JP2013019720A5 - - Google Patents

Download PDF

Info

Publication number
JP2013019720A5
JP2013019720A5 JP2011151897A JP2011151897A JP2013019720A5 JP 2013019720 A5 JP2013019720 A5 JP 2013019720A5 JP 2011151897 A JP2011151897 A JP 2011151897A JP 2011151897 A JP2011151897 A JP 2011151897A JP 2013019720 A5 JP2013019720 A5 JP 2013019720A5
Authority
JP
Japan
Prior art keywords
target substance
detection
detection target
sensor chamber
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011151897A
Other languages
Japanese (ja)
Other versions
JP5948746B2 (en
JP2013019720A (en
Filing date
Publication date
Application filed filed Critical
Priority to JP2011151897A priority Critical patent/JP5948746B2/en
Priority claimed from JP2011151897A external-priority patent/JP5948746B2/en
Publication of JP2013019720A publication Critical patent/JP2013019720A/en
Publication of JP2013019720A5 publication Critical patent/JP2013019720A5/ja
Application granted granted Critical
Publication of JP5948746B2 publication Critical patent/JP5948746B2/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Claims (8)

1センサー室を有し、前記第1センサー室内に導入された流体試料中の検出対象物質を検出する第1検出部と、
第2センサー室を有し、前記第1センサー室から前記第2センサー室に導入された前記流体試料中の前記検出対象物質を検出する第2検出部と、
前記第1センサー室から前記第2センサー室に前記流体試料を導く流路と、
前記第1,第2検出部にて前記検出対象物質がそれぞれ検出された時間に基づいて、前記検出対象物質を定量分析する定量分析部と、
を有することを特徴とする検出装置。
A first detector which has a first sensors chamber, for detecting the target substance in the fluid sample introduced into the first sensor chamber,
A second detection unit that has a second sensor chamber and detects the detection target substance in the fluid sample introduced from the first sensor chamber into the second sensor chamber;
A flow path for guiding the fluid sample from the first sensor chamber to the second sensor chamber;
A quantitative analysis unit that quantitatively analyzes the detection target substance based on times when the detection target substances are respectively detected by the first and second detection units;
A detection apparatus comprising:
請求項1において、
前記定量分析部は、前記第1,第2センサー室にて前記検出対象物質がそれぞれ検出された時間T1,T2の時間差(T2−T1)と、前記第1,第2センサー室間の距離X1とに基づいて、前記検出対象物質を定量分析することを特徴とする検出装置。
In claim 1,
The quantitative analysis unit includes a time difference (T2−T1) between times T1 and T2 when the detection target substances are detected in the first and second sensor chambers, and a distance X1 between the first and second sensor chambers. And a quantitative analysis of the substance to be detected based on the above.
請求項2において、
前記流路に設けられたバルブをさらに有し、
前記バルブは、前記第1センサー室にて前記検出対象物質が検出された信号に基づいて開放されることを特徴とする検出装置。
In claim 2,
A valve provided in the flow path;
The detection device according to claim 1, wherein the valve is opened based on a signal in which the detection target substance is detected in the first sensor chamber.
請求項3において、
前記バルブは、前記第1センサー室にて前記検出対象物質が検出された時間T1より後であって前記第2センサー室にて前記検出対象物質が検出された時間T2より前の時間T3に開放され、
前記定量分析部は、前記時間差(T2−T1)及び前記距離X1に代えて、時間差(T2−T3)と、前記バルブと前記第2センサー室との間の距離X2とに基づいて、前記検出対象物質を定量分析することを特徴とする検出装置。
In claim 3,
The valve opens at a time T3 after a time T1 when the detection target substance is detected in the first sensor chamber and before a time T2 when the detection target substance is detected in the second sensor chamber. And
The quantitative analysis unit detects the detection based on the time difference (T2-T3) and the distance X2 between the valve and the second sensor chamber instead of the time difference (T2-T1) and the distance X1. A detection apparatus characterized by quantitative analysis of a target substance.
請求項1乃至4のいずれかにおいて、
前記第1検出部及び前記第2検出部の各々は、
1〜1000nmの凸部を有する金属ナノ構造と、
前記金属ナノ構造に光を照射する光源と、
前記光源からの光に基づいて前記金属ナノ構造に吸着された前記検出対象物質から発せられる光を検出する光検出部と、
を備えることを特徴とする検出装置。
In any one of Claims 1 thru | or 4,
Each of the first detector and the second detector is
A metal nanostructure having a convex part of 1 to 1000 nm;
A light source for irradiating the metal nanostructure with light;
A light detection unit for detecting light emitted from the detection target substance adsorbed on the metal nanostructure based on light from the light source;
A detection apparatus comprising:
請求項において、
前記第1検出部は、前記金属ナノ構造に吸着された前記検出対象物質を脱離させる脱離部をさらに備えることを特徴とする検出装置。
In claim 5 ,
The first detection unit further includes a desorption unit that desorbs the detection target substance adsorbed on the metal nanostructure.
請求項6において、
前記脱離部は、前記光検出部が前記前記検出対象物質から発せられる光を検出した信号に基づいて、脱離動作が開始されることを特徴とする検出装置。
In claim 6,
The desorption unit starts a desorption operation based on a signal that the light detection unit detects light emitted from the detection target substance.
請求項2において、
前記第1検出部は、
1〜1000nmの凸部を有する金属ナノ構造と、
前記金属ナノ構造に光を照射する光源と、
前記光源からの光に基づいて前記金属ナノ構造に吸着された前記検出対象物質から発せられる光を検出する光検出部と、
前記金属ナノ構造に吸着された前記検出対象物質を脱離させる脱離部と、
をさらに備え、
前記脱離部は、前記第1センサー室にて前記検出対象物質が検出された時間T1より後であって前記第2センサー室にて前記検出対象物質が検出された時間T2より前の時間T3に脱離が開始され、
前記定量分析部は、前記時間差(T2−T1)に代えて、時間差(T2−T3)に基づいて前記検出対象物質を定量分析することを特徴とする検出装置。
In claim 2,
The first detection unit includes:
A metal nanostructure having a convex part of 1 to 1000 nm;
A light source for irradiating the metal nanostructure with light;
A light detection unit for detecting light emitted from the detection target substance adsorbed on the metal nanostructure based on light from the light source;
A desorption part for desorbing the detection target substance adsorbed on the metal nanostructure;
Further comprising
The desorption portion is a time T3 after the time T1 when the detection target substance is detected in the first sensor chamber and before the time T2 when the detection target substance is detected in the second sensor chamber. Desorption begins,
The quantitative analysis unit quantitatively analyzes the detection target substance based on a time difference (T2-T3) instead of the time difference (T2-T1).
JP2011151897A 2011-07-08 2011-07-08 Detection device Expired - Fee Related JP5948746B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2011151897A JP5948746B2 (en) 2011-07-08 2011-07-08 Detection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011151897A JP5948746B2 (en) 2011-07-08 2011-07-08 Detection device

