JP2013091629A - Disinfectant composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a disinfectant composition capable of preventing corrosion of a metallic member and excellent in sterilizing power.SOLUTION: The disinfectant composition includes a component (A) and a component (B). The component (A) is N,N-bis(3-aminoalkyl)alkylamine represented by general formula (I): R-N[(CH)-NH], wherein Ris a 8-18C alkyl group and n is a number of 1-4. The component (B) is one or more elements selected from the group consisting of silver, zinc, and copper. Preferably, the component (A) is N,N-bis(3-aminopropyl)alkylamine.

Description

  The present invention relates to a bactericidal composition.

The presence and proliferation of microorganisms may cause various problems and infections, and countermeasures have been demanded.
In recent years, due to the increase in hygiene orientation, various cleaning agents in the daily necessities field such as clothing cleaning agents and kitchen cleaning agents can sterilize microorganisms adhering to the object to be cleaned in addition to removing visible dirt. It has been demanded. Disinfecting components used in cleaning agents include chlorine-based disinfectants such as sodium hypochlorite, oxygen-based disinfectants such as sodium percarbonate, sodium perborate, hydrogen peroxide, didecyldimethylammonium chloride, and benzal chloride. Quaternary ammonium salts such as ruconium are known.
Oxygen-based disinfectants have low disinfecting power, and when formulated in liquid preparations, there is a problem that hydrogen peroxide is easily decomposed during storage and the dosage form is limited.
Chlorine disinfectants and quaternary ammonium salts are prone to generate rust and corrode metal members. In addition, the quaternary ammonium salt has a problem that when used in combination with an anionic surfactant, the bactericidal power is significantly reduced.

Conventionally, preparations containing bactericidal components other than oxygen-based bactericides, chlorine-based bactericides, and quaternary ammonium salts have been proposed.
For example, a disinfectant / antibacterial agent composition containing a mixture or complex of a specific water-soluble metal salt and a specific long-chain alkylamine has been proposed (for example, Patent Document 1).
Alternatively, a bactericide containing N, N-bis (3-aminopropyl) octylamine has been proposed (for example, Patent Document 2).

International Publication No. 2009/110590 Special table 2003-503321 gazette

However, the techniques of Patent Documents 1 and 2 have not yet achieved a satisfactory sterilizing power.
Then, this invention aims at the bactericidal composition which can suppress the corrosion of a metal member and is excellent in bactericidal power.

  As a result of intensive studies, the present inventors have used a specific N, N-bis (3-aminoalkyl) alkylamine and a specific metal in combination, thereby preventing metal corrosion and improving the bactericidal power. As a result, they have reached the present invention.

That is, the bactericidal composition of the present invention comprises (A) component: N, N-bis (3-aminoalkyl) alkylamine represented by the following general formula (I), and (B) component: silver, zinc, and And at least one selected from the group consisting of copper.
^{_{R 1 -N [(CH 2)}} n -NH 2] 2 ··· (I)
[In the formula (I), R ¹ represents an alkyl group having 8 to 18 carbon atoms, and n is a number of 1 to 4. ]
The component (A) is preferably N, N-bis (3-aminopropyl) alkylamine.

  According to the bactericidal composition of the present invention, the bactericidal power can be improved while suppressing the corrosion of the metal member.

(Bactericidal composition)
The bactericidal composition of the present invention comprises (A) component: N, N-bis (3-aminoalkyl) alkylamine and (B) component: one or more selected from the group consisting of silver, zinc, and copper. , Containing.
A bactericidal composition means all the compositions which have a bactericidal effect with respect to a to-be-processed object.

The dosage form of the bactericidal composition may be a liquid or a solid such as a granule, a tablet, a briquette, a sheet, or a bar, and may be applied directly to an object to be processed or diluted with water or the like. From the viewpoint of convenience in doing so, a liquid is preferred.
In the case of a liquid bactericidal composition (hereinafter sometimes referred to as a liquid bactericidal composition), it may be a one-pack type in which both the component (A) and the component (B) are mixed in a dispersion medium, A two-component type composed of a first liquid containing the component (A) and a second liquid containing the component (B) may be used.
In the case of a solid bactericidal composition (hereinafter sometimes referred to as a solid bactericidal composition), the component (A) and the component (B) may be mixed, or the component (A) and the component (B). May be prepared as separate granular materials.

The viscosity of the liquid bactericidal composition is not particularly limited and is, for example, 10 to 300 mPa · s. The viscosity of the liquid bactericidal composition indicates a value (measurement condition: rotor No. 2, rotation speed 30 rpm, viscosity after 10 rotations) measured by a B-type viscometer (manufactured by TOKIMEC).
The pH of the liquid bactericidal composition can be determined in consideration of the dosage form. The pH of the concentrated liquid bactericidal composition used as the treatment liquid diluted by being poured into water is, for example, preferably 4 to 12, more preferably 7 to 11. If it is less than the above lower limit, the pH of the treatment liquid is lowered, and the sterilizing power may be reduced. If it exceeds the upper limit, a precipitate may be generated during storage.
Further, in the case of a straight type liquid bactericidal composition used without being diluted with water, pH 4 to 12 is preferable, pH 7 to 11 is more preferable, pH 8 to 10 is further preferable, and pH 9 to 10 is particularly preferable. If it is less than the above lower limit value, the sterilizing power may be lowered or the anticorrosion property may be lowered, and if it exceeds the above upper limit value, the sterilizing power may be lowered. pH (25 degreeC) shows the value measured based on JISK3362-1998 using a pH meter (Horiba F-22, Horiba Ltd. make).

