IN2014DN07535A - - Google Patents

Info

Publication number
IN2014DN07535A
IN2014DN07535A IN7535DEN2014A IN2014DN07535A IN 2014DN07535 A IN2014DN07535 A IN 2014DN07535A IN 7535DEN2014 A IN7535DEN2014 A IN 7535DEN2014A IN 2014DN07535 A IN2014DN07535 A IN 2014DN07535A
Authority
IN
India
Prior art keywords
sensor
ros
barrier layer
sensing region
analyte
Prior art date
Application number
Inventor
William Paterson
Nick Barwell
Bruce Culbert
Barry Colin Crane
Original Assignee
Lightship Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lightship Medical Ltd filed Critical Lightship Medical Ltd
Publication of IN2014DN07535A publication Critical patent/IN2014DN07535A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A61B5/14735—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter comprising an immobilised reagent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/206664—Ozone or peroxide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Abstract

A sensor (1) or detecting and/or quantifying the amount of analyte in a sample the sensor including: • a sensing region (3); and • a barrier layer (BL) including a reactive oxygen species (ROS) quenching analyte permeable membrane having an ROS quenching agent adsorbed thereto; • wherein the sensor is adapted so that the sample enters the sensing region of the sensor through said barrier layer.
IN7535DEN2014 2012-03-15 2013-02-20 IN2014DN07535A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261611239P 2012-03-15 2012-03-15
PCT/GB2013/050407 WO2013136044A2 (en) 2012-03-15 2013-02-20 Sensor

Publications (1)

Publication Number Publication Date
IN2014DN07535A true IN2014DN07535A (en) 2015-04-24

Family

ID=47833300

Family Applications (1)

Application Number Title Priority Date Filing Date
IN7535DEN2014 IN2014DN07535A (en) 2012-03-15 2013-02-20

Country Status (8)

Country Link
US (3) US8940542B2 (en)
EP (1) EP2825095A2 (en)
JP (1) JP2015509803A (en)
CN (1) CN104168827A (en)
AU (1) AU2013234126A1 (en)
CA (2) CA2867092C (en)
IN (1) IN2014DN07535A (en)
WO (1) WO2013136044A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101959067B1 (en) 2011-03-15 2019-03-15 센세오닉스, 인코포레이티드 Integrated catalytic protection of oxidation sensitive materials
IN2014DN07535A (en) * 2012-03-15 2015-04-24 Lightship Medical Ltd
US9017622B2 (en) * 2012-04-10 2015-04-28 Lightship Medical Limited Calibrator for a sensor
US11109779B2 (en) 2012-12-28 2021-09-07 Senseonics, Incorporated Chemical modification of analyte permeable membrane for enhanced oxidative stability
CN105628756B (en) * 2015-12-30 2018-09-21 南京工业大学 A kind of preparation method of blood separated in synchronization and sensing membrane
CN110346341A (en) * 2019-08-08 2019-10-18 生态环境部华南环境科学研究所 A kind of active o content automatic checkout system

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63291596A (en) * 1987-05-22 1988-11-29 Meidensha Electric Mfg Co Ltd Determination of glucose in biospecimen
US6387672B1 (en) 2000-12-04 2002-05-14 Beckman Coulter, Inc. Photo-induced electron transfer fluorescent sensor molecules
SE0200269D0 (en) * 2002-01-31 2002-01-31 Ellem Bioteknik Ab Material for implantation
US20040063167A1 (en) * 2002-07-12 2004-04-01 Peter Kaastrup Minimising calibration problems of in vivo glucose sensors
US7761130B2 (en) * 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
JP2005315871A (en) * 2004-03-31 2005-11-10 Terumo Corp Intracorporeal substance measuring assembly, manufacturing method for intracorporeal substance measuring assembly, and embedded type substance sensor
US7450980B2 (en) 2004-03-31 2008-11-11 Terumo Kabushiki Kaisha Intracorporeal substance measuring assembly
US8541146B2 (en) * 2005-01-12 2013-09-24 Toyota Motor Engineering & Manufacturing North America, Inc. Photocatalytic methods for preparation of electrocatalyst materials
ITFI20050002A1 (en) * 2005-01-11 2006-07-12 Acta Spa ASSEMBLED MAMBRANA-ELECTRODES FOR FUEL CELLS, THEIR MANUFACTURE AND USE AND FUEL CELLS THAT COUNT
US20070014726A1 (en) 2005-07-18 2007-01-18 Sensors For Medicine And Science Oxidation-resistant indicator macromolecule
US20070154466A1 (en) 2005-12-30 2007-07-05 Jan Weber Internal medical devices containing peroxide-converting catalysts
WO2008066921A2 (en) 2006-11-30 2008-06-05 Sensors For Medicine And Science, Inc. Oxidation resistant indicator molecules
EP2989975B1 (en) 2007-02-06 2018-06-13 Medtronic MiniMed, Inc. Optical systems and methods for rationmetric measurement of blood glucose concentration
US8088097B2 (en) 2007-11-21 2012-01-03 Glumetrics, Inc. Use of an equilibrium intravascular sensor to achieve tight glycemic control
WO2008141241A1 (en) 2007-05-10 2008-11-20 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
GB0715590D0 (en) 2007-08-09 2007-09-19 Glysure Ltd Sensing apparatus
GB0906318D0 (en) 2009-04-09 2009-05-20 Glysure Ltd Fluorophore and fluorescent sensor compound containing same
CN102460715B (en) 2009-04-21 2015-07-22 泰特拉桑有限公司 High-efficiency solar cell structures and methods of manufacture
TW201041612A (en) 2009-04-21 2010-12-01 Sensors For Med & Science Inc Protective shell for an in vivo sensor made from resorbable polymer
WO2010123896A2 (en) * 2009-04-21 2010-10-28 Washington University Palladium-platinum nanostructures and methods for their preparation
DK2534470T3 (en) * 2010-02-08 2016-12-05 Medtronic Minimed Inc Antioxidant protection of a chemical sensor
WO2011101626A1 (en) * 2010-02-16 2011-08-25 Glysure Ltd Barrier layer for glusose sensor
JP2013519894A (en) 2010-02-19 2013-05-30 ライトシップ メディカル リミテッド Indicator system for fiber optic sensors
EP2545373B1 (en) 2010-03-11 2022-08-24 Medtronic Minimed, Inc. Measuring analyte concentration incorporating temperature and ph correction
WO2013024260A1 (en) 2011-08-17 2013-02-21 Lightship Medical Limited Barrier layer for glucose sensor
IN2014DN07535A (en) 2012-03-15 2015-04-24 Lightship Medical Ltd

Also Published As

Publication number Publication date
US20170010274A1 (en) 2017-01-12
AU2013234126A1 (en) 2014-09-25
US9797909B2 (en) 2017-10-24
CN104168827A (en) 2014-11-26
CA2867092A1 (en) 2013-09-19
US9476886B2 (en) 2016-10-25
WO2013136044A3 (en) 2013-12-27
US8940542B2 (en) 2015-01-27
WO2013136044A2 (en) 2013-09-19
CA3095821A1 (en) 2013-09-19
US20150219663A1 (en) 2015-08-06
EP2825095A2 (en) 2015-01-21
JP2015509803A (en) 2015-04-02
CA2867092C (en) 2022-12-13
CA3095821C (en) 2023-03-14
US20140234982A1 (en) 2014-08-21

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