the chemical solution 101, is a rigid substrate portion 106 with a needle 104 having a hollow communication hole 103 for insertion into the body, and a communication hole is formed in the storage chamber 102 from the tip of the needle. 103 are connected. The drug solution 101 can be injected into the body outside the needle 104 from the storage chamber 102 through the communication hole 103, or the body fluid can be collected in the storage chamber 102 through the communication hole 103. A chamber wall other than the bottom surface forming the storage chamber 102 (the cross section of the storage chamber is not necessarily rectangular, but a rectangular upper surface or / and a side surface), in which case the upper surface is in the same direction as the direction in which the needle 104 is inserted. In order to expand and contract the storage chamber 102, a flexible expansion / contraction section 105 that moves in accordance with a pressing pressure or a pulling pressure is provided. For this reason, the storage chamber 102 can be easily expanded and contracted in accordance with the pressing pressure or pulling pressure of a finger or the like, and body fluid can be collected or injected into the storage chamber 102 from the storage chamber 102. 1-A shows a container in which a chemical solution is contained and having a flexible stretchable part 105 on the upper surface of the storage chamber 102. Conveniently, a needle cover 107 covering the needle 104 is provided. The outer surface covered with the needle cover 107 should be flat.
A closed space surrounded by the flexible stretchable portion 105 and the substrate portion 106 is a storage chamber 102.
Since the bottom of the storage chamber 102, which is a sealed space, is a simple configuration in which the substrate portion with a needle and the top or side other than the bottom of the storage chamber 102 are the flexible expansion and contraction portion 105, all the disadvantages of the conventional product are all. Avoided. If the air is removed once in the manufacturing process for filling the storage chamber 102 with the chemical solution 101, there is no fear that air will enter thereafter. Further, since there is no need to break the storage chamber 102 or the impact of ejecting the needle tip, there is no variation in the pressing force during needle insertion or chemical injection, and the injection is performed smoothly. Furthermore, since the configuration is extremely simple, the manufacturing man-hours, materials, and other costs are extremely low. Furthermore, it can be a disposable one with minimal environmental impact.

The difference between 1-A and 1-C is that the flexible stretchable part 105 is on the top surface in the former and the side surface in the latter. When it is on the top surface, it has a hemispherical shape or an arc shape. In some cases, it has a bellows shape. In the case of 1-C as well, it is convenient to provide a needle cover 107 that covers the needle 104. The outer surface covered with the needle cover 107 should be flat.
1-B shows an example having a plurality of needles, but is not limited to this figure and can be applied to all examples.
1-D shows a case in which the flexible expansion / contraction portion 105 on the side surface of the example of 1-C is long, and accordingly, the storage chamber 102 is vertically long and can accommodate a large amount of chemical liquid or body fluid to be stored.

1-E and 1-F are shown in cross-sectional views. A chemical solution container with a hollow needle or a chemical solution container with a hollow needle in which a chemical solution is added thereto by slightly changing the chemical solution container with a hollow needle indicated by 1-A or a container with a chemical solution with a hollow needle in which a chemical solution is added. Is shown. 1-E shows a state before collecting body fluid, and 1-F shows a state after collecting body fluid. When used as a hollow needle chemical solution container or a hollow needle containing chemical solution container, the flexible telescopic part 105 does not need to return after being pushed by the pressing force and the injection is finished, rather, Since it is better not to return, restoring elasticity is not necessarily required. However, when used as a body fluid collection container with a hollow needle, the flexible telescopic part 105 is convex under 1-E and the storage chamber 102 is crushed. The storage chamber 102 must be in a state of being convex above 1-F. for that reason,
The flexible stretchable part 105 needs to be reversed by restoring elasticity, for example, by inserting a body fluid collection container with a hollow needle into the skin and inserting the container into the skin and pushing around. Therefore, it is convenient that the flexible elastic part 105 has a restoring elastic part 105B having restoring elasticity. This can be achieved, for example, by providing the flexible stretchable portion 105 with a characteristic that reverses between two states of a concave state and a convex state by pressing force. A leaf spring that changes between two states in which the unevenness is reversed can also be used. Further, before use, there is a holding stopper that prevents restoration when the storage chamber 102 is contracted. During use, the storage chamber 102 can be removed by removing the stopper so that the flexible elastic portion 105B such as a spring can be restored. Enlarging can substantially produce a change between the two states.
Body fluid collection container with hollow needle. Like 1-E and 1-F, it is not limited to the case where the flexible stretchable portion 105 is on the upper surface of the storage chamber 102. The same applies to the case of the side surface such as 1-C. The flexible stretchable portion 105 that has shrunk before use may be extended during use to increase the volume of the storage chamber 102. In particular, it is better for the thin 1-C length to have a restoring resilience, but for a long one like 1-D. Since the volume of the storage chamber 102 can be increased by extending it with a doctor's hand, it is not necessarily required to have the resilience.
The flexible stretchable part 105 is conveniently a soft film made of a resin such as polycarbonate, polystyrene, polyolefin, polyethylene terephthalate, polyethylene, polypropylene, nylon, vinyl chloride, or the like. Among these, those having restoration elasticity are natural rubber film, synthetic rubber film, resin film used in the range of elastic force that does not lead to plastic deformation, restoration leaf spring, or resin reinforced with leaf springs with inverted irregularities. A membrane or the like can be used.