<(A) component>
The component (A) is N, N-bis (3-aminoalkyl) alkylamine represented by the following general formula (I). By containing (A) component, a bactericidal composition can exhibit bactericidal power, suppressing the corrosion of a metal member (corrosion prevention).

^{_{R 1 -N [(CH 2)}} n -NH 2] 2 ··· (I)
[In the formula (I), R ¹ represents an alkyl group having 8 to 18 carbon atoms, and n is a number of 1 to 4. ]

R ¹ may be linear or branched, and is preferably linear. If R ¹ is a straight chain, the bactericidal power of the bactericidal composition can be further increased.
The number of carbon atoms of R ¹ is 8 to 18, 8 to 14 are preferred, 12 is more preferred. If it is less than the lower limit, the sterilizing power is lowered, and if it exceeds the upper limit, the solubility in water is lowered.

 n is a number of 1 to 4, preferably 2 to 4, and more preferably 3. If it is within the above range, good sterilizing power can be exhibited.

 As such component (A), N, N-bis (3-aminomethyl) octylamine, N, N-bis (3-aminomethyl) decylamine, N, N-bis (3-aminomethyl) dodecylamine N, N-bis (3-aminomethyl) alkylamine such as N, N-bis (3-aminoethyl) octylamine, N, N-bis (3-aminoethyl) decylamine, N, N-bis (3 N, N-bis (3-aminoethyl) alkylamine such as -aminoethyl) dodecylamine; N, N-bis (3-aminopropyl) octylamine, N, N-bis (3-aminopropyl) decylamine, N N, N-bis (3-aminopropyl) alkylamine such as N, bis (3-aminopropyl) dodecylamine; N, N-bis (3-aminobutyl) octylamine, N, N, N-bis (3-aminobutyl) alkylamine such as bis (3-aminobutyl) decylamine, N, N-bis (3-aminobutyl) dodecylamine, etc., among others, N, N-bis (3-Aminopropyl) alkylamine is preferred, and N, N-bis (3-aminopropyl) dodecylamine is more preferred.

The content of the component (A) in the bactericidal composition can be determined in consideration of the dosage form of the bactericidal composition. For example, the content of the component (A) in the concentrated liquid sterilizing composition that is used after being poured into water is preferably 0.01 to 10% by mass, more preferably 0.1 to 3% by mass. Preferably, 0.3-3 mass% is more preferable. If it is less than the lower limit, the sterilizing power may be insufficient, and if it exceeds the upper limit, the liquid stability may be impaired.
Alternatively, the content of the component (A) in the straight type liquid bactericidal composition used without being diluted with water is preferably 0.1 mass ppm or more, more preferably 1 mass ppm or more, and 3 mass ppm or more. Is more preferable. The greater the content of the component (A), the better the bactericidal power against a wide range of microorganisms. For example, for sensitive Escherichia coli, if the content of component (A) is 0.1 mass ppm, sufficient bactericidal power is exhibited, and for less sensitive S. aureus, component (A) If the content of is 3 mass ppm or more, sufficient sterilizing power can be exhibited.
The upper limit of the content of the component (A) in the straight type liquid bactericidal composition is not particularly limited, and is preferably, for example, 10000 mass ppm or less, more preferably 1000 mass ppm or less, and further preferably 100 mass ppm or less. . Thus, even if there is little content of (A) component, the bactericidal composition of this invention can exhibit favorable bactericidal power.

  For example, the content of the component (A) in the solid bactericidal composition is preferably 0.01 to 10% by mass, more preferably 0.1 to 3% by mass, and further 0.3 to 3% by mass. preferable. If it is less than the lower limit, the sterilizing power may be insufficient, and if it exceeds the upper limit, the form stability of the solid sterilizing composition may be impaired.

<(B) component>
(B) A component is 1 or more types selected from the group which consists of silver, zinc, and copper. By containing the component (B), the bactericidal composition can enhance the anticorrosive property against the metal member and can enhance the bactericidal power of the component (A).

 (B) As a component, zinc is preferable. This is because silver may blacken the object to be processed and copper may discolor the object to be processed. In addition, the anticorrosive property tends to be zinc> copper ≧ silver.

(B) component may be mix | blended with the bactericidal composition as various metal compounds.
The metal compound of component (B) is not particularly limited as long as it is soluble in water. For example, inorganic salts such as nitrates, sulfates, chlorides, perchloric acid peroxides, ammonium chloride salts, cyanides, acetates, glucones, etc. Water-soluble metal salts such as organic salts such as acid salts, tartrate salts, and glycine salts.

