JP2012527438A - 正常駆出率心不全の治療 - Google Patents

正常駆出率心不全の治療 Download PDF

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Publication number
JP2012527438A
JP2012527438A JP2012511329A JP2012511329A JP2012527438A JP 2012527438 A JP2012527438 A JP 2012527438A JP 2012511329 A JP2012511329 A JP 2012511329A JP 2012511329 A JP2012511329 A JP 2012511329A JP 2012527438 A JP2012527438 A JP 2012527438A
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JP
Japan
Prior art keywords
patients
exercise
perhexiline
heart
energy
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Pending
Application number
JP2012511329A
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English (en)
Japanese (ja)
Other versions
JP2012527438A5 (enExample
Inventor
アシュラフィアン,ホーマン
フレノー,マイケル,ポール
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heart Metabolics Ltd
Original Assignee
Heart Metabolics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heart Metabolics Ltd filed Critical Heart Metabolics Ltd
Publication of JP2012527438A publication Critical patent/JP2012527438A/ja
Publication of JP2012527438A5 publication Critical patent/JP2012527438A5/ja
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4458Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
JP2012511329A 2009-05-20 2009-05-20 正常駆出率心不全の治療 Pending JP2012527438A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2009/050539 WO2010133815A1 (en) 2009-05-20 2009-05-20 Treatment of heart failure with normal ejection fraction

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015075231A Division JP2015147787A (ja) 2015-04-01 2015-04-01 正常駆出率心不全の治療

Publications (2)

Publication Number Publication Date
JP2012527438A true JP2012527438A (ja) 2012-11-08
JP2012527438A5 JP2012527438A5 (enExample) 2014-07-24

Family

ID=41213178

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012511329A Pending JP2012527438A (ja) 2009-05-20 2009-05-20 正常駆出率心不全の治療

Country Status (11)

Country Link
US (3) US8440697B2 (enExample)
EP (1) EP2432470A1 (enExample)
JP (1) JP2012527438A (enExample)
CN (1) CN102573844A (enExample)
AU (1) AU2009346606B2 (enExample)
BR (1) BRPI0924398A2 (enExample)
CA (1) CA2816448A1 (enExample)
IL (1) IL216362A0 (enExample)
MX (1) MX2011012310A (enExample)
WO (1) WO2010133815A1 (enExample)
ZA (1) ZA201109332B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0405381D0 (en) 2004-03-10 2004-04-21 Univ Wales Medicine A method and means for treating heart failure
GB0908193D0 (en) 2009-05-13 2009-06-24 Albright Patents Treatment of disease state
EP2432470A1 (en) 2009-05-20 2012-03-28 Heart Metabolics Limited Treatment of heart failure with normal ejection fraction
AU2012297569B2 (en) 2011-08-16 2017-11-09 Baker Heart and Diabetes Institute Controlled-release formulation
EP2892529A4 (en) * 2012-09-05 2016-01-20 Adelaide Res &Innovation Pty Ltd USES OF (-) - PERHEXILINE
MX2017008248A (es) * 2014-12-22 2018-02-19 Cardiora Pty Ltd Metodo de tratamiento.
BR112019012214A8 (pt) 2016-12-15 2023-03-28 Baxter Int Sistema e método para monitorar e determinar parâmetros do paciente a partir de forma de onda venosa detectada
US11039754B2 (en) 2018-05-14 2021-06-22 Baxter International Inc. System and method for monitoring and determining patient parameters from sensed venous waveform

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007528378A (ja) * 2004-03-10 2007-10-11 ハート メタボリクス リミテッド 慢性心不全を治療するためのペルヘキシリン

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN380695A0 (en) 1995-06-23 1995-07-20 Queen Elizabeth Hospital, The Methods related to the treatment of and isolation of compounds for treatment of ischaemic conditions
US20030162824A1 (en) * 2001-11-12 2003-08-28 Krul Elaine S. Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor
CL2004000366A1 (es) * 2003-02-26 2005-01-07 Pharmacia Corp Sa Organizada B USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA.
AU2005230811A1 (en) 2004-04-06 2005-10-20 Angiogenetics Sweden Ab Angiogenesis-affecting compounds and methods of use thereof
PL1959951T3 (pl) 2005-12-01 2010-06-30 Hoffmann La Roche Heteroarylo-podstawione pochodne piperydyny jako inhibitory l-cpt1
ITRM20060090A1 (it) 2006-02-22 2007-08-23 Sigma Tau Ind Farmaceuti Nuovi composti inibitori cpt a livello del snc come farmaci antidiabetici e o antiobesita
GB0723100D0 (en) * 2007-11-23 2008-01-02 Heart Metabolics Ltd Treatment of HFnEF
GB0908193D0 (en) * 2009-05-13 2009-06-24 Albright Patents Treatment of disease state
EP2432470A1 (en) 2009-05-20 2012-03-28 Heart Metabolics Limited Treatment of heart failure with normal ejection fraction
US20140019207A1 (en) 2012-07-11 2014-01-16 Sap Ag Interactive in-memory based sales forecasting
EP2892529A4 (en) 2012-09-05 2016-01-20 Adelaide Res &Innovation Pty Ltd USES OF (-) - PERHEXILINE
WO2015131231A1 (en) 2014-03-03 2015-09-11 Adelaide Research & Innovation Pty Ltd Methods for using (-)-perhexiline

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007528378A (ja) * 2004-03-10 2007-10-11 ハート メタボリクス リミテッド 慢性心不全を治療するためのペルヘキシリン

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CSNC201000308024; 大塚 美里: '心エコ-を用いた心不全の病態解析と重症度判定 Echacardiographic evaluation of ventricular systol' 医学のあゆみ 第216巻、第1号, 2006, 第99-104頁 *
JPN5012013363; COATS C J: 'CURRENT MANAGEMENT OF HYPERTROPHIC CARDIOMYOPATHY' Current Treatment Options in Cardiovascular Medicine V10 N6, 2008, P496-504 *
JPN6013059053; K. Yamamoto, et. al.: 'Heart Failure With Preserved Ejection Fraction-What is Known and Unknown-' Circulation Journal Vol.73, 200903, p.404-410 *
JPN6013059055; 大塚 美里: '心エコ-を用いた心不全の病態解析と重症度判定 Echacardiographic evaluation of ventricular systol' 医学のあゆみ 第216巻、第1号, 2006, 第99-104頁 *

Also Published As

Publication number Publication date
AU2009346606B2 (en) 2016-06-02
US20100331364A1 (en) 2010-12-30
US9457017B2 (en) 2016-10-04
MX2011012310A (es) 2012-04-11
US8440697B2 (en) 2013-05-14
US20130210720A1 (en) 2013-08-15
CN102573844A (zh) 2012-07-11
CA2816448A1 (en) 2010-11-25
US20130210719A1 (en) 2013-08-15
WO2010133815A1 (en) 2010-11-25
BRPI0924398A2 (pt) 2019-09-24
ZA201109332B (en) 2012-08-29
AU2009346606A1 (en) 2012-01-19
IL216362A0 (en) 2012-01-31
US9468634B2 (en) 2016-10-18
EP2432470A1 (en) 2012-03-28

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