FIG. 2 is a diagram showing an embodiment of an integrated carrier equipped with a plurality of hollow liquid drug containers with a hollow needle, a liquid container with a hollow needle containing a liquid medicine, and a body fluid collection container with a hollow needle according to the present invention.
As shown in FIG. 1 or shown in FIG. 4 after that, a hollow liquid chemical container with a hollow needle or a liquid container with a hollow needle containing a chemical liquid, a plurality of body fluid collection containers with a hollow needle are made of thin paper, resin sheet, etc. This is an extremely convenient integration mode for transportation and storage until use, further storage in use, and continuous feeding when used with an injection device.
In 2-A, a medicine container with hollow needles or a container with a medicine solution with hollow needles or a body fluid collecting container with hollow needles (hereinafter referred to as a container with hollow needles 202) in a row is placed on the integrated carrier 201. Arranged at moderate intervals. A perforation may be provided on the accumulation carrier 201 between the hollow needle-equipped containers 202 so that it can be easily separated. 2-B is an example in which a conveying gear slot 203 for feeding with a mechanical gear is provided on the accumulation carrier 201 on both sides of the hollow needle-equipped container 202. In 2-C, instead of the conveying gear slot 203, an example is provided in which conveying teeth 204 are provided in which the peaks and valleys are alternately and continuously (ragged). 2-D is an example in which a plurality of hollow needle-equipped containers 202 (eight in this example) are arranged on one carrier sheet.
Such carrier sheets are stacked vertically. Each sheet can be removed here.
In 2-E, every other hollow needle-equipped container 202 is disposed on the carrier sheet, and no single hollow needle-equipped container 202 is disposed between the individual hollow needle-equipped containers 202. There is an arrangement location 205. In this way, when folded as shown in the figure, the hollow needle-equipped containers 202 can all be stacked vertically in the same direction, and the stacked body is pulled out from the opening under the box in a box. In this case, it can be taken out smoothly and is very convenient. Otherwise, if the orientation is different, it is necessary to change the orientation and it cannot be taken out smoothly.
In all the examples, at the time of use, the individual container 202 with the hollow needle can be separated and used before use or after use (after application). As a material of the integrated carrier 201, a film such as a resin such as polycarbonate, polystyrene, polyolefin, polyethylene terephthalate, polyethylene, polypropylene, nylon, or vinyl chloride can be used.
In addition, in the body fluid collection container with a hollow needle, it is convenient to distinguish the body fluid collection container with a hollow needle if it is provided with an identification code corresponding to the arrangement mounting location on the integrated carrier.

FIG. 3 is a diagram showing an embodiment of an integrated carrier assembly on which the integrated carrier of the present invention is mounted.
3A is an integrated carrier assembly 300 using a reel 301 that winds and stores the integrated carriers shown in 2-A, 2-B, 2-C, and 2-E, and for pulling out the integrated carrier 302. It is convenient to have a pull-out opening 303. The reel 301 has a structure capable of winding up the integrated carrier 302 between two disk-shaped side walls 304.
In 3-B, the box-type integrated carrier assembly 300 for storing the integrated carrier shown in 2-D can be taken out by opening the outlet 303 or the upper lid of the box.
In 3-C, a vertically long box-shaped integrated carrier assembly 300 that accommodates the stacked carriers shown in 2-A, 2-B, 2-C, 2-E in a vertically stacked manner, In -B and 2-C, the upper lid can be opened and taken out, and in the case of 2-E, the upper lid can be opened and taken out, or pulled out from the outlet 303 provided below. By using these integrated carrier assemblies 300, it is possible to separate the individual hollow needle-equipped containers 202 drawn by the doctor who uses them each time they are used without using a special machine and to use them easily. can do.