The water-soluble silver salt is not particularly limited as long as it is soluble in water and releases silver ions at that time. For example, silver sulfate, silver nitrate, silver acetate, silver fluoride, silver perchlorate Among them, silver sulfate and hydrates thereof are preferable from the viewpoint of handleability and odor.
The water-soluble copper salt is not particularly limited as long as it is soluble in water and releases copper ions at that time. For example, copper nitrate, copper sulfide, copper sulfate, copper chloride, copper acetate, cyanide Examples include copper chloride, ammonium chloride copper, copper gluconate, copper tartrate, copper perchlorate and hydrates thereof, among others, copper sulfate, copper chloride, glucone in terms of handleability, cost, raw material supply, etc. Copper acid and their hydrates are preferred, and copper sulfate and its hydrates are preferred.
The water-soluble zinc salt is not particularly limited as long as it dissolves in water and releases zinc ions at that time. For example, zinc nitrate, zinc sulfide, zinc sulfate, zinc chloride, zinc acetate, cyanide Zinc chloride, ammonium zinc chloride, zinc gluconate, zinc tartrate, zinc perchlorate and their hydrates, among others, zinc sulfate, zinc chloride, glucone in terms of handling, cost, raw material supply, etc. Zinc acid and hydrates thereof are preferred, and zinc sulfate and hydrates thereof are more preferred.

The content of the component (B) in the bactericidal composition can be determined in consideration of the dosage form of the bactericidal composition. The content of the component (B) in the straight type liquid bactericidal composition used without being diluted with water can be determined in consideration of the type of the component (B), and if the component (B) is silver, 0.01 mass ppm or more is preferable, 0.069 mass ppm or more is more preferable, and 0.69 mass ppm or more is more preferable. This is because a sufficient bactericidal effect can be obtained if the lower limit is exceeded.
Moreover, when (B) component is copper, 0.013 mass ppm or more is preferable, as for content of (B) component in a straight type liquid bactericidal composition, 0.13 mass ppm is more preferable, 0 More preferably 5 ppm by mass or more. This is because a sufficient bactericidal effect can be obtained if the lower limit is exceeded.
When the component (B) is zinc, the content of the component (B) in the straight type liquid bactericidal composition is preferably 0.012 mass ppm or more, more preferably 0.12 mass ppm or more, and 23 mass ppm or more is more preferable. This is because a sufficient bactericidal effect can be obtained if the lower limit is exceeded.
The content of the component (A) in the concentrated liquid bactericidal composition used after being poured into water and diluted is preferably 0.012 to 3% by mass, more preferably 0.12 to 3% by mass, 0.23-3 mass% is further more preferable. If it is less than the lower limit, the sterilizing power may be insufficient, and if it exceeds the upper limit, the liquid stability may be impaired.

  Moreover, for example, the content of the component (B) in the solid bactericidal composition is preferably 0.012 to 3% by mass, more preferably 0.12 to 3% by mass, and further 0.23 to 3% by mass. preferable. If it is less than the lower limit, the sterilizing power may be insufficient, and if it exceeds the upper limit, the form stability of the solid sterilizing composition may be impaired.

 The content of the component (B) in the bactericidal composition can be determined in consideration of the content of the component (A). For example, the molar ratio represented by the component (A) / component (B) (hereinafter, ( A) / (B) ratio) is preferably from 0.1 to 100, more preferably from 0.3 to 20, and even more preferably from 0.5 to 6. This is because within the above range, the synergistic effect of the component (A) and the component (B) appears remarkably.

<Optional component>
The bactericidal composition of the present invention is an oxygen-based bactericidal agent, bleach activator, surfactant, inorganic salt (excluding the component (B)), organic acid salt (provided that the effect of the present invention is not impaired) , (B) component), polymer compounds, swellable water-insoluble minerals, pH adjusting agents, pH buffering agents, enzymes, pigments, fragrances and the like.

≪Oxygen-based disinfectant≫
Examples of the oxygen-based disinfectant include hydrogen peroxide or a peroxide that dissolves in water to generate hydrogen peroxide. By using an oxygen-based bactericidal agent in combination, the bactericidal power against both gram-positive and gram-negative bacteria can be further enhanced.
Examples of the peroxide that dissolves in water to generate hydrogen peroxide include sodium percarbonate, sodium perborate, sodium perborate trihydrate, and the like.

 The content of the oxygen-based bactericidal agent in the bactericidal composition can be determined in consideration of the dosage form and the like. For example, 0.0001 to 20% by mass is preferable, and 0.0005 to 5% by mass is more preferable. If the amount is less than the above lower limit value, the sterilizing power may not be further improved, and if it exceeds the above upper limit value, the workpiece may be damaged.

