JP2012515213A5 - - Google Patents

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Publication number
JP2012515213A5
JP2012515213A5 JP2011546329A JP2011546329A JP2012515213A5 JP 2012515213 A5 JP2012515213 A5 JP 2012515213A5 JP 2011546329 A JP2011546329 A JP 2011546329A JP 2011546329 A JP2011546329 A JP 2011546329A JP 2012515213 A5 JP2012515213 A5 JP 2012515213A5
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JP
Japan
Prior art keywords
cells
individual
combination
antigen
composition
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Application number
JP2011546329A
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English (en)
Japanese (ja)
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JP2012515213A (ja
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Priority claimed from PCT/US2010/021029 external-priority patent/WO2010083298A1/en
Publication of JP2012515213A publication Critical patent/JP2012515213A/ja
Publication of JP2012515213A5 publication Critical patent/JP2012515213A5/ja
Pending legal-status Critical Current

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JP2011546329A 2009-01-14 2010-01-14 免疫応答を増強するための、mTOR阻害剤を含有する方法及び組成物 Pending JP2012515213A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14453709P 2009-01-14 2009-01-14
US61/144,537 2009-01-14
US29309610P 2010-01-07 2010-01-07
US61/293,096 2010-01-07
PCT/US2010/021029 WO2010083298A1 (en) 2009-01-14 2010-01-14 Methods and compositions containing mtor inhibitors for enhancing immune responses

Publications (2)

Publication Number Publication Date
JP2012515213A JP2012515213A (ja) 2012-07-05
JP2012515213A5 true JP2012515213A5 (cg-RX-API-DMAC7.html) 2012-12-27

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ID=42340082

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011546329A Pending JP2012515213A (ja) 2009-01-14 2010-01-14 免疫応答を増強するための、mTOR阻害剤を含有する方法及び組成物

Country Status (6)

Country Link
US (1) US20100196311A1 (cg-RX-API-DMAC7.html)
EP (1) EP2375897A4 (cg-RX-API-DMAC7.html)
JP (1) JP2012515213A (cg-RX-API-DMAC7.html)
CN (1) CN102281761A (cg-RX-API-DMAC7.html)
CA (1) CA2748931A1 (cg-RX-API-DMAC7.html)
WO (1) WO2010083298A1 (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011133636A1 (en) 2010-04-20 2011-10-27 Cedars-Sinai Medical Center COMBINATION THERAPY WITH CD4 LYMPHOCYTE DEPLETION AND mTOR INHIBITORS
CN104338129B (zh) * 2013-07-26 2017-05-24 中国科学院上海巴斯德研究所 雷帕霉素作为疫苗佐剂的用途及制备方法
US20150140036A1 (en) * 2013-11-13 2015-05-21 Novartis Institutes For Biomedical Research, Inc. Low, immune enhancing, dose mtor inhibitors and uses thereof
WO2015120198A1 (en) 2014-02-05 2015-08-13 Cedars-Sinai Medical Center Methods and compositions for treating cancer and infectious diseases
EP3171882A1 (en) 2014-07-21 2017-05-31 Novartis AG Treatment of cancer using a cll-1 chimeric antigen receptor
US10174095B2 (en) 2014-07-21 2019-01-08 Novartis Ag Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor
HK1245095A1 (zh) 2015-05-20 2018-08-24 Novartis Ag 依维莫司(everolimus)与达托里昔布(dactolisib)的医药组合
EA201890159A1 (ru) * 2015-06-29 2018-11-30 АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи СПОСОБЫ ЛЕЧЕНИЯ ГЕМАТОЛОГИЧЕСКОГО ЗЛОКАЧЕСТВЕННОГО НОВООБРАЗОВАНИЯ С ПОМОЩЬЮ КОМБИНИРОВАННОЙ ТЕРАПИИ ИНГИБИТОРОМ mTOR В ВИДЕ НАНОЧАСТИЦ
AU2016285720C1 (en) 2015-06-29 2022-02-03 Abraxis Bioscience, Llc Methods of treating epithelioid cell tumors
EP3324983A4 (en) 2015-07-20 2019-04-10 Mayo Foundation for Medical Education and Research METHOD AND MATERIALS FOR PRODUCING T-CELLS
EP3405568A4 (en) * 2016-01-20 2019-12-04 Fate Therapeutics, Inc. COMPOUNDS AND METHODS FOR IMMUNOCELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES
CN108473959B (zh) 2016-01-20 2023-04-21 菲特治疗公司 用来在过继性免疫疗法中进行免疫细胞调节的组合物和方法
WO2018096402A1 (en) 2016-11-23 2018-05-31 Novartis Ag Methods of enhancing immune response with everolimus, dactolisib or both
EP3548049A4 (en) * 2016-12-05 2020-07-22 Fate Therapeutics, Inc. COMPOSITIONS AND METHODS FOR MODULATION OF IMMUNE CELLS IN ADOPTIVE IMMUNOTHERAPIES
WO2019157516A1 (en) 2018-02-12 2019-08-15 resTORbio, Inc. Combination therapies
MY208825A (en) 2018-06-13 2025-05-30 Novartis Ag Bcma chimeric antigen receptors and uses thereof
CN110412289B (zh) * 2019-07-25 2022-08-02 北京美迪阿姆科技发展有限公司 抑制性t细胞及筛选方法和抑制自身免疫反应中的应用
CN114426952A (zh) * 2020-10-29 2022-05-03 中国科学技术大学 用于白血病的car t细胞疗法的t细胞增效剂及获得增效t细胞的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3066599A (en) * 1998-03-03 1999-10-18 University Of Southern California Use of cytokines and mitogens to inhibit graft versus host disease
US7198789B2 (en) * 1998-03-17 2007-04-03 Genetics Institute, Llc Methods and compositions for modulating interleukin-21 receptor activity
WO2005003335A2 (en) * 2003-06-12 2005-01-13 Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Rapamycin resistant t cells and therapeutic uses thereof
WO2003038062A2 (en) * 2001-10-31 2003-05-08 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Generation of use of tc1 and tc2 cells
US7718196B2 (en) * 2001-07-02 2010-05-18 The United States Of America, As Represented By The Department Of Health And Human Services Rapamycin-resistant T cells and therapeutic uses thereof
US20060094674A1 (en) * 2002-07-05 2006-05-04 Neel Benjamin G Combination of mtor inhibitor and a tyrosine kinase inhibitor for the treatment of neoplasms
PT1408106E (pt) * 2002-10-11 2007-04-30 Sentoclone Ab Imunoterapia de cancro
KR20140019032A (ko) * 2006-04-05 2014-02-13 노파르티스 아게 암을 치료하기 위한 치료제의 조합물
WO2008042814A2 (en) * 2006-09-29 2008-04-10 California Institute Of Technology Mart-1 t cell receptors
US8765462B2 (en) * 2007-05-04 2014-07-01 University Health Network IL-12 immunotherapy for cancer
CA2733203A1 (en) * 2008-08-05 2010-02-11 Emory University Use of mtor inhibitors to enhance t cell immune responses

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