Returning to the description of the chemical container with a hollow needle, the container with a chemical liquid with a hollow needle, and the body fluid collecting container with a hollow needle, as in FIG.
FIG. 4 is a diagram showing another embodiment of the chemical solution container with a hollow needle of the present invention, a container with a chemical solution with a hollow needle in which a chemical solution is put, and a body fluid collection container with a hollow needle. When the integrated carrier and the integrated carrier assembly described in FIG. 2 and FIG. 3 are configured by stacking or winding the chemical solution container with the hollow needle, the chemical solution container with the hollow needle in which the chemical solution is put therein, or the body fluid collection container with the hollow needle. 1 can be used as well as the hollow needle chemical solution container, the hollow solution medicinal solution container containing the chemical solution, and the hollow needle body fluid collection container. A liquid container with a hollow needle having means for preventing the needle from hitting another container and damaging the storage chamber 102, and means for preventing the protrusion of the needle from getting in the way when it is pulled out. A container with a chemical solution with a hollow needle and a body fluid collection container with a hollow needle in which the chemical solution is placed will be described.
In 4-A to 4-C, it is convenient when a plurality of liquid medicine containers with a hollow needle, a liquid medicine container with a hollow needle in which a liquid medicine is put therein, or a body fluid collection container with a hollow needle are stacked and accommodated without a needle cover. An example is shown. In the figure, the projection housing recess 108 for housing the projection of the mating needle 104 when overlapped is provided on the upper surface opposite to the side where the own needle is present.
In 4-A and 4-C, the protrusion housing recess 108 is limited to the place where the needle 104 is located, and in this figure, it is in the middle position. The difference between 4-A and 4-C is that the flexible stretchable part 105 is on the top surface in the former and the side surface in the latter. When it is on the top surface, it has a hemispherical shape or an arc shape. In some cases, it has a bellows shape.
In 4-B, the protrusion housing recess 108 is formed so as to penetrate in one direction toward the side surface including the place where the needle 104 is present. In this way, the protrusion of the needle 104 can be pulled out along the passage of the protrusion receiving recess 108 that passes therethrough, which is advantageous because it can be easily pulled out when stacked.

4-D to 4-G are shown only in cross-sectional views. In 4-D and 4-E, the state before injection and during injection is shown. Similarly, 4-F and 4-G indicate states before and during injection. These can also be used for collecting body fluids, with 4-E and 4-G before collection and 4-D and 4-F after collection.
In 4-D, the concavo-convex reversing plate 109 on which the concavo-convex portion is inverted by the pressing pressure is on the lower surface of the substrate portion 106, and when there is no pressing pressure before injection, the needle 104 is convex upward. Enters the recess 110 and does not protrude outside the lower surface of the substrate portion 106.
In 4-E, when it is applied to the injection site of the body and pressed with a finger or the like, the unevenness of the uneven reversing plate 109 is inverted and convex downward, and the needle 104 is located outside the lower surface of the substrate portion 106, and injection is performed. The drug solution 101 is injected into the site. Naturally, the storage chamber 102 is contracted in the direction of the needle, and shows a state in which the drug solution 101 remains slightly here.
The difference between 4-F and 4-D will be described. In 4-D, the concave / convex reversing plate 109 with the needle 104 is reversed, whereas in 4-F, the concave / convex portions of the substrate 106 supporting the needle 104 and the storage chamber 102 are reversed. In 4-F, before the injection, the substrate portion 106 is convex upward and the needle 104 is in the recess 110 created by the substrate portion 106. 4G shows a state in which the needle is protruded by bending the substrate portion 106 to a flat position or a convex position downward during injection.
For both 4-E and 4-G, the needle 104 is housed in the recess 110 by pulling out the post-injection and pressing the periphery of the substrate 106 downward to reverse the uneven warp. It is also possible.
Note that the concave / convex reversing mechanism of the concave / convex reversing plate 109 can be used as described in Japanese Patent Laid-Open No. 6-203729. As a material of the thin plate 109, resins such as polycarbonate, polystyrene, polyolefin, polyethylene terephthalate, polyethylene, polypropylene, nylon, and vinyl chloride can be used.

FIG. 5 is a view showing an embodiment of a continuous injection device or a continuous body fluid collecting device using an integrated carrier assembly according to the present invention. Here, it is a continuous injection device or a continuous body fluid collecting device (hereinafter referred to as a hand-held continuous injection device) that is operated by a doctor.
In 5-A, the hand-held continuous injection device 500 includes a grip portion 510 for holding by hand, a body portion 520 connected thereto, a treatment portion 530 attached to the tip thereof, and an integrated carrier assembly 300 attached thereto. ing. In the treatment section 530, the accumulation carrier is conveyed from the accumulation carrier assembly 300 containing the accumulation carrier, supplied with the container 202 with the hollow needle, and pressed to perform the treatment (injection or body fluid collection). The carrier is wound up for each treatment.