≪Bleach activator≫
Bleach activators include sodium octanoyloxybenzenesulfonate, sodium nonanoyloxybenzenesulfonate, sodium decanoyloxybenzenesulfonate, sodium undecanoyloxybenzenesulfonate, sodium dodecanoyloxybenzenesulfonate, octanoyl Oxybenzoic acid, Nonanoyloxybenzoic acid, Decanoyloxybenzoic acid, Undecanoyloxybenzoic acid, Dodecanoyloxybenzoic acid, Octanoyloxybenzene, Nonanoyloxybenzene, Decanoyloxybenzene, Undecanoyloxybenzene, Dodecanoyl Examples thereof include oxybenzene.

≪Surfactant≫
Examples of the surfactant include conventionally known anionic surfactants, nonionic surfactants, cationic surfactants, and amphoteric surfactants. Since the bactericidal composition contains a surfactant, the detergency increases, and it is suitably used as a cleaning agent.

As an anionic surfactant, the following are mentioned, for example.
(1) A linear or branched alkylbenzene sulfonate (LAS or ABS) having an alkyl group having 8 to 18 carbon atoms.
(2) Alkanesulfonate having 10 to 20 carbon atoms.
(3) C10-20 α-olefin sulfonate (AOS).
(4) Alkyl sulfate or alkenyl sulfate (AS) having 10 to 20 carbon atoms.
(5) Any of alkylene oxides having 2 to 4 carbon atoms, or ethylene oxide (EO) and propylene oxide (PO) (molar ratio EO / PO = 0.1 / 9.9 to 9.9 / 0.1) Alkyl (or alkenyl) ether sulfate (AES) having a linear or branched alkyl (or alkenyl) group having 10 to 20 carbon atoms to which an average of 0.5 to 10 mol is added.
(6) Any of alkylene oxides having 2 to 4 carbon atoms, or ethylene oxide (EO) and propylene oxide (PO) (molar ratio EO / PO = 0.1 / 9.9 to 9.9 / 0.1) An alkyl (or alkenyl) phenyl ether sulfate having a linear or branched alkyl (or alkenyl) group having 10 to 20 carbon atoms with an average of 3 to 30 moles added thereto.
(7) Any of alkylene oxides having 2 to 4 carbon atoms, or ethylene oxide (EO) and propylene oxide (PO) (molar ratio EO / PO = 0.1 / 9.9 to 9.9 / 0.1) An alkyl (or alkenyl) ether carboxylate having a linear or branched alkyl (or alkenyl) group having 10 to 20 carbon atoms to which 0.5 to 10 mol of an average is added.
(8) Alkyl polyhydric alcohol ether sulfates such as alkyl glyceryl ether sulfonic acids having 10 to 20 carbon atoms.
(9) C8-20 saturated or unsaturated α-sulfo fatty acid salt (α-SF) or a methyl, ethyl or propyl ester thereof.
(10) Long chain monoalkyl, dialkyl or sesquialkyl phosphates.
(11) Polyoxyethylene monoalkyl, dialkyl or sesquialkyl phosphate.
(12) A higher fatty acid salt (soap) having 10 to 20 carbon atoms.
These anionic surfactants are used as alkali metal salts such as sodium and potassium, amine salts and ammonium salts. These anionic surfactants may be used as a mixture.

The nonionic surfactant is not particularly limited as long as it is conventionally used for a cleaning agent, and examples thereof include the following.
(1) An average of 3 to 30 moles, preferably 4 to 20 moles, more preferably 5 to 17 moles of an alkylene oxide having 2 to 4 carbon atoms is added to an aliphatic alcohol having 6 to 22 carbon atoms, preferably 8 to 18 carbon atoms. Polyoxyalkylene alkyl (or alkenyl) ether. Among these, polyoxyethylene alkyl (or alkenyl) ether and polyoxyethylene polyoxypropylene alkyl (or alkenyl) ether are preferable. Examples of the aliphatic alcohol used here include primary alcohols and secondary alcohols. The alkyl group may have a branched chain. As the aliphatic alcohol, a primary alcohol is preferable.
(2) Polyoxyethylene alkyl (or alkenyl) phenyl ether.
(3) A fatty acid alkyl ester alkoxylate represented by, for example, the following general formula (i) in which an alkylene oxide is added between ester bonds of a long-chain fatty acid alkyl ester.

R ³ CO (OA) _p OR ⁴ (i)

In (i), R ³ CO represents a fatty acid residue having 6 to 22, preferably 8 to 18 carbon atoms. OA represents an addition unit of an alkylene oxide having 2 to 4 carbon atoms, preferably 2 to 3 carbon atoms such as ethylene oxide and propylene oxide. p shows the average addition mole number of alkylene oxide, and is generally 3-30, Preferably it is the number of 5-20. R ⁴ is a lower alkyl group which may have a substituent having 1 to 3 carbon atoms.

(4) Polyoxyethylene sorbitan fatty acid ester.
(5) Polyoxyethylene sorbite fatty acid ester.
(6) Polyoxyethylene fatty acid ester.
(7) Polyoxyethylene hydrogenated castor oil.
(8) Glycerin fatty acid ester.
(9) Fatty acid alkanolamide.
(10) Polyoxyethylene alkylamine.
(11) Alkyl glycoside.
(12) Alkylamine oxide.

