JP2013059376A - Medical liquid transport pipe, medical liquid transport device, and medical liquid transport method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a medical liquid transport pipe, a medical liquid transport device, and a medical liquid transport device which suppress the change of temperature of the medical liquid and deal with sterilization treatment by steam.SOLUTION: The medical liquid transport pipe 1 has an inner tube 2, an outer tube 3, and a support member 4 for holding an interval between the inner tube 2 and the outer tube 3. The inside of the inner tube 2 is the flow path 6 of objects to be transported. A annular space 7 held between the inner tube 2 and the outer tube 3 is formed so as to be depressurized, and there is a bend part 23 in a route. By depressurizing the circular space 7, a heat insulating effect is achieved, and by having the bend part 23, the medical transport pipe 1 can deal with a difference in thermal expansion between the inner tube 2 and the outer tube 3.

Description

  The present invention relates to a transport pipe, a transport device, and a transport method for transporting a liquid medicine.

  Many pharmaceutical products require temperature control to maintain their quality. In particular, bio-derived drugs such as biologics and blood products are kept at a constant temperature of 3 to 4 ° C. in order to prevent activities such as bacterial growth. This also applies to the manufacturing process of undiluted solutions such as biopharmaceuticals and injection solutions. When transporting these liquid medicines (pharmaceutical solutions) through piping, etc., the temperature is kept constant at 3 to 4 ° C. Transported.

  Therefore, a multiple tube as shown in FIG. 3 is used for the medical solution transport tube. In FIG. 3, the innermost layer is a flow path 16 of the pharmaceutical liquid to be transported, an annular space 17 sandwiched between the inner tube 12 and the outer tube 13 is a refrigerant flow path, and the outermost layer is a heat insulating material 15. With this structure, the pharmaceutical solution is transported while being cooled by the refrigerant.

  In fields other than drug solution transportation, a vacuum heat insulating tube having a double structure may be used. Patent Document 1 describes a heat insulating pipe in which a space sandwiched between an inner pipe and an outer pipe of a double pipe is evacuated as a heat insulating pipe suitable for use in a water pipe or the like in a cold region. Patent Document 2 describes that chemical raw materials, semiconductor raw materials, and the like are transported while a vacuum pump is used to evacuate and maintain a vacuum between an inner tube and an outer tube of a double structure tube. Patent Document 3 describes that a vacuum heat insulating double pipe is used for transferring a liquefied gas in a cryogenic temperature region, and further, in order to absorb a difference in heat shrinkage caused by a temperature difference between the inner and outer pipes, It is described that an inner tube bellow (a bellows-like stretchable tube) is provided in the middle of the tube.

JP-A-62-204096 JP-A-8-285147 Japanese Utility Model Publication No. 57-94779

  However, in the transport pipe using the refrigerant, the entire apparatus is complicated due to the refrigerant circulation system, and there is a problem with the sterilization operation of the medical fluid flow path. In transporting the pharmaceutical solution, the flow path is sterilized with pure steam or the like before the start of transport. On the other hand, the refrigerant is often a mixture of water and a small amount of alcohol to lower the freezing point. If the temperature of the transport pipe rises to 100 ° C. or more due to pure vapor, the refrigerant may boil and change its quality, or the transport pipe or the refrigerant circulation system may be deformed or damaged by the refrigerant vapor. For this reason, work such as discharging all the refrigerant from the transport pipe before sterilization with pure steam and returning it to the transport pipe after sterilization processing was performed, which was troublesome.

  Even if the vacuum heat insulating tube is used, the conventional vacuum heat insulating tube has some problems when used for transporting a pharmaceutical solution. In the vacuum heat insulating tube described in Patent Document 1, the space sandwiched between the inner tube and the outer tube is sealed in advance in a vacuum state. However, it is costly to form a seal for maintaining a vacuum state, and even if such a seal is formed, it is inevitable that the degree of vacuum in the space gradually decreases during long-term use.