First, 5-C which expanded and showed the treatment part 530 is demonstrated. A pressing tool 532 for pressing and pressing the hollow needle-equipped container 202 is provided inside the treatment portion housing 531. The treatment portion bottom surface 533 which is the bottom surface of the treatment portion casing 531 is open, and the body is used by being applied to the treatment portion. The integrated carrier 534 moves so as to crawl on this bottom surface. In this figure, the integrated carrier 534 enters from the left side, and is pressed by the pressing tool 532 on the treatment unit bottom surface 533, and after the treatment is performed, it exits from the right side. Go. The movement of the movement of the accumulation carrier 534 is performed by a rotating feed gear 535. Here, six gears are shown, but the number is not limited to this. In addition to the gears, the same operation is possible with a friction feed wheel such as a belt-driven feed wheel. Naturally, on the side of the integrated carrier 534, there is naturally a feed mechanism (2-B carrying gear slot 203, 2-C carrying tooth 204, etc.) corresponding to these feed gears and feed wheels. It is.
In this example, the pressing tool 532 is moved up and down as a column 536 is guided to a cylinder 537 that guides the column 536. The cylinder 537 is connected and fixed to the treatment portion housing 531.
When moved downward, the treatment is performed by pressing the hollow needle-equipped container 202 on the accumulation carrier 534. The operation of the pressing pressure will be described. A driving wire 539 accommodated in the driving guide tube 538 is connected to the tip of the cylinder 536 opposite to the tip on the side to be pressed, and the other tip of the driving wire 539 is a trigger on the body 520. Since it is connected to 540, when the trigger 540 is pulled, the drive wire 539 is pushed, and the column 536 descends to press the container 202 with the hollow needle. The drive guide tube 538 is connected and fixed to the body portion 520.
When the trigger 540 is released, the trigger 540 is returned by a spring (not shown), and the cylinder rises. Although the feeding operation is also performed by this triggering operation, the feeding operation is the same as that performed in FIG. 6 and will be described later with reference to FIGS. 6 and 7.

Of the integrated carrier aggregate 300, the one that stores the integrated carrier and supplies it to the treatment unit 530 is an example of using 5-A in 5-A, but in 5-B, , 3-C. The integrated carrier assembly 300 has the advantage that it can be extended upward and does not interfere with the treatment.
The means for realizing the device such as a hand-held continuous injection can take many different forms other than those described in this example.

FIG. 6 is a view showing another embodiment of the continuous injection device or the continuous body fluid collecting device using the integrated carrier assembly according to the present invention. Here, a doctor or the like does not operate by hand, but is a stationary continuous injection device or a continuous body fluid collecting device (hereinafter referred to as a stationary continuous injection device).
In the case 600, almost the same means as the apparatus such as the hand-held continuous injection shown in FIG. The integrated carrier aggregate 300 (here, 3-A reel shape) is attached to the left and right, and the integrated carrier 534 is sent so as to move from the left to the right. A pressing tool 532 is provided, and a column 536 is guided to a cylinder 537 that guides the column 536 so as to move up and down. The cylinder 537 is connected and fixed to the housing 600. A driving bar 539B having the same function as the driving wire 539 is connected to the side opposite to the side to be pressed of the cylinder 536, and transmits the operation of the trigger 540 or the handle. The trigger 540 or the handle is returned by the restoring force of the spring 541. The integrated carrier 534 is transported through the transporting gear slot 203 and the transporting teeth 204, and is provided with a feed wheel 545 such as a transporting gear or a friction wheel that is coupled so as to be transportable. Then, the feed wheel 545 further drives the rotating shaft 547 that moves the accumulation carrier from the accumulation carrier assembly 300 by the first transmission wire or the belt 546. A driving force that causes the feed wheel 545 to move is transmitted by a second transmission wire or a belt 544 that connects this and the reciprocating partial rotary wheel 543. Further, since the arm connecting piece 542 attached to the reciprocating partial rotating wheel 543 is rotatably connected to the drive bar 539B, the rotation feed is achieved when the drive bar 539B moves in the up and down direction, particularly when it recovers upward. The In order for the driving bar 539B to repeatedly move up and down, the feed carrier 545 needs to have a rotating portion having a ratchet rotating mechanism that moves only in one direction in order that the accumulated carrier is not reciprocated but sent in one direction. This is illustrated in FIG.
Below the integrated carrier assembly 300 just below the pressing tool 532 is a body pedestal 548 for inserting a body such as a patient's arm, which is further supported by a lifter 549 that moves the body pedestal 548 up and down. It has been. Thereby, it can assist that a body, such as an arm, adheres to an accumulation carrier.

FIG. 7 is a diagram showing an embodiment of a transmission unit that rotates the feed wheel in one direction by repeated vertical movement of the drive bar. There is an arm connecting piece 542 between the drive bar 539B and the transmission reciprocating partial rotating wheel 543, which can rotate and expand and contract. Further, the transmission reciprocating partial rotating wheel 543 drives the feed wheel 545 by a transmission tool such as a belt. However, the second feed wheel 545B attached to this reciprocating operation of the feed wheel 545 is unidirectional. Has a ratchet combination that can only be rotated.

In the above description, the drive transmission from the trigger 540 is performed only by mechanical means, but it can also be electrically driven by electric means. For example, it is natural that the motor can be driven directly without using a belt or the like. Operation switches or operation buttons are used instead of triggers. The trigger 540 and the operation switches or operation buttons are means for operations performed by the practitioner and are described as operation units.