As a cationic surfactant, if it is conventionally used for a washing | cleaning agent, it will not specifically limit, For example, the following are mentioned.
(1) Dilong chain alkyl dishort chain alkyl type quaternary ammonium salt.
(2) Mono long chain alkyl tri short chain alkyl type quaternary ammonium salt.
(3) Tri long chain alkyl mono short chain alkyl type quaternary ammonium salt.
(The long-chain alkyl represents an alkyl group having 12 to 26 carbon atoms, preferably 14 to 18 carbon atoms. The short-chain alkyl is an alkyl group having 1 to 4 carbon atoms, preferably 1 to 2 carbon atoms, a benzyl group, and 2 to 4 carbon atoms. And preferably represents 2-3 hydroxyalkyl groups or polyoxyalkylene groups.)

The amphoteric surfactant is not particularly limited as long as it is conventionally used for a cleaning agent, and various amphoteric surfactants can be mentioned.
These surfactants may be used singly or in combination of two or more.

 The content of the surfactant in the bactericidal composition is appropriately determined in consideration of the use of the bactericidal composition.

≪Inorganic salts≫
Examples of inorganic salts include sodium carbonate, potassium carbonate, sodium bicarbonate, sodium sulfite, sodium sesquicarbonate, sodium silicate, sodium metasilicate, crystalline layered sodium silicate, non-crystalline layered sodium silicate, and other alkaline salts such as sodium sulfate. Neutral salts, orthophosphates, pyrophosphates, tripolyphosphates, metaphosphates, hexametaphosphates, phosphates such as phytate, crystalline aluminosilicates represented by the following general formula (ii), Inorganic ammonium salts such as amorphous aluminosilicates represented by general formulas (iii) and (iv), ammonium sulfate, ammonium chloride, and the like can be given.

α ¹ (M ₂ O) · Al ₂ O ₃ · β ¹ (SiO ₂ ) · γ ¹ (H ₂ O) (ii)

(Ii) In the formula, M represents an alkali metal atom such as sodium or potassium, α ¹ , β ¹ and γ ¹ represent the number of moles of each component, generally α ¹ is 0.7 to 1.5, β ¹ is a number from 0.8 to 6, and γ ¹ is an arbitrary positive number.

α ² (M ₂ O) · Al ₂ O ₃ · β ² (SiO ₂ ) · γ ² (H ₂ O) (iii)

(Iii) In the formula, M represents an alkali metal atom such as sodium or potassium, α ² , β ² and γ ² represent the number of moles of each component, and generally α ² is 0.7 to 1.2, β ² represents 1.6 to 2.8, and γ ² represents 0 or an arbitrary positive number.

α ³ (M ₂ O) · Al ₂ O ₃ · β ³ (SiO ₂ ) · η ¹ (P ₂ O ₅ ) · γ ³ (H ₂ O) (iv)

(Iv) In the formula, M represents an alkali metal atom such as sodium or potassium, α ³ , β ³ , η ¹ and γ ³ represent the number of moles of each component, and generally α ³ is 0.2 to 1 .1, β ³ is 0.2 to 4.0, η ¹ is 0.001 to 0.8, and γ ³ is 0 or any positive number.

≪Organic acid salts≫
Examples of the organic acid salts include aminocarboxylates such as nitrilotriacetate, ethylenediaminetetraacetate, β-alanine diacetate, aspartate diacetate, methylglycine diacetate, and iminodisuccinate; serine diacetate, hydroxyimino Hydroxyaminocarboxylates such as disuccinate, hydroxyethylethylenediamine triacetate, dihydroxyethylglycine; Hydroxycarboxylates such as hydroxyacetate, tartrate, citrate, gluconate; pyromellitic acid salt, Cyclocarboxylates such as benzopolycarboxylate and cyclopentanetetracarboxylate; ether carboxylates such as carboxymethyl tartronate, carboxymethyl oxysuccinate, oxydisuccinate, monotartaric acid or disuccinate, p-to Sodium ene sulfonate, sodium xylene sulfonate, benzenesulfonate having short-chain alkyl of 1 to 5 carbon atoms sodium queue Men sulfonic acid, sodium benzoate, and sodium benzene sulfonate and the like.

≪Polymer compound≫
Examples of the polymer compound include acrylic acid polymer compounds, polyacetal carboxylates, itaconic acid, fumaric acid, tetramethylene-1,2-dicarboxylic acid, succinic acid, aspartic acid and other polymers or copolymers, polyethylene glycol , Cellulose derivatives such as carboxymethyl cellulose, polyvinylpyrrolidone and derivatives thereof, and silicone oil.

≪Water-soluble organic substances≫
Examples of water-soluble organic substances include D-glucose, urea, and sucrose.
≪Swellable water-insoluble substance≫
Examples of the swellable water-insoluble substance include clay minerals such as smectite.