  Furthermore, the temperature difference between the inner and outer tubes becomes very large in the sterilization process using pure steam, but Patent Documents 1 and 2 describe a method for absorbing the difference in thermal expansion caused by the temperature difference between the inner and outer tubes. Absent. Patent Document 3 describes that an inner tube bellow is provided in the middle of the inner tube in order to absorb the heat shrinkage difference between the inner and outer tubes. However, it is necessary to avoid mixing different types of liquid medicines and washing water in the medicine liquid transport pipe, and flow of bellows-shaped bellows where the liquid medicine tends to remain after the transportation process and the washing water tends to remain after the washing process. It is not desirable to use it on the road.

  The present invention has been made in consideration of the above points, and an object of the present invention is to provide a transport pipe, a transport device, and a transport method suitable for transporting a pharmaceutical solution.

  The pharmaceutical solution transport pipe of the present invention has an inner tube, an outer tube, and a support member for maintaining a space between the inner tube and the outer tube, and the inside of the inner tube is a flow path of a transported article, An annular space sandwiched between the tube and the outer tube is formed so as to be able to be depressurized, and has a bent portion in the middle of the path. With this structure, the annular space can be decompressed to obtain a heat insulating effect. Further, since the transport pipe has a bent portion in the middle of the path, a difference in thermal expansion caused by the temperature difference between the inner and outer pipes can be absorbed by a simple structure. That is, even if a dimensional difference occurs between the inner tube and the outer tube, distortion caused by the difference can be alleviated and the transport tube can be prevented from being deformed or broken.

  Preferably, the support member is fixed to the inner pipe and is not fixed to the outer pipe, and the support member is provided at a portion other than the bent portion of the transport pipe. As a result, the difference in thermal expansion between the inner and outer tubes can be better absorbed.

  Preferably, the inner tube does not have a bellows-like expansion joint. This makes it difficult for pharmaceutical liquid, washing water, and the like to remain in the joint portion, and it is easy to prevent the pharmaceutical liquid and the like from being mixed into the next transported pharmaceutical liquid.

  The pharmaceutical liquid transport device of the present invention includes any one of the above pharmaceutical liquid transport pipes and an air cooler for supplying cold / warm air to the annular space of the pharmaceutical liquid transport pipe. As a result, even when the transportation of the pharmaceutical liquid is stopped for some reason, the temperature rise of the pharmaceutical liquid staying in the flow path can be suppressed by supplying the cold air to the annular space.

  The method for transporting a medicinal liquid according to the present invention uses any one of the medicinal liquid transport pipes described above, supplying pure vapor to the flow path of the medicinal liquid transport pipe, depressurizing the annular space, and And a step of circulating a pharmaceutical solution through the flow path while reducing the pressure. As a result, it is possible to transport the pharmaceutical solution while preventing contamination of bacteria and suppressing temperature changes.

  Preferably, in the method for transporting the pharmaceutical liquid, when the transport of the pharmaceutical liquid is stopped, the temperature of the pharmaceutical liquid staying in the flow path is suppressed by supplying cold / warm air to the annular space of the pharmaceutical liquid transport pipe. It is characterized by that. Thereby, even when the transportation of the pharmaceutical solution is stopped for some reason, the temperature rise of the pharmaceutical solution staying in the flow path can be suppressed.

  As described above, according to the pharmaceutical solution transport pipe of the present invention, it is possible to obtain a heat insulating effect by reducing the pressure of the annular space sandwiched between the inner pipe and the outer pipe of the double pipe structure, and the transport pipe is in the path. By having the bent portion in the middle, it is possible to absorb the difference in thermal expansion caused by the temperature difference between the inner and outer tubes. In addition, according to the pharmaceutical solution transport device of the present invention, it is possible to suppress the temperature rise of the pharmaceutical solution staying in the flow path even when the transport of the pharmaceutical solution is stopped for some reason. In addition, according to the method for transporting a pharmaceutical solution of the present invention, it is possible to transport a pharmaceutical solution while preventing contamination of bacteria and suppressing temperature changes.

