JP2012519178A5 - - Google Patents
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- Publication number
- JP2012519178A5 JP2012519178A5 JP2011552157A JP2011552157A JP2012519178A5 JP 2012519178 A5 JP2012519178 A5 JP 2012519178A5 JP 2011552157 A JP2011552157 A JP 2011552157A JP 2011552157 A JP2011552157 A JP 2011552157A JP 2012519178 A5 JP2012519178 A5 JP 2012519178A5
- Authority
- JP
- Japan
- Prior art keywords
- tadalafil
- propylparaben
- characterization
- complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 2
- 238000012512 characterization method Methods 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 229960003415 propylparaben Drugs 0.000 description 1
- IEHKWSGCTWLXFU-IIBYNOLFSA-N tadalafil Chemical compound C1=C2OCOC2=CC([C@@H]2C3=C([C]4C=CC=CC4=N3)C[C@H]3N2C(=O)CN(C3=O)C)=C1 IEHKWSGCTWLXFU-IIBYNOLFSA-N 0.000 description 1
- 229960000835 tadalafil Drugs 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20862409P | 2009-02-26 | 2009-02-26 | |
| US61/208,624 | 2009-02-26 | ||
| PCT/US2010/025421 WO2010099323A1 (en) | 2009-02-26 | 2010-02-25 | Crystalization of pharmaceutical compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015021058A Division JP2015134774A (ja) | 2009-02-26 | 2015-02-05 | 医薬化合物の結晶化 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012519178A JP2012519178A (ja) | 2012-08-23 |
| JP2012519178A5 true JP2012519178A5 (enExample) | 2016-12-15 |
| JP6074142B2 JP6074142B2 (ja) | 2017-02-01 |
Family
ID=42665904
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011552157A Expired - Fee Related JP6074142B2 (ja) | 2009-02-26 | 2010-02-25 | 医薬化合物の結晶化 |
| JP2015021058A Pending JP2015134774A (ja) | 2009-02-26 | 2015-02-05 | 医薬化合物の結晶化 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015021058A Pending JP2015134774A (ja) | 2009-02-26 | 2015-02-05 | 医薬化合物の結晶化 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US8586587B2 (enExample) |
| EP (1) | EP2400848A4 (enExample) |
| JP (2) | JP6074142B2 (enExample) |
| WO (1) | WO2010099323A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6074142B2 (ja) * | 2009-02-26 | 2017-02-01 | タール ファーマシューティカルズ，インコーポレイテッド | 医薬化合物の結晶化 |
| WO2013109223A1 (en) | 2012-01-18 | 2013-07-25 | Mahmut Bilgic | Particulate formulations of tadalafil in effervescent form |
| MX357741B (es) | 2012-07-06 | 2018-07-23 | Laboratorios Senosiain S A De C V Star | Nuevas formas sólidas de inhibidores de fosfodiesterasa tipo 5. |
| CN104086546B (zh) * | 2014-07-14 | 2016-08-17 | 福建广生堂药业股份有限公司 | 他达拉非的药用酸盐及其制备方法 |
| EA035390B1 (ru) | 2014-07-23 | 2020-06-05 | КРКА, д.д., НОВО МЕСТО | Совместный осадок тадалафила с фармацевтически приемлемыми эксципиентами, содержащая его фармацевтическая композиция и способ их получения |
| CN105481860B (zh) * | 2015-12-31 | 2018-03-02 | 山西普德药业有限公司 | 一种他达拉非i型晶体的精制工艺 |
| CN110940755A (zh) * | 2019-12-18 | 2020-03-31 | 山西省食品药品检验所(山西省药品包装材料监测中心) | 一种食品中4种他达拉非类物质的检测方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4490371A (en) * | 1983-02-16 | 1984-12-25 | Syntex (U.S.A.) Inc. | N,N-Disubstituted-(2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-B]quinazolinyl)oxyalkylamides |
| GB9401090D0 (en) | 1994-01-21 | 1994-03-16 | Glaxo Lab Sa | Chemical compounds |
| GB9514464D0 (en) | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Medicaments |
| US6943166B1 (en) | 1999-04-30 | 2005-09-13 | Lilly Icos Llc. | Compositions comprising phosphodiesterase inhabitors for the treatment of sexual disfunction |
| NZ516616A (en) | 1999-08-03 | 2003-07-25 | Lilly Icos Llc | Beta-carboline pharmaceutical compositions |
| US6821975B1 (en) | 1999-08-03 | 2004-11-23 | Lilly Icos Llc | Beta-carboline drug products |
| US7019010B2 (en) | 2001-09-27 | 2006-03-28 | Novertis Ag | Combinations |
| WO2003074474A2 (en) | 2002-03-01 | 2003-09-12 | University Of South Florida | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
| JP5069905B2 (ja) | 2003-01-21 | 2012-11-07 | アプテュイト （ウエスト ラファイエット）、エルエルシー | 新規な共結晶化 |
| JP4842819B2 (ja) * | 2003-09-04 | 2011-12-21 | セフアロン・インコーポレーテツド | モダフィニル組成物 |
| JP5017103B2 (ja) * | 2004-06-17 | 2012-09-05 | トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド | 薬剤共結晶組成物および関連した使用方法 |
| WO2006049986A1 (en) * | 2004-10-28 | 2006-05-11 | Dr. Reddy's Laboratories Ltd. | Polymorphic forms of tadalafil |
| WO2006050458A2 (en) | 2004-11-02 | 2006-05-11 | Teva Pharmaceutical Industries, Ltd. | Tadalafil crystal forms and processes for preparing them |
| NZ577502A (en) * | 2006-12-28 | 2012-02-24 | Hoffmann La Roche | Crystalline forms glyt1 |
| JP6074142B2 (ja) * | 2009-02-26 | 2017-02-01 | タール ファーマシューティカルズ，インコーポレイテッド | 医薬化合物の結晶化 |
-
2010
- 2010-02-25 JP JP2011552157A patent/JP6074142B2/ja not_active Expired - Fee Related
- 2010-02-25 US US13/203,297 patent/US8586587B2/en not_active Expired - Fee Related
- 2010-02-25 EP EP10746835A patent/EP2400848A4/en not_active Withdrawn
- 2010-02-25 WO PCT/US2010/025421 patent/WO2010099323A1/en not_active Ceased
-
2013
- 2013-10-07 US US14/047,463 patent/US9040535B2/en not_active Expired - Fee Related
-
2015
- 2015-02-05 JP JP2015021058A patent/JP2015134774A/ja active Pending
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