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JP2013056083A5
JP2013056083A5 JP2011196897A JP2011196897A JP2013056083A5 JP 2013056083 A5 JP2013056083 A5 JP 2013056083A5 JP 2011196897 A JP2011196897 A JP 2011196897A JP 2011196897 A JP2011196897 A JP 2011196897A JP 2013056083 A5 JP2013056083 A5 JP 2013056083A5
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生体の脈波の測定期間である第１測定期間と第２測定期間とにおける、前記生体を透過した又は前記生体で反射した第１の波長の光を受光した受光量に基づく第１測定信号、及び前記生体を透過した又は前記生体で反射した第２の波長の光を受光した受光量に基づく第２測定信号とを取得する取得手段と、
前記第１測定期間と前記第２測定期間における前記第１測定信号と第２測定信号とから、第１周波数成分の信号と、前記第１周波数成分の周波数帯域より低い周波数帯域の第２周波数成分の信号とを抽出する抽出手段と、
前記抽出手段によって抽出された前記第１測定期間及び前記第２測定期間における前記第１周波数成分の信号と前記第２周波数成分の信号とに基づき前記第２測定信号と前記第１測定信号との相関を表す第１係数と第２係数とを算出し、前記第１係数と前記第２係数との差に応じて、前記第１係数及び前記第２係数を用いて前記第２測定期間における前記第１測定信号と前記第２測定信号に含まれる脈動成分とノイズ成分とを分離する分離処理と、前記第２測定期間における前記第２測定信号の前記第１周波数成分を前記脈動成分とする処理とを選択的に行い、前記第２測定期間における前記脈動成分を出力する出力手段と
を備えることを特徴とする信号処理装置。 A first measurement signal based on a received light amount of light having a first wavelength transmitted through or reflected by the living body in a first measurement period and a second measurement period, which are measurement periods of a pulse wave of the living body; and obtaining means for obtaining a second measurement signal based on the received light amount of the received light to light of the second wavelength reflected by the transmitted or the biological the biological,
From the first measuring signal in the second measurement period before and Symbol first measurement period and a second measurement signal, a signal of the first frequency component, a second frequency of the lower frequency band than the frequency band of the first frequency component extraction means to extract the component of the signal,
Wherein the first measurement period extracted by the extracting means and the second signal of the first frequency component in the measurement period and the second frequency component of the signal and the based-out the second measurement signal and the first measurement signal The first coefficient and the second coefficient representing the correlation between the first coefficient and the second coefficient are calculated, and the second measurement period is calculated using the first coefficient and the second coefficient according to the difference between the first coefficient and the second coefficient. Separation processing for separating a pulsation component and a noise component included in the first measurement signal and the second measurement signal, and the first frequency component of the second measurement signal in the second measurement period as the pulsation component And an output means for selectively outputting the pulsating component in the second measurement period. 前記出力手段は、下記式(１)によって得られる値を前記第１係数とし、下記式(２)によって得られる値を前記第２係数とすることを特徴とする請求項１に記載の信号処理装置。
Figure 2013056083
 ‖ＲACpulse‖２は第１測定期間の第１測定信号の第１周波数成分のノルムである。
‖ＧACpulse‖２は第１測定期間の第２測定信号の第１周波数成分のノルムである。
‖ＲDCpulse‖２は第１測定期間の第１測定信号の第２周波数成分のノルムである。
‖ＧDCpulse‖２は第１測定期間の第２測定信号の第２周波数成分のノルムである。
‖ＲACnoise(j-k:j+k)‖２は第２測定期間の第１測定信号の第１周波数成分のノルムである。
‖ＧACnoise(j-k:j+k)‖２は第２測定期間の第２測定信号の第１周波数成分のノルムである。
‖ＲDCnoise(j-k:j+k)‖２は第２測定期間の第１測定信号の第２周波数成分のノルムである。
‖ＧDCnoise(j-k:j+k)‖２は第２測定期間の第２測定信号の第２周波数成分のノルムである。 And the output means, and the first coefficient value obtained by the following equation (1), the signal processing according to the value obtained by the following formula (2) in claim 1, characterized in that the said second coefficient apparatus.
Figure 2013056083
 ‖RACpulse‖ 2 is a norm of a first frequency component of the first measurement signal of the first measurement period.
‖GACpulse‖ 2 is a norm of a first frequency component of the second measurement signal of the first measurement period.
‖RDCpulse‖ 2 is a norm of a second frequency component of the first measurement signal of the first measurement period.
‖GDCpulse‖ 2 is a norm of a second frequency component of the second measurement signal of the first measurement period.
‖RACnoise (jk: j + k) || 2 is the norm of the first frequency component of the first measurement signal of the second measurement period.
‖GACnoise (jk: j + k) || 2 is the norm of the first frequency component of the second measurement signal of the second measurement period.
‖RDCnoise (jk: j + k) || 2 is the norm of the second frequency component of the first measurement signal of the second measurement period.