It is a figure which shows the cross-sectional structure of the pharmaceutical liquid transport pipe | tube which is one Embodiment of this invention. It is a piping diagram of the pharmaceutical liquid transport pipe which is one embodiment of the present invention. It is a figure which shows the cross-section of the conventional pharmaceutical liquid transport pipe. It is a piping diagram of the conventional pharmaceutical liquid transport pipe. It is a piping diagram of the experimental apparatus which is an Example of this invention. It is sectional drawing of a bending part.

  One embodiment of the pharmaceutical liquid transport tube of the present invention will be described with reference to FIGS. 1 and 2.

  FIG. 1 shows a cross-sectional structure of the transport pipe of this embodiment. The transport pipe 1 of the present embodiment has a double pipe structure composed of an inner pipe 2 and an outer pipe 3, and has a plate-like support member 4 for holding a gap between the inner pipe 2 and the outer pipe 3. Yes. The inside of the inner tube 2 is a flow path 6 for a pharmaceutical solution. An annular space 7 sandwiched between the inner tube 2 and the outer tube 3 is formed to be depressurized.

  The diameter and thickness of the inner tube 2 and the outer tube 3 can be appropriately designed according to the application. Since the pharmaceutical solution to be transported is often a small amount, the inner tube 2 having an inner diameter of 14 to 48 mm can be suitably used. The material of the inner tube 2 and the outer tube 3 should be made of a heat-resistant material that can maintain the reduced pressure of the annular space without affecting the quality of the pharmaceutical solution to be transported and can withstand sterilization with pure steam. Can do. For example, stainless steel can be suitably used.

  The shape of the support member 4 requires that the gap between the inner tube 2 and the outer tube 3 can be maintained, and that the fluid resistance is not too large when the air in the annular space 7 is discharged. If there is no particular limitation. Although a plate-like support member is shown in FIG. 1, shapes other than the plate shape may be used. Moreover, although the annular support member without a cut | interruption was shown in FIG. 1, it may be a cyclic | annular thing with a cut | disconnection so that it may be easy to fit in an inner tube | pipe. The support member 4 may be made of a material having sufficient strength to maintain the gap between the inner tube 2 and the outer tube 3 and having heat resistance capable of withstanding sterilization with pure steam. For example, stainless steel can be suitably used.

  The support member 4 is preferably fixed to the inner tube 2 so as not to move due to vibrations or the like during use of the transport tube 1. The support member 4 is preferably not fixed to the outer tube 3. This is because if the support member is fixed to both the inner tube 2 and the outer tube 3, the transport tube 1 is deformed when a difference in thermal expansion occurs between the inner and outer tubes. Further, if the support material 4 is fixed only to the outer tube 3, it is difficult to assemble the transport tube 1. As a method of fixing the support member 4 to the inner tube 2, various methods such as welding, brazing, adhesion, and the like can be used.

  In FIG. 2, the piping system figure of the transport pipe and transport apparatus which are this embodiment is shown. From the upper left to the lower right of FIG. 2, the pharmaceutical liquid is transported through the flow path 6 from the flow path inlet 21 of the transport pipe 1 to the flow path outlet 22. The transport pipe 1 is formed with bent portions 23 at two locations. The flow path 6 is connected to a pure steam production machine 24 for performing a sterilization process, and is provided with a drain 25 and a temperature sensor 29 for flowing out the agglomerated water and the drug solution remaining in the flow path. . In addition, a pressure sensor 28 is provided in the annular space 7, and a vacuum pump 26 for reducing the pressure in the annular space and an air cooler 27 for supplying cold / warm air to the annular space are connected.