≪pH adjuster≫
Examples of the pH adjuster include hydrochloric acid, sulfuric acid, nitric acid, citric acid, phosphoric acid, sodium hydroxide, potassium hydroxide, sodium carbonate, sodium citrate, sodium hydrogen citrate, sodium phosphate, sodium hydrogen phosphate and the like. Can be mentioned.

≪pH buffering agent≫
As the pH buffer, a conventionally known pH buffer can be used, alkanolamine is preferable, monoethanolamine, diethanolamine, and triethanolamine are more preferable, and monoethanolamine is more preferable. These pH buffer agents do not lower the liquid stability of the liquid bactericidal composition, and can further increase the bactericidal power of the bactericidal composition by adjusting the pH of the treatment liquid to an arbitrary range.

(Method for producing bactericidal composition)
The bactericidal composition of the present invention can be obtained by a conventionally known production method depending on the dosage form. For example, as a manufacturing method of a liquid bactericidal composition, the method of melt | dissolving (A) component, (B) component, and arbitrary components as needed in a solvent, and adjusting to arbitrary pH with a pH adjuster is mentioned. Examples of the solvent include water, a mixture of water and alcohol, and the like.
As a manufacturing method of a solid bactericidal composition, (A) component, (B) component, and the method of mixing arbitrary components as needed and obtaining the granular bactericidal composition are mentioned. Or the method of obtaining the particle | grains which contain the (A) component and powder-mixing this and (B) component and obtaining a granular bactericidal composition is mentioned. Furthermore, the manufacturing method which shape | molds a granular bactericidal composition in a tablet, a briquette, a sheet | seat, a bar, etc. is mentioned.
In addition, for example, (A) component, (B) component and optional components are kneaded, and this is molded into tablets, briquettes, sheets, bars, etc., and the resulting kneaded product is pulverized. Examples include a production method in which granulation or extrusion granulation is performed to form granules.
Alternatively, there may be mentioned those in which the component (A), the component (B) and the optional component are individually powdered.

(how to use)
The method for using the bactericidal composition of the present invention, that is, the bactericidal method of the present invention is to bring the bactericidal composition of the present invention into contact with an object to be treated.
The material to be treated is not particularly limited, and for example, conventional sterilizing compositions to be treated, such as textile products such as clothing, fabrics and carpets, and hard surfaces such as ceramics, glass, metal, and plastics. Can be mentioned.

 As a method of bringing the bactericidal composition into contact with the object to be treated, in the case of a straight type liquid bactericidal composition, the object to be treated is immersed in the liquid bactericidal composition or the liquid bactericidal composition is treated. And the like.

 In the case of a concentrated liquid sterilizing composition or solid sterilizing composition, these are dissolved in water to form a treatment liquid, and the treatment object is immersed in the obtained treatment liquid, or the treatment liquid is sprayed on the treatment object. The method of doing is mentioned. Alternatively, after preparing the first treatment liquid containing the component (A) and the second treatment liquid containing the component (B), contacting the first treatment liquid with the workpiece, Examples thereof include a method of bringing the second treatment liquid into contact with the object to be treated, a method of bringing the second treatment liquid into contact with the object to be treated, and then bringing the first treatment liquid into contact with the object to be treated. However, if the first treatment liquid is brought into contact with the workpiece after the second treatment liquid is brought into contact with the workpiece, the sterilizing power may be reduced. For this reason, when using a 1st process liquid and a 2nd process liquid, after making a 1st process liquid contact a to-be-processed object, a 2nd process liquid can be made to contact a to-be-processed object. preferable.

The concentration of the bactericidal composition in the treatment liquid can be determined according to the contents of the component (A) and the component (B) in the bactericidal composition. For example, the content of the component (A) in the treatment liquid is preferably 0.1 mass ppm or more, more preferably 1 mass ppm or more, and further preferably 3 mass ppm or more. The greater the content of component (A) in the treatment liquid, the better the bactericidal power against a wide range of microorganisms. For example, for Escherichia coli having high sensitivity, if the content of the component (A) in the treatment liquid is 0.1 mass ppm, sufficient bactericidal power is exerted, and for Staphylococcus aureus having low sensitivity, If content of (A) component in a process liquid is 3 mass ppm or more, it can fully exhibit bactericidal power.
Moreover, 0.01 mass ppm or more is preferable, as for content of (B) component in a process liquid, 0.069 mass ppm or more is more preferable, and 0.69 mass ppm or more is further more preferable. This is because a sufficient bactericidal effect can be obtained if the lower limit is exceeded.

The molar concentration of the component (A) in the treatment liquid is, for example, preferably 0.3 μM / L to 10 mM / L, and more preferably 10 μM / L to 1 mM / L. If it is less than the lower limit, the sterilizing power may be reduced, and even if the upper limit is exceeded, the sterilizing power is saturated.
For example, the molar concentration of the component (B) in the treatment liquid is preferably 30 nM / L to 10 mM / L, and more preferably 2.3 μM / L to 100 μM / L. If the amount is less than the lower limit, the sterilizing power may be reduced, and if it exceeds the upper limit, precipitates are likely to be generated.

