JP2012510802A - 完全ヒトインフルエンザｍ２特異的抗体 - Google Patents
完全ヒトインフルエンザｍ２特異的抗体 Download PDFInfo
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
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- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
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- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08170749.9 | 2008-12-04 | ||
| EP08170749 | 2008-12-04 | ||
| EP09173548.0 | 2009-10-20 | ||
| EP09173548 | 2009-10-20 | ||
| PCT/EP2009/066052 WO2010063675A1 (en) | 2008-12-04 | 2009-11-30 | Fully human influenza m2 specific antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012510802A true JP2012510802A (ja) | 2012-05-17 |
| JP2012510802A5 JP2012510802A5 (enExample) | 2013-02-14 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011538980A Ceased JP2012510802A (ja) | 2008-12-04 | 2009-11-30 | 完全ヒトインフルエンザｍ２特異的抗体 |
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| Country | Link |
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| US (2) | US8460670B2 (enExample) |
| EP (1) | EP2365827A1 (enExample) |
| JP (1) | JP2012510802A (enExample) |
| CN (1) | CN102238963A (enExample) |
| AU (1) | AU2009324251A1 (enExample) |
| CA (1) | CA2745598A1 (enExample) |
| WO (1) | WO2010063675A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2220116B1 (en) | 2007-11-12 | 2012-09-05 | Theraclone Sciences, Inc. | Compositions and methods for the therapy and diagnosis of influenza |
| JP2012510802A (ja) * | 2008-12-04 | 2012-05-17 | インターセル アーゲー | 完全ヒトインフルエンザｍ２特異的抗体 |
| AU2010249787A1 (en) * | 2009-05-20 | 2011-12-22 | Theraclone Sciences, Inc. | Compositions and methods for the therapy and diagnosis of influenza |
| JP2014506580A (ja) * | 2011-02-14 | 2014-03-17 | セラクローン サイエンシーズ， インコーポレイテッド | インフルエンザの治療および診断のための組成物および方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2005519619A (ja) * | 2002-03-13 | 2005-07-07 | 麒麟麦酒株式会社 | インフルエンザｍ２タンパク質に対するヒトモノクローナル抗体および上記抗体を作製しかつ利用する方法 |
| JP2008522610A (ja) * | 2004-12-06 | 2008-07-03 | キリンファーマ株式会社 | インフルエンザｍ２タンパク質に対するヒトモノクローナル抗体及びその生産方法及びその使用 |
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| US6197502B1 (en) | 1997-11-17 | 2001-03-06 | Cytos Biotechnology Ag | Expression cloning processes for the discovery characterization, and isolation of genes encoding polypeptides with a predetermined property |
| US6686168B1 (en) | 1999-11-04 | 2004-02-03 | Zymogenetics, Inc. | Cell surface display of proteins by recombinant host cells |
| US20050170334A1 (en) | 2002-03-13 | 2005-08-04 | Toshifumi Mikayama | Human monoclonal antibodies to influenza M2 protein and methods of making and using same |
| US8003106B2 (en) | 2002-03-13 | 2011-08-23 | Kyowa Hakko Kirin Co., Ltd. | Human monoclonal antibodies to influenza M2 protein and methods of making and using same |
| EP1921142A1 (en) | 2006-11-07 | 2008-05-14 | Cytos Biotechnology AG | Selection of human monoclonal antibodies by eukaryotic cell display |
| JP2012510802A (ja) | 2008-12-04 | 2012-05-17 | インターセル アーゲー | 完全ヒトインフルエンザｍ２特異的抗体 |
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2009
- 2009-11-30 JP JP2011538980A patent/JP2012510802A/ja not_active Ceased
- 2009-11-30 AU AU2009324251A patent/AU2009324251A1/en not_active Abandoned
- 2009-11-30 EP EP09768353A patent/EP2365827A1/en not_active Withdrawn
- 2009-11-30 CN CN2009801487074A patent/CN102238963A/zh active Pending
- 2009-11-30 CA CA2745598A patent/CA2745598A1/en not_active Abandoned
- 2009-11-30 WO PCT/EP2009/066052 patent/WO2010063675A1/en not_active Ceased
- 2009-11-30 US US13/132,658 patent/US8460670B2/en not_active Expired - Fee Related
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2012
- 2012-12-27 US US13/728,056 patent/US20130109845A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005519619A (ja) * | 2002-03-13 | 2005-07-07 | 麒麟麦酒株式会社 | インフルエンザｍ２タンパク質に対するヒトモノクローナル抗体および上記抗体を作製しかつ利用する方法 |
| JP2008522610A (ja) * | 2004-12-06 | 2008-07-03 | キリンファーマ株式会社 | インフルエンザｍ２タンパク質に対するヒトモノクローナル抗体及びその生産方法及びその使用 |
Non-Patent Citations (1)
| Title |
|---|
| JPN6013049500; Ａｎｔｉｖｉｒａｌ Ｒｅｓｅａｒｃｈ ｖｏｌ．８０, 2008, ｐ．１６８-１７７ * |
Also Published As
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| EP2365827A1 (en) | 2011-09-21 |
| AU2009324251A1 (en) | 2010-06-10 |
| CA2745598A1 (en) | 2010-06-10 |
| US20130109845A1 (en) | 2013-05-02 |
| WO2010063675A1 (en) | 2010-06-10 |
| US20110268740A1 (en) | 2011-11-03 |
| US8460670B2 (en) | 2013-06-11 |
| CN102238963A (zh) | 2011-11-09 |
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