  The length of the transport pipe 1 is typically 10 to 50 m, but may extend to 100 m. It is preferable that there is no place in the path of the transport pipe 1 lower than before and after that so as to prevent accumulation of a medical solution or washing water in the flow path 6 after completion of transport. Moreover, it is preferable that there is no big level | step difference also in the joint part in the case of connecting the inner wall of the flow path 6, and the transport pipe 1. FIG. In addition, the entire path of the transport pipe 1 is provided with a gentle gradient, for example, 1/100 to 1/200, so that the drug solution, washing water, and the like in the flow path 6 can be easily discharged. preferable. In transporting a pharmaceutical solution, since different pharmaceutical solutions are often processed several times a day to a week, it is an important feature that the pharmaceutical solution, washing water, and the like are easily discharged from the flow path 6.

  Most of the transport pipe 1 or the transport device 20 according to the present embodiment is used in a pharmaceutical solution factory, and the atmospheric temperature of the installation place is often kept at 23 to 25 ° C. by air conditioning. On the other hand, sterilization with pure steam is often performed using steam at 120 to 140 ° C., typically about 132 ° C. (saturated steam temperature at an absolute pressure of 0.29 MPa). Therefore, it is necessary that the transport pipe for the medical liquid has a structure that can cope with the thermal expansion of the inner pipe 2. In the conventional medicinal liquid transport pipe 11 shown in FIG. 4, a unit 18 having a length of about 2 m or less is produced and is often used by connecting it with a joint. On the other hand, in the present embodiment, it is possible to configure the entire path with one transport pipe 1 by providing the bent portion 23. This is because even when a difference in thermal expansion occurs between the inner and outer tubes, the difference in length between the inner and outer tubes can be absorbed by the eccentricity of the inner tube 2 and the outer tube 3 at the bent portion. FIG. 6 shows a case where there is no difference in thermal expansion between the inner and outer tubes (A) and a case where the difference in thermal expansion between the inner and outer tubes is absorbed by the eccentricity of the inner tube 2 and the outer tube 3 (B).

  The number of the bent portions 23 can be determined based on the diameter, length, material, use conditions, etc. of the transport pipe. When the inner tube 2 and the outer tube 3 are made of stainless steel, the number of the bent portions 23 should be one at a time when the length of the transport tube 1 is up to 30 m and one every time the length exceeds 30 m. Is preferred.

  If the installation interval of the support member 4 (a in FIG. 2) is too short, the amount of heat transfer through the support member increases, and if it is too long, the inner tube 2 and the outer tube 3 are likely to come into contact with each other. The distance a between the support members is preferably in the range of 1.5 to 2 m.

  However, it is preferable not to provide the support member 4 at the bent portion 23. This is because if the support member is installed at the bent portion, the difference in thermal expansion between the inner and outer tubes cannot be absorbed well. Also, in the straight portion of the transport pipe 1, it is preferable not to provide a support member within a distance of 1 m from the bent portion 23, and it is more preferable not to provide a support member within 0.5 m.

  Next, a method for transporting a pharmaceutical solution using the pharmaceutical solution transport tube 1 and the pharmaceutical solution transport apparatus 20 according to the present embodiment will be described with reference to FIG.

  Before starting the transportation of the pharmaceutical solution, pure steam at about 132 ° C. is generated by the pure steam generator 24 and is circulated through the flow path 6 of the transport pipe 1 for sterilization. Is discharged from the drain 25. Thereafter, air blowing is performed to circulate dry air in the flow path 6. Next, the vacuum pump 26 is operated to decompress the annular space 7 of the transport pipe 1. Next, the liquid medicine to be transported is supplied from the flow path inlet 21 and transported through the flow path 6 to the flow path outlet 22. At this time, transportation may be stopped for about 5 to 10 minutes due to cooperation with the front and back processes, etc., but the temperature of the pharmaceutical solution in the flow path 6 increases due to the annular space 7 functioning as a heat insulating layer. Is moderate and can be suppressed to an extent that does not cause a problem. When the medical solution is completely discharged from the channel outlet 22 and the transportation is completed, the inside of the channel 6 is again cleaned and sterilized using pure steam, and the vapor and condensed water are discharged from the train 25.