The following shows the means for filling the chemical solution into the container and mounting it on the integrated carrier.
FIG. 8 shows an embodiment of means for realizing a container with a chemical solution with a hollow needle by filling the chemical solution into the container.
8-A is a storage chamber for a completed container 800 with a hollow needle (in this example, a 4-B container with a lid on the needle side. Of course, another container may be used). A medical solution is injected using a state in which the flexible stretchable portion 105 of 102 is pressed in advance and the storage chamber 102 has been air-bleeded. Here, a large syringe-like injector 801 is shown for injecting, but industrially, a continuous operation apparatus in which the amount of injection can be easily controlled is used. By the injection, the chemical solution enters the storage chamber 102 and swells. The bottom two containers are filled with chemicals on the left side, and the right side shows a state where air is not sufficiently vented and a little air remains. Therefore, it is possible to prevent air from entering the patient. After injection,
A closing lid 802 is attached to close the injection hole. The closing lid 802 may be closed by pressure bonding or the like in addition to pasting, and other forms are possible. In order to perform complete air bleeding, a part of the flexible stretchable portion 105 may be provided with an air bleeding hole that will be closed later.

8B shows an injection means that enables air bleeding while injecting with the injector 801.
The injection needle or injection port 801B of the injector is an example in which another penetrating hollow needle 803 is provided for air bleeding in addition to the needle for injecting a chemical solution, and the other is the same as 8-A. Since the other end of the penetrating hollow needle 803 is an air vent needle open end 804 that is open to the air, as the medicinal solution is filled from the medicinal solution injecting needle, the air is pushed out and the penetrating hollow needle 803 is opened. The needle 803 is discharged out of the storage chamber 102. When the chemical solution comes out from the air release needle open end 804, the air is completely removed. After the injection, a closing lid 802 is provided. The flexible stretchable part 105 for inserting and removing the needle is not of a property that the damaged part spreads out by the needle, but after the needle is pulled out, it is convenient that the mouth of the damaged part is contractible so that the chemical solution does not flow out. However, it is possible to perform the closing lid 802 in a situation where the chemical solution does not flow out. The mouth of such a damaged part needs to have a plastic restoring elasticity, for example, the material needs to have plastic restoring elasticity.For example, a small hole is opened by inserting a needle like rubber. The property is that the hole is closed or very small.
Even when there is no plastic restoring elasticity, if a liquid injection port and an air vent hole that can be closed after the liquid injection is provided in a part of the flexible stretchable part 105, the lid 802 is closed after the injection, or Means such as crimping the chemical solution inlet and the air vent hole are possible.
May be.

8C shows an example in which a chemical solution is injected by a syringe 801 from a chemical solution injection hole 805 provided on the bottom surface of the hollow needle-equipped container 800 on the side where the needle is provided (the side opposite to the flexible stretchable portion 105 side). When the chemical solution enters the storage chamber 102 by the injection, air is discharged from the hole of the needle 104, so that no special air discharging means is required. After the chemical solution is injected, the chemical solution injection hole 805 is closed and closed with the lid 802. A needle cover 806 that further closes and covers the needle 104 is shown on the lower right side.

8-D shows an example in which the chemical solution is injected by the injector 801 from the flexible stretchable portion 105 side. When the chemical solution enters the storage chamber 102 by the injection, air is discharged from the hole of the needle 104, so that no special air discharging means is required. After the chemical solution is injected, the chemical solution injection hole 805 is closed and closed with the lid 802. A needle cover 806 that further closes and covers the needle 104 is shown on the lower right side.

In addition, although chemical | medical solution injection | pouring and air bleeding were described in the example of the chemical | medical solution container with a hollow needle of the form of 4-B of FIG. 4, the chemical | medical solution container with a hollow needle which put the chemical | medical solution in this, and the bodily fluid collection container with a hollow needle. The medicinal solution container with a hollow needle according to the present invention or a container with a medicinal solution with a hollow needle in which a medicinal solution is put, and a body fluid collecting container with a hollow needle are the same in all the forms shown in FIGS. Since these containers have a simple configuration, it is easily satisfied that the chemical injection and the air venting are achieved at the same time by the single chemical liquid injection operation from the needle side or the flexible expansion / contraction part side. . Of course, there is no worry of air coming in after that. The problems and troublesomeness of the conventional product shown in FIG. 15 are overcome without any fear here.

Before filling the chemical solution from 8-A to 8-C, first, as shown in 8-E, the hollow needle-equipped container 800 is realized. In the container 800 with a hollow needle, the hollow needle is fixed to the bottom surface of the storage chamber 102, and the surface other than the bottom surface has a portion that becomes the flexible stretchable portion 105. Therefore, as in 8-E, for example, first, It is also possible to make the entire storage chamber 102 of a flexible stretchable material and to join a needle substrate 807 having a hollow needle directly to the bottom portion via a hard plate or directly. As in all examples, there can be multiple needles.