‖GDCnoise (jk: j + k) || 2 is the norm of the second frequency component of the second measurement signal of the second measurement period. 前記第１係数と前記第２係数との差が予め定めた閾値の範囲内である場合には、前記第２測定期間における前記第２測定信号の前記第１周波数成分を前記脈動成分とする処理を行い、前記閾値の範囲外である場合には、前記第１係数と前記第２係数とを用いた前記分離処理を行うことを特徴とする請求項２に記載の信号処理装置。  When the difference between the first coefficient and the second coefficient is within a predetermined threshold range, the process using the first frequency component of the second measurement signal in the second measurement period as the pulsation component 3. The signal processing apparatus according to claim 2, wherein the separation processing using the first coefficient and the second coefficient is performed when the value is outside the range of the threshold value. 4. 前記第２の波長の光は、前記第１の波長の光よりも酸化ヘモグロビンに対して還元ヘモグロビンの吸光係数が小さいことを特徴とする請求項１から３のいずれか一項に記載の信号処理装置。 The light of the second wavelength, the signal processing according to any one of claims 1 to 3, wherein the absorption coefficient of reduced hemoglobin with respect to oxygenated hemoglobin than the light of the first wavelength is small apparatus. 前記第１の波長の光を前記生体に照射し、前記生体を透過した又は前記生体で反射した前記第１の波長の光を受光し、受光量に応じた前記第１測定信号を出力する第１受発光部と、
前記第２の波長の光を前記生体に照射し、前記生体を透過した又は前記生体で反射した前記第２の波長の光を受光し、受光量に応じた前記第２測定信号を出力する第２受発光部と、
前記第１受発光部と前記第２受発光部とから出力された前記第１測定信号及び前記第２測定信号を用いて、前記第２測定期間における脈動成分を出力する請求項１から４のいずれか一項に記載の信号処理装置と
を備えることを特徴とする脈波計測装置。 The said light of the first wavelength is irradiated to the living body, receiving the first light of a wavelength reflected by the transmitted or the biological the biological, and outputs the first measurement signal corresponding to the received light amount 1 light emitting and receiving unit;
The second light having a wavelength of irradiating the living body, and receiving the second light of the wavelength reflected by the transmitted or the biological the biological, and outputs the second measurement signal corresponding to the amount of received light Two light emitting and receiving parts;
Using the first measurement signal and the second measurement signal outputted from the first light receiving and emitting unit and the second light receiving and emitting unit, according to claim 1 from 4 outputting the ripple component in the second measurement period A pulse wave measuring device comprising: the signal processing device according to any one of the above. 測定対象の生体の脈波を測定する第１測定期間と、前記生体の体動の影響を受けている第２測定期間とにおける、前記生体を透過した又は前記生体で反射した第１の波長の光を受光した受光量に基づく第１測定信号、及び前記生体を透過した又は前記生体で反射した第２の波長の光を受光した受光量に基づく第２測定信号とを取得する取得ステップと、
前記第１測定期間及び前記第２測定期間における前記第１測定信号と第２測定信号とから、第１周波数成分の信号と、前記第１周波数成分の周波数帯域より低い周波数帯域の第２周波数成分の信号とを抽出する抽出ステップと、
前記抽出ステップによって抽出された前記第１測定期間及び前記第２測定期間における前記第１周波数成分の信号と前記第２周波数成分の信号とに基づき前記第２測定信号と前記第１測定信号との相関を表す第１係数と第２係数とを算出し、前記第１係数と前記第２係数との差に応じて、前記第１係数及び前記第２係数を用いて前記第２測定期間における前記第１測定信号と前記第２測定信号に含まれる脈動成分とノイズ成分とを分離する分離処理と、前記第２測定期間における前記第２測定信号の前記第１周波数成分を前記脈動成分とする処理とを選択的に行い、前記第２測定期間における前記脈動成分を出力する出力ステップと
を有することを特徴とする信号処理方法。 A first measurement period for measuring the pulse wave of the measurement target living body, in a second measurement period that is affected by the body movement of the living body, first wavelength reflected by the transmitted or the biological the biological an obtaining step of obtaining a second measurement signal based on the first measurement signal, and a light receiving amount of receiving light of the second wavelength reflected by the transmitted or the biological the biological based on the amount of received light and receiving light,
From the first measurement signal before Symbol first measurement period and the second measurement period and a second measurement signal, a signal of the first frequency component, a second frequency of the lower frequency band than the frequency band of the first frequency component An extraction step for extracting component signals;
Signal and the second frequency component of the signal and based-out the second measurement signal to said first measuring signal of the first frequency component in the first measurement period and the second measurement period extracted by the extraction step The first coefficient and the second coefficient representing the correlation between the first coefficient and the second coefficient are calculated, and the second measurement period is calculated using the first coefficient and the second coefficient according to the difference between the first coefficient and the second coefficient. Separation processing for separating a pulsation component and a noise component included in the first measurement signal and the second measurement signal, and the first frequency component of the second measurement signal in the second measurement period as the pulsation component And a step of outputting the pulsation component in the second measurement period selectively. 生体の脈波の測定期間である第１測定期間と、前記生体の体動の影響を受けている第２測定期間とにおける、前記生体を透過した又は前記生体で反射した第１の波長の光を受光Light having a first wavelength transmitted through the living body or reflected by the living body in a first measuring period, which is a measurement period of the pulse wave of the living body, and in a second measuring period, which is affected by body movement of the living body Receive light