  During transportation of a medical fluid, transportation may be stopped for a long time due to some trouble or the like. At that time, if the temperature of the drug solution staying in the flow path 6 is excessively increased, the expensive drug solution may be altered and wasted. If the refrigerant can be circulated and cooled as in the medical liquid transport pipe shown in FIG. 3, the temperature of the medical liquid will not rise. However, in this embodiment, since the temperature rise of the drug solution in the flow path 6 is prevented only by the heat insulating property of the annular space 7 of the transport pipe 1, the temperature of the drug solution rises above the allowable limit when the stop is continued for a long time. It can happen. Therefore, when the transportation of the pharmaceutical liquid is stopped for a long time, it is preferable that cold air is circulated through the annular space 7 to suppress the temperature rise of the pharmaceutical liquid staying in the flow path 6.

  The experimental apparatus shown in FIG. 5 was assembled and the temperature change of the water during and after transportation was measured using water instead of the pharmaceutical solution.

  First, the experimental apparatus of FIG. 5 will be described. The cross-sectional structure of the transport pipe is the same as in FIG. The inner pipe 2 is made of stainless steel and has a general gas pipe standard 15A (outer diameter 21.7 mm, inner diameter 17.5 mm). The outer pipe 3 is made of stainless steel and is JIS G3447 standard 1.5S (outer diameter 38.1 mm, An inner diameter of 35.7 mm) was used. The support member 4 was made of stainless steel and was cut into a shape having a thickness of 1 mm as shown in FIG. 1 and fixed to the inner tube 2 by welding. The transport pipe 1 has a total length of 30 m, and is formed as a single continuous pipe by welding pipes as materials, and there is no connection portion by a flange or the like in the middle. In the middle of the route of the transport pipe 1, bent portions 23 are provided at two places, and the lengths of the three straight portions are about 14.5 m, about 1 m, and about 14.5 m, respectively. The entire path of the transport pipe is given a 1/100 gradient, and gradually falls from the flow path inlet 21 to the flow path outlet 22. A pure steam production machine 24 and a compressed air supply machine 35 are connected to the flow path 6, and a drain 25 is provided. A pressure sensor PR5, a vacuum pump 26, and an air cooler 27 are connected to the annular space 7. In addition, temperature sensors TR1 to TR5, T6, and TR7 are installed at various places in the apparatus.

(Experiment 1) In Experiment 1, the pressure of the annular space 7 (PR5) was reduced to an atmospheric pressure ratio of -0.097 MPa, and the water temperature was circulated at a flow rate of about 10 L / min. TR1) and the channel outlet 22 (TR2). Water in the water storage tank 31 is cooled by a handy cooler 32 and stirred by a stirrer 33. Water is supplied from the water storage tank 31 to the transport pipe 1 from the flow path inlet 21 by the liquid feed pump 34, discharged from the flow path outlet 22, and returns to the water storage tank 31 through the hose 40. When calculated from the diameter and length of the flow path, the water circulates in an average of about 1 minute.

(Experiment 2) In Experiment 2, the same measurement as Experiment 1 was performed while circulating the water at a flow rate of about 10 L / min without reducing the pressure in the annular space 7.

  Table 1 shows the experimental conditions and results of Experiment 1 and Experiment 2. The temperature rise of water during transport (TR2-TR1) was 0.43 ° C. and 0.35 ° C., respectively, and was sufficiently small in both experiments. From this, in this experimental apparatus, when the pharmaceutical solution is transported without stagnation, it can be determined that the temperature rise of the pharmaceutical solution during transportation is small even if the annular space 7 is not decompressed.