FIG. 9 is a view showing an embodiment in which a container with a chemical solution with a hollow needle that has been filled with a chemical solution and a body fluid collection container with a hollow needle before collecting body fluid (container 202 with a hollow needle) are mounted on an integrated carrier.
In the figure, the example is shown by 2-C in FIG. 2 and 4B in FIG. In 9-A, the container 202 with hollow needles is fixed with the needle side down from the top of the integrated carrier. Therefore, a passage hole 901 such as a needle is opened in the accumulation carrier at a position where the container 202 with the hollow needle is placed so that the needle can be pulled out to the back side of the accumulation carrier. In 9-B, the hollow needle-equipped container 202 is fixed with the flexible stretchable portion 105 facing upward from under the stacking carrier. In this case, since the needle side faces outward, there is no need for a passing hole 901 such as a needle in the integrated carrier.

8 and FIG. 9 are examples in which the chemical solution is put in after the container 800 with a hollow needle is completed, but FIG. 10 shows the chemical solution container with the hollow needle of the present invention or the chemical solution with a hollow needle in which the chemical solution is put therein. It is a figure which shows one embodiment which completes a container with a hollow needle after putting a chemical | medical solution in a container. Although shown by the example of the container with 4-B hollow needle of FIG. 4, it is the same also with another container. In 10-A, the storage chamber 102 having the opening 1001 on the bottom surface side with the needle is placed with the flexible expansion / contraction portion 105 side down, and the storage chamber 102 is filled with the chemical solution 1002 from the opening 1001. It is also possible to fix the needle substrate 807 with needles after filling.
On the other hand, in 10-B, the liquid 1002 is filled into a container with a hollow needle already attached with a needle on the side of the flexible stretchable portion 105 that is not yet attached and opened. Thereafter, the side with the flexible stretchable part 105 is fixed. Both are shown in a perspective sectional view.

11 and 12 are views showing an embodiment in which the hollow needle-equipped container 202 is configured on the accumulation carrier. FIG. 11 shows a case where the storage chamber 102 having the opening 1001 on the bottom surface side where the needles are first placed on the integrated carrier is arranged first with the flexible stretchable part 105 side down. In FIG. This is a case where a container with a hollow needle attached to which a side on the flexible stretchable part 105 side is not attached yet and is opened first is arranged.
First, in FIG. 11, when the storage chamber 102 is arranged with the flexible stretchable portion 105 side down, it is arranged from above the integrated carrier as in 111-A and from below as in 11-B. There are two ways to do this. In the former, the integrated carrier 201 does not need a through hole at the position where the hollow needle container 202 is arranged, but in the latter, the integrated carrier needs a through hole 1101.
Both 11-A and 11-B show the container before placement on the left side of the arrow and the container after placement on the right side.
In 11-A, the storage chamber 102 is disposed on the upper side of the integrated carrier 201, and in 11-B, it is disposed on the lower side. In 11-C, the needle substrate 807 with the needle is bonded to both cases. Thereafter, in 11-D, a needle cover 1102 that covers the needle is placed. This cover is removed when in use. 11-E shows a state where the cover of the needle cover 1102 is completed. Here, the needle cover 1102 may be in the form of a continuous sheet, or may have a shape in which a continuous teacup is turned down like 11-H (there is a dent in which the needle fits like a teacup). Moreover, it is not connected and you may become individual for every needle | hook here. In addition, the example of the shape of the storage chamber 102 arrange | positioned is expanded and shown to 11-F. Although the example shown in 4-B of FIG. 4 is taken as an example, the same applies to the other examples shown in FIG. 1-G shows an example in which the needle substrate 807 with needles is enlarged.

In FIG. 12, in 12-A, a container with a needle that is not yet attached to the flexible stretchable portion 105 side is first arranged from the lower side of the accumulation carrier 201. The integrated carrier 201 needs an opening hole 901B to cover the storage chamber lid 102B from above. 12-B shows a state after arrangement. In 12-C, a needle cover 1102 that covers the needle is put on. 12-D shows the subsequent state. 12-E is covered and joined with a storage chamber lid 102B having a flexible stretchable portion 105 from the upper side of the integrated carrier 201. The result is a 12-F state.

11 and 12, the chemical solution can be filled before the needle substrate 807 or the storage chamber lid 102 </ b> B is covered, and the chemical solution is filled after the empty needle container 202 is completed on the integrated carrier 201. Is also possible. Of course, as shown in FIGS. 8, 9, and 10, a completed hollow needle container 202 filled with a chemical solution can be disposed on the integrated carrier. Many variations are possible.