Publications (3)

Publication Number Publication Date
JP2013019720A JP2013019720A (en) 2013-01-31
JP2013019720A5 true JP2013019720A5 (en) 2014-08-14
JP5948746B2 JP5948746B2 (en) 2016-07-06

Family

ID=47691307

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011151897A Expired - Fee Related JP5948746B2 (en) 2011-07-08 2011-07-08 Detection device

Country Status (1)

Country Link
JP (1) JP5948746B2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017138340A (en) * 2017-05-22 2017-08-10 セイコーエプソン株式会社 Detection device
KR102469917B1 (en) * 2021-05-24 2022-11-23 한국과학기술원 Apparatus for measuring particle and method for measuring particle

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3482128B2 (en) * 1998-06-30 2003-12-22 三菱電機株式会社 Anomaly detection device
US7361313B2 (en) * 2003-02-18 2008-04-22 Intel Corporation Methods for uniform metal impregnation into a nanoporous material
US20050266582A1 (en) * 2002-12-16 2005-12-01 Modlin Douglas N Microfluidic system with integrated permeable membrane
JP4926780B2 (en) * 2007-03-27 2012-05-09 東京瓦斯株式会社 Physical property change estimation method, physical property change estimation program, and physical property change estimation device in gas conduit
JP2009109395A (en) * 2007-10-31 2009-05-21 Fujifilm Corp Method of manufacturing fine structure, fine structure, device for raman spectrum, raman spectrometer, analyzing device, detection device and mass spectrometer
JP4897054B2 (en) * 2008-01-16 2012-03-14 日本電信電話株式会社 Flow velocity measuring device, antigen concentration measuring device, flow velocity measuring method, antigen concentration measuring method
US8564781B2 (en) * 2008-09-01 2013-10-22 Hitachi Chemical Company, Ltd. SPR sensor

Similar Documents

Publication Publication Date Title
JP2009500621A5 (en)
WO2010004436A3 (en) Enhanced immunoassay sensor
CY1121291T1 (en) SIGNAL STRENGTHENING IMMEDIATES
JP2013527917A5 (en)
WO2011093602A3 (en) Centrifugal micro-fluidic device and method for detecting analytes from liquid specimen
RU2018124339A (en) METHOD AND SYSTEM FOR SENSOR DETECTION BY MEANS OF MODIFIED NANOSTRUCTURE
CL2012003569A1 (en) Method for determining an inclination of a component of an industrial machine, which comprises the detection of a first and second magnetic flow, the generation of a first and second flow signal, analysis of the first and second flow signal, identification of a path of magnetic sensor, and the determination of the inclination of the component of the industrial machine; Insdustrial machine
PH12018502389A1 (en) Immunochromatography analysis device for detecting zika virus
EP2685266A4 (en) Bead sealing method, method for detecting target molecule, array, kit, and target molecule detection device
WO2007002480A3 (en) Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
WO2012129164A3 (en) Biosensor
EP2397839A3 (en) Particle concentration measuring device
GB2497697A (en) Magnetic nanoparticle detection across a membrane
IN2015DN04062A (en)
JP2017524934A5 (en)
WO2007124085A3 (en) Device for quantification of radioisotope concentrations in a micro-fluidic platform
BR112014014844A2 (en) method and device for the detection and analysis of deposits
JP2013231686A5 (en)
JP2013019720A5 (en)
IN2014DN07535A (en)
WO2013106598A3 (en) Localized surface plasmon resonance mercury detection system and methods
WO2015069340A3 (en) Chemical sensing device
JP2016534358A5 (en)
JP2011518338A5 (en)
FR3006692B1 (en) DEVICE, SYSTEM AND DETECTION METHOD FOR DETECTING THE PRESENCE OF A MICROORGANISM IN A SAMPLE INSIDE A CONTAINER