(Experiment 3) Experiment 3 was carried out following Experiment 1, and the circulation of water was stopped while the annular space 7 was decompressed, and the water in the vicinity of the flow path outlet 22 was reached after 8 and 60 minutes. It was measured how many times the temperature (TR2) increased.

(Experiment 4) Experiment 4 was performed under the same conditions as Experiment 3.

(Experiment 5) Experiment 5 was performed following Experiment 2, and the same measurement as Experiment 3 was performed while the annular space 7 was maintained at atmospheric pressure.

(Experiment 6) In Experiment 6, after the circulation of water was stopped, the same measurement as in Experiment 3 was performed while circulating the cold / warm air through the annular space 7. The cool / warm air was cooled by passing through the air cooler 27 after removing dust and the like through the vent filter 38. Cold air of about 10 ° C. is circulated through the air cooler 27, and the air that has passed through the air cooler is cooled to about 10 ° C. In Experiment 6, the surface temperature (TR7) of the cold / hot air supply pipe was 11.6 ° C. In the experiment, cold / warm air was sucked into the annular space 7 and circulated while operating the vacuum pump 24. Therefore, the pressure in the annular space (PR5) was slightly lower than the atmospheric pressure (−0.005 MPa).

  The experimental conditions and results of Experiment 3 to Experiment 6 are shown in Table 2.

  First, it is confirmed how much the temperature of the water has increased due to the 8-minute circulation stoppage that can occur even under normal transportation conditions.

  In Experiment 3 and Experiment 4 in which the annular space 7 was decompressed, the water temperature rise (TR2, 8-TR2, 0) for 8 minutes after the circulation was stopped was about 1 ° C. From this, it can be determined that if the annular space 7 is decompressed, an increase in the temperature of the pharmaceutical solution does not cause a problem even if the transportation of the pharmaceutical solution is stopped for 8 minutes. On the other hand, in Experiment 5 in which the annular space was atmospheric pressure, the temperature rise of water (TR2, 8-TR2, 0) was 2.84 ° C. From this, when the annular space 7 is not decompressed, the temperature rise of the pharmaceutical solution during transportation is small unless the transportation is stopped (Experiment 2), but if the transportation is stopped for 8 minutes, Temperature rise can be a problem.

  In Experiment 6 in which cold / warm air was circulated through the annular space, the temperature rise (TR2, 8-TR2, 0) of water was as large as 2.64 ° C. This is because the water temperature (TR2, 0) at the time of circulation stop was 2.36 ° C, but the temperature of the circulated air was about 10 ° C (≈TR6) due to experimental restrictions. This is probably because the water staying in the flow path was warmed. The distribution of cold / warm air will be described later.

  Next, although it does not occur under normal transportation conditions, assuming that the transportation is interrupted due to some trouble, it is confirmed how much the temperature of the water has increased due to the circulation stop for 60 minutes.

  In Experiment 3 and Experiment 4, the water temperature rise (TR2, 60-TR2, 0) for 60 minutes after the circulation was stopped was 3.92 ° C and 3.44 ° C, respectively. This value cannot be said to be in an acceptable range depending on the type of pharmaceutical liquid to be transported. On the other hand, the water temperature rise (TR2, 60-TR2, 0) in Experiment 5 was 13.72 ° C., which was clearly unacceptable.

  In Experiment 6, the temperature rise of water (TR2, 60-TR2, 0) was not as small as 6.96 ° C, but here the temperature after 60 minutes (TR2, 60) was 9.32 ° C and cold air. It should be noted that this is close to the temperature. Comparing Experiment 5 and Experiment 6, the water temperature rise (TR2,8-TR2,0) for 8 minutes after the circulation stop was 2.84 ° C in Experiment 5 and 2.64 ° C in Experiment 6, both of which were almost It was the same. On the other hand, the temperature rise (TR2, 60-TR2, 0) of water for 60 minutes after the circulation stop was about half at 6.96 ° C in Experiment 6 compared to 13.72 ° C in Experiment 5. In Experiment 6, it is understood that the temperature of water staying in the flow path 6 is suppressed from becoming higher than the temperature of the cold / warm air by circulating the cold / warm air.

