BRPI0924398A2 - perexilina, metodo de tratamento de hfnef e programa de tratamento para tratar hfnef - Google Patents

perexilina, metodo de tratamento de hfnef e programa de tratamento para tratar hfnef

Info

Publication number
BRPI0924398A2
BRPI0924398A2 BRPI0924398A BRPI0924398A BRPI0924398A2 BR PI0924398 A2 BRPI0924398 A2 BR PI0924398A2 BR PI0924398 A BRPI0924398 A BR PI0924398A BR PI0924398 A BRPI0924398 A BR PI0924398A BR PI0924398 A2 BRPI0924398 A2 BR PI0924398A2
Authority
BR
Brazil
Prior art keywords
hfnef
treatment
perexillin
treating
treatment method
Prior art date
Application number
BRPI0924398A
Other languages
English (en)
Inventor
Ashrafian Houman
Paul Frenneaux Michael
Original Assignee
Heart Metabolics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heart Metabolics Ltd filed Critical Heart Metabolics Ltd
Publication of BRPI0924398A2 publication Critical patent/BRPI0924398A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4458Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
BRPI0924398A 2009-05-20 2009-05-20 perexilina, metodo de tratamento de hfnef e programa de tratamento para tratar hfnef BRPI0924398A2 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2009/050539 WO2010133815A1 (en) 2009-05-20 2009-05-20 Treatment of heart failure with normal ejection fraction

Publications (1)

Publication Number Publication Date
BRPI0924398A2 true BRPI0924398A2 (pt) 2019-09-24

Family

ID=41213178

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0924398A BRPI0924398A2 (pt) 2009-05-20 2009-05-20 perexilina, metodo de tratamento de hfnef e programa de tratamento para tratar hfnef

Country Status (11)

Country Link
US (3) US8440697B2 (pt)
EP (1) EP2432470A1 (pt)
JP (1) JP2012527438A (pt)
CN (1) CN102573844A (pt)
AU (1) AU2009346606B2 (pt)
BR (1) BRPI0924398A2 (pt)
CA (1) CA2816448A1 (pt)
IL (1) IL216362A0 (pt)
MX (1) MX2011012310A (pt)
WO (1) WO2010133815A1 (pt)
ZA (1) ZA201109332B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0405381D0 (en) 2004-03-10 2004-04-21 Univ Wales Medicine A method and means for treating heart failure
GB0908193D0 (en) 2009-05-13 2009-06-24 Albright Patents Treatment of disease state
CA2816448A1 (en) 2009-05-20 2010-11-25 Heart Metabolics Limited Treatment of heart failure with normal ejection fraction
US10137093B2 (en) 2011-08-16 2018-11-27 Cardiora Pty Ltd. Milrinone controlled-release formulation
US20140065241A1 (en) * 2012-09-05 2014-03-06 Adelaide Research & Innovation Pty Ltd Uses of (-)-perhexiline
CN107530337B (zh) 2014-12-22 2021-07-09 贝克心脏与糖尿病研究所 治疗方法
JP6878589B2 (ja) 2016-12-15 2021-05-26 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 感知された静脈波形から患者パラメータを監視および決定するためのシステムおよび方法
US11039754B2 (en) 2018-05-14 2021-06-22 Baxter International Inc. System and method for monitoring and determining patient parameters from sensed venous waveform

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN380695A0 (en) 1995-06-23 1995-07-20 Queen Elizabeth Hospital, The Methods related to the treatment of and isolation of compounds for treatment of ischaemic conditions
US20030162824A1 (en) 2001-11-12 2003-08-28 Krul Elaine S. Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor
CL2004000366A1 (es) 2003-02-26 2005-01-07 Pharmacia Corp Sa Organizada B USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA.
GB0405381D0 (en) 2004-03-10 2004-04-21 Univ Wales Medicine A method and means for treating heart failure
AU2005230811A1 (en) 2004-04-06 2005-10-20 Angiogenetics Sweden Ab Angiogenesis-affecting compounds and methods of use thereof
AU2006319247B2 (en) 2005-12-01 2010-03-11 F. Hoffmann-La Roche Ag Heteroaryl substituted piperidine derivatives as L-CPT1 inhibitors
ITRM20060090A1 (it) 2006-02-22 2007-08-23 Sigma Tau Ind Farmaceuti Nuovi composti inibitori cpt a livello del snc come farmaci antidiabetici e o antiobesita
GB0723100D0 (en) * 2007-11-23 2008-01-02 Heart Metabolics Ltd Treatment of HFnEF
GB0908193D0 (en) 2009-05-13 2009-06-24 Albright Patents Treatment of disease state
CA2816448A1 (en) 2009-05-20 2010-11-25 Heart Metabolics Limited Treatment of heart failure with normal ejection fraction
US20140019207A1 (en) 2012-07-11 2014-01-16 Sap Ag Interactive in-memory based sales forecasting
US20140065241A1 (en) 2012-09-05 2014-03-06 Adelaide Research & Innovation Pty Ltd Uses of (-)-perhexiline
WO2015131231A1 (en) 2014-03-03 2015-09-11 Adelaide Research & Innovation Pty Ltd Methods for using (-)-perhexiline

Also Published As

Publication number Publication date
ZA201109332B (en) 2012-08-29
US9457017B2 (en) 2016-10-04
WO2010133815A1 (en) 2010-11-25
CN102573844A (zh) 2012-07-11
CA2816448A1 (en) 2010-11-25
IL216362A0 (en) 2012-01-31
US20130210719A1 (en) 2013-08-15
MX2011012310A (es) 2012-04-11
US9468634B2 (en) 2016-10-18
US8440697B2 (en) 2013-05-14
US20130210720A1 (en) 2013-08-15
EP2432470A1 (en) 2012-03-28
AU2009346606B2 (en) 2016-06-02
AU2009346606A1 (en) 2012-01-19
JP2012527438A (ja) 2012-11-08
US20100331364A1 (en) 2010-12-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.