 The treatment liquid is preferably pH 4 to 12, more preferably pH 7 to 11, further preferably pH 8 to 10, and particularly preferably pH 9 to 10. If it is less than the above lower limit value, the sterilizing power may be lowered or the anticorrosion property may be lowered, and if it exceeds the above upper limit value, the sterilizing power may be lowered. The pH of the treatment liquid can be adjusted using a pH adjuster.

The temperature of the treatment liquid is, for example, 0 to 65 ° C. Within the above temperature range, the effect of the present invention is remarkably exhibited.
The time for which the treatment liquid is brought into contact with the object to be treated can be determined in consideration of the concentration of the component (A) in the treatment liquid, for example, 10 minutes or more.

  As above-mentioned, since the bactericidal composition of this invention contains (A) component and (B) component, it can exhibit the outstanding bactericidal power, suppressing the corrosion of a metal member. Although the mechanism by which the bactericidal composition of the present invention exhibits excellent bactericidal power is not clear, the component (A) and the component (B) form a complex in the treatment liquid, and this complex adheres to the object to be treated. It is presumed to show a high bactericidal effect against the microorganisms.

  The disinfectant of the present invention includes, for example, clothing cleaning agents, clothing softeners, clothing bleaching agents, clothing finishing agents such as clothing finishing agents, kitchen detergents, garbage disinfectants, disinfectants for cleaning appliances, For washing machine cleaner, air conditioner / air cleaner cleaner, filter sterilizer, pipe cleaner, hard surface sterilizer, pool sterilizer, fuel tank sterilizer, hand sanitizer, body sanitizer, etc. It can be suitably applied.

  EXAMPLES Hereinafter, although an Example is shown and this invention is demonstrated in detail, this invention is not limited by the following description.

(Raw materials used)
<(A) component>
A-1: Triamine Y12D (N, N-bis (3-aminopropyl) dodecylamine (CAS number 2372-82-9), manufactured by Lion Akzo Co., Ltd.)
A-2: Triamine T (N, N-bis (3-aminopropyl) alkylamine derived from beef tallow, manufactured by Lion Akzo Corporation)
<(A ′) component: Comparative product of component (A)>
A′-1: Duomine CD (coconut oil-derived alkylpropylenediamine, manufactured by Lion Akzo Co., Ltd.)

<(B) component>
B-1: Silver sulfate, manufactured by Wako Pure Chemical Industries, Ltd. B-2: Copper sulfate pentahydrate, manufactured by Kanto Chemical Co., Ltd. B-3: Zinc sulfate heptahydrate, manufactured by Kanto Chemical Co., Ltd. <(B ' ) Ingredient: Comparison product of (B) ingredient>
B′-1: Manganese sulfate monohydrate, manufactured by Kanto Chemical Co., Inc.

<Optional component>
Nonionic surfactant: LMAO (alcohol ethoxylate with an average of 15 moles of ethylene oxide added per mole of lauryl alcohol), manufactured by Lion Chemical Co., Ltd. Benzalkonium chloride: Osban solution, manufactured by Nippon Pharmaceutical Co., Ltd. Ethanol: Kanto Chemical Co., Inc. Company 0.1N sulfuric acid: manufactured by Kanto Chemical Co. 1N sulfuric acid: manufactured by Kanto Chemical Co., Ltd. Monoethanolamine: manufactured by Kanto Chemical Co., Ltd. Diethanolamine: manufactured by Kanto Chemical Co., Ltd.

(Evaluation method)
<Bactericidal power>
Escherichia coli NBRC3972 was inoculated with a platinum loop in an SCD agar medium manufactured by Daigo and cultured at 37 ° C. for 24 hours. Colonies grown using platinum ears were collected, suspended in sterilized water, adjusted to 1 × 10 ⁸ / mL, and used as an E. coli suspension. Similarly, a 1 × 10 ⁸ / mL staphylococcal suspension of Staphylococcus aureus NBRC12732 was prepared.
JIS Kanaki No. 3 was cut into a 1 cm square, and about 0.3 g was put into a 50 mL capacity centrifuge tube and sterilized by high-pressure steam. Here, 10 mL of the treatment solution of each example was added and stirred, and then 0.01 mL of E. coli suspension or staphylococcal suspension was added. When the E. coli suspension was added, it was left at 25 ° C. for 10 minutes, and when the staphylococcal suspension was added, it was left at 25 ° C. for 3 minutes. After standing, 0.3 mL was extracted and added to 2.7 mL of Daigo SCDLP medium. 0.3 mL of this was diluted sequentially with 2.7 mL of Japanese Pharmacopoeia phosphate buffer, 1 mL of each was mixed with SCDLP agar medium manufactured by Daigo, and then pour-cultured at 37 ° C. The number of bacteria (V1) was determined. Similarly, the viable cell count (VO) was determined using purified water instead of the treatment liquid, and the bactericidal activity value (ΔLOG) was determined by the following formula (1).