The drug container with a hollow needle shown in FIGS. 1 and 4, a container with a drug solution with a hollow needle in which a drug solution is put, and a body fluid collection container with a hollow needle can be attached to the body and used.
The common contents of the words used in the above explanation are summarized below.
The hollow needle is a needle having a hollow hole penetrating inward in the longitudinal direction from the tip of the needle to the base, and the injection needle and the blood collection needle are hollow needles. Conventionally, long metal needles have been used, but in recent years, many proposals for fine needles, for example, as shown in 13-B of FIG. 13 (Japanese Patent Laid-Open No. 2008-154849) have come to be seen. These can also be used. In addition to this example, JP 2011-230396, JP 2004-524172, JP 2006-204540, and the like have detailed descriptions on dimensions and materials. In the former two, the features of micro hollow needles are 50 μm to 1000 μm in length, especially 50 μm to 150 μm, outer diameter 20 μm to 100 μm, inner diameter 5 μm to 50 μm, and materials such as silicon, stainless steel, especially these types are used. In the later Japanese Patent Application Laid-Open No. 2006-204540, microneedles using hair as a material have been proposed. In general, since the needle itself needs to have a hardness that does not bend and does not bend, in many cases, the needle and the substrate that supports the needle are formed simultaneously to form the needle substrate. Otherwise, it is difficult and troublesome to join the needle hole and the hole of the substrate together. Further, in the present application, it is not necessary to be a microneedle, but a microneedle is preferable for accumulation. In consideration of disposable, a resin needle is preferable.

Depending on the amount of chemicals and body fluids to be stored in the storage chamber, it is convenient to take up an area as much as possible and to form it thinly. The proposal according to the present invention is convenient when applied mainly to a small amount of chemicals or body fluids. In that case, the thickness of the storage chamber is preferably 3 mm or less. When the amount of the chemical solution or body fluid is large, it is not suitable for stacking and accumulation, but it is possible to take a form such as 1-D in FIG. As the material of the storage chamber, in consideration of disposable, resins such as polycarbonate, polystyrene, polyolefin, polyethylene terephthalate, polyethylene, polypropylene, nylon, and vinyl chloride are suitable. As the substrate portion, a hard one is suitable.
Although not particularly described, it is preferred that the chemical solution container with a hollow needle of the present invention, the container with a chemical solution with a hollow needle in which a chemical solution is put, and the body fluid collection container with a hollow needle are subjected to sterilization treatment or the like.

As described above, the drug container with a hollow needle according to the present invention or a container with a drug solution with a hollow needle containing a drug solution, a body fluid collecting container with a hollow needle, an integrated carrier equipped with a plurality of these containers, an integrated carrier assembly, and continuous injection The device and continuous body fluid collection device avoid the inconvenience of air bleeding and its handling, simplify the structure, enable compact housing and continuous use, reduce costs by reducing manufacturing man-hours and materials, Since it can be used safely and easily, the industrial applicability is extremely high.

DESCRIPTION OF SYMBOLS 101 Chemical solution 102 Storage chamber 103 Communication hole 104 Needle 105 Flexible expansion-contraction part 106 Substrate part 107 Needle cover 108 Protrusion storage recessed part 109 Concave / inverted plate 110 Recess 201 Accumulated carrier 202, 800 Hollow needle container 203 Conveying gear slot 204 Tooth 205 Non-placed portion 300 Integrated carrier assembly 301 Reel 302, 534 Integrated carrier 303 Drawer 304 Disc-shaped side wall 500 Hand-held continuous injection device 510 Hand grip 520 Body 530 Treatment portion 531 Treatment portion housing 532 Press tool 533 Treatment Bottom surface 535 Feed gear 536 Column 537 Cylinder 538 Drive guide tube 539 Drive wire 539B Drive bar 540 Trigger 541 Spring 542 Arm connection piece 543 Reciprocating partial rotary wheel 544 Second transmission wire or belt 545 Feed wheel 545B Second feed wheel 546 First One story Wire or belt 547 Rotating shaft 548 Body stand 549 Lifter 600 Housing 801 Syringe 801B Syringe or inlet 802 Closed lid 803 Penetration hollow needle 804 Air venting needle open end 805 Chemical solution injection hole 806 Needle cover 807 Needle substrate 901 Needle etc. Passage hole 901B Opening hole 1001 Opening part 1002 Chemical solution 1101 Through hole 1102 Needle cover

Claims (14)