した受光量に基づく第１測定信号、及び前記生体を透過した又は前記生体で反射した第２の波長の光を受光した受光量に基づく第２測定信号とを取得する取得手段と、An acquisition means for acquiring a first measurement signal based on the received light amount and a second measurement signal based on the received light amount of light having a second wavelength transmitted through or reflected by the living body;
前記第１測定期間及び前記第２測定期間における前記第１測定信号と第２測定信号とから、第１周波数成分の信号と、前記第１周波数成分の周波数帯域より低い周波数帯域の第２周波数成分の信号を抽出する抽出手段と、From the first measurement signal and the second measurement signal in the first measurement period and the second measurement period, a signal of a first frequency component and a second frequency component in a frequency band lower than the frequency band of the first frequency component Extracting means for extracting the signal of
前記抽出手段によって抽出された前記第１測定期間及び前記第２測定期間における、の前記第１周波数成分の信号と前記第２周波数成分の信号に基づき前記第２測定信号と前記第１測定信号との相関を表す第１係数及び第２係数とを算出し、前記第１係数と前記第２係数とを用いて、前記第２測定期間における前記第１測定信号と前記第２測定信号とに含まれる脈動成分とノイズ成分とを分離する分離手段とThe second measurement signal and the first measurement signal based on the signal of the first frequency component and the signal of the second frequency component in the first measurement period and the second measurement period extracted by the extraction unit, And calculating the first coefficient and the second coefficient representing the correlation of the first measurement signal and using the first coefficient and the second coefficient, and including the first coefficient and the second coefficient in the second measurement period. Separating means for separating the generated pulsation component and noise component
を備えることを特徴とする信号処理装置。A signal processing apparatus comprising: 前記分離手段は、前記第１測定期間における前記第２測定信号に対する前記第１測定信号の前記第１周波数成分と前記第２周波数成分の各値を加算した値を前記第１係数とし、前記第２測定期間における前記第２測定信号に対する前記第１測定信号の第１周波数成分と前記第２周波数成分の各値を加算した値を前記第２係数として用いることを特徴とする請求項７に記載の信号処理装置。The separating means sets a value obtained by adding each value of the first frequency component and the second frequency component of the first measurement signal to the second measurement signal in the first measurement period as the first coefficient, and The value obtained by adding each value of the first frequency component and the second frequency component of the first measurement signal with respect to the second measurement signal in two measurement periods is used as the second coefficient. Signal processing equipment. 生体の脈波の測定期間である第１測定期間と、前記生体の体動の影響を受けている第２測定期間とにおける、前記生体を透過した又は前記生体で反射した第１の波長の光を受光した受光量に基づく第１測定信号、及び前記生体を透過した又は前記生体で反射した第２の波長の光を受光した受光量に基づく第２測定信号を取得する取得ステップと、Light having a first wavelength transmitted through the living body or reflected by the living body in a first measuring period, which is a measurement period of the pulse wave of the living body, and in a second measuring period, which is affected by body movement of the living body Obtaining a first measurement signal based on the amount of received light received, and a second measurement signal based on the amount of received light having received the second wavelength of light transmitted through or reflected by the living body;
前記第１測定期間及び前記第２測定期間における前記第１測定信号と第２測定信号とから、第１周波数成分の信号と、前記第１周波数成分の周波数帯域より低い周波数帯域の第２周波数成分の信号を抽出する抽出ステップと、From the first measurement signal and the second measurement signal in the first measurement period and the second measurement period, a signal of a first frequency component and a second frequency component in a frequency band lower than the frequency band of the first frequency component An extraction step for extracting the signal of
前記抽出ステップによって抽出された前記第１測定期間と前記第２測定期間の前記第１周波数成分の信号と前記第２周波数成分の信号に基づき前記第２測定信号と前記第１測定信号との相関を表す第１係数及び第２係数を算出し、前記第１係数及び前記第２係数を用いて、前記第２測定期間における前記第１測定信号と前記第２測定信号に含まれる脈動成分とノイズ成分とを分離する分離ステップとCorrelation between the second measurement signal and the first measurement signal based on the first frequency component signal and the second frequency component signal of the first measurement period and the second measurement period extracted by the extraction step. The first coefficient and the second coefficient representing the pulsation component and noise included in the first measurement signal and the second measurement signal in the second measurement period are calculated using the first coefficient and the second coefficient. Separating step to separate the components and
を有することを特徴とする信号処理方法。A signal processing method characterized by comprising:
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