Bactericidal activity value (ΔLOG): log ₁₀ (V0) −log ₁₀ (V1) (1)

<Evaluation of corrosion resistance>
The dry-cut cast iron chips (FC-25, 8-12 mesh) were washed with chloroform and dried. About 5 g of dried chips were immersed in the treatment liquid of each example for 10 minutes, spread on a petri dish with filter paper (Advantech No. 2, manufactured by Whatman), and left at room temperature (25 ° C.). The presence or absence of rust after standing for 24 hours was visually observed, and corrosion resistance was evaluated according to the following evaluation criteria.

≪Evaluation criteria≫
A: No generation of rust is observed. ○: 1 to 9 rusts are recognized, and the total area is less than half of the entire area. Δ: 10 or more and less than half of the entire area. : Rust occurs in more than half of the entire area

(Examples 1-40, Comparative Examples 1-14)
According to the composition of Tables 1-5, each component was melt | dissolved in purified water and the process liquid (1000 mL) of each example was obtained. About the obtained processing liquid, the bactericidal activity value with respect to colon_bacillus | E._coli or Staphylococcus aureus, and anticorrosion property were evaluated, and the result is shown in a table | surface. In addition, the composition of each component in a table | surface is a pure conversion amount (the same is hereafter).

(Examples 41 to 42)
According to the composition composition of Table 6, each component was dissolved in purified water to obtain a bactericidal composition (1000 mL) of each example. 1 part by mass of the obtained bactericidal composition was added to 999 parts by mass of diluted water of 3 ° DH to obtain a treatment liquid for evaluating bactericidal activity. About this process liquid, the bactericidal activity value with respect to colon_bacillus | E._coli is evaluated, and the result is shown in a table | surface. Further, 1 part by mass of the obtained bactericidal composition was added to 999 parts by mass of tap water in Hirai, Edogawa-ku, Tokyo to obtain a treatment liquid for evaluating corrosion resistance. About this process liquid, anticorrosion property was evaluated and the result is shown in a table | surface.
The 3 ° DH dilution water was prepared by the following procedure. First, purified water was added to 59.3 g of calcium chloride dihydrate and 27.21 g of magnesium chloride hexahydrate to prepare 1000 mL of hard water, and 1 part by mass of this hard water was sterilized water. Dilution water was obtained by mixing with 999 parts by mass.

As shown in Tables 1 to 4, in Examples 1 to 33 to which the present invention was applied, the bactericidal activity value (ΔLOG) against E. coli was 1.5 or more, and the anticorrosive property was “◯” or “◎”. It was. Among Examples 2 and 10 to 15, Examples 12 to 14 having a pH of 8 to 10 had particularly high bactericidal activity values.
On the other hand, Comparative Examples 1 and 2, which do not contain the component (B), each had a low bactericidal activity value (ΔLOG) against E. coli of 0.7 or less. In Comparative Examples 3 to 5 that do not contain the component (A), the bactericidal activity value against Escherichia coli was 0.3 or less. In Comparative Examples 7 to 8 using duomin CD instead of the component (A), the bactericidal activity value against Escherichia coli was 1.2 or less. In Comparative Example 6 using benzalkonium chloride instead of the components (A) to (B), the anticorrosion property is “x”, and hydrogen peroxide is used instead of the components (A) to (B). In Comparative Example 10, the bactericidal activity value (ΔLOG) against E. coli was 0. In Comparative Example 9 using manganese instead of the component (B), the bactericidal activity value (ΔLOG) against Escherichia coli was 0.5.

As shown in Table 5, in Examples 34 to 40 to which the present invention was applied, the bactericidal activity value (ΔLOG) against S. aureus was 3.2 or more, and the anticorrosive property was “◎”.
On the other hand, Comparative Example 11 containing no component (B) and Comparative Example 12 containing no component (A) have a bactericidal activity value (ΔLOG) against S. aureus of 1.2 or less and an anticorrosive property of “Δ "Met. Further, Comparative Example 13 using benzalkonium chloride in place of the components (A) to (B) has an anticorrosion property of “x”, and instead of the components (A) to (B), hydrogen peroxide is used. In Comparative Example 14 used, the bactericidal activity value (ΔLOG) against Staphylococcus aureus was 0, and the anticorrosive property was “x”.

As shown in Table 6, in Examples 41 to 42 to which the present invention was applied, the bactericidal activity value against Escherichia coli was 2.1 or more, and the anticorrosive property was “◎”.
From the above results, it was found that by applying the present invention, the corrosion of the metal member can be suppressed and the sterilizing power can be enhanced.

Claims (2)

(A) component: N, N-bis (3-aminoalkyl) alkylamine represented by the following general formula (I);
(B) Component: One or more selected from the group consisting of silver, zinc and copper, and a bactericidal composition.
^{_{R 1 -N [(CH 2)}} n -NH 2] 2 ··· (I)
[In the formula (I), R ¹ represents an alkyl group having 8 to 18 carbon atoms, and n is a number of 1 to 4. ]   The bactericidal composition according to claim 1, wherein the component (A) is N, N-bis (3-aminopropyl) alkylamine.