It is a storage chamber provided with a needle having a hollow communication hole for storing a chemical solution or a body fluid, and the bottom surface of the storage chamber has a rigid substrate portion provided with the needle, The chamber wall other than the bottom surface is a flexible expansion and contraction part for collecting and storing bodily fluids or injecting medicinal liquids by extending or contracting the storage chamber according to the pressure or pressing force in the same direction as the direction in which the needle is withdrawn and pierced. A medical solution container with a hollow needle, a container with a chemical solution with a hollow needle, or a body fluid collection container with a hollow needle, in which a chemical solution is placed. The chamber wall surface, which is the flexible expansion / contraction part of the storage chamber, is a surface that moves while deforming in the direction of the pulling pressure or pressing pressure when it is on the upper surface opposite to the bottom surface, or from the bottom surface. 2. A medical solution container with a hollow needle according to claim 1, or a container with a chemical solution with a hollow needle or a hollow needle in which a chemical solution is placed therein, characterized in that when it is on a rising side surface, it is a stretchable bellows-shaped surface Body fluid collection container. The storage chamber has a first hole for injecting a chemical solution into the storage chamber and a second hole for discharging air from the storage chamber. 3. The medical solution container with a hollow needle according to claim 1 or 2, wherein the chemical solution can be injected and discharged at the same time by being pushed out and discharged. Container with chemical solution with hollow needle. When the first hole is in the bottom surface of the storage chamber, the second hole is the communication hole of the needle, and when the first hole is other than the bottom surface of the storage chamber, the inlet provided in the storage chamber Or, the chamber wall other than the bottom surface of the storage chamber is not torn from the needle hole by inserting / removing the insertion needle for loading the chemical solution, and after the needle is removed, the hole shrinks and the hole closes. 4. The medicinal solution with a hollow needle according to claim 3, wherein the second hole is the communication hole of the needle or a hole penetrating a chamber wall other than the bottom surface. A container containing a chemical solution with a hollow needle in which a chemical solution is placed in the container. When the chamber wall surface, which is the flexible expansion and contraction part of the storage chamber, is on the upper surface opposite to the bottom surface, it presses the periphery of the storage chamber away from the needle, or the storage chamber contracts By removing the stopper that prevents restoration, the flexible elastic part is inverted between two states of a concave state and a convex state by restoring elasticity, or the chamber wall surface that is the flexible elastic part of the storage chamber is 3. The hollow needle according to claim 1, wherein when it is on a side surface rising from the bottom surface, the volume of the storage chamber is expanded by collecting the bellows-like surface to collect body fluid. Body fluid collection container. By providing a concave / convex reversing plate on the bottom surface of the storage chamber, the concave / convex reversing plate is bent upward when the concave / convex reversing plate is convex upward. When the needle is accommodated and does not protrude outward from the lower surface of the substrate portion, and the concave / convex reversing plate is convex downward, the dent is eliminated and the needle is outward from the lower surface of the substrate portion. Or when the substrate portion supporting the storage chamber is inverted, and the substrate portion is convex upward, the recess is formed by bending the substrate portion. When the needle is accommodated and does not protrude outward from the lowermost end of the substrate portion, and the substrate portion protrudes downward, the dent is eliminated, and the needle is outward from the lowermost end of the substrate portion. Either one of claims 1 to 5, wherein Hollow needle with the drug solution container or a hollow needle with the drug solution container filled or hollow needle with fluid collection container which put a chemical according to One. It has a protrusion storage recess that is a recess for storing the protrusion of the counterpart needle when a plurality of the needles are stacked on the upper surface of the storage chamber opposite to the needle. A drug solution container with a hollow needle according to any one of claims 1 to 6, a container with a drug solution with a hollow needle, or a body fluid collection container with a hollow needle in which a drug solution is placed. A medical solution container with a hollow needle according to any one of claims 1 to 7, or a container with a chemical solution with a hollow needle in which a chemical solution is placed on a sheet that can be folded or rolled up for conveyance and storage Alternatively, an integrated carrier in which a plurality of body fluid collection containers with hollow needles are arranged and mounted. 9. The integrated carrier according to claim 8, wherein the placement and mounting on the sheet are alternately arranged locations and non-placed locations. 10. The body fluid collection container with a hollow needle or an arrangement mounting location on the integrated carrier is provided with an identification code to distinguish each of the body fluid collection containers with a hollow needle. Integrated carrier. An integrated carrier assembly, wherein the integrated carrier assembly is housed in a reel for winding the integrated carrier according to claim 8, claim 9, or claim 10 or a box-shaped container for stacking vertically. 12. The integrated carrier assembly according to claim 11, further comprising a take-out port for pulling out the integrated carrier from the reel or pulling out the integrated carrier from a lower side of the box-shaped container. An operation unit operated by a practitioner for injection or body fluid collection, a transport unit that carries the integrated carrier assembly and transports the integrated carrier therefrom, and a chemical solution container with a hollow needle on the integrated carrier, or a chemical solution on the container 12. A pressing tool for applying a pressing force according to the operation of the operator transmitted from the operating unit to a container with a hollow needle containing chemical solution or a body fluid collecting container with a hollow needle. Item 13. A continuous injection device or a continuous body fluid collecting device, wherein the integrated carrier assembly according to Item 12 is used. After providing the container before filling the chemical solution of the container with the hollow needle on the integrated carrier, the chemical solution is filled, or the container with the hollow needle filled with the chemical solution is filled on the integrated carrier. The method for producing an integrated carrier according to claim 8, wherein the integrated carrier is mounted on the carrier.

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