  From this result, it was found that the effect of cooling the inner tube 2 sufficiently and preventing the temperature rise of the pharmaceutical solution staying in the flow path 6 can be obtained also by circulating the cool / warm air through the annular space 7. A preferred method of using cold / warm air is considered as follows. First, the temperature of the air cooler 27 is appropriately set to 5 ° C., for example. When the transportation of the medical liquid is interrupted, first, the pressure rise in the annular space 7 is maintained, and the temperature rise of the medical liquid staying in the flow path 6 is suppressed. When the stopped state continues and the temperature of the pharmaceutical solution rises to near 5 ° C., the circulation of cold / warm air is started. Thereafter, by continuing the circulation of the cold and hot air, it is possible to suppress the temperature of the pharmaceutical solution from rising further.

1 Drug transport tube 2 Inner tube 3 Outer tube
DESCRIPTION OF SYMBOLS 4 Support member 6 Pharmaceutical liquid flow path 7 Annular space 11 Conventional pharmaceutical liquid transport pipe 12 Inner pipe 13 Outer pipe 15 Thermal insulation material 16 Pharmaceutical liquid flow path 17 Refrigerant flow path 18 Unit of conventional pharmaceutical liquid transport pipe 20 Pharmaceutical liquid transport apparatus 21 Channel inlet 22 Channel outlet 23 Bent part of transport pipe 24 Pure steam generator 25 Drain 26 Vacuum pump 27 Air cooler (cold air supply machine)
28 Pressure sensor 29 Temperature sensor 30 Experimental device 31 Water storage tank 32 Handy cooler (water cooling device)
33 Stirrer 34 Liquid feed pump 35 Compressed air supply machine 38 Vent filter 39 Exhaust port 40 Hose PR5 Pressure sensor in the annular space 7 TR1 Temperature sensor in the flow path 6 and near the inlet TR2 Temperature sensor in the flow path 6 and near the outlet TR3 Temperature sensor on the outer tube 3 surface (front)
TR4 Temperature sensor on the outer tube 3 surface (after stage)
TR5 Temperature sensor on outer tube 3 surface (middle)
T6 Temperature sensor in the water storage tank 31 TR7 Temperature sensor on the surface of the cold air supply pipe

Claims (6)

An inner tube, an outer tube, and a support member for holding a gap between the inner tube and the outer tube;
The inside of the inner pipe is a flow path for transported goods,
An annular space sandwiched between the inner tube and the outer tube is formed to be depressurized,
A pharmaceutical solution transporting pipe characterized by having a bent part in the middle of the route. The support member is fixed to the inner pipe, not fixed to the outer pipe,
The pharmaceutical liquid transport pipe according to claim 1, wherein the support member is provided in a portion other than the bent portion of the transport pipe. The pharmaceutical liquid transport pipe according to claim 1 or 2, wherein the inner pipe does not have a bellows-like expansion joint. The pharmaceutical liquid transport tube according to any one of claims 1 to 3,
A pharmaceutical liquid transport apparatus, comprising: an air cooler for supplying cold and warm air to the annular space of the pharmaceutical liquid transport pipe. A method for transporting a pharmaceutical liquid using the pharmaceutical liquid transport pipe according to any one of claims 1 to 3, wherein the step of supplying pure vapor to the flow path of the pharmaceutical liquid transport pipe;
Depressurizing the annular space;
And a step of circulating the medicinal liquid through the flow path while decompressing the annular space. The temperature rise of the pharmaceutical liquid staying in the flow path is suppressed by supplying cold / warm air to the annular space of the pharmaceutical liquid transport pipe when the transportation of the pharmaceutical liquid is stopped. A method for transporting a pharmaceutical solution.

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